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Описание

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Артрозан р-р для в/м введ., 6 мг/мл, 2.5 мл, 3 шт.

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4.9
(21)
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Количество штук в упаковке, шт.: 3

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Коротко о товаре

Артикул Маркета
3176312125
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
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анкилозирующем спондилите; других воспалительных и дегенеративных заболеваниях костно-мышечной системы, таких как артропатии, дорсопатии (например, ишиас, боль в низу спины, плечевой периартрит и другие), сопровождающихся болью."},{"name":"Противопоказания","value":"Гиперчувствительность к действующему веществу и/или любому вспомогательному веществу препарата.\u003Cbr /\u003EГиперчувствительность (в том числе и к другим нестероидным противовоспалительным препаратам).\u003Cbr /\u003EПолное и неполное сочетание бронхиальной астмы, рецидивирующего полипоза носа и околоносовых пазух, ангионевротического отека или крапивницы, вызванных непереносимостью ацетилсалициловой кислоты или других нестероидных противовоспалительных препаратов из-за существующей вероятности перекрестной чувствительности (в том числе в анамнезе).\u003Cbr /\u003EЭрозивно-язвенные поражения желудка и двенадцатиперстной кишки в стадии обострения или недавно перенесенные.\u003Cbr /\u003EВоспалительные заболевания кишечника — болезнь Крона или язвенный колит в стадии обострения.\u003Cbr /\u003EТяжелая печеночная и сердечная недостаточность.\u003Cbr /\u003E Тяжелая почечная недостаточность (если не проводится гемодиализ, клиренс креатинина менее 30 мл/мин, а также при подтвержденной гиперкалиемии).\u003Cbr /\u003EАктивное заболевание печени.\u003Cbr /\u003EАктивное желудочно-кишечное кровотечение, недавно\tперенесенные\u003Cbr /\u003Eцереброваскулярные кровотечения или установленный диагноз заболеваний свертывающей системы крови.\u003Cbr /\u003EВозраст до 18 лет.\u003Cbr /\u003EБеременность.\u003Cbr /\u003EПериод грудного вскармливания.\u003Cbr /\u003EТерапия послеоперационных болей при проведении шунтирования коронарных артерий. Сопутствующая терапия антикоагулянтами, так как есть риск образования внутримышечных гематом."},{"name":"Состав","value":"Действующее вещество: мелоксикам — 6,00 мг; вспомогательные вещества: тетрагидрофурфурил макрогол (гликофурол)\t100,00 мг, полоксамер 188 — 50,00 мг, глицин — 5,00 мг, меглюмин — 3,75 мг, натрия хлорид — 3,00 мг, натрия гидроксида раствор 1 М — до РН 8,2-8,9, вода для инъекций — до 1 мл.\u003Cbr /\u003Eодна ампула (2,5 мл) содержит 15 мг мелоксикама."},{"name":"Действующее вещество","value":"Мелоксикам","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["27144131:28709106"]}}},{"name":"Способ применения и дозы","value":"В/м введение препарата показано в первые 2-3 дня лечения. В дальнейшем лечение продолжают с применением пероральных форм (таблетки). Рекомендуемая доза составляет по 7.5 или 15 мг 1 раз в сутки, в зависимости от интенсивности болей и тяжести воспалительного процесса. Т.к. потенциальный риск побочных реакций зависит от дозы и продолжительности лечения следует использовать наименьшие эффективные дозы и минимально возможным коротким курсом. \u003Cbr\u003EУ пациентов с тяжелой почечной недостаточностью, находящихся на гемодиализе, доза не должна превышать 7.5 мг в день.\u003Cbr\u003EПрепарат вводится посредством глубокой в/м инъекции. Содержимое ампул не следует смешивать в одном шприце с другими лекарственными средствами. Препарат нельзя вводить в/в.\u003Cbr\u003E"},{"name":"Побочные действия","value":"Со стороны пищеварительной системы: более 1% - диспепсия, в т.ч. тошнота, рвота, боль в животе, диарея, запор, метеоризм; 0.1-1% - преходящее повышение активности печеночных трансаминаз, гипербилирубинемия, отрыжка, эзофагит, язва желудка или двенадцатиперстной кишки, желудочно-кишечное кровотечение (скрытое или явное), стоматит; менее 0.1% - перфорация органов ЖКТ, колит, гепатит, гастрит.\u003Cbr\u003EСо стороны органов кроветворения: более 1% - анемия; 0.1-1% - лейкопения, тромбоцитопения.\u003Cbr\u003EСо стороны кожных покровов: более 1% - зуд, кожная сыпь; 0.1-1% - крапивница; менее 0.1% - фотосенсибилизация, буллезные высыпания, многоформная эритема, в т.ч. синдром Стивенса-Джонсона, токсический эпидермальный некролиз. \u003Cbr\u003EСо стороны дыхательной системы: менее 0.1% - бронхоспазм.\u003Cbr\u003EСо стороны ЦНС: более 1% - головокружение, головная боль; 0.1-1% - шум в ушах, сонливость; менее 0.1% - эмоциональная лабильность, спутанность сознания, дезориентация.\u003Cbr\u003EСо стороны сердечно-сосудистой системы: более 1% - периферические отеки; 0.1-1% - повышение уровня АД, сердцебиение, гиперемия лица.\u003Cbr\u003EСо стороны мочевыделительной системы: 0.1-1% - гиперкреатининемия, повышение концентрации сывороточной мочевины; менее 0.1% - острая почечная недостаточность; связь с приемом мелоксикама не установлена - интерстициальный нефрит, альбуминурия, гематурия.\u003Cbr\u003EСо стороны органов чувств: менее 0.1% - конъюнктивит, нечеткость зрения. \u003Cbr\u003EАллергические реакции: менее 0.1% - ангионевротический отек, анафилактические, анафилактоидные реакции.\u003Cbr\u003E"},{"name":"Фармакологическое действие","value":"Мелоксикам является нестероидным противовоспалительным препаратом (НПВП), относится к производным эноловой кислоты и оказывает противовоспалительное, анальгетическое и жаропонижающее действие. Выраженное противовоспалительное действие мелоксикама установлено на всех стандартных моделях воспаления. Механизм действия мелоксикама состоит в его способности ингибировать синтез простагландинов - известных медиаторов воспаления. Мелоксикам in vivo ингибирует синтез простагландинов в месте воспаления в большей степени, чем в слизистой оболочке желудка или почках.