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Описание

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Аэртал таб. п/о плен., 100 мг, 20 шт.

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4.5
(10)
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Количество штук в упаковке, шт.: 20

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Коротко о товаре

Артикул Маркета
3176315327
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
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риносинусит, крапивница, полипы слизистой оболочки носа, бронхиальная астма);\u003Cbr\u003E— период после проведения аортокоронарного шунтирования;\u003Cbr\u003E— выраженная печеночная недостаточность или активное заболевание печени;\u003Cbr\u003E— нарушения кроветворения и коагуляции;\u003Cbr\u003E— выраженная почечная недостаточность, прогрессирующие заболевания почек;\u003Cbr\u003E— подтвержденная гиперкалиемия;\u003Cbr\u003E— беременность;\u003Cbr\u003E— период лактации (грудное вскармливание);\u003Cbr\u003E— детский и подростковый возраст до 18 лет;\u003Cbr\u003E— повышенная чувствительность к компонентам препарата."},{"name":"Состав","value":"Одна таблетка содержит:\u003Cbr\u003EДействующее вещество: ацеклофенак 100 мг.\u003Cbr\u003EВспомогательные вещества: целлюлоза микрокристаллическая 89,2 мг; повидон 6,6 мг; глицерил дистеарат, тип I 2,6 мг; кроскармеллоза натрия 6,6 мг.\u003Cbr\u003EСостав оболочки\u003Cbr\u003EСепифилм 752 белый 9 мг: гипромеллоза 40 %, целлюлоза микрокристаллическая 32 %, титана диоксид 20 %, макрогола стеарат, тип 18%."},{"name":"Действующее вещество","value":"Ацеклофенак","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["27144131:28709747"]}}},{"name":"Способ применения и дозы","value":"Внутрь. Таблетки следует проглатывать целиком, запивая достаточным количеством воды. Обычно взрослым назначают по 1 таблетке 100 мг 2 раза в день (одна таблетка утром и одна - вечером)."},{"name":"Побочные действия","value":"Ниже представлены нежелательные явления, информация о которых была получена в клинических исследованиях и в ходе постмаркетингового наблюдения. Нежелательные явления сгруппированы в соответствии с классами систем органов согласно MеdDRA и частотой возникновения: очень часто (≥1/10); часто (от ≥1/100 до \u003C1/10); нечасто (от ≥1/1000 до \u003C1/100), редко (от ≥1/10 000 до \u003C1/1000), очень редко (\u003C1/10 000).\u003Cbr\u003EСо стороны крови и лимфатической системы: редко - анемия; очень редко - угнетение функции костного мозга, гранулоцитопения, тромбоцитопения, нейтропения, гемолитическая анемия.\u003Cbr\u003EСо стороны иммунной системы: редко - анафилактические реакции (включая шок), гиперчувствительность.\u003Cbr\u003EСо стороны обмена веществ: очень редко - гиперкалиемия.\u003Cbr\u003EНарушения психики: очень редко - депрессия, необычные сновидения, бессонница.\u003Cbr\u003EСо стороны нервной системы: часто - головокружение; очень редко - парестезия, тремор, сонливость, головная боль, дисгевзия (извращение вкуса).\u003Cbr\u003EСо стороны органа зрения: редко - расстройство зрения.\u003Cbr\u003EСо стороны органа слуха и лабиринтные нарушения: очень редко - вертиго, шум в ушах.\u003Cbr\u003EСо стороны сердечно-сосудистой системы: редко - повышение АД, сердечная недостаточность; очень редко - учащенное сердцебиение, гиперемия кожи, \"приливы\", васкулит.\u003Cbr\u003EСо стороны дыхательной системы: редко - одышка; очень редко - бронхоспазм.\u003Cbr\u003EСо стороны пищеварительной системы: часто - диспепсия, боль в животе, тошнота, диарея; нечасто - метеоризм, гастрит, запор, рвота, изъязвление слизистой оболочки полости рта; редко - мелена, образование язв желудка и кишечника, геморрагическая диарея, желудочно-кишечное кровотечение; очень редко - стоматит, рвота кровью, прободение кишечника, обострение болезни Крона и язвенного колита, панкреатит.\u003Cbr\u003EСо стороны печени и желчевыводящих путей: часто - повышение активности ферментов печени; очень редко - заболевание печени (включая гепатит), повышение активности ЩФ.\u003Cbr\u003EСо стороны кожи и подкожных тканей: нечасто - зуд, сыпь, дерматит; очень редко - пурпура, экзема, тяжелые реакции со стороны кожи и слизистых оболочек (включая синдром Стивенса-Джонсона и токсический эпидермальный некролиз). В отдельных случаях наблюдались серьезные кожные инфекции и инфекции мягких тканей при приеме НПВП во время заболевания ветряной оспой.\u003Cbr\u003EАллергические реакции: нечасто - крапивница; редко - ангионевротический отек.\u003Cbr\u003EСо стороны мочевыделительной системы: нечасто - повышение концентрации мочевины сыворотки крови, повышение концентрации креатинина сыворотки крови; очень редко - нефротический синдром, почечная недостаточность, интерстициальный нефрит.\u003Cbr\u003EОбщие реакции: очень редко - отек, повышенная утомляемость, спазм мышц нижних конечностей.\u003Cbr\u003EДанные лабораторных исследований: очень редко - увеличение массы тела.\u003Cbr\u003EЕсли любые из указанных выше побочных эффектов усугубляются или появляются любые другие побочные эффекты, пациенту следует сообщить об этом врачу."},{"name":"Фармакологическое действие","value":"Ацеклофенак обладает противовоспалительным, обезболивающим и жаропонижающим действием. Угнетает синтез простагландинов и, таким образом, влияет на патогенез воспаления, возникновения боли и лихорадки. При ревматических заболеваниях противовоспалительное и анальгезирующее действие ацеклофенака способствует значительному уменьшению выраженности боли, утренней скованности, припухлости суставов, что улучшает функциональное состояние пациента."},{"name":"Фармакологическая группа","value":"нестероидный противовоспалительный препарат (НПВП)"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"Препарат следует хранить в недоступном для детей месте при температуре не выше 25°С."},{"name":"Передозировка","value":"Нет данных о передозировке ацеклофенака у человека.\u003Cbr\u003EСимптомы: возможно тошнота, рвота, боль в области желудка, головокружение, головная боль, явления гипервентиляции с повышенной судорожной готовностью.\u003Cbr\u003EЛечение: промывание желудка, прием внутрь активированного угля, симптоматическая терапия. Форсированный диурез, гемодиализ малоэффективны."},{"name":"Применение при беременности и кормлении грудью","value":"Беременность\u003Cbr\u003EАэртал, таблетки, покрытые пленочной оболочкой, 100 мг противопоказан при беременности. Информация о применении ацеклофенака при беременности отсутствует. Угнетение синтеза простагландинов может неблагоприятно влиять на течение беременности и/или развитие эмбриона/плода.\u003Cbr\u003EВ течение третьего триместра беременности все ингибиторы синтеза простагландинов:\u003Cbr\u003E- обладая сердечно-легочной токсичностью, могут вызывать преждевременное закрытие Боталлова протока с развитием легочной гипертензии;\u003Cbr\u003E- могут вызывать нарушение функции почек плода, которое может прогрессировать до почечной недостаточности в сочетании с многоводием.\u003Cbr\u003EМатери и новорожденные на поздних сроках беременности:\u003Cbr\u003Eпрепарат может влиять на продолжительность кровотечения из-за антиагрегантного эффекта, который может развиться даже после применения очень низких доз;\u003Cbr\u003E- препарат может подавлять сокращения матки, приводя к задержке родов или к затяжным родам.\u003Cbr\u003EЛактация\u003Cbr\u003EАэртал®, таблетки покрытые пленочной оболочкой, 100 мг не следует принимать во время кормления грудью. Данные о выделении ацеклофенака с женским молоком отсутствуют; при назначении радиоактивного 14С-ацеклофенака лактирующим крысам заметного переноса радиоактивности в молоко не наблюдалось.\u003Cbr\u003EФертильность\u003Cbr\u003EНестероидные противовоспалительные препараты (НПВП) могут влиять на фертильность и не рекомендуются к применению женщинами, планирующими беременность."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Следует воздержаться от управления транспортными средствами и занятий другими потенциально опасными видами деятельности, требующими повышенной концентраци нимания и быстроты психомоторных реакций, т.к. препарат способен вызывать головокружение и другие побочные эффекты, которые могут влиять на указанные способности."},{"name":"Особые указания","value":"Следует избегать одновременного приема препарата Аэртал и других НПВП, включая селективные ингибиторы ЦОГ-2.