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Описание

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Аллопуринол таб., 100 мг, 50 шт.

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5.0
(27)
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Дозировка: 100 мг

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Количество штук в упаковке, шт.: 50

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Коротко о товаре

Артикул Маркета
4453166608
Тип препарата
Назначение
Действующее вещество
Возраст
от 3 лет
Инструкция
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Рецидивирующие смешанные оксалатно-кальциевые почечные камни (при наличии урикозурии)."},{"name":"Противопоказания","value":"Гиперчувствительность к аллопуринолу или любому другому компоненту препарата; печеночная недостаточность; тяжелая почечная недостаточность (стадия азотемии); первичный (идиопатический) гемохроматоз; бессимптомная гиперурикемия, острый приступ подагры; непереносимость лактозы, дефицит лактазы, синдром глюкозо- галактозной мальабсорбции; беременность, период грудного вскармливания, детский возраст до 3 лет."},{"name":"Состав","value":"1 таблетка дозировки 100 мг препарата содержит:\u003Cbr /\u003Eактивное вещество: аллопуринол - 100 мг;\u003Cbr /\u003Eвспомогательные вещества: сахароза (сахар-песок рафинированный) - 20 мг, крахмал картофельный - 77,68 мг, магния стеарат (магний стеариновокислый) - 1 мг, желатин пищевой -1,32 мг.\u003Cbr /\u003E1 таблетка дозировки 300 мг препарата содержит:\u003Cbr /\u003Eактивное вещество: аллопуринол - 300 мг;\u003Cbr /\u003Eвспомогательные вещества: лактозы моногидрат (сахар молочный) - 49 мг; целлюлоза микрокристаллическая - 20 мг; карбоксиметилкрахмал натрия (примогель) - 20 мг; желатин пищевой - 5 мг; магния стеарат - 4 мг; кремния диоксид коллоидный (аэросил) - 2 мг."},{"name":"Действующее вещество","value":"Аллопуринол","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["27144131:28708813"]}}},{"name":"Способ применения и дозы","value":"Внутрь. Препарат следует принимать один раз в день после еды, запивая большим количеством воды. Если суточная доза превышает 300 мг или наблюдаются симптомы непереносимости со стороны желудочно-кишечного тракта, то дозу необходимо делить на несколько приемов.\u003Cbr /\u003EДля осуществления начальной терапии следует применять аллопуринол в иных дозировках (100 мг) один раз в день. Если этой дозы недостаточно для того, чтобы должным образом снизить концентрацию мочевой кислоты в сыворотке крови, то суточную дозу препарата можно постепенно увеличивать до достижения желаемого эффекта. Следует проявлять особую осторожность при нарушении функции почек.\u003Cbr /\u003EПри повышении дозы аллопуринола каждые 1-3 недели необходимо определять концентрацию мочевой кислоты в сыворотке крови.\u003Cbr /\u003EРекомендованная доза препарата составляет 300-600 мг в сутки при среднетяжелом течении; 600-900 мг в сутки при тяжелом течении. Максимальная суточная доза - 900 мг. Рекомендованная доза для детей от 3 до 10 лет - по 5-10 мг/кг/сутки.\u003Cbr /\u003EРекомендованная доза для детей от 10 до 15 лет составляет 10-20 мг/кг/сутки. Суточная доза препарата не должна превышать 400 мг.\u003Cbr /\u003EАллопуринол редко применяется для детской терапии. Исключение составляют злокачественные онкологические заболевания (особенно лейкозы) и некоторые ферментативные нарушения (например, синдром Леша-Найхана).\u003Cbr /\u003EПоскольку аллопуринол и его метаболиты выводятся из организма почками, нарушение функции почек может приводить к задержке препарата и его метаболитов в организме с последующим удлинением периода полувыведения этих соединений из плазмы крови.\u003Cbr /\u003EАллопуринол и его производные удаляются из организма при помощи гемодиализа. Если сеансы гемодиализа проводятся 2-3 раза в неделю, то целесообразно определить необходимость перехода на альтернативный режим терапии - прием 300-400 мг аллопуринола сразу после завершения сеанса гемодиализа (между сеансами гемодиализа препарат не принимается).\u003Cbr /\u003EДля коррекции дозы препарата необходимо с оптимальными интервалами оценивать концентрацию солей мочевой кислоты в сыворотке крови, а также концентрацию мочевой кислоты и уратов в моче."},{"name":"Побочные действия","value":"Со стороны сердечно-сосудистой системы: в единичных случаях - артериальная гипертензия, брадикардия.\u003Cbr\u003EСо стороны пищеварительной системы: возможны диспептические явления (в т.ч. тошнота, рвота), диарея, транзиторное повышение активности трансаминаз в сыворотке крови; редко - гепатит; в единичных случаях - стоматит, нарушения функции печени (преходящее повышение активности трансаминаз и ЩФ), стеаторея.\u003Cbr\u003EСо стороны ЦНС и периферической нервной системы: в единичных случаях - слабость, повышенная утомляемость, головная боль, головокружение, атаксия, сонливость, депрессия, кома, парезы, парестезии, судороги, невропатии, нарушения зрения, катаракта, изменения сосочка зрительного нерва, нарушения вкусовых ощущений.\u003Cbr\u003EСо стороны системы кроветворения: в отдельных случаях - тромбоцитопения, агранулоцитоз и апластическая анемия, лейкопения (наиболее вероятны у больных с нарушениями функции почек).\u003Cbr\u003EСо стороны мочевыделительной системы: редко - интерстициальный нефрит; в единичных случаях - отеки, уремия, гематурия.\u003Cbr\u003EСо стороны эндокринной системы: в единичных случаях - бесплодие, импотенция, гинекомастия, сахарный диабет.\u003Cbr\u003EСо стороны обмена веществ: в единичных случаях - гиперлипидемия.\u003Cbr\u003EАллергические реакции: кожная сыпь, гиперемия, зуд; в отдельных случаях - ангиоиммунобластная лимфаденопатия, артралгия, повышение температуры, эозинофилия, лихорадка, синдром Стивенса-Джонсона, синдром Лайелла.\u003Cbr\u003EДерматологические реакции: в единичных случаях - фурункулез, алопеция, обесцвечивание волос."},{"name":"Фармакологическое действие","value":"Аллопуринол является структурным аналогом гипоксантина. Аллопуринол, а также его основной активный метаболит - оксипуринол, ингибируют ксантиноксидазу - фермент, обеспечивающий преобразование гипоксантина в ксантин, и ксантина в мочевую кислоту.\nАллопуринол уменьшает концентрацию мочевой кислоты как в сыворотке крови, так и в моче. Тем самым он предотвращает отложение кристаллов мочевой кислоты в тканях и (или) способствует их растворению. Помимо подавления катаболизма пуринов у некоторых (но не у всех) пациентов с гиперурикемией, большое количество ксантина и гипоксантина становится доступно для повторного образования пуриновых оснований, что приводит к угнетению биосинтеза пуринов de novo по механизму обратной связи, что опосредовано угнетением фермента гипоксантин-гуанин фосфорибозил-трансферазы. Другие метаболиты аллопуринола - аллопуринол-рибозид и оксипуринол-7 рибозид."},{"name":"Фармакологическая группа","value":"противоподагрическое средство - ксантиноксидазы ингибитор."},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 3 лет"},{"name":"Условия хранения","value":"Хранить в защищенном от света месте, при температуре не выше 30 °С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы: тошнота, рвота, диарея, головокружение, олигурия. Большинство симптомов передозировки аллопуринола могут ослабляться за счет повышения его почечной экскреции при обильном потреблении жидкости и соответственном усилении диуреза. Лечение: форсированный диурез; аллопуринол и его метаболиты выводятся при гемодиализе и перитонеальном диализе."},{"name":"Применение при беременности и кормлении грудью","value":"Аллопуринол во время беременности следует принимать только по назначению врача и только при отсутствии терапевтической альтернативы, когда заболевание представляет больший риск для плода и матери, чем аллопуринол. При необходимости применения аллопуринола в период лактации следует решить вопрос о прекращении грудного вскармливания или воздержаться от назначения препарата."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"С осторожностью применять у пациентов, деятельность которых требует высокой концентрации внимания и быстрых психомоторных реакций."},{"name":"Особые указания","value":"С осторожностью:\u003Cbr /\u003EПочечная недостаточность, хроническая сердечная недостаточность, сахарный диабет, артериальная гипертензия, нарушения функции печени, гипотиреоз, пожилой возраст.\u003Cbr /\u003EПациенты, принимающие ингибиторы ангиотензинпревращающего фермента (АПФ) или диуретики.\u003Cbr /\u003EДетский возраст до 15 лет (назначают только во время цитостатической терапии лейкозов и др. злокачественных заболеваний, а также симптоматического лечения ферментных нарушений).\u003Cbr\u003EСиндром лекарственного гиперчувствительности. ССД и ТЭН\u003Cbr /\u003EНа фоне применения аллопуринола поступали сообщения о развитии угрожающих жизни реакций со стороны кожи, такие как синдром Стивенса-Джонсона и токсический эпидермальный некролиз (ССД/ТЭН). Пациентов следует информировать о симптомах этих реакций (прогрессирующая кожная сыпь, часто с пузырьками и поражением слизистых) и тщательно мониторировать их развитие. Наиболее часто ССД/ТЭН развиваются на первых неделях приема препарата. При наличии признаков и симптомов ССД/ТЭН препарат Аллопуринол следует немедленно отменить и более не назначать! Манифестация реакций гиперчувствительности к аллопуринолу может быть самой различной, включая макулопапулезную экзантему, синдром лекарственной гиперчувствительности (DRESS) и ССД/ТЭН. Эти реакции являются клиническим диагнозом и их клинические проявления служат основой для принятия соответствующих решений. Терапию препаратом Аллопуринол следует немедленно прекратить при появлении кожной сыпи или других проявлений реакции гиперчувствительности. Нельзя возобновлять терапию у пациентов с синдромом гиперчувствительности и ССД/ТЭН. Кортикостероиды могут применяться для лечения кожных реакций при гиперчувствительности.\u003Cbr /\u003EХроническое нарушение функции почек\u003Cbr /\u003EПациенты с хроническим нарушением функции почек имеют больший риск развития реакций гиперчувствительности, связанных с аллопуринолом, в том числе и ССД/ТЭН.\u003Cbr /\u003EАллель HLA-B*5801\u003Cbr /\u003EБыло установлено, что присутствие аллеля HLA-B*5801 связано с развитием синдрома гиперчувствительности к аллопуринолу и ССД/ТЭН. Частота присутствия аллеля HLA- В*5801 различна в разных этнических группах и может достигать 20% в популяции китайцев Хань, около 12 % у корейцев и 1-2% у японцев и европейцев. Применение генотипирования для принятия решений о терапии аллопуринолом не исследовалось. Если известно, что пациент является носителем аллеля HLA-B*5801, то аллопуринол следует назначать только, если польза лечения превосходит риск. Следует очень внимательно следить за развитием синдрома гиперчувствительности и ССД/ТЭН. Пациент должен быть проинформирован о необходимости немедленной отмены лечения при первом появлении таких симптомов.\u003Cbr /\u003EНарушение функции печени и почек\u003Cbr /\u003EПри лечении пациентов с нарушенной функцией почек или печени дозу аллопуринола необходимо снизить. У пациентов, получающих лечение по поводу артериальной гипертензии или сердечной недостаточности (например, пациенты, принимающие диуретики или ингибиторы АПФ), может наблюдаться сопутствующее нарушение функции почек, поэтому аллопуринол в этой группе пациентов следует использовать с осторожностью.\u003Cbr /\u003EБессимптомная гиперурикемия сама по себе не является показанием к применению аллопуринола. В таких случаях улучшение состояния пациентов может быть достигнуто благодаря изменениям в диете и потреблению жидкости наряду с устранением основной причины гиперурикемии.