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Описание

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Итоприд-Вертекс таб. п/о плен., 50 мг, 40 шт.

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5.0
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Количество штук в упаковке, шт.: 40

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Коротко о товаре

Артикул Маркета
4453139453
Тип препарата
Назначение
Действующее вещество
Возраст
от 16 лет
Инструкция
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\u003Cbr/\u003E-функциональная (неязвенная) диспепсия или хронический гастрит."},{"name":"Противопоказания","value":"-повышенная чувствительность к итоприду или любому вспомогательному компоненту препарата; \u003Cbr/\u003E-пациенты с желудочно-кишечным кровотечением, механической обструкцией или перфорацией; \u003Cbr/\u003E-детский возраст до 16 лет (в связи с отсутствием данных по безопасности); \u003Cbr/\u003E-беременность и период грудного вскармливания; \u003Cbr/\u003E-у пациентов с непереносимостью лактозы, дефицитом лактазы и синдромом глюкозо-галактозной мальабсорбции."},{"name":"Состав","value":"Одна таблетка, покрытая пленочной оболочкой, содержит: \u003Cbr/\u003Eдействующее вещество: итоприда гидрохлорид - 50,0 мг; \u003Cbr/\u003Eвспомогательные вещества: лактозы моногидрат, крахмал кукурузный прежелатинизированный, магния стеарат, кроскармеллоза натрия, кремния диоксид коллоидный; \u003Cbr/\u003Eпленочная оболочка: [гипромеллоза, гипролоза (гидроксипропилцеллюлоза), тальк, титана диоксид] или [сухая смесь для пленочного покрытия, содержащая гипромеллозу, гипролозу (гидроксипропилцеллюлозу), тальк, титана диоксид]."},{"name":"Действующее вещество","value":"Итоприд","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["27144131:28708725"]}}},{"name":"Способ применения и дозы","value":"Взрослым назначают внутрь по 1 таблетке препарата (50 мг) 3 раза в сутки до еды. Рекомендуемая суточная доза составляет 150 мг. Указанная доза может быть снижена с учетом возраста и симптомов больного. \u003Cbr/\u003EВ клинических исследованиях продолжительность лечения итопридом составляла до 8 недель."},{"name":"Побочные действия","value":"Следующие побочные эффекты наблюдались у 998 пациентов при применении итоприда в стандартной суточной дозе 150 мг или ниже в ходе 4 плацебо-контролируемых, 4 сравнительных и 13 неконтролируемых интервенционных клинических исследованиях с частотой [часто (≥1/100 и \u003C1/10) и нечасто (≥1/1000 и \u003C1/100)]. В категориях с частотой очень часто (≥1/10), редко (≥1/10000 и \u003C1/1000) или очень редко (\u003C1/10000) нежелательных реакций не наблюдалось. \u003Cbr/\u003EЖелудочно-кишечные нарушения: часто – боль в животе, диарея, нечасто – повышенное слюноотделение;\u003Cbr/\u003EЛабораторные и инструментальные данные: нечасто - Повышение активности аланинаминотрансферазы (АЛТ), снижение количества лейкоцитов; \u003Cbr/\u003EНарушения со стороны нервной системы – нечасто - Головокружение, головная боль; \u003Cbr/\u003EНарушения со стороны кожи и подкожнной клетчатки: нечасто – сыпь. \u003Cbr/\u003EСледующие побочные эффекты были выявлены в ходе пострегистрационного применения итоприда, исходя из имеющихся данных оценить их частоту не представляется возможным. \u003Cbr/\u003EНарушения со стороны крови и лимфатической системы: лейкопения и тромбоцитопения. \u003Cbr/\u003EНарушения со стороны иммунной системы: реакции гиперчувствительности, включая анафилактоидную реакцию. \u003Cbr/\u003EНарушения со стороны эндокринной системы: повышение уровня пролактина в крови. \u003Cbr/\u003EНарушения со стороны нервной системы: головокружение, головная боль, тремор. \u003Cbr/\u003EЖелудочно-кишечные нарушения: диарея, запор, боль в животе, повышенное слюноотделение и тошнота. \u003Cbr/\u003EНарушения со стороны печени и желчевыводящих путей: желтуха. \u003Cbr/\u003EНарушения со стороны кожи и подкожной клетчатки: сыпь, эритема и зуд. \u003Cbr/\u003EНарушения со стороны репродуктивной системы и молочных желез: гинекомастия. \u003Cbr/\u003EЛабораторные и инструментальные данные: повышение активности аспартатаминотрансферазы (ACT), аланинаминотрансферазы (АЛТ), гамма-глтамилтранспептидазы, щелочной фосфатазы и уровня билирубина."