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Описание

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Дермовейт крем, 0,05%, 25 мл, 25 г

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4.9
(17)
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Коротко о товаре

Артикул Маркета
3123170508
Тип препарата
Назначение
Действующее вещество
Возраст
от 1 года
Инструкция
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Длительность применения - до появления эффекта или при необходимости до 4 недель. Нельзя проводить лечение в течение более 4 недель. При необходимости продолжительного лечения следует постепенно уменьшить частоту нанесения или использовать менее активные препараты. После каждого нанесения препарата Дермовейт перед применением смягчающего средства необходимо обеспечить достаточное время для впитывания.\u003Cbr\u003EДля предупреждения обострений кожных заболеваний проводят короткие (прерывистые) курсы лечения препаратом Дермовейт.\u003Cbr\u003EВ особо резистентных случаях, особенно при наличии гиперкератоза, эффект крема для наружного применения Дермовейт может быть усилен с помощью наложения на ночь на область применения препарата окклюзионной повязки (полиэтиленовой пленки), что обычно сопровождается положительной динамикой симптомов. В дальнейшем достигнутый эффект удается поддерживать без применения окклюзионной повязки.\u003Cbr\u003EЕсли состояние усугубляется или не улучшается в течение 2-4 недель, следует пересмотреть диагноз и проводимое лечение.\u003Cbr\u003EМаксимальная еженедельная доза не должна превышать 50 г/нед.\u003Cbr\u003EАтопический дерматит (экзема)\u003Cbr\u003EЛечение препаратом Дермовейт следует постепенно отменять сразу же после достижения контроля над заболеванием, а лечение смягчающим средством должно быть продолжено в качестве поддерживающей терапии.\u003Cbr\u003EВнезапная отмена препарата Дермовейт может приводить к рецидиву ранее имевшихся дерматозов.\u003Cbr\u003EЭкзема (упорное течение)\u003Cbr\u003EПациенты с частыми рецидивами заболевания\u003Cbr\u003EВ случае острого заболевания, как только будет достигнут эффект от непрерывного курса лечения ГКС для наружного применения, может быть рассмотрена возможность его прерывистого применения (1 раз/сут, 2 раза в неделю, без окклюзионной повязки). Показано, что такое лечение эффективно снижает частоту развития рецидивов.\u003Cbr\u003EНанесение препарата должно быть продолжено на все ранее пораженные участки кожи или на известные области потенциального обострения. Такая схема применения должна сочетаться с рутинным ежедневным применением смягчающих средств. Следует проводить регулярную оценку состояния, а также пользы и риска от продолжения лечения.\u003Cbr\u003EОсобые группы пациентов\u003Cbr\u003EДети\u003Cbr\u003EУ детей более вероятно развитие местных и системных побочных эффектов при терапии ГКС для наружного применения и, как правило, им требуется проведение более коротких курсов лечения с использованием менее активных средств, чем у взрослых.\u003Cbr\u003EСледует соблюдать осторожность при использовании препарата Дермовейт у детей, чтобы обеспечить его нанесение в минимальном количестве, обеспечивающем терапевтический эффект.\u003Cbr\u003EПациенты пожилого возраста\u003Cbr\u003EКлинические исследования не выявили каких-либо различий в эффективности препарата у пожилых и более молодых пациентов. Большая распространенность сниженной функции печени или почек у пациентов пожилого возраста может приводить к замедлению выведения препарата в случае его системной абсорбции. Следовательно, он должен применяться у пожилых пациентов в минимальном количестве и в течение как можно более короткого периода, но при этом обеспечивая достижение необходимого клинического эффекта.\u003Cbr\u003EПациенты с нарушением функции почек и/или печени\u003Cbr\u003EВ случае системной абсорбции препарата (при нанесении на обширные поверхности кожи в течение продолжительного периода) его метаболизм и выведение могут замедляться, приводя к повышенному риску развития системной токсичности. Следовательно, он должен применяться у таких пациентов в минимальном количестве и в течение как можно более короткого периода, при этом обеспечивая достижение необходимого клинического эффекта."},{"name":"Побочные действия","value":"Нежелательные явления, представленные ниже, перечислены в зависимости от анатомо-физиологической классификации и частоты встречаемости. Частота встречаемости определяется следующим образом: очень часто (≥1/10), часто (≥1/100 и \u003C1/10), нечасто (≥1/1 000 и \u003C1/100), редко (≥1/10 000 и \u003C1/1 000), очень редко (\u003C1/10 000, включая отдельные случаи). Категории частоты были сформированы на основании клинических исследований препарата и пострегистрационного наблюдения.\u003Cbr\u003EИнфекционные и паразитарные заболевания: очень редко - инфекция, вызываемая условно-патогенными организмами.\u003Cbr\u003EСо стороны иммунной системы: очень редко - гиперчувствительность.\u003Cbr\u003EСо стороны эндокринной системы: очень редко - угнетение гипоталамо-гипофизарно-надпочечниковой системы. Признаки кушингоида (лунообразное лицо, ожирение по центральному типу), задержка прибавки массы тела и/или задержка роста у детей, остеопороз, глаукома, гипергликемия и/или глюкозурия, катаракта, гипертония, повышение массы тела или ожирение, снижение уровня эндогенного кортизола, алопеция, ломкость волос.\u003Cbr\u003EСо стороны кожи и подкожных тканей: часто - зуд, чувство жжения или болезненность; нечасто - местная атрофия кожи*, стрии*, телеангиэктазии*; очень редко - истончение*, морщинистость кожи, сухость кожи*, изменение пигментации*, гипертрихоз, усугубление симптомов заболевания, аллергический контактный дерматит, пустулезный псориаз, эритема, сыпь, крапивница.\u003Cbr\u003E* Кожные проявления вторичны по отношению к местным и/или системным эффектам угнетения гипоталамо-гипофизарно-надпочечниковой системы.\u003Cbr\u003EОбщие расстройства и нарушения вместе введения: очень редко - раздражение и/или болезненность в месте нанесения.