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Калия хлорид конц. д/приг. р-ра д/инф., 40 мг/мл, 10 мл, 10 шт.

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Коротко о товаре

Артикул Маркета
4319894583
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
{"widgets":{"@card/SpecsList":{"/content/page/fancyPage/productSpecsList":{"wrapperProps":{"margins":{"top":4,"bottom":4}},"specsLimit":5,"title":"Коротко о товаре","titleSize":"14","type":"minimal","offset":"s","isHealthCategory":true,"forceShowWidget":true,"withFridge":true}}},"meta":{"/content/page/fancyPage/productSpecsList":{"name":"@card/SpecsList"}},"collections":{"minimalSpecs":{"13814649920191844172":{"specItems":[{"name":"Артикул Маркета","value":"4319894583","withCopyValueButton":true},{"name":"тип препарата","value":"рецептурный лекарственный препарат","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["27272850:1,0","34324371:35649313"]}}},{"name":"назначение","value":"аритмия, гипокалиемия","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["36476390:36618440,36617877"]}}},{"name":"действующее вещество","value":"Калия хлорид","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["27144131:28709861"]}}},{"name":"возраст","value":"от 18 лет"},{"name":"форма выпуска","value":"концентрат для приготовления раствора для инфузий"},{"name":"страна-производитель","value":"Россия"}]}},"compactSpecs":{"13814649920191844172":{"specItems":[{"name":"Артикул Маркета","value":"4319894583","withCopyValueButton":true},{"name":"Тип препарата","value":"Рецептурный лекарственный препарат","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["27272850:1,0","34324371:35649313"]}}},{"name":"Назначение","value":"Аритмия, гипокалиемия","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["36476390:36618440,36617877"]}}},{"name":"Действующее вещество","value":"Калия хлорид","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["27144131:28709861"]}}},{"name":"Возраст","value":"От 18 лет"}]}},"fullSpecs":{"13814649920191844172":{"specItems":[{"name":"Тип препарата","value":"лекарственный препарат","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["34324371:35649313"]}}},{"name":"Рецептурный препарат","value":"да","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["27272850:1,0"]}}},{"name":"Органы и системы","value":"кровеносная система"},{"name":"Назначение","value":"аритмия, гипокалиемия","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["36476390:36618440,36617877"]}}},{"name":"Показания к применению","value":"Гипокалиемия различного генеза, в том числе аритмии, обусловленные гипокалиемией."},{"name":"Противопоказания","value":"- Повышенная чувствительность к компонентам препарата;\u003Cbr /\u003E- гиперкалиемия или гиперхлоремия любой этиологии, полная атриовентрикулярная или внутрижелудочковая блокада;\u003Cbr /\u003E- почечная недостаточность с олигурией или азотемией;\u003Cbr /\u003E- фибрилляция желудочков;\u003Cbr /\u003E- Болезнь Аддисона;\u003Cbr /\u003E- гиперадренализм, ассоциированный с адреногенитальным синдромом;\u003Cbr /\u003E- экстенсивный распад тканей (в т.ч. при тяжелых ожогах);\u003Cbr /\u003E- острая дегидратация;\u003Cbr /\u003E- тепловые судороги;\u003Cbr /\u003E- состояния с повышенной чувствительностью к введению калия (в т.ч. наследственная эпизодическая адинамия или врожденная парамиотония);\u003Cbr /\u003E- сопутствующая терапия солями калия и калийсберегающими диуретиками;\u003Cbr /\u003E- возраст до 18 лет."},{"name":"Состав","value":"Действующее вещество: калия хлорид - 30, 40, 75 или 150 мг\u003Cbr /\u003EВспомогательные вещества: - хлористоводородной кислоты раствор 1М - до pH 3,0-4,0, вода для инъекций - до 1 мл\u003Cbr /\u003EТеоретическая осмолярность:\u003Cbr /\u003E\t\u003Cbr /\u003E805 мОсм/л (30 мг/мл концентрат)\u003Cbr /\u003E\t\u003Cbr /\u003E1074 мОсм/л (40 мг/мл концентрат)\u003Cbr /\u003E\t\u003Cbr /\u003E2013 мОсм/л (75 мг/мл концентрат)\u003Cbr /\u003E\t\u003Cbr /\u003E4026 мОсм/л (150 мг/мл концентрат)."},{"name":"Действующее вещество","value":"Калия хлорид","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["27144131:28709861"]}}},{"name":"Способ применения и дозы","value":"Препарат вводят внутривенно капельно только после разведения концентрата в 10 раз.