},{"name":"Фармакологическое действие","value":"Итоприда гидрохлорид - это гастропрокинетик для приема внутрь. Лекарственная форма и состав таблеток обеспечивают немедленное высвобождение действующего вещества. Итоприд характеризуется двойным механизмом действия: антагонизм к D2-дофаминовым рецепторам и ингибирование ацетилхолинэстеразы. В результате действия итоприда увеличивается концентрация ацетилхолина, что приводит к усилению моторики желудка, повышению тонуса нижнего пищеводного сфинктера (НПС), ускорению процесса опорожнения желудка и улучшению гастродуоденальной координации. \u003Cbr/\u003EИтоприда гидрохлорид также оказывает противорвотный эффект за счет взаимодействия с D2-дофаминовыми рецепторами, расположенными в хеморецепторной триггерной зоне продолговатого мозга. Итоприд вызывает дозозависимое подавление рвоты, вызванной апоморфином. \u003Cbr/\u003EДействие итоприда у пациентов с функциональной диспепсией приводит к снижению выраженности симптомов (общая оценка пациентом, постпрандиальная тяжесть в животе, раннее насыщение). Применение итоприда пациентами с диабетическим гастропарезом способствовало ускорению эвакуации из желудка жидкой и твердой пищи. \u003Cbr/\u003EУ пациентов с гастроэзофагеальной рефлюксной болезнью (ГЭРБ) итоприд уменьшает количество преходящих расслаблений нижнего пищеводного сфинктера и уменьшает продолжительность времени с высокой кислотностью в пищеводе (pH \u003C 4). \u003Cbr/\u003EПри совместном применении итоприда гидрохлорид с альфа-липоевой кислотой наблюдалось ускорение процесса опорожнения желудка и снижение уровня гастрина и мотилина в сравнении с монотерапией итопридом. \u003Cbr/\u003EИтоприда гидрохлорид оказывает высокоспецифичное действие на верхний отдел желудочно-кишечного тракта. Итоприда гидрохлорид ускоряет опорожнение желудка. Итоприда гидрохлорид не влияет на сывороточные уровни гастрина."},{"name":"Фармакологическая группа","value":"моторики ЖКТ стимулятор - ацетилхолина выброса стимулятор"},{"name":"Форма выпуска","value":"таблетки, покрытые пленочной оболочкой"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 16 лет"},{"name":"Условия хранения","value":"Хранить при температуре не выше 25 °С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"При передозировке показаны промывание желудка и симптоматическая терапия."},{"name":"Применение при беременности и кормлении грудью","value":"Беременность\u003Cbr/\u003EНа данный момент имеется ограниченное количество данных (менее 300 исходов беременности) по применению итоприда у беременных женщин. Исследования на животных не выявили признаков прямого или непрямого отрицательного влияния итоприда, указывающих на репродуктивную токсичность. В целях предосторожности следует избегать применения итоприда при беременности. \u003Cbr/\u003EПериод грудного вскармливания\u003Cbr/\u003EИтоприд выделяется с молоком у животных, однако на данный момент отсутствует достаточное количество данных о выделении итоприда с грудным молоком у человека. При кормлении грудью нельзя исключать риск влияния итоприда на ребенка. Решение о прекращении грудного вскармливания или отмене/перерыве в приеме препарата следует принимать, основываясь на оценке пользы грудного вскармливания для ребенка и пользы итоприда для матери."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Исследований относительно влияния итоприда на способность к управлению автомобилем и механизмами не проводилось. Однако в период лечения итопридом следует соблюдать осторожность при выполнении потенциально опасных видов деятельности, требующих повышенной концентрации внимания и быстроты психомоторных реакций (управление транспортными средствами, работа с движущимися механизмами, работа диспетчера и оператора), так как применение итоприда может вызвать головокружение."},{"name":"Особые указания","value":"С осторожностью: \u003Cbr/\u003EИтоприда гидрохлорид усиливает действие ацетилхолина, что может вызывать холинергические побочные реакции. Препарат следует назначать с осторожностью категории пациентов, для которых появление таких реакций может усугубить течение основного заболевания. \u003Cbr/\u003EПациентам пожилого возраста итоприд следует назначать с осторожностью, учитывая более высокую частоту снижения функции печени и почек, наличие сопутствующих заболеваний или другое лечение. \u003Cbr/\u003EИтоприд усиливает действие ацетилхолина и может вызвать холинэргические побочные реакции. Данные о длительном применении итоприда отсутствуют."},{"name":"Взаимодействие","value":"Метаболическое взаимодействие не ожидается, так как итоприд первично метаболизируется под действием флавиновой монооксигеназы, а не с участием системы цитохрома CYP450. \u003Cbr/\u003EПри одновременном применении варфарина, диазепама, диклофенака натрия, тиклопидина гидрохлорида, нифедипина и никардипина гидрохлорида изменений связывания с белками не наблюдалось. \u003Cbr/\u003EИтоприд усиливает моторику желудка, поэтому он может повлиять на всасывание других препаратов, принимаемых внутрь. Особую осторожность следует соблюдать при применении препаратов с низким терапевтическим индексом, а также лекарственных форм с замедленным высвобождением или препаратов с кишечнорастворимой оболочкой. \u003Cbr/\u003EПротивоязвенные препараты, такие как циметидин, ранитидин, тепренон и цетраксат, не влияют на прокинетическое действие итоприда. \u003Cbr/\u003EАнтихолинергические средства могут ослабить эффект итоприда."