\u003Cbr\u003EПри нанесении на большие поверхности в течение длительного периода времени (например, более 2 недель) у пациентов могут развиваться системные побочные эффекты: гастрит, изъязвление слизистой оболочки ЖКТ, повышение внутриглазного давления, симптомы гиперкортицизма."},{"name":"Фармакологическое действие","value":"ГКС для наружного применения. Предупреждает краевое скопление нейтрофилов, уменьшает воспалительную экссудацию и продукцию лимфокинов, тормозит миграцию макрофагов, снижает интенсивность процессов инфильтрации и грануляции, оказывает местный противовоспалительный, противозудный, противоаллергический и антиэкссудативный эффекты."},{"name":"Фармакологическая группа","value":"глюкокортикостероиды"},{"name":"Форма выпуска","value":"крем"},{"name":"Способ применения/введения","value":"наружный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-kozhi","categoryId":"15756517","navnodeId":"25025070","glfilters":["35947170:36763741"]}}},{"name":"Минимальный возраст применения","value":"от 1 года"},{"name":"Условия хранения","value":"Препарат следует хранить в недоступном для детей месте при температуре не выше 30°C. Срок годности - 2 года."},{"name":"Передозировка","value":"Симптомы: препарат Дермовейт при наружном применении может абсорбироваться в количествах, достаточных для того, чтобы вызвать развитие системных эффектов. Развитие острой передозировки маловероятно. Однако в случае хронической передозировки или неправильного применения препарата Дермовейт могут развиться симптомы гиперкортицизма.\u003Cbr\u003EЛечение: в случае передозировки препарата Дермовейт следует постепенно отменять препарат, снижая частоту нанесения или заменяя менее активным ГКС, под наблюдением врача ввиду риска возникновения надпочечниковой недостаточности.\u003Cbr\u003EДальнейшее лечение следует проводить с учетом клинической ситуации или в соответствии с рекомендациями токсикологических центров при их наличии."},{"name":"Применение при беременности и кормлении грудью","value":"Беременность\u003Cbr\u003E\nДанные о применении клобетазола у беременных женщин ограничены.\u003Cbr\u003E\nНаружное применение глюкокортикостероидов у беременных животных может вызывать нарушения развития плода. Значение этих данных для человека не было установлено.\u003Cbr\u003E\nПрименение клобетазола во время беременности возможно только в том случае, если ожидаемая польза для матери превосходит потенциальный риск для плода.\u003Cbr\u003E\nСледует применять минимальное количество препарата на протяжении минимального периода времени.\u003Cbr\u003E\nПериод грудного вскармливания\u003Cbr\u003E\nПрименение препарата в период грудного вскармливания противопоказано."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Исследований по изучению влияния клобетазола на способность к управлению транспортными средствами или работе с механизмами не проводилось. Исходя из профиля побочных реакций клобетазола для наружного применения, какого-либо неблагоприятного влияния на такие виды деятельности не ожидается."},{"name":"Особые указания","value":"Препарат Дермовейт следует применять с осторожностью у пациентов с наличием в анамнезе местной повышенной чувствительности к ГКС или к любому вспомогательному веществу, входящему в состав препарата. Местные реакции повышенной чувствительности могут иметь сходство с симптомами протекающего заболевания. У некоторых лиц в результате повышенной системной абсорбции ГКС для наружного применения могут возникать проявления гиперкортицизма (синдрома Иценко-Кушинга) и обратимое угнетение гипоталамо-гипофизарно-надпочечниковой системы, ведущее к развитию глюкокортикоидной недостаточности. Если наблюдается любое из вышеуказанного, следует отменить препарат, постепенно уменьшая частоту его нанесения, или заменить его менее активным ГКС. Внезапное прекращение лечения может привести к развитию глюкокортикостероидной недостаточности.\u003Cbr\u003EК факторам риска усиления системных эффектов относятся: активность ГКС и состав лекарственного препарата для наружного применения, продолжительность применения, нанесение препарата на обширные участки кожи, применение в закрытых областях кожи (т.е. в интертригинозных зонах или под окклюзионные повязки (пеленки и подгузники у младенцев могут играть роль окклюзионной повязки)), повышенная гидратация рогового слоя кожи, использование на областях с тонкой кожей, таких как лицо, нанесение на поврежденную кожу или при других состояниях, которые могут сопровождаться нарушением целостности кожного барьера. По сравнению со взрослыми у детей и младенцев может отмечаться больший процент абсорбции ГКС для наружного применения, в связи с чем данная категория пациентов более подвержена риску развития системных побочных эффектов. Это обусловлено тем, что дети имеют незрелый кожный барьер и большее значение отношения площади поверхности тела к массе тела по сравнению с взрослыми.\u003Cbr\u003EПрименение у детей\u003Cbr\u003EПо возможности следует избегать назлечения ГКС для наружного применения в течение продолжительного времени у детей младше 12 лет, т.к. длительное применение ГКС для наружного применения может вызывать угнетение функции надпочечников.\u003Cbr\u003EУ детей чаще, чем у взрослых возникают атрофические изменения кожи при наружном применении ГКС. В случае назначения клобетазола детям курс лечения должен ограничиваться несколькими днями, требуется наблюдение у врача не реже 1 раза в неделю.\u003Cbr\u003EПрименение при псориазе\u003Cbr\u003EВ некоторых случаях лечение псориаза ГКС для наружного применения может сопровождаться возобновлением симптомов заболевания, устойчивостью к препарату, развитием генерализованной пустулезной формы псориаза и местной или системной токсичностью из-за нарушения барьерной функции кожи, поэтому особенно важно внимательное наблюдение за пациентом.