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Описание

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Фуросемид таб., 40 мг, 50 шт.

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4.9
(22)
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Коротко о товаре

Артикул Маркета
2228094116
Тип препарата
Назначение
Действующее вещество
Форма выпуска
таблетки
Инструкция
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В процессе лечения режим дозирования корректируют в зависимости от величины диуретического ответа и динамики состояния пациента.\u003Cbr\u003EПри приеме внутрь начальная доза для взрослых составляет 20-80 мг/сут, далее при необходимости дозу постепенно увеличивают до 600 мг/сут. Для детей разовая доза составляет 1-2 мг/кг.\u003Cbr\u003EМаксимальная доза при приеме внутрь для детей составляет 6 мг/кг.\u003Cbr\u003EПри в/в (струйном) или в/м введении доза для взрослых составляет 20-40 мг 1 раз/сут, в отдельных случаях - 2 раза/сут. Для детей начальная суточная доза для парентерального применения - 1 мг/кг."},{"name":"Побочные действия","value":"Со стороны сердечно-сосудистой системы: снижение АД, ортостатическая гипотензия, коллапс, тахикардия, аритмии, снижение ОЦК.\u003Cbr\u003EСо стороны ЦНС и периферической нервной системы: головокружение, головная боль, миастения, судороги икроножных мышц (тетания), парестезии, апатия, адинамия, слабость, вялость, сонливость, спутанность сознания.\u003Cbr\u003EСо стороны органов чувств: нарушения зрения и слуха.\u003Cbr\u003EСо стороны пищеварительной системы: снижение аппетита, сухость во рту, жажда, тошнота, рвота, запоры или диарея, холестатическая желтуха, панкреатит (обострение).\u003Cbr\u003EСо стороны мочеполовой системы: олигурия, острая задержка мочи (у больных с гипертрофией предстательной железы), интерстициальный нефрит, гематурия, снижение потенции.\u003Cbr\u003EСо стороны системы кроветворения: лейкопения, тромбоцитопения, агранулоцитоз, апластическая анемия.\u003Cbr\u003EСо стороны водно-электролитного обмена: гиповолемия, дегидратация (риск развития тромбоза и тромбоэмболии), гипокалиемия, гипонатриемия, гипохлоремия, гипокальциемия, гипомагниемия, метаболический алкалоз.\u003Cbr\u003EСо стороны обмена веществ: гиповолемия, гипокалиемия, гипонатриемия, гипохлоремия, гипокалиемический метаболический алкалоз (как следствие этих нарушений - артериальная гипотензия, головокружение, сухость во рту, жажда, аритмия, мышечная слабость, судороги), гиперурикемия (с возможным обострением подагры), гипергликемия.\u003Cbr\u003EАллергические реакции: пурпура, крапивница, эксфолиативный дерматит, многоформная экссудативная эритема, васкулит, некротизирующий ангиит, кожный зуд, озноб, лихорадка, фотосенсибилизация, анафилактический шок.\u003Cbr\u003EПрочие: при в/в введении (дополнительно) - тромбофлебит, кальциноз почек у недоношенных детей."},{"name":"Фармакологическое действие","value":"\"Петлевой\" диуретик. Нарушает реабсорбцию ионов натрия, хлора в толстом сегменте восходящей части петли Генле. Вследствие увеличения выделения ионов натрия происходит вторичное (опосредованное осмотически связанной водой) усиленное выведение воды и увеличение секреции ионов калия в дистальной части почечного канальца. Одновременно увеличивается выведение ионов кальция и магния.\u003Cbr\u003EОбладает вторичными эффектами, обусловленными высвобождением внутрипочечных медиаторов и перераспределением внутрипочечного кровотока. На фоне курсового лечения не происходит ослабления эффекта.\u003Cbr\u003EПри сердечной недостаточности быстро приводит к снижению преднагрузки на сердце посредством расширения крупных вен. Оказывает гипотензивное действие вследствие увеличения выведения натрия хлорида и снижения реакции гладкой мускулатуры сосудов на вазоконстрикторные воздействия и в результате уменьшения ОЦК. Действие фуросемида после в/в введения наступает через 5-10 мин; после приема внутрь - через 30-60 мин, максимум действия - через 1-2 ч, продолжительность эффекта - 2-3 ч (при сниженной функции почек - до 8 ч). В период действия выведение ионов натрия значительно возрастает, однако после его прекращения скорость выведения уменьшается ниже исходного уровня (синдром \"рикошета\", или \"отмены\"). Феномен обусловлен резкой активацией ренин-ангиотензинового и других антинатрийуретических нейрогуморальных звеньев регуляции в ответ на массивный диурез; стимулирует аргинин-вазопрессивную и симпатическую системы. Уменьшает уровень предсердного натрийуретического фактора в плазме, вызывает вазоконстрикцию.