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Описание

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Анастрозол-Тева таб. п/о плен., 1 мг, 28 шт.

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5.0
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Коротко о товаре

Артикул Маркета
2101333042744
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
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мг, лактозы моногидрат (высушенный распылением) 23,0 мг, карбоксиметилкрахмал натрия, тип А 7,0 мг, магния стеарат 1,0 мг, опадрай белый 02G28619 (гипромеллоза Е464 1,8750 мг, титана диоксид Е171 0,6375мг, макрогол-6000 0,3000 мг, макрогол-400 0,1875 мг)."},{"name":"Действующее вещество","value":"Анастрозол","transition":{"type":"catalog","params":{"categorySlug":"protivoopukholevye-preparaty-i-immunomoduliatory","categoryId":"15756914","navnodeId":"72508","glfilters":["27144131:28708571"]}}},{"name":"Способ применения и дозы","value":"Внутрь. 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В качестве адъювантной терапии рекомендуемая продолжительность лечения - 5 лет.\u003Cbr\u003EНарушения функции почек: коррекция дозы у пациентов с нарушением функции почек не требуется.\u003Cbr\u003EНарушения функции печени: коррекция дозы у пациентов с легкой и умеренной степенью нарушения функции печени не требуется."},{"name":"Побочные действия","value":"Частота побочных реакций, приведенных ниже, определялась соответственно следующим критериям: очень часто (не менее 1/10); часто (более 1/100, менее 1/10), нечасто (более 1/1000, менее 1/100), редко - (более 1/10000, менее 1/1000); очень редко (менее 1/10000), включая отдельные сообщения.\u003Cbr\u003EСо стороны сосудов: очень часто - “приливы” крови к лицу.\u003Cbr\u003EСо стороны скелетно-мышечной и соединительной ткани: очень часто артралгия/скованность суставов, артрит; часто - боль в костях, миалгия; нечасто - триггерный палец.\u003Cbr\u003EСо стороны половых органов и молочной железы: часто - сухость слизистой оболочки влагалища, влагалищное кровотечение (в основном в течение первых недель после отмены или смены предшествующей гормональной терапии на анастрозол).\u003Cbr\u003EСо стороны кожи и подкожных тканей: очень часто - кожная сыпь; часто - истончение волос, алопеция, аллергические реакции; нечасто - крапивница; редко - мультиформная эритема, анафилактоидная реакция, кожный васкулит (включая отдельные случаи пурпуры (синдром Шенлейна-Геноха)); очень редко - синдром Стивенса-Джонсона, ангионевротический отек.\u003Cbr\u003EСо стороны желудочно-кишечного тракта: очень часто - тошнота; часто - диарея, рвота.\u003Cbr\u003EСо стороны печени и желчевыводящих путей: часто - повышение активности щелочной фосфатазы, аланинаминотрансферазы, аспартатаминотрансферазы; нечасто - повышение активности гамма-глутамил-трансферазы и концентрации билирубина, гепатит.\u003Cbr\u003EСо стороны нервной системы: очень часто - головная боль; часто - сонливость, синдром запястного канала (в основном наблюдался у пациенток с факторами риска развития данного заболевания), нарушение чувствительности (в том числе парестезия, потеря или извращение вкусовых ощущений).\u003Cbr\u003EСо стороны обмена веществ и питания: часто - анорексия, гиперхолестеринемия; нечасто - гиперкальциемия (с/без повышения концентрации паратгормона).\u003Cbr\u003EПрием анастрозола может вызывать снижение минеральной плотности костной ткани в связи со снижением концентрации циркулирующего эстрадиола, тем самым, повышая риск возникновения остеопороза и переломов костей.\u003Cbr\u003EОбщие расстройства: очень часто астения легкой или умеренной степени тяжести. Нежелательные явления, отмеченные в ходе клинических исследований, не связанные с приемом анастрозола: анемия, запор, диспепсия, боль в спине, абдоминальная боль, повышение артериального давления, повышение массы тела, депрессия, бессонница, головокружение, тревожность, парестезии."},{"name":"Фармакологическое действие","value":"Анастрозол является высокоселективным нестероидным ингибитором ароматазы - фермента, с помощью которого у женщин в постменопаузе андростендион в периферических тканях превращается в эстрон и далее в эстрадиол. Снижение концентрации циркулирующего эстрадиола у пациентов с раком молочной железы оказывает терапевтический эффект. У женщин в постменопаузе анастрозол в суточной дозе 1 мг вызывает снижение концентрации эстрадиола на 80%.\u003Cbr\u003EАнастрозол не обладает прогестогенной, андрогенной и эстрогенной активностью. В суточных дозах до 10 мг не оказывает эффекта на секрецию кортизола и альдостерона, следовательно, при применении анастрозола не требуется заместительного введения кортикостероидов."},{"name":"Фармакологическая группа","value":"противоопухолевые средства","transition":{"type":"catalog","params":{"categorySlug":"protivoopukholevye-preparaty-i-immunomoduliatory","categoryId":"15756914","navnodeId":"72508","glfilters":["34045110:34518988"]}}},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"protivoopukholevye-preparaty-i-immunomoduliatory","categoryId":"15756914","navnodeId":"72508","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"Список Б. При температуре не выше 25 °С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Описаны единичные клинические случаи случайной передозировки препарата. Разовая доза анастрозола, которая могла бы привести к симптомам, угрожающим жизни, не установлена.\u003Cbr\u003EСпецифического антидота не существует, в случае передозировки лечение должно быть симптоматическим. Можно индуцировать рвоту, если пациент находится в сознании. Может быть проведен диализ. Рекомендуется общая поддерживающая терапия, наблюдение за пациентом и контроль функций жизненно важных органов и систем."},{"name":"Применение при беременности и кормлении грудью","value":"Противопоказано."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Некоторые побочные действия анастрозола, такие как астения и сонливость, могут отрицательно влиять на способность выполнения потенциально опасных видов деятельности, требующих повышенной концентрации внимания и быстроты психомоторных реакций. В этой связи рекомендуется при появлении этих симптомов соблюдать осторожность при управлении транспортными средствами и механизмами."},{"name":"Особые указания","value":"В случае сомнений в гормональном статусе пациентки, менопауза должна быть подтверждена определением концентрации половых гормонов в сыворотке крови.\u003Cbr\u003EВ случае сохраняющегося маточного кровотечения на фоне приема анастрозола необходима консультация и наблюдение гинеколога.\u003Cbr\u003EНет данных о применении анастрозола у пациенток с тяжелой степенью нарушений функции печени.