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Описание

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Финастерид-OBL таб. п/о плен., 5 мг, 90 шт.

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4.8
(23)
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Количество штук в упаковке, шт.: 90

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Коротко о товаре

Артикул Маркета
4410742019
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
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5 мг;\u003Cbr\u003Eвспомогательные вещества: лактозы моногидрат, кальция гидрофосфата дигидрат, целлюлоза микрокристаллическая, кроскармеллоза натрия, натрия додецилсульфат, гипролоза (гидроксипропилцеллюлоза), магния стеарат;\u003Cbr\u003Eвспомогательные вещества для оболочки: гипромеллоза (гидроксипропилметилцеллюлоза), пропиленгликоль, титана диоксид, краситель азорубин."},{"name":"Действующее вещество","value":"Финастерид","transition":{"type":"catalog","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["27144131:28708452"]}}},{"name":"Способ применения и дозы","value":"Внутрь, независимо от приема пищи.\u003Cbr\u003EРекомендуемая доза - 1 таблетка (5 мг) 1 раз в сутки.\u003Cbr\u003EПрепарат Финастерид-OBL можно принимать в виде монотерапии, а также в комбинации с альфа-адреноблокатором доксазозином.\u003Cbr\u003EПродолжительность терапии до оценки ее эффективности должна быть не менее 6 месяцев.\u003Cbr\u003EРиск развития острой задержки мочи и оперативного вмешательства на предстательной железе уменьшается после 4 месяцев терапии финастеридом.\u003Cbr\u003EОсобые группы пациентов\u003Cbr\u003EПациенты пожилого возраста\u003Cbr\u003EКоррекция доз не требуется, хотя фармакокинетические исследования указывают на то, что выведение финастерида у пациентов старше 70 лет несколько снижается.\u003Cbr\u003EПациенты с нарушением функции почек\u003Cbr\u003EУ пациентов с различными стадиями почечной недостаточности (при снижении КК до 9\u003Cbr\u003Eмл/мин) коррекции доз не требуется, поскольку специальные продемонстрировали каких-либо изменений фармакокинетического профиля финастерида.\u003Cbr\u003EПациенты с печеночной недостаточностью\u003Cbr\u003EФармакокинетика финастерида у пациентов с печеночной недостаточностью не изучалась. Следует соблюдать осторожность при применении препарата Финастерид-OBL у таких пациентов.\u003Cbr\u003EДети\u003Cbr\u003EУ детей и подростков до 18 лет\u003Cbr\u003EПрепарат Финастерид-OBL не показан у детей и подростков в возрасте до 18 лет.\u003Cbr\u003EБезопасность и эффективность финастерида у пациентов в возрасте до 18 лет не установлены."},{"name":"Побочные действия","value":"Наиболее частые нежелательные реакции на фоне терапии финастеридом - импотенция и снижение либидо. Эти нежелательные реакции возникают в начале лечения и исчезают у большинства пациентов при продолжении терапии. Кроме того, в клинических исследованиях и с момента регистрации финастерида были зарегистрированы случаи рака грудной железы у мужчин.\u003Cbr\u003EВ 7-летнем плацебо-контролируемом исследовании, в которое было включено 18882 здоровых мужчин, по результатам проведенной пункционной биопсии (у 9 060 мужчин) рак предстательной железы был выявлен у 18,4 % пациентов, получавших финастерид, и у 24,4 % пациентов, получавших плацебо. У 280 мужчин (6,4 %) в группе пациентов, принимавших финастерид, и 237 мужчин (5,1 %) в группе плацебо был выявлен рак предстательной железы, который оценивался по результатам пункционной биопсии в 7-10 баллов по шкале Глисона. Дополнительный анализ позволил предложить, что увеличение частоты рака высокой степени злокачественности, наблюдаемое в группе пациентов, принимавших финастерид, может объясняться диагностическими погрешностями, связанными с влиянием препарата на объем предстательной железы. Приблизительно в 98 % всех диагностированных случаев рака опухоль была классифицирована в момент постановки диагноза как интракапсулярная (стадия Т1 и Т2). Клиническая значимость результатов, касающихся рака предстательной железы 7-10 баллов по шкале Глисона, в данном исследовании неизвестна.\u003Cbr\u003EВ другом исследовании профиль безопасности и переносимости терапии при комбинированном лечении финастеридом в дозе 5 мг в сутки и доксазозином 4 мг или 8 мг в сутки был сравним с безопасностью и переносимостью каждого из указанных препаратов в отдельности.\u003Cbr\u003EВ ходе данного 4-6 летнего плацебо-контролируемого исследования с использованием активного препарата в качестве контроля, проводимого с участием 3047 мужчин, зафиксировано 4 случая рака грудной железы у мужчин, принимавших финастерид и ни одного случая у мужчин, не принимавших финастерид.\u003Cbr\u003EВ ходе 4-летнего плацебо-контролируемого исследования, проводимого с участием 3040 мужчин, зафиксировано 2 случая рака грудной железы у мужчин, получавших плацебо, и ни одного случая у мужчин, принимавших финастерид. В ходе 7-летнего плацебо-контролируемого исследования, проводимого с участием 18882 мужчин, зафиксирован 1 случай рака грудной железы у мужчины, принимавшего финастерид, железы у мужчины, принимавшего финастерид, и 1 случай рака грудной получавшего плацебо.\u003Cbr\u003EЛабораторные показатели\u003Cbr\u003EПри оценке лабораторных показателей ПСА следует принимать во концентрации у пациентов, принимающих финастерид.\u003Cbr\u003EДругих различий в значении стандартных лабораторных показателей между группами пациентов, получавших финастерид и плацебо, не наблюдалось."},{"name":"Фармакологическое действие","value":"Финастерид - синтетическое 4-азастероидное соединение, является специфическим ингибитором 5-альфа редуктазы II типа - внутриклеточного фермента, который превращает тестостерон в более активный андроген - дигидротестостерон (ДГТ). При доброкачественной гиперплазии предстательной железы (ДГПЖ) ее увеличение зависит от превращения тестостерона в ДГТ в предстательной железе. Финастерид высокоэффективно снижает концентрацию ДГТ как в крови, так и в ткани предстательной железы. Подавление образования ДГТ сопровождается уменьшением размеров предстательной железы, увеличением максимальной скорости тока мочи и снижением выраженности симптомов, связанных с гиперплазией предстательной железы.\u003Cbr\u003EФинастерид не обладает сродством к рецептору андрогенов.\u003Cbr\u003EПрепарат не оказывает значимого влияния на липидный профиль (т. е. общий холестерин, липопротеины низкой плотности (ЛПНП), липопротеины высокой плотности (ЛПВП) и триглицериды) и минеральную плотность костной ткани. Финастерид не оказывает влияния на концентрацию в крови кортизола, эстрадиола, пролактина, тиреотропного гормона и тироксина в сравнении с плацебо.\u003Cbr\u003EОднократный прием финастерида в дозе 5 мг приводит к быстрому снижению концентрации ДГТ в сыворотке крови с достижением максимального эффекта через 8 ч. Несмотря на то, что концентрация финастерида в плазме крови подвергается колебаниям на протяжении 24 ч, концентрация ДГТ остается постоянной. Это означает, что концентрация финастерида в плазме крови напрямую не связана с концентрацией ДГТ в плазме крови.\u003Cbr\u003EУ пациентов с ДГПЖ, которым финастерид в дозе 5 мг в сутки назначался в течение 4 лет, наблюдалось снижение концентрации ДГТ в крови примерно на 70 %, которое ассоциировалось с уменьшением объема предстательной железы приблизительно на 20 %. Кроме этого, приблизительно на 50 % снижалась концентрация антигена (ПСА) по сравнению с его исходной концентрацией, что п] роста эпителиальных клеток предстательной железы. Снижение концентрации ДГТ и уменьшение выраженности гиперплазии предстательной железы, сопровождающееся снижением концентрации ПСА, сохранялось в исследованиях концентрация тестостерона в крови увеличивалось приблизительно на 10-20 %, оставаясь в пределах физиологических значений.\u003Cbr\u003EПри применении финастерида в течение 7-10 дней у пациентов, простатэктомию, произошло снижение концентрации ДГТ в ткани предстательной железы приблизительно на 80 % и увеличение концентрации тестостерона железы в 10 раз по сравнению с концентрацией до начала лечения.\u003Cbr\u003EУстановлено, что длительное (более 4 лет) применение финастерида у пациентов с ДГПЖ и умеренно выраженными или значительно выраженными симптомами заболевания снижало риск всех урологических осложнений (хирургические вмешательства, резекция предстательной железы или простатэктомия; острая задержка мочи, требующая катетеризации) на 51 % и сопровождалось выраженным и стойким уменьшением объем предстательной железы, а также стойким увеличением максимальной скорости тока мочи и улучшением симптоматики.\u003Cbr\u003EУ пациентов, принимавших финастерид в течение 3-х месяцев, объем предстательной железы, который уменьшался приблизительно на 20 %, возвращался к прежнему значению уже через 3 месяца после прекращения лечения.\u003Cbr\u003EТаким образом, лечение финастеридом способствует уменьшению размеров увеличенной предстательной железы, повышает скорость тока мочи и уменьшает симптомы, связанные с ДГПЖ."