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Имодиум Экспресс таб.-лиоф., 2 мг, 6 шт.

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5.0
(71)
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Количество штук в упаковке, шт.: 6

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Коротко о товаре

Артикул Маркета
3124084614
Тип препарата
Назначение
Действующее вещество
Возраст
от 6 лет
Инструкция
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В качестве вспомогательного лекарственного средства при диарее инфекционного генеза. Регуляция стула у пациентов с илеостомой."},{"name":"Противопоказания","value":"Имодиум Экспресс таблетки-лиофилизат не следует применять у детей в возрасте до 6 лет.\u003Cbr\u003EИмодиум Экспресс противопоказан пациентам с повышенной чувствительностью к лоперамиду и/или любому из компонентов препарата, а также в первом триместре беременности.\u003Cbr\u003EИмодиум Экспресс не рекомендуется принимать в период грудного вскармливания.\u003Cbr\u003EИмодиум Экспресс таблетки-лиофилизат противопоказаны больным фенилкетонурией.\u003Cbr\u003EИмодиум Экспресс нельзя применять в качестве основной терапии:\u003Cbr\u003E-\tу пациентов с острой дизентерией, которая характеризуется стулом с примесью крови и высокой температурой;\u003Cbr\u003E-у пациентов с язвенным колитом в стадии обострения;\u003Cbr\u003E-\tу пациентов с бактериальным энтероколитом, вызванным патогенными микроорганизмами, в том числе Salmonella, Shigella и Campylobacter; у пациентов с псевдомембранозным колитом, связанным с терапией антибиотиками широкого спектра действия.\u003Cbr\u003EИмодиум Экспресс не следует применять в случаях, когда замедление перистальтики нежелательно из-за возможного риска развития серьезных осложнений, в том числе кишечной непроходимости, мегаколона и токсического мегаколона. Имодиум Экспресс необходимо немедленно отменить при появлении запора, вздутии живота или кишечной непроходимости.\u003Cbr\u003E"},{"name":"Состав","value":"Состав (на одну таблетку):\u003Cbr\u003EДействующее вещество: лоперамида гидрохлорид 2 мг.\u003Cbr\u003EВспомогательные вещества: желатин, маннитол, аспартам, ароматизатор мятный, натрия гидрокарбонат.\u003Cbr\u003E"},{"name":"Действующее вещество","value":"Лоперамид","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["27144131:28710252"]}}},{"name":"Способ применения и дозы","value":"Внутрь. Таблетку кладут на язык, в течение нескольких секунд она растворяется, после чего ее проглатывают со слюной, не запивая водой.\u003Cbr\u003EВзрослые и Дети старше 6 лет:\u003Cbr\u003EОстрая диарея: начальная доза — 2 таблетки (4 мг) для взрослых и 1 таблетка (2 мг) для детей, далее по 1 таблетке (2 мг) после каждого акта дефекации в случае жидкого стула.\u003Cbr\u003EХроническая диарея: начальная доза — 2 таблетки (4 мг) в сутки для взрослых и 1 таблетка (2 мг) для детей; далее начальная доза должна быть откорректирована таким образом, чтобы частота нормального стула составляла 1—2 раза в сутки, что обычно достигается при поддерживающей дозе от 1 до 6 таблеток (2—12 мг) в сутки.\u003Cbr\u003EМаксимальная суточная доза не должна превышать 6 таблеток (12 мг); максимальная суточная доза у детей рассчитывается, исходя из массы тела (3 таблетки на 20 кг массы тела ребенка), но не должна превышать 6 таблеток (12 мг).\u003Cbr\u003EПри нормализации стула или при отсутствии стула более 12 ч препарат отменяют.\u003Cbr\u003EПрименение у детей\u003Cbr\u003EНе применять Имодиум Экспресс у детей до 6 лет.\u003Cbr\u003EПрименение у пожилых пациентов\u003Cbr\u003E При лечении пожилых пациентов корректировка дозы не требуется.\u003Cbr\u003E Применение у пациентов с нарушениями функции почек\u003Cbr\u003EПри лечении пациентов с нарушениями функции почек корректировка дозы не требуется.\u003Cbr\u003EПрименение у пациентов с нарушениями функции печени\u003Cbr\u003EХотя фармакокинетические данные у пациентов с печеночной недостаточностью отсутствуют, у таких больных Имодиум Экспресс следует применять с осторожностью вследствие замедленного пресистемного метаболизма.\u003Cbr\u003EУКАЗАНИЯ ПО ПРИМЕНЕНИЮ\u003Cbr\u003EПоскольку таблетки-лиофилизат довольно хрупкие, во избежание повреждения их не следует продавливать сквозь фольгу.\u003Cbr\u003EДля того чтобы достать таблетку из блистера необходимо выполнить с следующие действия:\u003Cbr\u003E-\tвозьмите фольгу за край и полностью снимите ее с ячейки, в которой находится таблетка;\u003Cbr\u003E-\tосторожно надавите снизу и извлеките таблетку из упаковки.\u003Cbr\u003E"},{"name":"Побочные действия","value":"По данным клинических исследований\u003Cbr\u003EНежелательные реакции, наблюдавшиеся у ⩾ 1 % пациентов, принимавших Имодиум Экспресс при острой диарее: головная боль, запор, метеоризм, тошнота, рвота.\u003Cbr\u003EНежелательные реакции, наблюдавшиеся у ⩾ 1 % пациентов, принимавших Имодиум Экспресс при хронической диарее: головокружение, метеоризм, запор, тошнота.\u003Cbr\u003EПо данным постмаркетинговых исследований (спонтанных сообщений о нежелательных реакциях и клинических или эпидемиологических исследований)\u003Cbr\u003EНижеперечисленные нежелательные реакции классифицировали следующим образом: очень часто (⩾ 10 %), часто ⩾ 1 %, но \u003C 10 %), нечасто (\u003E0,1 %, но \u003C 1 %), редко (⩾ 0,01 %, но \u003C 0,1 %) и очень редко (\u003C0,01 %, включая единичные сообщения).\u003Cbr\u003EНарушения со\tстороны иммунной системы.\tРедко:\tреакции гиперчувствительности,\tанафилактические\tреакции,\tвключая анафилактический шок, и анафилактоидные реакции.\u003Cbr\u003EНарушения со стороны нервной системы. Часто: головная боль, головокружение. Нечасто: сонливость. Редко: нарушение координации, угнетение сознания, гипертонус, потеря сознания, ступор.\u003Cbr\u003EНарушения со стороны органа зрения. Редко: миоз.