\u003Cbr\u003EВследствие феномена \"рикошета\" при приеме 1 раз/сут может не оказать существенного влияния на суточное выведение ионов натрия и АД. При в/в введении вызывает дилатацию периферических вен, уменьшает преднагрузку, снижает давление наполнения левого желудочка и давление в легочной артерии, а также системное АД.\u003Cbr\u003EДиуретическое действие развивается через 3-4 мин после в/в введения и продолжается 1-2 ч; после приема внутрь - через 20-30 мин, продолжается до 4 ч."},{"name":"Фармакологическая группа","value":"диуретики"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["35947170:36763744"]}}},{"name":"Условия хранения","value":"В сухом защищенном от света месте, при температуре не выше 25°С. Хранить в недоступном для детей месте!"},{"name":"Передозировка","value":"Симптомы: выраженное снижение АД, коллапс, шок, гиповолемия, дегидратация, гемоконцентрация, аритмии (в т.ч. AV- блокада, фибрилляция желудочков), острая почечная недостаточность с анурией, тромбоз, тромбоэмболия, сонливость, спутанность сознания, вялый паралич, апатия.\u003Cbr\u003EЛечение: коррекция водно-электролитного баланса и кислотно-основного состояния, восполнение объема циркулирующей крови, промывание желудка, прием активированного угля, симптоматическое лечение. Специфического антидота нет."},{"name":"Применение при беременности и кормлении грудью","value":"С осторожностью (особенно первая половина, возможно применение по жизненным показаниям)."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В период лечения следует избегать занятий потенциально опасными видами деятельности, требующими повышенного внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"На фоне курсового лечения необходимо периодически контролировать АД, содержание электролитов плазмы крови (в т.ч. натрия, кальция, калия, магния), кислотно-основного состояния, остаточного азота, креатинина, мочевой кислоты, функции печени и проводить, при необходимости, соответствующую коррекцию лечения.\u003Cbr\u003EПациенты с повышенной чувствительностью к сульфаниламидам и производным сульфонилмочевины могут иметь перекрестную чувствительность к фуросемиду. Больным, получающим высокие дозы фуросемида, во избежание развития гипонатриемии и метаболического алкалоза нецелесообразно ограничивать потребление поваренной соли.\u003Cbr\u003EДля профилактики гипокалиемии рекомендуется одновременное назначение препаратов калия и калийсберегающих диуретиков (прежде всего спиронолактона), а также придерживаться диеты, богатой калием.\u003Cbr\u003EПодбор режима дозирования больным с асцитом на фоне цирроза печени нужно проводить в стационарных условиях (нарушения водно-электролитного баланса могут повлечь развитие печеночной комы). Данной категории больных показан регулярный контроль за содержанием электролитов плазмы.\u003Cbr\u003EПри появлении или усилении азотемии и олигурии у больных с тяжелыми прогрессирующими заболеваниями почек рекомендуется приостановить лечение. Выделяется с молоком у женщин в период лактации, в связи с чем целесообразно прекращение грудного вскармливания на период лечения.\u003Cbr\u003EУ больных с сахарным диабетом или со сниженной толерантностью к глюкозе требуется периодический контроль за уровнем глюкозы в крови и моче.\u003Cbr\u003EУ больных в бессознательном состоянии, с аденомой предстательной железы, сужением мочеточников или гидронефрозом, необходим контроль за мочеотделением, в связи с возможностью острой задержки мочи.\u003Cbr\u003E"},{"name":"Взаимодействие","value":"При одновременном применении с антибиотиками группы аминогликозидов (в т.ч. с гентамицином, тобрамицином) возможно усиление нефро- и ототоксического действия.\u003Cbr\u003EФуросемид уменьшает клиренс гентамицина и повышает концентрации в плазме крови гентамицина, а также тобрамицина.\u003Cbr\u003EПри одновременном применении с антибиотиками группы цефалоспоринов, которые могут вызывать нарушения функции почек, существует риск усиления нефротоксичности.\u003Cbr\u003EПри одновременном применении с бета-адреномиметиками (в т.ч. фенотеролом, тербуталином, сальбутамолом) и с ГКС возможно усиление гипокалиемии.\u003Cbr\u003EПри одновременном применении с гипогликемическими средствами, инсулином возможно уменьшение эффективности гипогликемических средств и инсулина, т.