\u003Cbr\u003EУ пациенток с остеопорозом или с повышенным риском развития остеопороза, минеральную плотность костной ткани следует оценивать методом денситометрии, например, DEXA-сканированием (двухэнергетическая рентгеновская абсорбциометрия), в начале лечения и регулярно на его протяжении. При необходимости следует назначать лечение или профилактику остеопороза и тщательно наблюдать за состоянием пациентки. Поскольку анастрозол снижает концентрацию циркулирующего эстрадиола, это может привести к снижению минеральной плотности костной ткани. На настоящий момент отсутствуют достаточные данные относительно положительного влияния бисфосфонатов на потерю минеральной плотности костной ткани, вызванной анастрозолом или их пользы при применении с целью профилактики.\u003Cbr\u003EНет данных об одновременном применении анастрозола и препаратов-аналогов гонадотропин - рилизинг гормона.\u003Cbr\u003EУ женщин с рецептороотрицательной опухолью к эстрогенам эффективность анастрозола не была продемонстрирована, кроме тех случаев, когда имелся предшествующий положительный клинический ответ на тамоксифен.\u003Cbr\u003EПрепараты, содержащие эстрогены, не должны назначаться одновременно с анастрозолом, так как эти препараты будут нивелировать его фармакологическое действие. Эффективность и безопасность анастрозола и тамоксифена при их одновременном применении вне зависимости от статуса гормональных рецепторов сравнимы с таковыми при использовании одного тамоксифена. Точный механизм данного явления пока не известен.\u003Cbr\u003EНеизвестно улучшает ли анастрозол результаты лечения при совместном использовании с химиотерапией."},{"name":"Взаимодействие","value":"Исследования по лекарственному взаимодействию с феназоном (Антипирином) и циметидином указывают на то, что совместное применение анастрозола с другими препаратами вряд ли приведет к клинически значимому лекарственному взаимодействию, опосредованному цитохромом Р450.\u003Cbr\u003EКлинически значимое лекарственное взаимодействие при приёме анастрозола одновременно с другими часто назначаемыми препаратами отсутствует.\u003Cbr\u003EНа данный момент нет сведений о применении анастрозола в комбинации с другими противоопухолевыми препаратами.\u003Cbr\u003EПрепараты, содержащие эстрогены, уменьшают фармакологическое действие анастрозола, в связи с чем они не должны назначаться одновременно с анастрозолом.\u003Cbr\u003EНе следует назначать тамоксифен одновременно с анастрозолом поскольку он может ослабить фармакологическое действие последнего."},{"name":"Регистрационный номер","value":"ЛСР-001175/10"},{"name":"Дата государственной регистрации","value":"21.02.2019"},{"name":"Владелец регистрационного удостоверения","value":"TEVA","transition":{"type":"catalog","params":{"categorySlug":"protivoopukholevye-preparaty-i-immunomoduliatory","categoryId":"15756914","navnodeId":"72508","glfilters":["34324371:35649313","7893318:14909142"]}}},{"name":"Изготовитель","value":"Teva"},{"name":"Фасовщик","value":"Teva"},{"name":"Страна бренда","value":"Израиль"},{"name":"Страна-производитель","value":"Израиль"},{"name":"Название препарата","value":"Анастрозол-Тева","transition":{"type":"catalog","params":{"categorySlug":"protivoopukholevye-preparaty-i-immunomoduliatory","categoryId":"15756914","navnodeId":"72508","glfilters":["17796364:18053072"]}}},{"name":"Срок годности","value":"36 мес."}]}},"fullSpecsGrouped":{"8140570058911000427":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"молочные железы"},{"name":"Назначение","value":"рак молочной железы"},{"name":"Показания к применению","value":"- Адъювантная терапия раннего рака молочной железы с положительными гормональными рецепторами у женщин в постменопаузе, в том числе, после адъювантной терапии тамоксифеном в течение 2-3 лет.\u003Cbr\u003E- Первая линия терапии местно-распространенного или метастатического рака молочной железы, с положительными или неизвестными гормональными рецепторами у женщин в постменопаузе.\u003Cbr\u003E- Вторая линия терапии распространенного рака молочной железы, прогрессирующего после лечения тамоксифеном у женщин в постменопаузе."},{"name":"Противопоказания","value":"- Повышенная чувствительность к анастрозолу или другим компонентам препарата.\u003Cbr\u003E- Пременопаузальный период.\u003Cbr\u003E- Выраженная печеночная недостаточность (безопасность и эффективность не установлена).\u003Cbr\u003E- Сопутствующая терапия тамоксифеном или препаратами, содержащими эстрогены.\u003Cbr\u003E- Беременность и период кормления грудью.\u003Cbr\u003E- Детский возраст (безопасность и эффективность у детей не установлена).\u003Cbr\u003E- Недостаточность лактазы, непереносимость лактозы, глюкозо-галактозная мальабсорбция."},{"name":"Состав","value":"Активное вещество анастрозол 1,0 мг;\u003Cbr\u003EВспомогательные вещества: лактозы моногидрат (200 меш) 64,0 мг, повидон-К30 4,0 мг, лактозы моногидрат (высушенный распылением) 23,0 мг, карбоксиметилкрахмал натрия, тип А 7,0 мг, магния стеарат 1,0 мг, опадрай белый 02G28619 (гипромеллоза Е464 1,8750 мг, титана диоксид Е171 0,6375мг, макрогол-6000 0,3000 мг, макрогол-400 0,1875 мг)."},{"name":"Действующее вещество","value":"Анастрозол"},{"name":"Способ применения и дозы","value":"Внутрь. Таблетку проглатывают целиком, запивая водой. Рекомендуется принимать препарат в одно и то же время вне зависимости от приема пищи.\u003Cbr\u003EВзрослые, включая пожилых: по 1 мг внутрь 1 раз в сутки длительно. При появлении признаков прогрессирования заболевания прием препарата следует прекратить. В качестве адъювантной терапии рекомендуемая продолжительность лечения - 5 лет.\u003Cbr\u003EНарушения функции почек: коррекция дозы у пациентов с нарушением функции почек не требуется.\u003Cbr\u003EНарушения функции печени: коррекция дозы у пациентов с легкой и умеренной степенью нарушения функции печени не требуется."},{"name":"Побочные действия","value":"Частота побочных реакций, приведенных ниже, определялась соответственно следующим критериям: очень часто (не менее 1/10); часто (более 1/100, менее 1/10), нечасто (более 1/1000, менее 1/100), редко - (более 1/10000, менее 1/1000); очень редко (менее 1/10000), включая отдельные сообщения.\u003Cbr\u003EСо стороны сосудов: очень часто - “приливы” крови к лицу.\u003Cbr\u003EСо стороны скелетно-мышечной и соединительной ткани: очень часто артралгия/скованность суставов, артрит; часто - боль в костях, миалгия; нечасто - триггерный палец.\u003Cbr\u003EСо стороны половых органов и молочной железы: часто - сухость слизистой оболочки влагалища, влагалищное кровотечение (в основном в течение первых недель после отмены или смены предшествующей гормональной терапии на анастрозол).\u003Cbr\u003EСо стороны кожи и подкожных тканей: очень часто - кожная сыпь; часто - истончение волос, алопеция, аллергические реакции; нечасто - крапивница; редко - мультиформная эритема, анафилактоидная реакция, кожный васкулит (включая отдельные случаи пурпуры (синдром Шенлейна-Геноха)); очень редко - синдром Стивенса-Джонсона, ангионевротический отек.