\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта. Часто: запор, тошнота, метеоризм. Нечасто: боль в животе, дискомфорт в области живота, сухость во рту, боль в эпигастральной области, рвота, диспепсия. Редко: вздутие живота, кишечная непроходимость (в том числе, паралитическая кишечная непроходимость), мегаколон (в том числе, токсический мегаколон), глоссалгия.\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей. Нечасто: кожная сыпь. Редко: ангионевротический отек, кожный зуд, крапивница, буллезная сыпь, включая синдром Стивенса-Джонсона, токсический эпидермальный некролиз и многоформную эритему.\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей. Редко: задержка мочи.\u003Cbr\u003EОбщие расстройства. Редко: утомляемость.\u003Cbr\u003E"},{"name":"Фармакологическое действие","value":"Лоперамид, связываясь с опиоидными рецепторами в стенке кишечника, подавляет высвобождение ацетилхолина и простагландинов, замедляя таким образом перистальтику и увеличивая время прохождения содержимого по кишечнику. Повышает тонус анального сфинктера, уменьшая тем самым недержание каловых масс и позывы к дефекации.Имодиум® Экспресс следует применять с осторожностью у пациентов с нарушениями функции печени вследствие замедленного пресистемного метаболизма."},{"name":"Фармакологическая группа","value":"противодиарейные средства"},{"name":"Форма выпуска","value":"таблетки лиофилизированные"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 6 лет"},{"name":"Условия хранения","value":"Хранить при температуре от 15 до 30 °С. Хранить в недоступном для детей месте. Хранить в оригинальной упаковке."},{"name":"Передозировка","value":"Симптомы\u003Cbr\u003EПри передозировке (в том числе, при относительной передозировке вследствие нарушения функции печени) могут появиться задержка мочеиспускания, паралитическая кишечная непроходимость, запор, признаки угнетения центральной нервной системы (ЦНС) (угнетение дыхания, обструкция дыхательных путей, рвота с нарушением сознания, ступор, нарушение координации, сонливость, миоз, гипертонус мышц). Дети и пациенты с нарушением функции печени могут быть более чувствительны к влиянию лоперамида на ЦНС, чем взрослые.\u003Cbr\u003EУ лиц, преднамеренно принявших чрезмерную дозу (от 40 мг до 240 мг/сутки) лоперамида гидрохлорида, отмечалось удлинение интервала QT и комплекса QRS и/или серьезные желудочковые аритмии, включая тахикардию по типу «пируэт»; остановка сердца, обморок. Также описывались случаи смертельного исхода при преднамеренной передозировке.\u003Cbr\u003EЗлоупотребление, неправильное применение и/или передозировка высокими дозами лоперамида может привести к клиническому проявлению синдрома\u003Cbr\u003EБругада.\u003Cbr\u003EТерапия\u003Cbr\u003EВ случае передозировки необходимо начать ЭКГ-мониторинг для выявления удлинения интервала QT.\u003Cbr\u003EПри появлении симптомов передозировки в качестве антидота можно использовать налоксон. Поскольку длительность действия лоперамида больше, чем налоксона (1—3 часа), может потребоваться повторное применение налоксона. Поэтому необходимо тщательно наблюдать за состоянием пациента в течение как минимум 48 часов с целью своевременного обнаружения признаков возможного угнетения ЦНС.\u003Cbr\u003EВ связи с тем, что тактика купирования передозировки постоянно изменяется, рекомендуется связаться с токсикологическим центром (при наличии) для получения наиболее актуальных рекомендаций по лечению передозировки.\u003Cbr\u003E"},{"name":"Применение при беременности и кормлении грудью","value":"Имодиум Экспресс не рекомендуется применять во время беременности и в период грудного вскармливания. В случае диареи при беременности или кормлении грудью необходима консультация с лечащим врачом для назначения соответствующего лечения."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В период лечения препаратом Имодиум Экспресс следует воздержаться от управления транспортными средствами и занятий другими потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций, так как препарат может вызывать головокружение и другие побочные эффекты, которые могут влиять на указанные способности."},{"name":"Особые указания","value":"С осторожностью\u003Cbr\u003EИмодиум Экспресс следует применять с осторожностью у пациентов с нарушениями функции печени вследствие замедленного пресистемного метаболизма.\u003Cbr\u003EЛечение диареи препаратом Имодиум Экспресс носит только симптоматический характер. В тех случаях, когда возможно установить причину диареи, необходимо проводить соответствующую терапию.\u003Cbr\u003EУ пациентов с диареей (особенно у детей) может иметь место потеря жидкости и электролитов. В таких случаях необходимо проводить соответствующую заместительную терапию (восполнение жидкости и электролитов).\u003Cbr\u003EИмодиум\tЭкспресс,\tтаблетки-лиофилизат\tсодержат\tисточник фенилаланина. Прием больным фенилкетонурией противопоказан.\u003Cbr\u003EПри отсутствии эффекта после 2 суток лечения необходимо прекратить прием препарата, уточнить диагноз и исключить инфекционный генез диареи.\u003Cbr\u003EПациенты со СПИДом, принимающие Имодиум Экспресс для лечения диареи, должны прекратить прием препарата при первых признаках вздутия живота, а также признаках кишечной непроходимости. Поступали единичные сообщения о запоре с повышенным риском развития токсического мегаколона у пациентов со СПИДом и инфекционным колитом вирусной и бактериальной этиологии, которым проводилась терапия лоперамидом.\u003Cbr\u003EИмодиум Экспресс необходимо применять с осторожностью у пациентов с печеночной недостаточностью, так как это может привести к токсическому воздействию на ЦНС вследствие относительной передозировки.\u003Cbr\u003EЗлоупотребление или неправильное применение лоперамида в качестве заменителя опиоидов описывали у лиц с опиоидной зависимостью.