\u003Cbr /\u003EЭти различия связаны с более селективным ингибированием циклооксигеназы-2 (ЦОГ-2) по сравнению с циклооксигеназой-1 (ЦОГ-1). Считается, что ингибирование ЦОГ-2 обеспечивает терапевтические действия НПВП, тогда как ингибирование постоянно присутствующего изофермента ЦОГ-1 может быть ответственно за побочные действия со стороны желудка и почек. Селективность мелоксикама в отношении ЦОГ-2 подтверждена в различных тест-системах, как in vitro, так и in vivo. Селективная способность мелоксикама ингибировать ЦОГ-2 показана при использовании в качестве тест-системы цельной крови человека in vitro. Установлено, что мелоксикам (в дозах 7,5 и 15 мг) активнее ингибировал ЦОГ-2, оказывая большее ингибирующее влияние на продукцию простагландина Е2, стимулируемую липополисахаридом (реакция, контролируемая ЦОГ-2), чем на продукцию тромбоксана, участвующего в процессе свертывания крови (реакция, контролируемая ЦОГ-1). Эти эффекты зависели от величины дозы. В исследованиях ex vivo показано, что мелоксикам (в дозах 7,5 мг и 15 мг) не оказывает влияния на агрегацию тромбоцитов и время кровотечения.\u003Cbr /\u003E В клинических исследованиях побочные эффекты со стороны желудочно-кишечного тракта (ЖКТ) в целом возникали реже при приеме мелоксикама 7,5 и 15 мг, чем при приеме других НПВП, с которыми проводилось сравнение. Это различие в частоте побочных эффектов со стороны ЖКТ в основном связано с тем, что при приеме мелоксикама реже наблюдались такие явления как диспепсия, рвота, тошнота, абдоминальные боли. Частота перфораций в верхних отделах ЖКТ, язв и кровотечений, которые связывались с применением мелоксикама, была низкой и зависела от величины дозы препарата."},{"name":"Фармакологическая группа","value":"нестероидный противовоспалительный препарат (НПВП)"},{"name":"Форма выпуска","value":"раствор для инъекций"},{"name":"Способ применения/введения","value":"парентеральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["35947170:36763748"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"В защищенном от света месте при температуре не выше 25°С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы: нарушение сознания, тошнота, рвота, боли в эпигастрии, кровотечение из ЖКТ, острая почечная недостаточность, печеночная недостаточность, остановка дыхания, асистолия.\u003Cbr\u003EЛечение: специфических антидотов и антагонистов нет. Форсированный диурез, защелачивание мочи, гемодиализ малоэффективны из-за высокой связи препарата с белками крови.\u003Cbr\u003E"},{"name":"Применение при беременности и кормлении грудью","value":"Применение препарата Артрозан противопоказано во время беременности.\u003Cbr /\u003EКак препарат, ингибирующий синтез циклооксигеназы/простагландина, мелоксикам может оказывать влияние на фертильность, и поэтому не рекомендуется женщинам, планирующим беременность. Мелоксикам может приводить к задержке овуляции. В связи с этим у женщин, имеющих проблемы с зачатием и проходящим обследование по поводу подобных проблем, рекомендуется отмена приема препарата.\u003Cbr /\u003EПериод грудного вскармливания\u003Cbr /\u003EИзвестно, что НПВП проникают в грудное молоко, поэтому применение препарата Артрозан в период грудного вскармливания противопоказано."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Применение препарата может вызывать возникновение головной боли, головокружения и сонливости. При возникновении этих явлений следует отказаться от управления транспортными средствами и выполнения других потенциально опасных видов деятельности, требующих повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"\u003Cbr /\u003E С осторожностью\u003Cbr /\u003EЗаболевания желудочно-кишечного тракта в анамнезе (наличие инфекции Helicobacter pylori).\u003Cbr /\u003EХроническая сердечная недостаточность.\u003Cbr /\u003EПочечная недостаточность (клиренс креатинина 30-60 мл/мин).\u003Cbr /\u003EИшемическая болезнь сердца.\u003Cbr /\u003EЦереброваскулярные заболевания.\u003Cbr /\u003EДислипидемия/гиперлипидемия.\u003Cbr /\u003EСахарный диабет.\u003Cbr /\u003EСопутствующая терапия антикоагулянтами, пероральными глюкокортикостероидами, антиагрегантами, селективными ингибиторами обратного захвата серотонина.\u003Cbr /\u003EЗаболевания периферических артерий.\u003Cbr /\u003EПожилой возраст.\u003Cbr /\u003EДлительное применение НПВП.\u003Cbr /\u003EКурение.\u003Cbr /\u003EЧастое употребление алкоголя.\u003Cbr /\u003EПрепарат может изменять свойства тромбоцитов, однако не заменяет профилактического действия ацетилсалициловой кислоты при сердечно-сосудистых заболеваниях.\u003Cbr\u003EСледует соблюдать осторожность при применении препарата пациентами, в анамнезе которых есть указания на язвенную болезнь желудка и двенадцатиперстной кишки, и пациентами, находящимися на антикоагулянтной терапии. У таких пациентов повышен риск возникновения эрозивно-язвенных заболеваний ЖКТ.\u003Cbr\u003EСледует соблюдать осторожность и контролировать суточный диурез и функцию почек при применении препарата у пожилых и больных с уменьшенным ОЦК и сниженной клубочковой фильтрацией (дегидратация, хроническая сердечная недостаточность, цирроз печени, нефротический синдром, клинически выраженные заболевания почек, прием диуретиков, обезвоживание после больших хирургических операций).\u003Cbr\u003EПри появлении признаков поражения печени (кожный зуд, пожелтение кожных покровов, тошнота, рвота, боли в животе, потемнение мочи, стойкое и существенное повышение уровня трансаминаз и изменение других показателей функции печени) прием препарата следует прекратить и обратиться к лечащему врачу.\u003Cbr\u003EПосле двух недель применения препарата необходим контроль активности печеночных ферментов.