\u003Cbr\u003EСопутствующая инфекция\u003Cbr\u003EПри присоединении вторичной инфекции следует проводить соответствующую антибактериальную терапию. При любых признаках генерализации инфекции необходимо прекратить наружное применение ГКС и провести соответствующее лечение антибактериальными препаратами.\u003Cbr\u003EРиск развития инфекции при окклюзии\u003Cbr\u003EТеплые влажные условия, создаваемые при наложении окклюзионной повязки, способствуют возникновению бактериальной инфекции, поэтому следует обязательно тщательно очищать кожу перед наложением новой повязки.\u003Cbr\u003EХронические язвы голеней\u003Cbr\u003EГКС для наружного применения иногда используются для лечения дерматита вокруг хронических язв голеней. Однако такое применение может сопровождаться повышенной частотой возникновения местных реакций гиперчувствительности и повышенным риском развития местных инфекций.\u003Cbr\u003EНанесение на кожу лица\u003Cbr\u003EНанесение на кожу лица нежелательно, т.к. данная область более подвержена развитию атрофических изменений. В случае нанесения на кожу лица лечение следует ограничить несколькими днями.\u003Cbr\u003EНанесение на веки\u003Cbr\u003EПри нанесении крема на веки необходимо следить за тем, чтобы препарат не попал в глаза, потому что неоднократное воздействие крема может вызвать катаракту и глаукому."},{"name":"Взаимодействие","value":"Было показано, что одновременное применение препаратов, способных ингибировать изофермент CYP3A4 (например, ритонавира и итраконазола), угнетает метаболизм ГКС, приводя к повышению их системной экспозиции. Степень клинической значимости данного взаимодействия зависит от дозы и способа применения ГКС и активности ингибитора изофермента CYP3A4."},{"name":"Регистрационный номер","value":"П N015790/01"},{"name":"Дата государственной регистрации","value":"20.12.2018"},{"name":"Владелец регистрационного удостоверения","value":"GlaxoSmithKline, Inc.","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-kozhi","categoryId":"15756517","navnodeId":"25025070","glfilters":["34324371:35649313","7893318:17277767"]}}},{"name":"Изготовитель","value":"GlaxoSmithKline"},{"name":"Фасовщик","value":"GlaxoSmithKline"},{"name":"Страна-производитель","value":"Польша"},{"name":"Название препарата","value":"Дермовейт","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-kozhi","categoryId":"15756517","navnodeId":"25025070","glfilters":["17796364:17876066"]}}},{"name":"Срок годности","value":"24 мес."}]}},"fullSpecsGrouped":{"1419191742188049968":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"кожа"},{"name":"Назначение","value":"атопический дерматит, проблемная кожа, псориаз"},{"name":"Показания к применению","value":"Препарат Дермовейт является высокоактивным ГКС для наружного применения, который показан для применения у взрослых, лиц пожилого возраста и детей в возрасте старше 1 года для облегчения симптомов воспаления и кожного зуда при дерматозах, чувствительных к терапии ГКС.\u003Cbr\u003E— псориаз (исключая распространенный бляшечный псориаз);\u003Cbr\u003E— экзема (различные формы);\u003Cbr\u003E— красный плоский лишай;\u003Cbr\u003E— дискоидная красная волчанка;\u003Cbr\u003E— дерматозы, устойчивые к терапии менее активными ГКС для наружного применения."},{"name":"Противопоказания","value":"Повышенная чувствительность к клобетазолу или любому другому компоненту, входящему в состав препарата;\nнелеченые инфекции кожи;\nрозовые угри (розацеа);\nакне;\nпериоральный дерматит;\nкожный зуд в отсутствие воспаления;\nперианальный и генитальный зуд;\nдетский возраст до 1 года."},{"name":"Состав","value":"Действующее вещество: клобетазола пропионат – 0.05 г\u003Cbr\u003EВспомогательные вещества: глицерола моностеарат – 11 г, пропиленгликоля глицерил олеат (арлацель 165) – 1.5 мг, воск пчелиный заменитель 6621 – 1.25 г, цетостеариловый спирт – 8.4 г, пропиленгликоль – 47.5 г, хлорокрезол – 75 мг, натрия цитрат – 50 мг, лимонной кислоты моногидрат – 50 мг, вода очищенная – до 100 г\u003Cbr/\u003E"},{"name":"Действующее вещество","value":"Клобетазол"},{"name":"Способ применения и дозы","value":"Наружно.\u003Cbr\u003EНанесение крема особенно целесообразно на влажные или мокнущие поверхности.\u003Cbr\u003EКрем наносится тонким слоем в количестве, достаточном для покрытия всей пораженной области, 1-2 раза/сут, осторожно втирается. Длительность применения - до появления эффекта или при необходимости до 4 недель. Нельзя проводить лечение в течение более 4 недель. При необходимости продолжительного лечения следует постепенно уменьшить частоту нанесения или использовать менее активные препараты. После каждого нанесения препарата Дермовейт перед применением смягчающего средства необходимо обеспечить достаточное время для впитывания.\u003Cbr\u003EДля предупреждения обострений кожных заболеваний проводят короткие (прерывистые) курсы лечения препаратом Дермовейт.\u003Cbr\u003EВ особо резистентных случаях, особенно при наличии гиперкератоза, эффект крема для наружного применения Дермовейт может быть усилен с помощью наложения на ночь на область применения препарата окклюзионной повязки (полиэтиленовой пленки), что обычно сопровождается положительной динамикой симптомов. В дальнейшем достигнутый эффект удается поддерживать без применения окклюзионной повязки.\u003Cbr\u003EЕсли состояние усугубляется или не улучшается в течение 2-4 недель, следует пересмотреть диагноз и проводимое лечение.\u003Cbr\u003EМаксимальная еженедельная доза не должна превышать 50 г/нед.\u003Cbr\u003EАтопический дерматит (экзема)\u003Cbr\u003EЛечение препаратом Дермовейт следует постепенно отменять сразу же после достижения контроля над заболеванием, а лечение смягчающим средством должно быть продолжено в качестве поддерживающей терапии.\u003Cbr\u003EВнезапная отмена препарата Дермовейт может приводить к рецидиву ранее имевшихся дерматозов.\u003Cbr\u003EЭкзема (упорное течение)\u003Cbr\u003EПациенты с частыми рецидивами заболевания\u003Cbr\u003EВ случае острого заболевания, как только будет достигнут эффект от непрерывного курса лечения ГКС для наружного применения, может быть рассмотрена возможность его прерывистого применения (1 раз/сут, 2 раза в неделю, без окклюзионной повязки). Показано, что такое лечение эффективно снижает частоту развития рецидивов.