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Описание

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Аквадетрим таб. раств., 2000 ME, 60 шт.

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5.0

(6)

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Коротко о товаре

Артикул Маркета

4343815758

Дозировка

2000 ME

Количество штук в упаковке

60 шт.

Тип препарата

лекарственный препарат

Действующее вещество

Колекальциферол

Инструкция

Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.

Есть противопоказания, посоветуйтесь с врачом

Где купить

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Цена с картой Яндекс Пэй:637 ₽/уп

Скидка вам: 13%

ВАМ–13 %

Вместо: 643 ₽/уп~~729~~ ₽/уп

Завтра, курьер Маркета • 99 ₽

1 уп = 60 шт

Яндекс

Рейтинг 4.9 из 5

17Котзывов

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действием солнечных лучей. По сравнению с витамином D2 характеризуется на 25 % более высокой активностью.\u003Cbr\u003EВитамин D связывается со специфическим рецептором витамина D (VDR), который регулирует экспрессию многих генов, включая гены ионного канала TRPV6 (обеспечивает абсорбцию кальция в кишечнике), CALB1 (кальбиндин; обеспечивает транспорт кальция в кровеносное русло), BGLAP (остеокальцин; обеспечивает минерализацию костной ткани и гомеостаз кальция), SPP1 (остеопонтин; регулирует миграцию остеокластов), REN (ренин; обеспечивает регуляцию артериального давления, являясь ключевым элементом ренин-ангиотензин-альдостероновой системы регуляции), IGFBP (связывающий белок инсулинподобного фактора роста; усиливает действие инсулинподобного фактора роста), FGF23 и FGFR23 (фактор роста фибробластов 23; регулируют уровни кальция, фосфат-аниона, процессы клеточного деления фибробластов), TGFB1 (трансформирующий фактор роста бета-1; регулирует процессы клеточного деления и дифференцировки остеоцитов, хондроцитов, фибробластов и кератиноцитов), LRP2 (ЛПНП-рецептор-связанный белок 2; является посредником эндоцитоза липопротеинов низкой плотности), INSR (рецептор инсулина; обеспечивает эффекты инсулина на любые типы клеток).\u003Cbr\u003EВитамин D3 является активным антирахитическим фактором.\u003Cbr\u003EСамой важной функцией витамина D3 является регулирование метаболизма кальция и фосфатов, что способствует правильной минерализации и росту скелета.\u003Cbr\u003EКолекальциферол играет существенную роль в абсорбции кальция и фосфатов в кишечнике, в транспорте минеральных солей и в процессе кальцификации костей, регулирует также выведение кальция и фосфатов почками.\u003Cbr\u003EКонцентрация ионов кальция в крови обуславливает поддержание тонуса мышц скелетной мускулатуры, функцию миокарда, способствует проведению нервного возбуждения, регулирует процесс свертывания крови.\u003Cbr\u003EНедостаток витамина D в пище, нарушение его всасывания, дефицит кальция, а также недостаточное пребывание на солнце в период быстрого роста ребенка приводит к рахиту, у взрослых − к остеомаляции, у беременных могут возникнуть симптомы тетании, нарушение процессов обызвествления костей новорожденных.\u003Cbr\u003EПовышенная потребность в витамине D возникает у женщин в период менопаузы, поскольку у них часто развивается остеопороз в связи с гормональными нарушениями.\u003Cbr\u003EВитамин D обладает рядом т. н. внескелетных эффектов.\u003Cbr\u003EВитамин D участвует в функционировании иммунной системы путем модуляции уровней цитокинов и регулирует деление лимфоцитов Т-хелперов и дифференцировку В-лимфоцитов.\u003Cbr\u003EВ ряде исследований отмечено снижение заболеваемости инфекциями дыхательных путей на фоне приема витамина D.\u003Cbr\u003EПоказано, что витамин D является важным звеном гомеостаза иммунной системы: предотвращает аутоиммунные заболевания (сахарный диабет 1 типа, рассеянный склероз, ревматоидный артрит, воспалительные болезни кишечника и др.).