\u003Cbr /\u003E10 мл концентрата калия хлорида 40 мг/мл разводят водой для инъекций в 10 раз (до 100 мл) для получения изотонического раствора (концентрация калия хлорида составит 4 мг/мл или 0,4%) и вводят внутривенно капельно (со скоростью 20-30 капель в минуту).\u003Cbr /\u003EОдновременно за одну инфузию вводят не более 100 мл приготовленного раствора. При необходимости вливание можно повторить, но общая суточная доза не должна превышать 300-500 мл приготовленного раствора с концентрацией калия хлорида 4 мг/мл (0,4%).\u003Cbr /\u003EДля внутривенного капельного введения можно готовить раствор из расчета до 2,5 г калия хлорида в 500 мл изотонического 0,9% раствора натрия хлорида или 5% раствора декстрозы (глюкозы).\u003Cbr /\u003EДля профилактики и лечения эктопических аритмий при инфаркте миокарда - применяется поляризующая смесь: раствор калия хлорида 2-2,5 г в 500 мл 5-10% декстрозы (глюкозы), к которому добавляют инсулин короткого действия из расчета 1 ЕД на 3-4 г сухой декстрозы (глюкозы).\u003Cbr /\u003EДозы\u003Cbr /\u003EДоза для лечения дефицита калия должна быть подобрана в соответствии с фактической концентрацией электролитов в плазме крови и показателей кислотно-основного состояния.\u003Cbr /\u003E1 ммоль калия (К+) соответствует 75 мг калия хлорида (КС1).\u003Cbr /\u003EВзрослые и пожилые пациенты:\u003Cbr /\u003EДоза для лечения умеренного, бессимптомного дефицита калия и при поддерживающей терапии:\u003Cbr /\u003EКоличество калия, необходимое для коррекции умеренного дефицита калия и при поддерживающей терапии может быть рассчитано по следующей формуле:\u003Cbr /\u003Eтребуемое количество ммоль К+=(МТ* [кг] х 0,2)** х 2 х (целевая концентрация К+ в плазме крови***- фактическая концентрация К+ в плазме крови [ммоль/л])\u003Cbr /\u003Eгде:\u003Cbr /\u003E*МТ= масса тела;\u003Cbr /\u003E** значение представляет собой внеклеточный объем жидкости;\u003Cbr /\u003E*** целевая концентрация К+ в плазме крови должна быть равна 4,5 ммоль калия/л.\u003Cbr /\u003EМаксимальная суточная доза (например, в случае тяжелой симптоматической гипокалиемии или значительных потерь):\u003Cbr /\u003EДо 2-3 ммоль калия/кг массы тела.\u003Cbr /\u003EМаксимальная скорость введения:\u003Cbr /\u003EДо 20 ммоль калия/час у взрослых (соответствует 0,3 ммоль калия/кг массы тела /час). Если концентрация калия в плазме крови составляет менее 2 ммоль калия/л, скорость инфузии может достигать 40 ммоль калия/час.\u003Cbr /\u003EПациенты с сахарным диабетом:\u003Cbr /\u003EИзменение кислотно-основного состояния оказывает влияние на концентрацию калия в плазме крови. Потребность в калии увеличивается при компенсации кетоацидоза у пациентов с сахарным диабетом, а также при введении декстрозы/инсулина короткого действия."},{"name":"Побочные действия","value":"Неблагоприятные побочные реакции могут развиться в виде симптомов гиперкалиемии только в случае абсолютной или относительной передозировки и/или слишком высокой скорости инфузии.\u003Cbr /\u003EЧастота развития неблагоприятных побочных реакций зависит от дозы.\u003Cbr /\u003EНарушения со стороны иммунной системы: аллергические реакции.\u003Cbr /\u003EНарушения со стороны обмена веществ и питания: ацидоз, гиперхлоремия, гиперкалиемия.\u003Cbr /\u003EНарушения со стороны нервной системы: утомляемость, мышечная слабость, спутанность сознания, тяжесть в конечностях, мышечные судороги, парестезии, восходящий паралич.\u003Cbr /\u003EНарушения со стороны сердца: брадикардия, AV блокада, фибрилляция желудочков, остановка сердца.\u003Cbr /\u003EСлишком высокая скорость инфузии может вызвать сердечную аритмию.\u003Cbr /\u003EНарушения со стороны сосудов: снижение артериального давления, централизация кровообращения.\u003Cbr /\u003EНарушения со стороны желудочно-кишечного тракта: тошнота."},{"name":"Фармакологическое действие","value":"Механизм действия\u003Cbr /\u003EКалий является важнейшим катионом внутриклеточного пространства, около 98% общего содержания калия в организме находится во внутриклеточной жидкости.