\u003Cbr\u003EСо стороны желудочно-кишечного тракта: очень часто - тошнота; часто - диарея, рвота.\u003Cbr\u003EСо стороны печени и желчевыводящих путей: часто - повышение активности щелочной фосфатазы, аланинаминотрансферазы, аспартатаминотрансферазы; нечасто - повышение активности гамма-глутамил-трансферазы и концентрации билирубина, гепатит.\u003Cbr\u003EСо стороны нервной системы: очень часто - головная боль; часто - сонливость, синдром запястного канала (в основном наблюдался у пациенток с факторами риска развития данного заболевания), нарушение чувствительности (в том числе парестезия, потеря или извращение вкусовых ощущений).\u003Cbr\u003EСо стороны обмена веществ и питания: часто - анорексия, гиперхолестеринемия; нечасто - гиперкальциемия (с/без повышения концентрации паратгормона).\u003Cbr\u003EПрием анастрозола может вызывать снижение минеральной плотности костной ткани в связи со снижением концентрации циркулирующего эстрадиола, тем самым, повышая риск возникновения остеопороза и переломов костей.\u003Cbr\u003EОбщие расстройства: очень часто астения легкой или умеренной степени тяжести. Нежелательные явления, отмеченные в ходе клинических исследований, не связанные с приемом анастрозола: анемия, запор, диспепсия, боль в спине, абдоминальная боль, повышение артериального давления, повышение массы тела, депрессия, бессонница, головокружение, тревожность, парестезии."},{"name":"Фармакологическое действие","value":"Анастрозол является высокоселективным нестероидным ингибитором ароматазы - фермента, с помощью которого у женщин в постменопаузе андростендион в периферических тканях превращается в эстрон и далее в эстрадиол. Снижение концентрации циркулирующего эстрадиола у пациентов с раком молочной железы оказывает терапевтический эффект. У женщин в постменопаузе анастрозол в суточной дозе 1 мг вызывает снижение концентрации эстрадиола на 80%.\u003Cbr\u003EАнастрозол не обладает прогестогенной, андрогенной и эстрогенной активностью. В суточных дозах до 10 мг не оказывает эффекта на секрецию кортизола и альдостерона, следовательно, при применении анастрозола не требуется заместительного введения кортикостероидов."},{"name":"Фармакологическая группа","value":"противоопухолевые средства"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"Список Б. При температуре не выше 25 °С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Описаны единичные клинические случаи случайной передозировки препарата. Разовая доза анастрозола, которая могла бы привести к симптомам, угрожающим жизни, не установлена.\u003Cbr\u003EСпецифического антидота не существует, в случае передозировки лечение должно быть симптоматическим. Можно индуцировать рвоту, если пациент находится в сознании. Может быть проведен диализ. Рекомендуется общая поддерживающая терапия, наблюдение за пациентом и контроль функций жизненно важных органов и систем."},{"name":"Применение при беременности и кормлении грудью","value":"Противопоказано."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Некоторые побочные действия анастрозола, такие как астения и сонливость, могут отрицательно влиять на способность выполнения потенциально опасных видов деятельности, требующих повышенной концентрации внимания и быстроты психомоторных реакций. В этой связи рекомендуется при появлении этих симптомов соблюдать осторожность при управлении транспортными средствами и механизмами."},{"name":"Особые указания","value":"В случае сомнений в гормональном статусе пациентки, менопауза должна быть подтверждена определением концентрации половых гормонов в сыворотке крови.\u003Cbr\u003EВ случае сохраняющегося маточного кровотечения на фоне приема анастрозола необходима консультация и наблюдение гинеколога.\u003Cbr\u003EНет данных о применении анастрозола у пациенток с тяжелой степенью нарушений функции печени.\u003Cbr\u003EУ пациенток с остеопорозом или с повышенным риском развития остеопороза, минеральную плотность костной ткани следует оценивать методом денситометрии, например, DEXA-сканированием (двухэнергетическая рентгеновская абсорбциометрия), в начале лечения и регулярно на его протяжении. При необходимости следует назначать лечение или профилактику остеопороза и тщательно наблюдать за состоянием пациентки. Поскольку анастрозол снижает концентрацию циркулирующего эстрадиола, это может привести к снижению минеральной плотности костной ткани. На настоящий момент отсутствуют достаточные данные относительно положительного влияния бисфосфонатов на потерю минеральной плотности костной ткани, вызванной анастрозолом или их пользы при применении с целью профилактики.\u003Cbr\u003EНет данных об одновременном применении анастрозола и препаратов-аналогов гонадотропин - рилизинг гормона.\u003Cbr\u003EУ женщин с рецептороотрицательной опухолью к эстрогенам эффективность анастрозола не была продемонстрирована, кроме тех случаев, когда имелся предшествующий положительный клинический ответ на тамоксифен.\u003Cbr\u003EПрепараты, содержащие эстрогены, не должны назначаться одновременно с анастрозолом, так как эти препараты будут нивелировать его фармакологическое действие. Эффективность и безопасность анастрозола и тамоксифена при их одновременном применении вне зависимости от статуса гормональных рецепторов сравнимы с таковыми при использовании одного тамоксифена. Точный механизм данного явления пока не известен.\u003Cbr\u003EНеизвестно улучшает ли анастрозол результаты лечения при совместном использовании с химиотерапией."},{"name":"Взаимодействие","value":"Исследования по лекарственному взаимодействию с феназоном (Антипирином) и циметидином указывают на то, что совместное применение анастрозола с другими препаратами вряд ли приведет к клинически значимому лекарственному взаимодействию, опосредованному цитохромом Р450.\u003Cbr\u003EКлинически значимое лекарственное взаимодействие при приёме анастрозола одновременно с другими часто назначаемыми препаратами отсутствует.\u003Cbr\u003EНа данный момент нет сведений о применении анастрозола в комбинации с другими противоопухолевыми препаратами.\u003Cbr\u003EПрепараты, содержащие эстрогены, уменьшают фармакологическое действие анастрозола, в связи с чем они не должны назначаться одновременно с анастрозолом.\u003Cbr\u003EНе следует назначать тамоксифен одновременно с анастрозолом поскольку он может ослабить фармакологическое действие последнего."},{"name":"Регистрационный номер","value":"ЛСР-001175/10"},{"name":"Дата государственной регистрации","value":"21.02.2019"},{"name":"Владелец регистрационного удостоверения","value":"TEVA"},{"name":"Изготовитель","value":"Teva"},{"name":"Фасовщик","value":"Teva"},{"name":"Страна бренда","value":"Израиль"},{"name":"Страна-производитель","value":"Израиль"},{"name":"Название препарата","value":"Анастрозол-Тева"},{"name":"Срок годности","value":"36 мес."}]}],"transitionId":"tr_6"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