\u003Cbr\u003EВитамин D обладает антипролиферативным и продифференцирующим эффектами, которые обуславливают онкопротективное действие витамина D. Отмечено, что частота некоторых опухолей (рак молочной железы, рак толстого кишечника) повышается на фоне низкого уровня витамина D в крови.\u003Cbr\u003EВитамин D участвует в регуляции углеводного и жирового метаболизма путем влияния на синтез IRS1 (субстрат рецептора инсулина 1; участвует во внутриклеточных путях проведения сигнала рецептора инсулина), IGF (инсулинподобный фактор роста; регулирует баланс жировой и мышечной ткани), PPAR-δ (активированный рецептор пролифераторов пероксисом, тип δ; способствует переработке избыточного холестерина).\u003Cbr\u003EПо данным эпидемиологических исследований дефицит витамина D ассоциирован с риском метаболических нарушений (метаболический синдром и сахарный диабет 2 типа).\u003Cbr\u003EРецепторы и метаболизирующие ферменты витамина D экспрессируются в артериальных сосудах, сердце и практически всех клетках и тканях, имеющих отношение к патогенезу сердечно-сосудистых заболеваний. На животных моделях показаны антиатеросклеро-тическое действие, супрессия ренина и предупреждение повреждения миокарда под действием витамина D. Низкие уровни витамина D у человека связаны с неблагоприятными факторами риска сердечно-сосудистой патологии, такими как сахарный диабет, дислипидемия, артериальная гипертензия, и ассоциированы с риском сердечно-сосудистых катастроф, в т.ч. инсультов.\u003Cbr\u003EВ исследованиях на экспериментальных моделях болезни Альцгеймера показано, что витамин D3 снижал накопление амилоида в мозге и улучшал когнитивную функцию.\u003Cbr\u003EВ неитервенционных исследованиях у человека показано, что частота развития деменции и болезни Альцгеймера увеличивается на фоне низкого уровня витамина D и низкого диетарного потребления витамина D. Отмечалось ухудшение когнитивной функции и заболеваемости болезнью Альцгеймера при низких уровнях витамина D."},{"description":"","filters":[{"id":50921473,"name":"Состав"}],"isMainProperty":false,"name":"Состав","value":"1 таблетка содержит: действующее вещество: витамин D3 100 SD/S Ph сухой – 10 мг / 20 мг (соответствует 1000 МЕ / 2000 МЕ колекальциферола) [действующее вещество: колекальциферол (витамин D3 кристаллический); вспомогательные вещества: крахмал модифицированный, сахароза, натрия аскорбат кристаллический, триглицериды со средней длиной цепи, кремния диоксид, d,l-альфа-токоферол]; вспомогательные вещества: маннитол, натрия бензоат."},{"description":"","filters":[{"id":50921347,"name":"Взаимодействие"}],"isMainProperty":false,"name":"Взаимодействие","value":"Противоэпилептические средства, рифампицин, колестирамин снижают реабсорбцию витамина D3.\u003Cbr\u003EПрименение одновременно с тиазидными диуретиками повышает риск проявления гиперкальциемии.\u003Cbr\u003EСопутствующая терапия сердечными гликозидами (наперстянкой) может увеличивать их токсический потенциал вследствие гиперкальциемии. У таких пациентов необходимо контролировать показатели ЭКГ и уровня кальция в плазме крови и моче, корректировать дозы сердечных гликозидов. А также, необходимо контролировать уровни дигоксина и дигитоксина в плазме крови при наличии показаний.\u003Cbr\u003EСопутствующая терапия глюкокортикостероидами может снижать эффективность витамина D3.\nПри одновременном применении с сердечными гликозидами возможно усиление токсического действия сердечных гликозидов (повышается риск развития нарушений ритма сердца).\n\nПри одновременном применении с тиазидными диуретиками повышается риск развития гиперкальциемии."},{"description":"","filters":[{"id":50921465,"name":"Показания к применению"}],"isMainProperty":false,"name":"Показания к применению","value":"Профилактика и лечение дефицита витамина D.\u003Cbr\u003EПрофилактика и лечение рахита.