к. фуросемид обладает способностью повышать содержание глюкозы в плазме крови.\u003Cbr\u003EПри одновременном применении с ингибиторами АПФ усиливается антигипертензивное действие. Возможна выраженная артериальная гипотензия, особенно после приема первой дозы фуросемида, по-видимому, за счет гиповолемии, которая приводит к транзиторному усилению гипотензивного эффекта ингибиторов АПФ. Повышается риск нарушений функции почек и не исключается развитие гипокалиемии.\u003Cbr\u003EПри одновременном применении с фуросемидом усиливаются эффекты недеполяризующих миорелаксантов.\u003Cbr\u003EПри одновременном применении с индометацином, другими НПВС возможно уменьшение диуретического эффекта, по-видимому, вследствие угнетения синтеза простагландинов в почках и задержки натрия в организме под влиянием индометацина, который является неспецифическим ингибитором ЦОГ; уменьшение антигипертензивного действия.\u003Cbr\u003EПолагают, что подобным образом фуросемид взаимодействует и с другими НПВС.\u003Cbr\u003EПри одновременном применении с НПВС, которые являются селективными ингибиторами ЦОГ-2, данное взаимодействие выражено в значительно меньшей степени или практически отсутствует.\u003Cbr\u003EПри одновременном применении с астемизолом повышается риск развития аритмии.\u003Cbr\u003EПри одновременном применении с ванкомицином возможно усиление ото- и нефротоксичности.\u003Cbr\u003EПри одновременном применении с дигоксином, дигитоксином возможно повышение токсичности сердечных гликозидов, связанное с риском развития гипокалиемии на фоне приема фуросемида.\u003Cbr\u003EИмеются сообщения о развитии гипонатриемии при одновременном применении с карбамазепином.\u003Cbr\u003EПри одновременном применении с колестирамином, колестиполом уменьшается абсорбция и диуретический эффект фуросемида.\u003Cbr\u003EПри одновременном применении с лития карбонатом возможно усиление эффектов лития вследствие повышения его концентрации в плазме крови.\u003Cbr\u003EПри одновременном применении с пробенецидом уменьшается почечный клиренс фуросемида.\u003Cbr\u003EПри одновременном применении с соталолом возможна гипокалиемия и развитие желудочковой аритмии типа \"пируэт\".\u003Cbr\u003EПри одновременном применении с теофиллином возможно изменение концентрации теофиллина в плазме крови.\u003Cbr\u003EПри одновременном применении с фенитоином значительно уменьшается диуретическое действие фуросемида.\u003Cbr\u003EПосле в/в введения фуросемида на фоне терапии хлоралгидратом возможно повышение потоотделения, чувство жара, нестабильность АД, тахикардия.\u003Cbr\u003EПри одновременном применении с цизапридом возможно усиление гипокалиемии.\u003Cbr\u003EПредполагается, что фуросемид может уменьшать нефротоксическое действие циклоспорина.\u003Cbr\u003EПри одновременном применении с цисплатином возможно усиление ототоксического действия."},{"name":"Регистрационный номер","value":"P N003233/01"},{"name":"Дата государственной регистрации","value":"17.10.2019"},{"name":"Владелец регистрационного удостоверения","value":"Атолл","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["34324371:35649313","7893318:17601668"]}}},{"name":"Изготовитель","value":"ОЗОН"},{"name":"Фасовщик","value":"ОЗОН"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Фуросемид","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["17796364:18003817"]}}},{"name":"Срок годности","value":"23 мес."}]}},"fullSpecsGrouped":{"10630423241518214993":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"кровеносные сосуды, сердце"},{"name":"Назначение","value":"артериальная гипертензия, отек легких, отеки, вызванные сердечной недостаточностью, заболеваниями печени, почек и легких, отечный синдром различного генеза"},{"name":"Показания к применению","value":"Отечный синдром различного генеза, в т.ч. при хронической сердечной недостаточности II-III стадии, циррозе печени (синдром портальной гипертензии), нефротическом синдроме. Отек легких, сердечная астма, отек мозга, эклампсия, проведение форсированного диуреза, артериальная гипертензия тяжелого течения, некоторые формы гипертонического криза, гиперкальциемия."