\u003Cbr\u003EНанесение препарата должно быть продолжено на все ранее пораженные участки кожи или на известные области потенциального обострения. Такая схема применения должна сочетаться с рутинным ежедневным применением смягчающих средств. Следует проводить регулярную оценку состояния, а также пользы и риска от продолжения лечения.\u003Cbr\u003EОсобые группы пациентов\u003Cbr\u003EДети\u003Cbr\u003EУ детей более вероятно развитие местных и системных побочных эффектов при терапии ГКС для наружного применения и, как правило, им требуется проведение более коротких курсов лечения с использованием менее активных средств, чем у взрослых.\u003Cbr\u003EСледует соблюдать осторожность при использовании препарата Дермовейт у детей, чтобы обеспечить его нанесение в минимальном количестве, обеспечивающем терапевтический эффект.\u003Cbr\u003EПациенты пожилого возраста\u003Cbr\u003EКлинические исследования не выявили каких-либо различий в эффективности препарата у пожилых и более молодых пациентов. Большая распространенность сниженной функции печени или почек у пациентов пожилого возраста может приводить к замедлению выведения препарата в случае его системной абсорбции. Следовательно, он должен применяться у пожилых пациентов в минимальном количестве и в течение как можно более короткого периода, но при этом обеспечивая достижение необходимого клинического эффекта.\u003Cbr\u003EПациенты с нарушением функции почек и/или печени\u003Cbr\u003EВ случае системной абсорбции препарата (при нанесении на обширные поверхности кожи в течение продолжительного периода) его метаболизм и выведение могут замедляться, приводя к повышенному риску развития системной токсичности. Следовательно, он должен применяться у таких пациентов в минимальном количестве и в течение как можно более короткого периода, при этом обеспечивая достижение необходимого клинического эффекта."},{"name":"Побочные действия","value":"Нежелательные явления, представленные ниже, перечислены в зависимости от анатомо-физиологической классификации и частоты встречаемости. Частота встречаемости определяется следующим образом: очень часто (≥1/10), часто (≥1/100 и \u003C1/10), нечасто (≥1/1 000 и \u003C1/100), редко (≥1/10 000 и \u003C1/1 000), очень редко (\u003C1/10 000, включая отдельные случаи). Категории частоты были сформированы на основании клинических исследований препарата и пострегистрационного наблюдения.\u003Cbr\u003EИнфекционные и паразитарные заболевания: очень редко - инфекция, вызываемая условно-патогенными организмами.\u003Cbr\u003EСо стороны иммунной системы: очень редко - гиперчувствительность.\u003Cbr\u003EСо стороны эндокринной системы: очень редко - угнетение гипоталамо-гипофизарно-надпочечниковой системы. Признаки кушингоида (лунообразное лицо, ожирение по центральному типу), задержка прибавки массы тела и/или задержка роста у детей, остеопороз, глаукома, гипергликемия и/или глюкозурия, катаракта, гипертония, повышение массы тела или ожирение, снижение уровня эндогенного кортизола, алопеция, ломкость волос.\u003Cbr\u003EСо стороны кожи и подкожных тканей: часто - зуд, чувство жжения или болезненность; нечасто - местная атрофия кожи*, стрии*, телеангиэктазии*; очень редко - истончение*, морщинистость кожи, сухость кожи*, изменение пигментации*, гипертрихоз, усугубление симптомов заболевания, аллергический контактный дерматит, пустулезный псориаз, эритема, сыпь, крапивница.\u003Cbr\u003E* Кожные проявления вторичны по отношению к местным и/или системным эффектам угнетения гипоталамо-гипофизарно-надпочечниковой системы.\u003Cbr\u003EОбщие расстройства и нарушения вместе введения: очень редко - раздражение и/или болезненность в месте нанесения.\u003Cbr\u003EПри нанесении на большие поверхности в течение длительного периода времени (например, более 2 недель) у пациентов могут развиваться системные побочные эффекты: гастрит, изъязвление слизистой оболочки ЖКТ, повышение внутриглазного давления, симптомы гиперкортицизма."},{"name":"Фармакологическое действие","value":"ГКС для наружного применения. Предупреждает краевое скопление нейтрофилов, уменьшает воспалительную экссудацию и продукцию лимфокинов, тормозит миграцию макрофагов, снижает интенсивность процессов инфильтрации и грануляции, оказывает местный противовоспалительный, противозудный, противоаллергический и антиэкссудативный эффекты."},{"name":"Фармакологическая группа","value":"глюкокортикостероиды"},{"name":"Форма выпуска","value":"крем"},{"name":"Способ применения/введения","value":"наружный"},{"name":"Минимальный возраст применения","value":"от 1 года"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"Препарат следует хранить в недоступном для детей месте при температуре не выше 30°C. Срок годности - 2 года."},{"name":"Передозировка","value":"Симптомы: препарат Дермовейт при наружном применении может абсорбироваться в количествах, достаточных для того, чтобы вызвать развитие системных эффектов. Развитие острой передозировки маловероятно. Однако в случае хронической передозировки или неправильного применения препарата Дермовейт могут развиться симптомы гиперкортицизма.\u003Cbr\u003EЛечение: в случае передозировки препарата Дермовейт следует постепенно отменять препарат, снижая частоту нанесения или заменяя менее активным ГКС, под наблюдением врача ввиду риска возникновения надпочечниковой недостаточности.\u003Cbr\u003EДальнейшее лечение следует проводить с учетом клинической ситуации или в соответствии с рекомендациями токсикологических центров при их наличии."},{"name":"Применение при беременности и кормлении грудью","value":"Беременность\u003Cbr\u003E\nДанные о применении клобетазола у беременных женщин ограничены.\u003Cbr\u003E\nНаружное применение глюкокортикостероидов у беременных животных может вызывать нарушения развития плода. Значение этих данных для человека не было установлено.