},{"name":"Фармакологическая группа","value":"5-альфа редуктазы ингибитор"},{"name":"Форма выпуска","value":"таблетки, покрытые пленочной оболочкой"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["35947170:36763744"]}}},{"name":"Пол","value":"для мужчин","transition":{"type":"catalog","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["14805991:14805992"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"При температуре не выше 25 °C.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы\u003Cbr\u003EСуществуют данные, что у пациентов, получавших финастерид в дозе до 400 мг однократно, а также в дозе до 80 мг в сутки на протяжении 3-х месяцев, не отмечалось возникновения каких-либо симптомов передозировки.\u003Cbr\u003EЛечение\u003Cbr\u003EВ случае передозировки финастерида специального лечения не требуется."},{"name":"Применение при беременности и кормлении грудью","value":"По зарегистрированному показанию препарат Финастерид-OBL не предназначен для применения у женщин."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"О неблагоприятном влиянии препарата на способность управлять транспортными средствами и работать с механизмами не сообщалось."},{"name":"Особые указания","value":"Пациенты с большим остаточным объемом мочи и/или существенно сниженным оттоком мочи должны находиться под регулярным наблюдением врала для своевременного выявления обструктивной уропатии.\u003Cbr\u003EВлияние на концентрацию ПСА и диагностику рака предстательной железы\u003Cbr\u003EДо настоящего времени не доказаны клинические преимущества применения финастерида у пациентов с раком предстательной железы. В контролируемых клинических исследованиях у пациентов с ДГПЖ и повышенной концентрацией ПСА проводился мониторинг концентрации ПСА и результатов исследований биопсии предстательной железы.\u003Cbr\u003EРезультаты исследований показали, что финастерид не оказывал влияния на частоту диагностирования рака предстательной железы и, в целом, не обнаружено достоверных различий частоты рака предстательной железы у пациентов финастеридом и плацебо.\u003Cbr\u003EПеред началом лечения и периодически в процессе терапии финастеридом рекомендуется проводить ректальное обследование и предстательной железы. Определение выявления рака предстательной железы, нг/мл говорит о необходимости дальнейшего обследования пациента и проведения биопсии.\u003Cbr\u003EПри определении концентрации ПСА в пределах 4-10 нг/мл необходимо дальнейшее обследование пациента. Концентрация ПСА у мужчин с раком предстательной железы и без данного заболевания может совпадать в значительной степени, поэтому у мужчин с ДГПЖ нормальные значения ПСА не позволяют исключить рак предстательной железы, независимо от лечения финастеридом. Исходная концентрация ПСА ниже 4 нг/мл, также не исключает рак предстательной железы.\u003Cbr\u003EФинастерид вызывает уменьшение концентрации сывороточного ПСА приблизительно на 50 % у пациентов с ДГПЖ, даже при наличии рака предстательной железы. Данный факт необходимо принимать во внимание при оценке содержания ПСА у пациентов с ДГПЖ, получающих финастерид, так как снижение концентрации ПСА не исключает наличия сопутствующего рака предстательной железы. Данное снижение возможно предвидеть при любом диапазоне значений концентрации ПСА, хотя оно может отличаться у конкретных пациентов. Анализ значений ПСА у более чем 3000 пациентов в 4-летнем двойном слепом плацебо-контролируемом исследовании подтвердил, что у принимавших финастерид в течение 6 месяцев и более, значение ПСА должны быть удвоены для из сопоставления с нормальными значениями данного показателя у пациентов, не получающих лечения препаратом. Эта коррекция сохраняет чувствительность и специфичность анализа ПСА и возможность выявления рака предстательной железы.\u003Cbr\u003EЛюбое сохраняющееся увеличение концентрации ПСА у пациентов, получающих лечение финастеридом, требует тщательного обследования для выяснения Причины, которая может заключаться в несоблюдении режима приема финастерида.\u003Cbr\u003EФинастерид существенно не снижает процент свободного ПСА (отношение свободного ПСА к общему). Данный показатель остается постоянным даже под влиянием приема препарата. Если для диагностики рака предстательной железы используется процент свободного ПСА, коррекция значений данного показателя необязательна.\u003Cbr\u003EВлияние на лабораторные показатели\u003Cbr\u003EКонцентрация ПСА\u003Cbr\u003EКонцентрация ПСА в плазме крови коррелирует с возрастом пациента и объемом предстательной железы, а объем предстательной железы, в свою очередь, зависит от возраста пациента. При определении концентрации ПСА следует учитывать, что данный показатель снижается у пациентов, принимающих финастерид. У большинства пациентов быстрое снижение концентрации ПСА наблюдается в первые месяцы терапии, после чего происходит стабилизации на новом уровне, который обычно составляет приблизительно половину значения, измеренного до начала терапии. В связи с этим, у пациентов, принимающих финастерид в течение 6-и и более месяцев, следует удваивать значение концентрации ПСА для сопоставления ее с нормальными показателями у мужчин, не принимающих препарат.\u003Cbr\u003EКонтакт с финастеридом связан с риском тератогенного эффекта для плода мужского пола\u003Cbr\u003EБеременные женщины, а также женщины фертильного возраста должны избегать контакта с измельченными или утратившими целостность таблетками финастерида из-за возможности абсорбции действующего вещества, обладающего потенциально высоким риском развития тератогенных эффектов для плода мужского пола.\u003Cbr\u003EРак грудной железы у мужчин\u003Cbr\u003EБыли получены сообщения о случаях рака грудной железы у финастерид в дозе 5 мг, во время клинических исследований и в пострегистрационный период. Врачи должны проинструктировать своих пациентов немедленно сообщать о любых изменениях в грудной железе, таких как припухлость, боль, увеличение грудных желез или выделение из соска.\u003Cbr\u003EИзменения настроения и депрессия\u003Cbr\u003EИзменения настроения, включая подавленное настроение, депрессию и, реже, суицидальные намерения наблюдались у пациентов, принимавших финастерид в дозе 5 мг. Необходимо мониторировать психические симптомы у пациентов, и в случае их появления, пациент должен обратиться к врачу за консультацией.\u003Cbr\u003EПрепарат содержит в составе краситель азорубин, который может вызывать аллергические реакции. Данный препарат содержит 1,2 мг натрия на 1 таблетку. Необходимо учитывать пациентам, находящимся на диете с ограничением поступления натрия.\u003Cbr\u003EС осторожностью:\u003Cbr\u003EУ пациентов с большим объемом остаточной мочи и/или существенно сниженным оттоком мочи, пожилых пациентов и пациентов с печеночной недостаточностью."},{"name":"Взаимодействие","value":"Клинически значимых взаимодействий финастерида с другими лекарственными средствами не выявлено.\u003Cbr\u003EФинастерид, по-видимому, не оказывает значимого влияния на систему цитохрома Р450 и метаболизм лекарственных средств, связанных с данной системой. Не было выявлено клинически значимых взаимодействий при комбинированном применении финастерида с пропранололом, дигоксином, глибенкламидом, варфарином, теофиллином и феназоном. Несмотря на отсутствие специальных исследований лекарственного взаимодействия, в клинических исследованиях финастерид применялся совместна с ингибиторами ангиотензинпревращающего фермента, парацетамолом, ацетилсалициловой кислоты, альфа-адреноблокаторами, бета-адреноблокаторами, блокаторами «медленных» кальциевых каналов, нитратами в различных лекарственных формах, диуретиками, блокаторами Н2-гистаминовых рецепторов, гиполипидемическими средствами - ингибиторами ГМГ-КоА- редуктазы, нестероидными противовоспалительными препаратами (НПВП), производными хинолона и бензодиазепина без каких-либо клинически значимых неблагоприятных взаимодействий."},{"name":"Регистрационный номер","value":"ЛП-№(000502)-(РГ-RU)"},{"name":"Дата государственной регистрации","value":"20.01.2023"},{"name":"Владелец регистрационного удостоверения","value":"Алиум","transition":{"type":"catalog","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["34324371:35649313","7893318:17728945"]}}},{"name":"Изготовитель","value":"Алиум"},{"name":"Фасовщик","value":"Алиум"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Срок годности","value":"1 г."}]}},"fullSpecsGrouped":{"10653167481886386549":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"предстательная железа"},{"name":"Назначение","value":"для улучшения и поддержания функции предстательной железы, доброкачественная гиперплазия предстательной железы"},{"name":"Показания к применению","value":"Препарат Финастерид-OBL показан только взрослым мужчинам от 18 лет.