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Описание

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Эффезел гель д/нар. прим., 1 мг/г+25 мг/г, 30 мл, 30 г, 1 шт.

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4.9
(45)
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Коротко о товаре

Артикул Маркета
4509440216
Тип препарата
Назначение
Действующее вещество
Возраст
от 12 лет
Инструкция
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Продолжительность лечения должна устанавливаться врачом на основании клинического состояния пациента.\u003Cbr\u003EВ случае появлении признаков раздражения кожи рекомендуется применение некомедоногенных средств с увлажняющим действием, число аппликаций может быть сокращено (например, через день), лечение может быть временно приостановлено до исчезновения признаков раздражения или полностью прекращено."},{"name":"Побочные действия","value":"Частота побочных эффектов распределяется в следующем порядке: часто (в 1% - 10% случаев); нечасто (в 0,1% -1% случаев).\u003Cbr\u003EСо стороны кожи и подкожно-жировой клетчатки:\u003Cbr\u003EЧасто: сухость кожи, раздражительный контактный дерматит, жжение и раздражение кожи.Нечасто: зуд, солнечный ожог.\u003Cbr\u003EЧастота неизвестна (постмаркетинговые данные): аллергический контактный дерматит.\u003Cbr\u003EВ случае развития раздражения кожи его интенсивность обычно легкая или умеренная, с местными симптомами переносимости (покраснение, сухость, шелушение и жжение), которые достигают пика в течение первой недели лечения, а затем самопроизвольно уходят."},{"name":"Фармакологическое действие","value":"Эффезел содержит в своем составе два активных вещества с различными, однако взаимодополняющими, механизмами действия.\u003Cbr\u003EАдапален. Адапален является химически стабильным производным нафтойной кислоты с ретиноидоподобным действием. Адапален действует патогенетически при аспе vulgaris: является сильным модулятором процессов клеточной дифференцировки и кератинизации, а также обладает противовоспалительным действием. Механизм действия препарата основан на связывании адапалена со специфическими ядерными рецепторами ретиноевой кислоты. Современные данные позволяют предположить, что при местном применении адапален нормализует процесс дифференцировки эпителиальных клеток фолликулов, снижая таким образом образование микрокомедонов. In vitro адапален угнетает хемотаксический (направленный) и хемокинетический (произвольный) ответы полиморфноядерных лейкоцитов человека, а также угнетает метаболизм арахидоновой кислоты и образование медиаторов воспаления. По данным исследований in vitro адапален угнетает АР-1 факторы, а также экспрессию toll-подобных рецепторов-2. 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Обладает себостатическим действием, предупреждая чрезмерную выработку кожного сала, сопровождающую угревую сыпь."},{"name":"Фармакологическая группа","value":"средство лечения угревой сыпи"},{"name":"Форма выпуска","value":"гель"},{"name":"Способ применения/введения","value":"наружный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-kozhi","categoryId":"15756517","navnodeId":"25025070","glfilters":["35947170:36763741"]}}},{"name":"Минимальный возраст применения","value":"от 12 лет"},{"name":"Условия хранения","value":"При температуре не выше 25 °С Хранить в недоступном для детей месте!"},{"name":"Передозировка","value":"Эффезел следует наносить только один раз в день.\u003Cbr\u003EПри случайном проглатывании следует провести соответствующую симптоматическую терапию."},{"name":"Применение при беременности и кормлении грудью","value":"Беременность\u003Cbr\u003EДанных по местному применению комбинации адапалена и бензоила пероксида у беременных женщин не достаточно. Однако несколько имеющихся данных, собранных у пациенток, получавших препарат на ранних сроках беременности, не свидетельствуют о каком-либо его отрицательном влиянии.\u003Cbr\u003EИсследования комбинации адапалена и бензоила пероксида на животных, в которых препарат скармливался животным перорально, показали токсическое действие на репродуктивную систему при высокой системной экспозиции.\u003Cbr\u003EВследствие ограниченности имеющихся данных, а также вследствие возможного слабого проникновения адапалена через кожу, Эффезел не следует применять во время беременности. В случае наступления беременности лечение следует прекратить.\u003Cbr\u003EЛактация\u003Cbr\u003EИсследований проникновения препарата в молоко животных или человека после накожного нанесения геля Эффезел не проводилось. Поскольку системная экспозиция Эффезела у кормящих женщин незначительна, никакого влияния на находящихся на грудном вскармливании младенцев не ожидается.\u003Cbr\u003EЭффезел может применятся во время кормления грудью. Следует избегать контакта новорожденного с препаратом, нанесения препарата на грудь при использовании в период грудного вскармливания."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Гель Эффезел не оказывает влияния на способность к управлению транспортными средствами и работе с механизмами."},{"name":"Особые указания","value":"Не следует наносить гель Эффезел на поврежденную в результате травм (порезы или ссадины) или экзематозно измененную кожу.\u003Cbr\u003EИзбегать контакта с глазами, ротовой полостью, ноздрями и другими слизистыми оболочками. При попадании препарата в глаза немедленно промыть их теплой водой. Препарат содержит пропиленгликоль (Е1520), который может вызвать раздражение кожи. При подозрении на повышенную чувствительность к какому-либо из ингредиентов препарата применение Эффезеля следует прекратить.