\u003Cbr\u003E\nПрименение клобетазола во время беременности возможно только в том случае, если ожидаемая польза для матери превосходит потенциальный риск для плода.\u003Cbr\u003E\nСледует применять минимальное количество препарата на протяжении минимального периода времени.\u003Cbr\u003E\nПериод грудного вскармливания\u003Cbr\u003E\nПрименение препарата в период грудного вскармливания противопоказано."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Исследований по изучению влияния клобетазола на способность к управлению транспортными средствами или работе с механизмами не проводилось. Исходя из профиля побочных реакций клобетазола для наружного применения, какого-либо неблагоприятного влияния на такие виды деятельности не ожидается."},{"name":"Особые указания","value":"Препарат Дермовейт следует применять с осторожностью у пациентов с наличием в анамнезе местной повышенной чувствительности к ГКС или к любому вспомогательному веществу, входящему в состав препарата. Местные реакции повышенной чувствительности могут иметь сходство с симптомами протекающего заболевания. У некоторых лиц в результате повышенной системной абсорбции ГКС для наружного применения могут возникать проявления гиперкортицизма (синдрома Иценко-Кушинга) и обратимое угнетение гипоталамо-гипофизарно-надпочечниковой системы, ведущее к развитию глюкокортикоидной недостаточности. Если наблюдается любое из вышеуказанного, следует отменить препарат, постепенно уменьшая частоту его нанесения, или заменить его менее активным ГКС. Внезапное прекращение лечения может привести к развитию глюкокортикостероидной недостаточности.\u003Cbr\u003EК факторам риска усиления системных эффектов относятся: активность ГКС и состав лекарственного препарата для наружного применения, продолжительность применения, нанесение препарата на обширные участки кожи, применение в закрытых областях кожи (т.е. в интертригинозных зонах или под окклюзионные повязки (пеленки и подгузники у младенцев могут играть роль окклюзионной повязки)), повышенная гидратация рогового слоя кожи, использование на областях с тонкой кожей, таких как лицо, нанесение на поврежденную кожу или при других состояниях, которые могут сопровождаться нарушением целостности кожного барьера. По сравнению со взрослыми у детей и младенцев может отмечаться больший процент абсорбции ГКС для наружного применения, в связи с чем данная категория пациентов более подвержена риску развития системных побочных эффектов. Это обусловлено тем, что дети имеют незрелый кожный барьер и большее значение отношения площади поверхности тела к массе тела по сравнению с взрослыми.\u003Cbr\u003EПрименение у детей\u003Cbr\u003EПо возможности следует избегать назлечения ГКС для наружного применения в течение продолжительного времени у детей младше 12 лет, т.к. длительное применение ГКС для наружного применения может вызывать угнетение функции надпочечников.\u003Cbr\u003EУ детей чаще, чем у взрослых возникают атрофические изменения кожи при наружном применении ГКС. В случае назначения клобетазола детям курс лечения должен ограничиваться несколькими днями, требуется наблюдение у врача не реже 1 раза в неделю.\u003Cbr\u003EПрименение при псориазе\u003Cbr\u003EВ некоторых случаях лечение псориаза ГКС для наружного применения может сопровождаться возобновлением симптомов заболевания, устойчивостью к препарату, развитием генерализованной пустулезной формы псориаза и местной или системной токсичностью из-за нарушения барьерной функции кожи, поэтому особенно важно внимательное наблюдение за пациентом.\u003Cbr\u003EСопутствующая инфекция\u003Cbr\u003EПри присоединении вторичной инфекции следует проводить соответствующую антибактериальную терапию. При любых признаках генерализации инфекции необходимо прекратить наружное применение ГКС и провести соответствующее лечение антибактериальными препаратами.\u003Cbr\u003EРиск развития инфекции при окклюзии\u003Cbr\u003EТеплые влажные условия, создаваемые при наложении окклюзионной повязки, способствуют возникновению бактериальной инфекции, поэтому следует обязательно тщательно очищать кожу перед наложением новой повязки.\u003Cbr\u003EХронические язвы голеней\u003Cbr\u003EГКС для наружного применения иногда используются для лечения дерматита вокруг хронических язв голеней. Однако такое применение может сопровождаться повышенной частотой возникновения местных реакций гиперчувствительности и повышенным риском развития местных инфекций.\u003Cbr\u003EНанесение на кожу лица\u003Cbr\u003EНанесение на кожу лица нежелательно, т.к. данная область более подвержена развитию атрофических изменений. В случае нанесения на кожу лица лечение следует ограничить несколькими днями.\u003Cbr\u003EНанесение на веки\u003Cbr\u003EПри нанесении крема на веки необходимо следить за тем, чтобы препарат не попал в глаза, потому что неоднократное воздействие крема может вызвать катаракту и глаукому."},{"name":"Взаимодействие","value":"Было показано, что одновременное применение препаратов, способных ингибировать изофермент CYP3A4 (например, ритонавира и итраконазола), угнетает метаболизм ГКС, приводя к повышению их системной экспозиции. Степень клинической значимости данного взаимодействия зависит от дозы и способа применения ГКС и активности ингибитора изофермента CYP3A4."},{"name":"Регистрационный номер","value":"П N015790/01"},{"name":"Дата государственной регистрации","value":"20.12.2018"},{"name":"Владелец регистрационного удостоверения","value":"GlaxoSmithKline, Inc."},{"name":"Изготовитель","value":"GlaxoSmithKline"},{"name":"Фасовщик","value":"GlaxoSmithKline"},{"name":"Страна-производитель","value":"Польша"},{"name":"Название препарата","value":"Дермовейт"},{"name":"Срок годности","value":"24 мес."}]}],"transitionId":"tr_11290608931717240059"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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  • Дайвобет мазь, 15 г
    –1 %
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    Дайвобет мазь, 15 г