\u003Cbr /\u003EОстрый приступ подагры\u003Cbr /\u003EАллопуринол не следует применять до полного купирования острого приступа подагры, поскольку этим можно спровоцировать дополнительное обострение заболевания. Аналогично терапии урикозурическими средствами, начало лечения аллопуринолом может спровоцировать острый приступ подагры. Для того чтобы избежать этого осложнения, рекомендуется проводить профилактическую терапию нестероидными противовоспалительными препаратами или колхицином в течение по меньшей мере одного месяца до назначения аллопуринола. Подробные сведения о рекомендованных дозах, предостережениях и мерах предосторожности можно найти в соответствующей литературе.\u003Cbr /\u003EЕсли острый приступ подагры развивается на фоне терапии аллопуринолом, то прием препарата следует продолжить в той же дозе, а для лечения приступа необходимо назначить подходящее нестероидное противовоспалительное средство.\u003Cbr /\u003EОтложения ксантина\u003Cbr /\u003EВ случаях, когда образование мочевой кислоты значительно усилено (например, злокачественная опухолевая патология и соответствующая противоопухолевая терапия, синдром Леша-Найхана), абсолютная концентрация ксантина в моче в редких случаях может существенно увеличиться, что способствует отложению ксантина в тканях мочевых путей. Вероятность отложения ксантина в тканях можно свести к минимуму благодаря адекватной гидратации, которая обеспечивает оптимальное разведение мочи.\u003Cbr /\u003EВклинение конкрементов из мочевой кислоты\u003Cbr /\u003EАдекватная терапия аллопуринолом может приводить к растворению находящихся в почечных лоханках крупных конкрементов из мочевой кислоты однако, вероятность вклинения этих конкрементов в мочеточники невелика.\u003Cbr /\u003EГемохроматоз\u003Cbr /\u003EОсновной эффект аллопуринола при лечении подагры состоит в подавлении активности фермента ксантиноксидазы. Ксантиноксидаза может участвовать в уменьшении содержания и выведении железа, депонируемого в печени. Исследования, демонстрирующие безопасность терапии аллопуринолом в популяции больных гемохроматозом, отсутствуют. Пациентам с гемохроматозом, а также их кровным родственникам аллопуринол следует назначать с осторожностью.\u003Cbr /\u003EЛактоза\u003Cbr /\u003EКаждая 300 мг таблетка препарата Аллопуринол содержит 49 мг лактозы. Следовательно, этот препарат не должны принимать пациенты с редкой наследственной непереносимостью галактозы, недостаточностью лактазы и синдромом мальабсорбции глюкозы и галактозы."},{"name":"Взаимодействие","value":"При одновременном применении аллопуринол усиливает действие кумариновых антикоагулянтов, аденина арабинозида, а также гипогликемических препаратов (особенно при нарушениях функции почек).\u003Cbr\u003EУрикозурические средства и салицилаты в высоких дозах снижают активность аллопуринола.\u003Cbr\u003EПри одновременном применении аллопуринола и цитостатиков чаще проявляется миелотоксическое действие, чем при раздельном применении.\u003Cbr\u003EПри одновременном применении аллопуринола и азатиоприна или меркаптопурина наблюдается кумуляция последних в организме, т.к. в связи с ингибированием аллопуринолом активности ксантиноксидазы, необходимой для биотрансформации лекарственных средств, замедляется их метаболизм и элиминация."},{"name":"Регистрационный номер","value":"ЛСР-001485/08\nЛП-003429"},{"name":"Дата государственной регистрации","value":"19.03.2018\n26.01.2021"},{"name":"Владелец регистрационного удостоверения","value":"Органика","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["34324371:35649313","7893318:16002709"]}}},{"name":"Изготовитель","value":"Органика"},{"name":"Фасовщик","value":"Органика"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Аллопуринол","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["17796364:18025484"]}}},{"name":"Срок годности","value":"60 мес."}]}},"fullSpecsGrouped":{"13571182203210189380":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"опорно-двигательная система"},{"name":"Назначение","value":"гиперурикемия, мочекаменная болезнь, подагра"},{"name":"Показания к применению","value":"Заболевания, сопровождающиеся гиперурикемией (лечение и профилактика): подагра (первичная и вторичная), мочекаменная болезнь (с образованием уратов).\u003Cbr /\u003EГиперурикемия (первичная и вторичная), возникающая при заболеваниях, сопровождающихся усиленным распадом нуклеопротеидов и повышением содержания мочевой кислоты в крови, в т.ч. при различных гематобластозах (остром лейкозе, хроническом миелолейкозе, лимфосаркоме и др.), при цитостатической и лучевой терапии опухолей (в т.ч. у детей), псориазе, обширных травматических повреждениях, вследствие ферментных нарушений (синдром Леша-Нихена), а также при массивной терапии глюкокортикостероидами, когда вследствие интенсивного распада тканей значительно повышается количество пуринов в крови.\u003Cbr /\u003EМочекислая нефропатия с нарушением функции почек (почечная недостаточность). Рецидивирующие смешанные оксалатно-кальциевые почечные камни (при наличии урикозурии)."},{"name":"Противопоказания","value":"Гиперчувствительность к аллопуринолу или любому другому компоненту препарата; печеночная недостаточность; тяжелая почечная недостаточность (стадия азотемии); первичный (идиопатический) гемохроматоз; бессимптомная гиперурикемия, острый приступ подагры; непереносимость лактозы, дефицит лактазы, синдром глюкозо- галактозной мальабсорбции; беременность, период грудного вскармливания, детский возраст до 3 лет."},{"name":"Состав","value":"1 таблетка дозировки 100 мг препарата содержит:\u003Cbr /\u003Eактивное вещество: аллопуринол - 100 мг;\u003Cbr /\u003Eвспомогательные вещества: сахароза (сахар-песок рафинированный) - 20 мг, крахмал картофельный - 77,68 мг, магния стеарат (магний стеариновокислый) - 1 мг, желатин пищевой -1,32 мг.\u003Cbr /\u003E1 таблетка дозировки 300 мг препарата содержит:\u003Cbr /\u003Eактивное вещество: аллопуринол - 300 мг;\u003Cbr /\u003Eвспомогательные вещества: лактозы моногидрат (сахар молочный) - 49 мг; целлюлоза микрокристаллическая - 20 мг; карбоксиметилкрахмал натрия (примогель) - 20 мг; желатин пищевой - 5 мг; магния стеарат - 4 мг; кремния диоксид коллоидный (аэросил) - 2 мг."},{"name":"Действующее вещество","value":"Аллопуринол"},{"name":"Способ применения и дозы","value":"Внутрь. Препарат следует принимать один раз в день после еды, запивая большим количеством воды. Если суточная доза превышает 300 мг или наблюдаются симптомы непереносимости со стороны желудочно-кишечного тракта, то дозу необходимо делить на несколько приемов.\u003Cbr /\u003EДля осуществления начальной терапии следует применять аллопуринол в иных дозировках (100 мг) один раз в день. Если этой дозы недостаточно для того, чтобы должным образом снизить концентрацию мочевой кислоты в сыворотке крови, то суточную дозу препарата можно постепенно увеличивать до достижения желаемого эффекта. Следует проявлять особую осторожность при нарушении функции почек.\u003Cbr /\u003EПри повышении дозы аллопуринола каждые 1-3 недели необходимо определять концентрацию мочевой кислоты в сыворотке крови.\u003Cbr /\u003EРекомендованная доза препарата составляет 300-600 мг в сутки при среднетяжелом течении; 600-900 мг в сутки при тяжелом течении. Максимальная суточная доза - 900 мг. Рекомендованная доза для детей от 3 до 10 лет - по 5-10 мг/кг/сутки.\u003Cbr /\u003EРекомендованная доза для детей от 10 до 15 лет составляет 10-20 мг/кг/сутки. Суточная доза препарата не должна превышать 400 мг.\u003Cbr /\u003EАллопуринол редко применяется для детской терапии. Исключение составляют злокачественные онкологические заболевания (особенно лейкозы) и некоторые ферментативные нарушения (например, синдром Леша-Найхана).\u003Cbr /\u003EПоскольку аллопуринол и его метаболиты выводятся из организма почками, нарушение функции почек может приводить к задержке препарата и его метаболитов в организме с последующим удлинением периода полувыведения этих соединений из плазмы крови.\u003Cbr /\u003EАллопуринол и его производные удаляются из организма при помощи гемодиализа. Если сеансы гемодиализа проводятся 2-3 раза в неделю, то целесообразно определить необходимость перехода на альтернативный режим терапии - прием 300-400 мг аллопуринола сразу после завершения сеанса гемодиализа (между сеансами гемодиализа препарат не принимается).\u003Cbr /\u003EДля коррекции дозы препарата необходимо с оптимальными интервалами оценивать концентрацию солей мочевой кислоты в сыворотке крови, а также концентрацию мочевой кислоты и уратов в моче."},{"name":"Побочные действия","value":"Со стороны сердечно-сосудистой системы: в единичных случаях - артериальная гипертензия, брадикардия.\u003Cbr\u003EСо стороны пищеварительной системы: возможны диспептические явления (в т.ч. тошнота, рвота), диарея, транзиторное повышение активности трансаминаз в сыворотке крови; редко - гепатит; в единичных случаях - стоматит, нарушения функции печени (преходящее повышение активности трансаминаз и ЩФ), стеаторея.\u003Cbr\u003EСо стороны ЦНС и периферической нервной системы: в единичных случаях - слабость, повышенная утомляемость, головная боль, головокружение, атаксия, сонливость, депрессия, кома, парезы, парестезии, судороги, невропатии, нарушения зрения, катаракта, изменения сосочка зрительного нерва, нарушения вкусовых ощущений.\u003Cbr\u003EСо стороны системы кроветворения: в отдельных случаях - тромбоцитопения, агранулоцитоз и апластическая анемия, лейкопения (наиболее вероятны у больных с нарушениями функции почек).\u003Cbr\u003EСо стороны мочевыделительной системы: редко - интерстициальный нефрит; в единичных случаях - отеки, уремия, гематурия.\u003Cbr\u003EСо стороны эндокринной системы: в единичных случаях - бесплодие, импотенция, гинекомастия, сахарный диабет.\u003Cbr\u003EСо стороны обмена веществ: в единичных случаях - гиперлипидемия.\u003Cbr\u003EАллергические реакции: кожная сыпь, гиперемия, зуд; в отдельных случаях - ангиоиммунобластная лимфаденопатия, артралгия, повышение температуры, эозинофилия, лихорадка, синдром Стивенса-Джонсона, синдром Лайелла.\u003Cbr\u003EДерматологические реакции: в единичных случаях - фурункулез, алопеция, обесцвечивание волос."},{"name":"Фармакологическое действие","value":"Аллопуринол является структурным аналогом гипоксантина. Аллопуринол, а также его основной активный метаболит - оксипуринол, ингибируют ксантиноксидазу - фермент, обеспечивающий преобразование гипоксантина в ксантин, и ксантина в мочевую кислоту.\nАллопуринол уменьшает концентрацию мочевой кислоты как в сыворотке крови, так и в моче. Тем самым он предотвращает отложение кристаллов мочевой кислоты в тканях и (или) способствует их растворению. Помимо подавления катаболизма пуринов у некоторых (но не у всех) пациентов с гиперурикемией, большое количество ксантина и гипоксантина становится доступно для повторного образования пуриновых оснований, что приводит к угнетению биосинтеза пуринов de novo по механизму обратной связи, что опосредовано угнетением фермента гипоксантин-гуанин фосфорибозил-трансферазы. Другие метаболиты аллопуринола - аллопуринол-рибозид и оксипуринол-7 рибозид."},{"name":"Фармакологическая группа","value":"противоподагрическое средство - ксантиноксидазы ингибитор."},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 3 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"Хранить в защищенном от света месте, при температуре не выше 30 °С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы: тошнота, рвота, диарея, головокружение, олигурия. Большинство симптомов передозировки аллопуринола могут ослабляться за счет повышения его почечной экскреции при обильном потреблении жидкости и соответственном усилении диуреза. Лечение: форсированный диурез; аллопуринол и его метаболиты выводятся при гемодиализе и перитонеальном диализе."