\u003Cbr\u003EЛечение и контроль доброкачественной гиперплазии предстательной железы (ДГПЖ), профилактика урологических осложнений с целью:\u003Cbr\u003Eснижения риска острой задержки мочи;\u003Cbr\u003Eснижения риска необходимости проведения хирургических вмешательств, в том числе трансуретральной резекции предстательной железы и простатэктомии.\u003Cbr\u003EЛечение с целью уменьшения размеров увеличенной предстательной железы, улучшения тока мочи и уменьшения выраженности симптомов, связанных с ДГПЖ.\u003Cbr\u003EВ сочетании с альфа-адреноблокатором доксазозином для снижения риска прогрессирования симптомов, связанных с ДГПЖ."},{"name":"Противопоказания","value":"Гиперчувствительность к финастериду и/или к любому из вспомогательных веществ в составе препарата.\u003Cbr\u003EВозраст до 18 лет.\u003Cbr\u003EРедко встречающаяся наследственная непереносимость галактозы, дефицит лактазы лопарей или глюкозо-галактозная мальабсорбция.\u003Cbr\u003EПо зарегистрированному показанию препарат Финастерид-OBL не показан для применения у женщин, детей и подростков до 18 лет."},{"name":"Состав","value":"1 таблетка препарата содержит:\u003Cbr\u003Eдействующее вещество: финастерид - 5 мг;\u003Cbr\u003Eвспомогательные вещества: лактозы моногидрат, кальция гидрофосфата дигидрат, целлюлоза микрокристаллическая, кроскармеллоза натрия, натрия додецилсульфат, гипролоза (гидроксипропилцеллюлоза), магния стеарат;\u003Cbr\u003Eвспомогательные вещества для оболочки: гипромеллоза (гидроксипропилметилцеллюлоза), пропиленгликоль, титана диоксид, краситель азорубин."},{"name":"Действующее вещество","value":"Финастерид"},{"name":"Способ применения и дозы","value":"Внутрь, независимо от приема пищи.\u003Cbr\u003EРекомендуемая доза - 1 таблетка (5 мг) 1 раз в сутки.\u003Cbr\u003EПрепарат Финастерид-OBL можно принимать в виде монотерапии, а также в комбинации с альфа-адреноблокатором доксазозином.\u003Cbr\u003EПродолжительность терапии до оценки ее эффективности должна быть не менее 6 месяцев.\u003Cbr\u003EРиск развития острой задержки мочи и оперативного вмешательства на предстательной железе уменьшается после 4 месяцев терапии финастеридом.\u003Cbr\u003EОсобые группы пациентов\u003Cbr\u003EПациенты пожилого возраста\u003Cbr\u003EКоррекция доз не требуется, хотя фармакокинетические исследования указывают на то, что выведение финастерида у пациентов старше 70 лет несколько снижается.\u003Cbr\u003EПациенты с нарушением функции почек\u003Cbr\u003EУ пациентов с различными стадиями почечной недостаточности (при снижении КК до 9\u003Cbr\u003Eмл/мин) коррекции доз не требуется, поскольку специальные продемонстрировали каких-либо изменений фармакокинетического профиля финастерида.\u003Cbr\u003EПациенты с печеночной недостаточностью\u003Cbr\u003EФармакокинетика финастерида у пациентов с печеночной недостаточностью не изучалась. Следует соблюдать осторожность при применении препарата Финастерид-OBL у таких пациентов.\u003Cbr\u003EДети\u003Cbr\u003EУ детей и подростков до 18 лет\u003Cbr\u003EПрепарат Финастерид-OBL не показан у детей и подростков в возрасте до 18 лет.\u003Cbr\u003EБезопасность и эффективность финастерида у пациентов в возрасте до 18 лет не установлены."},{"name":"Побочные действия","value":"Наиболее частые нежелательные реакции на фоне терапии финастеридом - импотенция и снижение либидо. Эти нежелательные реакции возникают в начале лечения и исчезают у большинства пациентов при продолжении терапии. Кроме того, в клинических исследованиях и с момента регистрации финастерида были зарегистрированы случаи рака грудной железы у мужчин.\u003Cbr\u003EВ 7-летнем плацебо-контролируемом исследовании, в которое было включено 18882 здоровых мужчин, по результатам проведенной пункционной биопсии (у 9 060 мужчин) рак предстательной железы был выявлен у 18,4 % пациентов, получавших финастерид, и у 24,4 % пациентов, получавших плацебо. У 280 мужчин (6,4 %) в группе пациентов, принимавших финастерид, и 237 мужчин (5,1 %) в группе плацебо был выявлен рак предстательной железы, который оценивался по результатам пункционной биопсии в 7-10 баллов по шкале Глисона. Дополнительный анализ позволил предложить, что увеличение частоты рака высокой степени злокачественности, наблюдаемое в группе пациентов, принимавших финастерид, может объясняться диагностическими погрешностями, связанными с влиянием препарата на объем предстательной железы. Приблизительно в 98 % всех диагностированных случаев рака опухоль была классифицирована в момент постановки диагноза как интракапсулярная (стадия Т1 и Т2). Клиническая значимость результатов, касающихся рака предстательной железы 7-10 баллов по шкале Глисона, в данном исследовании неизвестна.\u003Cbr\u003EВ другом исследовании профиль безопасности и переносимости терапии при комбинированном лечении финастеридом в дозе 5 мг в сутки и доксазозином 4 мг или 8 мг в сутки был сравним с безопасностью и переносимостью каждого из указанных препаратов в отдельности.\u003Cbr\u003EВ ходе данного 4-6 летнего плацебо-контролируемого исследования с использованием активного препарата в качестве контроля, проводимого с участием 3047 мужчин, зафиксировано 4 случая рака грудной железы у мужчин, принимавших финастерид и ни одного случая у мужчин, не принимавших финастерид.\u003Cbr\u003EВ ходе 4-летнего плацебо-контролируемого исследования, проводимого с участием 3040 мужчин, зафиксировано 2 случая рака грудной железы у мужчин, получавших плацебо, и ни одного случая у мужчин, принимавших финастерид. В ходе 7-летнего плацебо-контролируемого исследования, проводимого с участием 18882 мужчин, зафиксирован 1 случай рака грудной железы у мужчины, принимавшего финастерид, железы у мужчины, принимавшего финастерид, и 1 случай рака грудной получавшего плацебо.\u003Cbr\u003EЛабораторные показатели\u003Cbr\u003EПри оценке лабораторных показателей ПСА следует принимать во концентрации у пациентов, принимающих финастерид.\u003Cbr\u003EДругих различий в значении стандартных лабораторных показателей между группами пациентов, получавших финастерид и плацебо, не наблюдалось."},{"name":"Фармакологическое действие","value":"Финастерид - синтетическое 4-азастероидное соединение, является специфическим ингибитором 5-альфа редуктазы II типа - внутриклеточного фермента, который превращает тестостерон в более активный андроген - дигидротестостерон (ДГТ). При доброкачественной гиперплазии предстательной железы (ДГПЖ) ее увеличение зависит от превращения тестостерона в ДГТ в предстательной железе. Финастерид высокоэффективно снижает концентрацию ДГТ как в крови, так и в ткани предстательной железы. Подавление образования ДГТ сопровождается уменьшением размеров предстательной железы, увеличением максимальной скорости тока мочи и снижением выраженности симптомов, связанных с гиперплазией предстательной железы.\u003Cbr\u003EФинастерид не обладает сродством к рецептору андрогенов.\u003Cbr\u003EПрепарат не оказывает значимого влияния на липидный профиль (т. е. общий холестерин, липопротеины низкой плотности (ЛПНП), липопротеины высокой плотности (ЛПВП) и триглицериды) и минеральную плотность костной ткани. Финастерид не оказывает влияния на концентрацию в крови кортизола, эстрадиола, пролактина, тиреотропного гормона и тироксина в сравнении с плацебо.\u003Cbr\u003EОднократный прием финастерида в дозе 5 мг приводит к быстрому снижению концентрации ДГТ в сыворотке крови с достижением максимального эффекта через 8 ч. Несмотря на то, что концентрация финастерида в плазме крови подвергается колебаниям на протяжении 24 ч, концентрация ДГТ остается постоянной. Это означает, что концентрация финастерида в плазме крови напрямую не связана с концентрацией ДГТ в плазме крови.\u003Cbr\u003EУ пациентов с ДГПЖ, которым финастерид в дозе 5 мг в сутки назначался в течение 4 лет, наблюдалось снижение концентрации ДГТ в крови примерно на 70 %, которое ассоциировалось с уменьшением объема предстательной железы приблизительно на 20 %. Кроме этого, приблизительно на 50 % снижалась концентрация антигена (ПСА) по сравнению с его исходной концентрацией, что п] роста эпителиальных клеток предстательной железы. Снижение концентрации ДГТ и уменьшение выраженности гиперплазии предстательной железы, сопровождающееся снижением концентрации ПСА, сохранялось в исследованиях концентрация тестостерона в крови увеличивалось приблизительно на 10-20 %, оставаясь в пределах физиологических значений.\u003Cbr\u003EПри применении финастерида в течение 7-10 дней у пациентов, простатэктомию, произошло снижение концентрации ДГТ в ткани предстательной железы приблизительно на 80 % и увеличение концентрации тестостерона железы в 10 раз по сравнению с концентрацией до начала лечения.\u003Cbr\u003EУстановлено, что длительное (более 4 лет) применение финастерида у пациентов с ДГПЖ и умеренно выраженными или значительно выраженными симптомами заболевания снижало риск всех урологических осложнений (хирургические вмешательства, резекция предстательной железы или простатэктомия; острая задержка мочи, требующая катетеризации) на 51 % и сопровождалось выраженным и стойким уменьшением объем предстательной железы, а также стойким увеличением максимальной скорости тока мочи и улучшением симптоматики.