\u003Cbr\u003EНежелательные явления могут быть минимизированы путем применения наименьшей эффективной дозы и уменьшения продолжительности лечения, необходимого для контроля симптомов.\u003Cbr\u003EВлияние на ЖКТ\u003Cbr\u003EКровотечение, язва или прободение ЖКТ с летальным исходом наблюдались при приеме любых НПВП в любой период лечения, как при наличии соответствующих симптомов и наличии серьезных заболеваний ЖКТ в анамнезе (в т.ч. язвенная болезнь желудка и двенадцатиперстной кишки, болезнь Крона, язвенный колит), так и без них.\u003Cbr\u003EРиск кровотечения, образования язвы и прободения ЖКТ возрастает с увеличением дозы НПВП у пациентов с язвенной болезнью в анамнезе, особенно если она сопровождалась кровотечением или прободением, а также у пациентов пожилого возраста. Этим пациентам следует принимать минимальную эффективную дозу препарата. Им необходима комбинированная терапия с применением препаратов-протекторов (например, мизопростол или ингибиторы протоновой помпы). Такое лечение необходимо пациентам, принимающим небольшие дозы аспирина или других препаратов, которые негативно влияют на состояние ЖКТ.\u003Cbr\u003EПациенты с заболеваниями ЖКТ, включая пациентов пожилого возраста, должны сообщать о любых необычных симптомах, связанных с ЖКТ (особенно кровотечение), в т.ч. при первичном приеме препарата. Особая осторожность требуется при назначении препарата пациентам, одновременно принимающим препараты, которые могут повышать риск возникновения кровотечения или язвы, такие как системные ГКС, антикоагулянты (такие как варфарин), селективные ингибиторы обратного захвата серотонина или антиагреганты (такие как ацетилсалициловая кислота).\u003Cbr\u003EПри возникновении желудочно-кишечного кровотечения или язвы у пациентов, принимающих Аэртал®, лечение следует отменить.\u003Cbr\u003EВлияние на сердечно-сосудистую систему и ЦНС\u003Cbr\u003EПациентам с артериальной гипертензией и/или застойной сердечной недостаточностью легкой или умеренной степени требуется соответствующее наблюдение, т.к. с приемом НПВП ассоциированы задержка жидкости в организме и отеки.\u003Cbr\u003EКлинические исследования и эпидемиологические данные показывают, что применение некоторых НПВП (в частности, в высоких дозах и при длительном применении) может несущественно увеличивать риск артериального тромбоза (например, инфаркта миокарда или инсульта). Нет достоверных данных об отсутствии этого риска при приеме ацеклофенака.\u003Cbr\u003EПациентам с неконтролируемой артериальной гипертензией, хронической сердечной недостаточностью, установленной ИБС, атеросклерозом периферических артерий и/или нарушением мозгового кровообращения следует соблюдать особую осторожность при приеме ацеклофенака. Также, перед первым приемом следует соблюдать осторожность пациентам с факторами риска для сердечно-сосудистой системы (например, артериальная гипертензия, гиперлипидемия, сахарный диабет и курение).\u003Cbr\u003EВлияние на печень и почки\u003Cbr\u003EПрием НПВП может вызвать дозозависимое снижение образования простагландинов и острую почечную недостаточность. Важность простагландинов для обеспечения почечного кровотока следует учитывать при приеме препарата у пациентов с нарушением функции сердца, почек или печени, у пациентов, получающих диуретики, или у пациентов после хирургического вмешательства, а также у пожилых.\u003Cbr\u003EСледует соблюдать осторожность при назначении препарата пациентам с нарушениями функции печени и почек легкой или умеренной степени, а также пациентам с другими состояниями, предрасполагающими к задержке жидкости в организме. У этих пациентов НПВП могут привести к нарушению функции почек и к задержке жидкости. Пациентам, принимающим диуретики, лицам с повышенным риском гиповолемии также следует соблюдать осторожность при приеме препарата Аэртал®. Необходимо назначение минимальной эффективной дозы и регулярный врачебный контроль за функцией почек. Нежелательные явления со стороны почек обычно разрешаются после прекращения приема ацеклофенака.\u003Cbr\u003EПрием ацеклофенака следует прекратить, если изменения показателей функции печени сохраняются или ухудшаются, развиваются клинические признаки или симптомы заболеваний печени, либо возникают другие проявления (эозинофилия, сыпь). Гепатит может развиться без продромальных симптомов.\u003Cbr\u003EПрименение НПВП у пациентов с печеночной порфирией может спровоцировать приступ.\u003Cbr\u003EГиперчувствительность и кожные реакции\u003Cbr\u003EКак и другие НПВП, препарат может вызывать аллергические реакции, включая анафилактические/анафилактоидные реакции, даже если препарат принимается впервые. Тяжелые кожные реакции (некоторые из которых могут привести к летальному исходу), включая эксфолиативный дерматит, синдром Стивенса-Джонсона и токсический эпидермальный некролиз, после приема НПВП наблюдались очень редко. Самый высокий риск возникновения этих реакций у пациентов наблюдается в начале приема препарата, также развитие данных нежелательных реакций наблюдается в течение первого месяца приема препарата. При возникновении кожной сыпи, повреждений слизистой оболочки полости рта или других признаков гиперчувствительности следует прекратить прием ацеклофенака.\u003Cbr\u003EВ отдельных случаях при ветряной оспе могут возникнуть инфекции кожи и мягких тканей.\u003Cbr\u003EВ настоящее время нельзя исключать роль НПВП в ухудшении течения этих инфекций. Поэтому следует избегать приема препарата Аэртал® при ветряной оспе.\u003Cbr\u003EГематологические нарушения\u003Cbr\u003EАцеклофенак может вызывать обратимое угнетение агрегации тромбоцитов.\u003Cbr\u003EНарушения со стороны дыхательной системы\u003Cbr\u003EСледует соблюдать осторожность при приеме препарата у пациентов с бронхиальной астмой в анамнезе или текущей, так как прием НПВП может спровоцировать развитие внезапного бронхоспазма у таких пациентов.\u003Cbr\u003EПациенты пожилого возраста\u003Cbr\u003EСледует соблюдать осторожность при приеме препарата у пациентов пожилого возраста, т.к. у них чаще возникают побочные явления (особенно кровотечение и прободение ЖКТ) при приеме НПВП. Осложнения могут привести к летальному исходу. Также пожилые пациенты чаще страдают заболеваниями почек, печени или сердечно сосудистой системы.\u003Cbr\u003EДлительное применение\u003Cbr\u003EВсе пациенты, получающие длительное лечение НПВП, должны находиться под тщательным наблюдением (например, общий анализ крови, функциональные печеночные и почечные тесты).\u003Cbr\u003EС осторожностью следует применять препарат при заболеваниях печени, почек и ЖКТ в анамнезе, бронхиальной астме, артериальной гипертензии, снижении ОЦК (в т.ч. сразу после обширных оперативных вмешательств), ИБС, хронической почечной, печеночной и сердечной недостаточности, при КК\u003C60 мл/мин, указаниях в анамнезе на развитие язвенного поражения ЖКТ, наличии инфекции Helicobacter pylori, при цереброваскулярных заболеваниях, дислипидемии/гиперлипидемии, сахарном диабете, заболеваниях периферических артерий, у курящих, у пациентов пожилого возраста, при длительном приеме НПВС, при частом употреблении алкоголя, при тяжелых соматических заболеваниях."},{"name":"Взаимодействие","value":"За исключением варфарина, исследований лекарственного взаимодействия не проводилось.\u003Cbr\u003EАцеклофенак метаболизируется при участии изофермента CYP2C9; данные in vitro показывают, что ацеклофенак может быть ингибитором этого фермента. Таким образом, риск фармакокинетического взаимодействия возможен при одновременном приеме с фенитоином, циметидином, толбутамидом, фенилбутазоном, амиодароном, миконазолом и сульфафеназолом. Как и в случае с другими НПВП, увеличивается риск фармакокинетического взаимодействия с другими препаратами, которые выводятся из организма путем активной почечной секреции, такими как метотрексат и препараты лития. Ацеклофенак практически полностью связывается с альбумином плазмы крови и, следовательно, есть возможность взаимодействия по типу вытеснения с другими препаратами, связывающимися с белками. Ниже приведена класс-специфичная информация для НПВП.\u003Cbr\u003EНПВП ингибируют канальцевую секрецию метотрексата; более того, может наблюдаться небольшое метаболическое взаимодействие, что приводит к уменьшению клиренса метотрексата. Поэтому при применении метотрексата в высоких дозах следует избегать назначения НПВП.