\u003Cbr\u003EСообщалось об удлинении интервала \tи развитии желудочковой аритмии, включая тахикардию по типу «пируэт», в связи с передозировкой лоперамида, в некоторых случаях со смертельным исходом. Имодиум Экспресс не следует использовать в течение длительного периода времени без наблюдения врача, пациенты не должны превышать рекомендуемую дозу и/или рекомендуемую продолжительность лечения.\u003Cbr\u003EЕсли лекарственное средство пришло в негодность или истек срок годности, не выбрасывайте его в сточные воды и на улицу. Поместите лекарственное средство в пакет и положите в мусорный контейнер. Эти меры помогут защитить окружающую среду.\u003Cbr\u003E"},{"name":"Взаимодействие","value":"По данным доклинических исследований лоперамид является субстратом Р-гликопротеина. При одновременном применении лоперамида (однократно в дозе 16 мг) и хинидина или ритонавира, являющихся ингибиторами Р-гликопротеина, концентрация лоперамида в плазме крови увеличилась в 2—3 раза. Клиническое значение описанного фармакокинетического взаимодействия с ингибиторами Р-гликопротеина при применении лоперамида в рекомендованных дозах неизвестно.\u003Cbr\u003EОдновременное применение лоперамида (однократно в дозе 4 мг) и итраконазола, ингибитора изофермента СУР3А4 и Р-гликопротеина, привело к увеличению концентрации лоперамида в плазме крови в 3—4 раза. В этом же исследовании применение ингибитора изофермента СУР2С8 гемфиброзила, привело к увеличению концентрации лоперамида в плазме крови приблизительно в 2 раза. При применении комбинации итраконазола и гемфиброзила пиковая концентрация лоперамида в плазме крови увеличилась в 4 раза, а общая концентрация — в 13 раз. Это повышение не было связано с влиянием на ГАНС, что оценивалось по психомоторным тестам (т. е. субъективной оценке сонливости и тесту замены цифровых символов).\u003Cbr\u003EОдновременное применение лоперамида (однократно в дозе 16 мг) и кетоконазола, ингибитора СУР3А4 и Р-гликопротеина, привело к пятикратному повышению концентрации лоперамида в плазме крови. Это повышение не было связано с увеличением фармакодинамического действия, оцененного по величине зрачка.\u003Cbr\u003EПри одновременном пероральном приеме десмопрессина концентрация десмопрессина в плазме крови увеличилась в З раза, вероятно, из-за замедления моторики желудочно-кишечного тракта.\u003Cbr\u003EОжидается, что препараты со схожими фармакологическими свойствами могут усиливать действие лоперамида, а препараты, увеличивающие скорость прохождения через желудочно-кишечный тракт, могут уменьшать действие лоперамида.\u003Cbr\u003E"},{"name":"Регистрационный номер","value":"П N016140/01"},{"name":"Дата государственной регистрации","value":"24.01.2023"},{"name":"Владелец регистрационного удостоверения","value":"Johnson & Johnson","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["34324371:35649313","7893318:10789460"]}}},{"name":"Изготовитель","value":"Catalent U.K. Swindon Zydis Ltd"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Великобритания"},{"name":"Название препарата","value":"Имодиум","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["17796364:18008542"]}}},{"name":"Срок годности","value":"59 мес."}]}},"fullSpecsGrouped":{"3606815802973253155":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Органы и системы","value":"кишечник, пищеварительная система"},{"name":"Назначение","value":"диарея"},{"name":"Показания к применению","value":"Симптоматическое лечение острой и хронической диареи (генеза: аллергического, эмоционального, лекарственного, лучевого; при изменении режима питания и качественного состава пищи, при нарушении метаболизма и всасывания). В качестве вспомогательного лекарственного средства при диарее инфекционного генеза. Регуляция стула у пациентов с илеостомой."},{"name":"Противопоказания","value":"Имодиум Экспресс таблетки-лиофилизат не следует применять у детей в возрасте до 6 лет.\u003Cbr\u003EИмодиум Экспресс противопоказан пациентам с повышенной чувствительностью к лоперамиду и/или любому из компонентов препарата, а также в первом триместре беременности.\u003Cbr\u003EИмодиум Экспресс не рекомендуется принимать в период грудного вскармливания.\u003Cbr\u003EИмодиум Экспресс таблетки-лиофилизат противопоказаны больным фенилкетонурией.\u003Cbr\u003EИмодиум Экспресс нельзя применять в качестве основной терапии:\u003Cbr\u003E-\tу пациентов с острой дизентерией, которая характеризуется стулом с примесью крови и высокой температурой;\u003Cbr\u003E-у пациентов с язвенным колитом в стадии обострения;\u003Cbr\u003E-\tу пациентов с бактериальным энтероколитом, вызванным патогенными микроорганизмами, в том числе Salmonella, Shigella и Campylobacter; у пациентов с псевдомембранозным колитом, связанным с терапией антибиотиками широкого спектра действия.\u003Cbr\u003EИмодиум Экспресс не следует применять в случаях, когда замедление перистальтики нежелательно из-за возможного риска развития серьезных осложнений, в том числе кишечной непроходимости, мегаколона и токсического мегаколона. Имодиум Экспресс необходимо немедленно отменить при появлении запора, вздутии живота или кишечной непроходимости.\u003Cbr\u003E"},{"name":"Состав","value":"Состав (на одну таблетку):\u003Cbr\u003EДействующее вещество: лоперамида гидрохлорид 2 мг.\u003Cbr\u003EВспомогательные вещества: желатин, маннитол, аспартам, ароматизатор мятный, натрия гидрокарбонат.\u003Cbr\u003E"},{"name":"Действующее вещество","value":"Лоперамид"},{"name":"Способ применения и дозы","value":"Внутрь. Таблетку кладут на язык, в течение нескольких секунд она растворяется, после чего ее проглатывают со слюной, не запивая водой.\u003Cbr\u003EВзрослые и Дети старше 6 лет:\u003Cbr\u003EОстрая диарея: начальная доза — 2 таблетки (4 мг) для взрослых и 1 таблетка (2 мг) для детей, далее по 1 таблетке (2 мг) после каждого акта дефекации в случае жидкого стула.\u003Cbr\u003EХроническая диарея: начальная доза — 2 таблетки (4 мг) в сутки для взрослых и 1 таблетка (2 мг) для детей; далее начальная доза должна быть откорректирована таким образом, чтобы частота нормального стула составляла 1—2 раза в сутки, что обычно достигается при поддерживающей дозе от 1 до 6 таблеток (2—12 мг) в сутки.