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Описание

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Грандаксин таб., 50 мг, 20 шт.

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4.7
(17)
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Количество штук в упаковке, шт.: 20

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Коротко о товаре

Артикул Маркета
4453156552
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
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тофизопама, а также вспомогательные вещества: стеариновую кислоту 1 мг, магния стеарат 1 мг, желатин 3,5 мг, тальк 2 мг, крахмал картофельный 20,5 мг, лактозы моногидрат 92 мг, целлюлозу микрокристаллическую 10 мг."},{"name":"Действующее вещество","value":"Тофизопам","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["27144131:28710264"]}}},{"name":"Способ применения и дозы","value":"Взрослые\u003Cbr\u003EОбычно рекомендуемая доза: 1 - 2 таблетки от 1 до З раз в день (общая суточная доза от 50 до 300 мг).\nПри нерегулярном применении можно принять - 2 таблетки.\nМаксимальная доза составляет 300 мг.\nПостепенное повышение дозы обычно не требуется лечение можно начинать с необходимой дозы, т.к. препарат хорошо переносим и во время его приема обычно не наблюдается уменьшение активности и психического бодрствования.\u003Cbr\u003EДети и подростки в возрасте до 18 лет\u003Cbr\u003EПрименение у детей и подростков до 18 лет противопоказано. Отсутствует достаточный опыт применения препарата у детей и подростков до 18 лет.\u003Cbr\u003EОсобые группы пациентов\u003Cbr\u003EИнформация об особых группах пациентов отсутствует. Клинических исследований, изучающих эффективность и безопасность препарата Грандаксин таблетки 50 мг (тофизопам) у пожилых, у пациентов с почечной и печеночной недостаточностью не проводилось."},{"name":"Побочные действия","value":"Нежелательные реакции приводятся ниже по классам систем органов и частоте: очень часто ( ≥ 1/10), часто ( ≥ 1/100 - \u003C 1/10), нечасто ( ≥ 1/1000 - ≤ 1/100), редко ( ≥ 1/10000 - ≤ 1/1000), очень редко (≤ 1/10 000) или наблюдаемые с неизвестной частотой (невозможно оценить на основании имеющихся данных).\nВ каждой частотной категории нежелательные реакции приводятся в порядке уменьшения их тяжести.\nДля большинства нежелательных реакций отсутствуют данные для определения их частоты.\u003Cbr\u003EНарушения психики:\u003Cbr\u003EОчень редко: спутанное сознание;\u003Cbr\u003EЧастота неизвестна: возбуждение, повышенная раздражимость, ощущение психического напряжения, ухудшение аппетита.\u003Cbr\u003EНарушения со стороны нервной системы:\u003Cbr\u003EБессонница, очень редко препарат может провоцировать судорожные припадки у пациентов с эпилепсией.\u003Cbr\u003EНарушения со стороны дыхательной системы, органов грудной метки и средостения:\u003Cbr\u003EУгнетение дыхания\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта:\u003Cbr\u003EТошнота, рвота, запор, метеоризм, сухость во рту\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей:\u003Cbr\u003EОчень редко: холестатическая желтуха\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей:\u003Cbr\u003EЭкзантема, скарлатиноподобная экзантема\u003Cbr\u003EНарушения со стороны костном, мышечном и соединительной ткани:\u003Cbr\u003EНапряжение мышц, боль в мышцах.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения:\u003Cbr\u003EГоловная боль, кожный зуд."},{"name":"Фармакологическое действие","value":"Тофизопам является мягким анксиолитиком с кратковременным действием и широким терапевтическим индексом. Точный механизм действия неизвестен. Как по химической структуре, так и по клинико-фармакологическому эффекту тофизопам отличается от других 1 ,4-бензодиазепинов.\nПрепарат эффективен при лечении тревожных расстройств, в том числе сопровождающихся вегетативными проявлениями, усталостью, апатией. В отличие от других бензодиазепинов, тофизопам не обладает седативным, снотворным, миорелаксирующим и противосудорожным действием. Препарат не оказывает неблагоприятного действия на память, психомоторную и когнитивную функцию, но обладает умеренной стимулирующей активностью.\nВследствие отсутствия миорелаксирующего эффекта препарат может применяться и у пациентов с миопатией, миастенией и нейрогенными атрофиями мышц, при которых применение миорелаксантов противопоказано или нежелательно. При длительном применении тофизопам не вызывает развитие физической или психической зависимости."},{"name":"Фармакологическая группа","value":"анксиолитическое средство (транквилизатор)"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"Хранить препарат при температуре от 15 до 25 °С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы: эффекты подавления функции центральной нервной системы (ЦНС) проявляются только после приема высоких доз (50 - 120 мг/кг массы тела). Такие дозы могут вызвать рвоту, спутанное сознание, кому, угнетение дыхания и/или эпилептические припадки.\u003Cbr\u003EЛечение: при выраженном подавлении функций ЦНС не рекомендуется вызывать рвоту. Промывание желудка. Введение активированного угля и применение слабительных помогает уменьшить всасывание препарата. Следует постоянно следить за основными физиологическими параметрами и применять соответствующую симптоматическую терапию. При угнетении дыхания следует проводить искусственную вентиляцию легких. Введение стимуляторов ЦНС не рекомендуется. Гипотензию лучше всего устранять в/в введением жидкостей и переводом пациента в положение Тренделенбурга. Если эти меры не восстанавливают уровень артериального давления (АД), можно ввести дофамин или норадреналин. Диализ и вызванный диурез не эффективны.\nВ качестве антагониста можно ввести флумазенил, однако, его применение при передозировке тофизопамом клинически не протестировано."},{"name":"Применение при беременности и кормлении грудью","value":"Беременность\u003Cbr\u003EТофизопам проникает через плацентарный барьер. Применение этого препарата при беременности противопоказано.\u003Cbr\u003EПериод грудного вскармливания\u003Cbr\u003EПрепарат выделяется в грудное молоко, поэтому не рекомендуется его применять во время грудного вскармливания."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В период применения препарата запрещено вождение транспортных средств или работа со сложными механизмами, требующими повышенной концентрации внимания."