\u003Cbr\u003EНекоторые НПВП ингибируют почечный клиренс лития и дигоксина, что приводит к увеличению концентрации в сыворотке обоих веществ. Следует избегать совместного применения, если не проводится частый контроль концентраций лития и дигоксина.\u003Cbr\u003EНПВП ингибируют агрегацию тромбоцитов и повреждают слизистую оболочку ЖКТ, что может привести к усилению действия антикоагулянтов и увеличить риск желудочно-кишечного кровотечения на фоне приема антикоагулянтов. Следует избегать совместного применения ацеклофенака и пероральных антикоагулянтов кумариновой группы, тиклопидина и тромболитиков, если не проводится тщательное наблюдение за состоянием пациента.\u003Cbr\u003EПри совместном применении с селективными ингибиторами обратного захвата серотонина НПВП способны увеличивать риск желудочно-кишечного кровотечения.\u003Cbr\u003EПри одновременном приеме НПВП с циклоспорином или такролимусом следует учитывать риск повышенной нефротоксичности из-за снижения образования почечного простациклина. Поэтому при одновременном приеме следует тщательно контролировать показатели функции почек\u003Cbr\u003EПри одновременном приеме ацетилсалициловой кислоты или других НПВП возможно увеличение частоты возникновения побочных явлений, поэтому следует при таких комбинациях требуется осторожность.\u003Cbr\u003EПри одновременном применении с ГКС возрастает риск возникновения язвы или желудочно-кишечного кровотечения.\u003Cbr\u003EАцеклофенак, как и другие НПВП, способен ингибировать активность диуретиков, может уменьшать диуретический эффект фуросемида и буметанида и антигипертензивный эффект тиазидов. Совместный прием с калийсберегающими диуретиками может привести к увеличению содержания калия в сыворотке крови. Ацеклофенак не влиял на контроль АД при совместном применении с бендрофлуазидом, хотя нельзя исключить взаимодействие с другими диуретиками.\u003Cbr\u003EНПВП могут также уменьшать эффект гипотензивных препаратов. Совместный прием ингибиторов АПФ или антагонистов рецепторов ангиотензина II и НПВП может привести к нарушению функции почек. Риск возникновения острой почечной недостаточности, которая обычно носит обратимый характер, может возрастать у некоторых пациентов с нарушениями функции почек, например, у пожилых или при обезвоживании. Поэтому при совместном применении с НПВП следует соблюдать осторожность. Пациенты должны потреблять необходимое количество жидкости и находиться под соответствующим наблюдением (контроль функции почек в начале совместного применения и периодически в ходе лечения).\u003Cbr\u003EКлинические исследования показывают, что диклофенак может применяться совместно с пероральными гипогликемическими средствами без влияния на их клинический эффект. Однако имеются отдельные сообщения о гипогликемических и гипергликемических эффектах препарата. Таким образом, при приеме ацеклофенака следует провести коррекцию доз препаратов, которые могут вызвать гипогликемию.\u003Cbr\u003EПри одновременном приеме НПВП и зидовудина возрастает риск гематологической токсичности. Имеются данные об увеличении риска возникновения гемартрозов и гематом у ВИЧ-положительных пациентов с гемофилией, получающих зидовудин и ибупрофен."},{"name":"Регистрационный номер","value":"П N013504/01"},{"name":"Дата государственной регистрации","value":"20.05.2021"},{"name":"Владелец регистрационного удостоверения","value":"Almirall","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["34324371:35649313","7893318:16003820"]}}},{"name":"Изготовитель","value":"Гедеон Рихтер"},{"name":"Фасовщик","value":"Гедеон Рихтер"},{"name":"Страна бренда","value":"Испания"},{"name":"Страна-производитель","value":"Венгрия"},{"name":"Название препарата","value":"Аэртал","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["17796364:18025561"]}}},{"name":"Срок годности","value":"36 мес."}]}},"fullSpecsGrouped":{"9707658781895020069":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"опорно-двигательная система, половая система, ротовая полость"},{"name":"Назначение","value":"анкилозирующий спондилит, боль в суставах, зубная боль, люмбаго, менструальные боли, остеоартроз, периартрит, ревматоидный артрит"},{"name":"Показания к применению","value":"Купирование воспаления и болевого синдрома при:\u003Cbr\u003E— люмбаго;\u003Cbr\u003E— зубной боли;\u003Cbr\u003E— плечелопаточном периартрите;\u003Cbr\u003E— ревматическом поражении мягких тканей.\u003Cbr\u003EСимптоматическое лечение:\u003Cbr\u003E— ревматоидного артрита;\u003Cbr\u003E— остеоартроза;\u003Cbr\u003E— анкилозирующего спондилита."},{"name":"Противопоказания","value":"Эрозивно-язвенные поражения ЖКТ в фазе обострения;\u003Cbr\u003E— желудочно-кишечное кровотечение или подозрение на него;\u003Cbr\u003E— указания в анамнезе на бронхоспазм, крапивницу, ринит после приема ацетилсалициловой кислоты или других НПВС (полный или неполный синдром непереносимости ацетилсалициловой кислоты - риносинусит, крапивница, полипы слизистой оболочки носа, бронхиальная астма);\u003Cbr\u003E— период после проведения аортокоронарного шунтирования;\u003Cbr\u003E— выраженная печеночная недостаточность или активное заболевание печени;\u003Cbr\u003E— нарушения кроветворения и коагуляции;\u003Cbr\u003E— выраженная почечная недостаточность, прогрессирующие заболевания почек;\u003Cbr\u003E— подтвержденная гиперкалиемия;\u003Cbr\u003E— беременность;\u003Cbr\u003E— период лактации (грудное вскармливание);\u003Cbr\u003E— детский и подростковый возраст до 18 лет;\u003Cbr\u003E— повышенная чувствительность к компонентам препарата."},{"name":"Состав","value":"Одна таблетка содержит:\u003Cbr\u003EДействующее вещество: ацеклофенак 100 мг.\u003Cbr\u003EВспомогательные вещества: целлюлоза микрокристаллическая 89,2 мг; повидон 6,6 мг; глицерил дистеарат, тип I 2,6 мг; кроскармеллоза натрия 6,6 мг.\u003Cbr\u003EСостав оболочки\u003Cbr\u003EСепифилм 752 белый 9 мг: гипромеллоза 40 %, целлюлоза микрокристаллическая 32 %, титана диоксид 20 %, макрогола стеарат, тип 18%."},{"name":"Действующее вещество","value":"Ацеклофенак"},{"name":"Способ применения и дозы","value":"Внутрь. Таблетки следует проглатывать целиком, запивая достаточным количеством воды. Обычно взрослым назначают по 1 таблетке 100 мг 2 раза в день (одна таблетка утром и одна - вечером)."},{"name":"Побочные действия","value":"Ниже представлены нежелательные явления, информация о которых была получена в клинических исследованиях и в ходе постмаркетингового наблюдения. Нежелательные явления сгруппированы в соответствии с классами систем органов согласно MеdDRA и частотой возникновения: очень часто (≥1/10); часто (от ≥1/100 до \u003C1/10); нечасто (от ≥1/1000 до \u003C1/100), редко (от ≥1/10 000 до \u003C1/1000), очень редко (\u003C1/10 000).\u003Cbr\u003EСо стороны крови и лимфатической системы: редко - анемия; очень редко - угнетение функции костного мозга, гранулоцитопения, тромбоцитопения, нейтропения, гемолитическая анемия.\u003Cbr\u003EСо стороны иммунной системы: редко - анафилактические реакции (включая шок), гиперчувствительность.\u003Cbr\u003EСо стороны обмена веществ: очень редко - гиперкалиемия.\u003Cbr\u003EНарушения психики: очень редко - депрессия, необычные сновидения, бессонница.\u003Cbr\u003EСо стороны нервной системы: часто - головокружение; очень редко - парестезия, тремор, сонливость, головная боль, дисгевзия (извращение вкуса).\u003Cbr\u003EСо стороны органа зрения: редко - расстройство зрения.\u003Cbr\u003EСо стороны органа слуха и лабиринтные нарушения: очень редко - вертиго, шум в ушах.\u003Cbr\u003EСо стороны сердечно-сосудистой системы: редко - повышение АД, сердечная недостаточность; очень редко - учащенное сердцебиение, гиперемия кожи, \"приливы\", васкулит.\u003Cbr\u003EСо стороны дыхательной системы: редко - одышка; очень редко - бронхоспазм.\u003Cbr\u003EСо стороны пищеварительной системы: часто - диспепсия, боль в животе, тошнота, диарея; нечасто - метеоризм, гастрит, запор, рвота, изъязвление слизистой оболочки полости рта; редко - мелена, образование язв желудка и кишечника, геморрагическая диарея, желудочно-кишечное кровотечение; очень редко - стоматит, рвота кровью, прободение кишечника, обострение болезни Крона и язвенного колита, панкреатит.\u003Cbr\u003EСо стороны печени и желчевыводящих путей: часто - повышение активности ферментов печени; очень редко - заболевание печени (включая гепатит), повышение активности ЩФ.