\u003Cbr\u003EМаксимальная суточная доза не должна превышать 6 таблеток (12 мг); максимальная суточная доза у детей рассчитывается, исходя из массы тела (3 таблетки на 20 кг массы тела ребенка), но не должна превышать 6 таблеток (12 мг).\u003Cbr\u003EПри нормализации стула или при отсутствии стула более 12 ч препарат отменяют.\u003Cbr\u003EПрименение у детей\u003Cbr\u003EНе применять Имодиум Экспресс у детей до 6 лет.\u003Cbr\u003EПрименение у пожилых пациентов\u003Cbr\u003E При лечении пожилых пациентов корректировка дозы не требуется.\u003Cbr\u003E Применение у пациентов с нарушениями функции почек\u003Cbr\u003EПри лечении пациентов с нарушениями функции почек корректировка дозы не требуется.\u003Cbr\u003EПрименение у пациентов с нарушениями функции печени\u003Cbr\u003EХотя фармакокинетические данные у пациентов с печеночной недостаточностью отсутствуют, у таких больных Имодиум Экспресс следует применять с осторожностью вследствие замедленного пресистемного метаболизма.\u003Cbr\u003EУКАЗАНИЯ ПО ПРИМЕНЕНИЮ\u003Cbr\u003EПоскольку таблетки-лиофилизат довольно хрупкие, во избежание повреждения их не следует продавливать сквозь фольгу.\u003Cbr\u003EДля того чтобы достать таблетку из блистера необходимо выполнить с следующие действия:\u003Cbr\u003E-\tвозьмите фольгу за край и полностью снимите ее с ячейки, в которой находится таблетка;\u003Cbr\u003E-\tосторожно надавите снизу и извлеките таблетку из упаковки.\u003Cbr\u003E"},{"name":"Побочные действия","value":"По данным клинических исследований\u003Cbr\u003EНежелательные реакции, наблюдавшиеся у ⩾ 1 % пациентов, принимавших Имодиум Экспресс при острой диарее: головная боль, запор, метеоризм, тошнота, рвота.\u003Cbr\u003EНежелательные реакции, наблюдавшиеся у ⩾ 1 % пациентов, принимавших Имодиум Экспресс при хронической диарее: головокружение, метеоризм, запор, тошнота.\u003Cbr\u003EПо данным постмаркетинговых исследований (спонтанных сообщений о нежелательных реакциях и клинических или эпидемиологических исследований)\u003Cbr\u003EНижеперечисленные нежелательные реакции классифицировали следующим образом: очень часто (⩾ 10 %), часто ⩾ 1 %, но \u003C 10 %), нечасто (\u003E0,1 %, но \u003C 1 %), редко (⩾ 0,01 %, но \u003C 0,1 %) и очень редко (\u003C0,01 %, включая единичные сообщения).\u003Cbr\u003EНарушения со\tстороны иммунной системы.\tРедко:\tреакции гиперчувствительности,\tанафилактические\tреакции,\tвключая анафилактический шок, и анафилактоидные реакции.\u003Cbr\u003EНарушения со стороны нервной системы. Часто: головная боль, головокружение. Нечасто: сонливость. Редко: нарушение координации, угнетение сознания, гипертонус, потеря сознания, ступор.\u003Cbr\u003EНарушения со стороны органа зрения. Редко: миоз.\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта. Часто: запор, тошнота, метеоризм. Нечасто: боль в животе, дискомфорт в области живота, сухость во рту, боль в эпигастральной области, рвота, диспепсия. Редко: вздутие живота, кишечная непроходимость (в том числе, паралитическая кишечная непроходимость), мегаколон (в том числе, токсический мегаколон), глоссалгия.\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей. Нечасто: кожная сыпь. Редко: ангионевротический отек, кожный зуд, крапивница, буллезная сыпь, включая синдром Стивенса-Джонсона, токсический эпидермальный некролиз и многоформную эритему.\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей. Редко: задержка мочи.\u003Cbr\u003EОбщие расстройства. Редко: утомляемость.\u003Cbr\u003E"},{"name":"Фармакологическое действие","value":"Лоперамид, связываясь с опиоидными рецепторами в стенке кишечника, подавляет высвобождение ацетилхолина и простагландинов, замедляя таким образом перистальтику и увеличивая время прохождения содержимого по кишечнику. Повышает тонус анального сфинктера, уменьшая тем самым недержание каловых масс и позывы к дефекации.Имодиум® Экспресс следует применять с осторожностью у пациентов с нарушениями функции печени вследствие замедленного пресистемного метаболизма."},{"name":"Фармакологическая группа","value":"противодиарейные средства"},{"name":"Форма выпуска","value":"таблетки лиофилизированные"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 6 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"Хранить при температуре от 15 до 30 °С. Хранить в недоступном для детей месте. Хранить в оригинальной упаковке."},{"name":"Передозировка","value":"Симптомы\u003Cbr\u003EПри передозировке (в том числе, при относительной передозировке вследствие нарушения функции печени) могут появиться задержка мочеиспускания, паралитическая кишечная непроходимость, запор, признаки угнетения центральной нервной системы (ЦНС) (угнетение дыхания, обструкция дыхательных путей, рвота с нарушением сознания, ступор, нарушение координации, сонливость, миоз, гипертонус мышц). Дети и пациенты с нарушением функции печени могут быть более чувствительны к влиянию лоперамида на ЦНС, чем взрослые.\u003Cbr\u003EУ лиц, преднамеренно принявших чрезмерную дозу (от 40 мг до 240 мг/сутки) лоперамида гидрохлорида, отмечалось удлинение интервала QT и комплекса QRS и/или серьезные желудочковые аритмии, включая тахикардию по типу «пируэт»; остановка сердца, обморок. Также описывались случаи смертельного исхода при преднамеренной передозировке.\u003Cbr\u003EЗлоупотребление, неправильное применение и/или передозировка высокими дозами лоперамида может привести к клиническому проявлению синдрома\u003Cbr\u003EБругада.\u003Cbr\u003EТерапия\u003Cbr\u003EВ случае передозировки необходимо начать ЭКГ-мониторинг для выявления удлинения интервала QT.\u003Cbr\u003EПри появлении симптомов передозировки в качестве антидота можно использовать налоксон. Поскольку длительность действия лоперамида больше, чем налоксона (1—3 часа), может потребоваться повторное применение налоксона. Поэтому необходимо тщательно наблюдать за состоянием пациента в течение как минимум 48 часов с целью своевременного обнаружения признаков возможного угнетения ЦНС.