    Рейтинг товара: 4.8 из 5
    на основе 57 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 1 436 ₽ вместо 1 451
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  • Дайвонекс мазь, 0.005%, 30 мл, 30 г
    –1 %
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    Дайвонекс мазь, 0.005%, 30 мл, 30 г

    Рейтинг товара: 4.9 из 5
    на основе 25 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 1 340 ₽ вместо 1 354
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  • Псоридонт крем противопсориазный, 50 мл, 50 г, 1 шт.
    –38 %
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    Псоридонт крем противопсориазный, 50 мл, 50 г, 1 шт.

    Рейтинг товара: 4 из 5
    на основе 3 оценки
    Цена 400 ₽ вместо 650
    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  • Дермазин крем, 1%, 50 г
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    Дермазин крем, 1%, 50 г

    Рейтинг товара: 4.9 из 5
    на основе 50 оценок
    Цена 402 ₽
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  • Пикладол крем противопсориазный, 30 мл, 100 г, 1 шт., 1 уп.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-oxbzx30r2il/toggleWishlist":{"skuId":"677836028","productId":1778172185,"offerId":"GRqRi6KW2Xezhq0wptOpvQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQqsbowseQvLl6EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYImYLzzwYQ/OmbwwIY7MW8BCDl2cEH","sign":"P4u6UfMkth++5k2Ka0ZRh5RRurLs7BP9RrYrTcRIgOQ="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-oxbzx30r2il/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Пикладол крем противопсориазный, 30 мл, 100 г, 1 шт., 1 уп.