Где купить

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В качестве адъювантной терапии рекомендуемая продолжительность лечения - 5 лет.\u003Cbr\u003EНарушения функции почек: коррекция дозы у пациентов с нарушением функции почек не требуется.\u003Cbr\u003EНарушения функции печени: коррекция дозы у пациентов с легкой и умеренной степенью нарушения функции печени не требуется."},{"description":"","filters":[{"id":15767998,"name":"Побочные действия"}],"isMainProperty":false,"name":"Побочные действия","value":"Частота побочных реакций, приведенных ниже, определялась соответственно следующим критериям: очень часто (не менее 1/10); часто (более 1/100, менее 1/10), нечасто (более 1/1000, менее 1/100), редко - (более 1/10000, менее 1/1000); очень редко (менее 1/10000), включая отдельные сообщения.\u003Cbr\u003EСо стороны сосудов: очень часто - “приливы” крови к лицу.\u003Cbr\u003EСо стороны скелетно-мышечной и соединительной ткани: очень часто артралгия/скованность суставов, артрит; часто - боль в костях, миалгия; нечасто - триггерный палец.\u003Cbr\u003EСо стороны половых органов и молочной железы: часто - сухость слизистой оболочки влагалища, влагалищное кровотечение (в основном в течение первых недель после отмены или смены предшествующей гормональной терапии на анастрозол).\u003Cbr\u003EСо стороны кожи и подкожных тканей: очень часто - кожная сыпь; часто - истончение волос, алопеция, аллергические реакции; нечасто - крапивница; редко - мультиформная эритема, анафилактоидная реакция, кожный васкулит (включая отдельные случаи пурпуры (синдром Шенлейна-Геноха)); очень редко - синдром Стивенса-Джонсона, ангионевротический отек.\u003Cbr\u003EСо стороны желудочно-кишечного тракта: очень часто - тошнота; часто - диарея, рвота.\u003Cbr\u003EСо стороны печени и желчевыводящих путей: часто - повышение активности щелочной фосфатазы, аланинаминотрансферазы, аспартатаминотрансферазы; нечасто - повышение активности гамма-глутамил-трансферазы и концентрации билирубина, гепатит.\u003Cbr\u003EСо стороны нервной системы: очень часто - головная боль; часто - сонливость, синдром запястного канала (в основном наблюдался у пациенток с факторами риска развития данного заболевания), нарушение чувствительности (в том числе парестезия, потеря или извращение вкусовых ощущений).\u003Cbr\u003EСо стороны обмена веществ и питания: часто - анорексия, гиперхолестеринемия; нечасто - гиперкальциемия (с/без повышения концентрации паратгормона).\u003Cbr\u003EПрием анастрозола может вызывать снижение минеральной плотности костной ткани в связи со снижением концентрации циркулирующего эстрадиола, тем самым, повышая риск возникновения остеопороза и переломов костей.\u003Cbr\u003EОбщие расстройства: очень часто астения легкой или умеренной степени тяжести. Нежелательные явления, отмеченные в ходе клинических исследований, не связанные с приемом анастрозола: анемия, запор, диспепсия, боль в спине, абдоминальная боль, повышение артериального давления, повышение массы тела, депрессия, бессонница, головокружение, тревожность, парестезии."},{"description":"","filters":[{"id":15768001,"name":"Фармакологическое действие"}],"isMainProperty":false,"name":"Фармакологическое действие","value":"Анастрозол является высокоселективным нестероидным ингибитором ароматазы - фермента, с помощью которого у женщин в постменопаузе андростендион в периферических тканях превращается в эстрон и далее в эстрадиол. Снижение концентрации циркулирующего эстрадиола у пациентов с раком молочной железы оказывает терапевтический эффект. У женщин в постменопаузе анастрозол в суточной дозе 1 мг вызывает снижение концентрации эстрадиола на 80%.\u003Cbr\u003EАнастрозол не обладает прогестогенной, андрогенной и эстрогенной активностью. В суточных дозах до 10 мг не оказывает эффекта на секрецию кортизола и альдостерона, следовательно, при применении анастрозола не требуется заместительного введения кортикостероидов."},{"description":"","filters":[{"id":34045110,"name":"Фармакологическая группа"}],"isMainProperty":false,"name":"Фармакологическая группа","value":"противоопухолевые средства"},{"description":"","filters":[{"id":27141511,"name":"Форма выпуска для карточки"}],"isMainProperty":false,"name":"Форма выпуска","value":"таблетки"},{"description":"","filters":[{"id":35947170,"name":"Способ применения/введения"}],"isMainProperty":false,"name":"Способ применения/введения","value":"пероральный"},{"description":"","filters":[{"id":23679511,"name":"Минимальный возраст применения"},{"id":16082123,"name":"С рождения"}],"isMainProperty":false,"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","specs":[{"description":"","filters":[{"id":15767999,"name":"Условия хранения"}],"isMainProperty":false,"name":"Условия хранения","value":"Список Б. При температуре не выше 25 °С. Хранить в недоступном для детей месте."},{"description":"","filters":[{"id":15768014,"name":"Передозировка"}],"isMainProperty":false,"name":"Передозировка","value":"Описаны единичные клинические случаи случайной передозировки препарата. Разовая доза анастрозола, которая могла бы привести к симптомам, угрожающим жизни, не установлена.\u003Cbr\u003EСпецифического антидота не существует, в случае передозировки лечение должно быть симптоматическим. Можно индуцировать рвоту, если пациент находится в сознании. Может быть проведен диализ. Рекомендуется общая поддерживающая терапия, наблюдение за пациентом и контроль функций жизненно важных органов и систем."},{"description":"","filters":[{"id":15768015,"name":"Применение при беременности и кормлении грудью"}],"isMainProperty":false,"name":"Применение при беременности и кормлении грудью","value":"Противопоказано."},{"description":"","filters":[{"id":17360993,"name":"Влияние на способность управлять транспортом и механизмами"}],"isMainProperty":false,"name":"Влияние на способность управлять транспортом и механизмами","value":"Некоторые побочные действия анастрозола, такие как астения и сонливость, могут отрицательно влиять на способность выполнения потенциально опасных видов деятельности, требующих повышенной концентрации внимания и быстроты психомоторных реакций. В этой связи рекомендуется при появлении этих симптомов соблюдать осторожность при управлении транспортными средствами и механизмами."},{"description":"","filters":[{"id":15771167,"name":"Особые указания"}],"isMainProperty":false,"name":"Особые указания","value":"В случае сомнений в гормональном статусе пациентки, менопауза должна быть подтверждена определением концентрации половых гормонов в сыворотке крови.\u003Cbr\u003EВ случае сохраняющегося маточного кровотечения на фоне приема анастрозола необходима консультация и наблюдение гинеколога.\u003Cbr\u003EНет данных о применении анастрозола у пациенток с тяжелой степенью нарушений функции печени.\u003Cbr\u003EУ пациенток с остеопорозом или с повышенным риском развития остеопороза, минеральную плотность костной ткани следует оценивать методом денситометрии, например, DEXA-сканированием (двухэнергетическая рентгеновская абсорбциометрия), в начале лечения и регулярно на его протяжении. При необходимости следует назначать лечение или профилактику остеопороза и тщательно наблюдать за состоянием пациентки. Поскольку анастрозол снижает концентрацию циркулирующего эстрадиола, это может привести к снижению минеральной плотности костной ткани. На настоящий момент отсутствуют достаточные данные относительно положительного влияния бисфосфонатов на потерю минеральной плотности костной ткани, вызванной анастрозолом или их пользы при применении с целью профилактики.\u003Cbr\u003EНет данных об одновременном применении анастрозола и препаратов-аналогов гонадотропин - рилизинг гормона.\u003Cbr\u003EУ женщин с рецептороотрицательной опухолью к эстрогенам эффективность анастрозола не была продемонстрирована, кроме тех случаев, когда имелся предшествующий положительный клинический ответ на тамоксифен.\u003Cbr\u003EПрепараты, содержащие эстрогены, не должны назначаться одновременно с анастрозолом, так как эти препараты будут нивелировать его фармакологическое действие. Эффективность и безопасность анастрозола и тамоксифена при их одновременном применении вне зависимости от статуса гормональных рецепторов сравнимы с таковыми при использовании одного тамоксифена. Точный механизм данного явления пока не известен.\u003Cbr\u003EНеизвестно улучшает ли анастрозол результаты лечения при совместном использовании с химиотерапией."},{"description":"","filters":[{"id":15768012,"name":"Взаимодействие"}],"isMainProperty":false,"name":"Взаимодействие","value":"Исследования по лекарственному взаимодействию с феназоном (Антипирином) и циметидином указывают на то, что совместное применение анастрозола с другими препаратами вряд ли приведет к клинически значимому лекарственному взаимодействию, опосредованному цитохромом Р450.\u003Cbr\u003EКлинически значимое лекарственное взаимодействие при приёме анастрозола одновременно с другими часто назначаемыми препаратами отсутствует.\u003Cbr\u003EНа данный момент нет сведений о применении анастрозола в комбинации с другими противоопухолевыми препаратами.\u003Cbr\u003EПрепараты, содержащие эстрогены, уменьшают фармакологическое действие анастрозола, в связи с чем они не должны назначаться одновременно с анастрозолом.\u003Cbr\u003EНе следует назначать тамоксифен одновременно с анастрозолом поскольку он может ослабить фармакологическое действие последнего."},{"description":"","filters":[{"id":16435314,"name":"Регистрационный номер"}],"isMainProperty":false,"name":"Регистрационный номер","value":"ЛСР-001175/10"},{"description":"","filters":[{"id":16435315,"name":"Дата государственной регистрации"}],"isMainProperty":false,"name":"Дата государственной регистрации","value":"21.02.2019"},{"description":"","filters":[{"id":34324371,"name":"Тип препарата"},{"id":7893318,"name":"Производитель"}],"isMainProperty":false,"name":"Владелец регистрационного удостоверения","value":"TEVA"},{"description":"","filters":[{"id":35771390,"name":"Изготовитель"}],"isMainProperty":false,"name":"Изготовитель","value":"Teva"},{"description":"","filters":[{"id":34543370,"name":"Фасовщик"}],"isMainProperty":false,"name":"Фасовщик","value":"Teva"},{"description":"","filters":[{"id":32849454,"name":"Страна 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    Цена 1 153 ₽ вместо 1 459
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  • Аримидекс таб. п/о плен., 1 мг, 28 шт.
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    Аримидекс таб. п/о плен., 1 мг, 28 шт.

