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Описание

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Адвантан мазь, 0.1%, 15 мл, 15 г

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4.9
(18)
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Объем, мл: 15

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Вес, г: 15

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Коротко о товаре

Артикул Маркета
3176288499
Тип препарата
Назначение
Действующее вещество
Возраст
от 4 месяцев
Инструкция
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Взрослым и детям с 4-х месячного возраста. Препарат наносят 1 раз в сутки тонким слоем на пораженные участки кожи.\u003Cbr\u003EКак правило, длительность непрерывного ежедневного лечения Адвантаном не должна превышать 12 недель для взрослых и 4-х недель для детей.\u003Cbr\u003EПри подостром или хроническом течении воспалительных заболеваний кожи, не сопровождающихся мокнутием, необходима лекарственная форма с уравновешенным соотношением жира и воды.\u003Cbr\u003E Мазь Адвантан оказывает лечебное действие, способствуя, также устранению сухости кожи и восстановлению её нормальной жирности."},{"name":"Побочные действия","value":"Обычно препарат хорошо переносится.\u003Cbr\u003EОчень редко (менее чем в 0,01% случаев) могут наблюдаться местные реакции, такие как зуд, жжение, эритема, образование везикулёзной сыпи.\u003Cbr\u003E Если препарат применяют более 4-х недель и/или на площади 10% и более поверхности тела, могут возникнуть следующие реакции: атрофия кожи, телеангиэктазии, стрии, акнеформные изменения кожи, системные эффекты, обусловленные абсорбцией кортикостероида.\u003Cbr\u003E В ходе клинических исследований ни один из вышеперечисленных побочных эффектов не был отмечен при применении жирной мази Адвантан до 12 недель у взрослых и до 4-х недель у детей.\u003Cbr\u003EВ редких случаях (0,01% - 0,1%) может наблюдаться фолликулит, гипертрихоз, периоральный дерматит, депигментация кожи, аллергические реакции на один из компонентов препарата."},{"name":"Фармакологическое действие","value":"Активный компонент препарата Адвантан - метилпреднизолона ацепонат - представляет собой негалогенизированный стероид.\u003Cbr\u003EПри наружном применении Адвантан подавляет воспалительные и аллергические кожные реакции, также как и реакции, связанные с усиленной пролиферацией, что приводит к уменьшению объективных симптомов воспаления (эритема, отек, мокнутие и т.д.) и субъективных ощущений (зуд, раздражение, боль и т.д.).\u003Cbr\u003EПри применении метилпреднизолона ацепоната наружно в рекомендуемой дозе, системное действие минимально как у человека, так и у животных.\u003Cbr\u003E После многократного нанесения Адвантана на большие поверхности (40 - 60% поверхности кожи), а также применении под окклюзионную повязку не отмечается нарушений функций надпочечников: уровень кортизола в плазме и его циркадный ритм остаются в пределах нормы, снижения уровня кортизола в суточной моче не происходит.\u003Cbr\u003EВ ходе клинических исследований при применении Адвантана до 12 недель у взрослых и до 4 недель у детей (в том числе, раннего возраста) не было выявлено развития атрофии кожи, телеангиэктазий, стрий и угреподобных высыпаний.\u003Cbr\u003EМетилпреднизолона ацепонат (особенно, его основной метаболит - 6α-метилпреднизолон-17-пропионат) связывается с внутриклеточными глюкокортикостероидными рецепторами.\u003Cbr\u003E Стероид-рецепторный комплекс связывается с определенными участками ДНК клеток иммунного ответа, таким образом, вызывая серию биологических эффектов.\u003Cbr\u003EВ частности, связывание стероид-рецепторного комплекса с ДНК клетками иммунного ответа приводит к индукции синтеза макрокортина. Макрокортин ингибирует высвобождение арахидоновой кислоты и, тем самым, образование медиаторов воспаления типа простагландинов и лейкотриенов.\u003Cbr\u003E Ингибирование глюкокортикостероидами синтеза вазодилатирующих простагландинов и потенцирование сосудосуживающего действия адреналина, приводят к вазоконстрикторному эффекту."