\u003Cbr\u003EПри комплексном лечении остеопороза, в том числе постменопаузального."},{"description":"","filters":[{"id":50925451,"name":"Противопоказания"}],"isMainProperty":false,"name":"Противопоказания","value":"Повышенная чувствительность к компонентам препарата. Гипервитаминоз D, повышенная концентрация кальция в крови (гиперкальциемия), повышенное выделение кальция с мочой (гиперкальциурия), мочекаменная болезнь (образование кальциевых оксалатных камней), саркоидоз, острые и хронические заболевания печени и почек, почечная недостаточность, активная форма туберкулеза легких, псевдогипопаратиреоз, дефицит сахаразы / изомальтазы, непереносимость фруктозы, глюкозо-галактозная мальабсорбция."},{"description":"","filters":[{"id":50921469,"name":"Способ применения и дозы"}],"isMainProperty":false,"name":"Способ применения и дозы","value":"Внутрь.\u003Cbr\u003EТаблетку растворить в воде комнатной температуры (количество воды не менее 15 мл – 1 столовая ложка).\u003Cbr\u003EРастворение таблетки занимает некоторое время (около 1-2 минут).\u003Cbr\u003EИндивидуальный, в зависимости от показаний, применяемой лекарственной формы и возраста пациента."},{"description":"","filters":[{"id":50921474,"name":"Применение при беременности"}],"isMainProperty":false,"name":"Применение при беременности","value":"В период беременности не следует применять витамин D3 в высоких дозах из-за возможности проявления тератогенного действия в случае передозировки. В период беременности следует избегать превышения рекомендованных доз витамина D3, так как возможно развитие гиперкальциемии, которая может привести к задержке умственного и физического развития плода.\u003Cbr\u003EС осторожностью следует назначать витамин D3 у женщин, кормящих ребенка грудью – препарат, принимаемый в высоких дозах матерью, может вызвать симптомы передозировки у ребенка."},{"description":"","filters":[{"id":50921464,"name":"Побочные действия"}],"isMainProperty":false,"name":"Побочные действия","value":"Повышенная чувствительность к компонентам препарата, гипервитаминоз D (симптомы гипервитаминоза: потеря аппетита, тошнота, рвота; головные, мышечные и суставные боли; запоры; сухость в полости рта; полиурия; слабость; нарушение психики, в том числе депрессия; потеря массы тела; нарушение сна; повышение температуры; в моче появляется белок, лейкоциты, гиалиновые цилиндры; повышение уровня кальция в крови и его выделение с мочой; возможен кальциноз почек, кровеносных сосудов, легких).\u003Cbr\u003EПри появлении признаков гипервитаминоза D необходимо отменить препарат, ограничить поступление кальция, назначить витамины А, С и В."},{"description":"","filters":[{"id":50921468,"name":"Передозировка"}],"isMainProperty":false,"name":"Передозировка","value":"Симптомы передозировки: снижение аппетита, тошнота, рвота, запоры, беспокойство, жажда, полиурия, диарея, кишечная колика. Частыми симптомами являются головная боль, мышечные и суставные боли, нарушения психики, в том числе депрессия, ступор, атаксия и прогрессирующая потеря массы тела. Развивается нарушение функции почек с альбуминурией, эритроцитурией и полиурией, повышенной потерей калия, гипостенурией, никтурией и повышением артериального давления.\u003Cbr\u003EВ тяжелых случаях может возникнуть помутнение роговицы, реже отек сосочка зрительного нерва, воспаление радужной оболочки вплоть до развития катаракты.\u003Cbr\u003EМогут образоваться камни в почках, происходит процесс кальцификации мягких тканей, в том числе кровеносных сосудов, сердца, легких и кожи.\u003Cbr\u003EРедко развивается холестатическая желтуха.\u003Cbr\u003EЛечение\u003Cbr\u003EПрервать применение препарата. Обратиться к врачу. Принимать большое количество жидкости. При необходимости может потребоваться госпитализация."