},{"name":"Регистрационный номер","value":"ЛП-007157"},{"name":"Дата государственной регистрации","value":"05.07.2021"},{"name":"Владелец регистрационного удостоверения","value":"Вертекс","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["34324371:35649313","7893318:8514228"]}}},{"name":"Изготовитель","value":"Вертекс"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Итоприд","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["17796364:35833672"]}}},{"name":"Срок годности","value":"1014 дн."}]}},"fullSpecsGrouped":{"10834871701481141726":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"пищеварительная система"},{"name":"Назначение","value":"вздутие живота, гастрит, диспепсические явления, изжога, рвота, снижение аппетита, тошнота, тяжесть в эпигастральной области"},{"name":"Показания к применению","value":"Применяют для лечения желудочно-кишечных симптомов, связанных с нарушением моторики желудка или его замедленным опорожнением, таких как: \u003Cbr/\u003E-вздутие живота, быстрое насыщение, чувство переполнения в желудке после приема пищи, боль или дискомфорт в эпигастральной области, снижение аппетита, изжога, тошнота и рвота; \u003Cbr/\u003E-функциональная (неязвенная) диспепсия или хронический гастрит."},{"name":"Противопоказания","value":"-повышенная чувствительность к итоприду или любому вспомогательному компоненту препарата; \u003Cbr/\u003E-пациенты с желудочно-кишечным кровотечением, механической обструкцией или перфорацией; \u003Cbr/\u003E-детский возраст до 16 лет (в связи с отсутствием данных по безопасности); \u003Cbr/\u003E-беременность и период грудного вскармливания; \u003Cbr/\u003E-у пациентов с непереносимостью лактозы, дефицитом лактазы и синдромом глюкозо-галактозной мальабсорбции."},{"name":"Состав","value":"Одна таблетка, покрытая пленочной оболочкой, содержит: \u003Cbr/\u003Eдействующее вещество: итоприда гидрохлорид - 50,0 мг; \u003Cbr/\u003Eвспомогательные вещества: лактозы моногидрат, крахмал кукурузный прежелатинизированный, магния стеарат, кроскармеллоза натрия, кремния диоксид коллоидный; \u003Cbr/\u003Eпленочная оболочка: [гипромеллоза, гипролоза (гидроксипропилцеллюлоза), тальк, титана диоксид] или [сухая смесь для пленочного покрытия, содержащая гипромеллозу, гипролозу (гидроксипропилцеллюлозу), тальк, титана диоксид]."},{"name":"Действующее вещество","value":"Итоприд"},{"name":"Способ применения и дозы","value":"Взрослым назначают внутрь по 1 таблетке препарата (50 мг) 3 раза в сутки до еды. Рекомендуемая суточная доза составляет 150 мг. Указанная доза может быть снижена с учетом возраста и симптомов больного. \u003Cbr/\u003EВ клинических исследованиях продолжительность лечения итопридом составляла до 8 недель."},{"name":"Побочные действия","value":"Следующие побочные эффекты наблюдались у 998 пациентов при применении итоприда в стандартной суточной дозе 150 мг или ниже в ходе 4 плацебо-контролируемых, 4 сравнительных и 13 неконтролируемых интервенционных клинических исследованиях с частотой [часто (≥1/100 и \u003C1/10) и нечасто (≥1/1000 и \u003C1/100)]. В категориях с частотой очень часто (≥1/10), редко (≥1/10000 и \u003C1/1000) или очень редко (\u003C1/10000) нежелательных реакций не наблюдалось. \u003Cbr/\u003EЖелудочно-кишечные нарушения: часто – боль в животе, диарея, нечасто – повышенное слюноотделение;\u003Cbr/\u003EЛабораторные и инструментальные данные: нечасто - Повышение активности аланинаминотрансферазы (АЛТ), снижение количества лейкоцитов; \u003Cbr/\u003EНарушения со стороны нервной системы – нечасто - Головокружение, головная боль; \u003Cbr/\u003EНарушения со стороны кожи и подкожнной клетчатки: нечасто – сыпь. \u003Cbr/\u003EСледующие побочные эффекты были выявлены в ходе пострегистрационного применения итоприда, исходя из имеющихся данных оценить их частоту не представляется возможным. \u003Cbr/\u003EНарушения со стороны крови и лимфатической системы: лейкопения и тромбоцитопения. \u003Cbr/\u003EНарушения со стороны иммунной системы: реакции гиперчувствительности, включая анафилактоидную реакцию. \u003Cbr/\u003EНарушения со стороны эндокринной системы: повышение уровня пролактина в крови. \u003Cbr/\u003EНарушения со стороны нервной системы: головокружение, головная боль, тремор. \u003Cbr/\u003EЖелудочно-кишечные нарушения: диарея, запор, боль в животе, повышенное слюноотделение и тошнота. \u003Cbr/\u003EНарушения со стороны печени и желчевыводящих путей: желтуха. \u003Cbr/\u003EНарушения со стороны кожи и подкожной клетчатки: сыпь, эритема и зуд. \u003Cbr/\u003EНарушения со стороны репродуктивной системы и молочных желез: гинекомастия. \u003Cbr/\u003EЛабораторные и инструментальные данные: повышение активности аспартатаминотрансферазы (ACT), аланинаминотрансферазы (АЛТ), гамма-глтамилтранспептидазы, щелочной фосфатазы и уровня билирубина."