},{"name":"Противопоказания","value":"Повышенная чувствительность к фуросемиду, острая почечная недостаточность с анурией (величина клубочковой фильтрации менее 3-5 мл/мин), тяжелая печеночная недостаточность, печеночная кома, стеноз мочеиспускательного канала, острый гломерулонефрит, обструкция мочевыводящих путей камнем, прекоматозные состояния, гипергликемическая кома, гиперурикемия, подагра, декомпенсированный митральный или аортальный стеноз, повышение центрального венозного давления (свыше 10 мм рт.ст.), идиопатический гипертрофический субаортальный стеноз, артериальная гипотензия, острый инфаркт миокарда, системная красная волчанка, панкреатит, нарушение водно-электролитного обмена (гиповолемия, гипонатриемия, гипокалиемия, гипохлоремия, гипокальциемия, гипомагниемия), дигиталисная интоксикация. С осторожностью: доброкачественная гиперплазия предстательной железы, гипопротеинемия (риск развития ототоксичности), сахарный диабет (снижение толерантности к глюкозе), стенозирующий атеросклероз церебральных артерий, беременность (особенно первая половина, возможно применение по жизненным показаниям), период лактации."},{"name":"Состав","value":"Активное вещество: Фуросемид 40,0 мг\u003Cbr\u003EВспомогательные вещества: лактозы моногидрат (сахар молочный) - 67,40 мг, целлюлоза микрокристаллическая - 20,0 мг, крахмал кукурузный - 15,0 мг, повидон (поливинилпирролидон) - 5,40 мг, кремния диоксид коллоидный - 0,70 мг, магния стеарат - 1,50 мг.\u003Cbr\u003E"},{"name":"Действующее вещество","value":"Фуросемид"},{"name":"Способ применения и дозы","value":"Устанавливают индивидуально, в зависимости от показаний, клинической ситуации, возраста пациента. В процессе лечения режим дозирования корректируют в зависимости от величины диуретического ответа и динамики состояния пациента.\u003Cbr\u003EПри приеме внутрь начальная доза для взрослых составляет 20-80 мг/сут, далее при необходимости дозу постепенно увеличивают до 600 мг/сут. Для детей разовая доза составляет 1-2 мг/кг.\u003Cbr\u003EМаксимальная доза при приеме внутрь для детей составляет 6 мг/кг.\u003Cbr\u003EПри в/в (струйном) или в/м введении доза для взрослых составляет 20-40 мг 1 раз/сут, в отдельных случаях - 2 раза/сут. Для детей начальная суточная доза для парентерального применения - 1 мг/кг."},{"name":"Побочные действия","value":"Со стороны сердечно-сосудистой системы: снижение АД, ортостатическая гипотензия, коллапс, тахикардия, аритмии, снижение ОЦК.\u003Cbr\u003EСо стороны ЦНС и периферической нервной системы: головокружение, головная боль, миастения, судороги икроножных мышц (тетания), парестезии, апатия, адинамия, слабость, вялость, сонливость, спутанность сознания.\u003Cbr\u003EСо стороны органов чувств: нарушения зрения и слуха.\u003Cbr\u003EСо стороны пищеварительной системы: снижение аппетита, сухость во рту, жажда, тошнота, рвота, запоры или диарея, холестатическая желтуха, панкреатит (обострение).\u003Cbr\u003EСо стороны мочеполовой системы: олигурия, острая задержка мочи (у больных с гипертрофией предстательной железы), интерстициальный нефрит, гематурия, снижение потенции.\u003Cbr\u003EСо стороны системы кроветворения: лейкопения, тромбоцитопения, агранулоцитоз, апластическая анемия.\u003Cbr\u003EСо стороны водно-электролитного обмена: гиповолемия, дегидратация (риск развития тромбоза и тромбоэмболии), гипокалиемия, гипонатриемия, гипохлоремия, гипокальциемия, гипомагниемия, метаболический алкалоз.\u003Cbr\u003EСо стороны обмена веществ: гиповолемия, гипокалиемия, гипонатриемия, гипохлоремия, гипокалиемический метаболический алкалоз (как следствие этих нарушений - артериальная гипотензия, головокружение, сухость во рту, жажда, аритмия, мышечная слабость, судороги), гиперурикемия (с возможным обострением подагры), гипергликемия.\u003Cbr\u003EАллергические реакции: пурпура, крапивница, эксфолиативный дерматит, многоформная экссудативная эритема, васкулит, некротизирующий ангиит, кожный зуд, озноб, лихорадка, фотосенсибилизация, анафилактический шок.\u003Cbr\u003EПрочие: при в/в введении (дополнительно) - тромбофлебит, кальциноз почек у недоношенных детей."},{"name":"Фармакологическое действие","value":"\"Петлевой\" диуретик. Нарушает реабсорбцию ионов натрия, хлора в толстом сегменте восходящей части петли Генле. Вследствие увеличения выделения ионов натрия происходит вторичное (опосредованное осмотически связанной водой) усиленное выведение воды и увеличение секреции ионов калия в дистальной части почечного канальца. Одновременно увеличивается выведение ионов кальция и магния.