\u003Cbr\u003EСледует избегать чрезмерного воздействия солнечного света или УФ излучения.\u003Cbr\u003EСледует избегать контакта с какими-либо окрашенными материалами (включая волосы и окрашенные ткани), поскольку это может привести к изменению их цвета или обесцвечиванию."},{"name":"Взаимодействие","value":"Исследований взаимодействия с другими лекарственными средствами не проводилось.\u003Cbr\u003EНа основании имеющегося опыта применения адапалена и бензоила пероксида взаимодействия с другими лекарственными средствами не выявлены.\u003Cbr\u003EТем не менее, не следует одновременно применять другие ретиноиды или бензоила пероксид, либо препараты с подобным механизмом действия. Следует соблюдать осторожность при одновременном применении косметических средств с отшелушивающим, раздражающим или подсушивающим действием из-за возможного дополнительного раздражающего эффекта.\u003Cbr\u003EВсасывание адапалена через кожу низко, поэтому развитие взаимодействия с системными лекарственными средствами маловероятно.\u003Cbr\u003EПроникновение бензоила пероксида через кожу низко, он полностью метаболизируется до бензойной кислоты, которая быстро выводится из организма. В связи с этим развитие взаимодействия бензойной кислоты с системными препаратами является маловероятным."},{"name":"Регистрационный номер","value":"ЛП-000738"},{"name":"Дата государственной регистрации","value":"25.03.2022"},{"name":"Владелец регистрационного удостоверения","value":"Galderma","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-kozhi","categoryId":"15756517","navnodeId":"25025070","glfilters":["34324371:35649313","7893318:11906575"]}}},{"name":"Изготовитель","value":"Galderma"},{"name":"Фасовщик","value":"Galderma"},{"name":"Страна бренда","value":"Швейцария"},{"name":"Страна-производитель","value":"Франция"},{"name":"Название препарата","value":"Эффезел","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-kozhi","categoryId":"15756517","navnodeId":"25025070","glfilters":["17796364:17879626"]}}},{"name":"Срок годности","value":"24 мес."}]}},"fullSpecsGrouped":{"10093997913159348487":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"кожа"},{"name":"Назначение","value":"угревая болезнь"},{"name":"Показания к применению","value":"Местное лечение угревой сыпи с комедонами, папулами и пустулами."},{"name":"Противопоказания","value":"Повышенная чувствительность к действующим веществам или любому из компонентов препарата;\u003Cbr\u003E\nДетский возраст до 9 лет (безопасность и эффективность препарата не установлена).\u003Cbr\u003E\nС осторожностью:\u003Cbr\u003E\nБезопасность и эффективность препарата не исследовалась у детей младше 12 лет."},{"name":"Состав","value":"В 1 г геля содержится:\u003Cbr\u003EАктивные вещества: Адапален - 0,001 г Бензоила пероксид - 0,025 г\u003Cbr\u003EВспомогательные вещества: симульгель 600 РНА (сополимер акриламида и акрилоилдиметил таурата 35-40%, изогексадекан 20-25%, полисорбат 80 5-10%, сорбитан олеат 2,5%, вода до 100%) - 0,04 г, докузат натрия - 0,0005 г, динатрия эдетат - 0,001 г, глицерол - 0,04 г, полоксамер 124 - 0,002 г, пропиленгликоль - 0,04 г, вода очищенная - до 1 г."},{"name":"Действующее вещество","value":"Адапален+Бензоила пероксид"},{"name":"Способ применения и дозы","value":"Наружно.\u003Cbr\u003EНаносить тонкой пленкой с помощью кончиков пальцев на всю пораженную поверхность один раз в день вечером на чистую и сухую кожу, избегая попадания в глаза и на слизистую губ.\u003Cbr\u003EТерапевтический эффект развивается через 1-4 недели лечения. Продолжительность лечения должна устанавливаться врачом на основании клинического состояния пациента.\u003Cbr\u003EВ случае появлении признаков раздражения кожи рекомендуется применение некомедоногенных средств с увлажняющим действием, число аппликаций может быть сокращено (например, через день), лечение может быть временно приостановлено до исчезновения признаков раздражения или полностью прекращено."},{"name":"Побочные действия","value":"Частота побочных эффектов распределяется в следующем порядке: часто (в 1% - 10% случаев); нечасто (в 0,1% -1% случаев).\u003Cbr\u003EСо стороны кожи и подкожно-жировой клетчатки:\u003Cbr\u003EЧасто: сухость кожи, раздражительный контактный дерматит, жжение и раздражение кожи.Нечасто: зуд, солнечный ожог.\u003Cbr\u003EЧастота неизвестна (постмаркетинговые данные): аллергический контактный дерматит.\u003Cbr\u003EВ случае развития раздражения кожи его интенсивность обычно легкая или умеренная, с местными симптомами переносимости (покраснение, сухость, шелушение и жжение), которые достигают пика в течение первой недели лечения, а затем самопроизвольно уходят."},{"name":"Фармакологическое действие","value":"Эффезел содержит в своем составе два активных вещества с различными, однако взаимодополняющими, механизмами действия.