},{"name":"Фармакологическое действие","value":"Итоприда гидрохлорид - это гастропрокинетик для приема внутрь. Лекарственная форма и состав таблеток обеспечивают немедленное высвобождение действующего вещества. Итоприд характеризуется двойным механизмом действия: антагонизм к D2-дофаминовым рецепторам и ингибирование ацетилхолинэстеразы. В результате действия итоприда увеличивается концентрация ацетилхолина, что приводит к усилению моторики желудка, повышению тонуса нижнего пищеводного сфинктера (НПС), ускорению процесса опорожнения желудка и улучшению гастродуоденальной координации. \u003Cbr/\u003EИтоприда гидрохлорид также оказывает противорвотный эффект за счет взаимодействия с D2-дофаминовыми рецепторами, расположенными в хеморецепторной триггерной зоне продолговатого мозга. Итоприд вызывает дозозависимое подавление рвоты, вызванной апоморфином. \u003Cbr/\u003EДействие итоприда у пациентов с функциональной диспепсией приводит к снижению выраженности симптомов (общая оценка пациентом, постпрандиальная тяжесть в животе, раннее насыщение). Применение итоприда пациентами с диабетическим гастропарезом способствовало ускорению эвакуации из желудка жидкой и твердой пищи. \u003Cbr/\u003EУ пациентов с гастроэзофагеальной рефлюксной болезнью (ГЭРБ) итоприд уменьшает количество преходящих расслаблений нижнего пищеводного сфинктера и уменьшает продолжительность времени с высокой кислотностью в пищеводе (pH \u003C 4). \u003Cbr/\u003EПри совместном применении итоприда гидрохлорид с альфа-липоевой кислотой наблюдалось ускорение процесса опорожнения желудка и снижение уровня гастрина и мотилина в сравнении с монотерапией итопридом. \u003Cbr/\u003EИтоприда гидрохлорид оказывает высокоспецифичное действие на верхний отдел желудочно-кишечного тракта. Итоприда гидрохлорид ускоряет опорожнение желудка. Итоприда гидрохлорид не влияет на сывороточные уровни гастрина."},{"name":"Фармакологическая группа","value":"моторики ЖКТ стимулятор - ацетилхолина выброса стимулятор"},{"name":"Форма выпуска","value":"таблетки, покрытые пленочной оболочкой"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 16 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"Хранить при температуре не выше 25 °С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"При передозировке показаны промывание желудка и симптоматическая терапия."},{"name":"Применение при беременности и кормлении грудью","value":"Беременность\u003Cbr/\u003EНа данный момент имеется ограниченное количество данных (менее 300 исходов беременности) по применению итоприда у беременных женщин. Исследования на животных не выявили признаков прямого или непрямого отрицательного влияния итоприда, указывающих на репродуктивную токсичность. В целях предосторожности следует избегать применения итоприда при беременности. \u003Cbr/\u003EПериод грудного вскармливания\u003Cbr/\u003EИтоприд выделяется с молоком у животных, однако на данный момент отсутствует достаточное количество данных о выделении итоприда с грудным молоком у человека. При кормлении грудью нельзя исключать риск влияния итоприда на ребенка. Решение о прекращении грудного вскармливания или отмене/перерыве в приеме препарата следует принимать, основываясь на оценке пользы грудного вскармливания для ребенка и пользы итоприда для матери."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Исследований относительно влияния итоприда на способность к управлению автомобилем и механизмами не проводилось. Однако в период лечения итопридом следует соблюдать осторожность при выполнении потенциально опасных видов деятельности, требующих повышенной концентрации внимания и быстроты психомоторных реакций (управление транспортными средствами, работа с движущимися механизмами, работа диспетчера и оператора), так как применение итоприда может вызвать головокружение."},{"name":"Особые указания","value":"С осторожностью: \u003Cbr/\u003EИтоприда гидрохлорид усиливает действие ацетилхолина, что может вызывать холинергические побочные реакции. Препарат следует назначать с осторожностью категории пациентов, для которых появление таких реакций может усугубить течение основного заболевания. \u003Cbr/\u003EПациентам пожилого возраста итоприд следует назначать с осторожностью, учитывая более высокую частоту снижения функции печени и почек, наличие сопутствующих заболеваний или другое лечение. \u003Cbr/\u003EИтоприд усиливает действие ацетилхолина и может вызвать холинэргические побочные реакции. Данные о длительном применении итоприда отсутствуют."