\u003Cbr\u003EУ пациентов с незначительным или умеренным снижением функции почек (КК≥30 мл/мин) коррекция дозы не требуется.\u003Cbr\u003EПациенты, принимающие одновременно мочегонные средства и мелоксикам, должны принимать достаточное количество жидкости.\u003Cbr\u003EПри возникновении аллергических реакций (зуд, кожная сыпь, крапивница, фотосенсибилизация) в процессе лечения необходимо обратиться к врачу с целью решения вопроса о прекращении приема препарата.\u003Cbr\u003EМелоксикам, как и другие НПВП, может маскировать симптомы инфекционных заболеваний.\u003Cbr\u003EПрименение мелоксикама, как и других препаратов, блокирующих синтез простагландинов, может влиять на фертильность, поэтому не рекомендуется для приема женщинам, планирующим беременность.\u003Cbr\u003EНе следует применять препарат одновременно с другими НПВП."},{"name":"Взаимодействие","value":"При одновременном применении с другими НПВП (в т.ч. с ацетилсалициловой кислотой) увеличивается риск возникновения эрозивно-язвенных поражений и желудочно-кишечных кровотечений. \u003Cbr\u003EПри одновременном применении с гипотензивными препаратами возможно снижение эффективности действия последних. \u003Cbr\u003EПри одновременном применении с препаратами лития возможно развитие кумуляции лития и увеличение его токсического действия (рекомендуется контроль концентрации лития в крови). \u003Cbr\u003EПри одновременном применении с метотрексатом усиливается побочное действие последнего на кроветворную систему (опасность возникновения анемии и лейкопении, показано периодическое проведение общего анализа крови). \u003Cbr\u003EПри одновременном применении с диуретиками и циклоспорином возрастает риск развития почечной недостаточности. \u003Cbr\u003EПри одновременном применении с внутриматочными контрацептивными средствами возможно снижение эффективности действия последних. \u003Cbr\u003EПри одновременном применении с антикоагулянтами (гепарин, варфарин), тромболитическими препаратами (стрептокиназа, фибринолизин), и антиагрегантами (тиклопидин, клопидогрел, ацетисалициловая кислота) увеличивается риск развития кровотечений (необходим периодический контроль показателей свертываемости крови). \u003Cbr\u003EПри одновременном применении с колестирамином ускоряется выведение мелоксикама через ЖКТ. \u003Cbr\u003EПри одновременном применении с селективными ингибиторами обратного захвата серотонина возрастает риск развития желудочно-кишечных кровотечений."},{"name":"Регистрационный номер","value":"ЛCP-004856/10,\nЛП-№(000537)-(РГ-RU)"},{"name":"Дата государственной регистрации","value":"11.08.2020,\n01.02.2022"},{"name":"Владелец регистрационного удостоверения","value":"Фармстандарт-УфаВИТА","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["34324371:35649313","7893318:16146734"]}}},{"name":"Изготовитель","value":"Фармстандарт-УфаВИТА"},{"name":"Фасовщик","value":"Фармстандарт-УфаВИТА"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Артрозан","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["17796364:18028448"]}}},{"name":"Срок годности","value":"61 мес."}]}},"fullSpecsGrouped":{"82824157650221744":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"опорно-двигательная система"},{"name":"Назначение","value":"анкилозирующий спондилит, остеоартрит, ревматоидный артрит, спондилоартроз"},{"name":"Показания к применению","value":"Стартовая терапия и краткосрочное симптоматическое лечение при:\u003Cbr /\u003Eостеоартрите (артроз, дегенеративные заболевания суставов);\u003Cbr /\u003Eревматоидном артрите; анкилозирующем спондилите; других воспалительных и дегенеративных заболеваниях костно-мышечной системы, таких как артропатии, дорсопатии (например, ишиас, боль в низу спины, плечевой периартрит и другие), сопровождающихся болью."},{"name":"Противопоказания","value":"Гиперчувствительность к действующему веществу и/или любому вспомогательному веществу препарата.\u003Cbr /\u003EГиперчувствительность (в том числе и к другим нестероидным противовоспалительным препаратам).\u003Cbr /\u003EПолное и неполное сочетание бронхиальной астмы, рецидивирующего полипоза носа и околоносовых пазух, ангионевротического отека или крапивницы, вызванных непереносимостью ацетилсалициловой кислоты или других нестероидных противовоспалительных препаратов из-за существующей вероятности перекрестной чувствительности (в том числе в анамнезе).\u003Cbr /\u003EЭрозивно-язвенные поражения желудка и двенадцатиперстной кишки в стадии обострения или недавно перенесенные.\u003Cbr /\u003EВоспалительные заболевания кишечника — болезнь Крона или язвенный колит в стадии обострения.\u003Cbr /\u003EТяжелая печеночная и сердечная недостаточность.\u003Cbr /\u003E Тяжелая почечная недостаточность (если не проводится гемодиализ, клиренс креатинина менее 30 мл/мин, а также при подтвержденной гиперкалиемии).\u003Cbr /\u003EАктивное заболевание печени.\u003Cbr /\u003EАктивное желудочно-кишечное кровотечение, недавно\tперенесенные\u003Cbr /\u003Eцереброваскулярные кровотечения или установленный диагноз заболеваний свертывающей системы крови.\u003Cbr /\u003EВозраст до 18 лет.\u003Cbr /\u003EБеременность.\u003Cbr /\u003EПериод грудного вскармливания.\u003Cbr /\u003EТерапия послеоперационных болей при проведении шунтирования коронарных артерий. Сопутствующая терапия антикоагулянтами, так как есть риск образования внутримышечных гематом."},{"name":"Состав","value":"Действующее вещество: мелоксикам — 6,00 мг; вспомогательные вещества: тетрагидрофурфурил макрогол (гликофурол)\t100,00 мг, полоксамер 188 — 50,00 мг, глицин — 5,00 мг, меглюмин — 3,75 мг, натрия хлорид — 3,00 мг, натрия гидроксида раствор 1 М — до РН 8,2-8,9, вода для инъекций — до 1 мл.\u003Cbr /\u003Eодна ампула (2,5 мл) содержит 15 мг мелоксикама."