},{"name":"Особые указания","value":"Необходима особая осторожность при лечении пациентов с компенсированной хронической дыхательной недостаточностью или ранее перенесших острую дыхательную недостаточность.\u003Cbr\u003EОсторожность необходима при лечении пожилых пациентов и лиц с психической деградацией, а также имеющих нарушения функции почек и/или печени, т.к. у них чаще, чем у других пациентов, наблюдаются нежелательные реакции препарата.\u003Cbr\u003EПри сочетании препарата Грандаксин с препаратами, подавляющими функцию ЦНС (антидепрессанты, седативные, снотворные, опиоидные аналгетики, средства общей анестезии), антигистаминными препаратами, антипсихотическими, алкоголем возможно усиление взаимных эффектов.\u003Cbr\u003EНе рекомендуется применять препарат при хроническом психозе, фобии или навязчивых состояниях. При уменьшении торможения возрастает риск суицидальных попыток и агрессивного поведения. Поэтому Грандаксин не рекомендуется в качестве монотерапии депрессии или депрессии, сопровождающейся с тревогой.\u003Cbr\u003EНеобходима осторожность при лечении пациентов с расстройствами личности (психопатии).\u003Cbr\u003EПрепарат следует применять с повышенной осторожностью при органических поражениях головного мозга (например, при атеросклерозе).\u003Cbr\u003EУ пациентов с эпилепсией Грандаксин может провоцировать судорожные припадки.\u003Cbr\u003EНе рекомендуется применять этот препарат пациентам с закрытоугольной глаукомой.\u003Cbr\u003EРиск при совместном применении с опиоидами\u003Cbr\u003EСовместное применение препарата Грандаксин с опиоидами повышает риск седации, угнетения дыхания, комы и смертельного исхода. В связи с повышенным риском совместное применение седативных препаратов возможно лишь у пациентов, для которых невозможно применение альтернативных методов лечения. Если принято решение об одновременном назначении препарата Грандаксин с другими седативными лекарственными средствами, следует использовать самые низкие эффективные дозы, а продолжительность лечения должна быть как можно короче. Таким пациентам необходим тщательный контроль симптомов угнетения дыхания и седации. В связи с этим настоятельно рекомендуется ознакомить пациентов и ухаживающих за ними лиц (при наличии таковых) о симптомах угнетения дыхания и седации.\u003Cbr\u003EПрепарат Грандаксин содержит лактозу\u003Cbr\u003EКаждая таблетка Грандаксин содержит 92 мг лактозы моногидрата. Это следует учитывать пациентам, страдающим редкими наследственными заболеваниями, в том числе непереносимостью галактозы, полной лактазной недостаточностью и мальабсорбцией глюкозы/галактозы.\u003Cbr\u003EС осторожностью:\u003Cbr\u003EНе декомпенсированная хроническая дыхательная недостаточность, острая дыхательная недостаточность в анамнезе, закрытоугольная глаукома, эпилепсия, органические поражения головного мозга (например, атеросклероз). Пожилые пациенты и пациенты с нарушением функции печени или почек. Совместное применение с опиоидами."},{"name":"Взаимодействие","value":"Концентрация в плазме крови препаратов, которые метаболизируются изоферментом СYРЗА4, может увеличиться при одновременном приеме с тофизопамом, поэтому одновременное применение такролимуса, сиролимуса, циклоспорина и тофизопама противопоказано.\u003Cbr\u003EПрименение тофизопама с препаратами, оказывающими угнетающее действие на ЦНС (анальгетики, средства общей анестезии, антидепрессанты, седативные, снотворные,),\nН1- гистаминовых рецепторов блокаторами, антипсихотическими, усиливает их эффекты (например, седативный эффект или угнетение дыхания).\u003Cbr\u003EОпиоиды. Совместное применение лекарственных средств с седативным действием, таких как бензодиазепины или подобные им препараты, такие как Грандаксин, с опиодами повышает риск седации, угнетения дыхания, комы и смертельного исхода в связи с аддитивным угнетающим эффектом этих препаратов на ЦНС. Дозы и продолжительность совместного применения таких препаратов должны быть ограничены\u003Cbr\u003EИндукторы печеночных ферментов (алкоголь, никотин, барбитураты, противоэпилептические средства) могут усилить метаболизм тофизопама, что может привести к снижению его концентрации в плазме крови и ослаблению терапевтического эффекта.\u003Cbr\u003EНекоторые противогрибковые препараты (кетоконазол, итраконазол) могут замедлить печеночный метаболизм тофизопама, что приводит к увеличению его концентрации в плазме крови.\u003Cbr\u003EНекоторые гипотензивные препараты (клонидин, блокаторы «медленных» кальциевых каналов) могут усилить эффекты тофизопама. β-адреноблокаторы могут замедлить метаболизм препарата, однако этот эффект не имеет клинического значения.\u003Cbr\u003EДигоксин: тофизопам может повысить концентрацию дигоксина в плазме крови.\u003Cbr\u003EВарфарин: бензодиазепины могут повлиять на антикоагулянтный эффект варфарина. Дисульфирам: длительное применение дисульфирама может угнетать метаболизм тофизопама.\u003Cbr\u003EАнтацидные средства по-разному влияют на всасывание тофизопама. Циметидин и омепразол угнетают метаболизм тофизопама.\u003Cbr\u003EПероральные контрацептивные средства могут снижать интенсивность метаболизма тофизопама.\u003Cbr\u003EАлкоголь: тофизопам ослабляет угнетающее действие алкоголя на перцепцию."},{"name":"Регистрационный номер","value":"ЛП-№(000172)-(РГ-RU)"},{"name":"Дата государственной регистрации","value":"24.03.2021"},{"name":"Владелец регистрационного удостоверения","value":"Egis Pharmaceuticals","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["34324371:35649313","7893318:16002706"]}}},{"name":"Изготовитель","value":"Фармацевтический завод ЭГИС"},{"name":"Фасовщик","value":"Фармацевтический завод ЭГИС"},{"name":"Страна бренда","value":"Венгрия"},{"name":"Страна-производитель","value":"Венгрия"},{"name":"Название препарата","value":"Грандаксин","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["17796364:18020903"]}}},{"name":"Срок годности","value":"60 мес."}]}},"fullSpecsGrouped":{"9852811586869935446":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"нервная система"},{"name":"Назначение","value":"депрессия, климакс, невроз, предменструальный синдром, расстройства эмоциональной сферы, синдром алкогольной абстиненции, тревожные расстройства, функциональные вегетативные расстройства, функциональные кардиалгии"},{"name":"Показания к применению","value":"Лечение психических (невротических) и психосоматических расстройств, сопровождающихся эмоциональным напряжением, тревогой, вегетативными расстройствами, апатией, усталостью и подавленным настроением.