\u003Cbr\u003EВ связи с тем, что тактика купирования передозировки постоянно изменяется, рекомендуется связаться с токсикологическим центром (при наличии) для получения наиболее актуальных рекомендаций по лечению передозировки.\u003Cbr\u003E"},{"name":"Применение при беременности и кормлении грудью","value":"Имодиум Экспресс не рекомендуется применять во время беременности и в период грудного вскармливания. В случае диареи при беременности или кормлении грудью необходима консультация с лечащим врачом для назначения соответствующего лечения."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В период лечения препаратом Имодиум Экспресс следует воздержаться от управления транспортными средствами и занятий другими потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций, так как препарат может вызывать головокружение и другие побочные эффекты, которые могут влиять на указанные способности."},{"name":"Особые указания","value":"С осторожностью\u003Cbr\u003EИмодиум Экспресс следует применять с осторожностью у пациентов с нарушениями функции печени вследствие замедленного пресистемного метаболизма.\u003Cbr\u003EЛечение диареи препаратом Имодиум Экспресс носит только симптоматический характер. В тех случаях, когда возможно установить причину диареи, необходимо проводить соответствующую терапию.\u003Cbr\u003EУ пациентов с диареей (особенно у детей) может иметь место потеря жидкости и электролитов. В таких случаях необходимо проводить соответствующую заместительную терапию (восполнение жидкости и электролитов).\u003Cbr\u003EИмодиум\tЭкспресс,\tтаблетки-лиофилизат\tсодержат\tисточник фенилаланина. Прием больным фенилкетонурией противопоказан.\u003Cbr\u003EПри отсутствии эффекта после 2 суток лечения необходимо прекратить прием препарата, уточнить диагноз и исключить инфекционный генез диареи.\u003Cbr\u003EПациенты со СПИДом, принимающие Имодиум Экспресс для лечения диареи, должны прекратить прием препарата при первых признаках вздутия живота, а также признаках кишечной непроходимости. Поступали единичные сообщения о запоре с повышенным риском развития токсического мегаколона у пациентов со СПИДом и инфекционным колитом вирусной и бактериальной этиологии, которым проводилась терапия лоперамидом.\u003Cbr\u003EИмодиум Экспресс необходимо применять с осторожностью у пациентов с печеночной недостаточностью, так как это может привести к токсическому воздействию на ЦНС вследствие относительной передозировки.\u003Cbr\u003EЗлоупотребление или неправильное применение лоперамида в качестве заменителя опиоидов описывали у лиц с опиоидной зависимостью.\u003Cbr\u003EСообщалось об удлинении интервала \tи развитии желудочковой аритмии, включая тахикардию по типу «пируэт», в связи с передозировкой лоперамида, в некоторых случаях со смертельным исходом. Имодиум Экспресс не следует использовать в течение длительного периода времени без наблюдения врача, пациенты не должны превышать рекомендуемую дозу и/или рекомендуемую продолжительность лечения.\u003Cbr\u003EЕсли лекарственное средство пришло в негодность или истек срок годности, не выбрасывайте его в сточные воды и на улицу. Поместите лекарственное средство в пакет и положите в мусорный контейнер. Эти меры помогут защитить окружающую среду.\u003Cbr\u003E"},{"name":"Взаимодействие","value":"По данным доклинических исследований лоперамид является субстратом Р-гликопротеина. При одновременном применении лоперамида (однократно в дозе 16 мг) и хинидина или ритонавира, являющихся ингибиторами Р-гликопротеина, концентрация лоперамида в плазме крови увеличилась в 2—3 раза. Клиническое значение описанного фармакокинетического взаимодействия с ингибиторами Р-гликопротеина при применении лоперамида в рекомендованных дозах неизвестно.\u003Cbr\u003EОдновременное применение лоперамида (однократно в дозе 4 мг) и итраконазола, ингибитора изофермента СУР3А4 и Р-гликопротеина, привело к увеличению концентрации лоперамида в плазме крови в 3—4 раза. В этом же исследовании применение ингибитора изофермента СУР2С8 гемфиброзила, привело к увеличению концентрации лоперамида в плазме крови приблизительно в 2 раза. При применении комбинации итраконазола и гемфиброзила пиковая концентрация лоперамида в плазме крови увеличилась в 4 раза, а общая концентрация — в 13 раз. Это повышение не было связано с влиянием на ГАНС, что оценивалось по психомоторным тестам (т. е. субъективной оценке сонливости и тесту замены цифровых символов).\u003Cbr\u003EОдновременное применение лоперамида (однократно в дозе 16 мг) и кетоконазола, ингибитора СУР3А4 и Р-гликопротеина, привело к пятикратному повышению концентрации лоперамида в плазме крови. Это повышение не было связано с увеличением фармакодинамического действия, оцененного по величине зрачка.\u003Cbr\u003EПри одновременном пероральном приеме десмопрессина концентрация десмопрессина в плазме крови увеличилась в З раза, вероятно, из-за замедления моторики желудочно-кишечного тракта.\u003Cbr\u003EОжидается, что препараты со схожими фармакологическими свойствами могут усиливать действие лоперамида, а препараты, увеличивающие скорость прохождения через желудочно-кишечный тракт, могут уменьшать действие лоперамида.\u003Cbr\u003E"},{"name":"Регистрационный номер","value":"П N016140/01"},{"name":"Дата государственной регистрации","value":"24.01.2023"},{"name":"Владелец регистрационного удостоверения","value":"Johnson & Johnson"},{"name":"Изготовитель","value":"Catalent U.K. Swindon Zydis Ltd"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Великобритания"},{"name":"Название препарата","value":"Имодиум"},{"name":"Срок годности","value":"59 мес."}]}],"transitionId":"tr_18275899034443624256"}}}}
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Цена с картой Яндекс Пэй:183 ₽