\u003Cbr\u003EОбладает вторичными эффектами, обусловленными высвобождением внутрипочечных медиаторов и перераспределением внутрипочечного кровотока. На фоне курсового лечения не происходит ослабления эффекта.\u003Cbr\u003EПри сердечной недостаточности быстро приводит к снижению преднагрузки на сердце посредством расширения крупных вен. Оказывает гипотензивное действие вследствие увеличения выведения натрия хлорида и снижения реакции гладкой мускулатуры сосудов на вазоконстрикторные воздействия и в результате уменьшения ОЦК. Действие фуросемида после в/в введения наступает через 5-10 мин; после приема внутрь - через 30-60 мин, максимум действия - через 1-2 ч, продолжительность эффекта - 2-3 ч (при сниженной функции почек - до 8 ч). В период действия выведение ионов натрия значительно возрастает, однако после его прекращения скорость выведения уменьшается ниже исходного уровня (синдром \"рикошета\", или \"отмены\"). Феномен обусловлен резкой активацией ренин-ангиотензинового и других антинатрийуретических нейрогуморальных звеньев регуляции в ответ на массивный диурез; стимулирует аргинин-вазопрессивную и симпатическую системы. Уменьшает уровень предсердного натрийуретического фактора в плазме, вызывает вазоконстрикцию.\u003Cbr\u003EВследствие феномена \"рикошета\" при приеме 1 раз/сут может не оказать существенного влияния на суточное выведение ионов натрия и АД. При в/в введении вызывает дилатацию периферических вен, уменьшает преднагрузку, снижает давление наполнения левого желудочка и давление в легочной артерии, а также системное АД.\u003Cbr\u003EДиуретическое действие развивается через 3-4 мин после в/в введения и продолжается 1-2 ч; после приема внутрь - через 20-30 мин, продолжается до 4 ч."},{"name":"Фармакологическая группа","value":"диуретики"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"В сухом защищенном от света месте, при температуре не выше 25°С. Хранить в недоступном для детей месте!"},{"name":"Передозировка","value":"Симптомы: выраженное снижение АД, коллапс, шок, гиповолемия, дегидратация, гемоконцентрация, аритмии (в т.ч. AV- блокада, фибрилляция желудочков), острая почечная недостаточность с анурией, тромбоз, тромбоэмболия, сонливость, спутанность сознания, вялый паралич, апатия.\u003Cbr\u003EЛечение: коррекция водно-электролитного баланса и кислотно-основного состояния, восполнение объема циркулирующей крови, промывание желудка, прием активированного угля, симптоматическое лечение. Специфического антидота нет."},{"name":"Применение при беременности и кормлении грудью","value":"С осторожностью (особенно первая половина, возможно применение по жизненным показаниям)."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В период лечения следует избегать занятий потенциально опасными видами деятельности, требующими повышенного внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"На фоне курсового лечения необходимо периодически контролировать АД, содержание электролитов плазмы крови (в т.ч. натрия, кальция, калия, магния), кислотно-основного состояния, остаточного азота, креатинина, мочевой кислоты, функции печени и проводить, при необходимости, соответствующую коррекцию лечения.\u003Cbr\u003EПациенты с повышенной чувствительностью к сульфаниламидам и производным сульфонилмочевины могут иметь перекрестную чувствительность к фуросемиду. Больным, получающим высокие дозы фуросемида, во избежание развития гипонатриемии и метаболического алкалоза нецелесообразно ограничивать потребление поваренной соли.\u003Cbr\u003EДля профилактики гипокалиемии рекомендуется одновременное назначение препаратов калия и калийсберегающих диуретиков (прежде всего спиронолактона), а также придерживаться диеты, богатой калием.\u003Cbr\u003EПодбор режима дозирования больным с асцитом на фоне цирроза печени нужно проводить в стационарных условиях (нарушения водно-электролитного баланса могут повлечь развитие печеночной комы). Данной категории больных показан регулярный контроль за содержанием электролитов плазмы.\u003Cbr\u003EПри появлении или усилении азотемии и олигурии у больных с тяжелыми прогрессирующими заболеваниями почек рекомендуется приостановить лечение. Выделяется с молоком у женщин в период лактации, в связи с чем целесообразно прекращение грудного вскармливания на период лечения.\u003Cbr\u003EУ больных с сахарным диабетом или со сниженной толерантностью к глюкозе требуется периодический контроль за уровнем глюкозы в крови и моче.