\nАлкогольный абстинентный синдром."},{"name":"Противопоказания","value":"Повышенная чувствительность к тофизопаму, другим производным группы бензодиазепина, а также другим компонентам препарата;\u003Cbr\u003Eдетский возраст до 18 лет;\u003Cbr\u003Eбеременность;\u003Cbr\u003Eпериод грудного вскармливания;\u003Cbr\u003Eсостояния, сопровождающиеся выраженным психомоторным возбуждением, агрессией или выраженной депрессией;\u003Cbr\u003Eдекомпенсированная дыхательная недостаточность;\u003Cbr\u003Eсиндром обструктивного апноэ;\u003Cbr\u003Eкома;\u003Cbr\u003Eодновременное применение с такролимусом, сиролимусом, циклоспорином;\u003Cbr\u003Eдефицит лактазы, непереносимость лактозы, глюкозо-галактозная мальабсорбция (препарат содержит лактозы моногидрат)."},{"name":"Состав","value":"1 таблетка содержит 50 мг активного вещества - тофизопама, а также вспомогательные вещества: стеариновую кислоту 1 мг, магния стеарат 1 мг, желатин 3,5 мг, тальк 2 мг, крахмал картофельный 20,5 мг, лактозы моногидрат 92 мг, целлюлозу микрокристаллическую 10 мг."},{"name":"Действующее вещество","value":"Тофизопам"},{"name":"Способ применения и дозы","value":"Взрослые\u003Cbr\u003EОбычно рекомендуемая доза: 1 - 2 таблетки от 1 до З раз в день (общая суточная доза от 50 до 300 мг).\nПри нерегулярном применении можно принять - 2 таблетки.\nМаксимальная доза составляет 300 мг.\nПостепенное повышение дозы обычно не требуется лечение можно начинать с необходимой дозы, т.к. препарат хорошо переносим и во время его приема обычно не наблюдается уменьшение активности и психического бодрствования.\u003Cbr\u003EДети и подростки в возрасте до 18 лет\u003Cbr\u003EПрименение у детей и подростков до 18 лет противопоказано. Отсутствует достаточный опыт применения препарата у детей и подростков до 18 лет.\u003Cbr\u003EОсобые группы пациентов\u003Cbr\u003EИнформация об особых группах пациентов отсутствует. Клинических исследований, изучающих эффективность и безопасность препарата Грандаксин таблетки 50 мг (тофизопам) у пожилых, у пациентов с почечной и печеночной недостаточностью не проводилось."},{"name":"Побочные действия","value":"Нежелательные реакции приводятся ниже по классам систем органов и частоте: очень часто ( ≥ 1/10), часто ( ≥ 1/100 - \u003C 1/10), нечасто ( ≥ 1/1000 - ≤ 1/100), редко ( ≥ 1/10000 - ≤ 1/1000), очень редко (≤ 1/10 000) или наблюдаемые с неизвестной частотой (невозможно оценить на основании имеющихся данных).\nВ каждой частотной категории нежелательные реакции приводятся в порядке уменьшения их тяжести.\nДля большинства нежелательных реакций отсутствуют данные для определения их частоты.\u003Cbr\u003EНарушения психики:\u003Cbr\u003EОчень редко: спутанное сознание;\u003Cbr\u003EЧастота неизвестна: возбуждение, повышенная раздражимость, ощущение психического напряжения, ухудшение аппетита.\u003Cbr\u003EНарушения со стороны нервной системы:\u003Cbr\u003EБессонница, очень редко препарат может провоцировать судорожные припадки у пациентов с эпилепсией.\u003Cbr\u003EНарушения со стороны дыхательной системы, органов грудной метки и средостения:\u003Cbr\u003EУгнетение дыхания\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта:\u003Cbr\u003EТошнота, рвота, запор, метеоризм, сухость во рту\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей:\u003Cbr\u003EОчень редко: холестатическая желтуха\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей:\u003Cbr\u003EЭкзантема, скарлатиноподобная экзантема\u003Cbr\u003EНарушения со стороны костном, мышечном и соединительной ткани:\u003Cbr\u003EНапряжение мышц, боль в мышцах.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения:\u003Cbr\u003EГоловная боль, кожный зуд."},{"name":"Фармакологическое действие","value":"Тофизопам является мягким анксиолитиком с кратковременным действием и широким терапевтическим индексом. Точный механизм действия неизвестен. Как по химической структуре, так и по клинико-фармакологическому эффекту тофизопам отличается от других 1 ,4-бензодиазепинов.\nПрепарат эффективен при лечении тревожных расстройств, в том числе сопровождающихся вегетативными проявлениями, усталостью, апатией. В отличие от других бензодиазепинов, тофизопам не обладает седативным, снотворным, миорелаксирующим и противосудорожным действием. Препарат не оказывает неблагоприятного действия на память, психомоторную и когнитивную функцию, но обладает умеренной стимулирующей активностью.\nВследствие отсутствия миорелаксирующего эффекта препарат может применяться и у пациентов с миопатией, миастенией и нейрогенными атрофиями мышц, при которых применение миорелаксантов противопоказано или нежелательно. При длительном применении тофизопам не вызывает развитие физической или психической зависимости."},{"name":"Фармакологическая группа","value":"анксиолитическое средство (транквилизатор)"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"Хранить препарат при температуре от 15 до 25 °С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы: эффекты подавления функции центральной нервной системы (ЦНС) проявляются только после приема высоких доз (50 - 120 мг/кг массы тела). Такие дозы могут вызвать рвоту, спутанное сознание, кому, угнетение дыхания и/или эпилептические припадки.\u003Cbr\u003EЛечение: при выраженном подавлении функций ЦНС не рекомендуется вызывать рвоту. Промывание желудка. Введение активированного угля и применение слабительных помогает уменьшить всасывание препарата. Следует постоянно следить за основными физиологическими параметрами и применять соответствующую симптоматическую терапию. При угнетении дыхания следует проводить искусственную вентиляцию легких. Введение стимуляторов ЦНС не рекомендуется. Гипотензию лучше всего устранять в/в введением жидкостей и переводом пациента в положение Тренделенбурга. Если эти меры не восстанавливают уровень артериального давления (АД), можно ввести дофамин или норадреналин. Диализ и вызванный диурез не эффективны.\nВ качестве антагониста можно ввести флумазенил, однако, его применение при передозировке тофизопамом клинически не протестировано."},{"name":"Применение при беременности и кормлении грудью","value":"Беременность\u003Cbr\u003EТофизопам проникает через плацентарный барьер. Применение этого препарата при беременности противопоказано.