    Рейтинг товара: 5 из 5
    на основе 3 оценки
    Цена 1 458 ₽
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  • Аназалес таб., 1 мг, 28 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-rw07crc8d7/toggleWishlist":{"skuId":"101335818799","productId":662061002,"offerId":"LEqOW8vlD8HeTTL27QiSwg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgsQ+Z+J8YzV696GARIxCi9Db21wZXRpdGl2ZUFuYWxvZ3NfTWFya2V0TW9kZWxDYXJkX0Zyb250U25pcHBldDIXCMr/2LsCEK/E18D5AhiJgLoIIPLcwQc=","sign":"xr0pP3pD4A8jgX0OA01LPQJ+ueKUNJrUndepsTyvsQE="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-rw07crc8d7/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Аназалес таб., 1 мг, 28 шт.

    Рейтинг товара: 5 из 5
    на основе 2 оценки
    Цена 1 154 ₽
    {"widgets":{"@light/AddToCartButtonSnippet":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-rw07crc8d7/addToCartButton":{"offerId":"LEqOW8vlD8HeTTL27QiSwg","skuId":"101335818799","pendingCartItem":{"productId":662061002,"offerId":"LEqOW8vlD8HeTTL27QiSwg","showPlaceId":"OTNDnItfwRMjN9MRHuEMMiBZlMWn9tgIkGtuNaE64rbxI-96RYe3MHg-PhSZVKWJ3cSdfyH4xIzSVHnstJRdfVhZZB3cTQSL87kFbFBrdbQAX_4LXcNTw5Gc9fB1CV7Pbws5BMBLq3nMkSScZTJ7M63OEMAoAg8ME-uxCgnU4p6a0KlPQrGbo1lWNHTKlVIiIXZw2p2wczJWUDIpaxOt6g,,","feeShow":"OTNDnItfwRMjN9MRHuEMMiBZlMWn9tgIkGtuNaE64rbxI-96RYe3MHg-PhSZVKWJ3cSdfyH4xIzSVHnstJRdfVhZZB3cTQSL87kFbFBrdbQAX_4LXcNTw5Gc9fB1CV7Pbws5BMBLq3nMkSScZTJ7M63OEMAoAg8ME-uxCgnU4p6a0KlPQrGbo1lWNHTKlVIiIXZw2p2wczJWUDIpaxOt6g,,","skuId":"101335818799","shopId":55106433,"price":{"applicablePriceDiscounts":[],"value":"1154","currency":"RUR"},"hid":"15756914","name":"Аназалес таб., 1 мг, 28 шт.","label":"3gmrnum5q02","count":0,"features":[],"imageMeta":{"namespace":"mpic","groupId":4334326,"key":"img_id2997492316023858325.jpeg"}},"quantity":{"step":1,"minimum":1,"maximum":999},"cpaUrl":"/safeclick/data=TxNGOK9vJEN7oLFLeCTKEixJYuEMI0EzvZFs82AjjgjhTwweZ7mRXd_AQ0K184sfZmy5nQz7U8xIc-qdVOMFoxnoSww2ObzLEs1KJpltGipDSanCui6QCo8GXRHxAQaqQQZbzp5kb0bdQDXqQiIIDEwL4INEBUjrbUNtjxqZ96WFVmZtSFtMyd00zHc5eP2a4OrrJritdvhIopl_2vbDZ7BeLVM2WDO1I9m3DRn6ep0QQPPf9kF36b2uqq53jfWCJeHIQKIkjEkuzdjM3BkmRlWqPZJRlEXCR63UA7_G5gYjIcpmlioxNSP-0GQlnoVD0p-C5PvNUNBKdw3drpGfOsr_0pkuPOZYbk8Y4VrIzBe1MTZD1c8lFFz2H54z5MkBjRQOxno7gB8M_hZbjm4XUBMhdXxmx6nrINk1onVDhwUAZz59WOOx5Kqc3IzLoDi1a5Fvp5_LSJxPFZKGw0ygVoRwSTtDmsXSe1H9Vr4Ie77KpmO8FMmdAclR80jKRQUHugzYCYaUrRS5nTw0ZQHLu8L-kKlXKOJhBYNNcL4CGqHaP-4-Ep9tOe0Ch6t9fxVioy-0q9lGUu9apz3M8dizRkceP7--5VYaTDzDUrjd__7Ql-pr__Jfu3Ff0qIVpEuJpoaKcE7LAt8CM0aUKjSOzuubLfsHMbBYVyvxJjGHzKcc3xImH1S0eLtOG0ylA-egwhvW3D83IvvbAjtw27g3lfISIHB3hiuj35irZmh4LgcP3X5JyPic6x7Zg6p-ECos9SL3uzcgWl_LnOp_NTEJohBj4-ms0RQmbWhl6-2XdmZNK9Utplo0ViBSqRO6i6zk9wPan0WUBBmCny5450zpeSMk4e8Aaj2R_vRjQsehi9k5UyOUAvF-Vx1fFMpx-m2VqzgLuqeQRU6DrafXjOftOgyUNMgXygApYbeu761O_K8UdymSP8DkEdjZ5t7nOuKbqYcnTgHtXDLbWJvukhUZ2z7MLkbJ6GNUIfORm0u8mYnd6ovAJ-Jaz5XK2PP9U1t75VGZfcBa1Uz3l6Km5Q5DpQb7_lMPhxV7gUujJMxenpKGz0ULCzRZThgbSJIXVE7Lu9HiKYi6iVJ58bSoqe9d9jpk-ftxP-7_39TgtE8UxA-nfwdCrR3cy4DKX4znBlfSBqUMTjnLJkoGdgG0cGNRl9WedbT3czqxlOXqYHKNXd0eUgrE9UGgJjpOhKp4j1ZjpuJEJ98YqG2YZ4XlEE1_7k_oiu9VFBsQrg4HPoAksrfY3psUUDzzco0iuY8GiniqosTP07XnithqliHmT3b5-OCD19SPI1YudrmfWxDkSImpJRHMRxBaTQaqT6fpsvlvQ7MtBj2Qg63pblv0iP-4TnPapCg021cOW-OVUe1LgL0C3wTsRQfVkW95te3cgofgfJ6_MSMjKbfdiKLHjoloMV8AhLYW2-DyE9T4FP1bBpEULzXTMZjYHxTuW8F95HrC67dSadiJOBT-i5GpeKgDrIRaqIRr1L0KColulGgKZr1rFR1vHaDoACHsJd-AVRWvtxgFOzDX5Y85k_3dqRpI6fyRSb3RUqhyBAAJntXHNJ60NplJJyKD_adjMIhjyyEd66Jemz7n6Skv3Q-O8yhd