    Рейтинг товара: 4.5 из 5
    на основе 4 оценки
    Цена 364 ₽
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  • Цинокап крем д/нар. прим., 0,2 %, 0.5 мл, 25 г
    –1 %
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    Цинокап крем д/нар. прим., 0,2 %, 0.5 мл, 25 г

    Рейтинг товара: 4.5 из 5
    на основе 66 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 557 ₽ вместо 563
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  • Псорилом крем д/тела, 75 мл
    ВАМ–47 %
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    Псорилом крем д/тела, 75 мл

    Рейтинг товара: 4.7 из 5
    на основе 37 оценок
    Цена 466 ₽ вместо 875
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  • Ксамиол гель д/нар. прим., 15 г
    –1 %
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    Ксамиол гель д/нар. прим., 15 г

    Рейтинг товара: 4.7 из 5
    на основе 54 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 1 424 ₽ вместо 1 438
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  • Лостерин крем, 75 мл, 102 г, 1 шт., 1 уп.
    –1 %
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    Лостерин крем, 75 мл, 102 г, 1 шт., 1 уп.

    Рейтинг товара: 5 из 5
    на основе 10 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 1 007 ₽ вместо 1 017
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  • Пантомеколь крем, 5 %., 25 г, 1 шт.
    –2 %
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    Пантомеколь крем, 5 %., 25 г, 1 шт.

    С картой  Пэй
    Цена с картой Яндекс Пэй 365 ₽ вместо 373
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Инструкция

Показания к применению

Препарат Дермовейт является высокоактивным ГКС для наружного применения, который показан для применения у взрослых, лиц пожилого возраста и детей в возрасте старше 1 года для облегчения симптомов воспаления и кожного зуда при дерматозах, чувствительных к терапии ГКС.
— псориаз (исключая распространенный бляшечный псориаз);
— экзема (различные формы);
— красный плоский лишай;
— дискоидная красная волчанка;
— дерматозы, устойчивые к терапии менее активными ГКС для наружного применения.

Противопоказания

Повышенная чувствительность к клобетазолу или любому другому компоненту, входящему в состав препарата; нелеченые инфекции кожи; розовые угри (розацеа); акне; периоральный дерматит; кожный зуд в отсутствие воспаления; перианальный и генитальный зуд; детский возраст до 1 года.

Способ применения и дозы

Наружно.
Нанесение крема особенно целесообразно на влажные или мокнущие поверхности.
Крем наносится тонким слоем в количестве, достаточном для покрытия всей пораженной области, 1-2 раза/сут, осторожно втирается. Длительность применения - до появления эффекта или при необходимости до 4 недель. Нельзя проводить лечение в течение более 4 недель. При необходимости продолжительного лечения следует постепенно уменьшить частоту нанесения или использовать менее активные препараты. После каждого нанесения препарата Дермовейт перед применением смягчающего средства необходимо обеспечить достаточное время для впитывания.
Для предупреждения обострений кожных заболеваний проводят короткие (прерывистые) курсы лечения препаратом Дермовейт.
В особо резистентных случаях, особенно при наличии гиперкератоза, эффект крема для наружного применения Дермовейт может быть усилен с помощью наложения на ночь на область применения препарата окклюзионной повязки (полиэтиленовой пленки), что обычно сопровождается положительной динамикой симптомов. В дальнейшем достигнутый эффект удается поддерживать без применения окклюзионной повязки.
Если состояние усугубляется или не улучшается в течение 2-4 недель, следует пересмотреть диагноз и проводимое лечение.
Максимальная еженедельная доза не должна превышать 50 г/нед.
Атопический дерматит (экзема)
Лечение препаратом Дермовейт следует постепенно отменять сразу же после достижения контроля над заболеванием, а лечение смягчающим средством должно быть продолжено в качестве поддерживающей терапии.
Внезапная отмена препарата Дермовейт может приводить к рецидиву ранее имевшихся дерматозов.
Экзема (упорное течение)
Пациенты с частыми рецидивами заболевания
В случае острого заболевания, как только будет достигнут эффект от непрерывного курса лечения ГКС для наружного применения, может быть рассмотрена возможность его прерывистого применения (1 раз/сут, 2 раза в неделю, без окклюзионной повязки). Показано, что такое лечение эффективно снижает частоту развития рецидивов.
Нанесение препарата должно быть продолжено на все ранее пораженные участки кожи или на известные области потенциального обострения. Такая схема применения должна сочетаться с рутинным ежедневным применением смягчающих средств. Следует проводить регулярную оценку состояния, а также пользы и риска от продолжения лечения.
Особые группы пациентов
Дети
У детей более вероятно развитие местных и системных побочных эффектов при терапии ГКС для наружного применения и, как правило, им требуется проведение более коротких курсов лечения с использованием менее активных средств, чем у взрослых.
Следует соблюдать осторожность при использовании препарата Дермовейт у детей, чтобы обеспечить его нанесение в минимальном количестве, обеспечивающем терапевтический эффект.
Пациенты пожилого возраста
Клинические исследования не выявили каких-либо различий в эффективности препарата у пожилых и более молодых пациентов. Большая распространенность сниженной функции печени или почек у пациентов пожилого возраста может приводить к замедлению выведения препарата в случае его системной абсорбции. Следовательно, он должен применяться у пожилых пациентов в минимальном количестве и в течение как можно более короткого периода, но при этом обеспечивая достижение необходимого клинического эффекта.
Пациенты с нарушением функции почек и/или печени
В случае системной абсорбции препарата (при нанесении на обширные поверхности кожи в течение продолжительного периода) его метаболизм и выведение могут замедляться, приводя к повышенному риску развития системной токсичности. Следовательно, он должен применяться у таких пациентов в минимальном количестве и в течение как можно более короткого периода, при этом обеспечивая достижение необходимого клинического эффекта.
Полная инструкция
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Дермовейт крем
Дермовейт крем, 0,05%, 25 мл, 25 г
4.9
(17)
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1 вопрос
Инструкция