\u003Cbr\u003EАдапален. Адапален является химически стабильным производным нафтойной кислоты с ретиноидоподобным действием. Адапален действует патогенетически при аспе vulgaris: является сильным модулятором процессов клеточной дифференцировки и кератинизации, а также обладает противовоспалительным действием. Механизм действия препарата основан на связывании адапалена со специфическими ядерными рецепторами ретиноевой кислоты. Современные данные позволяют предположить, что при местном применении адапален нормализует процесс дифференцировки эпителиальных клеток фолликулов, снижая таким образом образование микрокомедонов. In vitro адапален угнетает хемотаксический (направленный) и хемокинетический (произвольный) ответы полиморфноядерных лейкоцитов человека, а также угнетает метаболизм арахидоновой кислоты и образование медиаторов воспаления. По данным исследований in vitro адапален угнетает АР-1 факторы, а также экспрессию toll-подобных рецепторов-2. Таким образом, можно сказать, что под влиянием адапалена снижается клеточно-опосредованный воспалительный компонент угревой сыпи.\u003Cbr\u003EБензоила пероксид. Бензоила пероксид оказывает противомикробное действие, в частности, в отношении Propionibacterium acnes, присутствующих в сально-волосяном фолликуле при угревой сыпи. Оказывает отшелушивающее и кератолитическое действие. Обладает себостатическим действием, предупреждая чрезмерную выработку кожного сала, сопровождающую угревую сыпь."},{"name":"Фармакологическая группа","value":"средство лечения угревой сыпи"},{"name":"Форма выпуска","value":"гель"},{"name":"Способ применения/введения","value":"наружный"},{"name":"Минимальный возраст применения","value":"от 12 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"При температуре не выше 25 °С Хранить в недоступном для детей месте!"},{"name":"Передозировка","value":"Эффезел следует наносить только один раз в день.\u003Cbr\u003EПри случайном проглатывании следует провести соответствующую симптоматическую терапию."},{"name":"Применение при беременности и кормлении грудью","value":"Беременность\u003Cbr\u003EДанных по местному применению комбинации адапалена и бензоила пероксида у беременных женщин не достаточно. Однако несколько имеющихся данных, собранных у пациенток, получавших препарат на ранних сроках беременности, не свидетельствуют о каком-либо его отрицательном влиянии.\u003Cbr\u003EИсследования комбинации адапалена и бензоила пероксида на животных, в которых препарат скармливался животным перорально, показали токсическое действие на репродуктивную систему при высокой системной экспозиции.\u003Cbr\u003EВследствие ограниченности имеющихся данных, а также вследствие возможного слабого проникновения адапалена через кожу, Эффезел не следует применять во время беременности. В случае наступления беременности лечение следует прекратить.\u003Cbr\u003EЛактация\u003Cbr\u003EИсследований проникновения препарата в молоко животных или человека после накожного нанесения геля Эффезел не проводилось. Поскольку системная экспозиция Эффезела у кормящих женщин незначительна, никакого влияния на находящихся на грудном вскармливании младенцев не ожидается.\u003Cbr\u003EЭффезел может применятся во время кормления грудью. Следует избегать контакта новорожденного с препаратом, нанесения препарата на грудь при использовании в период грудного вскармливания."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Гель Эффезел не оказывает влияния на способность к управлению транспортными средствами и работе с механизмами."},{"name":"Особые указания","value":"Не следует наносить гель Эффезел на поврежденную в результате травм (порезы или ссадины) или экзематозно измененную кожу.\u003Cbr\u003EИзбегать контакта с глазами, ротовой полостью, ноздрями и другими слизистыми оболочками. При попадании препарата в глаза немедленно промыть их теплой водой. Препарат содержит пропиленгликоль (Е1520), который может вызвать раздражение кожи. При подозрении на повышенную чувствительность к какому-либо из ингредиентов препарата применение Эффезеля следует прекратить.\u003Cbr\u003EСледует избегать чрезмерного воздействия солнечного света или УФ излучения.\u003Cbr\u003EСледует избегать контакта с какими-либо окрашенными материалами (включая волосы и окрашенные ткани), поскольку это может привести к изменению их цвета или обесцвечиванию."},{"name":"Взаимодействие","value":"Исследований взаимодействия с другими лекарственными средствами не проводилось.\u003Cbr\u003EНа основании имеющегося опыта применения адапалена и бензоила пероксида взаимодействия с другими лекарственными средствами не выявлены.\u003Cbr\u003EТем не менее, не следует одновременно применять другие ретиноиды или бензоила пероксид, либо препараты с подобным механизмом действия. Следует соблюдать осторожность при одновременном применении косметических средств с отшелушивающим, раздражающим или подсушивающим действием из-за возможного дополнительного раздражающего эффекта.\u003Cbr\u003EВсасывание адапалена через кожу низко, поэтому развитие взаимодействия с системными лекарственными средствами маловероятно.\u003Cbr\u003EПроникновение бензоила пероксида через кожу низко, он полностью метаболизируется до бензойной кислоты, которая быстро выводится из организма. В связи с этим развитие взаимодействия бензойной кислоты с системными препаратами является маловероятным."},{"name":"Регистрационный номер","value":"ЛП-000738"},{"name":"Дата государственной регистрации","value":"25.03.2022"},{"name":"Владелец регистрационного удостоверения","value":"Galderma"},{"name":"Изготовитель","value":"Galderma"},{"name":"Фасовщик","value":"Galderma"},{"name":"Страна бренда","value":"Швейцария"},{"name":"Страна-производитель","value":"Франция"},{"name":"Название препарата","value":"Эффезел"},{"name":"Срок годности","value":"24 мес."}]}],"transitionId":"tr_8383496048366573858"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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Ещё может подойти