},{"name":"Взаимодействие","value":"Метаболическое взаимодействие не ожидается, так как итоприд первично метаболизируется под действием флавиновой монооксигеназы, а не с участием системы цитохрома CYP450. \u003Cbr/\u003EПри одновременном применении варфарина, диазепама, диклофенака натрия, тиклопидина гидрохлорида, нифедипина и никардипина гидрохлорида изменений связывания с белками не наблюдалось. \u003Cbr/\u003EИтоприд усиливает моторику желудка, поэтому он может повлиять на всасывание других препаратов, принимаемых внутрь. Особую осторожность следует соблюдать при применении препаратов с низким терапевтическим индексом, а также лекарственных форм с замедленным высвобождением или препаратов с кишечнорастворимой оболочкой. \u003Cbr/\u003EПротивоязвенные препараты, такие как циметидин, ранитидин, тепренон и цетраксат, не влияют на прокинетическое действие итоприда. \u003Cbr/\u003EАнтихолинергические средства могут ослабить эффект итоприда."},{"name":"Регистрационный номер","value":"ЛП-007157"},{"name":"Дата государственной регистрации","value":"05.07.2021"},{"name":"Владелец регистрационного удостоверения","value":"Вертекс"},{"name":"Изготовитель","value":"Вертекс"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Итоприд"},{"name":"Срок годности","value":"1014 дн."}]}],"transitionId":"tr_5"}}}}
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Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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Рекомендуемая суточная доза составляет 150 мг. Указанная доза может быть снижена с учетом возраста и симптомов больного. \u003Cbr/\u003EВ клинических исследованиях продолжительность лечения итопридом составляла до 8 недель."},{"description":"","filters":[{"id":15767998,"name":"Побочные действия"}],"isMainProperty":false,"name":"Побочные действия","value":"Следующие побочные эффекты наблюдались у 998 пациентов при применении итоприда в стандартной суточной дозе 150 мг или ниже в ходе 4 плацебо-контролируемых, 4 сравнительных и 13 неконтролируемых интервенционных клинических исследованиях с частотой [часто (≥1/100 и \u003C1/10) и нечасто (≥1/1000 и \u003C1/100)]. В категориях с частотой очень часто (≥1/10), редко (≥1/10000 и \u003C1/1000) или очень редко (\u003C1/10000) нежелательных реакций не наблюдалось. \u003Cbr/\u003EЖелудочно-кишечные нарушения: часто – боль в животе, диарея, нечасто – повышенное слюноотделение;\u003Cbr/\u003EЛабораторные и инструментальные данные: нечасто - Повышение активности аланинаминотрансферазы (АЛТ), снижение количества лейкоцитов; \u003Cbr/\u003EНарушения со стороны нервной системы – нечасто - Головокружение, головная боль; \u003Cbr/\u003EНарушения со стороны кожи и подкожнной клетчатки: нечасто – сыпь. \u003Cbr/\u003EСледующие побочные эффекты были выявлены в ходе пострегистрационного применения итоприда, исходя из имеющихся данных оценить их частоту не представляется возможным. \u003Cbr/\u003EНарушения со стороны крови и лимфатической системы: лейкопения и тромбоцитопения. \u003Cbr/\u003EНарушения со стороны иммунной системы: реакции гиперчувствительности, включая анафилактоидную реакцию. \u003Cbr/\u003EНарушения со стороны эндокринной системы: повышение уровня пролактина в крови. \u003Cbr/\u003EНарушения со стороны нервной системы: головокружение, головная боль, тремор. \u003Cbr/\u003EЖелудочно-кишечные нарушения: диарея, запор, боль в животе, повышенное слюноотделение и тошнота. \u003Cbr/\u003EНарушения со стороны печени и желчевыводящих путей: желтуха. \u003Cbr/\u003EНарушения со стороны кожи и подкожной клетчатки: сыпь, эритема и зуд. \u003Cbr/\u003EНарушения со стороны репродуктивной системы и молочных желез: гинекомастия. \u003Cbr/\u003EЛабораторные и инструментальные данные: повышение активности аспартатаминотрансферазы (ACT), аланинаминотрансферазы (АЛТ), гамма-глтамилтранспептидазы, щелочной фосфатазы и уровня билирубина."