},{"name":"Действующее вещество","value":"Мелоксикам"},{"name":"Способ применения и дозы","value":"В/м введение препарата показано в первые 2-3 дня лечения. В дальнейшем лечение продолжают с применением пероральных форм (таблетки). Рекомендуемая доза составляет по 7.5 или 15 мг 1 раз в сутки, в зависимости от интенсивности болей и тяжести воспалительного процесса. Т.к. потенциальный риск побочных реакций зависит от дозы и продолжительности лечения следует использовать наименьшие эффективные дозы и минимально возможным коротким курсом. \u003Cbr\u003EУ пациентов с тяжелой почечной недостаточностью, находящихся на гемодиализе, доза не должна превышать 7.5 мг в день.\u003Cbr\u003EПрепарат вводится посредством глубокой в/м инъекции. Содержимое ампул не следует смешивать в одном шприце с другими лекарственными средствами. Препарат нельзя вводить в/в.\u003Cbr\u003E"},{"name":"Побочные действия","value":"Со стороны пищеварительной системы: более 1% - диспепсия, в т.ч. тошнота, рвота, боль в животе, диарея, запор, метеоризм; 0.1-1% - преходящее повышение активности печеночных трансаминаз, гипербилирубинемия, отрыжка, эзофагит, язва желудка или двенадцатиперстной кишки, желудочно-кишечное кровотечение (скрытое или явное), стоматит; менее 0.1% - перфорация органов ЖКТ, колит, гепатит, гастрит.\u003Cbr\u003EСо стороны органов кроветворения: более 1% - анемия; 0.1-1% - лейкопения, тромбоцитопения.\u003Cbr\u003EСо стороны кожных покровов: более 1% - зуд, кожная сыпь; 0.1-1% - крапивница; менее 0.1% - фотосенсибилизация, буллезные высыпания, многоформная эритема, в т.ч. синдром Стивенса-Джонсона, токсический эпидермальный некролиз. \u003Cbr\u003EСо стороны дыхательной системы: менее 0.1% - бронхоспазм.\u003Cbr\u003EСо стороны ЦНС: более 1% - головокружение, головная боль; 0.1-1% - шум в ушах, сонливость; менее 0.1% - эмоциональная лабильность, спутанность сознания, дезориентация.\u003Cbr\u003EСо стороны сердечно-сосудистой системы: более 1% - периферические отеки; 0.1-1% - повышение уровня АД, сердцебиение, гиперемия лица.\u003Cbr\u003EСо стороны мочевыделительной системы: 0.1-1% - гиперкреатининемия, повышение концентрации сывороточной мочевины; менее 0.1% - острая почечная недостаточность; связь с приемом мелоксикама не установлена - интерстициальный нефрит, альбуминурия, гематурия.\u003Cbr\u003EСо стороны органов чувств: менее 0.1% - конъюнктивит, нечеткость зрения. \u003Cbr\u003EАллергические реакции: менее 0.1% - ангионевротический отек, анафилактические, анафилактоидные реакции.\u003Cbr\u003E"},{"name":"Фармакологическое действие","value":"Мелоксикам является нестероидным противовоспалительным препаратом (НПВП), относится к производным эноловой кислоты и оказывает противовоспалительное, анальгетическое и жаропонижающее действие. Выраженное противовоспалительное действие мелоксикама установлено на всех стандартных моделях воспаления. Механизм действия мелоксикама состоит в его способности ингибировать синтез простагландинов - известных медиаторов воспаления. Мелоксикам in vivo ингибирует синтез простагландинов в месте воспаления в большей степени, чем в слизистой оболочке желудка или почках.\u003Cbr /\u003EЭти различия связаны с более селективным ингибированием циклооксигеназы-2 (ЦОГ-2) по сравнению с циклооксигеназой-1 (ЦОГ-1). Считается, что ингибирование ЦОГ-2 обеспечивает терапевтические действия НПВП, тогда как ингибирование постоянно присутствующего изофермента ЦОГ-1 может быть ответственно за побочные действия со стороны желудка и почек. Селективность мелоксикама в отношении ЦОГ-2 подтверждена в различных тест-системах, как in vitro, так и in vivo. Селективная способность мелоксикама ингибировать ЦОГ-2 показана при использовании в качестве тест-системы цельной крови человека in vitro. Установлено, что мелоксикам (в дозах 7,5 и 15 мг) активнее ингибировал ЦОГ-2, оказывая большее ингибирующее влияние на продукцию простагландина Е2, стимулируемую липополисахаридом (реакция, контролируемая ЦОГ-2), чем на продукцию тромбоксана, участвующего в процессе свертывания крови (реакция, контролируемая ЦОГ-1). Эти эффекты зависели от величины дозы. В исследованиях ex vivo показано, что мелоксикам (в дозах 7,5 мг и 15 мг) не оказывает влияния на агрегацию тромбоцитов и время кровотечения.\u003Cbr /\u003E В клинических исследованиях побочные эффекты со стороны желудочно-кишечного тракта (ЖКТ) в целом возникали реже при приеме мелоксикама 7,5 и 15 мг, чем при приеме других НПВП, с которыми проводилось сравнение. Это различие в частоте побочных эффектов со стороны ЖКТ в основном связано с тем, что при приеме мелоксикама реже наблюдались такие явления как диспепсия, рвота, тошнота, абдоминальные боли. Частота перфораций в верхних отделах ЖКТ, язв и кровотечений, которые связывались с применением мелоксикама, была низкой и зависела от величины дозы препарата."},{"name":"Фармакологическая группа","value":"нестероидный противовоспалительный препарат (НПВП)"},{"name":"Форма выпуска","value":"раствор для инъекций"},{"name":"Способ применения/введения","value":"парентеральный"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"В защищенном от света месте при температуре не выше 25°С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы: нарушение сознания, тошнота, рвота, боли в эпигастрии, кровотечение из ЖКТ, острая почечная недостаточность, печеночная недостаточность, остановка дыхания, асистолия.\u003Cbr\u003EЛечение: специфических антидотов и антагонистов нет. Форсированный диурез, защелачивание мочи, гемодиализ малоэффективны из-за высокой связи препарата с белками крови.\u003Cbr\u003E"},{"name":"Применение при беременности и кормлении грудью","value":"Применение препарата Артрозан противопоказано во время беременности.\u003Cbr /\u003EКак препарат, ингибирующий синтез циклооксигеназы/простагландина, мелоксикам может оказывать влияние на фертильность, и поэтому не рекомендуется женщинам, планирующим беременность. Мелоксикам может приводить к задержке овуляции. В связи с этим у женщин, имеющих проблемы с зачатием и проходящим обследование по поводу подобных проблем, рекомендуется отмена приема препарата.