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Инструкция

Показания к применению

Местное лечение угревой сыпи с комедонами, папулами и пустулами.

Противопоказания

Повышенная чувствительность к действующим веществам или любому из компонентов препарата;
Детский возраст до 9 лет (безопасность и эффективность препарата не установлена).
С осторожностью:
Безопасность и эффективность препарата не исследовалась у детей младше 12 лет.

Способ применения и дозы

Наружно.
Наносить тонкой пленкой с помощью кончиков пальцев на всю пораженную поверхность один раз в день вечером на чистую и сухую кожу, избегая попадания в глаза и на слизистую губ.
Терапевтический эффект развивается через 1-4 недели лечения. Продолжительность лечения должна устанавливаться врачом на основании клинического состояния пациента.
В случае появлении признаков раздражения кожи рекомендуется применение некомедоногенных средств с увлажняющим действием, число аппликаций может быть сокращено (например, через день), лечение может быть временно приостановлено до исчезновения признаков раздражения или полностью прекращено.
Полная инструкция
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Эффезел гель д/нар. прим.
Эффезел гель д/нар. прим., 1 мг/г+25 мг/г, 30 мл, 30 г, 1 шт.
4.9
(45)
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8 вопросов
Инструкция

2 078 ₽

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4.9
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У продавца:45 оценок·6 отзывов
У всех продавцов:576 оценок·116 отзывов
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user avatar
Месяц назад • Имя скрыто • Куплен на Маркете
Достоинства: Действительно помогает!
Недостатки: Может быть ожог при неправильном использовании
Комментарий: Дерматолог-косметолог говорила, чтобы во время лечения от акне я купила этот гель. Пользоваться надо аккуратно, чтобы не было ожога, точечно. Подсушивает за ночь, результат действительно быстрый (но возможно это работает в коллаборации с Сотретом)
user avatar
5 месяцев назад • Алена Ефремкина • Куплен на Маркете
Достоинства: Отличное средство
Недостатки: нет
Комментарий: Принимала по рекомендации дерматолога. После полугода применения состояние кожи значительно улучшилось. Рекомендую
user avatar
3 недели назад • Надежда • Куплен на Маркете
Комментарий: Много чем пользовались, данный препарат реально помог
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    Цена 1 190 ₽ вместо 2 455
  • Базирон АС гель д/нар. прим., 2,5 %, 40 мл, 40 г
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    Базирон АС гель д/нар. прим., 2,5 %, 40 мл, 40 г