\u003Cbr\u003EУ больных в бессознательном состоянии, с аденомой предстательной железы, сужением мочеточников или гидронефрозом, необходим контроль за мочеотделением, в связи с возможностью острой задержки мочи.\u003Cbr\u003E"},{"name":"Взаимодействие","value":"При одновременном применении с антибиотиками группы аминогликозидов (в т.ч. с гентамицином, тобрамицином) возможно усиление нефро- и ототоксического действия.\u003Cbr\u003EФуросемид уменьшает клиренс гентамицина и повышает концентрации в плазме крови гентамицина, а также тобрамицина.\u003Cbr\u003EПри одновременном применении с антибиотиками группы цефалоспоринов, которые могут вызывать нарушения функции почек, существует риск усиления нефротоксичности.\u003Cbr\u003EПри одновременном применении с бета-адреномиметиками (в т.ч. фенотеролом, тербуталином, сальбутамолом) и с ГКС возможно усиление гипокалиемии.\u003Cbr\u003EПри одновременном применении с гипогликемическими средствами, инсулином возможно уменьшение эффективности гипогликемических средств и инсулина, т.к. фуросемид обладает способностью повышать содержание глюкозы в плазме крови.\u003Cbr\u003EПри одновременном применении с ингибиторами АПФ усиливается антигипертензивное действие. Возможна выраженная артериальная гипотензия, особенно после приема первой дозы фуросемида, по-видимому, за счет гиповолемии, которая приводит к транзиторному усилению гипотензивного эффекта ингибиторов АПФ. Повышается риск нарушений функции почек и не исключается развитие гипокалиемии.\u003Cbr\u003EПри одновременном применении с фуросемидом усиливаются эффекты недеполяризующих миорелаксантов.\u003Cbr\u003EПри одновременном применении с индометацином, другими НПВС возможно уменьшение диуретического эффекта, по-видимому, вследствие угнетения синтеза простагландинов в почках и задержки натрия в организме под влиянием индометацина, который является неспецифическим ингибитором ЦОГ; уменьшение антигипертензивного действия.\u003Cbr\u003EПолагают, что подобным образом фуросемид взаимодействует и с другими НПВС.\u003Cbr\u003EПри одновременном применении с НПВС, которые являются селективными ингибиторами ЦОГ-2, данное взаимодействие выражено в значительно меньшей степени или практически отсутствует.\u003Cbr\u003EПри одновременном применении с астемизолом повышается риск развития аритмии.\u003Cbr\u003EПри одновременном применении с ванкомицином возможно усиление ото- и нефротоксичности.\u003Cbr\u003EПри одновременном применении с дигоксином, дигитоксином возможно повышение токсичности сердечных гликозидов, связанное с риском развития гипокалиемии на фоне приема фуросемида.\u003Cbr\u003EИмеются сообщения о развитии гипонатриемии при одновременном применении с карбамазепином.\u003Cbr\u003EПри одновременном применении с колестирамином, колестиполом уменьшается абсорбция и диуретический эффект фуросемида.\u003Cbr\u003EПри одновременном применении с лития карбонатом возможно усиление эффектов лития вследствие повышения его концентрации в плазме крови.\u003Cbr\u003EПри одновременном применении с пробенецидом уменьшается почечный клиренс фуросемида.\u003Cbr\u003EПри одновременном применении с соталолом возможна гипокалиемия и развитие желудочковой аритмии типа \"пируэт\".\u003Cbr\u003EПри одновременном применении с теофиллином возможно изменение концентрации теофиллина в плазме крови.\u003Cbr\u003EПри одновременном применении с фенитоином значительно уменьшается диуретическое действие фуросемида.\u003Cbr\u003EПосле в/в введения фуросемида на фоне терапии хлоралгидратом возможно повышение потоотделения, чувство жара, нестабильность АД, тахикардия.\u003Cbr\u003EПри одновременном применении с цизапридом возможно усиление гипокалиемии.\u003Cbr\u003EПредполагается, что фуросемид может уменьшать нефротоксическое действие циклоспорина.\u003Cbr\u003EПри одновременном применении с цисплатином возможно усиление ототоксического действия."},{"name":"Регистрационный номер","value":"P N003233/01"},{"name":"Дата государственной регистрации","value":"17.10.2019"},{"name":"Владелец регистрационного удостоверения","value":"Атолл"},{"name":"Изготовитель","value":"ОЗОН"},{"name":"Фасовщик","value":"ОЗОН"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Фуросемид"},{"name":"Срок годности","value":"23 мес."}]}],"transitionId":"tr_11981071114774423730"}}}}
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Инструкция