\u003Cbr /\u003EПериод грудного вскармливания\u003Cbr /\u003EИзвестно, что НПВП проникают в грудное молоко, поэтому применение препарата Артрозан в период грудного вскармливания противопоказано."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Применение препарата может вызывать возникновение головной боли, головокружения и сонливости. При возникновении этих явлений следует отказаться от управления транспортными средствами и выполнения других потенциально опасных видов деятельности, требующих повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"\u003Cbr /\u003E С осторожностью\u003Cbr /\u003EЗаболевания желудочно-кишечного тракта в анамнезе (наличие инфекции Helicobacter pylori).\u003Cbr /\u003EХроническая сердечная недостаточность.\u003Cbr /\u003EПочечная недостаточность (клиренс креатинина 30-60 мл/мин).\u003Cbr /\u003EИшемическая болезнь сердца.\u003Cbr /\u003EЦереброваскулярные заболевания.\u003Cbr /\u003EДислипидемия/гиперлипидемия.\u003Cbr /\u003EСахарный диабет.\u003Cbr /\u003EСопутствующая терапия антикоагулянтами, пероральными глюкокортикостероидами, антиагрегантами, селективными ингибиторами обратного захвата серотонина.\u003Cbr /\u003EЗаболевания периферических артерий.\u003Cbr /\u003EПожилой возраст.\u003Cbr /\u003EДлительное применение НПВП.\u003Cbr /\u003EКурение.\u003Cbr /\u003EЧастое употребление алкоголя.\u003Cbr /\u003EПрепарат может изменять свойства тромбоцитов, однако не заменяет профилактического действия ацетилсалициловой кислоты при сердечно-сосудистых заболеваниях.\u003Cbr\u003EСледует соблюдать осторожность при применении препарата пациентами, в анамнезе которых есть указания на язвенную болезнь желудка и двенадцатиперстной кишки, и пациентами, находящимися на антикоагулянтной терапии. У таких пациентов повышен риск возникновения эрозивно-язвенных заболеваний ЖКТ.\u003Cbr\u003EСледует соблюдать осторожность и контролировать суточный диурез и функцию почек при применении препарата у пожилых и больных с уменьшенным ОЦК и сниженной клубочковой фильтрацией (дегидратация, хроническая сердечная недостаточность, цирроз печени, нефротический синдром, клинически выраженные заболевания почек, прием диуретиков, обезвоживание после больших хирургических операций).\u003Cbr\u003EПри появлении признаков поражения печени (кожный зуд, пожелтение кожных покровов, тошнота, рвота, боли в животе, потемнение мочи, стойкое и существенное повышение уровня трансаминаз и изменение других показателей функции печени) прием препарата следует прекратить и обратиться к лечащему врачу.\u003Cbr\u003EПосле двух недель применения препарата необходим контроль активности печеночных ферментов.\u003Cbr\u003EУ пациентов с незначительным или умеренным снижением функции почек (КК≥30 мл/мин) коррекция дозы не требуется.\u003Cbr\u003EПациенты, принимающие одновременно мочегонные средства и мелоксикам, должны принимать достаточное количество жидкости.\u003Cbr\u003EПри возникновении аллергических реакций (зуд, кожная сыпь, крапивница, фотосенсибилизация) в процессе лечения необходимо обратиться к врачу с целью решения вопроса о прекращении приема препарата.\u003Cbr\u003EМелоксикам, как и другие НПВП, может маскировать симптомы инфекционных заболеваний.\u003Cbr\u003EПрименение мелоксикама, как и других препаратов, блокирующих синтез простагландинов, может влиять на фертильность, поэтому не рекомендуется для приема женщинам, планирующим беременность.\u003Cbr\u003EНе следует применять препарат одновременно с другими НПВП."},{"name":"Взаимодействие","value":"При одновременном применении с другими НПВП (в т.ч. с ацетилсалициловой кислотой) увеличивается риск возникновения эрозивно-язвенных поражений и желудочно-кишечных кровотечений. \u003Cbr\u003EПри одновременном применении с гипотензивными препаратами возможно снижение эффективности действия последних. \u003Cbr\u003EПри одновременном применении с препаратами лития возможно развитие кумуляции лития и увеличение его токсического действия (рекомендуется контроль концентрации лития в крови). \u003Cbr\u003EПри одновременном применении с метотрексатом усиливается побочное действие последнего на кроветворную систему (опасность возникновения анемии и лейкопении, показано периодическое проведение общего анализа крови). \u003Cbr\u003EПри одновременном применении с диуретиками и циклоспорином возрастает риск развития почечной недостаточности. \u003Cbr\u003EПри одновременном применении с внутриматочными контрацептивными средствами возможно снижение эффективности действия последних. \u003Cbr\u003EПри одновременном применении с антикоагулянтами (гепарин, варфарин), тромболитическими препаратами (стрептокиназа, фибринолизин), и антиагрегантами (тиклопидин, клопидогрел, ацетисалициловая кислота) увеличивается риск развития кровотечений (необходим периодический контроль показателей свертываемости крови). \u003Cbr\u003EПри одновременном применении с колестирамином ускоряется выведение мелоксикама через ЖКТ. \u003Cbr\u003EПри одновременном применении с селективными ингибиторами обратного захвата серотонина возрастает риск развития желудочно-кишечных кровотечений."},{"name":"Регистрационный номер","value":"ЛCP-004856/10,\nЛП-№(000537)-(РГ-RU)"},{"name":"Дата государственной регистрации","value":"11.08.2020,\n01.02.2022"},{"name":"Владелец регистрационного удостоверения","value":"Фармстандарт-УфаВИТА"},{"name":"Изготовитель","value":"Фармстандарт-УфаВИТА"},{"name":"Фасовщик","value":"Фармстандарт-УфаВИТА"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Артрозан"},{"name":"Срок годности","value":"61 мес."}]}],"transitionId":"tr_9646927682124458532"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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162 ₽