},{"name":"Фармакологическая группа","value":"глюкокортикостероид для местного применения"},{"name":"Форма выпуска","value":"мазь"},{"name":"Способ применения/введения","value":"наружный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-allergii","categoryId":"15756502","navnodeId":"72464","glfilters":["35947170:36763741"]}}},{"name":"Минимальный возраст применения","value":"от 4 месяцев"},{"name":"Условия хранения","value":"Хранить при температуре не выше 25°С.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"При изучении острой токсичности метилпреднизолона ацепоната не было выявлено какого-либо риска острой интоксикации при чрезмерном однократном кожном применении (нанесении препарата на большую площадь при условиях, благоприятных для абсорбции) или непреднамеренном приеме внутрь.\u003Cbr\u003EПри чрезмерно долгом и/или интенсивном применении глюкокортикостероидов может развиться атрофия кожи (истончение кожи, телеангиэктазии, стрии).\u003Cbr\u003EПри появлении атрофии препарат необходимо отменить."},{"name":"Применение при беременности и кормлении грудью","value":"При необходимости применения мази Адвантан во время беременности и лактации следует тщательно взвешивать потенциальный риск для плода и ожидаемую пользу лечения для матери.\u003Cbr\u003E В эти периоды не рекомендуется длительное применение препарата на обширных поверхностях кожи.\u003Cbr\u003EКормящим матерям не следует наносить препарат на молочные железы."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Не выявлено."},{"name":"Особые указания","value":"При наличии бактериальных осложнений и/или дерматомикозов в дополнение к терапии Адвантаном необходимо проводить специфическое антибактериальное и/или антимикотическое лечение.\u003Cbr\u003EСледует избегать попадания препарата в глаза.\u003Cbr\u003EКак и в случае применения системных глюкокортикостероидов, после наружного применения глюкокортикостероидов может развиться глаукома (например, при применении больших доз, или очень длительного применения окклюзионных повязок или нанесения на кожу вокруг глаз)."},{"name":"Взаимодействие","value":"Не выявлено."},{"name":"Регистрационный номер","value":"П N013563/04"},{"name":"Дата государственной регистрации","value":"10.04.2023"},{"name":"Владелец регистрационного удостоверения","value":"LEO Pharma A/S","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-allergii","categoryId":"15756502","navnodeId":"72464","glfilters":["34324371:35649313","7893318:18263130"]}}},{"name":"Изготовитель","value":"LEO Pharma Manufacturing Italy S.r.l."},{"name":"Страна бренда","value":"Дания"},{"name":"Страна-производитель","value":"Италия"},{"name":"Название препарата","value":"Адвантан","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-allergii","categoryId":"15756502","navnodeId":"72464","glfilters":["17796364:17878939"]}}},{"name":"Срок годности","value":"36 мес."}]}},"fullSpecsGrouped":{"7617320423654824295":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Органы и системы","value":"кожа"},{"name":"Назначение","value":"аллергический дерматит, атопический дерматит, контактный дерматит, нейродермит, себорея, экзема"},{"name":"Показания к применению","value":"Воспалительные заболевания кожи, чувствительные к терапии топическими глюкокортикостероидами:\u003Cbr\u003Eатопический дерматит, нейродермит, детская экзема;\u003Cbr\u003Eистинная экзема;\u003Cbr\u003Eмикробная экзема;\u003Cbr\u003Eпрофессиональная экзема;\u003Cbr\u003Eпростой контактный дерматит;\u003Cbr\u003Eаллергический (контактный) дерматит;\u003Cbr\u003Eдисгидротическая экзема."},{"name":"Противопоказания","value":"Туберкулезный или сифилитический процессы в области нанесения препарата;\u003Cbr\u003Eвирусные заболевания (например, ветряная оспа, опоясывающий лишай), в области нанесения препарата;\u003Cbr\u003Eрозацеа, периоральный дерматит в области нанесения препарата;\u003Cbr\u003Eдетский возраст до 4-х месяцев;\u003Cbr\u003Eучастки кожи с проявлениями реакции на вакцинацию;\u003Cbr\u003Eгиперчувствительность к компонентам препарата."},{"name":"Состав","value":"1 г мази содержит:\u003Cbr\u003EДействующее вещество: метилпреднизолона ацепонат 0,001 г.\u003Cbr\u003EВспомогательные вещества:\u003Cbr\u003Eпарафин белый мягкий - 0,350 г, парафин жидкий - 0,239 г, воск пчелиный белый - 0,040 г, эмульгатор Дехимулс Е - 0,070 г, вода очищенная - 0,300 г."