},{"description":"","filters":[{"id":15768001,"name":"Фармакологическое действие"}],"isMainProperty":false,"name":"Фармакологическое действие","value":"Итоприда гидрохлорид - это гастропрокинетик для приема внутрь. Лекарственная форма и состав таблеток обеспечивают немедленное высвобождение действующего вещества. Итоприд характеризуется двойным механизмом действия: антагонизм к D2-дофаминовым рецепторам и ингибирование ацетилхолинэстеразы. В результате действия итоприда увеличивается концентрация ацетилхолина, что приводит к усилению моторики желудка, повышению тонуса нижнего пищеводного сфинктера (НПС), ускорению процесса опорожнения желудка и улучшению гастродуоденальной координации. \u003Cbr/\u003EИтоприда гидрохлорид также оказывает противорвотный эффект за счет взаимодействия с D2-дофаминовыми рецепторами, расположенными в хеморецепторной триггерной зоне продолговатого мозга. Итоприд вызывает дозозависимое подавление рвоты, вызванной апоморфином. \u003Cbr/\u003EДействие итоприда у пациентов с функциональной диспепсией приводит к снижению выраженности симптомов (общая оценка пациентом, постпрандиальная тяжесть в животе, раннее насыщение). Применение итоприда пациентами с диабетическим гастропарезом способствовало ускорению эвакуации из желудка жидкой и твердой пищи. \u003Cbr/\u003EУ пациентов с гастроэзофагеальной рефлюксной болезнью (ГЭРБ) итоприд уменьшает количество преходящих расслаблений нижнего пищеводного сфинктера и уменьшает продолжительность времени с высокой кислотностью в пищеводе (pH \u003C 4). \u003Cbr/\u003EПри совместном применении итоприда гидрохлорид с альфа-липоевой кислотой наблюдалось ускорение процесса опорожнения желудка и снижение уровня гастрина и мотилина в сравнении с монотерапией итопридом. \u003Cbr/\u003EИтоприда гидрохлорид оказывает высокоспецифичное действие на верхний отдел желудочно-кишечного тракта. Итоприда гидрохлорид ускоряет опорожнение желудка. Итоприда гидрохлорид не влияет на сывороточные уровни гастрина."},{"description":"","filters":[{"id":34045110,"name":"Фармакологическая группа"}],"isMainProperty":false,"name":"Фармакологическая группа","value":"моторики ЖКТ стимулятор - ацетилхолина выброса стимулятор"},{"description":"","filters":[{"id":27141511,"name":"Форма выпуска для карточки"}],"isMainProperty":false,"name":"Форма выпуска","value":"таблетки, покрытые пленочной оболочкой"},{"description":"","filters":[{"id":35947170,"name":"Способ применения/введения"}],"isMainProperty":false,"name":"Способ применения/введения","value":"пероральный"},{"description":"","filters":[{"id":23679511,"name":"Минимальный возраст применения"},{"id":16082123,"name":"С рождения"}],"isMainProperty":false,"name":"Минимальный возраст применения","value":"от 16 лет"}]},{"name":"Дополнительно","specs":[{"description":"","filters":[{"id":15767999,"name":"Условия хранения"}],"isMainProperty":false,"name":"Условия хранения","value":"Хранить при температуре не выше 25 °С. Хранить в недоступном для детей месте."},{"description":"","filters":[{"id":15768014,"name":"Передозировка"}],"isMainProperty":false,"name":"Передозировка","value":"При передозировке показаны промывание желудка и симптоматическая терапия."},{"description":"","filters":[{"id":15768015,"name":"Применение при беременности и кормлении грудью"}],"isMainProperty":false,"name":"Применение при беременности и кормлении грудью","value":"Беременность\u003Cbr/\u003EНа данный момент имеется ограниченное количество данных (менее 300 исходов беременности) по применению итоприда у беременных женщин. Исследования на животных не выявили признаков прямого или непрямого отрицательного влияния итоприда, указывающих на репродуктивную токсичность. В целях предосторожности следует избегать применения итоприда при беременности. \u003Cbr/\u003EПериод грудного вскармливания\u003Cbr/\u003EИтоприд выделяется с молоком у животных, однако на данный момент отсутствует достаточное количество данных о выделении итоприда с грудным молоком у человека. При кормлении грудью нельзя исключать риск влияния итоприда на ребенка. Решение о прекращении грудного вскармливания или отмене/перерыве в приеме препарата следует принимать, основываясь на оценке пользы грудного вскармливания для ребенка и пользы итоприда для матери."},{"description":"","filters":[{"id":17360993,"name":"Влияние на способность управлять транспортом и механизмами"}],"isMainProperty":false,"name":"Влияние на способность управлять транспортом и механизмами","value":"Исследований относительно влияния итоприда на способность к управлению автомобилем и механизмами не проводилось. Однако в период лечения итопридом следует соблюдать осторожность при выполнении потенциально опасных видов деятельности, требующих повышенной концентрации внимания и быстроты психомоторных реакций (управление транспортными средствами, работа с движущимися механизмами, работа диспетчера и оператора), так как применение итоприда может вызвать головокружение."},{"description":"","filters":[{"id":15771167,"name":"Особые указания"}],"isMainProperty":false,"name":"Особые указания","value":"С осторожностью: \u003Cbr/\u003EИтоприда гидрохлорид усиливает действие ацетилхолина, что может вызывать холинергические побочные реакции. 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Еще может подойти