},{"description":"","filters":[{"id":50921467,"name":"Условия хранения"}],"isMainProperty":false,"name":"Условия хранения","value":"При температуре не выше 25 °С в оригинальной упаковке (контурная ячейковая упаковка в пачке).\u003Cbr\u003EХранить в недоступном для детей месте."},{"description":"","filters":[{"id":50921466,"name":"Особые указания"}],"isMainProperty":false,"name":"Особые указания","value":"С осторожностью\u003Cbr\u003ECостояние иммобилизации, атеросклероз, в период беременности и грудного вскармливания.\u003Cbr\u003EУ пациентов, принимающих тиазидные диуретики, а также, у пациентов с сердечно-сосудистыми заболеваниями, принимающих сердечные гликозиды.\u003Cbr\u003EУ грудных детей при предрасположенности к раннему зарастанию родничков (когда от рождения установлены малые размеры переднего темечка).\u003Cbr\u003EИзбегать передозировки.\u003Cbr\u003EИндивидуальное обеспечение определенной потребности должно учитывать все возможные источники этого витамина.\u003Cbr\u003EСлишком высокие дозы витамина D3, применяемые продолжительно или ударные дозы, могут быть причиной хронического гипервитаминоза D3.\u003Cbr\u003EОпределение суточной потребности ребенка в витамине D и способа его применения должны устанавливаться врачом индивидуально и каждый раз подвергаться коррекции во время периодических обследований, особенно в первые месяцы жизни.\u003Cbr\u003EПри достижении адекватного уровня концентрации витамина D в крови (\u003E 30 нг/мл 25(ОН)D) у взрослых возможно продолжение поддерживающей терапии препаратом Аквадетрим в дозе 1500-2000 МЕ (1½-2 таблетки 1000 МЕ или 1 таблетка 2000 МЕ) в сутки.\u003Cbr\u003EПри отсутствии воды таблетку можно растворить во рту.\u003Cbr\u003EНе применять одновременно с витамином D3 высоких доз кальция.\u003Cbr\u003EВо время лечения необходим периодический контроль концентрации фосфатов в крови и моче.\u003Cbr\u003EПри длительном приеме колекальциферола необходимо регулярно определять уровень кальция в сыворотке крови и моче, а также оценивать функцию почек путем измерения сывороточного уровня креатинина. При необходимости, следует корректировать дозу колекальциферола в зависимости от уровня кальция в сыворотке крови.\u003Cbr\u003EИз-за содержания сахарозы данный препарат не должен назначаться пациентам с редкими наследственными нарушениями, связанными с непереносимостью фруктозы, синдромом мальабсорбции глюкозы-галактозы или недостаточностью сахаразы-изомальтазы.\u003Cbr\u003EДанный препарат содержит 16,4 мг и 32,8 мг натрия на 1 таблетку растворимую 1000 МЕ и 2000 МЕ соответственно. 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Цена с картой Яндекс Пэй 646 ₽ вместо 660
–1 %
Аквадетрим таб. раств., 500 МЕ, 90 шт.
Рейтинг товара: 4.9 из 5
на основе 17 оценок
С картой  Пэй
Цена с картой Яндекс Пэй 608 ₽ вместо 614
–18 %
Аквадетрим капли д/вн. приема фл.-капельница, 1 шт.
Рейтинг товара: 4.9 из 5
на основе 124 оценки
Цена 222 ₽ вместо 272
Вигантол р-р д/вн. приема масл., 1 шт.
Рейтинг товара: 4.8 из 5
на основе 99 оценок
Цена 184 ₽
Фортедетрим капс., 10000 МЕ, 30 шт.
Рейтинг товара: 4.8 из 5
на основе 77 оценок
Цена 1 589 ₽
–34 %
ПРОМОКОД –15 %
Магне B6 таб. п/о, 100 шт.
Рейтинг товара: 4.9 из 5
на основе 176 оценок
С картой  Пэй
Цена с картой Яндекс Пэй 797 ₽ вместо 805
–1 %
ДэТриФерол капли д/вн. приема фл., 1 шт.
Рейтинг товара: 4.9 из 5
на основе 30 оценок
С картой  Пэй
Цена с картой Яндекс Пэй 256 ₽ вместо 259
–21 %
Фортедетрим капс., 10000 МЕ, 30 шт.
Рейтинг товара: 5 из 5
на основе 30 оценок
Цена 1 563 ₽ вместо 1 979
Сорбифер дурулес таб. п/о, 30 шт.
Рейтинг товара: 4.9 из 5
на основе 97 оценок
Цена 700 ₽
–7 %
Кальцемин адванс таб. п/о, 30 шт.
Рейтинг товара: 5 из 5
на основе 38 оценок
С картой  Пэй
Цена с картой Яндекс Пэй 760 ₽ вместо 768
–11 %
Магнелис B6 таб. п/о, 50 шт.
Рейтинг товара: 5 из 5
на основе 17 оценок
С картой  Пэй
Цена с картой Яндекс Пэй 415 ₽ вместо 419