\u003Cbr\u003EПериод грудного вскармливания\u003Cbr\u003EПрепарат выделяется в грудное молоко, поэтому не рекомендуется его применять во время грудного вскармливания."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В период применения препарата запрещено вождение транспортных средств или работа со сложными механизмами, требующими повышенной концентрации внимания."},{"name":"Особые указания","value":"Необходима особая осторожность при лечении пациентов с компенсированной хронической дыхательной недостаточностью или ранее перенесших острую дыхательную недостаточность.\u003Cbr\u003EОсторожность необходима при лечении пожилых пациентов и лиц с психической деградацией, а также имеющих нарушения функции почек и/или печени, т.к. у них чаще, чем у других пациентов, наблюдаются нежелательные реакции препарата.\u003Cbr\u003EПри сочетании препарата Грандаксин с препаратами, подавляющими функцию ЦНС (антидепрессанты, седативные, снотворные, опиоидные аналгетики, средства общей анестезии), антигистаминными препаратами, антипсихотическими, алкоголем возможно усиление взаимных эффектов.\u003Cbr\u003EНе рекомендуется применять препарат при хроническом психозе, фобии или навязчивых состояниях. При уменьшении торможения возрастает риск суицидальных попыток и агрессивного поведения. Поэтому Грандаксин не рекомендуется в качестве монотерапии депрессии или депрессии, сопровождающейся с тревогой.\u003Cbr\u003EНеобходима осторожность при лечении пациентов с расстройствами личности (психопатии).\u003Cbr\u003EПрепарат следует применять с повышенной осторожностью при органических поражениях головного мозга (например, при атеросклерозе).\u003Cbr\u003EУ пациентов с эпилепсией Грандаксин может провоцировать судорожные припадки.\u003Cbr\u003EНе рекомендуется применять этот препарат пациентам с закрытоугольной глаукомой.\u003Cbr\u003EРиск при совместном применении с опиоидами\u003Cbr\u003EСовместное применение препарата Грандаксин с опиоидами повышает риск седации, угнетения дыхания, комы и смертельного исхода. В связи с повышенным риском совместное применение седативных препаратов возможно лишь у пациентов, для которых невозможно применение альтернативных методов лечения. Если принято решение об одновременном назначении препарата Грандаксин с другими седативными лекарственными средствами, следует использовать самые низкие эффективные дозы, а продолжительность лечения должна быть как можно короче. Таким пациентам необходим тщательный контроль симптомов угнетения дыхания и седации. В связи с этим настоятельно рекомендуется ознакомить пациентов и ухаживающих за ними лиц (при наличии таковых) о симптомах угнетения дыхания и седации.\u003Cbr\u003EПрепарат Грандаксин содержит лактозу\u003Cbr\u003EКаждая таблетка Грандаксин содержит 92 мг лактозы моногидрата. Это следует учитывать пациентам, страдающим редкими наследственными заболеваниями, в том числе непереносимостью галактозы, полной лактазной недостаточностью и мальабсорбцией глюкозы/галактозы.\u003Cbr\u003EС осторожностью:\u003Cbr\u003EНе декомпенсированная хроническая дыхательная недостаточность, острая дыхательная недостаточность в анамнезе, закрытоугольная глаукома, эпилепсия, органические поражения головного мозга (например, атеросклероз). Пожилые пациенты и пациенты с нарушением функции печени или почек. Совместное применение с опиоидами."},{"name":"Взаимодействие","value":"Концентрация в плазме крови препаратов, которые метаболизируются изоферментом СYРЗА4, может увеличиться при одновременном приеме с тофизопамом, поэтому одновременное применение такролимуса, сиролимуса, циклоспорина и тофизопама противопоказано.\u003Cbr\u003EПрименение тофизопама с препаратами, оказывающими угнетающее действие на ЦНС (анальгетики, средства общей анестезии, антидепрессанты, седативные, снотворные,),\nН1- гистаминовых рецепторов блокаторами, антипсихотическими, усиливает их эффекты (например, седативный эффект или угнетение дыхания).\u003Cbr\u003EОпиоиды. Совместное применение лекарственных средств с седативным действием, таких как бензодиазепины или подобные им препараты, такие как Грандаксин, с опиодами повышает риск седации, угнетения дыхания, комы и смертельного исхода в связи с аддитивным угнетающим эффектом этих препаратов на ЦНС. Дозы и продолжительность совместного применения таких препаратов должны быть ограничены\u003Cbr\u003EИндукторы печеночных ферментов (алкоголь, никотин, барбитураты, противоэпилептические средства) могут усилить метаболизм тофизопама, что может привести к снижению его концентрации в плазме крови и ослаблению терапевтического эффекта.\u003Cbr\u003EНекоторые противогрибковые препараты (кетоконазол, итраконазол) могут замедлить печеночный метаболизм тофизопама, что приводит к увеличению его концентрации в плазме крови.\u003Cbr\u003EНекоторые гипотензивные препараты (клонидин, блокаторы «медленных» кальциевых каналов) могут усилить эффекты тофизопама. β-адреноблокаторы могут замедлить метаболизм препарата, однако этот эффект не имеет клинического значения.\u003Cbr\u003EДигоксин: тофизопам может повысить концентрацию дигоксина в плазме крови.\u003Cbr\u003EВарфарин: бензодиазепины могут повлиять на антикоагулянтный эффект варфарина. Дисульфирам: длительное применение дисульфирама может угнетать метаболизм тофизопама.\u003Cbr\u003EАнтацидные средства по-разному влияют на всасывание тофизопама. Циметидин и омепразол угнетают метаболизм тофизопама.\u003Cbr\u003EПероральные контрацептивные средства могут снижать интенсивность метаболизма тофизопама.\u003Cbr\u003EАлкоголь: тофизопам ослабляет угнетающее действие алкоголя на перцепцию."},{"name":"Регистрационный номер","value":"ЛП-№(000172)-(РГ-RU)"},{"name":"Дата государственной регистрации","value":"24.03.2021"},{"name":"Владелец регистрационного удостоверения","value":"Egis Pharmaceuticals"},{"name":"Изготовитель","value":"Фармацевтический завод ЭГИС"},{"name":"Фасовщик","value":"Фармацевтический завод ЭГИС"},{"name":"Страна бренда","value":"Венгрия"},{"name":"Страна-производитель","value":"Венгрия"},{"name":"Название препарата","value":"Грандаксин"},{"name":"Срок годности","value":"60 мес."}]}],"transitionId":"tr_12303499848986180444"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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575 ₽