837 ₽

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4.9
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У продавца:17 оценок·5 отзывов
У всех продавцов:112 оценок·36 отзывов
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user avatar
6 месяцев назад • Имя скрыто • Куплен на Маркете
Достоинства: Реально помогает от бляшек псориаза.
Комментарий: Месяц пользуюсь, пятна медленно, но верно начинают исчезать.
user avatar
Неделю назад • ирина м. • Куплен на Маркете
Достоинства: Помогает
user avatar
3 месяца назад • Сергей Андреевич • Куплен на Маркете
Достоинства: то что нужно
Недостатки: цена
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    Крем для лица и тела после загара MIXIT "BACK TO SUN" защитный, увлажняющий, с пантенолом и алоэ вера, 150 мл

    Цена 543 ₽ вместо 1 110
  • Vitamin D3, 10000 МЕ, 120 шт.
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    Vitamin D3, 10000 МЕ, 120 шт.

    Цена 1 210 ₽ вместо 2 455
  • Пластырь-повязка 10*8 см медицинская стерильная на рану и шов 20 штук, Fixplast с сорбционной подушечкой
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    Пластырь-повязка 10*8 см медицинская стерильная на рану и шов 20 штук, Fixplast с сорбционной подушечкой

    Цена 222 ₽ вместо 279
  • Кловейт мазь, 0,05%, 25 мл, 25 г
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    Кловейт мазь, 0,05%, 25 мл, 25 г

    Цена 565 ₽
  • Дайвобет мазь, 15 г
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    Дайвобет мазь, 15 г

    Цена 1 436 ₽ вместо 1 451
  • Салфетка спиртовая (этиловый спирт) 60*100 мм 100 шт.
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    Салфетка спиртовая (этиловый спирт) 60*100 мм 100 шт.

    Цена 208 ₽ вместо 288
  • Дайвонекс мазь, 0.005%, 30 мл, 30 г
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    Дайвонекс мазь, 0.005%, 30 мл, 30 г

    Цена 1 340 ₽ вместо 1 354
  • "Асептика" - Салфетки спиртовые антисептические, 6х10см, 100шт
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    "Асептика" - Салфетки спиртовые антисептические, 6х10см, 100шт

    Цена 210 ₽ вместо 250
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  • Вата стерильная хирургическая 100 г
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    Вата стерильная хирургическая 100 г

    Цена 173 ₽ вместо 198
  • Johnson's Baby, детская присыпка для тела, 200 гр.
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    Johnson's Baby, детская присыпка для тела, 200 гр.

    Цена 323 ₽ вместо 399
  • Дермазин крем, 1%, 50 г
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    Дермазин крем, 1%, 50 г

    Цена 402 ₽
  • Псоридонт крем противопсориазный, 50 мл, 50 г, 1 шт.
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    Псоридонт крем противопсориазный, 50 мл, 50 г, 1 шт.

    Цена 350 ₽ вместо 470
  • Цинокап крем д/нар. прим., 0,2 %, 0.5 мл, 25 г
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    Цинокап крем д/нар. прим., 0,2 %, 0.5 мл, 25 г

    Цена 557 ₽ вместо 563
  • Акваназаль Софт аэр., 150 мл, 120 г, 1 шт., 1 уп.
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    Акваназаль Софт аэр., 150 мл, 120 г, 1 шт., 1 уп.

    Цена 285 ₽ вместо 520
  • Псорилом крем д/тела, 75 мл
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    Псорилом крем д/тела, 75 мл

    Цена 466 ₽ вместо 875
  • Салфетка с нашатырем для стимуляции дыхания 3х6, 20 шт
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    Салфетка с нашатырем для стимуляции дыхания 3х6, 20 шт

    Цена 199 ₽ вместо 250
  • Бинт эластичный самофиксирующийся 5см/4.5м
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    Бинт эластичный самофиксирующийся 5см/4.5м

    Цена 144 ₽ вместо 290
  • Ксамиол гель д/нар. прим., 15 г
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    Ксамиол гель д/нар. прим., 15 г

    Цена 1 424 ₽ вместо 1 438
  • Лостерин крем, 75 мл, 102 г, 1 шт., 1 уп.
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    Лостерин крем, 75 мл, 102 г, 1 шт., 1 уп.

    Цена 1 007 ₽ вместо 1 017
  • Пикладол крем противопсориазный, 30 мл, 100 г, 1 шт., 1 уп.
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    Пикладол крем противопсориазный, 30 мл, 100 г, 1 шт., 1 уп.

    Цена 364 ₽
  • Реклама
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  • Дезиптол кожный антисептик 1 л
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    Дезиптол кожный антисептик 1 л

    Цена 512 ₽ вместо 640
  • Фитол-8 Псоризан-Fito крем д/тела, 90 мл, 75 г, 1 шт., 1 уп.
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    Фитол-8 Псоризан-Fito крем д/тела, 90 мл, 75 г, 1 шт., 1 уп.

    Цена 459 ₽ вместо 689
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