\u003Cbr\u003EУ пациентов, принимавших финастерид в течение 3-х месяцев, объем предстательной железы, который уменьшался приблизительно на 20 %, возвращался к прежнему значению уже через 3 месяца после прекращения лечения.\u003Cbr\u003EТаким образом, лечение финастеридом способствует уменьшению размеров увеличенной предстательной железы, повышает скорость тока мочи и уменьшает симптомы, связанные с ДГПЖ."},{"name":"Фармакологическая группа","value":"5-альфа редуктазы ингибитор"},{"name":"Форма выпуска","value":"таблетки, покрытые пленочной оболочкой"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Пол","value":"для мужчин"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"При температуре не выше 25 °C.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы\u003Cbr\u003EСуществуют данные, что у пациентов, получавших финастерид в дозе до 400 мг однократно, а также в дозе до 80 мг в сутки на протяжении 3-х месяцев, не отмечалось возникновения каких-либо симптомов передозировки.\u003Cbr\u003EЛечение\u003Cbr\u003EВ случае передозировки финастерида специального лечения не требуется."},{"name":"Применение при беременности и кормлении грудью","value":"По зарегистрированному показанию препарат Финастерид-OBL не предназначен для применения у женщин."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"О неблагоприятном влиянии препарата на способность управлять транспортными средствами и работать с механизмами не сообщалось."},{"name":"Особые указания","value":"Пациенты с большим остаточным объемом мочи и/или существенно сниженным оттоком мочи должны находиться под регулярным наблюдением врала для своевременного выявления обструктивной уропатии.\u003Cbr\u003EВлияние на концентрацию ПСА и диагностику рака предстательной железы\u003Cbr\u003EДо настоящего времени не доказаны клинические преимущества применения финастерида у пациентов с раком предстательной железы. В контролируемых клинических исследованиях у пациентов с ДГПЖ и повышенной концентрацией ПСА проводился мониторинг концентрации ПСА и результатов исследований биопсии предстательной железы.\u003Cbr\u003EРезультаты исследований показали, что финастерид не оказывал влияния на частоту диагностирования рака предстательной железы и, в целом, не обнаружено достоверных различий частоты рака предстательной железы у пациентов финастеридом и плацебо.\u003Cbr\u003EПеред началом лечения и периодически в процессе терапии финастеридом рекомендуется проводить ректальное обследование и предстательной железы. Определение выявления рака предстательной железы, нг/мл говорит о необходимости дальнейшего обследования пациента и проведения биопсии.\u003Cbr\u003EПри определении концентрации ПСА в пределах 4-10 нг/мл необходимо дальнейшее обследование пациента. Концентрация ПСА у мужчин с раком предстательной железы и без данного заболевания может совпадать в значительной степени, поэтому у мужчин с ДГПЖ нормальные значения ПСА не позволяют исключить рак предстательной железы, независимо от лечения финастеридом. Исходная концентрация ПСА ниже 4 нг/мл, также не исключает рак предстательной железы.\u003Cbr\u003EФинастерид вызывает уменьшение концентрации сывороточного ПСА приблизительно на 50 % у пациентов с ДГПЖ, даже при наличии рака предстательной железы. Данный факт необходимо принимать во внимание при оценке содержания ПСА у пациентов с ДГПЖ, получающих финастерид, так как снижение концентрации ПСА не исключает наличия сопутствующего рака предстательной железы. Данное снижение возможно предвидеть при любом диапазоне значений концентрации ПСА, хотя оно может отличаться у конкретных пациентов. Анализ значений ПСА у более чем 3000 пациентов в 4-летнем двойном слепом плацебо-контролируемом исследовании подтвердил, что у принимавших финастерид в течение 6 месяцев и более, значение ПСА должны быть удвоены для из сопоставления с нормальными значениями данного показателя у пациентов, не получающих лечения препаратом. Эта коррекция сохраняет чувствительность и специфичность анализа ПСА и возможность выявления рака предстательной железы.\u003Cbr\u003EЛюбое сохраняющееся увеличение концентрации ПСА у пациентов, получающих лечение финастеридом, требует тщательного обследования для выяснения Причины, которая может заключаться в несоблюдении режима приема финастерида.\u003Cbr\u003EФинастерид существенно не снижает процент свободного ПСА (отношение свободного ПСА к общему). Данный показатель остается постоянным даже под влиянием приема препарата. Если для диагностики рака предстательной железы используется процент свободного ПСА, коррекция значений данного показателя необязательна.\u003Cbr\u003EВлияние на лабораторные показатели\u003Cbr\u003EКонцентрация ПСА\u003Cbr\u003EКонцентрация ПСА в плазме крови коррелирует с возрастом пациента и объемом предстательной железы, а объем предстательной железы, в свою очередь, зависит от возраста пациента. При определении концентрации ПСА следует учитывать, что данный показатель снижается у пациентов, принимающих финастерид. У большинства пациентов быстрое снижение концентрации ПСА наблюдается в первые месяцы терапии, после чего происходит стабилизации на новом уровне, который обычно составляет приблизительно половину значения, измеренного до начала терапии. В связи с этим, у пациентов, принимающих финастерид в течение 6-и и более месяцев, следует удваивать значение концентрации ПСА для сопоставления ее с нормальными показателями у мужчин, не принимающих препарат.\u003Cbr\u003EКонтакт с финастеридом связан с риском тератогенного эффекта для плода мужского пола\u003Cbr\u003EБеременные женщины, а также женщины фертильного возраста должны избегать контакта с измельченными или утратившими целостность таблетками финастерида из-за возможности абсорбции действующего вещества, обладающего потенциально высоким риском развития тератогенных эффектов для плода мужского пола.\u003Cbr\u003EРак грудной железы у мужчин\u003Cbr\u003EБыли получены сообщения о случаях рака грудной железы у финастерид в дозе 5 мг, во время клинических исследований и в пострегистрационный период. Врачи должны проинструктировать своих пациентов немедленно сообщать о любых изменениях в грудной железе, таких как припухлость, боль, увеличение грудных желез или выделение из соска.\u003Cbr\u003EИзменения настроения и депрессия\u003Cbr\u003EИзменения настроения, включая подавленное настроение, депрессию и, реже, суицидальные намерения наблюдались у пациентов, принимавших финастерид в дозе 5 мг. Необходимо мониторировать психические симптомы у пациентов, и в случае их появления, пациент должен обратиться к врачу за консультацией.\u003Cbr\u003EПрепарат содержит в составе краситель азорубин, который может вызывать аллергические реакции. Данный препарат содержит 1,2 мг натрия на 1 таблетку. Необходимо учитывать пациентам, находящимся на диете с ограничением поступления натрия.\u003Cbr\u003EС осторожностью:\u003Cbr\u003EУ пациентов с большим объемом остаточной мочи и/или существенно сниженным оттоком мочи, пожилых пациентов и пациентов с печеночной недостаточностью."},{"name":"Взаимодействие","value":"Клинически значимых взаимодействий финастерида с другими лекарственными средствами не выявлено.\u003Cbr\u003EФинастерид, по-видимому, не оказывает значимого влияния на систему цитохрома Р450 и метаболизм лекарственных средств, связанных с данной системой. Не было выявлено клинически значимых взаимодействий при комбинированном применении финастерида с пропранололом, дигоксином, глибенкламидом, варфарином, теофиллином и феназоном. Несмотря на отсутствие специальных исследований лекарственного взаимодействия, в клинических исследованиях финастерид применялся совместна с ингибиторами ангиотензинпревращающего фермента, парацетамолом, ацетилсалициловой кислоты, альфа-адреноблокаторами, бета-адреноблокаторами, блокаторами «медленных» кальциевых каналов, нитратами в различных лекарственных формах, диуретиками, блокаторами Н2-гистаминовых рецепторов, гиполипидемическими средствами - ингибиторами ГМГ-КоА- редуктазы, нестероидными противовоспалительными препаратами (НПВП), производными хинолона и бензодиазепина без каких-либо клинически значимых неблагоприятных взаимодействий."},{"name":"Регистрационный номер","value":"ЛП-№(000502)-(РГ-RU)"},{"name":"Дата государственной регистрации","value":"20.01.2023"},{"name":"Владелец регистрационного удостоверения","value":"Алиум"},{"name":"Изготовитель","value":"Алиум"},{"name":"Фасовщик","value":"Алиум"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Срок годности","value":"1 г."}]}],"transitionId":"tr_9016952455696899434"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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  • Финастерид-Тева таб. п/о плен., 5 мг, 90 шт.
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    Финастерид-Тева таб. п/о плен., 5 мг, 90 шт.