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Инструкция

Показания к применению

Профилактика и лечение дефицита витамина D.
Профилактика и лечение рахита.
При комплексном лечении остеопороза, в том числе постменопаузального.

Противопоказания

Повышенная чувствительность к компонентам препарата. Гипервитаминоз D, повышенная концентрация кальция в крови (гиперкальциемия), повышенное выделение кальция с мочой (гиперкальциурия), мочекаменная болезнь (образование кальциевых оксалатных камней), саркоидоз, острые и хронические заболевания печени и почек, почечная недостаточность, активная форма туберкулеза легких, псевдогипопаратиреоз, дефицит сахаразы / изомальтазы, непереносимость фруктозы, глюкозо-галактозная мальабсорбция.

Способ применения и дозы

Внутрь.
Таблетку растворить в воде комнатной температуры (количество воды не менее 15 мл – 1 столовая ложка).
Растворение таблетки занимает некоторое время (около 1-2 минут).
Индивидуальный, в зависимости от показаний, применяемой лекарственной формы и возраста пациента.

Полная инструкция

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Аквадетрим таб. раств., 2000 ME, 60 шт.

5.0

(6)

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3 вопроса

Инструкция

Цена с картой Яндекс Пэй:637 ₽/уп

Скидка: 13%

–13 %

Вместо: 643 ₽/уп~~729~~ ₽/уп

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5.0

У этого продавца: 6 оценок

•

0 отзывов

У всех продавцов: 132 оценки

•

52 отзыва

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Рекомендуем

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Фортедетрим капс., 10000 МЕ, 30 шт.

Цена 1 563 ₽ вместо 1 979

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Сорбифер дурулес таб. п/о, 30 шт.

Цена 700 ₽

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Кальцемин адванс таб. п/о, 30 шт.

Цена 760 ₽ вместо 817

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Магнелис B6 таб. п/о, 50 шт.

Цена 415 ₽ вместо 466

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Йодомарин таб., 0.2 мг, 50 шт.

Цена 130 ₽ вместо 152

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Gentle Iron (Iron Bisglycinate) капс., 25 мг, 15 г, 90 шт.

Цена 1 376 ₽ вместо 1 787

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Solgar, Omega-3, EPA & DHA, Triple Strength, 950 mg, омега-3, ЭПК и ДГК, тройной концентрации, 950 мг, 50 капсул

Цена 2 495 ₽ вместо 3 275

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БиоГая Пробиотик капли детск. фл., 5 мл, 1 уп.