},{"name":"Применение при беременности и кормлении грудью","value":"Аллопуринол во время беременности следует принимать только по назначению врача и только при отсутствии терапевтической альтернативы, когда заболевание представляет больший риск для плода и матери, чем аллопуринол. При необходимости применения аллопуринола в период лактации следует решить вопрос о прекращении грудного вскармливания или воздержаться от назначения препарата."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"С осторожностью применять у пациентов, деятельность которых требует высокой концентрации внимания и быстрых психомоторных реакций."},{"name":"Особые указания","value":"С осторожностью:\u003Cbr /\u003EПочечная недостаточность, хроническая сердечная недостаточность, сахарный диабет, артериальная гипертензия, нарушения функции печени, гипотиреоз, пожилой возраст.\u003Cbr /\u003EПациенты, принимающие ингибиторы ангиотензинпревращающего фермента (АПФ) или диуретики.\u003Cbr /\u003EДетский возраст до 15 лет (назначают только во время цитостатической терапии лейкозов и др. злокачественных заболеваний, а также симптоматического лечения ферментных нарушений).\u003Cbr\u003EСиндром лекарственного гиперчувствительности. ССД и ТЭН\u003Cbr /\u003EНа фоне применения аллопуринола поступали сообщения о развитии угрожающих жизни реакций со стороны кожи, такие как синдром Стивенса-Джонсона и токсический эпидермальный некролиз (ССД/ТЭН). Пациентов следует информировать о симптомах этих реакций (прогрессирующая кожная сыпь, часто с пузырьками и поражением слизистых) и тщательно мониторировать их развитие. Наиболее часто ССД/ТЭН развиваются на первых неделях приема препарата. При наличии признаков и симптомов ССД/ТЭН препарат Аллопуринол следует немедленно отменить и более не назначать! Манифестация реакций гиперчувствительности к аллопуринолу может быть самой различной, включая макулопапулезную экзантему, синдром лекарственной гиперчувствительности (DRESS) и ССД/ТЭН. Эти реакции являются клиническим диагнозом и их клинические проявления служат основой для принятия соответствующих решений. Терапию препаратом Аллопуринол следует немедленно прекратить при появлении кожной сыпи или других проявлений реакции гиперчувствительности. Нельзя возобновлять терапию у пациентов с синдромом гиперчувствительности и ССД/ТЭН. Кортикостероиды могут применяться для лечения кожных реакций при гиперчувствительности.\u003Cbr /\u003EХроническое нарушение функции почек\u003Cbr /\u003EПациенты с хроническим нарушением функции почек имеют больший риск развития реакций гиперчувствительности, связанных с аллопуринолом, в том числе и ССД/ТЭН.\u003Cbr /\u003EАллель HLA-B*5801\u003Cbr /\u003EБыло установлено, что присутствие аллеля HLA-B*5801 связано с развитием синдрома гиперчувствительности к аллопуринолу и ССД/ТЭН. Частота присутствия аллеля HLA- В*5801 различна в разных этнических группах и может достигать 20% в популяции китайцев Хань, около 12 % у корейцев и 1-2% у японцев и европейцев. Применение генотипирования для принятия решений о терапии аллопуринолом не исследовалось. Если известно, что пациент является носителем аллеля HLA-B*5801, то аллопуринол следует назначать только, если польза лечения превосходит риск. Следует очень внимательно следить за развитием синдрома гиперчувствительности и ССД/ТЭН. Пациент должен быть проинформирован о необходимости немедленной отмены лечения при первом появлении таких симптомов.\u003Cbr /\u003EНарушение функции печени и почек\u003Cbr /\u003EПри лечении пациентов с нарушенной функцией почек или печени дозу аллопуринола необходимо снизить. У пациентов, получающих лечение по поводу артериальной гипертензии или сердечной недостаточности (например, пациенты, принимающие диуретики или ингибиторы АПФ), может наблюдаться сопутствующее нарушение функции почек, поэтому аллопуринол в этой группе пациентов следует использовать с осторожностью.\u003Cbr /\u003EБессимптомная гиперурикемия сама по себе не является показанием к применению аллопуринола. В таких случаях улучшение состояния пациентов может быть достигнуто благодаря изменениям в диете и потреблению жидкости наряду с устранением основной причины гиперурикемии.\u003Cbr /\u003EОстрый приступ подагры\u003Cbr /\u003EАллопуринол не следует применять до полного купирования острого приступа подагры, поскольку этим можно спровоцировать дополнительное обострение заболевания. Аналогично терапии урикозурическими средствами, начало лечения аллопуринолом может спровоцировать острый приступ подагры. Для того чтобы избежать этого осложнения, рекомендуется проводить профилактическую терапию нестероидными противовоспалительными препаратами или колхицином в течение по меньшей мере одного месяца до назначения аллопуринола. Подробные сведения о рекомендованных дозах, предостережениях и мерах предосторожности можно найти в соответствующей литературе.\u003Cbr /\u003EЕсли острый приступ подагры развивается на фоне терапии аллопуринолом, то прием препарата следует продолжить в той же дозе, а для лечения приступа необходимо назначить подходящее нестероидное противовоспалительное средство.\u003Cbr /\u003EОтложения ксантина\u003Cbr /\u003EВ случаях, когда образование мочевой кислоты значительно усилено (например, злокачественная опухолевая патология и соответствующая противоопухолевая терапия, синдром Леша-Найхана), абсолютная концентрация ксантина в моче в редких случаях может существенно увеличиться, что способствует отложению ксантина в тканях мочевых путей. Вероятность отложения ксантина в тканях можно свести к минимуму благодаря адекватной гидратации, которая обеспечивает оптимальное разведение мочи.\u003Cbr /\u003EВклинение конкрементов из мочевой кислоты\u003Cbr /\u003EАдекватная терапия аллопуринолом может приводить к растворению находящихся в почечных лоханках крупных конкрементов из мочевой кислоты однако, вероятность вклинения этих конкрементов в мочеточники невелика.\u003Cbr /\u003EГемохроматоз\u003Cbr /\u003EОсновной эффект аллопуринола при лечении подагры состоит в подавлении активности фермента ксантиноксидазы. Ксантиноксидаза может участвовать в уменьшении содержания и выведении железа, депонируемого в печени. Исследования, демонстрирующие безопасность терапии аллопуринолом в популяции больных гемохроматозом, отсутствуют. Пациентам с гемохроматозом, а также их кровным родственникам аллопуринол следует назначать с осторожностью.\u003Cbr /\u003EЛактоза\u003Cbr /\u003EКаждая 300 мг таблетка препарата Аллопуринол содержит 49 мг лактозы. Следовательно, этот препарат не должны принимать пациенты с редкой наследственной непереносимостью галактозы, недостаточностью лактазы и синдромом мальабсорбции глюкозы и галактозы."},{"name":"Взаимодействие","value":"При одновременном применении аллопуринол усиливает действие кумариновых антикоагулянтов, аденина арабинозида, а также гипогликемических препаратов (особенно при нарушениях функции почек).\u003Cbr\u003EУрикозурические средства и салицилаты в высоких дозах снижают активность аллопуринола.\u003Cbr\u003EПри одновременном применении аллопуринола и цитостатиков чаще проявляется миелотоксическое действие, чем при раздельном применении.\u003Cbr\u003EПри одновременном применении аллопуринола и азатиоприна или меркаптопурина наблюдается кумуляция последних в организме, т.к. в связи с ингибированием аллопуринолом активности ксантиноксидазы, необходимой для биотрансформации лекарственных средств, замедляется их метаболизм и элиминация."},{"name":"Регистрационный номер","value":"ЛСР-001485/08\nЛП-003429"},{"name":"Дата государственной регистрации","value":"19.03.2018\n26.01.2021"},{"name":"Владелец регистрационного удостоверения","value":"Органика"},{"name":"Изготовитель","value":"Органика"},{"name":"Фасовщик","value":"Органика"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Аллопуринол"},{"name":"Срок годности","value":"60 мес."}]}],"transitionId":"tr_18231150619185026726"}}}}
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повышением содержания мочевой кислоты в крови, в т.ч. при различных гематобластозах (остром лейкозе, хроническом миелолейкозе, лимфосаркоме и др.), при цитостатической и лучевой терапии опухолей (в т.ч. у детей), псориазе, обширных травматических повреждениях, вследствие ферментных нарушений (синдром Леша-Нихена), а также при массивной терапии глюкокортикостероидами, когда вследствие интенсивного распада тканей значительно повышается количество пуринов в крови.\u003Cbr /\u003EМочекислая нефропатия с нарушением функции почек (почечная недостаточность). Рецидивирующие смешанные оксалатно-кальциевые почечные камни (при наличии урикозурии)."},{"description":"","filters":[{"id":15768002,"name":"Противопоказания"}],"isMainProperty":false,"name":"Противопоказания","value":"Гиперчувствительность к аллопуринолу или любому другому компоненту препарата; печеночная недостаточность; тяжелая почечная недостаточность (стадия азотемии); первичный (идиопатический) гемохроматоз; бессимптомная гиперурикемия, острый приступ подагры; непереносимость лактозы, дефицит лактазы, синдром глюкозо- галактозной мальабсорбции; беременность, период грудного вскармливания, детский возраст до 3 лет."},{"description":"","filters":[{"id":15768292,"name":"Состав"}],"isMainProperty":false,"name":"Состав","value":"1 таблетка дозировки 100 мг препарата содержит:\u003Cbr /\u003Eактивное вещество: аллопуринол - 100 мг;\u003Cbr /\u003Eвспомогательные вещества: сахароза (сахар-песок рафинированный) - 20 мг, крахмал картофельный - 77,68 мг, магния стеарат (магний стеариновокислый) - 1 мг, желатин пищевой -1,32 мг.\u003Cbr /\u003E1 таблетка дозировки 300 мг препарата содержит:\u003Cbr /\u003Eактивное вещество: аллопуринол - 300 мг;\u003Cbr /\u003Eвспомогательные вещества: лактозы моногидрат (сахар молочный) - 49 мг; целлюлоза микрокристаллическая - 20 мг; карбоксиметилкрахмал натрия (примогель) - 20 мг; желатин пищевой - 5 мг; магния стеарат - 4 мг; кремния диоксид коллоидный (аэросил) - 2 мг."},{"description":"","filters":[{"id":27144131,"name":"Действующее вещество"}],"isMainProperty":false,"name":"Действующее вещество","value":"Аллопуринол"},{"description":"","filters":[{"id":15768000,"name":"Способ применения и дозы"}],"isMainProperty":false,"name":"Способ применения и дозы","value":"Внутрь. Препарат следует принимать один раз в день после еды, запивая большим количеством воды. Если суточная доза превышает 300 мг или наблюдаются симптомы непереносимости со стороны желудочно-кишечного тракта, то дозу необходимо делить на несколько приемов.\u003Cbr /\u003EДля осуществления начальной терапии следует применять аллопуринол в иных дозировках (100 мг) один раз в день. Если этой дозы недостаточно для того, чтобы должным образом снизить концентрацию мочевой кислоты в сыворотке крови, то суточную дозу препарата можно постепенно увеличивать до достижения желаемого эффекта. Следует проявлять особую осторожность при нарушении функции почек.\u003Cbr /\u003EПри повышении дозы аллопуринола каждые 1-3 недели необходимо определять концентрацию мочевой кислоты в сыворотке крови.\u003Cbr /\u003EРекомендованная доза препарата составляет 300-600 мг в сутки при среднетяжелом течении; 600-900 мг в сутки при тяжелом течении. Максимальная суточная доза - 900 мг. Рекомендованная доза для детей от 3 до 10 лет - по 5-10 мг/кг/сутки.\u003Cbr /\u003EРекомендованная доза для детей от 10 до 15 лет составляет 10-20 мг/кг/сутки. Суточная доза препарата не должна превышать 400 мг.\u003Cbr /\u003EАллопуринол редко применяется для детской терапии. Исключение составляют злокачественные онкологические заболевания (особенно лейкозы) и некоторые ферментативные нарушения (например, синдром Леша-Найхана).\u003Cbr /\u003EПоскольку аллопуринол и его метаболиты выводятся из организма почками, нарушение функции почек может приводить к задержке препарата и его метаболитов в организме с последующим удлинением периода полувыведения этих соединений из плазмы крови.