    Рейтинг товара: 4.7 из 5
    на основе 6 оценок
    Цена 972 ₽
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  • Финаст таб. п/о плен., 5 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-48kbd7cor3k/toggleWishlist":{"skuId":"228089929","productId":1778175603,"offerId":"T60YLfKDtSVOI-HfzqP6jg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQsf/Rss/u9MJ3EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI85zzzwYQycDhbBjAotUHIO7cwQc=","sign":"yGObIF9KDMMcWFAl+2Gj45Xwl8Rz6Psw5yhB1Lb5m60="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-48kbd7cor3k/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Финаст таб. п/о плен., 5 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 2 оценки
    Цена 374 ₽
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  • Силденафил-СЗ таб. п/о плен., 25 мг, 20 шт.
    –19 %
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    Силденафил-СЗ таб. п/о плен., 25 мг, 20 шт.

    Рейтинг товара: 4.7 из 5
    на основе 897 оценок
    Цена 216 ₽ вместо 266
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  • Тадалафил-СЗ таб. п/о плен., 20 мг, 4 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-330gmy1s8st/toggleWishlist":{"skuId":"662545162","productId":1430912592,"offerId":"PgowZnQ4D5BoXTzG0AZsrA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQsf/Rss/u9MJ3EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYI0PynqgUQisb2uwIYrt7QByDu3MEH","sign":"1N/dsCyIc3ddue/smKGFImUWamlwxw85JiLNIn9fue4="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-330gmy1s8st/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Тадалафил-СЗ таб. п/о плен., 20 мг, 4 шт.