3ORsJ1N5mRgskvMUUVBy2BWuus-U-Wl8y_WVT8tohRC5FtJtBLw0I0sqNtl0X-KOXM8wTOA29wGIR_MiYa5unXsIEuXZtR64n_B5FlzaHi9Bsx69uDXDW3vlaFLhdvknkY2j7B6wyDMglzBzhAfU4l6G7PlmlKTcLHxOFDoIumkCKTtUhCGULTIfvN9l3FjKobGw4eYQnhS8bDFIoffRA2rtnVT2VmhiZIXNqccyCnlgf2mbo2bhffu37I1oQ1kSEPRjDJm_eM_Ekv60OzCYwRi1VuSV_fJhW3Fj5Li3zOkOOwWrnUaattcsggnTsQAT8FwbO9HPwbYJcCfCGpvazraxZaTp0_VuhE66mnYki4CCIvDkvdTTaDhY7lKozDKPBXxui-D4BgyOxvjf1WMWn6UzCv_leF-mNX96NR_P7PXV7BNHsmpg_OAWNGaCCloZqxdQw3i2TYAO4G8n5a6qDvXDGv1fO0Y_i4jSVOUUBDY4KbE24vPGDpDojWBsDCd0fXQT3cQTOF1eMxFPZfjLT3A0G5jXVJRXv4SjRiFzERFjdukNP85x1uGaDZFr-XjN7K2IHDyUps1dZdV5wbqVSyIDRz7_jsjjXs0eHf34Pmoybd6wcJi6e7_eSYOANIM-FxQh-pnXOzmWwNX_5ZUvcny8IUdqreQ-AZV3dI79oMGeX0ZUXsObRCbh7KQHeYZqId7HfLNhMPp81MPJn6oVhrPeWEnah9Ik-aCrzbPApWCaQ3tntn6IppzpmiBSwYDm-CcLeA5-Rkhs7ycHLKGnjpNmO4ZlhS_JshAgfvSsikX-EFsxt5Vf9aNbYn6Rse4El7ZBzMEjHLe9twlaCnX87NrE0yk1bcSHBQEWtyGcrik4XJ_DIVql09aJZ9UKiQ4QJPI8Y8cQFu-ax4St9rfIMIFHvM9hiC2EftZPmuKziRLbBLNNVWBFORq1u-O25lPaMX-mr62EPudIaCWhtB4gntSrSQuxoOS76d611MIvnQkB5wSyOXdWPJg1e2xn_6csQKc9uQM9jWNmjHTYEc9k-N9OPtLjVTjukogMYXO3QD0MoFvWDkSzN8U_bjXTLhtHQOnpwBoBFJ6UYuTfNy64zQ8oBKsXKRhBOr_UaLPMdR1Cnaj4ol2FgqWbaZhe2JlZthv6Mfc_I8VLtYZG6Irpftjs5-1tAYIXxFndHso3-kJ-ghfNGx-Z7MekCvlMk-BTwGub8hIQNPJUM-t5k8iLd5Z5FakLBL_1x9CxIy0lIJs_XpzOQuLISAHdkE0dyWw6m0USdnUN3g8qUmfCIMnBsQOMjnW829eg7OtCWqrlw9LkMkMWLziWs78E6Of-Jel3S-MBFGpxv-ROCDxqF_tkyeNfj_XZaaRjf5C62eFEfTXQuZJ-JlHkj0Xd2hGVkH1KftYRxkf7lBBcA4JZoUgTNE5eQhHDUgoCAmkqTt9XodrvF0jsslZmkCDYgxFw_wHfZe9ibYdg-SBjX43axnqLShLeiB7P-vkQho7q4O9CRLKrzg2T47XXE3tgH--7J0plcRzjO9xVeYROnAg7RHcejiFEk4zalJofXXP2cf084y8qKOdbXxWVYb5C_jPinpDnWHvZPeI6jPtWbbVlUPEPqDbh-4FNOM36de2fjeXUSYPNoRn2QVQ7bULOsMTB7IkK9glmcJKI3Qs427j6FqqQt3kdk03u4LvUeOWpFUX4zMtqUI5f7kBi3eh-pFVhKLeJLUXZev0JT1w96K8XaweF7nDRcuIGJHJbC0MKwUdKlwbqGci6ccAeHh9qThbxWVWkbmNstFgCdhZQ6GIRQ_mb7yfuwtpPrrL1aPuPUapR1wBL4zCwkrdX73Z_GRouBM6CX3x0D2Imxn7KjzG2bf9dUL8,/b64e=1/sign=51d9f3f8a8c44b44963f17a16659b214/keyno=MARKET_1/*","showUid":"17167514847246374171606003","cartLink":"/my/cart","showNotificationWhenDeleteItem":true,"isLavka":false,"isError":false,"isEats":false,"isCR":false,"isM2bEdoOnlyEnable":false,"isEatsMarketIntegration":true,"isCartButtonNext":false,"isUpsalePopupCRExp":false,"baobabClientDataAdditionToCart":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgsQ+Z+J8YzV696GARIxCi9Db21wZXRpdGl2ZUFuYWxvZ3NfTWFya2V0TW9kZWxDYXJkX0Zyb250U25pcHBldDIXCMr/2LsCEK/E18D5AhiJgLoIIPLcwQc=","sign":"xr0pP3pD4A8jgX0OA01LPQJ+ueKUNJrUndepsTyvsQE="},"target":"cart_addition"},"baobabClientDataDeletionFromCart":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgsQ+Z+J8YzV696GARIxCi9Db21wZXRpdGl2ZUFuYWxvZ3NfTWFya2V0TW9kZWxDYXJkX0Zyb250U25pcHBldDIXCMr/2LsCEK/E18D5AhiJgLoIIPLcwQc=","sign":"xr0pP3pD4A8jgX0OA01LPQJ+ueKUNJrUndepsTyvsQE="},"target":"cart_deletion"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-rw07crc8d7/addToCartButton":{"name":"@light/AddToCartButtonSnippet"}}}
  • Тамоксифен таб., 10 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-k8tz3yqks4/toggleWishlist":{"skuId":"101335813747","productId":228088817,"offerId":"LwQorKzZd-BaNmUGBkO_eQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgsQ+Z+J8YzV696GARIxCi9Db21wZXRpdGl2ZUFuYWxvZ3NfTWFya2V0TW9kZWxDYXJkX0Zyb250U25pcHBldDIWCPG34WwQ85zXwPkCGNfxzwYg8tzBBw==","sign":"hvfAfyABh+5oiw7L+upbFQx46T1n5+/Kv+9aOB2W3p8="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-k8tz3yqks4/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Тамоксифен таб., 10 мг, 30 шт.