\u003Cbr /\u003EАллопуринол и его производные удаляются из организма при помощи гемодиализа. Если сеансы гемодиализа проводятся 2-3 раза в неделю, то целесообразно определить необходимость перехода на альтернативный режим терапии - прием 300-400 мг аллопуринола сразу после завершения сеанса гемодиализа (между сеансами гемодиализа препарат не принимается).\u003Cbr /\u003EДля коррекции дозы препарата необходимо с оптимальными интервалами оценивать концентрацию солей мочевой кислоты в сыворотке крови, а также концентрацию мочевой кислоты и уратов в моче."},{"description":"","filters":[{"id":15767998,"name":"Побочные действия"}],"isMainProperty":false,"name":"Побочные действия","value":"Со стороны сердечно-сосудистой системы: в единичных случаях - артериальная гипертензия, брадикардия.\u003Cbr\u003EСо стороны пищеварительной системы: возможны диспептические явления (в т.ч. тошнота, рвота), диарея, транзиторное повышение активности трансаминаз в сыворотке крови; редко - гепатит; в единичных случаях - стоматит, нарушения функции печени (преходящее повышение активности трансаминаз и ЩФ), стеаторея.\u003Cbr\u003EСо стороны ЦНС и периферической нервной системы: в единичных случаях - слабость, повышенная утомляемость, головная боль, головокружение, атаксия, сонливость, депрессия, кома, парезы, парестезии, судороги, невропатии, нарушения зрения, катаракта, изменения сосочка зрительного нерва, нарушения вкусовых ощущений.\u003Cbr\u003EСо стороны системы кроветворения: в отдельных случаях - тромбоцитопения, агранулоцитоз и апластическая анемия, лейкопения (наиболее вероятны у больных с нарушениями функции почек).\u003Cbr\u003EСо стороны мочевыделительной системы: редко - интерстициальный нефрит; в единичных случаях - отеки, уремия, гематурия.\u003Cbr\u003EСо стороны эндокринной системы: в единичных случаях - бесплодие, импотенция, гинекомастия, сахарный диабет.\u003Cbr\u003EСо стороны обмена веществ: в единичных случаях - гиперлипидемия.\u003Cbr\u003EАллергические реакции: кожная сыпь, гиперемия, зуд; в отдельных случаях - ангиоиммунобластная лимфаденопатия, артралгия, повышение температуры, эозинофилия, лихорадка, синдром Стивенса-Джонсона, синдром Лайелла.\u003Cbr\u003EДерматологические реакции: в единичных случаях - фурункулез, алопеция, обесцвечивание волос."},{"description":"","filters":[{"id":15768001,"name":"Фармакологическое действие"}],"isMainProperty":false,"name":"Фармакологическое действие","value":"Аллопуринол является структурным аналогом гипоксантина. Аллопуринол, а также его основной активный метаболит - оксипуринол, ингибируют ксантиноксидазу - фермент, обеспечивающий преобразование гипоксантина в ксантин, и ксантина в мочевую кислоту.\nАллопуринол уменьшает концентрацию мочевой кислоты как в сыворотке крови, так и в моче. Тем самым он предотвращает отложение кристаллов мочевой кислоты в тканях и (или) способствует их растворению. Помимо подавления катаболизма пуринов у некоторых (но не у всех) пациентов с гиперурикемией, большое количество ксантина и гипоксантина становится доступно для повторного образования пуриновых оснований, что приводит к угнетению биосинтеза пуринов de novo по механизму обратной связи, что опосредовано угнетением фермента гипоксантин-гуанин фосфорибозил-трансферазы. Другие метаболиты аллопуринола - аллопуринол-рибозид и оксипуринол-7 рибозид."},{"description":"","filters":[{"id":34045110,"name":"Фармакологическая группа"}],"isMainProperty":false,"name":"Фармакологическая группа","value":"противоподагрическое средство - ксантиноксидазы ингибитор."},{"description":"","filters":[{"id":27141511,"name":"Форма выпуска для карточки"}],"isMainProperty":false,"name":"Форма выпуска","value":"таблетки"},{"description":"","filters":[{"id":35947170,"name":"Способ применения/введения"}],"isMainProperty":false,"name":"Способ применения/введения","value":"пероральный"},{"description":"","filters":[{"id":23679511,"name":"Минимальный возраст применения"},{"id":16082123,"name":"С рождения"}],"isMainProperty":false,"name":"Минимальный возраст применения","value":"от 3 лет"}]},{"name":"Дополнительно","specs":[{"description":"","filters":[{"id":15767999,"name":"Условия хранения"}],"isMainProperty":false,"name":"Условия хранения","value":"Хранить в защищенном от света месте, при температуре не выше 30 °С. Хранить в недоступном для детей месте."},{"description":"","filters":[{"id":15768014,"name":"Передозировка"}],"isMainProperty":false,"name":"Передозировка","value":"Симптомы: тошнота, рвота, диарея, головокружение, олигурия. Большинство симптомов передозировки аллопуринола могут ослабляться за счет повышения его почечной экскреции при обильном потреблении жидкости и соответственном усилении диуреза. Лечение: форсированный диурез; аллопуринол и его метаболиты выводятся при гемодиализе и перитонеальном диализе."},{"description":"","filters":[{"id":15768015,"name":"Применение при беременности и кормлении грудью"}],"isMainProperty":false,"name":"Применение при беременности и кормлении грудью","value":"Аллопуринол во время беременности следует принимать только по назначению врача и только при отсутствии терапевтической альтернативы, когда заболевание представляет больший риск для плода и матери, чем аллопуринол. При необходимости применения аллопуринола в период лактации следует решить вопрос о прекращении грудного вскармливания или воздержаться от назначения препарата."},{"description":"","filters":[{"id":17360993,"name":"Влияние на способность управлять транспортом и механизмами"}],"isMainProperty":false,"name":"Влияние на способность управлять транспортом и механизмами","value":"С осторожностью применять у пациентов, деятельность которых требует высокой концентрации внимания и быстрых психомоторных реакций."},{"description":"","filters":[{"id":15771167,"name":"Особые указания"}],"isMainProperty":false,"name":"Особые указания","value":"С осторожностью:\u003Cbr /\u003EПочечная недостаточность, хроническая сердечная недостаточность, сахарный диабет, артериальная гипертензия, нарушения функции печени, гипотиреоз, пожилой возраст.\u003Cbr /\u003EПациенты, принимающие ингибиторы ангиотензинпревращающего фермента (АПФ) или диуретики.\u003Cbr /\u003EДетский возраст до 15 лет (назначают только во время цитостатической терапии лейкозов и др. злокачественных заболеваний, а также симптоматического лечения ферментных нарушений).\u003Cbr\u003EСиндром лекарственного гиперчувствительности. ССД и ТЭН\u003Cbr /\u003EНа фоне применения аллопуринола поступали сообщения о развитии угрожающих жизни реакций со стороны кожи, такие как синдром Стивенса-Джонсона и токсический эпидермальный некролиз (ССД/ТЭН). Пациентов следует информировать о симптомах этих реакций (прогрессирующая кожная сыпь, часто с пузырьками и поражением слизистых) и тщательно мониторировать их развитие. Наиболее часто ССД/ТЭН развиваются на первых неделях приема препарата. При наличии признаков и симптомов ССД/ТЭН препарат Аллопуринол следует немедленно отменить и более не назначать! Манифестация реакций гиперчувствительности к аллопуринолу может быть самой различной, включая макулопапулезную экзантему, синдром лекарственной гиперчувствительности (DRESS) и ССД/ТЭН. Эти реакции являются клиническим диагнозом и их клинические проявления служат основой для принятия соответствующих решений. Терапию препаратом Аллопуринол следует немедленно прекратить при появлении кожной сыпи или других проявлений реакции гиперчувствительности. Нельзя возобновлять терапию у пациентов с синдромом гиперчувствительности и ССД/ТЭН. Кортикостероиды могут применяться для лечения кожных реакций при гиперчувствительности.\u003Cbr /\u003EХроническое нарушение функции почек\u003Cbr /\u003EПациенты с хроническим нарушением функции почек имеют больший риск развития реакций гиперчувствительности, связанных с аллопуринолом, в том числе и ССД/ТЭН.\u003Cbr /\u003EАллель HLA-B*5801\u003Cbr /\u003EБыло установлено, что присутствие аллеля HLA-B*5801 связано с развитием синдрома гиперчувствительности к аллопуринолу и ССД/ТЭН. Частота присутствия аллеля HLA- В*5801 различна в разных этнических группах и может достигать 20% в популяции китайцев Хань, около 12 % у корейцев и 1-2% у японцев и европейцев. Применение генотипирования для принятия решений о терапии аллопуринолом не исследовалось. Если известно, что пациент является носителем аллеля HLA-B*5801, то аллопуринол следует назначать только, если польза лечения превосходит риск. Следует очень внимательно следить за развитием синдрома гиперчувствительности и ССД/ТЭН. Пациент должен быть проинформирован о необходимости немедленной отмены лечения при первом появлении таких симптомов.\u003Cbr /\u003EНарушение функции печени и почек\u003Cbr /\u003EПри лечении пациентов с нарушенной функцией почек или печени дозу аллопуринола необходимо снизить. У пациентов, получающих лечение по поводу артериальной гипертензии или сердечной недостаточности (например, пациенты, принимающие диуретики или ингибиторы АПФ), может наблюдаться сопутствующее нарушение функции почек, поэтому аллопуринол в этой группе пациентов следует использовать с осторожностью.\u003Cbr /\u003EБессимптомная гиперурикемия сама по себе не является показанием к применению аллопуринола. В таких случаях улучшение состояния пациентов может быть достигнуто благодаря изменениям в диете и потреблению жидкости наряду с устранением основной причины гиперурикемии.\u003Cbr /\u003EОстрый приступ подагры\u003Cbr /\u003EАллопуринол не следует применять до полного купирования острого приступа подагры, поскольку этим можно спровоцировать дополнительное обострение заболевания. Аналогично терапии урикозурическими средствами, начало лечения аллопуринолом может спровоцировать острый приступ подагры. Для того чтобы избежать этого осложнения, рекомендуется проводить профилактическую терапию нестероидными противовоспалительными препаратами или колхицином в течение по меньшей мере одного месяца до назначения аллопуринола. Подробные сведения о рекомендованных дозах, предостережениях и мерах предосторожности можно найти в соответствующей литературе.\u003Cbr /\u003EЕсли острый приступ подагры развивается на фоне терапии аллопуринолом, то прием препарата следует продолжить в той же дозе, а для лечения приступа необходимо назначить подходящее нестероидное противовоспалительное средство.\u003Cbr /\u003EОтложения ксантина\u003Cbr /\u003EВ случаях, когда образование мочевой кислоты значительно усилено (например, злокачественная опухолевая патология и соответствующая противоопухолевая терапия, синдром Леша-Найхана), абсолютная концентрация ксантина в моче в редких случаях может существенно увеличиться, что способствует отложению ксантина в тканях мочевых путей. Вероятность отложения ксантина в тканях можно свести к минимуму благодаря адекватной гидратации, которая обеспечивает оптимальное разведение мочи.\u003Cbr /\u003EВклинение конкрементов из мочевой кислоты\u003Cbr /\u003EАдекватная терапия аллопуринолом может приводить к растворению находящихся в почечных лоханках крупных конкрементов из мочевой кислоты однако, вероятность вклинения этих конкрементов в мочеточники невелика.\u003Cbr /\u003EГемохроматоз\u003Cbr /\u003EОсновной эффект аллопуринола при лечении подагры состоит в подавлении активности фермента ксантиноксидазы. Ксантиноксидаза может участвовать в уменьшении содержания и выведении железа, депонируемого в печени. Исследования, демонстрирующие безопасность терапии аллопуринолом в популяции больных гемохроматозом, отсутствуют. Пациентам с гемохроматозом, а также их кровным родственникам аллопуринол следует назначать с осторожностью.\u003Cbr /\u003EЛактоза\u003Cbr /\u003EКаждая 300 мг таблетка препарата Аллопуринол содержит 49 мг лактозы. 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    Цена 151 ₽
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  • Аллопуринол Авексима таб., 300 мг, 30 шт.
    ВАМ–8 %
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    Аллопуринол Авексима таб., 300 мг, 30 шт.