    Рейтинг товара: 4.6 из 5
    на основе 220 оценок
    Цена 258 ₽
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  • Алфупрост МР таб. пролонг. высвоб., 10 мг, 30 шт.
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    Алфупрост МР таб. пролонг. высвоб., 10 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 9 оценок
    Цена 313 ₽
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  • Профлосин капс. кш/раств. пролонг. действ., 0.4 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-m3kj4zm57t/toggleWishlist":{"skuId":"228064684","productId":1430912453,"offerId":"bmF4SgwlMFX9L1HSOD5k4g","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQsf/Rss/u9MJ3EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIxfunqgUQrPvfbBinqtkHIO7cwQc=","sign":"+KnDAqMr8T1LJf1WWn5ush9LGixvifNqbvuA48ggP4s="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-m3kj4zm57t/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Профлосин капс. кш/раств. пролонг. действ., 0.4 мг, 30 шт.

    Рейтинг товара: 4.8 из 5
    на основе 19 оценок
    Цена 431 ₽
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  • Пенестер таб. п/о плен., 5 мг, 30 шт.
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    Пенестер таб. п/о плен., 5 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 4 оценки
    Цена 530 ₽
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  • Тамсулозин ретард таб. таб. пролонг. действ., 0.4 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ijfc6zirs8/toggleWishlist":{"skuId":"186882559","productId":1778175991,"offerId":"Gv_0gQKAgYEr8_LVzdsReg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQsf/Rss/u9MJ3EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI95/zzwYQ/7OOWRjr3NAHIO7cwQc=","sign":"JS8JOPMJixwV2vnS/c0SyyWM9K+cqCztpOoU5X3v7TU="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ijfc6zirs8/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Тамсулозин ретард таб. таб. пролонг. действ., 0.4 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 687 ₽
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  • Дутастерид-Тева капс., 0.5 мг, 30 шт.
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    Дутастерид-Тева капс., 0.5 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 4 оценки
    Цена 1 799 ₽
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  • Дутастерид Канон капс., 0.5 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-c4bvkt12zj/toggleWishlist":{"skuId":"101649528114","productId":1736611074,"offerId":"S1qN2PQH9Za8Dfn_AR57Jw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQsf/Rss/u9MJ3EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIgqqKvAYQsuqi1voCGM7C2Qcg7tzBBw==","sign":"Hcg/vNgjIiKbCxyztJCF26GncZe0myGfJGMSzj8j3Aw="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-c4bvkt12zj/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Дутастерид Канон капс., 0.5 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 2 оценки
    Цена 1 168 ₽
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  • Дапоксетин-СЗ таб. п/о плен., 30 мг, 30 шт.
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    Дапоксетин-СЗ таб. п/о плен., 30 мг, 30 шт.

    Рейтинг товара: 4.3 из 5
    на основе 62 оценки
    Цена 715 ₽
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  • Сонирид ДУО набор таб. №30 и капс. №30, 0.4 мг, 60 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-qk1uss7h6e/toggleWishlist":{"skuId":"186888027","productId":1778175996,"offerId":"erlFyYWa9g0SqxD8Dm27Yw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQsf/Rss/u9MJ3EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI/J/zzwYQ296OWRj+1bYIIO7cwQc=","sign":"hsj/J2xfGyBRuvoNjp9pAVJoCauXrIDPhCLm8pqKIDs="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-qk1uss7h6e/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Сонирид ДУО набор таб. №30 и капс. №30, 0.4 мг, 60 шт.