Скидка: 24%
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Вместо:212 ₽
  • 18-20 июня, самовывоз • 0 ₽
POLZAru
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  • Коллаген для суставов капс., 120 шт.
    –21 %
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    Коллаген для суставов капс., 120 шт.

    Рейтинг товара: 4.7 из 5
    на основе 684 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 754 ₽ вместо 770
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  • Артнео капс., 35 г, 30 шт., нейтральный, 1 уп.
    –68 %
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    Артнео капс., 35 г, 30 шт., нейтральный, 1 уп.

    Рейтинг товара: 4.8 из 5
    на основе 300 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 1 362 ₽ вместо 1 390
    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  • Артроцин капс., 36 шт., 1 уп.
    –42 %
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    Артроцин капс., 36 шт., 1 уп.

    Рейтинг товара: 4.7 из 5
    на основе 38 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 497 ₽ вместо 507
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  • Глюкозамин-хондроитиновый комплекс капс., 90 шт.
    –1 %
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    Глюкозамин-хондроитиновый комплекс капс., 90 шт.

    Рейтинг товара: 4.8 из 5
    на основе 48 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 396 ₽ вместо 400
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  • Плексатрон имплантат коллаген-содержащий для в/суст. и периартикул. введ. фл., 100 мкг/2 мл, 2 мл, 5 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-0lcydc1q6is9/toggleWishlist":{"skuId":"904005016","productId":1778175346,"offerId":"Oy4pKuBpFvN9T9RrtvYH5Q","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQwrPQ0t6OsaN6EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYI8przzwYQmIuIrwMYxtqtCiDn3MEH","sign":"ZpAiUML2no3fTH4Qebxa5h4EMkoUZ81mqD/7l9xX3Tc="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-0lcydc1q6is9/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Плексатрон имплантат коллаген-содержащий для в/суст. и периартикул. введ. фл., 100 мкг/2 мл, 2 мл, 5 шт.

    Рейтинг товара: 4.8 из 5
    на основе 78 оценок
    Цена 4 500 ₽
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  • Хонда капс., 30 шт., 1 уп.
    –1 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-jpb085xb46t/toggleWishlist":{"skuId":"265134447","productId":1778174679,"offerId":"Q4gvOLTcJYEJJFkezUtWyg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQwrPQ0t6OsaN6EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI15XzzwYQ78K2fhjVu6EGIOfcwQc=","sign":"QIZwluZq7+SSLirjAdOsB1vxKbupePtzn+Jn7fOZK44="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-jpb085xb46t/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Хонда капс., 30 шт., 1 уп.