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  • Гинкго Билоба Эвалар таб., 0.5 г, 100 шт., 1 уп.
    ВАМ–20 %
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    Гинкго Билоба Эвалар таб., 0.5 г, 100 шт., 1 уп.

    Рейтинг товара: 4.8 из 5
    на основе 342 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 1 170 ₽ вместо 1 182
    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Билоба Эвалар таб., 0.5 г, 100 шт., 1 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  • GLS Триптофан капс., 500 мг, 0.25 г, 90 шт.
    –21 %
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    GLS Триптофан капс., 500 мг, 0.25 г, 90 шт.

    Рейтинг товара: 4.8 из 5
    на основе 20 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 503 ₽ вместо 508
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Триптофан капс., 500 мг, 0.25 г, 90 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  • 5-HTP капс., 50 мг, 0.44 г, 30 шт., 1 уп.
    ВАМ–63 %
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    5-HTP капс., 50 мг, 0.44 г, 30 шт., 1 уп.

    Рейтинг товара: 4.7 из 5
    на основе 88 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 577 ₽ вместо 595
    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капс., 50 мг, 0.44 г, 30 шт., 1 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  • Сироп зайчонок успокаивающий д/детей лет (Страна Здравландия), 100 мл, 1 шт., 3 уп.
    –30 %
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    Сироп зайчонок успокаивающий д/детей лет (Страна Здравландия), 100 мл, 1 шт., 3 уп.

    Рейтинг товара: 4.7 из 5
    на основе 85 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 2 286 ₽ вместо 2 332
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  • Сонные+ таб., 30 шт., 1 уп.
    –31 %
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    Сонные+ таб., 30 шт., 1 уп.

    Рейтинг товара: 4.1 из 5
    на основе 149 оценок
    Цена 275 ₽ вместо 399
    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  • Формула Спокойствия Триптофан капс., 15 шт.
    –1 %
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    Формула Спокойствия Триптофан капс., 15 шт.

    Рейтинг товара: 4.6 из 5
    на основе 29 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 452 ₽ вместо 457
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  • Релаксозан День таб., 20 шт.
    –1 %
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    Релаксозан День таб., 20 шт.