},{"name":"Действующее вещество","value":"Метилпреднизолона ацепонат"},{"name":"Способ применения и дозы","value":"Наружно. Взрослым и детям с 4-х месячного возраста. Препарат наносят 1 раз в сутки тонким слоем на пораженные участки кожи.\u003Cbr\u003EКак правило, длительность непрерывного ежедневного лечения Адвантаном не должна превышать 12 недель для взрослых и 4-х недель для детей.\u003Cbr\u003EПри подостром или хроническом течении воспалительных заболеваний кожи, не сопровождающихся мокнутием, необходима лекарственная форма с уравновешенным соотношением жира и воды.\u003Cbr\u003E Мазь Адвантан оказывает лечебное действие, способствуя, также устранению сухости кожи и восстановлению её нормальной жирности."},{"name":"Побочные действия","value":"Обычно препарат хорошо переносится.\u003Cbr\u003EОчень редко (менее чем в 0,01% случаев) могут наблюдаться местные реакции, такие как зуд, жжение, эритема, образование везикулёзной сыпи.\u003Cbr\u003E Если препарат применяют более 4-х недель и/или на площади 10% и более поверхности тела, могут возникнуть следующие реакции: атрофия кожи, телеангиэктазии, стрии, акнеформные изменения кожи, системные эффекты, обусловленные абсорбцией кортикостероида.\u003Cbr\u003E В ходе клинических исследований ни один из вышеперечисленных побочных эффектов не был отмечен при применении жирной мази Адвантан до 12 недель у взрослых и до 4-х недель у детей.\u003Cbr\u003EВ редких случаях (0,01% - 0,1%) может наблюдаться фолликулит, гипертрихоз, периоральный дерматит, депигментация кожи, аллергические реакции на один из компонентов препарата."},{"name":"Фармакологическое действие","value":"Активный компонент препарата Адвантан - метилпреднизолона ацепонат - представляет собой негалогенизированный стероид.\u003Cbr\u003EПри наружном применении Адвантан подавляет воспалительные и аллергические кожные реакции, также как и реакции, связанные с усиленной пролиферацией, что приводит к уменьшению объективных симптомов воспаления (эритема, отек, мокнутие и т.д.) и субъективных ощущений (зуд, раздражение, боль и т.д.).\u003Cbr\u003EПри применении метилпреднизолона ацепоната наружно в рекомендуемой дозе, системное действие минимально как у человека, так и у животных.\u003Cbr\u003E После многократного нанесения Адвантана на большие поверхности (40 - 60% поверхности кожи), а также применении под окклюзионную повязку не отмечается нарушений функций надпочечников: уровень кортизола в плазме и его циркадный ритм остаются в пределах нормы, снижения уровня кортизола в суточной моче не происходит.\u003Cbr\u003EВ ходе клинических исследований при применении Адвантана до 12 недель у взрослых и до 4 недель у детей (в том числе, раннего возраста) не было выявлено развития атрофии кожи, телеангиэктазий, стрий и угреподобных высыпаний.\u003Cbr\u003EМетилпреднизолона ацепонат (особенно, его основной метаболит - 6α-метилпреднизолон-17-пропионат) связывается с внутриклеточными глюкокортикостероидными рецепторами.\u003Cbr\u003E Стероид-рецепторный комплекс связывается с определенными участками ДНК клеток иммунного ответа, таким образом, вызывая серию биологических эффектов.\u003Cbr\u003EВ частности, связывание стероид-рецепторного комплекса с ДНК клетками иммунного ответа приводит к индукции синтеза макрокортина. Макрокортин ингибирует высвобождение арахидоновой кислоты и, тем самым, образование медиаторов воспаления типа простагландинов и лейкотриенов.\u003Cbr\u003E Ингибирование глюкокортикостероидами синтеза вазодилатирующих простагландинов и потенцирование сосудосуживающего действия адреналина, приводят к вазоконстрикторному эффекту."},{"name":"Фармакологическая группа","value":"глюкокортикостероид для местного применения"},{"name":"Форма выпуска","value":"мазь"},{"name":"Способ применения/введения","value":"наружный"},{"name":"Минимальный возраст применения","value":"от 4 месяцев"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"Хранить при температуре не выше 25°С.