\u003Cbr\u003EСо стороны кожи и подкожных тканей: нечасто - зуд, сыпь, дерматит; очень редко - пурпура, экзема, тяжелые реакции со стороны кожи и слизистых оболочек (включая синдром Стивенса-Джонсона и токсический эпидермальный некролиз). В отдельных случаях наблюдались серьезные кожные инфекции и инфекции мягких тканей при приеме НПВП во время заболевания ветряной оспой.\u003Cbr\u003EАллергические реакции: нечасто - крапивница; редко - ангионевротический отек.\u003Cbr\u003EСо стороны мочевыделительной системы: нечасто - повышение концентрации мочевины сыворотки крови, повышение концентрации креатинина сыворотки крови; очень редко - нефротический синдром, почечная недостаточность, интерстициальный нефрит.\u003Cbr\u003EОбщие реакции: очень редко - отек, повышенная утомляемость, спазм мышц нижних конечностей.\u003Cbr\u003EДанные лабораторных исследований: очень редко - увеличение массы тела.\u003Cbr\u003EЕсли любые из указанных выше побочных эффектов усугубляются или появляются любые другие побочные эффекты, пациенту следует сообщить об этом врачу."},{"name":"Фармакологическое действие","value":"Ацеклофенак обладает противовоспалительным, обезболивающим и жаропонижающим действием. Угнетает синтез простагландинов и, таким образом, влияет на патогенез воспаления, возникновения боли и лихорадки. При ревматических заболеваниях противовоспалительное и анальгезирующее действие ацеклофенака способствует значительному уменьшению выраженности боли, утренней скованности, припухлости суставов, что улучшает функциональное состояние пациента."},{"name":"Фармакологическая группа","value":"нестероидный противовоспалительный препарат (НПВП)"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"Препарат следует хранить в недоступном для детей месте при температуре не выше 25°С."},{"name":"Передозировка","value":"Нет данных о передозировке ацеклофенака у человека.\u003Cbr\u003EСимптомы: возможно тошнота, рвота, боль в области желудка, головокружение, головная боль, явления гипервентиляции с повышенной судорожной готовностью.\u003Cbr\u003EЛечение: промывание желудка, прием внутрь активированного угля, симптоматическая терапия. Форсированный диурез, гемодиализ малоэффективны."},{"name":"Применение при беременности и кормлении грудью","value":"Беременность\u003Cbr\u003EАэртал, таблетки, покрытые пленочной оболочкой, 100 мг противопоказан при беременности. Информация о применении ацеклофенака при беременности отсутствует. Угнетение синтеза простагландинов может неблагоприятно влиять на течение беременности и/или развитие эмбриона/плода.\u003Cbr\u003EВ течение третьего триместра беременности все ингибиторы синтеза простагландинов:\u003Cbr\u003E- обладая сердечно-легочной токсичностью, могут вызывать преждевременное закрытие Боталлова протока с развитием легочной гипертензии;\u003Cbr\u003E- могут вызывать нарушение функции почек плода, которое может прогрессировать до почечной недостаточности в сочетании с многоводием.\u003Cbr\u003EМатери и новорожденные на поздних сроках беременности:\u003Cbr\u003Eпрепарат может влиять на продолжительность кровотечения из-за антиагрегантного эффекта, который может развиться даже после применения очень низких доз;\u003Cbr\u003E- препарат может подавлять сокращения матки, приводя к задержке родов или к затяжным родам.\u003Cbr\u003EЛактация\u003Cbr\u003EАэртал®, таблетки покрытые пленочной оболочкой, 100 мг не следует принимать во время кормления грудью. Данные о выделении ацеклофенака с женским молоком отсутствуют; при назначении радиоактивного 14С-ацеклофенака лактирующим крысам заметного переноса радиоактивности в молоко не наблюдалось.\u003Cbr\u003EФертильность\u003Cbr\u003EНестероидные противовоспалительные препараты (НПВП) могут влиять на фертильность и не рекомендуются к применению женщинами, планирующими беременность."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Следует воздержаться от управления транспортными средствами и занятий другими потенциально опасными видами деятельности, требующими повышенной концентраци нимания и быстроты психомоторных реакций, т.к. препарат способен вызывать головокружение и другие побочные эффекты, которые могут влиять на указанные способности."},{"name":"Особые указания","value":"Следует избегать одновременного приема препарата Аэртал и других НПВП, включая селективные ингибиторы ЦОГ-2.\u003Cbr\u003EНежелательные явления могут быть минимизированы путем применения наименьшей эффективной дозы и уменьшения продолжительности лечения, необходимого для контроля симптомов.\u003Cbr\u003EВлияние на ЖКТ\u003Cbr\u003EКровотечение, язва или прободение ЖКТ с летальным исходом наблюдались при приеме любых НПВП в любой период лечения, как при наличии соответствующих симптомов и наличии серьезных заболеваний ЖКТ в анамнезе (в т.ч. язвенная болезнь желудка и двенадцатиперстной кишки, болезнь Крона, язвенный колит), так и без них.\u003Cbr\u003EРиск кровотечения, образования язвы и прободения ЖКТ возрастает с увеличением дозы НПВП у пациентов с язвенной болезнью в анамнезе, особенно если она сопровождалась кровотечением или прободением, а также у пациентов пожилого возраста. Этим пациентам следует принимать минимальную эффективную дозу препарата. Им необходима комбинированная терапия с применением препаратов-протекторов (например, мизопростол или ингибиторы протоновой помпы). Такое лечение необходимо пациентам, принимающим небольшие дозы аспирина или других препаратов, которые негативно влияют на состояние ЖКТ.\u003Cbr\u003EПациенты с заболеваниями ЖКТ, включая пациентов пожилого возраста, должны сообщать о любых необычных симптомах, связанных с ЖКТ (особенно кровотечение), в т.ч. при первичном приеме препарата. Особая осторожность требуется при назначении препарата пациентам, одновременно принимающим препараты, которые могут повышать риск возникновения кровотечения или язвы, такие как системные ГКС, антикоагулянты (такие как варфарин), селективные ингибиторы обратного захвата серотонина или антиагреганты (такие как ацетилсалициловая кислота).\u003Cbr\u003EПри возникновении желудочно-кишечного кровотечения или язвы у пациентов, принимающих Аэртал®, лечение следует отменить.\u003Cbr\u003EВлияние на сердечно-сосудистую систему и ЦНС\u003Cbr\u003EПациентам с артериальной гипертензией и/или застойной сердечной недостаточностью легкой или умеренной степени требуется соответствующее наблюдение, т.к. с приемом НПВП ассоциированы задержка жидкости в организме и отеки.\u003Cbr\u003EКлинические исследования и эпидемиологические данные показывают, что применение некоторых НПВП (в частности, в высоких дозах и при длительном применении) может несущественно увеличивать риск артериального тромбоза (например, инфаркта миокарда или инсульта). Нет достоверных данных об отсутствии этого риска при приеме ацеклофенака.\u003Cbr\u003EПациентам с неконтролируемой артериальной гипертензией, хронической сердечной недостаточностью, установленной ИБС, атеросклерозом периферических артерий и/или нарушением мозгового кровообращения следует соблюдать особую осторожность при приеме ацеклофенака. Также, перед первым приемом следует соблюдать осторожность пациентам с факторами риска для сердечно-сосудистой системы (например, артериальная гипертензия, гиперлипидемия, сахарный диабет и курение).\u003Cbr\u003EВлияние на печень и почки\u003Cbr\u003EПрием НПВП может вызвать дозозависимое снижение образования простагландинов и острую почечную недостаточность. Важность простагландинов для обеспечения почечного кровотока следует учитывать при приеме препарата у пациентов с нарушением функции сердца, почек или печени, у пациентов, получающих диуретики, или у пациентов после хирургического вмешательства, а также у пожилых.\u003Cbr\u003EСледует соблюдать осторожность при назначении препарата пациентам с нарушениями функции печени и почек легкой или умеренной степени, а также пациентам с другими состояниями, предрасполагающими к задержке жидкости в организме. У этих пациентов НПВП могут привести к нарушению функции почек и к задержке жидкости. Пациентам, принимающим диуретики, лицам с повышенным риском гиповолемии также следует соблюдать осторожность при приеме препарата Аэртал®. Необходимо назначение минимальной эффективной дозы и регулярный врачебный контроль за функцией почек. Нежелательные явления со стороны почек обычно разрешаются после прекращения приема ацеклофенака.