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Инструкция

Показания к применению

Применяют для лечения желудочно-кишечных симптомов, связанных с нарушением моторики желудка или его замедленным опорожнением, таких как:
-вздутие живота, быстрое насыщение, чувство переполнения в желудке после приема пищи, боль или дискомфорт в эпигастральной области, снижение аппетита, изжога, тошнота и рвота;
-функциональная (неязвенная) диспепсия или хронический гастрит.

Противопоказания

-повышенная чувствительность к итоприду или любому вспомогательному компоненту препарата;
-пациенты с желудочно-кишечным кровотечением, механической обструкцией или перфорацией;
-детский возраст до 16 лет (в связи с отсутствием данных по безопасности);
-беременность и период грудного вскармливания;
-у пациентов с непереносимостью лактозы, дефицитом лактазы и синдромом глюкозо-галактозной мальабсорбции.

Способ применения и дозы

Взрослым назначают внутрь по 1 таблетке препарата (50 мг) 3 раза в сутки до еды. Рекомендуемая суточная доза составляет 150 мг. Указанная доза может быть снижена с учетом возраста и симптомов больного.
В клинических исследованиях продолжительность лечения итопридом составляла до 8 недель.
Полная инструкция
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Итоприд-Вертекс таб. п/о плен.
Итоприд-Вертекс таб. п/о плен., 50 мг, 40 шт.
5.0
(2)
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Инструкция

304 ₽

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5.0
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    Цена 251 ₽
  • Мирамистин р-р д/мест. прим. фл. с распыл., 0.01%, 50 мл
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    Мирамистин р-р д/мест. прим. фл. с распыл., 0.01%, 50 мл

    Цена 422 ₽ вместо 430
  • Отофаг гель с бактериофагами фл., 50 мл
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    Отофаг гель с бактериофагами фл., 50 мл

    Цена 1 059 ₽
  • Эвалар Чай Эвалар БИО при повышенном содержании мочевой кислоты, 20 фильтр-пакетов
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    Эвалар Чай Эвалар БИО при повышенном содержании мочевой кислоты, 20 фильтр-пакетов

    Цена 236 ₽ вместо 238
  • Реклама
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  • Гилан Комфорт увлажн. гл. р-р, 0.18%, 0.4 мл, 30 шт.
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    Гилан Комфорт увлажн. гл. р-р, 0.18%, 0.4 мл, 30 шт.

    Цена 449 ₽
  • Олиджим таб., 30 г, 100 шт.
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    Олиджим таб., 30 г, 100 шт.

    Цена 560 ₽ вместо 622
  • Тиоктовая кислота-ВЕРТЕКС таб. п/о плен., 600 мг, 28 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1662244227_11/content/content/gallery":{"title":"Тиоктовая кислота-ВЕРТЕКС таб. п/о плен., 600 мг, 28 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/5262552/img_id2254990001304074393.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5262552/img_id2254990001304074393.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5262552/img_id2254990001304074393.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5262552/img_id2254990001304074393.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5262552/img_id2254990001304074393.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5262552/img_id2254990001304074393.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/5207288/img_id1688605523510026303.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5207288/img_id1688605523510026303.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5207288/img_id1688605523510026303.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5207288/img_id1688605523510026303.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5207288/img_id1688605523510026303.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5207288/img_id1688605523510026303.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQl7b9jO6d0Ks1EhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIXCIOrz5gGEOXcnrz6Ahi01YcEINrZwQc=","sign":"5AeeUtZTcbT6aerxl7Lt73j4B68pHEaCEhDPv+j+hrQ="},"target":"model_card"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1662244227_11/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
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    Тиоктовая кислота-ВЕРТЕКС таб. п/о плен., 600 мг, 28 шт.