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"При изучении острой токсичности метилпреднизолона ацепоната не было выявлено какого-либо риска острой интоксикации при чрезмерном однократном кожном применении (нанесении препарата на большую площадь при условиях, благоприятных для абсорбции) или непреднамеренном приеме внутрь.\u003Cbr\u003EПри чрезмерно долгом и/или интенсивном применении глюкокортикостероидов может развиться атрофия кожи (истончение кожи, телеангиэктазии, стрии).\u003Cbr\u003EПри появлении атрофии препарат необходимо отменить."},{"name":"Применение при беременности и кормлении грудью","value":"При необходимости применения мази Адвантан во время беременности и лактации следует тщательно взвешивать потенциальный риск для плода и ожидаемую пользу лечения для матери.\u003Cbr\u003E В эти периоды не рекомендуется длительное применение препарата на обширных поверхностях кожи.\u003Cbr\u003EКормящим матерям не следует наносить препарат на молочные железы."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Не выявлено."},{"name":"Особые указания","value":"При наличии бактериальных осложнений и/или дерматомикозов в дополнение к терапии Адвантаном необходимо проводить специфическое антибактериальное и/или антимикотическое лечение.\u003Cbr\u003EСледует избегать попадания препарата в глаза.\u003Cbr\u003EКак и в случае применения системных глюкокортикостероидов, после наружного применения глюкокортикостероидов может развиться глаукома (например, при применении больших доз, или очень длительного применения окклюзионных повязок или нанесения на кожу вокруг глаз)."},{"name":"Взаимодействие","value":"Не выявлено."},{"name":"Регистрационный номер","value":"П N013563/04"},{"name":"Дата государственной регистрации","value":"10.04.2023"},{"name":"Владелец регистрационного удостоверения","value":"LEO Pharma A/S"},{"name":"Изготовитель","value":"LEO Pharma Manufacturing Italy S.r.l."},{"name":"Страна бренда","value":"Дания"},{"name":"Страна-производитель","value":"Италия"},{"name":"Название препарата","value":"Адвантан"},{"name":"Срок годности","value":"36 мес."}]}],"transitionId":"tr_12016999657591554293"}}}}
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Макрокортин ингибирует высвобождение арахидоновой кислоты и, тем самым, образование медиаторов воспаления типа простагландинов и лейкотриенов.\u003Cbr\u003E Ингибирование глюкокортикостероидами синтеза вазодилатирующих простагландинов и потенцирование сосудосуживающего действия адреналина, приводят к вазоконстрикторному эффекту."},{"description":"","filters":[{"id":34045110,"name":"Фармакологическая группа"}],"isMainProperty":false,"name":"Фармакологическая группа","value":"глюкокортикостероид для местного применения"},{"description":"","filters":[{"id":27141511,"name":"Форма выпуска для карточки"}],"isMainProperty":false,"name":"Форма выпуска","value":"мазь"},{"description":"","filters":[{"id":35947170,"name":"Способ применения/введения"}],"isMainProperty":false,"name":"Способ применения/введения","value":"наружный"},{"description":"","filters":[{"id":23679511,"name":"Минимальный возраст применения"},{"id":16082123,"name":"С рождения"}],"isMainProperty":false,"name":"Минимальный возраст применения","value":"от 4 месяцев"}]},{"name":"Дополнительно","specs":[{"description":"","filters":[{"id":15767999,"name":"Условия хранения"}],"isMainProperty":false,"name":"Условия хранения","value":"Хранить при температуре не выше 25°С.\u003Cbr\u003EХранить в недоступном для детей месте."},{"description":"","filters":[{"id":15768014,"name":"Передозировка"}],"isMainProperty":false,"name":"Передозировка","value":"При изучении острой токсичности метилпреднизолона ацепоната не было выявлено какого-либо риска острой интоксикации при чрезмерном однократном кожном применении (нанесении препарата на большую площадь при условиях, благоприятных для абсорбции) или непреднамеренном приеме внутрь.\u003Cbr\u003EПри чрезмерно долгом и/или интенсивном применении глюкокортикостероидов может развиться атрофия кожи (истончение кожи, телеангиэктазии, стрии).\u003Cbr\u003EПри появлении атрофии препарат необходимо отменить."},{"description":"","filters":[{"id":15768015,"name":"Применение при 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Ещё может подойти