\u003Cbr\u003EПрием ацеклофенака следует прекратить, если изменения показателей функции печени сохраняются или ухудшаются, развиваются клинические признаки или симптомы заболеваний печени, либо возникают другие проявления (эозинофилия, сыпь). Гепатит может развиться без продромальных симптомов.\u003Cbr\u003EПрименение НПВП у пациентов с печеночной порфирией может спровоцировать приступ.\u003Cbr\u003EГиперчувствительность и кожные реакции\u003Cbr\u003EКак и другие НПВП, препарат может вызывать аллергические реакции, включая анафилактические/анафилактоидные реакции, даже если препарат принимается впервые. Тяжелые кожные реакции (некоторые из которых могут привести к летальному исходу), включая эксфолиативный дерматит, синдром Стивенса-Джонсона и токсический эпидермальный некролиз, после приема НПВП наблюдались очень редко. Самый высокий риск возникновения этих реакций у пациентов наблюдается в начале приема препарата, также развитие данных нежелательных реакций наблюдается в течение первого месяца приема препарата. При возникновении кожной сыпи, повреждений слизистой оболочки полости рта или других признаков гиперчувствительности следует прекратить прием ацеклофенака.\u003Cbr\u003EВ отдельных случаях при ветряной оспе могут возникнуть инфекции кожи и мягких тканей.\u003Cbr\u003EВ настоящее время нельзя исключать роль НПВП в ухудшении течения этих инфекций. Поэтому следует избегать приема препарата Аэртал® при ветряной оспе.\u003Cbr\u003EГематологические нарушения\u003Cbr\u003EАцеклофенак может вызывать обратимое угнетение агрегации тромбоцитов.\u003Cbr\u003EНарушения со стороны дыхательной системы\u003Cbr\u003EСледует соблюдать осторожность при приеме препарата у пациентов с бронхиальной астмой в анамнезе или текущей, так как прием НПВП может спровоцировать развитие внезапного бронхоспазма у таких пациентов.\u003Cbr\u003EПациенты пожилого возраста\u003Cbr\u003EСледует соблюдать осторожность при приеме препарата у пациентов пожилого возраста, т.к. у них чаще возникают побочные явления (особенно кровотечение и прободение ЖКТ) при приеме НПВП. Осложнения могут привести к летальному исходу. Также пожилые пациенты чаще страдают заболеваниями почек, печени или сердечно сосудистой системы.\u003Cbr\u003EДлительное применение\u003Cbr\u003EВсе пациенты, получающие длительное лечение НПВП, должны находиться под тщательным наблюдением (например, общий анализ крови, функциональные печеночные и почечные тесты).\u003Cbr\u003EС осторожностью следует применять препарат при заболеваниях печени, почек и ЖКТ в анамнезе, бронхиальной астме, артериальной гипертензии, снижении ОЦК (в т.ч. сразу после обширных оперативных вмешательств), ИБС, хронической почечной, печеночной и сердечной недостаточности, при КК\u003C60 мл/мин, указаниях в анамнезе на развитие язвенного поражения ЖКТ, наличии инфекции Helicobacter pylori, при цереброваскулярных заболеваниях, дислипидемии/гиперлипидемии, сахарном диабете, заболеваниях периферических артерий, у курящих, у пациентов пожилого возраста, при длительном приеме НПВС, при частом употреблении алкоголя, при тяжелых соматических заболеваниях."},{"name":"Взаимодействие","value":"За исключением варфарина, исследований лекарственного взаимодействия не проводилось.\u003Cbr\u003EАцеклофенак метаболизируется при участии изофермента CYP2C9; данные in vitro показывают, что ацеклофенак может быть ингибитором этого фермента. Таким образом, риск фармакокинетического взаимодействия возможен при одновременном приеме с фенитоином, циметидином, толбутамидом, фенилбутазоном, амиодароном, миконазолом и сульфафеназолом. Как и в случае с другими НПВП, увеличивается риск фармакокинетического взаимодействия с другими препаратами, которые выводятся из организма путем активной почечной секреции, такими как метотрексат и препараты лития. Ацеклофенак практически полностью связывается с альбумином плазмы крови и, следовательно, есть возможность взаимодействия по типу вытеснения с другими препаратами, связывающимися с белками. Ниже приведена класс-специфичная информация для НПВП.\u003Cbr\u003EНПВП ингибируют канальцевую секрецию метотрексата; более того, может наблюдаться небольшое метаболическое взаимодействие, что приводит к уменьшению клиренса метотрексата. Поэтому при применении метотрексата в высоких дозах следует избегать назначения НПВП.\u003Cbr\u003EНекоторые НПВП ингибируют почечный клиренс лития и дигоксина, что приводит к увеличению концентрации в сыворотке обоих веществ. Следует избегать совместного применения, если не проводится частый контроль концентраций лития и дигоксина.\u003Cbr\u003EНПВП ингибируют агрегацию тромбоцитов и повреждают слизистую оболочку ЖКТ, что может привести к усилению действия антикоагулянтов и увеличить риск желудочно-кишечного кровотечения на фоне приема антикоагулянтов. Следует избегать совместного применения ацеклофенака и пероральных антикоагулянтов кумариновой группы, тиклопидина и тромболитиков, если не проводится тщательное наблюдение за состоянием пациента.\u003Cbr\u003EПри совместном применении с селективными ингибиторами обратного захвата серотонина НПВП способны увеличивать риск желудочно-кишечного кровотечения.\u003Cbr\u003EПри одновременном приеме НПВП с циклоспорином или такролимусом следует учитывать риск повышенной нефротоксичности из-за снижения образования почечного простациклина. Поэтому при одновременном приеме следует тщательно контролировать показатели функции почек\u003Cbr\u003EПри одновременном приеме ацетилсалициловой кислоты или других НПВП возможно увеличение частоты возникновения побочных явлений, поэтому следует при таких комбинациях требуется осторожность.\u003Cbr\u003EПри одновременном применении с ГКС возрастает риск возникновения язвы или желудочно-кишечного кровотечения.\u003Cbr\u003EАцеклофенак, как и другие НПВП, способен ингибировать активность диуретиков, может уменьшать диуретический эффект фуросемида и буметанида и антигипертензивный эффект тиазидов. Совместный прием с калийсберегающими диуретиками может привести к увеличению содержания калия в сыворотке крови. Ацеклофенак не влиял на контроль АД при совместном применении с бендрофлуазидом, хотя нельзя исключить взаимодействие с другими диуретиками.\u003Cbr\u003EНПВП могут также уменьшать эффект гипотензивных препаратов. Совместный прием ингибиторов АПФ или антагонистов рецепторов ангиотензина II и НПВП может привести к нарушению функции почек. Риск возникновения острой почечной недостаточности, которая обычно носит обратимый характер, может возрастать у некоторых пациентов с нарушениями функции почек, например, у пожилых или при обезвоживании. Поэтому при совместном применении с НПВП следует соблюдать осторожность. Пациенты должны потреблять необходимое количество жидкости и находиться под соответствующим наблюдением (контроль функции почек в начале совместного применения и периодически в ходе лечения).\u003Cbr\u003EКлинические исследования показывают, что диклофенак может применяться совместно с пероральными гипогликемическими средствами без влияния на их клинический эффект. Однако имеются отдельные сообщения о гипогликемических и гипергликемических эффектах препарата. Таким образом, при приеме ацеклофенака следует провести коррекцию доз препаратов, которые могут вызвать гипогликемию.\u003Cbr\u003EПри одновременном приеме НПВП и зидовудина возрастает риск гематологической токсичности. Имеются данные об увеличении риска возникновения гемартрозов и гематом у ВИЧ-положительных пациентов с гемофилией, получающих зидовудин и ибупрофен."},{"name":"Регистрационный номер","value":"П N013504/01"},{"name":"Дата государственной регистрации","value":"20.05.2021"},{"name":"Владелец регистрационного удостоверения","value":"Almirall"},{"name":"Изготовитель","value":"Гедеон Рихтер"},{"name":"Фасовщик","value":"Гедеон Рихтер"},{"name":"Страна бренда","value":"Испания"},{"name":"Страна-производитель","value":"Венгрия"},{"name":"Название препарата","value":"Аэртал"},{"name":"Срок годности","value":"36 мес."}]}],"transitionId":"tr_16217587277310879766"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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  • Артнео капс., 35 г, 30 шт., нейтральный, 1 уп.
    –68 %
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    Артнео капс., 35 г, 30 шт., нейтральный, 1 уп.