Показания к применению

Отечный синдром различного генеза, в т.ч. при хронической сердечной недостаточности II-III стадии, циррозе печени (синдром портальной гипертензии), нефротическом синдроме. Отек легких, сердечная астма, отек мозга, эклампсия, проведение форсированного диуреза, артериальная гипертензия тяжелого течения, некоторые формы гипертонического криза, гиперкальциемия.

Противопоказания

Повышенная чувствительность к фуросемиду, острая почечная недостаточность с анурией (величина клубочковой фильтрации менее 3-5 мл/мин), тяжелая печеночная недостаточность, печеночная кома, стеноз мочеиспускательного канала, острый гломерулонефрит, обструкция мочевыводящих путей камнем, прекоматозные состояния, гипергликемическая кома, гиперурикемия, подагра, декомпенсированный митральный или аортальный стеноз, повышение центрального венозного давления (свыше 10 мм рт.ст.), идиопатический гипертрофический субаортальный стеноз, артериальная гипотензия, острый инфаркт миокарда, системная красная волчанка, панкреатит, нарушение водно-электролитного обмена (гиповолемия, гипонатриемия, гипокалиемия, гипохлоремия, гипокальциемия, гипомагниемия), дигиталисная интоксикация. С осторожностью: доброкачественная гиперплазия предстательной железы, гипопротеинемия (риск развития ототоксичности), сахарный диабет (снижение толерантности к глюкозе), стенозирующий атеросклероз церебральных артерий, беременность (особенно первая половина, возможно применение по жизненным показаниям), период лактации.

Способ применения и дозы

Устанавливают индивидуально, в зависимости от показаний, клинической ситуации, возраста пациента. В процессе лечения режим дозирования корректируют в зависимости от величины диуретического ответа и динамики состояния пациента.
При приеме внутрь начальная доза для взрослых составляет 20-80 мг/сут, далее при необходимости дозу постепенно увеличивают до 600 мг/сут. Для детей разовая доза составляет 1-2 мг/кг.
Максимальная доза при приеме внутрь для детей составляет 6 мг/кг.
При в/в (струйном) или в/м введении доза для взрослых составляет 20-40 мг 1 раз/сут, в отдельных случаях - 2 раза/сут. Для детей начальная суточная доза для парентерального применения - 1 мг/кг.
Полная инструкция
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Фуросемид таб.
Фуросемид таб., 40 мг, 50 шт.
4.9
(22)
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12 вопросов
Инструкция
Нет в продаже
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4.9
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У продавца:22 оценки·2 отзыва
У всех продавцов:98 оценок·22 отзыва
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6 месяцев назад • Имя скрыто • Куплен на Маркете
Достоинства: хорошо работает, принимаем всей семьёй много лет
Недостатки: нет
user avatar
5 месяцев назад • Надежда Петрова • Куплен на Маркете
Комментарий: Как экстренно и быстро
Посмотреть все отзывы на Маркете
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    Vitamin D3, 2000 ME, 120 шт.

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    Пастилки California Gold Nutrition Vitamin D3 gummies со вкусом фруктов и ягод, 280 г, 90 шт.

    Цена 2 005 ₽ вместо 2 800
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    Панангин таб. п/о плен., 50 шт.