    Цена 663 ₽
  • Детралекс таб. п/о плен., 500 мг, 30 шт.
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    Детралекс таб. п/о плен., 500 мг, 30 шт.

    Цена 999 ₽ вместо 1 009
  • Ревмафлекс капс., 60 шт.
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    Ревмафлекс капс., 60 шт.

    Цена 888 ₽ вместо 987
  • Тербинафин крем, 1%, 15 г, 1 шт.
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    Тербинафин крем, 1%, 15 г, 1 шт.

    Цена 215 ₽ вместо 219
  • Нафтизин капли наз. фл.-кап., 0.1%, 15 мл
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    Нафтизин капли наз. фл.-кап., 0.1%, 15 мл

    Цена 175 ₽ вместо 179
  • ЛимфоТранзит концентрат напитка фл., 100 мл
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    ЛимфоТранзит концентрат напитка фл., 100 мл

    Цена 332 ₽ вместо 390
  • Вобэнзим таб. п/о кш/раств., 40 шт.
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    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:228042487_17/content/content/toggleWishlist":{"skuId":"101295552744","productId":228042487,"offerId":"xYLClT0wlnk5HVUlpCbJ0A","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQl7b9jO6d0Ks1EhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCPfN3mwQ6PG9rfkCGJTh0Acg8tzBBw==","sign":"Oqcx9Jbg364qb55VU2iC9AnT04bFp9Cr1xHhELgj/S0="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:228042487_17/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Вобэнзим таб. п/о кш/раств., 40 шт.

    Цена 712 ₽ вместо 719
  • Урсодезоксихолевая кислота-Вертекс капс., 250 мг, 50 шт.
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    Урсодезоксихолевая кислота-Вертекс капс., 250 мг, 50 шт.

    Цена 774 ₽
  • Низорал шампунь, 2%, 120 мл, 1 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:995921009_19/content/content/gallery":{"title":"Низорал шампунь, 2%, 120 мл, 1 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/4501142/img_id1727230457728177366.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4501142/img_id1727230457728177366.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4501142/img_id1727230457728177366.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4501142/img_id1727230457728177366.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4501142/img_id1727230457728177366.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4501142/img_id1727230457728177366.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/5255532/img_id6672654662681195026.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5255532/img_id6672654662681195026.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5255532/img_id6672654662681195026.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5255532/img_id6672654662681195026.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5255532/img_id6672654662681195026.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5255532/img_id6672654662681195026.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4968510/img_id5776048681346308822.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4968510/img_id5776048681346308822.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4968510/img_id5776048681346308822.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4968510/img_id5776048681346308822.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4968510/img_id5776048681346308822.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4968510/img_id5776048681346308822.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4709279/img_id6135241791884028461.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4709279/img_id6135241791884028461.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4709279/img_id6135241791884028461.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4709279/img_id6135241791884028461.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4709279/img_id6135241791884028461.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4709279/img_id6135241791884028461.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQl7b9jO6d0Ks1EhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIVCPGY8toDENr4lFkY1MSSBSDh2cEH","sign":"fWqXzx9rkK6/CdWc1+r7s28dftVqjMc2xOBdWSmTPwU="},"target":"model_card"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:995921009_19/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:995921009_19/content/content/toggleWishlist":{"skuId":"186989658","productId":995921009,"offerId":"cWwdIboWkStArfKUknMkVQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQl7b9jO6d0Ks1EhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIVCPGY8toDENr4lFkY1MSSBSDh2cEH","sign":"fWqXzx9rkK6/CdWc1+r7s28dftVqjMc2xOBdWSmTPwU="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:995921009_19/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Низорал шампунь, 2%, 120 мл, 1 шт.

    Цена 1 064 ₽ вместо 1 075
  • Нифуроксазид-ВЕРТЕКС капс., 200 мг, 14 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1827561606_20/content/content/toggleWishlist":{"skuId":"661508063","productId":1827561606,"offerId":"ChRW6uSwadeu3FStNbK8pg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQl7b9jO6d0Ks1EhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCIbBuecGEN+ft7sCGLTVhwQg2tnBBw==","sign":"Vf5GFWs1pSkB9CIAuKWd4+fbdHuikt1bWcuT4Hcql/c="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1827561606_20/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Нифуроксазид-ВЕРТЕКС капс., 200 мг, 14 шт.

    Цена 301 ₽ вместо 304
  • Реклама
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  • Метрогил Дента стомат. гель туба, 20 г
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    Метрогил Дента стомат. гель туба, 20 г

    Цена 624 ₽ вместо 636
  • Мебеверин-Вертекс капс. пролонг. высвоб. действ. действ., 200 мг, 30 шт.
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    Мебеверин-Вертекс капс. пролонг. высвоб. действ. действ., 200 мг, 30 шт.

    Цена 431 ₽
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