Скидка: 14%
–14 %
Вместо: 185 ₽213 ₽
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  • Сегодня, курьер магазина • 249 ₽
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Инструкция

Показания к применению

Симптоматическое лечение острой и хронической диареи (генеза: аллергического, эмоционального, лекарственного, лучевого; при изменении режима питания и качественного состава пищи, при нарушении метаболизма и всасывания). В качестве вспомогательного лекарственного средства при диарее инфекционного генеза. Регуляция стула у пациентов с илеостомой.

Противопоказания

Имодиум Экспресс таблетки-лиофилизат не следует применять у детей в возрасте до 6 лет.
Имодиум Экспресс противопоказан пациентам с повышенной чувствительностью к лоперамиду и/или любому из компонентов препарата, а также в первом триместре беременности.
Имодиум Экспресс не рекомендуется принимать в период грудного вскармливания.
Имодиум Экспресс таблетки-лиофилизат противопоказаны больным фенилкетонурией.
Имодиум Экспресс нельзя применять в качестве основной терапии:
- у пациентов с острой дизентерией, которая характеризуется стулом с примесью крови и высокой температурой;
-у пациентов с язвенным колитом в стадии обострения;
- у пациентов с бактериальным энтероколитом, вызванным патогенными микроорганизмами, в том числе Salmonella, Shigella и Campylobacter; у пациентов с псевдомембранозным колитом, связанным с терапией антибиотиками широкого спектра действия.
Имодиум Экспресс не следует применять в случаях, когда замедление перистальтики нежелательно из-за возможного риска развития серьезных осложнений, в том числе кишечной непроходимости, мегаколона и токсического мегаколона. Имодиум Экспресс необходимо немедленно отменить при появлении запора, вздутии живота или кишечной непроходимости.