    Рейтинг товара: 4 из 5
    на основе 3 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 438 ₽ вместо 442
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  • Ноотроп капс., 52 г, 48 шт., 1 уп.
    –2 %
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    Ноотроп капс., 52 г, 48 шт., 1 уп.

    Рейтинг товара: 4.7 из 5
    на основе 9 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 585 ₽ вместо 597
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  • Антистресс-В таб., 50 шт., 1 уп.
    –34 %
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    Антистресс-В таб., 50 шт., 1 уп.

    Рейтинг товара: 4.6 из 5
    на основе 28 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 259 ₽ вместо 262
    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таб., 50 шт., 1 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Инструкция

Показания к применению

Лечение психических (невротических) и психосоматических расстройств, сопровождающихся эмоциональным напряжением, тревогой, вегетативными расстройствами, апатией, усталостью и подавленным настроением. Алкогольный абстинентный синдром.

Противопоказания

Повышенная чувствительность к тофизопаму, другим производным группы бензодиазепина, а также другим компонентам препарата;
детский возраст до 18 лет;
беременность;
период грудного вскармливания;
состояния, сопровождающиеся выраженным психомоторным возбуждением, агрессией или выраженной депрессией;
декомпенсированная дыхательная недостаточность;
синдром обструктивного апноэ;
кома;
одновременное применение с такролимусом, сиролимусом, циклоспорином;
дефицит лактазы, непереносимость лактозы, глюкозо-галактозная мальабсорбция (препарат содержит лактозы моногидрат).

Способ применения и дозы

Взрослые
Обычно рекомендуемая доза: 1 - 2 таблетки от 1 до З раз в день (общая суточная доза от 50 до 300 мг). При нерегулярном применении можно принять - 2 таблетки. Максимальная доза составляет 300 мг. Постепенное повышение дозы обычно не требуется лечение можно начинать с необходимой дозы, т.к. препарат хорошо переносим и во время его приема обычно не наблюдается уменьшение активности и психического бодрствования.
Дети и подростки в возрасте до 18 лет
Применение у детей и подростков до 18 лет противопоказано. Отсутствует достаточный опыт применения препарата у детей и подростков до 18 лет.
Особые группы пациентов
Информация об особых группах пациентов отсутствует. Клинических исследований, изучающих эффективность и безопасность препарата Грандаксин таблетки 50 мг (тофизопам) у пожилых, у пациентов с почечной и печеночной недостаточностью не проводилось.
Полная инструкция
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Грандаксин таб.
Грандаксин таб., 50 мг, 20 шт.
4.7
(17)
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5 вопросов
Инструкция

575 ₽

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4.7
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У продавца:17 оценок·1 отзыв
У всех продавцов:290 оценок·103 отзыва
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user avatar
Месяц назад • Татьяна Л. • Куплен на Маркете
Достоинства: быстро пришёл, по невысокой цене, помог
Недостатки: нет
Комментарий: спасибо.
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Рекомендуем

  • Сирдалуд таб., 2 мг, 30 шт.
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    Сирдалуд таб., 2 мг, 30 шт.

    Цена 173 ₽ вместо 199
  • Мидокалм таб. п/о плен., 150 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1422663416_1/content/content/gallery":{"title":"Мидокалм таб. п/о плен., 150 мг, 30 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/4441046/img_id8907723315782039268.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4441046/img_id8907723315782039268.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4441046/img_id8907723315782039268.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4441046/img_id8907723315782039268.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4441046/img_id8907723315782039268.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4441046/img_id8907723315782039268.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/5344223/img_id2253265240362406450.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5344223/img_id2253265240362406450.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5344223/img_id2253265240362406450.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5344223/img_id2253265240362406450.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5344223/img_id2253265240362406450.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5344223/img_id2253265240362406450.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4343092/img_id4516567246169985452.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4343092/img_id4516567246169985452.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4343092/img_id4516567246169985452.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4343092/img_id4516567246169985452.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4343092/img_id4516567246169985452.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4343092/img_id4516567246169985452.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQyLHZh8yjitp1EhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIVCPi9sKYFEPql9lgY/tW2CCDn3MEH","sign":"rJxU6tjWoyAL1lhFAeZ/kaLiZBMq8fBPaeMwHZDiYIQ="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1422663416_1/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1422663416_1/content/content/toggleWishlist":{"skuId":"186487546","productId":1422663416,"offerId":"vyOMkKioKqYnhmJmg4rpHw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQyLHZh8yjitp1EhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIVCPi9sKYFEPql9lgY/tW2CCDn3MEH","sign":"rJxU6tjWoyAL1lhFAeZ/kaLiZBMq8fBPaeMwHZDiYIQ="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1422663416_1/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Мидокалм таб. п/о плен., 150 мг, 30 шт.

    Цена 521 ₽
  • Тадалафил-СЗ таб. п/о плен., 5 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1430912592_2/content/content/toggleWishlist":{"skuId":"663684041","productId":1430912592,"offerId":"4A9cwYL-Xu-3Ij4q1F7-GQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQyLHZh8yjitp1EhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCND8p6oFEMmHvLwCGK7e0Acg7tzBBw==","sign":"goc5tlDOyO4zETFIKFO1yum1bDj83ImUn3pQfayW+6o="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1430912592_2/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Тадалафил-СЗ таб. п/о плен., 5 мг, 30 шт.