    Рейтинг товара: 4.8 из 5
    на основе 9 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 407 ₽ вместо 411
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  • Артролонг капс., 125 шт., нейтральный, 1 уп.
    –58 %
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    Артролонг капс., 125 шт., нейтральный, 1 уп.

    Рейтинг товара: 4.6 из 5
    на основе 39 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 416 ₽ вместо 429
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  • Лошадиное здоровье Настоящий бычий хондроитин с глюкозамином крем д/нар. прим., 200 мл, 1 уп.
    –1 %
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    Лошадиное здоровье Настоящий бычий хондроитин с глюкозамином крем д/нар. прим., 200 мл, 1 уп.

    Рейтинг товара: 4.5 из 5
    на основе 45 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 241 ₽ вместо 243
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  • Гиалуром р-р для в/суст. введ. шприц, 1.5, 2 мл, 26 г, 1 шт., 1 уп.
    –1 %
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    Гиалуром р-р для в/суст. введ. шприц, 1.5, 2 мл, 26 г, 1 шт., 1 уп.

    Рейтинг товара: 4.8 из 5
    на основе 34 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 6 829 ₽ вместо 6 898
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  • Армавискон форте р-р для в/суст. введ. шприц, 2.3%, 3 мл, 1 шт.
    –1 %
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    Армавискон форте р-р для в/суст. введ. шприц, 2.3%, 3 мл, 1 шт.

    Рейтинг товара: 4.8 из 5
    на основе 74 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 16 893 ₽ вместо 17 064
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  • Армавискон Platinum р-р для в/суст. введ., 3%, 3 мл, 1 шт.
    –35 %
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    Армавискон Platinum р-р для в/суст. введ., 3%, 3 мл, 1 шт.

    Рейтинг товара: 4.7 из 5
    на основе 172 оценки
    Цена 18 404 ₽ вместо 28 170
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Инструкция

Показания к применению

Стартовая терапия и краткосрочное симптоматическое лечение при:
остеоартрите (артроз, дегенеративные заболевания суставов);
ревматоидном артрите; анкилозирующем спондилите; других воспалительных и дегенеративных заболеваниях костно-мышечной системы, таких как артропатии, дорсопатии (например, ишиас, боль в низу спины, плечевой периартрит и другие), сопровождающихся болью.

Противопоказания

Гиперчувствительность к действующему веществу и/или любому вспомогательному веществу препарата.
Гиперчувствительность (в том числе и к другим нестероидным противовоспалительным препаратам).
Полное и неполное сочетание бронхиальной астмы, рецидивирующего полипоза носа и околоносовых пазух, ангионевротического отека или крапивницы, вызванных непереносимостью ацетилсалициловой кислоты или других нестероидных противовоспалительных препаратов из-за существующей вероятности перекрестной чувствительности (в том числе в анамнезе).
Эрозивно-язвенные поражения желудка и двенадцатиперстной кишки в стадии обострения или недавно перенесенные.
Воспалительные заболевания кишечника — болезнь Крона или язвенный колит в стадии обострения.
Тяжелая печеночная и сердечная недостаточность.
Тяжелая почечная недостаточность (если не проводится гемодиализ, клиренс креатинина менее 30 мл/мин, а также при подтвержденной гиперкалиемии).
Активное заболевание печени.
Активное желудочно-кишечное кровотечение, недавно перенесенные
цереброваскулярные кровотечения или установленный диагноз заболеваний свертывающей системы крови.
Возраст до 18 лет.
Беременность.
Период грудного вскармливания.
Терапия послеоперационных болей при проведении шунтирования коронарных артерий. Сопутствующая терапия антикоагулянтами, так как есть риск образования внутримышечных гематом.

Способ применения и дозы

В/м введение препарата показано в первые 2-3 дня лечения. В дальнейшем лечение продолжают с применением пероральных форм (таблетки). Рекомендуемая доза составляет по 7.5 или 15 мг 1 раз в сутки, в зависимости от интенсивности болей и тяжести воспалительного процесса. Т.к. потенциальный риск побочных реакций зависит от дозы и продолжительности лечения следует использовать наименьшие эффективные дозы и минимально возможным коротким курсом.
У пациентов с тяжелой почечной недостаточностью, находящихся на гемодиализе, доза не должна превышать 7.5 мг в день.
Препарат вводится посредством глубокой в/м инъекции. Содержимое ампул не следует смешивать в одном шприце с другими лекарственными средствами. Препарат нельзя вводить в/в.
Полная инструкция
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Артрозан р-р для в/м введ.
Артрозан р-р для в/м введ., 6 мг/мл, 2.5 мл, 3 шт.
4.9
(21)
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4 вопроса
Инструкция

162 ₽

Скидка: 24%
–24 %
Вместо:212 ₽
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4.9
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У продавца:21 оценка·5 отзывов
У всех продавцов:95 оценок·30 отзывов
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user avatar
Месяц назад • Людмила Дулова • Куплен на Маркете
Достоинства: снимает боль в спине
Недостатки: стал пропадать в аптеках
Комментарий: помогает лучше мелоксикама под другим названием,
user avatar
Месяц назад • D Nik • Куплен на Маркете
Достоинства: Достойная замена более дорогому лекарству
Недостатки: Нет
user avatar
3 месяца назад • Сергей Ф. • Куплен на Маркете
Достоинства: цена
Недостатки: нет
Комментарий: хороший,недорогой ,эффективный препарат
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    Цена 79 ₽ вместо 80
  • БиоГая Пробиотик капли детск. фл., 5 мл, 1 уп.
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    БиоГая Пробиотик капли детск. фл., 5 мл, 1 уп.