    Рейтинг товара: 4.9 из 5
    на основе 22 оценки
    Цена 199 ₽ вместо 216
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  • Нимесулид таб., 100 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-yxpz1j5dr6l/toggleWishlist":{"skuId":"101392588730","productId":453476060,"offerId":"_RUp34lINLV-SD-pi_i4_w","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ1puvi/3+ndRZEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcI3P2d2AEQur/g2/kCGOvL9Qcg59zBBw==","sign":"Jjk5U2RpMnqw+LUBfOyXDHCe6x8dm+JH2fNhRNxn1TE="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-yxpz1j5dr6l/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Нимесулид таб., 100 мг, 30 шт.

    Рейтинг товара: 4.8 из 5
    на основе 359 оценок
    Цена 90 ₽
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  • Ревмафлекс капс., 60 шт., нейтральный, 1 уп.
    –10 %
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    Ревмафлекс капс., 60 шт., нейтральный, 1 уп.

    Рейтинг товара: 4.6 из 5
    на основе 2186 оценок
    Цена 888 ₽ вместо 987
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  • Сирдалуд таб., 2 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-kldt4x4w9p/toggleWishlist":{"skuId":"228082363","productId":1422663513,"offerId":"falvuZCsDXwjwoi0ieje3w","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ1puvi/3+ndRZEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI2b6wpgUQu4XhbBiQ1aEFIOfcwQc=","sign":"eEtARIAHjEmCsBlCwo6xaPchbndUxOx15fE0qbKhG1k="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-kldt4x4w9p/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Сирдалуд таб., 2 мг, 30 шт.

    Рейтинг товара: 4.5 из 5
    на основе 29 оценок
    Цена 163 ₽
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  • Колхицин Лирка таб., 1 мг, 30 шт.
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    Колхицин Лирка таб., 1 мг, 30 шт.

    Рейтинг товара: 4.9 из 5
    на основе 67 оценок
    Цена 2 475 ₽
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  • Подагрель капс., 80 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-5bwsyugdlnw/toggleWishlist":{"skuId":"101646030423","productId":1736145162,"offerId":"2YiNfpPFEk9_S5sPmnb6KA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ1puvi/3+ndRZEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIivLtuwYQ16zN1PoCGJ7UoQUg59zBBw==","sign":"soaLi7HD3z59PTLKpmW2b5Q/2tcJho9CDKJbdqFgYjs="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-5bwsyugdlnw/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Подагрель капс., 80 мг, 30 шт.

    Рейтинг товара: 4.6 из 5
    на основе 18 оценок
    Цена 1 045 ₽
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  • Ибупрофен таб. п/о плен., 200 мг, 50 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-q99nqmwpb8o/toggleWishlist":{"skuId":"101392442741","productId":526201043,"offerId":"Bz2cgwMzQ25GMvFBbPcWbw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ1puvi/3+ndRZEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcI0+H0+gEQ9crX2/kCGPuWkAcg59zBBw==","sign":"ShxngSZX13d9j4sK6GiGsxQKR3gKHyawwhnzMjL20O0="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-q99nqmwpb8o/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Ибупрофен таб. п/о плен., 200 мг, 50 шт.

    Рейтинг товара: 4.9 из 5
    на основе 136 оценок
    Цена 56 ₽
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  • Толперизон органика таб. п/о плен., 50 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-kmz1mwb6ohl/toggleWishlist":{"skuId":"101768994889","productId":1755934730,"offerId":"b-dmErPANkted0T1WHksqA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ1puvi/3+ndRZEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIiuClxQYQycCej/sCGJXd0Acg59zBBw==","sign":"+tUEu+fk1EIimbzbjGOpSZJ3BB1K6YkgFxnV5nAFESM="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-kmz1mwb6ohl/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Толперизон органика таб. п/о плен., 50 мг, 30 шт.

    Рейтинг товара: 4.8 из 5
    на основе 12 оценок
    Цена 152 ₽
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  • Фулфлекс капс., 0.3 г, 24 шт., 1 уп.
    –27 %
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    Фулфлекс капс., 0.3 г, 24 шт., 1 уп.

    Рейтинг товара: 4.8 из 5
    на основе 37 оценок
    Цена 414 ₽ вместо 564
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  • Коллаген для суставов капс., 120 шт.
    –19 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-6jnmw5xi05a/toggleWishlist":{"skuId":"101963562741","productId":1822682681,"offerId":"9HFmfyeTmgHpvBAl7mCa-Q","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ1puvi/3+ndRZEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIudyP5QYQ9f2B7PsCGOjl1gog59zBBw==","sign":"XWw6HobLTErfGe/8e1lRSBnE5/WDZKsM6pgBL01Sm/o="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-6jnmw5xi05a/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Коллаген для суставов капс., 120 шт.