    Цена 527 ₽
  • GLS Триптофан капс., 500 мг, 0.25 г, 90 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1395321004_3/content/content/gallery":{"title":"GLS Триптофан капс., 500 мг, 0.25 г, 90 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/5221857/img_id1562047820691514187.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5221857/img_id1562047820691514187.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5221857/img_id1562047820691514187.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5221857/img_id1562047820691514187.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5221857/img_id1562047820691514187.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5221857/img_id1562047820691514187.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/5280162/img_id2265473934415980873.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5280162/img_id2265473934415980873.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5280162/img_id2265473934415980873.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5280162/img_id2265473934415980873.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5280162/img_id2265473934415980873.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5280162/img_id2265473934415980873.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/3861966/img_id2749975756973706356.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/3861966/img_id2749975756973706356.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/3861966/img_id2749975756973706356.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/3861966/img_id2749975756973706356.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/3861966/img_id2749975756973706356.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/3861966/img_id2749975756973706356.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQyLHZh8yjitp1EhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIXCKzRq5kFENDp9/76Ahjo5dYKIO3ZwQc=","sign":"vs/IVRAxtG+dh/vhtvP0H1rXVRSJnFap2/pZrsBBBqM="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1395321004_3/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1395321004_3/content/content/toggleWishlist":{"skuId":"101734806736","productId":1395321004,"offerId":"QEDCSJ4XGXwgfBQ6ahJDpQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQyLHZh8yjitp1EhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIXCKzRq5kFENDp9/76Ahjo5dYKIO3ZwQc=","sign":"vs/IVRAxtG+dh/vhtvP0H1rXVRSJnFap2/pZrsBBBqM="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1395321004_3/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    GLS Триптофан капс., 500 мг, 0.25 г, 90 шт.

    Цена 503 ₽ вместо 635
  • Тербинафин крем, 1%, 15 г, 1 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778172509_4/content/content/gallery":{"title":"Тербинафин крем, 1%, 15 г, 1 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/901948/img_id2505434858379086797.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/901948/img_id2505434858379086797.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/901948/img_id2505434858379086797.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/901948/img_id2505434858379086797.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/901948/img_id2505434858379086797.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/901948/img_id2505434858379086797.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/372220/img_id6468787080094353830.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/372220/img_id6468787080094353830.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/372220/img_id6468787080094353830.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/372220/img_id6468787080094353830.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/372220/img_id6468787080094353830.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/372220/img_id6468787080094353830.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQyLHZh8yjitp1EhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIVCN2E888GEM3H8lgY4tzQByDh2cEH","sign":"P20wmgP1w4XOiReAAHo/RXp22xZu2WGv8CxoAqM3x6M="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778172509_4/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778172509_4/content/content/toggleWishlist":{"skuId":"186426317","productId":1778172509,"offerId":"mrIf_QBYVgDHPb47RI8xeg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQyLHZh8yjitp1EhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIVCN2E888GEM3H8lgY4tzQByDh2cEH","sign":"P20wmgP1w4XOiReAAHo/RXp22xZu2WGv8CxoAqM3x6M="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778172509_4/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Тербинафин крем, 1%, 15 г, 1 шт.

    Цена 79 ₽ вместо 80
  • 5-HTP капс., 50 мг, 0.44 г, 30 шт., 1 уп.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1774398206_5/content/content/gallery":{"title":"5-HTP капс., 50 мг, 0.44 г, 30 шт., 1 уп.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/7979270/img_id2925668237767584805.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/7979270/img_id2925668237767584805.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/7979270/img_id2925668237767584805.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/7979270/img_id2925668237767584805.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/7979270/img_id2925668237767584805.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/7979270/img_id2925668237767584805.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/7519991/img_id8431974542747931695.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/7519991/img_id8431974542747931695.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/7519991/img_id8431974542747931695.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/7519991/img_id8431974542747931695.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/7519991/img_id8431974542747931695.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/7519991/img_id8431974542747931695.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQyLHZh8yjitp1EhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIXCP7VjM4GEI6HsbD7AhjxybYEIO3ZwQc=","sign":"9H1lWbTsHFK7gVEpHEIJeKbNeI6465njpu3dft+z5N0="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1774398206_5/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1774398206_5/content/content/toggleWishlist":{"skuId":"101838504846","productId":1774398206,"offerId":"OqUca93cG3lIzI3av8SMsw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQyLHZh8yjitp1EhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIXCP7VjM4GEI6HsbD7AhjxybYEIO3ZwQc=","sign":"9H1lWbTsHFK7gVEpHEIJeKbNeI6465njpu3dft+z5N0="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1774398206_5/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    5-HTP капс., 50 мг, 0.44 г, 30 шт., 1 уп.

    Цена 577 ₽ вместо 1 546
  • Табекс таб. п/о плен., 1.5 мг, 100 шт.
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    Табекс таб. п/о плен., 1.5 мг, 100 шт.

    Цена 1 480 ₽ вместо 1 495
  • Формула Спокойствия Триптофан капс., 15 шт.
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    Формула Спокойствия Триптофан капс., 15 шт.

    Цена 452 ₽ вместо 457
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    Реклама
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  • Релаксозан День таб., 20 шт.
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    Релаксозан День таб., 20 шт.

    Цена 438 ₽ вместо 442
  • Сонные+ таб., 30 шт., 1 уп.
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    Сонные+ таб., 30 шт., 1 уп.

    Цена 275 ₽ вместо 399
  • Эвалар Чай Эвалар БИО при повышенном содержании мочевой кислоты, 20 фильтр-пакетов
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    Эвалар Чай Эвалар БИО при повышенном содержании мочевой кислоты, 20 фильтр-пакетов

    Цена 194 ₽ вместо 224
  • Силденафил-СЗ таб. п/о плен., 100 мг, 10 шт.
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    Силденафил-СЗ таб. п/о плен., 100 мг, 10 шт.