    Рейтинг товара: 4.8 из 5
    на основе 310 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 1 362 ₽ вместо 1 390
    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  • Артроцин капс., 36 шт., 1 уп.
    –42 %
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    Артроцин капс., 36 шт., 1 уп.

    Рейтинг товара: 4.6 из 5
    на основе 39 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 497 ₽ вместо 507
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  • Лошадиная сила бальзам-гель Релаксирующий, 125 мл, 125 г, 1 шт., ментол, 1 уп.
    –40 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ab7z5ptijdn/toggleWishlist":{"skuId":"101601801911","productId":974572456,"offerId":"3_KI8NomllUEgFM1y5hFXw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQwdCa29nhvYsLEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIqJfb0AMQt+3Bv/oCGJrfoxEg59zBBw==","sign":"8GCCvXoIe+XPvY5EAiQuqJYzKNX/l8UCUf+2aZBFcd0="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ab7z5ptijdn/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Лошадиная сила бальзам-гель Релаксирующий, 125 мл, 125 г, 1 шт., ментол, 1 уп.

    Рейтинг товара: 4.8 из 5
    на основе 267 оценок
    Цена 470 ₽ вместо 780
    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  • Муравьивит Суставоспас крем-бальзам для тела туба, 44 мл
    –53 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-hsfcspsbbl/toggleWishlist":{"skuId":"942020356","productId":1778175363,"offerId":"zaSz8ctMI1xU3u0oNpTLfw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQwdCa29nhvYsLEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYIg5vzzwYQhK6YwQMYiJvZByDn3MEH","sign":"S8/nQwleh2wSswZUbkPCyEPbtM17tVEVW1yNLkOBZ68="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-hsfcspsbbl/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Муравьивит Суставоспас крем-бальзам для тела туба, 44 мл

    Рейтинг товара: 4.2 из 5
    на основе 6 оценок
    Цена 235 ₽ вместо 499
    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  • МСМ таб., 60 шт.
    –2 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-p5cxoylkfpa/toggleWishlist":{"skuId":"460996021","productId":1778174952,"offerId":"gtitt2quIp7EdpKQvfzGOg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQwdCa29nhvYsLEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYI6JfzzwYQtfvo2wEY1buhBiDn3MEH","sign":"crTtc7x1+mFeZ36qYAdkAH0ssyhPvaAUoegmOLd5ucM="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-p5cxoylkfpa/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    МСМ таб., 60 шт.