    Рейтинг товара: 4.7 из 5
    на основе 664 оценки
    Цена 770 ₽ вместо 950
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Инструкция

Показания к применению

Заболевания, сопровождающиеся гиперурикемией (лечение и профилактика): подагра (первичная и вторичная), мочекаменная болезнь (с образованием уратов).
Гиперурикемия (первичная и вторичная), возникающая при заболеваниях, сопровождающихся усиленным распадом нуклеопротеидов и повышением содержания мочевой кислоты в крови, в т.ч. при различных гематобластозах (остром лейкозе, хроническом миелолейкозе, лимфосаркоме и др.), при цитостатической и лучевой терапии опухолей (в т.ч. у детей), псориазе, обширных травматических повреждениях, вследствие ферментных нарушений (синдром Леша-Нихена), а также при массивной терапии глюкокортикостероидами, когда вследствие интенсивного распада тканей значительно повышается количество пуринов в крови.
Мочекислая нефропатия с нарушением функции почек (почечная недостаточность). Рецидивирующие смешанные оксалатно-кальциевые почечные камни (при наличии урикозурии).

Противопоказания

Гиперчувствительность к аллопуринолу или любому другому компоненту препарата; печеночная недостаточность; тяжелая почечная недостаточность (стадия азотемии); первичный (идиопатический) гемохроматоз; бессимптомная гиперурикемия, острый приступ подагры; непереносимость лактозы, дефицит лактазы, синдром глюкозо- галактозной мальабсорбции; беременность, период грудного вскармливания, детский возраст до 3 лет.

Способ применения и дозы

Внутрь. Препарат следует принимать один раз в день после еды, запивая большим количеством воды. Если суточная доза превышает 300 мг или наблюдаются симптомы непереносимости со стороны желудочно-кишечного тракта, то дозу необходимо делить на несколько приемов.
Для осуществления начальной терапии следует применять аллопуринол в иных дозировках (100 мг) один раз в день. Если этой дозы недостаточно для того, чтобы должным образом снизить концентрацию мочевой кислоты в сыворотке крови, то суточную дозу препарата можно постепенно увеличивать до достижения желаемого эффекта. Следует проявлять особую осторожность при нарушении функции почек.
При повышении дозы аллопуринола каждые 1-3 недели необходимо определять концентрацию мочевой кислоты в сыворотке крови.
Рекомендованная доза препарата составляет 300-600 мг в сутки при среднетяжелом течении; 600-900 мг в сутки при тяжелом течении. Максимальная суточная доза - 900 мг. Рекомендованная доза для детей от 3 до 10 лет - по 5-10 мг/кг/сутки.
Рекомендованная доза для детей от 10 до 15 лет составляет 10-20 мг/кг/сутки. Суточная доза препарата не должна превышать 400 мг.
Аллопуринол редко применяется для детской терапии. Исключение составляют злокачественные онкологические заболевания (особенно лейкозы) и некоторые ферментативные нарушения (например, синдром Леша-Найхана).
Поскольку аллопуринол и его метаболиты выводятся из организма почками, нарушение функции почек может приводить к задержке препарата и его метаболитов в организме с последующим удлинением периода полувыведения этих соединений из плазмы крови.
Аллопуринол и его производные удаляются из организма при помощи гемодиализа. Если сеансы гемодиализа проводятся 2-3 раза в неделю, то целесообразно определить необходимость перехода на альтернативный режим терапии - прием 300-400 мг аллопуринола сразу после завершения сеанса гемодиализа (между сеансами гемодиализа препарат не принимается).
Для коррекции дозы препарата необходимо с оптимальными интервалами оценивать концентрацию солей мочевой кислоты в сыворотке крови, а также концентрацию мочевой кислоты и уратов в моче.
Полная инструкция
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Аллопуринол таб.
Аллопуринол таб., 100 мг, 50 шт.
5.0
(27)
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Инструкция

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–11 %
Вместо:157 ₽
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5.0
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У продавца:27 оценок·3 отзыва
У всех продавцов:200 оценок·61 отзыв
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user avatar
4 месяца назад • Лариса Рыбакова • Куплен на Маркете
Комментарий: Пью от подагры, очень высокий уровень мочевой кислоты. За 3 месяца регулярного приёма снизила показатель вдвое. Результатом довольна.
user avatar
7 месяцев назад • Юрий Попов • Куплен на Маркете
Достоинства: Жене помогает
Недостатки: Нет
Комментарий: Жене этот препарат необходим
user avatar
6 месяцев назад • Elena K. • Куплен на Маркете
Достоинства: недорогой
Комментарий: давно принимаю данный препарат. нареканий нет
Посмотреть все отзывы на Маркете
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Рекомендуем

  • Бисопролол Канон таб. п/о плен., 5 мг, 30 шт.
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    Бисопролол Канон таб. п/о плен., 5 мг, 30 шт.

    Цена 99 ₽
  • Омепразол капс., 20 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1400799622_1/content/content/gallery":{"title":"Омепразол капс., 20 мг, 30 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/4580278/img_id9062277251401801626.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4580278/img_id9062277251401801626.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4580278/img_id9062277251401801626.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4580278/img_id9062277251401801626.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4580278/img_id9062277251401801626.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4580278/img_id9062277251401801626.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4219828/img_id4616058566707128396.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4219828/img_id4616058566707128396.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4219828/img_id4616058566707128396.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4219828/img_id4616058566707128396.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4219828/img_id4616058566707128396.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4219828/img_id4616058566707128396.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/6425823/img_id7244626295602644969.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/6425823/img_id7244626295602644969.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/6425823/img_id7244626295602644969.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/6425823/img_id7244626295602644969.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/6425823/img_id7244626295602644969.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/6425823/img_id7244626295602644969.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4466970/img_id3053171073301595904.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4466970/img_id3053171073301595904.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4466970/img_id3053171073301595904.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4466970/img_id3053171073301595904.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4466970/img_id3053171073301595904.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4466970/img_id3053171073301595904.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ1puvi/3+ndRZEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIVCIaD+psFEKTI5mwY5KTVByDa2cEH","sign":"zJgxBfDJHvvRmBdH/zsk73rK+1JodblYa+E9aOx4KrE="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1400799622_1/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
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    Омепразол капс., 20 мг, 30 шт.

    Цена 37 ₽
  • Милурит таб., 100 мг, 50 шт.
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    Цена 151 ₽
  • Розувастатин-СЗ таб. п/о плен., 20 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1401075427_3/content/content/toggleWishlist":{"skuId":"186910723","productId":1401075427,"offerId":"-y81h-Lkpjhgdkj6cGXT2A","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ1puvi/3+ndRZEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIVCOPtipwFEIOQkFkYrt7QByDX3MEH","sign":"2mE8zkkwb4Kj9ohSA28AzjuydSNQBMjVSupKfAmjqxw="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1401075427_3/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Розувастатин-СЗ таб. п/о плен., 20 мг, 30 шт.

    Цена 292 ₽
  • Спиронолактон таб., 25 мг, 20 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778174072_4/content/content/gallery":{"title":"Спиронолактон таб., 25 мг, 20 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/5146425/img_id1356883768054747447.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5146425/img_id1356883768054747447.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5146425/img_id1356883768054747447.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5146425/img_id1356883768054747447.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5146425/img_id1356883768054747447.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5146425/img_id1356883768054747447.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/1514097/img_id269241345773855956.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/1514097/img_id269241345773855956.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/1514097/img_id269241345773855956.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/1514097/img_id269241345773855956.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/1514097/img_id269241345773855956.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/1514097/img_id269241345773855956.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ1puvi/3+ndRZEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIVCPiQ888GEPGT4GwYhKmyCCDX3MEH","sign":"+BCls2tgvc5+O9l4ETr269K5hfiMM494khTPucMOIk0="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778174072_4/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778174072_4/content/content/toggleWishlist":{"skuId":"228067825","productId":1778174072,"offerId":"xUZo9X8ZtzVUby-GmKyb0g","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ1puvi/3+ndRZEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIVCPiQ888GEPGT4GwYhKmyCCDX3MEH","sign":"+BCls2tgvc5+O9l4ETr269K5hfiMM494khTPucMOIk0="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778174072_4/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Спиронолактон таб., 25 мг, 20 шт.

    Цена 82 ₽
  • Аллопуринол Авексима таб., 300 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1767458007_5/content/content/toggleWishlist":{"skuId":"101807281637","productId":1767458007,"offerId":"MFgyqpiUkBt5AjwpyQc7ng","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ1puvi/3+ndRZEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIXCNeJ5coGEOWrv6H7AhjUqdgHIOfcwQc=","sign":"8JBlA3vOTFSIKbcpNOGPygbqLUQ+PKBSqTPhqHqKTn4="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1767458007_5/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Аллопуринол Авексима таб., 300 мг, 30 шт.

    Цена 199 ₽ вместо 216
  • Нимесулид таб., 100 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:453476060_6/content/content/gallery":{"title":"Нимесулид таб., 100 мг, 30 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/3934197/img_id8777084924075638678.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/3934197/img_id8777084924075638678.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/3934197/img_id8777084924075638678.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/3934197/img_id8777084924075638678.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/3934197/img_id8777084924075638678.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/3934197/img_id8777084924075638678.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/5163855/img_id2657117981474543699.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5163855/img_id2657117981474543699.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5163855/img_id2657117981474543699.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5163855/img_id2657117981474543699.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5163855/img_id2657117981474543699.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5163855/img_id2657117981474543699.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ1puvi/3+ndRZEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIXCNz9ndgBELq/4Nv5Ahjry/UHIOfcwQc=","sign":"R/DYBoXLe+c7QgkIS69GSH4CagmZmLqlDukXk1Qx7mg="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:453476060_6/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:453476060_6/content/content/toggleWishlist":{"skuId":"101392588730","productId":453476060,"offerId":"_RUp34lINLV-SD-pi_i4_w","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ1puvi/3+ndRZEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIXCNz9ndgBELq/4Nv5Ahjry/UHIOfcwQc=","sign":"R/DYBoXLe+c7QgkIS69GSH4CagmZmLqlDukXk1Qx7mg="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:453476060_6/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Нимесулид таб., 100 мг, 30 шт.