    Рейтинг товара: 4.3 из 5
    на основе 3 оценки
    Цена 1 449 ₽
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Инструкция

Показания к применению

Препарат Финастерид-OBL показан только взрослым мужчинам от 18 лет.
Лечение и контроль доброкачественной гиперплазии предстательной железы (ДГПЖ), профилактика урологических осложнений с целью:
снижения риска острой задержки мочи;
снижения риска необходимости проведения хирургических вмешательств, в том числе трансуретральной резекции предстательной железы и простатэктомии.
Лечение с целью уменьшения размеров увеличенной предстательной железы, улучшения тока мочи и уменьшения выраженности симптомов, связанных с ДГПЖ.
В сочетании с альфа-адреноблокатором доксазозином для снижения риска прогрессирования симптомов, связанных с ДГПЖ.

Противопоказания

Гиперчувствительность к финастериду и/или к любому из вспомогательных веществ в составе препарата.
Возраст до 18 лет.
Редко встречающаяся наследственная непереносимость галактозы, дефицит лактазы лопарей или глюкозо-галактозная мальабсорбция.
По зарегистрированному показанию препарат Финастерид-OBL не показан для применения у женщин, детей и подростков до 18 лет.

Способ применения и дозы

Внутрь, независимо от приема пищи.
Рекомендуемая доза - 1 таблетка (5 мг) 1 раз в сутки.
Препарат Финастерид-OBL можно принимать в виде монотерапии, а также в комбинации с альфа-адреноблокатором доксазозином.
Продолжительность терапии до оценки ее эффективности должна быть не менее 6 месяцев.
Риск развития острой задержки мочи и оперативного вмешательства на предстательной железе уменьшается после 4 месяцев терапии финастеридом.
Особые группы пациентов
Пациенты пожилого возраста
Коррекция доз не требуется, хотя фармакокинетические исследования указывают на то, что выведение финастерида у пациентов старше 70 лет несколько снижается.
Пациенты с нарушением функции почек
У пациентов с различными стадиями почечной недостаточности (при снижении КК до 9
мл/мин) коррекции доз не требуется, поскольку специальные продемонстрировали каких-либо изменений фармакокинетического профиля финастерида.
Пациенты с печеночной недостаточностью
Фармакокинетика финастерида у пациентов с печеночной недостаточностью не изучалась. Следует соблюдать осторожность при применении препарата Финастерид-OBL у таких пациентов.
Дети
У детей и подростков до 18 лет
Препарат Финастерид-OBL не показан у детей и подростков в возрасте до 18 лет.
Безопасность и эффективность финастерида у пациентов в возрасте до 18 лет не установлены.
Полная инструкция
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Финастерид-OBL таб. п/о плен.
Финастерид-OBL таб. п/о плен., 5 мг, 90 шт.
4.8
(23)
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2 вопроса
Инструкция

651 ₽

Скидка: 21%
–21 %
Вместо:824 ₽
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4.8
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У продавца:23 оценки·6 отзывов
У всех продавцов:53 оценки·13 отзывов
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user avatar
Неделю назад • Ефим Старостин • Куплен на Маркете
Достоинства: Помогает
user avatar
4 месяца назад • Фиалка • Куплен на Маркете
Достоинства: Рекомендовал врач для мужчины
Недостатки: Цена
user avatar
4 месяца назад • Валерий Г • Куплен на Маркете
Достоинства: помогает
Недостатки: как все медикаменты
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    Цена 1 468 ₽ вместо 1 483
  • Финастерид-Тева таб. п/о плен., 5 мг, 90 шт.
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    Финастерид-Тева таб. п/о плен., 5 мг, 90 шт.

    Цена 972 ₽
  • Пастилки California Gold Nutrition Vitamin D3 gummies со вкусом фруктов и ягод, 280 г, 90 шт.
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    Пастилки California Gold Nutrition Vitamin D3 gummies со вкусом фруктов и ягод, 280 г, 90 шт.

    Цена 411 ₽ вместо 443
  • Финаст таб. п/о плен., 5 мг, 30 шт.
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    Финаст таб. п/о плен., 5 мг, 30 шт.

    Цена 374 ₽
  • Силденафил-СЗ таб. п/о плен., 25 мг, 20 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1430912451_5/content/content/toggleWishlist":{"skuId":"228067804","productId":1430912451,"offerId":"uNlAZJvhE8EDIzE8cD1rTg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQsf/Rss/u9MJ3EhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIVCMP7p6oFENyT4GwYrt7QByDu3MEH","sign":"lJNsZTVrpIngGt4MJay9l3hp0qm1k0w8t+Wr3KlyY/c="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1430912451_5/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Силденафил-СЗ таб. п/о плен., 25 мг, 20 шт.

    Цена 216 ₽ вместо 266
  • Тадалафил-СЗ таб. п/о плен., 20 мг, 4 шт.
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    Тадалафил-СЗ таб. п/о плен., 20 мг, 4 шт.

    Цена 258 ₽
  • Средство для повышения тестостерона «ALPHAMAN», aTech nutrition, 90 капсул
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    Средство для повышения тестостерона «ALPHAMAN», aTech nutrition, 90 капсул