    Рейтинг товара: 4.9 из 5
    на основе 38 оценок
    Цена 122 ₽
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  • Копаксон 40 р-р для п/к введ. шприц, 40 мг/мл, 1 мл, 12 шт.
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    Копаксон 40 р-р для п/к введ. шприц, 40 мг/мл, 1 мл, 12 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 24 645 ₽
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  • Бикалутамид-тева таб. п/о плен., 150 мг, 28 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ingm5h6h7wj/toggleWishlist":{"skuId":"101333036751","productId":227830073,"offerId":"5pHxJVplY0T9DfEkfB0gRA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgsQ+Z+J8YzV696GARIxCi9Db21wZXRpdGl2ZUFuYWxvZ3NfTWFya2V0TW9kZWxDYXJkX0Zyb250U25pcHBldDIWCLnS0WwQz92tv/kCGNb9jQcg8tzBBw==","sign":"dr1xAqOOoZ9m6JM+PiB6g9UYtCH1OzMII/8B4ZKNxn8="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ingm5h6h7wj/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Бикалутамид-тева таб. п/о плен., 150 мг, 28 шт.

    Рейтинг товара: 4.5 из 5
    на основе 23 оценки
    Цена 2 411 ₽
    {"widgets":{"@light/AddToCartButtonSnippet":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ingm5h6h7wj/addToCartButton":{"offerId":"5pHxJVplY0T9DfEkfB0gRA","skuId":"101333036751","pendingCartItem":{"productId":227830073,"offerId":"5pHxJVplY0T9DfEkfB0gRA","showPlaceId":"OTNDnItfwRMjN9MRHuEMMiBZlMWn9tgIcutkuYJK4e4EW44_WgbGyzXWXWyuFMwT0k9M39476aazSwICYLu-bUiBlCBbCaLUO2MOhhSH5k6LegIHOEuAhoR-g3Qfzh0AU75TGBMqEvsJ8AWwaXL1ldOvYB19jOb_T_yAV4I05yuETseN3uqtG6jjNHYc7hDO4V-65pGP6msmc-oz8M3gtQ,,","feeShow":"OTNDnItfwRMjN9MRHuEMMiBZlMWn9tgIcutkuYJK4e4EW44_WgbGyzXWXWyuFMwT0k9M39476aazSwICYLu-bUiBlCBbCaLUO2MOhhSH5k6LegIHOEuAhoR-g3Qfzh0AU75TGBMqEvsJ8AWwaXL1ldOvYB19jOb_T_yAV4I05yuETseN3uqtG6jjNHYc7hDO4V-65pGP6msmc-oz8M3gtQ,,","skuId":"101333036751","shopId":55106433,"price":{"applicablePriceDiscounts":[],"value":"2411","currency":"RUR"},"hid":"15756914","name":"Бикалутамид-тева таб. п/о плен., 150 мг, 28 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  • Лорета таб. п/о плен., 2.5 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-kkzxlqm0bx/toggleWishlist":{"skuId":"101335818766","productId":453475048,"offerId":"N-2jihGdbFak-E_UuIgtyA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgsQ+Z+J8YzV696GARIxCi9Db21wZXRpdGl2ZUFuYWxvZ3NfTWFya2V0TW9kZWxDYXJkX0Zyb250U25pcHBldDIXCOj1ndgBEI7E18D5AhjqvoYRIPLcwQc=","sign":"sxI7grU4HG68qGVeO+i4QYB0/QNXaCIl7hGdOS2XhnU="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-kkzxlqm0bx/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Лорета таб. п/о плен., 2.5 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 3 оценки
    Цена 1 449 ₽
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  • Лестродекс таб. п/о плен., 2.5 мг, 30 шт.
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    Лестродекс таб. п/о плен., 2.5 мг, 30 шт.

    Цена 1 959 ₽
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  • Фемара таб. п/о плен., 2.5 мг, 30 шт.
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    Фемара таб. п/о плен., 2.5 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 8 242 ₽
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Инструкция

Показания к применению

- Адъювантная терапия раннего рака молочной железы с положительными гормональными рецепторами у женщин в постменопаузе, в том числе, после адъювантной терапии тамоксифеном в течение 2-3 лет.
- Первая линия терапии местно-распространенного или метастатического рака молочной железы, с положительными или неизвестными гормональными рецепторами у женщин в постменопаузе.
- Вторая линия терапии распространенного рака молочной железы, прогрессирующего после лечения тамоксифеном у женщин в постменопаузе.

Противопоказания

- Повышенная чувствительность к анастрозолу или другим компонентам препарата.
- Пременопаузальный период.
- Выраженная печеночная недостаточность (безопасность и эффективность не установлена).
- Сопутствующая терапия тамоксифеном или препаратами, содержащими эстрогены.
- Беременность и период кормления грудью.
- Детский возраст (безопасность и эффективность у детей не установлена).
- Недостаточность лактазы, непереносимость лактозы, глюкозо-галактозная мальабсорбция.