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Инструкция

Показания к применению

Воспалительные заболевания кожи, чувствительные к терапии топическими глюкокортикостероидами:
атопический дерматит, нейродермит, детская экзема;
истинная экзема;
микробная экзема;
профессиональная экзема;
простой контактный дерматит;
аллергический (контактный) дерматит;
дисгидротическая экзема.

Противопоказания

Туберкулезный или сифилитический процессы в области нанесения препарата;
вирусные заболевания (например, ветряная оспа, опоясывающий лишай), в области нанесения препарата;
розацеа, периоральный дерматит в области нанесения препарата;
детский возраст до 4-х месяцев;
участки кожи с проявлениями реакции на вакцинацию;
гиперчувствительность к компонентам препарата.

Способ применения и дозы

Наружно. Взрослым и детям с 4-х месячного возраста. Препарат наносят 1 раз в сутки тонким слоем на пораженные участки кожи.
Как правило, длительность непрерывного ежедневного лечения Адвантаном не должна превышать 12 недель для взрослых и 4-х недель для детей.
При подостром или хроническом течении воспалительных заболеваний кожи, не сопровождающихся мокнутием, необходима лекарственная форма с уравновешенным соотношением жира и воды.
Мазь Адвантан оказывает лечебное действие, способствуя, также устранению сухости кожи и восстановлению её нормальной жирности.
Полная инструкция
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Адвантан мазь
Адвантан мазь, 0.1%, 15 мл, 15 г
4.9
(18)
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1 вопрос
Инструкция

Цена с картой Яндекс Пэй:830 ₽

Скидка: 2%
–2 %
Вместо: 846 ₽
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4.9
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У продавца:18 оценок·2 отзыва
У всех продавцов:154 оценки·46 отзывов
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user avatar
7 месяцев назад • Светлана Гейвандова • Куплен на Маркете
Достоинства: Помогает
Недостатки: Нет
Комментарий: Очень хорошо помог лечить кошку при дерматите
user avatar
7 месяцев назад • Алексе Илюхин • Куплен на Маркете
Достоинства: сразу помогло, и видно эффект
Посмотреть все отзывы на Маркете
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  • Комфодерм мазь д/нар. прим., 0.1%, 30 г
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    Комфодерм мазь д/нар. прим., 0.1%, 30 г