    Цена 1 312 ₽ вместо 1 325
  • Азелик гель д/нар. прим., 15%, 30 мл, 30 г
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    Азелик гель д/нар. прим., 15%, 30 мл, 30 г

    Цена 992 ₽ вместо 1 002
  • Zinc Picolinate капс., 50 мг, 55 г, 60 шт.
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    Zinc Picolinate капс., 50 мг, 55 г, 60 шт.

    Цена 747 ₽ вместо 1 500
  • Клензит-C гель д/нар. прим., 15 г
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    Клензит-C гель д/нар. прим., 15 г

    Цена 1 008 ₽ вместо 1 018
  • Omega-3 капс., 1000 мг, 100 мл, 30 шт.
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    Omega-3 капс., 1000 мг, 100 мл, 30 шт.

    Цена 500 ₽ вместо 690
  • Дифферин гель, 0,1%, 30 г
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    Дифферин гель, 0,1%, 30 г

    Цена 1 340 ₽ вместо 1 354
  • Реклама
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  • ЛимфоТранзит концентрат напитка фл., 100 мл
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    ЛимфоТранзит концентрат напитка фл., 100 мл

    Цена 332 ₽ вместо 390
  • Solgar Zinc Picolinate таб., 170 г, 100 шт.
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    Solgar Zinc Picolinate таб., 170 г, 100 шт.

    Цена 1 342 ₽ вместо 1 356
  • Крем для лица и тела после загара MIXIT "BACK TO SUN" защитный, увлажняющий, с пантенолом и алоэ вера, 150 мл
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    Крем для лица и тела после загара MIXIT "BACK TO SUN" защитный, увлажняющий, с пантенолом и алоэ вера, 150 мл

    Цена 482 ₽ вместо 1 110
  • Клиндовит гель д/нар. прим., 1%, 30 г
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    Клиндовит гель д/нар. прим., 1%, 30 г

    Цена 496 ₽ вместо 501
  • Johnson's Baby, детская присыпка для тела, 200 гр.
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    Johnson's Baby, детская присыпка для тела, 200 гр.

    Цена 323 ₽ вместо 399
  • Жидкий пластырь Fixplast c пантенолом, 60 мл
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    Жидкий пластырь Fixplast c пантенолом, 60 мл

    Цена 333 ₽ вместо 399
  • Клензит гель д/нар. прим., 15 г
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    Клензит гель д/нар. прим., 15 г

    Цена 752 ₽ вместо 760
  • Пластырь-повязка 10*8 см медицинская стерильная на рану и шов 20 штук, Fixplast с сорбционной подушечкой
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    Пластырь-повязка 10*8 см медицинская стерильная на рану и шов 20 штук, Fixplast с сорбционной подушечкой

    Цена 222 ₽ вместо 279
  • Зеркалин р-р д/нар. прим. фл., 10 мг/мл, 30 мл
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    Зеркалин р-р д/нар. прим. фл., 10 мг/мл, 30 мл

    Цена 611 ₽ вместо 747
  • Салфетка спиртовая (этиловый спирт) 60*100 мм 100 шт.
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    Салфетка спиртовая (этиловый спирт) 60*100 мм 100 шт.

    Цена 208 ₽ вместо 288
  • Перфэктоин крем, 30 мл, 30 г, 1 шт., 1 уп.
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    Перфэктоин крем, 30 мл, 30 г, 1 шт., 1 уп.

    Цена 669 ₽ вместо 676
  • "Асептика" - Салфетки спиртовые антисептические, 6х10см, 100шт
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    "Асептика" - Салфетки спиртовые антисептические, 6х10см, 100шт

    Цена 210 ₽ вместо 250
  • Реклама
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  • Зеркалин Интенсив гель д/нар. прим., 50 мг+10 мг/г, 30 мл, 25 г
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    Зеркалин Интенсив гель д/нар. прим., 50 мг+10 мг/г, 30 мл, 25 г

    Цена 970 ₽
  • БиоГая Пробиотик капли детск. фл., 5 мл, 1 уп.
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    БиоГая Пробиотик капли детск. фл., 5 мл, 1 уп.

    Цена 2 025 ₽ вместо 3 500
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