Способ применения и дозы

Внутрь. Таблетку кладут на язык, в течение нескольких секунд она растворяется, после чего ее проглатывают со слюной, не запивая водой.
Взрослые и Дети старше 6 лет:
Острая диарея: начальная доза — 2 таблетки (4 мг) для взрослых и 1 таблетка (2 мг) для детей, далее по 1 таблетке (2 мг) после каждого акта дефекации в случае жидкого стула.
Хроническая диарея: начальная доза — 2 таблетки (4 мг) в сутки для взрослых и 1 таблетка (2 мг) для детей; далее начальная доза должна быть откорректирована таким образом, чтобы частота нормального стула составляла 1—2 раза в сутки, что обычно достигается при поддерживающей дозе от 1 до 6 таблеток (2—12 мг) в сутки.
Максимальная суточная доза не должна превышать 6 таблеток (12 мг); максимальная суточная доза у детей рассчитывается, исходя из массы тела (3 таблетки на 20 кг массы тела ребенка), но не должна превышать 6 таблеток (12 мг).
При нормализации стула или при отсутствии стула более 12 ч препарат отменяют.
Применение у детей
Не применять Имодиум Экспресс у детей до 6 лет.
Применение у пожилых пациентов
При лечении пожилых пациентов корректировка дозы не требуется.
Применение у пациентов с нарушениями функции почек
При лечении пациентов с нарушениями функции почек корректировка дозы не требуется.
Применение у пациентов с нарушениями функции печени
Хотя фармакокинетические данные у пациентов с печеночной недостаточностью отсутствуют, у таких больных Имодиум Экспресс следует применять с осторожностью вследствие замедленного пресистемного метаболизма.
УКАЗАНИЯ ПО ПРИМЕНЕНИЮ
Поскольку таблетки-лиофилизат довольно хрупкие, во избежание повреждения их не следует продавливать сквозь фольгу.
Для того чтобы достать таблетку из блистера необходимо выполнить с следующие действия:
- возьмите фольгу за край и полностью снимите ее с ячейки, в которой находится таблетка;
- осторожно надавите снизу и извлеките таблетку из упаковки.
Полная инструкция
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Имодиум Экспресс таб.-лиоф.
Имодиум Экспресс таб.-лиоф., 2 мг, 6 шт.
5.0
(71)
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4 вопроса
Инструкция

Цена с картой Яндекс Пэй:183 ₽

Скидка: 14%
–14 %
Вместо: 185 ₽213 ₽
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У продавца:71 оценка·20 отзывов
У всех продавцов:198 оценок·85 отзывов
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user avatar
Неделю назад • Волкова А. • Куплен на Маркете
Достоинства: Быстро действует, удобно применять.
Недостатки: Нет.
Комментарий: Универсальное средство от диареи. Действует быстро, уже через несколько часов. Удобная форма применения, не обязательно запивать водой. Поэтому в качестве средства "скорой помощи" имодиум экспресс просто идеален. Всегда ношу с собой в косметичке, на всякий случай. Но главное, не злоупотреблять им, иначе могут возникнуть побочные действия. Стоит относительно не дорого, продается только в аптеках. Особых условий хранения не требует. К покупке рекомендую!
user avatar
5 дней назад • Виктор Анисимов • Куплен на Маркете
Достоинства: Цена и качество достойные.
Недостатки: Недостатков не обнаружил.
Комментарий: Доставлено в срок. Спасибо большое за Вашу полезную работу.
user avatar
Неделю назад • ксения д. • Куплен на Маркете
Достоинства: Отлично справляется со своими функциями
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    Цена 129 ₽ вместо 167
  • Vitamin D3, 2000 ME, 30 мл, 30 г, 30 шт.
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    Vitamin D3, 2000 ME, 30 мл, 30 г, 30 шт.

    Цена 395 ₽ вместо 806
  • Гематек Стерофундин изотонический р-р д/инф. фл., 500 мл, 10 уп.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:883494022_2/content/content/gallery":{"title":"Гематек Стерофундин изотонический р-р д/инф. фл., 500 мл, 10 уп.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/5279099/img_id9210420955336037572.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5279099/img_id9210420955336037572.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5279099/img_id9210420955336037572.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5279099/img_id9210420955336037572.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5279099/img_id9210420955336037572.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5279099/img_id9210420955336037572.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/5332179/img_id2046991284938407047.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5332179/img_id2046991284938407047.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5332179/img_id2046991284938407047.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5332179/img_id2046991284938407047.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5332179/img_id2046991284938407047.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5332179/img_id2046991284938407047.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQhqDHvrnizMYUEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIXCIaZpKUDEM3T4ZP5AhjM9fYHIJuP1Qc=","sign":"CVPHeUHr/+9nhFiF8ThXSCsT0EVEyhGF3q+CYfkVpZ8="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:883494022_2/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
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    Гематек Стерофундин изотонический р-р д/инф. фл., 500 мл, 10 уп.

    Цена 1 017 ₽ вместо 1 300
  • Jadran Адиарин Регидрокомплекс, сухая смесь, 60 г, нейтральный, 10 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778186464_3/content/content/gallery":{"title":"Jadran Адиарин Регидрокомплекс, сухая смесь, 60 г, нейтральный, 10 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/5365919/img_id3843100062724138213.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5365919/img_id3843100062724138213.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5365919/img_id3843100062724138213.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5365919/img_id3843100062724138213.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5365919/img_id3843100062724138213.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5365919/img_id3843100062724138213.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/5219318/img_id928400001016884915.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5219318/img_id928400001016884915.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5219318/img_id928400001016884915.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5219318/img_id928400001016884915.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5219318/img_id928400001016884915.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5219318/img_id928400001016884915.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQhqDHvrnizMYUEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIVCODx888GELqnhGwY9uDQByCYj9UH","sign":"mVxdRvzEwI1MdpWj10bEPnL5n+EvHe42e7eXHdNL/+k="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778186464_3/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
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    Jadran Адиарин Регидрокомплекс, сухая смесь, 60 г, нейтральный, 10 шт.