    Цена 758 ₽ вместо 766
  • Элидел крем д/нар. прим., 1%, 15 г
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    Элидел крем д/нар. прим., 1%, 15 г

    Цена 1 002 ₽
  • Адвантан эмульсия д/нар. прим., 0.1%, 20 г
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    Адвантан эмульсия д/нар. прим., 0.1%, 20 г

    Цена 717 ₽ вместо 724
  • Неотанин крем туба, 50 мл, 100 г
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    Неотанин крем туба, 50 мл, 100 г

    Цена 365 ₽ вместо 369
  • Жидкий пластырь Fixplast c пантенолом, 60 мл
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    Жидкий пластырь Fixplast c пантенолом, 60 мл

    Цена 355 ₽ вместо 399
  • Бепантен Плюс крем д/нар. прим., 5%+0.5%, 100 г
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    Бепантен Плюс крем д/нар. прим., 5%+0.5%, 100 г

    Цена 1 231 ₽ вместо 1 243
  • Реклама
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  • Комфодерм К крем д/нар. прим., 0.1%, 15 г
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    Комфодерм К крем д/нар. прим., 0.1%, 15 г

    Цена 558 ₽ вместо 594
  • Энтеросгель паста д/вн.приема, 22.5 г, 10 шт., нейтральный
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    Энтеросгель паста д/вн.приема, 22.5 г, 10 шт., нейтральный

    Цена 667 ₽ вместо 681
  • Бепантен крем д/нар. прим., 5%, 30 мл, 30 г
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    Бепантен крем д/нар. прим., 5%, 30 мл, 30 г

    Цена 616 ₽ вместо 622
  • Салфетка с нашатырем для стимуляции дыхания 3х6, 20 шт
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    Салфетка с нашатырем для стимуляции дыхания 3х6, 20 шт

    Цена 197 ₽ вместо 250
  • Акридерм мазь д/нар. прим., 0.05%, 15 г
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    Акридерм мазь д/нар. прим., 0.05%, 15 г

    Цена 103 ₽ вместо 104
  • Пимафукорт мазь д/нар. прим., 15 г
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    Пимафукорт мазь д/нар. прим., 15 г

    Цена 976 ₽ вместо 1 193
  • Полисорб МП пор. д/приг. сусп. д/вн. приема, 12 г
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    Полисорб МП пор. д/приг. сусп. д/вн. приема, 12 г

    Цена 319 ₽ вместо 322
  • Кето плюс шампунь, 150 мл, 1 шт.
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    Кето плюс шампунь, 150 мл, 1 шт.

    Цена 1 468 ₽ вместо 1 483
  • Argitos Коллоидное серебро спрей д/мест. прим. фл., 30 мл, 40 г, нейтральный
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    Argitos Коллоидное серебро спрей д/мест. прим. фл., 30 мл, 40 г, нейтральный

    Цена 365 ₽ вместо 395
  • Акридерм ГК мазь д/нар. прим., 15 г
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    Акридерм ГК мазь д/нар. прим., 15 г

    Цена 932 ₽ вместо 950
  • Целестодерм-В мазь, 0.1%, 30 г
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    Целестодерм-В мазь, 0.1%, 30 г

    Цена 343 ₽ вместо 393
  • Монтелукаст таб. п/о плен., 10 мг, 30 шт.
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    Монтелукаст таб. п/о плен., 10 мг, 30 шт.

    Цена 659 ₽ вместо 835
  • Реклама
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  • Тридерм крем, 15 г
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    Тридерм крем, 15 г

    Цена 1 070 ₽ вместо 1 081
  • Детралекс таб. п/о плен., 500 мг, 30 шт.
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    Детралекс таб. п/о плен., 500 мг, 30 шт.

    Цена 988 ₽ вместо 998
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