Способ применения и дозы

Внутрь. Таблетку проглатывают целиком, запивая водой. Рекомендуется принимать препарат в одно и то же время вне зависимости от приема пищи.
Взрослые, включая пожилых: по 1 мг внутрь 1 раз в сутки длительно. При появлении признаков прогрессирования заболевания прием препарата следует прекратить. В качестве адъювантной терапии рекомендуемая продолжительность лечения - 5 лет.
Нарушения функции почек: коррекция дозы у пациентов с нарушением функции почек не требуется.
Нарушения функции печени: коррекция дозы у пациентов с легкой и умеренной степенью нарушения функции печени не требуется.
Полная инструкция
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Анастрозол-Тева таб. п/о плен.
Анастрозол-Тева таб. п/о плен., 1 мг, 28 шт.
5.0
(1)
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Рекомендуем

  • Таблетница из 14 секций на семь дней Утро-вечер
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    Таблетница из 14 секций на семь дней Утро-вечер

    Цена 167 ₽ вместо 200
  • Анастрозол таб. п/о плен., 1 мг, 30 шт.
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    Анастрозол таб. п/о плен., 1 мг, 30 шт.

    Цена 1 153 ₽ вместо 1 459
  • Аримидекс таб. п/о плен., 1 мг, 28 шт.
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    Аримидекс таб. п/о плен., 1 мг, 28 шт.

    Цена 1 458 ₽
  • Таблетница пенал - органайзер ABORNS на неделю 7 ячеек 7 дней
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    Таблетница пенал - органайзер ABORNS на неделю 7 ячеек 7 дней

    Цена 173 ₽ вместо 350
  • Таблетница пенал - органайзер ABORNS на неделю 7 ячеек 7 дней
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    Таблетница пенал - органайзер ABORNS на неделю 7 ячеек 7 дней

    Цена 226 ₽ вместо 400
  • Аназалес таб., 1 мг, 28 шт.
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    Аназалес таб., 1 мг, 28 шт.

    Цена 1 154 ₽
  • Тамоксифен таб., 10 мг, 30 шт.
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    Тамоксифен таб., 10 мг, 30 шт.

    Цена 122 ₽
  • Таблетница на 7 дней / органайзер / бокс / контейнер на неделю для хранения таблеток и лекарств 4 приема Clear Daswerk
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    Таблетница на 7 дней / органайзер / бокс / контейнер на неделю для хранения таблеток и лекарств 4 приема Clear Daswerk

    Цена 396 ₽ вместо 637
  • Реклама
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  • Копаксон 40 р-р для п/к введ. шприц, 40 мг/мл, 1 мл, 12 шт.
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    Копаксон 40 р-р для п/к введ. шприц, 40 мг/мл, 1 мл, 12 шт.

    Цена 24 645 ₽
  • Бикалутамид-тева таб. п/о плен., 150 мг, 28 шт.
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    Бикалутамид-тева таб. п/о плен., 150 мг, 28 шт.

    Цена 2 411 ₽
  • Таблетница - брелок на день, 1 раздел, контейнер для таблеток металлический маленький (черный матовый)
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    Таблетница - брелок на день, 1 раздел, контейнер для таблеток металлический маленький (черный матовый)

    Цена 235 ₽ вместо 599
  • Лорета таб. п/о плен., 2.5 мг, 30 шт.
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    Лорета таб. п/о плен., 2.5 мг, 30 шт.

    Цена 1 449 ₽
  • Лестродекс таб. п/о плен., 2.5 мг, 30 шт.
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    Лестродекс таб. п/о плен., 2.5 мг, 30 шт.

    Цена 1 959 ₽
  • Фемара таб. п/о плен., 2.5 мг, 30 шт.
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    Фемара таб. п/о плен., 2.5 мг, 30 шт.

    Цена 8 242 ₽
  • Капсулы желатиновые пустые раскрытые Прозрачные Размер 0# 500шт
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    Капсулы желатиновые пустые раскрытые Прозрачные Размер 0# 500шт

    Цена 571 ₽ вместо 1 250
  • Таблетница на 7 дней/контейнер для таблеток и витаминов на 7 дней, Immunit
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    Таблетница на 7 дней/контейнер для таблеток и витаминов на 7 дней, Immunit

    Цена 171 ₽ вместо 189
  • Таблетница «Неделька», русские буквы, 8 секций, круглая
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    Таблетница «Неделька», русские буквы, 8 секций, круглая

    Цена 180 ₽
  • Таблетница ПИЛЮЛЯ На один день 1 шт. бесцветный 10.3 см 7.3 см 2 см 4 шт.
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    Таблетница ПИЛЮЛЯ На один день 1 шт. бесцветный 10.3 см 7.3 см 2 см 4 шт.

    Цена 152 ₽ вместо 154
  • Капсулы желатиновые пустые раскрытые белые Размер 0# 500шт
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    Капсулы желатиновые пустые раскрытые белые Размер 0# 500шт

    Цена 569 ₽ вместо 1 250
  • Таблетница органайзер на неделю утро / день / вечер; Органайзер для таблеток на 7 дней; Карманная аптечка
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1901265275_20/content/content/gallery":{"title":"Таблетница органайзер на неделю утро / день / вечер; Органайзер для таблеток на 7 дней; Карманная аптечка","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/4580925/img_id324533282421137844.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4580925/img_id324533282421137844.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4580925/img_id324533282421137844.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4580925/img_id324533282421137844.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4580925/img_id324533282421137844.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4580925/img_id324533282421137844.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/1581127/img_id4914961834506080269.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/1581127/img_id4914961834506080269.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/1581127/img_id4914961834506080269.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/1581127/img_id4914961834506080269.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/1581127/img_id4914961834506080269.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/1581127/img_id4914961834506080269.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4012150/img_id7503799791064630112.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4012150/img_id7503799791064630112.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4012150/img_id7503799791064630112.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4012150/img_id7503799791064630112.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4012150/img_id7503799791064630112.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4012150/img_id7503799791064630112.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/3934197/img_id4951263920939133144.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/3934197/img_id4951263920939133144.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/3934197/img_id4951263920939133144.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/3934197/img_id4951263920939133144.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/3934197/img_id4951263920939133144.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/3934197/img_id4951263920939133144.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/466729/img_id5124309738158613923.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/466729/img_id5124309738158613923.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/466729/img_id5124309738158613923.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/466729/img_id5124309738158613923.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/466729/img_id5124309738158613923.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/466729/img_id5124309738158613923.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgsQ+Z+J8YzV696GARIaChhyZW1peF9kZXNrdG9wX21vZGVsX2NhcmQyFgj7gsyKBxC9qfSz/AIYlf6/ByDNzj0=","sign":"UPySzK5ShNTW46ZS0qhYMjGcWdb70oGftFKY9K0uRPg="},"target":"model_card"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1901265275_20/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
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    Таблетница органайзер на неделю утро / день / вечер; Органайзер для таблеток на 7 дней; Карманная аптечка

    Цена 781 ₽ вместо 1 890
  • Реклама
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  • Контейнер для хранения/таблетница/кейс для таблеток
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    Контейнер для хранения/таблетница/кейс для таблеток

    Цена 246 ₽ вместо 699
  • Таблетница компактная /органайзер аптечка/ контейнер для таблеток БАД Panda_Home (синего цвета)
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    Таблетница компактная /органайзер аптечка/ контейнер для таблеток БАД Panda_Home (синего цвета)

    Цена 235 ₽ вместо 380
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