    Цена 188 ₽ вместо 224
  • Марлевый Бинт медицинский стерильный Вариант 5 м х 10 см ГОСТ, 5 шт. в наборе
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    Марлевый Бинт медицинский стерильный Вариант 5 м х 10 см ГОСТ, 5 шт. в наборе

    Цена 190 ₽ вместо 280
  • Gummies B Complex со вкусом клубники, 220 г, 45 шт., клубника
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1803896484_4/content/content/gallery":{"title":"Gummies B Complex со вкусом клубники, 220 г, 45 шт., клубника","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/5273154/img_id2865486918753844475.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5273154/img_id2865486918753844475.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5273154/img_id2865486918753844475.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5273154/img_id2865486918753844475.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5273154/img_id2865486918753844475.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5273154/img_id2865486918753844475.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/5307186/img_id8430767242374483406.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5307186/img_id8430767242374483406.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5307186/img_id8430767242374483406.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5307186/img_id8430767242374483406.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5307186/img_id8430767242374483406.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5307186/img_id8430767242374483406.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/5236803/img_id6868855409809313229.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5236803/img_id6868855409809313229.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5236803/img_id6868855409809313229.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5236803/img_id6868855409809313229.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5236803/img_id6868855409809313229.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5236803/img_id6868855409809313229.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/5347553/img_id6229910567386382683.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5347553/img_id6229910567386382683.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5347553/img_id6229910567386382683.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5347553/img_id6229910567386382683.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5347553/img_id6229910567386382683.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5347553/img_id6229910567386382683.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4700988/img_id8489018710454043082.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4700988/img_id8489018710454043082.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4700988/img_id8489018710454043082.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4700988/img_id8489018710454043082.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4700988/img_id8489018710454043082.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4700988/img_id8489018710454043082.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ/f3969OYtf5pEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCKSNldwGEKuO/8v7Ahje0N0GIJnDBQ==","sign":"bfQ1iaTePKdBknCpq561FdX5QtUSOdJgkEpdDZQwtzU="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1803896484_4/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
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    Gummies B Complex со вкусом клубники, 220 г, 45 шт., клубника

    Цена 1 397 ₽ вместо 3 500
  • Эвалар Чай Эвалар БИО при повышенном содержании мочевой кислоты, 20 фильтр-пакетов
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    Эвалар Чай Эвалар БИО при повышенном содержании мочевой кислоты, 20 фильтр-пакетов

    Цена 236 ₽ вместо 238
  • Пиколинат хрома для снижения аппетита, контроль веса, контроль сахара в крови, 60 капсул
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    Пиколинат хрома для снижения аппетита, контроль веса, контроль сахара в крови, 60 капсул

    Цена 351 ₽ вместо 683
  • Бинт эластичный самофиксирующийся / бандажная лента для животных, для перевязок, для тату, 5 см х 4,5 м, черный, 1 шт
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    Бинт эластичный самофиксирующийся / бандажная лента для животных, для перевязок, для тату, 5 см х 4,5 м, черный, 1 шт

    Цена 127 ₽ вместо 300
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    Реклама
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  • Omega-3 капс., 1000 мг, 100 мл, 30 шт.
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    Omega-3 капс., 1000 мг, 100 мл, 30 шт.

    Цена 594 ₽ вместо 600
  • Таблетница из 14 секций на семь дней Утро-вечер
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    Таблетница из 14 секций на семь дней Утро-вечер

    Цена 177 ₽ вместо 220
  • Янтарная кислота для укрепления иммунитета, нормализации сна, для стрессоустойчивости, для похудения 60 капс
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    Янтарная кислота для укрепления иммунитета, нормализации сна, для стрессоустойчивости, для похудения 60 капс

    Цена 328 ₽ вместо 721
  • Пантовигар капс., 90 шт.
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    Пантовигар капс., 90 шт.

    Цена 1 759 ₽ вместо 1 777
  • Магне B6 таб. п/о, 60 шт.
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    Магне B6 таб. п/о, 60 шт.

    Цена 610 ₽ вместо 681
  • VETTA / Таблетница-органайзер для таблеток аптечка для лекарств карманная в дорогу с разделителем на 14 секций, на неделю 7 дней, утро вечер
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    VETTA / Таблетница-органайзер для таблеток аптечка для лекарств карманная в дорогу с разделителем на 14 секций, на неделю 7 дней, утро вечер

    Цена 350 ₽ вместо 950
  • Эвалар чай Турбослим Очищение ф/п, 2 г, 20 шт.
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    Эвалар чай Турбослим Очищение ф/п, 2 г, 20 шт.

    Цена 358 ₽ вместо 362
  • Бинт медицинский стерильный 5х10 New Life -10 шт
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    Бинт медицинский стерильный 5х10 New Life -10 шт

    Цена 250 ₽ вместо 390
  • Магне-В6 р-р д/вн. приема амп., 10 шт.
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    Магне-В6 р-р д/вн. приема амп., 10 шт.

    Цена 660 ₽ вместо 667
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