    Рейтинг товара: 5 из 5
    на основе 3 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 671 ₽ вместо 685
    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таб., 60 шт.","label":"ulwdl4w53km","count":0,"features":[],"imageMeta":{"namespace":"mpic","groupId":4493501,"key":"img_id885150311492146062.png"}},"quantity":{"step":1,"minimum":1,"maximum":999},"cpaUrl":"/safeclick/data=TxNGOK9vJEN7oLFLeCTKEkrTZoQadGRtjQLqzTxCAYEl31AulbEt2kortXjyKfbNlOHXuzHA2qYTX4CI06xS9iWpu6KHXI6gbTAmtpmWMnkH_Cl5cJEzXJjXSfJ7Fjm_-9orCVf-JdyERCtsBsVBDfltAJtuG7YS-TvbIyQFM4m1dCtgPsTabz2jQJZbFCJX1pqV5vD42gksfisIVv3UNeRtcqpO8Km4A4QfNe4CWb9tDXaoeWqn2Sxw1MkwsVW00QxqKjAkmXiiuv83DMYMUzFxkhmy6uJCy7nEyVHJOXOFF2k-bxZYZgWe_Md88HAujlAedN0B9x33Bcn8gbQSvh3qOW296QUGE9h2b4e2Abn_sOpFXI2xlYX5EhufouVGIiOOUiWTw1RoMYRZHSTTQDkVA5Aqe7ZnNlXzFznptKE1o4jnB4oLTMKSExNqZn04LR43EeBVZRY5KGTJu5Rqr-IwQ9qmdLZE98wiyNyruvwx4-nGNRdM-t8L2GOajgv3WPXAAfycELRAdsFj6r3xkdlbFcGMsEFe1F6D1g6LsbJ0w0_8b5o2YTchjJSoiuuccCwdxGI6DS3utrXtf7N6xgFVu2ID6tU0wUxJ0PH3rWHSE1c3qiq5X6To4pYVA3TemdKlBVFr1PfhxtkLrLdQGDMLpp3UYW4C01RD1Pc5g2upyGrQkhv8S31EgMU9UvPqDJ6OuZqMGdTsyNok1aGPEC5PFJHTbzT_ZeZVzv8XhlEl95PGRB389noX8C2QdXY1XUpgn0SPT6jLHQbui2QE2P7H5wtEkU88e7D5n6E7RtqilVbJJNRsll6jZh-jCwkmEWBrglJqoF1v4uvUlMgBgYYZVIWasru30Rx5naF3suuJNh3ljAFhu95EYQmTSpfAgAEk6U3QfOU5Df1NegbCO08IIgKO0TeqeosdCqj_z6qkxjYmiFuV5Yl3DD_Td0i5FpNDnsROw45yfkDBNMtYAkxVR7kU--s8k0Snd5bY3wJtEfudm3WjxOq4202-T26CuGwLudevSYP1oibmzBcQLdLmpTunXgVeRsVvfgrGhlOhz81TqtBhtlAemSFuig0j32XfElUluyWVBBDKjrPpIrUBgtUHQjCVWz_aJBZvAh_yKYMckb4DyYNOIIqOifafVx_1tqb3Dsykb8XtOrEndChhomiQkW_tIC8ircWjmlQEufkbNn3tTvRU84lvjhUTzQdbmMHgoT9RbZaBJjQQbsZzdkkraAZOmJkS-1xGKM6seyvWuePvJ28DJHgMxc6QxqUdRm_d-qbZLfD0GEakqHdQcWYnb8p4RrcMNKHICB7FY-mQlWC8VCJU6rn6YJDAc_gNRHRyjwoY4JzcZPRtWJ0qIS9dTPt73QVRoZbwbodEB6jwsnOaI9sM2TgtimGNPiPpSuD0RI0a4pOqhzPqLnrGvBjx5AfXPih91V_BsaDJoP7_s-CkuoO_wHyFVAUc4MvJU7dbw13EuYiChE81oUvKsNDvgfLRkxgezdxtU3D1aR7GiKwZkktHrcNvyMorZOFiAPhilb391JZF5KYgVIiSKCIlQ-qAPiSwt_McMAW0iRCmq8dLmEvJ4lgurnmgOeS6XyDmEX2gzgOEjlcUn_7U3JqNevIxOEcxuu2hEQMqjR1ZO4_OCr-tyUV8v3hAbEEDc2y0DfYt5GJ1o1s86KQjtuowsGhySrxBjS6RWukrRAOaXkPKYpuUsy4OzOGAuCMMlVe_KmNO_MePGodd-NfcwiKlCQiehurLUtrvB2jHqnOp8PoTNr6JGoiuN-V9DETnnzBGaoXvYPEe9wU86POKsqxVrxDgQk-GFtfILErqZEh_OMGKRRmwg3kNCS_9d-h73KpyqgAF258Xy7ye_1Lui3mMIK_JuNXo1m2BXbPJHuTOAwYNwri7bOtmNKFfAXoLzedWmaLMcayvtWdc1mgLSOWtJBzNr2OTAU19ASX_1OZZMZNor0jAdSdaNbcVXxIqgBMUh3brYU1_L5TrdMThSN9VqQ0OCqLp82aRLaukJDM6jKyJXhkJdK08W2EDDlhw5wilSP6dtE_8h5Kypg3EtMUvNd1XmjI9lFRaUHi7hpb8xhysx9NW6uqrEM0e74N86vsZAYC3Ia9iEUfiJopiqOOJGyMiN8YQG3ao-O7EAQFDIIWYT66JUDar_ZX3Q4oKB1J9n-yHPkBRE3PAZOLWnw0gtTqaLyMsHuTn8mRn8xU2VJdGxOKNdsTvJjkZd0-lvT6pUsjDdiA-n48MoiN1h02yYlqWxi8vu0AwZfHVSl_Lk8klsQmSkPZHTrPOGvG0v7i7omNHRaf0JXZjgVgbWGvGzwCcRcYJS3BnqfU6Eq8PwHMBadvA97eMC1d0RrW8Kc3nNpjP4iYjGxn1R1lGgTBpQB6B8xreo6-ZcMr_Vlcuj1kGQlVxZSwmoZ90ItH91k81fPQd67usoU9ndhQrM_O-BK9kK39xkiTJf_GdSXTAdzxlEf-CgGaDY4lYu1YpAFRpALpejCDDKRZSOFRDO6VwxzzqKuDbaG6_lDRL55_JHcWHhT8BhBGpy7Pg4HBnu0slN5BdYOQTxepz7uJfouJBC3oW_XhyPw5GV9BlUC0yf5Ii9wd5EevV1vvH_izCmKbmKy_7IvxRHgSQfykpOEvT36sfxCYLrOO1-CsjkWME9uYXcwlyVR1BbBI1bh7l57DNFjbuAqcJQfTjyNs9ZlqTw3XcFDh3EHslUMaJDX0Oznd1bqPpszPMSm8jvpQglNvbKLQQNINkG3zP3cHkaaZZx2_kdzSGpExLR3jpy-faFVxb18EaKY7RWPL_tTrQ1ioHG49kTeepCJIyGudBJGfxim8LXdoXJvJkgXKNeoVFUKVI11CKg0pqdC9Sg_35Y9KLsjBlIWXtWOmHXI2QFwR2lhcQ-lhyLKlvVvQGUbvdI6gR0a7F3A_X6bm_TM0xYzEGFVl9KPEnR6uyjbb11zvQVlHs1mp5nsNHdTT1TlamO9RA62ekNGf2zg8OhDFodKuabbC0G42aG8kqJSpUHx8-UbGpU3lOdDkWH9X_WUGW9O5RU2emiWw8wTLLvj0BEqxAOzdKPEfafhMukQLc6Nxid8OQB-gEc3UEl0i7ZvgAdlGzHZT5Z4gGP5CMwTCGcMuvJRyzq7DyB0cYLtbp8fsEKEuAa_6u5T-ch_UfEyF4sDuvS7zMVly9t_R41xyJ2mpXqArT5rFaSNCFyRkV8jjWc7XT_F6kauwb0D_5OIJ8189GDp6iMYHo7OMvBX7rOfmypEAN41wxP-hDk2aBI15gT09xJcKWKsgzvqMMCLC3-j-Bd3oUYI-tsVpILhowLl_KIunAlwnqs3z18lpQ6f4tM5Z9GZeTlfaRUMQJqstZh5ffTs03Tc1uVluz9_vtJgheiMrhY3Opg4_bOGPyBDImb19qM4fBiRmgEJF4RuP6ZwW1nM23zC2nzE2sHNXztSN2oDmsZB7ftx-sDwBx3yNSz2gvMe48SdiAv3lU1ZJUPhZ1BpBvGj7MY3E4hRUZWHRo2MA,/b64e=1/sign=5a2887cff5d5819eedc97a6b14a8019a/keyno=MARKET_1/*","showUid":"17186734734805616009306006","cartLink":"/my/cart","showNotificationWhenDeleteItem":true,"isLavka":false,"isError":false,"isEats":false,"isCR":false,"isM2bEdoOnlyEnable":false,"isEatsMarketIntegration":true,"isCartButtonNext":false,"isUpsalePopupCRExp":false,"baobabClientDataAdditionToCart":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQwdCa29nhvYsLEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYI6JfzzwYQtfvo2wEY1buhBiDn3MEH","sign":"crTtc7x1+mFeZ36qYAdkAH0ssyhPvaAUoegmOLd5ucM="},"target":"cart_addition"},"baobabClientDataDeletionFromCart":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQwdCa29nhvYsLEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYI6JfzzwYQtfvo2wEY1buhBiDn3MEH","sign":"crTtc7x1+mFeZ36qYAdkAH0ssyhPvaAUoegmOLd5ucM="},"target":"cart_deletion"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-p5cxoylkfpa/addToCartButton":{"name":"@light/AddToCartButtonSnippet"}}}
  • Глюкозамин-хондроитиновый комплекс капс., 90 шт.
    –1 %
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    Глюкозамин-хондроитиновый комплекс капс., 90 шт.

    Рейтинг товара: 4.8 из 5
    на основе 113 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 389 ₽ вместо 393
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  • Ревмафлекс капс., 60 шт., нейтральный, 1 уп.
    –1 %
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    Ревмафлекс капс., 60 шт., нейтральный, 1 уп.