    Цена 1 752 ₽ вместо 3 500
  • Глюкозамин-хондроитиновый комплекс капс., 90 шт.
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    Глюкозамин-хондроитиновый комплекс капс., 90 шт.

    Цена 396 ₽ вместо 400
  • Ревмафлекс капс., 60 шт., нейтральный, 1 уп.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778175162_4/content/content/gallery":{"title":"Ревмафлекс капс., 60 шт., нейтральный, 1 уп.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/5235182/img_id7240902984627641170.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5235182/img_id7240902984627641170.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5235182/img_id7240902984627641170.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5235182/img_id7240902984627641170.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5235182/img_id7240902984627641170.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5235182/img_id7240902984627641170.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/1927422/img_id7935672565540282125.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/1927422/img_id7935672565540282125.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/1927422/img_id7935672565540282125.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/1927422/img_id7935672565540282125.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/1927422/img_id7935672565540282125.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/1927422/img_id7935672565540282125.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQwrPQ0t6OsaN6EhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCLqZ888GELmypb4CGNW7oQYg59zBBw==","sign":"iczvyT9QiS181MbMHkFxrkXTCFOalQ0ufoOWSOsoP0A="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778175162_4/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
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    Ревмафлекс капс., 60 шт., нейтральный, 1 уп.

    Цена 772 ₽ вместо 950
  • Плексатрон имплантат коллаген-содержащий для в/суст. и периартикул. введ. фл., 100 мкг/2 мл, 2 мл, 5 шт.
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    Плексатрон имплантат коллаген-содержащий для в/суст. и периартикул. введ. фл., 100 мкг/2 мл, 2 мл, 5 шт.

    Цена 4 500 ₽
  • Фенибут таб., 250 мг, 10 шт.
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    Фенибут таб., 250 мг, 10 шт.

    Цена 92 ₽
  • Препарат для укрепления связок и суставов Universal Nutrition Animal Flex, 30 шт.
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    Препарат для укрепления связок и суставов Universal Nutrition Animal Flex, 30 шт.

    Цена 3 643 ₽ вместо 3 680
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    Реклама
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  • Коллаген для суставов капс., 120 шт.
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    Коллаген для суставов капс., 120 шт.

    Цена 754 ₽ вместо 950
  • Артнео капс., 35 г, 30 шт., нейтральный, 1 уп.
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    Артнео капс., 35 г, 30 шт., нейтральный, 1 уп.

    Цена 1 362 ₽ вместо 4 225
  • Лимфомиозот капли д/вн. приема, 30 мл
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    Лимфомиозот капли д/вн. приема, 30 мл

    Цена 910 ₽ вместо 1 081
  • Марля медицинская повышенной плотности, отрез 3 метра
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    Марля медицинская повышенной плотности, отрез 3 метра

    Цена 157 ₽ вместо 199
  • Эвалар Чай Эвалар БИО при повышенном содержании мочевой кислоты, 20 фильтр-пакетов
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    Эвалар Чай Эвалар БИО при повышенном содержании мочевой кислоты, 20 фильтр-пакетов

    Цена 194 ₽ вместо 224
  • Дипроспан сусп. д/ин., 2мг+5мг/мл, 1 мл, 1 шт.
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    Дипроспан сусп. д/ин., 2мг+5мг/мл, 1 мл, 1 шт.

    Цена 796 ₽
  • Хонда капс., 30 шт., 1 уп.
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    Хонда капс., 30 шт., 1 уп.

    Цена 407 ₽ вместо 411
  • Левомеколь мазь д/нар. прим., 40 мг/г+7.5 мг/г, 40 мл, 40 г
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    Левомеколь мазь д/нар. прим., 40 мг/г+7.5 мг/г, 40 мл, 40 г

    Цена 201 ₽ вместо 203
  • Гилан Комфорт увлажн. гл. р-р, 0.18%, 0.4 мл, 30 шт.
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    Гилан Комфорт увлажн. гл. р-р, 0.18%, 0.4 мл, 30 шт.

    Цена 396 ₽
  • Нафтизин капли наз. фл.-кап., 0.1%, 10 мл
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    Нафтизин капли наз. фл.-кап., 0.1%, 10 мл

    Цена 18 ₽
  • Жидкий пластырь Fixplast c пантенолом, 60 мл
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    Жидкий пластырь Fixplast c пантенолом, 60 мл

    Цена 355 ₽ вместо 399
  • Гилан ультра комфорт увлажн. гл. р-р, 0.3%, 0.4 мл, 50 г, 10 шт.
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    Гилан ультра комфорт увлажн. гл. р-р, 0.3%, 0.4 мл, 50 г, 10 шт.

    Цена 288 ₽ вместо 331
  • Салфетка с нашатырем для стимуляции дыхания 3х6, 20 шт
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    Салфетка с нашатырем для стимуляции дыхания 3х6, 20 шт

    Цена 199 ₽ вместо 250
  • Акваназаль Софт аэр., 150 мл, 120 г, 1 шт., 1 уп.
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    Акваназаль Софт аэр., 150 мл, 120 г, 1 шт., 1 уп.

    Цена 306 ₽ вместо 520
  • Артроцин капс., 36 шт., 1 уп.
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    Артроцин капс., 36 шт., 1 уп.

    Цена 497 ₽ вместо 853
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