    Цена 90 ₽
  • Ревмафлекс капс., 60 шт., нейтральный, 1 уп.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778175162_7/content/content/gallery":{"title":"Ревмафлекс капс., 60 шт., нейтральный, 1 уп.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/5235182/img_id7240902984627641170.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5235182/img_id7240902984627641170.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5235182/img_id7240902984627641170.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5235182/img_id7240902984627641170.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5235182/img_id7240902984627641170.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5235182/img_id7240902984627641170.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/1927422/img_id7935672565540282125.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/1927422/img_id7935672565540282125.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/1927422/img_id7935672565540282125.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/1927422/img_id7935672565540282125.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/1927422/img_id7935672565540282125.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/1927422/img_id7935672565540282125.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ1puvi/3+ndRZEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCLqZ888GELmypb4CGNW7oQYg59zBBw==","sign":"8u75/9XyPef/xLdwJ+Fm2xI7CSoItDF9CQYHuIHui2o="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778175162_7/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778175162_7/content/content/toggleWishlist":{"skuId":"667507001","productId":1778175162,"offerId":"WF7YFX1FYF8C0EIlKjCsdw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ1puvi/3+ndRZEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCLqZ888GELmypb4CGNW7oQYg59zBBw==","sign":"8u75/9XyPef/xLdwJ+Fm2xI7CSoItDF9CQYHuIHui2o="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778175162_7/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Ревмафлекс капс., 60 шт., нейтральный, 1 уп.

    Цена 888 ₽ вместо 987
  • Реклама
    {"widgets":{"@light/AdLabel":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_101_8/content/content/content/adLabel":{"adLabel":{"adLabelText":"Реклама","advertizer":"ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ \"МИДЕА ОНЛАЙН\", ИНН 9715309509, ID #e-1g-10541-VND-ADV","adLabel":1},"advertisementId":1684621,"allowDebug":false,"borderRadius":5,"indents":6}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_101_8/content/content/content/adLabel":{"name":"@light/AdLabel"}}}
    {"widgets":{"@marketfront/CreativeBanner":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_101_8/content/content/content":{"cpcLink":"/safeclick/data=SpQw45JhDGEtO5qMksCMdCT6PbT1wOtXqPHe_TGGhRPnakkXd4kgVcawy6R68fLtVfksDxCxzDfa8kLfATp1k8Nye0PQ1QIhihp6d4wRicW2ptHs2gpS5TNjH6nFBd9if8Bccf5ngpMDz1y1gq7oBgucWbkeG5TfkgiFKwErA-1aBAJ0H3okZck7HJl_bIjqUd176KvaK2fuPdkBgRMoMYoo3LYYJ67W10ovod35L4hBeOzIqiUezTz4j4xiHiaLH-biamD0swf-Wroic4ETeN95nnNuB-9Xb23UOPQGqQk73B9_HrUgs4En5TTzyhaoxxlyravOhkm4fBPGNhEFNYq7E25tJpUMmB0YQO1ybKDcZjV2imXpXbCIRrbxfhcIWDIBijN9ts8otKW3cc-98QoLlDgmBfywL34GEL6i3ZSSd9DGR8voqAHF8NBicpesNm9lnFtDr_r7k7ouc_poodVE_QvdRQzTAoGsk-LsD2zkFBAicRwkIMYZWG1YUofgMGNkENbbDzDWoLZxd6ue1A9eWx2pjy6TrHu2bJPg3oHqihgbnZxU9fe4jr-xIFBxEoKBoHgCApJY_8Ik48VwuV5t21xeXfpgAodFRl2Zqob4SX4K8tE5D6Ryo76yIxjLBiczOiix55AQHoHSaJ5CFtWpZxKvQwKHH5gkDrEiORjMffaBoiM9DGXLf9L7glvy_ixtn0xJa0mPWB4fE8bh2U_1tkvsuD0oAXCg5tVfuXF63oOz-dSeCn4W0w9-ttqVQgDK3oi3W3N5SdtLbct-MVmUlRbF2NnrV67USSIrTgy320i5BPn3ZdvU96QNTa_bZqkTguHh8JGhQRf5zpreZBbywT8cShiuJT65KchSIjiSELOHytUH-t-tDkoGGXVGYEd7Y4yhtiB8jyC4rKtXyUzU5eXQbf2VKK565aVDgqGpfRi919b1jE3YJJMoNcyivb-GAUcqwmG0GLRBe-cT3VsfDA-I5f28RhAPc6zdOc2-AWejayvZgbfmBmT6zgbdPg0_3VjkDHvPxNEACzKL1d5x5YM85KsgDNx0oII_cwZWnprSortrYJV11EllrQgTc2X-eTPQiZZHt1rc5z015kRuFn3OQ-FXwUwkrz2eE5FEpKrIy3_h27o7hGuHRt-eTMyFL9fmO28CnLTXmcWG_oXIY3RQeJPjNgyaRxfcU1DeEyjvi62vH0X4F6C9KQeZNhhj2yIRcNiKhUFYAag_mQyBqtHZ5i-YJxmmEmqH7QATLxfGBnmcEbNoM9hSJVN0RGElEfVpift916HLTd1DqMZKXE-_VNDl5RWQT6HD9Y9tu38N0a-JVZsOV1gBXRGEzhKqBFzSnbSiFdz7c-LaIlr7CYHSQgGlNcFhhPZkAEZXB1fk4tueTY4sfXRs6KfA8cICZT7TbZThW9P9zgjo3tor94xOG05HyhdHU11-HZ8QwBtqHR-kvKRuv1oY0tMx_RWC-Zu8vquIgJPQvmEqT0NnCJKrNrI3tMHhdICx0W7rXoZjF-w0XN0ynAbyp3DI-POop_HXVFqOQKMigYy683N6i06zw9wrvAGkvRPLIQqV8hQvbgOr8xznJfgEf1sBE2vfaaI_3E7-Qkg-5pnSAPsxovOx6FY01vc2T43pv43foTtkpJ1r-pg3KAjDWxxGXQRPD3h264SS0_t--9veTm-81AUZX9W90aGa6x9H_zdeagWpfj5iNUwdAqe650hCWcF0OQWJ-e5KfBrTp0eRsqTgNtVRuP28RI1T5Sht8leF4B3Uj7zHGIsMBvQIIis5mfA060MKglCNvxCi2oMR_C11dcr5Web4mSdLA7HGf04_qkpZyRGc3Kla5C204ssC62qKhApnGnY8lXLH-z2cC5dEOrPxSuiZxujbboZWEGpll3mOcWnr6gm7dQZrdnmgxnj_Ervy_7FHGoFsJnB3oIqYu09R-KQYC37uuupRLDDxgfR_wxe3jajq0ksF9D8E5twRH9TwBpGMvHf8db-onPkBlPUJY8G9MYxfL6xWW7JvkLAAc9YZwpNaR8jpMbXYZgtwbEw6pxwPf0xPQS3eFqlJzx7J099G-pelrLvuisarg0xqgjJ6WWSqk4ob2JWqx0wLOBgYqTZCGBBosyApUny1MpgjXw1IZAwzvCbktaZhsqhQg-UAm2P8DpGS30WLJ8lw8CcZELovAVXXJs0KilNOJsKCO4wOA90CiKyxcBuMstswCYSUwAPoTe_lQ6st7wTloC7nMFC2ZA6JrmdFDcnJBkZssBkCrFO8zXyhJoDQxQfAxRFRnDYNinosrYDbKIxfXmjfvs7ASXm9XUF-EQegK-M78VSWT4CKN0nx4mSLYF99HTwQgIJaD55mDNiVT1s4Fy7G429IPfRgy8F4tsbcUcB_y2SjIRNeuYnPMUAwUinEnbay0kX4GLtmPI9E51Z5FsFawRHEeRuy1deG2H_vLMWZd0olWT44VMZ22HjReEi83sGnZKi7h6Xha2eXmVFYQgf_cAFkRExWF9U0d-w4jJrehrFfjXso2kWBqDPmqfTge4sEiIGV_s7gebmKoIqbdcuJTdH9t60P1CE-0kyECm7XAi6XUxmZpZKMVRM8oLHBb7SvOuOTtnl43i7UGKhzIKsU83vDs9f3RW4UF3IsO0fLI9IvHftmQpPsyvDSf8-D2fNxTzRuJpxzEImCPsL_tpnMhwht9vhmCjtzAwel6PbPuz2A/b64e=1/sign=2bd6b598960d619dc1837f98b56b1c31/keyno=MARKET_1/*","url":"https://market.yandex.ru/special/midea-may24?fromSins=1&erid=nyi26TK8Sq2EHejwvBkWHhmQtZLvRLhj","isClickoutExternal":true,"src":"https://avatars.mds.yandex.net/get-market-adv/8282799/d7a258f8-c805-46ff-9794-3089022dd98b/470x762","srcSet":"https://avatars.mds.yandex.net/get-market-adv/8282799/d7a258f8-c805-46ff-9794-3089022dd98b/470x762 1x, https://avatars.mds.yandex.net/get-market-adv/8282799/d7a258f8-c805-46ff-9794-3089022dd98b/940x1524 2x","showUrl":"/safeclick/data=SpQw45JhDGE6zDtOdUQO_JMVMdThxNmdZ-ufZO_EpNEyRl7gpQc9-alHjsPdsp1kcibJIIrkTMOHi3kH2XpV1ZrGmBpF_hmkEoDVjTFvY1cMBVh96CpacH27tWegVYZUaLJhosbrlP9dItZbP1_086na1ONEpuSGOpQB_myd0BTN1eDUjZyv6MrsLMJQrEeA8M14RBuWBvP7VIhel7Bnqevvy6tP3Z4GZ8uNUy5hp3-78BylQmCnFR2FdFdWEpBNKq6iCu_0dHQWKal9a7DqzCZXBjH2NWEui92dIW6mtShIk7OXhBK5-F3pe4EwY3d9UmamFXbjJXyoFKwa73IyH0uKibplBOdK8i2QtC8EoLCUrinj0rKGutHhPlCgLeIZBZ7AUerF4bbqu6pjUFA6HoUFHB3OUjq0Hq0jpZDZpDWZE_DESPzxkVI2iNGAREhz5vYHd6h1Ara5RRfH_PECGy1mqu2aflXAho8tD9pHxMxNkW-Bg4q3s9PKk6QrfksBVJZB_ZhfscJDcPvNUYo73Q-HAe45fudQLv7QZeb9xcx4urr2OWKzfw-XtLn6mLBxyjHbpRgVMi8GIoiv7A9035GcnS4E2KgSteNA4-uAwxW7H-0YnZEtXWyyUr01vvSdreQS0WPX1kXQaarNl5gJCEOOAY60xm_BfugkFAsMrrjzSQ7eq18Y_S4d8jqMZAuv8kWL3NxcpUQIR8dn7r417GXCu15KqRHWtVSt0jTcgF7ril7Dyu1OfsYmWAr0a1k1OwXcV4Tm9bR1POAOue11-Q2Z7VdebIBlPwHV8eUEWO242wWvIyAE4h0BmJj8qH3oM8w5WWi_VGJIaGrbVyfnXjG0bnlrdhHT4PeyEWNICjjFFQ9_sUw8DsFh8QFuUKGxqR9FLoexilPLFxoQuwFXdXbuUrRXYCFP-4CgedS89DpuL8aCbhn1xmNoZO3DKpjq87nEPU_scQJg3cfl3NUzqlt2WwJUUiuRZtspkR5uag-6yxbDaJsemKqwAGwBslMDTsBDCbvKXBk,/b64e=1/sign=ba9fc7315d0d53df29d82dcebe076f0d/keyno=MARKET_1/*","roundedCorners":true,"advertisementId":1684621,"fixedRatio":false,"height":762,"width":470,"billingTargetId":"7c8d7j73wwq_1684621","creativeType":"Banner","position":8,"isWhole":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_101_8/content/content/content":{"name":"@marketfront/CreativeBanner"}}}
  • Сирдалуд таб., 2 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1422663513_9/content/content/toggleWishlist":{"skuId":"228082363","productId":1422663513,"offerId":"falvuZCsDXwjwoi0ieje3w","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ1puvi/3+ndRZEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIVCNm+sKYFELuF4WwYkNWhBSDn3MEH","sign":"wcPk43vZPG2IMvPaQmQ87umFagrEah9QlUaa6ROR+b8="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1422663513_9/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Сирдалуд таб., 2 мг, 30 шт.