    Рейтинг товара: 4.5 из 5
    на основе 14 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 948 ₽ вместо 958
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  • Картилокс пор., 45 г, 30 шт., апельсин, 1 уп.
    –1 %
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    Картилокс пор., 45 г, 30 шт., апельсин, 1 уп.

    Рейтинг товара: 4.6 из 5
    на основе 39 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 2 359 ₽ вместо 2 383
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  • Хонда капс., 30 шт., 1 уп.
    –1 %
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    Хонда капс., 30 шт., 1 уп.

    Рейтинг товара: 4.8 из 5
    на основе 9 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 407 ₽ вместо 411
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  • Артра МСМ таб. п/о плён., 101.4 г, 60 шт., 1 уп.
    –1 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-mvaw6y1x0xj/toggleWishlist":{"skuId":"101849512749","productId":1776499600,"offerId":"1evDhzN1VHp7b2xJeNi0aw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQwdCa29nhvYsLEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIkPeMzwYQrfbQtfsCGNnxzwYg59zBBw==","sign":"8/CB9jNPFXsroSDk/FTG2r+2BUDdeomTb637p/42Ot4="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-mvaw6y1x0xj/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Артра МСМ таб. п/о плён., 101.4 г, 60 шт., 1 уп.

    Рейтинг товара: 4.8 из 5
    на основе 1121 оценка
    С картой  Пэй
    Цена с картой Яндекс Пэй 2 752 ₽ вместо 2 780
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  • Хондрамин таб., 10 мг, 40 шт., 1 уп.
    –1 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-yt24nic8gfd/toggleWishlist":{"skuId":"667636001","productId":1778175175,"offerId":"Aw3Y_K2bmwaSlALqQvoEaQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQwdCa29nhvYsLEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYIx5nzzwYQoaKtvgIY1qjZByDn3MEH","sign":"7FR84rYWglXSxlJa8bEQitOgnrlugMZI2I8e1kOfd6M="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-yt24nic8gfd/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Хондрамин таб., 10 мг, 40 шт., 1 уп.

    Рейтинг товара: 4.7 из 5
    на основе 30 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 563 ₽ вместо 569
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Инструкция

Показания к применению

Купирование воспаления и болевого синдрома при:
— люмбаго;
— зубной боли;
— плечелопаточном периартрите;
— ревматическом поражении мягких тканей.
Симптоматическое лечение:
— ревматоидного артрита;
— остеоартроза;
— анкилозирующего спондилита.

Противопоказания

Эрозивно-язвенные поражения ЖКТ в фазе обострения;
— желудочно-кишечное кровотечение или подозрение на него;
— указания в анамнезе на бронхоспазм, крапивницу, ринит после приема ацетилсалициловой кислоты или других НПВС (полный или неполный синдром непереносимости ацетилсалициловой кислоты - риносинусит, крапивница, полипы слизистой оболочки носа, бронхиальная астма);
— период после проведения аортокоронарного шунтирования;
— выраженная печеночная недостаточность или активное заболевание печени;
— нарушения кроветворения и коагуляции;
— выраженная почечная недостаточность, прогрессирующие заболевания почек;
— подтвержденная гиперкалиемия;
— беременность;
— период лактации (грудное вскармливание);
— детский и подростковый возраст до 18 лет;
— повышенная чувствительность к компонентам препарата.

Способ применения и дозы

Внутрь. Таблетки следует проглатывать целиком, запивая достаточным количеством воды. Обычно взрослым назначают по 1 таблетке 100 мг 2 раза в день (одна таблетка утром и одна - вечером).
Полная инструкция
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Аэртал таб. п/о плен.
Аэртал таб. п/о плен., 100 мг, 20 шт.
4.5
(10)
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2 вопроса
Инструкция

532 ₽

Скидка: 21%
–21 %
Вместо:674 ₽
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4.5
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У продавца:10 оценок·0 отзывов
У всех продавцов:143 оценки·48 отзывов
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    Мильгамма р-р для в/м введ., 5 шт.

    Цена 611 ₽ вместо 709
  • Мильгамма композитум таб. п/о, 100 мг+100 мг, 30 шт.
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    Мильгамма композитум таб. п/о, 100 мг+100 мг, 30 шт.

    Цена 717 ₽ вместо 868
  • Глюкозамин-хондроитиновый комплекс капс., 90 шт.
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    Глюкозамин-хондроитиновый комплекс капс., 90 шт.

    Цена 389 ₽ вместо 393
  • Ревмафлекс капс., 60 шт., нейтральный, 1 уп.
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    Ревмафлекс капс., 60 шт., нейтральный, 1 уп.

    Цена 948 ₽ вместо 958
  • Картилокс пор., 45 г, 30 шт., апельсин, 1 уп.
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    Картилокс пор., 45 г, 30 шт., апельсин, 1 уп.

    Цена 2 359 ₽ вместо 2 383
  • Хонда капс., 30 шт., 1 уп.
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    Хонда капс., 30 шт., 1 уп.

    Цена 407 ₽ вместо 411
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    Реклама
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  • Артнео капс., 35 г, 30 шт., нейтральный, 1 уп.
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    Артнео капс., 35 г, 30 шт., нейтральный, 1 уп.

    Цена 1 362 ₽ вместо 4 225
  • Тербинафин крем, 1%, 15 г, 1 шт.
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    Тербинафин крем, 1%, 15 г, 1 шт.

    Цена 79 ₽ вместо 80
  • Артроцин капс., 36 шт., 1 уп.
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    Артроцин капс., 36 шт., 1 уп.

    Цена 497 ₽ вместо 853
  • МСМ таб., 60 шт.
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    МСМ таб., 60 шт.

    Цена 668 ₽ вместо 675
  • Дипроспан сусп. д/ин., 2мг+5мг/мл, 1 мл, 1 шт.
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    Дипроспан сусп. д/ин., 2мг+5мг/мл, 1 мл, 1 шт.

    Цена 796 ₽
  • Эвалар Чай Эвалар БИО при повышенном содержании мочевой кислоты, 20 фильтр-пакетов
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    Эвалар Чай Эвалар БИО при повышенном содержании мочевой кислоты, 20 фильтр-пакетов

    Цена 194 ₽ вместо 224
  • БиоГая Пробиотик капли детск. фл., 5 мл, 1 уп.
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    БиоГая Пробиотик капли детск. фл., 5 мл, 1 уп.

    Цена 1 752 ₽ вместо 3 500
  • Лимфомиозот капли д/вн. приема, 30 мл
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    Лимфомиозот капли д/вн. приема, 30 мл

    Цена 910 ₽ вместо 1 081
  • Артра МСМ таб. п/о плён., 101.4 г, 60 шт., 1 уп.
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    Артра МСМ таб. п/о плён., 101.4 г, 60 шт., 1 уп.

    Цена 2 752 ₽ вместо 2 780
  • ЛимфоТранзит концентрат напитка фл., 100 мл
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    ЛимфоТранзит концентрат напитка фл., 100 мл

    Цена 361 ₽ вместо 365
  • Хондрамин таб., 10 мг, 40 шт., 1 уп.
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    Хондрамин таб., 10 мг, 40 шт., 1 уп.

    Цена 563 ₽ вместо 569
  • Коллаген для суставов капс., 120 шт.
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    Коллаген для суставов капс., 120 шт.

    Цена 811 ₽ вместо 992
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    Реклама
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  • Муравьивит Суставоспас крем-бальзам для тела туба, 44 мл
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    Муравьивит Суставоспас крем-бальзам для тела туба, 44 мл

    Цена 235 ₽ вместо 499
  • Лошадиная сила бальзам-гель Релаксирующий, 125 мл, 125 г, 1 шт., ментол, 1 уп.
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    Лошадиная сила бальзам-гель Релаксирующий, 125 мл, 125 г, 1 шт., ментол, 1 уп.

    Цена 470 ₽ вместо 780
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