Цена 2 025 ₽ вместо 3 500

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Argitos Коллоидное серебро спрей д/мест. прим. фл., 30 мл, 40 г, нейтральный

Цена 365 ₽ вместо 395

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Хило-комод р-р увлажняющий офтальмологический конт., 1 мг/мл, 10 мл, 1 шт.

Цена 742 ₽ вместо 749

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Магний хелат таб., 85 мл, 1.4 г, 60 шт.

Цена 941 ₽ вместо 1 166

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Пастилки California Gold Nutrition Vitamin D3 gummies со вкусом фруктов и ягод, 280 г, 90 шт.

Цена 421 ₽ вместо 425

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ЛимфоТранзит концентрат напитка фл., 100 мл

Цена 332 ₽ вместо 390

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Ревмафлекс капс., 60 шт.

Цена 772 ₽ вместо 950

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Описание

Аквадетрим таб. раств., 2000 ME, 60 шт.

Коротко о товаре

Где купить

Цена с картой Яндекс Пэй:637 ₽/уп

Аквадетрим капли д/вн.приема фл.-капельница, 1 шт.

Аквадетрим, таблетки 2000 МЕ, 30 шт.

Аквадетрим таб. раств., 500 МЕ, 90 шт.

Аквадетрим капли д/вн. приема фл.-капельница, 1 шт.

Вигантол р-р д/вн. приема масл., 1 шт.

Фортедетрим капс., 10000 МЕ, 30 шт.

Магне B6 таб. п/о, 100 шт.

ДэТриФерол капли д/вн. приема фл., 1 шт.

Фортедетрим капс., 10000 МЕ, 30 шт.

Сорбифер дурулес таб. п/о, 30 шт.

Кальцемин адванс таб. п/о, 30 шт.

Магнелис B6 таб. п/о, 50 шт.

Инструкция

Показания к применению

Противопоказания

Способ применения и дозы

Цена с картой Яндекс Пэй:637 ₽/уп

Рекомендуем

Аквадетрим капли д/вн.приема фл.-капельница, 1 шт.

Аквадетрим таб. раств., 500 МЕ, 90 шт.

Аквадетрим капли д/вн. приема фл.-капельница, 1 шт.

Аквадетрим, таблетки 2000 МЕ, 30 шт.

Вигантол р-р д/вн. приема масл., 1 шт.

Фортедетрим капс., 10000 МЕ, 30 шт.

Магне B6 таб. п/о, 100 шт.

ДэТриФерол капли д/вн. приема фл., 1 шт.

Фортедетрим капс., 10000 МЕ, 30 шт.

Сорбифер дурулес таб. п/о, 30 шт.

Кальцемин адванс таб. п/о, 30 шт.

Магнелис B6 таб. п/о, 50 шт.

Йодомарин таб., 0.2 мг, 50 шт.

Gentle Iron (Iron Bisglycinate) капс., 25 мг, 15 г, 90 шт.

Solgar, Omega-3, EPA & DHA, Triple Strength, 950 mg, омега-3, ЭПК и ДГК, тройной концентрации, 950 мг, 50 капсул

БиоГая Пробиотик капли детск. фл., 5 мл, 1 уп.

Argitos Коллоидное серебро спрей д/мест. прим. фл., 30 мл, 40 г, нейтральный

Хило-комод р-р увлажняющий офтальмологический конт., 1 мг/мл, 10 мл, 1 шт.

Магний хелат таб., 85 мл, 1.4 г, 60 шт.

Пастилки California Gold Nutrition Vitamin D3 gummies со вкусом фруктов и ягод, 280 г, 90 шт.

ЛимфоТранзит концентрат напитка фл., 100 мл

Ревмафлекс капс., 60 шт.

Цена с картой Яндекс Пэй:637 ₽/уп

Цена с картой Яндекс Пэй:637 ₽/уп