    Цена 833 ₽ вместо 1 508
  • {"widgets":{"@light/BannerCurtain":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_101_8/content/content/content/bannerCurtain":{"advertisementId":1856241,"impression":"/safeclick/data=SpQw45JhDGE6zDtOdUQO_Im9wi9o9rqYNedJU5QCZJET5LRSStAu4Bdk5Ykf4OuwB-z5yjLSk2IHDOBgmVJpaEw48aLrpswGtltVtdswlk3KHsIFL1LynmJIOOZYr3ODzNlFkWuha4ARxnSXsuOAJ3vDc1SRJ_PzRmJEpWJjTaa2Z7zbL8rh6T8py6t504-_WGA_6WMPyQPviGtO9hTGWtdkX34TeqtpLBQkrCu0xr2mAJTjOW4ltuBww5FBvISGuWjwgMZXIQ0mpYTqntpwZUkBPPMWg74a6OD4gRZ8mSzySGf2l0JLNPqjOjPs6pq2N5N1H9tRwklx1Kem9g_w0kpoOrlXL37Dc_Kf386aGp4rx-hJj97-HRrFybluvgunBMMfx2M6ilSsmOJyE9ieo2RwPjMg0k6MYX9qctkvN1dVdTm9HitRm4PgAtBuqa4C5KqXpYBRMydJZ-1NyFw-4FwMZKMotCgz2n8rR6tBAmZvwM_WLWxiyXLodxExHvHGxEW8RinouttR7kIFLKdHiP9cbVhwVoJa8MYpqzJ1iD_rlfGIXExR-V3o6OXHB5wk6DQ4snPZslz6OUAuD7dsqmAJOLcaKu8aHQum2k2OcQHrVYQ8jLjVywEGz3Na2Ddk2rYopsAfq4B7R_6ZLSx2xRp-wS6T7lyUSanyLdz8vtMIiNvN_aukf3ESfIvDzgCUfEq7osrAk6GNYs-NGO0kV9-r2z0hUr90kDTmhWVDaR92a46K7_Ce8kcY1RnolHIJo0Xxo2lEE5LgeOsqrx8jvGab-ObP6bD3XqmySMvrjhnAVWqBdwtv1B1sqPglADgHz89kwvkNycpuOAmQRmw0It1aB3bzIgGiS5Hm3KsuBNf5BTn4sRut51LAJowla0OjYlahiqusL7KNlU7Cxwd2TVpsK5D9QL5iA-Zmccm3vx8zCsh1d-JmuMz8ZFSPPtkZQ2TF7IMm6Ujnweikd4366lzbCKK3MdPDAC0TEjJqB9ZSZeqPmLLDamlcNk97jOXXlQPKHabP7d9rxeiJqa74CPAKnmtdkO3BKDMQVIHhKPVRSBlwGunrEwmbX7XneEyZ/b64e=1/sign=3b9f4a381fb578011925331c769efcc0/keyno=MARKET_1/*"}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_101_8/content/content/content/bannerCurtain":{"name":"@light/BannerCurtain"}}}
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    Реклама
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  • Алфупрост МР таб. пролонг. высвоб., 10 мг, 30 шт.
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    Алфупрост МР таб. пролонг. высвоб., 10 мг, 30 шт.

    Цена 313 ₽
  • Таблетница, 14 секций (007751)
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    Таблетница, 14 секций (007751)

    Цена 218 ₽ вместо 415
  • Контрактубекс гель, 20 мл, 20 г
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    Контрактубекс гель, 20 мл, 20 г

    Цена 845 ₽ вместо 854
  • БиоГая Пробиотик капли детск. фл., 5 мл, 1 уп.
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    БиоГая Пробиотик капли детск. фл., 5 мл, 1 уп.

    Цена 1 752 ₽ вместо 3 500
  • Профлосин капс. кш/раств. пролонг. действ., 0.4 мг, 30 шт.
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    Профлосин капс. кш/раств. пролонг. действ., 0.4 мг, 30 шт.

    Цена 431 ₽
  • Пенестер таб. п/о плен., 5 мг, 30 шт.
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    Пенестер таб. п/о плен., 5 мг, 30 шт.

    Цена 530 ₽
  • Тамсулозин ретард таб. таб. пролонг. действ., 0.4 мг, 30 шт.
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    Тамсулозин ретард таб. таб. пролонг. действ., 0.4 мг, 30 шт.

    Цена 687 ₽
  • Дутастерид-Тева капс., 0.5 мг, 30 шт.
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    Дутастерид-Тева капс., 0.5 мг, 30 шт.

    Цена 1 799 ₽
  • Бустер тестостерона Экдистерон 400 мг, БАД Ecdysterone-S 30 порций акмед средство, препарат, натуральный, тестостерон, для потенции, тестобустер, бустер тестостерона, эффективный, форте, для повышения, мышцы, масса, при эректильной дисфункции, для мужчин
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    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1840728436_17/content/content/toggleWishlist":{"skuId":"101998812884","productId":1840728436,"offerId":"ATQgrgkPtENp2vuN33VI0g","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQsf/Rss/u9MJ3EhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIXCPSS3e0GENS96fz7AhiS9vcHIICQ5gY=","sign":"jZpBtPsEj9ANblbHGGG4zMNi7O2FxikfoFF9MG6RLzo="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1840728436_17/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Бустер тестостерона Экдистерон 400 мг, БАД Ecdysterone-S 30 порций акмед средство, препарат, натуральный, тестостерон, для потенции, тестобустер, бустер тестостерона, эффективный, форте, для повышения, мышцы, масса, при эректильной дисфункции, для мужчин

    Цена 1 862 ₽ вместо 2 659
  • Дутастерид Канон капс., 0.5 мг, 30 шт.
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    Дутастерид Канон капс., 0.5 мг, 30 шт.

    Цена 1 168 ₽
  • Д-пантенол крем, 30 мл, 30 г, 1 шт., 1 уп.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1760207451_19/content/content/gallery":{"title":"Д-пантенол крем, 30 мл, 30 г, 1 шт., 1 уп.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/5332172/img_id8345483488579734595.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5332172/img_id8345483488579734595.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5332172/img_id8345483488579734595.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5332172/img_id8345483488579734595.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5332172/img_id8345483488579734595.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5332172/img_id8345483488579734595.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4828674/img_id2096778836202868879.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4828674/img_id2096778836202868879.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4828674/img_id2096778836202868879.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4828674/img_id2096778836202868879.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4828674/img_id2096778836202868879.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4828674/img_id2096778836202868879.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/5173149/img_id4031422629712138537.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5173149/img_id4031422629712138537.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5173149/img_id4031422629712138537.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5173149/img_id4031422629712138537.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5173149/img_id4031422629712138537.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5173149/img_id4031422629712138537.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/5234357/img_id8903832947996957461.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5234357/img_id8903832947996957461.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5234357/img_id8903832947996957461.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5234357/img_id8903832947996957461.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5234357/img_id8903832947996957461.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5234357/img_id8903832947996957461.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/5283489/img_id1778877284426607204.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5283489/img_id1778877284426607204.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5283489/img_id1778877284426607204.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5283489/img_id1778877284426607204.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5283489/img_id1778877284426607204.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5283489/img_id1778877284426607204.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQsf/Rss/u9MJ3EhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIXCNvEqscGEIz+xpj7AhjympgLIOXZwQc=","sign":"1YXfM2op4CTq+mdFWkGOzsR2hX0EY0uVRTTDyPctLbQ="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1760207451_19/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
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    Д-пантенол крем, 30 мл, 30 г, 1 шт., 1 уп.

    Цена 208 ₽ вместо 231
  • ЛимфоТранзит концентрат напитка фл., 100 мл
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    ЛимфоТранзит концентрат напитка фл., 100 мл

    Цена 329 ₽ вместо 390
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    Реклама
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    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  • Дапоксетин-СЗ таб. п/о плен., 30 мг, 30 шт.
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    Дапоксетин-СЗ таб. п/о плен., 30 мг, 30 шт.

    Цена 715 ₽
  • Сонирид ДУО набор таб. №30 и капс. №30, 0.4 мг, 60 шт.
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    Сонирид ДУО набор таб. №30 и капс. №30, 0.4 мг, 60 шт.

    Цена 1 449 ₽
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