    Цена 417 ₽ вместо 421
  • Янтарная кислота для укрепления иммунитета, нормализации сна, для стрессоустойчивости, для похудения 60 капс
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1891552148_4/content/content/gallery":{"title":"Янтарная кислота для укрепления иммунитета, нормализации сна, для стрессоустойчивости, для похудения 60 капс","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/11395611/2a0000018d8e22cec262ab56e1af97c0ea09/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/11395611/2a0000018d8e22cec262ab56e1af97c0ea09/120x160 120w, https://avatars.mds.yandex.net/get-mpic/11395611/2a0000018d8e22cec262ab56e1af97c0ea09/180x240 180w, https://avatars.mds.yandex.net/get-mpic/11395611/2a0000018d8e22cec262ab56e1af97c0ea09/240x320 240w, https://avatars.mds.yandex.net/get-mpic/11395611/2a0000018d8e22cec262ab56e1af97c0ea09/300x400 300w, https://avatars.mds.yandex.net/get-mpic/11395611/2a0000018d8e22cec262ab56e1af97c0ea09/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/12365257/2a0000018d9c3636d74995b831d903e4103f/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/12365257/2a0000018d9c3636d74995b831d903e4103f/120x160 120w, https://avatars.mds.yandex.net/get-mpic/12365257/2a0000018d9c3636d74995b831d903e4103f/180x240 180w, https://avatars.mds.yandex.net/get-mpic/12365257/2a0000018d9c3636d74995b831d903e4103f/240x320 240w, https://avatars.mds.yandex.net/get-mpic/12365257/2a0000018d9c3636d74995b831d903e4103f/300x400 300w, https://avatars.mds.yandex.net/get-mpic/12365257/2a0000018d9c3636d74995b831d903e4103f/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/12351018/2a0000018d9c363952b0ca2a8627a0266086/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/12351018/2a0000018d9c363952b0ca2a8627a0266086/120x160 120w, https://avatars.mds.yandex.net/get-mpic/12351018/2a0000018d9c363952b0ca2a8627a0266086/180x240 180w, https://avatars.mds.yandex.net/get-mpic/12351018/2a0000018d9c363952b0ca2a8627a0266086/240x320 240w, https://avatars.mds.yandex.net/get-mpic/12351018/2a0000018d9c363952b0ca2a8627a0266086/300x400 300w, https://avatars.mds.yandex.net/get-mpic/12351018/2a0000018d9c363952b0ca2a8627a0266086/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQhqDHvrnizMYUEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCJSX+4UHEL7as6T8Ahia268TIJnDBQ==","sign":"4X2eNUIOyptE2KeCIg5lG59Y3zNo8KyYHu0HLT11UVI="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1891552148_4/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
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    Янтарная кислота для укрепления иммунитета, нормализации сна, для стрессоустойчивости, для похудения 60 капс

    Цена 371 ₽ вместо 721
  • Пластырь бактерицидный 20 штук Fixplast Standart с перфорацией на полимерной основе
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    Пластырь бактерицидный 20 штук Fixplast Standart с перфорацией на полимерной основе

    Цена 128 ₽ вместо 158
  • Марля 3 метра, медицинская Верамед, отбеленная, 3м х 0,9м
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    Марля 3 метра, медицинская Верамед, отбеленная, 3м х 0,9м

    Цена 157 ₽ вместо 249
  • Капсулы PROTEIN.COMPANY Melatonin Мелатонин, 250 мл, 90 шт.
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    Капсулы PROTEIN.COMPANY Melatonin Мелатонин, 250 мл, 90 шт.

    Цена 698 ₽ вместо 950
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    Реклама
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  • Бинт эластичный самофиксирующийся / бандажная лента для животных, для перевязок, для тату, 5 см х 4,5 м, черный, 1 шт
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    Бинт эластичный самофиксирующийся / бандажная лента для животных, для перевязок, для тату, 5 см х 4,5 м, черный, 1 шт

    Цена 127 ₽ вместо 300
  • Марлевый Бинт медицинский стерильный Вариант 5 м х 10 см ГОСТ, 5 шт. в наборе
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    Марлевый Бинт медицинский стерильный Вариант 5 м х 10 см ГОСТ, 5 шт. в наборе

    Цена 190 ₽ вместо 280
  • Бинт медицинский стерильный 5х10 New Life -10 шт
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    Бинт медицинский стерильный 5х10 New Life -10 шт

    Цена 250 ₽ вместо 390
  • Магне B6 таб. п/о, 60 шт.
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    Магне B6 таб. п/о, 60 шт.

    Цена 656 ₽ вместо 762
  • Omega-3 капс., 1000 мг, 100 мл, 30 шт.
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    Omega-3 капс., 1000 мг, 100 мл, 30 шт.

    Цена 526 ₽ вместо 611
  • Жидкий пластырь Fixplast c пантенолом, 60 мл
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    Жидкий пластырь Fixplast c пантенолом, 60 мл

    Цена 318 ₽ вместо 399
  • Газоотводная трубка для новорожденных "Longmed+", синяя
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    Газоотводная трубка для новорожденных "Longmed+", синяя

    Цена 351 ₽ вместо 650
  • Бинт марлевый медицинский стерильный в индивидуальной упаковке Навтекс, 5 м х 10 см, 10 штук
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    Бинт марлевый медицинский стерильный в индивидуальной упаковке Навтекс, 5 м х 10 см, 10 штук

    Цена 265 ₽ вместо 286
  • Эвалар чай Турбослим Очищение ф/п, 2 г, 20 шт.
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    Эвалар чай Турбослим Очищение ф/п, 2 г, 20 шт.

    Цена 358 ₽ вместо 362
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