    Цена 163 ₽
  • Колхицин Лирка таб., 1 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1734845784_10/content/content/toggleWishlist":{"skuId":"101640945987","productId":1734845784,"offerId":"M3mIGK4c4GMetH6ASJAQIQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ1puvi/3+ndRZEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIXCNjKnrsGEMOCl9L6Ahjmv+kMIOfcwQc=","sign":"4yjO4exURdC1H5S+pZnAgpe9zB84rtqH0ik20wmvqYU="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1734845784_10/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Колхицин Лирка таб., 1 мг, 30 шт.

    Цена 2 475 ₽
  • Подагрель капс., 80 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1736145162_11/content/content/gallery":{"title":"Подагрель капс., 80 мг, 30 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/4867510/img_id6645997908473262951.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4867510/img_id6645997908473262951.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4867510/img_id6645997908473262951.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4867510/img_id6645997908473262951.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4867510/img_id6645997908473262951.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4867510/img_id6645997908473262951.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/5335973/img_id2261286156109126868.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5335973/img_id2261286156109126868.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5335973/img_id2261286156109126868.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5335973/img_id2261286156109126868.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5335973/img_id2261286156109126868.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5335973/img_id2261286156109126868.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ1puvi/3+ndRZEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIXCIry7bsGENeszdT6Ahie1KEFIOfcwQc=","sign":"ld0V2RnZyu3gF8Dyd51q8EEVV0bMJllShjYmIQAXtLo="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1736145162_11/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1736145162_11/content/content/toggleWishlist":{"skuId":"101646030423","productId":1736145162,"offerId":"2YiNfpPFEk9_S5sPmnb6KA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ1puvi/3+ndRZEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIXCIry7bsGENeszdT6Ahie1KEFIOfcwQc=","sign":"ld0V2RnZyu3gF8Dyd51q8EEVV0bMJllShjYmIQAXtLo="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1736145162_11/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Подагрель капс., 80 мг, 30 шт.

    Цена 1 045 ₽
  • Коллаген для суставов капс., 120 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1822682681_12/content/content/gallery":{"title":"Коллаген для суставов капс., 120 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/1865271/img_id4632324828079448171.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/1865271/img_id4632324828079448171.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/1865271/img_id4632324828079448171.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/1865271/img_id4632324828079448171.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/1865271/img_id4632324828079448171.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/1865271/img_id4632324828079448171.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/1246680/img_id1761964135721589838.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/1246680/img_id1761964135721589838.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/1246680/img_id1761964135721589838.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/1246680/img_id1761964135721589838.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/1246680/img_id1761964135721589838.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/1246680/img_id1761964135721589838.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/5275484/img_id3294270387438269122.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5275484/img_id3294270387438269122.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5275484/img_id3294270387438269122.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5275484/img_id3294270387438269122.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5275484/img_id3294270387438269122.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5275484/img_id3294270387438269122.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ1puvi/3+ndRZEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIXCLncj+UGEPX9gez7Ahjo5dYKIOfcwQc=","sign":"BTm9mVWOjkMOCkn83JoTPJr9SuMTgjy9P/g6/wkNJ28="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1822682681_12/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1822682681_12/content/content/toggleWishlist":{"skuId":"101963562741","productId":1822682681,"offerId":"9HFmfyeTmgHpvBAl7mCa-Q","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ1puvi/3+ndRZEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIXCLncj+UGEPX9gez7Ahjo5dYKIOfcwQc=","sign":"BTm9mVWOjkMOCkn83JoTPJr9SuMTgjy9P/g6/wkNJ28="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1822682681_12/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Коллаген для суставов капс., 120 шт.

    Цена 770 ₽ вместо 950
  • Ибупрофен таб. п/о плен., 200 мг, 50 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:526201043_13/content/content/gallery":{"title":"Ибупрофен таб. п/о плен., 200 мг, 50 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/3732535/img_id4505606647312581795.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/3732535/img_id4505606647312581795.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/3732535/img_id4505606647312581795.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/3732535/img_id4505606647312581795.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/3732535/img_id4505606647312581795.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/3732535/img_id4505606647312581795.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4119563/img_id8274329313053374035.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4119563/img_id8274329313053374035.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4119563/img_id8274329313053374035.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4119563/img_id8274329313053374035.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4119563/img_id8274329313053374035.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4119563/img_id8274329313053374035.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4441046/img_id4773743022344705486.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4441046/img_id4773743022344705486.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4441046/img_id4773743022344705486.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4441046/img_id4773743022344705486.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4441046/img_id4773743022344705486.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4441046/img_id4773743022344705486.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ1puvi/3+ndRZEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIXCNPh9PoBEPXK19v5Ahj7lpAHIOfcwQc=","sign":"Mt5emGjNg5FK1/JEIY1lRvycgn7j6L94PqJhso4RHXY="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:526201043_13/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
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    Ибупрофен таб. п/о плен., 200 мг, 50 шт.

    Цена 56 ₽
  • Толперизон органика таб. п/о плен., 50 мг, 30 шт.
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    Толперизон органика таб. п/о плен., 50 мг, 30 шт.

    Цена 152 ₽
  • Эгилок таб., 25 мг, 60 шт.
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    Эгилок таб., 25 мг, 60 шт.

    Цена 70 ₽
  • Бисопролол таб. п/о плен., 5 мг, 30 шт.
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    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1401075592_16/content/content/toggleWishlist":{"skuId":"228004076","productId":1401075592,"offerId":"9kyVvI7gZcH-bFX9LEdtxA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ1puvi/3+ndRZEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIVCIjvipwFEOyh3GwYtNWHBCDX3MEH","sign":"jFYWXVanlkGGBxqBf1YuIusLv9OVG0dH2f1opvEVD2M="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1401075592_16/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Бисопролол таб. п/о плен., 5 мг, 30 шт.

    Цена 105 ₽
  • Фулфлекс капс., 0.3 г, 24 шт., 1 уп.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778174704_17/content/content/gallery":{"title":"Фулфлекс капс., 0.3 г, 24 шт., 1 уп.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/5219306/img_id1896056410346478392.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5219306/img_id1896056410346478392.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5219306/img_id1896056410346478392.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5219306/img_id1896056410346478392.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5219306/img_id1896056410346478392.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5219306/img_id1896056410346478392.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 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217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4571152/img_id1128998031206416571.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4571152/img_id1128998031206416571.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4571152/img_id1128998031206416571.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4571152/img_id1128998031206416571.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4571152/img_id1128998031206416571.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4571152/img_id1128998031206416571.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/5220722/img_id1280126659248061459.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5220722/img_id1280126659248061459.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5220722/img_id1280126659248061459.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5220722/img_id1280126659248061459.jpeg/240x320 240w, 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    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778174704_17/content/content/toggleWishlist":{"skuId":"265150446","productId":1778174704,"offerId":"WWiRfsUCVTYjR7SwsxVBiQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ1puvi/3+ndRZEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIVCPCV888GEO6/t34Y2PrUByDn3MEH","sign":"tsSLmT0guglyjS/mMl22Y/yD5TUcBErwaLOGWMyTECQ="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778174704_17/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Фулфлекс капс., 0.3 г, 24 шт., 1 уп.

    Цена 414 ₽ вместо 564
  • Верошпирон таб., 25 мг, 20 шт.
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    Верошпирон таб., 25 мг, 20 шт.

    Цена 134 ₽
  • Ацетилсалициловая кислота-УБФ таб., 500 мг, 20 шт.
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    Ацетилсалициловая кислота-УБФ таб., 500 мг, 20 шт.

    Цена 28 ₽
  • Эдарби Кло таб. п/о плен., 40 мг+12.5 мг, 28 шт.
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    Эдарби Кло таб. п/о плен., 40 мг+12.5 мг, 28 шт.

    Цена 1 109 ₽
  • Реклама
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  • Лозартан таб. п/о плен., 100 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1401075610_22/content/content/gallery":{"title":"Лозартан таб. п/о плен., 100 мг, 30 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/4809526/img_id8395491917984463412.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4809526/img_id8395491917984463412.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4809526/img_id8395491917984463412.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4809526/img_id8395491917984463412.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4809526/img_id8395491917984463412.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4809526/img_id8395491917984463412.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/1928572/img_id5174426506517930169.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/1928572/img_id5174426506517930169.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/1928572/img_id5174426506517930169.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/1928572/img_id5174426506517930169.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/1928572/img_id5174426506517930169.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/1928572/img_id5174426506517930169.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ1puvi/3+ndRZEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIVCJrvipwFEImj3GwYhKmyCCDX3MEH","sign":"FicLWaKgRYlvWftpI7imBSAZrWmNFq5ffIFT2t6ARd8="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1401075610_22/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
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    Лозартан таб. п/о плен., 100 мг, 30 шт.

    Цена 167 ₽
  • Леркамен таб. п/о плен., 10 мг, 60 шт.
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    Леркамен таб. п/о плен., 10 мг, 60 шт.

    Цена 752 ₽
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