    Цена 314 ₽
  • БиоГая Пробиотик капли детск. фл., 5 мл, 1 уп.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:997279548_13/content/content/gallery":{"title":"БиоГая Пробиотик капли детск. фл., 5 мл, 1 уп.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/5131700/img_id5468924246027050142.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5131700/img_id5468924246027050142.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5131700/img_id5468924246027050142.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5131700/img_id5468924246027050142.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5131700/img_id5468924246027050142.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5131700/img_id5468924246027050142.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4408567/img_id147222889702037708.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4408567/img_id147222889702037708.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4408567/img_id147222889702037708.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4408567/img_id147222889702037708.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4408567/img_id147222889702037708.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4408567/img_id147222889702037708.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQyLHZh8yjitp1EhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIXCLyOxdsDEPTRh9H5Ahj03/kHINrZwQc=","sign":"r/BbyuyxdWVioFhsgTlNcRpPI33zIGw+pz0ccHbYszU="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:997279548_13/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:997279548_13/content/content/toggleWishlist":{"skuId":"101370161396","productId":997279548,"offerId":"DNTgLfhb2SFZHNJpMz1ccg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQyLHZh8yjitp1EhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIXCLyOxdsDEPTRh9H5Ahj03/kHINrZwQc=","sign":"r/BbyuyxdWVioFhsgTlNcRpPI33zIGw+pz0ccHbYszU="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:997279548_13/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    БиоГая Пробиотик капли детск. фл., 5 мл, 1 уп.

    Цена 1 752 ₽ вместо 3 500
  • Ноотроп капс., 52 г, 48 шт., 1 уп.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778172878_14/content/content/gallery":{"title":"Ноотроп капс., 52 г, 48 шт., 1 уп.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/4377400/img_id5088944771564235668.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4377400/img_id5088944771564235668.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4377400/img_id5088944771564235668.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4377400/img_id5088944771564235668.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4377400/img_id5088944771564235668.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4377400/img_id5088944771564235668.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/5229821/img_id6335748772423007962.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5229821/img_id6335748772423007962.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5229821/img_id6335748772423007962.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5229821/img_id6335748772423007962.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5229821/img_id6335748772423007962.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5229821/img_id6335748772423007962.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/5218923/img_id7139891342302725327.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5218923/img_id7139891342302725327.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5218923/img_id7139891342302725327.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5218923/img_id7139891342302725327.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5218923/img_id7139891342302725327.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5218923/img_id7139891342302725327.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4902598/img_id3488766170587726625.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4902598/img_id3488766170587726625.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4902598/img_id3488766170587726625.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4902598/img_id3488766170587726625.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4902598/img_id3488766170587726625.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4902598/img_id3488766170587726625.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQyLHZh8yjitp1EhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIVCM6H888GEMnX0GwY2PrUByDt2cEH","sign":"foSKUcCJWlp1QMpeq3zBPgpXCgfBcqtNrYDsXLQBlaI="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778172878_14/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
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    Ноотроп капс., 52 г, 48 шт., 1 уп.

    Цена 585 ₽ вместо 597
  • Антистресс-В таб., 50 шт., 1 уп.
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    Антистресс-В таб., 50 шт., 1 уп.

    Цена 259 ₽ вместо 393
  • Дипроспан сусп. д/ин., 2мг+5мг/мл, 1 мл, 1 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1436732420_16/content/content/gallery":{"title":"Дипроспан сусп. д/ин., 2мг+5мг/мл, 1 мл, 1 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/1081556/img_id4482846985251727652.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/1081556/img_id4482846985251727652.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/1081556/img_id4482846985251727652.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/1081556/img_id4482846985251727652.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/1081556/img_id4482846985251727652.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/1081556/img_id4482846985251727652.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/1349652/img_id1857878051316176375.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/1349652/img_id1857878051316176375.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/1349652/img_id1857878051316176375.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/1349652/img_id1857878051316176375.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/1349652/img_id1857878051316176375.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/1349652/img_id1857878051316176375.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQyLHZh8yjitp1EhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIVCISYi60FEMbO3mwYi9TQByDz3MEH","sign":"vUUKE4Teht3mLVYUkK8BQJqRYE6BwumpkFWDQ/wiySA="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1436732420_16/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
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    Дипроспан сусп. д/ин., 2мг+5мг/мл, 1 мл, 1 шт.

    Цена 796 ₽
  • Ново-Сед капс., 10 мл, 10 г, 30 шт., нейтральный, 1 уп.
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    Ново-Сед капс., 10 мл, 10 г, 30 шт., нейтральный, 1 уп.

    Цена 333 ₽ вместо 407
  • Гинкго Билоба Эвалар таб., 0.5 г, 40 шт., 1 уп.
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    Гинкго Билоба Эвалар таб., 0.5 г, 40 шт., 1 уп.

    Цена 428 ₽ вместо 432
  • Лимфомиозот капли д/вн. приема, 30 мл
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    Лимфомиозот капли д/вн. приема, 30 мл

    Цена 910 ₽ вместо 1 081
  • Сироп зайчонок успокаивающий д/детей лет (Страна Здравландия), 100 мл, 115 г, 1 шт., 1 уп.
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    Сироп зайчонок успокаивающий д/детей лет (Страна Здравландия), 100 мл, 115 г, 1 шт., 1 уп.

    Цена 247 ₽ вместо 249
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    Реклама
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  • ЛимфоТранзит концентрат напитка фл., 100 мл
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    ЛимфоТранзит концентрат напитка фл., 100 мл

    Цена 361 ₽ вместо 365
  • Argitos Коллоидное серебро спрей д/мест. прим. фл., 30 мл, 40 г, нейтральный
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    Argitos Коллоидное серебро спрей д/мест. прим. фл., 30 мл, 40 г, нейтральный

    Цена 365 ₽ вместо 395
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