\u003Cbr /\u003EКалий участвует в электрохимических процессах клетки, а также в углеводном и белковом обменах. Во время синтеза гликогена и белков калий потребляется клетками, а в процессе расщепления этих субстратов калий высвобождается (около 0,4-1 ммоль калия/г гликогена и около 2-3 ммоль калия/г выводимого азота).\u003Cbr /\u003EТерапевтический эффект\u003Cbr /\u003EТерапевтическим эффектом растворов калия хлорида для внутривенного введения является предотвращение или лечение дефицита калия, когда пероральный прием (или энтеральное введение) невозможен или недостаточен.\u003Cbr /\u003EСуточная потребность в калии составляет около 1-1,5 ммоль/кг массы тела.\u003Cbr /\u003EДефицит калия может быть вызван повышением почечной экскреции, увеличением потерь через желудочно-кишечный тракт, например, при рвоте, диарее или через свищи, повышением внутриклеточного потребления, например, при лечении ацидоза или введении декстрозы и инсулина, а также при недостаточном потреблении калия.\u003Cbr /\u003EГипокалиемия сопровождается мышечной слабостью, атонией гладких мышц желудочно-кишечного тракта (от запора до кишечной непроходимости), потерей способности почек концентрировать мочу, изменениями ЭКГ и сердечной аритмией."},{"name":"Фармакологическая группа","value":"калия препарат"},{"name":"Форма выпуска","value":"концентрат для приготовления раствора для инфузий"},{"name":"Способ применения/введения","value":"парентеральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["35947170:36763748"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"При температуре не выше 30 °С. Хранить в недоступном для детей месте."},{"name":"Условия отпуска из аптеки","value":"По накладным для ЛПУ."},{"name":"Передозировка","value":"Симптомы: нарушение экскреторного механизма или слишком быстрое внутривенное введение калия может привести к фатальной гиперкалиемии (повышение содержания ионов калия в сыворотке крови выше 5,5 мэкв/л), проявлениями которой являются: мышечный гипотонус, парестезии конечностей, замедление атриовентрикулярной проводимости, аритмии, остановка сердца.\u003Cbr /\u003EРанние изменения электрокардиограммы - высокий зубец Т с заостренной вершиной и узким основанием, наиболее выраженный в грудных отведениях V2-V4 проявляются при повышении концентрации ионов калия в сыворотке крови до 5,5-6,5 мэкв/л. При умеренной гиперкалиемии (содержание ионов калия в сыворотке крови 6,5-8,0 мэкв/л) электрокардиографическими признаками являются: уменьшение амплитуды зубца Р, удлинение интервала QT, расширение комплекса QRS, снижение амплитуды зубца R, желудочковая экстрасистолия.\u003Cbr /\u003EБолее тяжелые симптомы гиперкалиемии - паралич мускулатуры и остановка сердца (изменение на электрокардиограмме - медленный или ускоренный идиовентрикулярный ритм, фибрилляция желудочков, асистолия) развиваются при содержании ионов калия в сыворотке крови 9-14 мэкв/л.\u003Cbr /\u003EЛечение: прекращение инфузии Калия хлорида. Внутрь или внутривенно - раствор натрия хлорида; внутривенно 300-500 мл 5% раствора декстрозы (с 10-20 ЕД инсулина короткого действия на 1 л); коррекция ацидоза (при наличии) с помощью внутривенного введения натрия гидрокарбоната при необходимости - гемодиализ и перитонеальный диализ.\u003Cbr /\u003EАритмия или сывороточная концентрация калия свыше 6,5 ммоль/л требует немедленного лечения с помощью внутривенного введения 10-20 мл 10% раствора кальция глюконата в течение 1-5 минут. При лечении гиперкалиемии у пациентов, находящихся на лечении сердечными гликозидами, быстрое снижение концентрации калия в сыворотке крови может приводить к дигиталисной интоксикации. При лечении передозировки необходимо проводить непрерывный ЭКГ-мониторинг, периодически определять мочевину, электролиты и креатинин в плазме крови, контроль концентрации калия (при необходимости, каждые 2-3 ч), бессимптомных пациентов необходимо наблюдать в течение 6 ч."},{"name":"Применение при беременности и кормлении грудью","value":"При назначении препарата беременным женщинам следует соблюдать осторожность. Препарат должен применяться только при явных показаниях к его применению, если ожидаемая польза для матери превышает потенциальный риск для плода (по возможности назначают препараты калия для приема внутрь).\u003Cbr /\u003EКалий выводится с грудным молоком. При назначении препарата кормящим женщинам следует соблюдать осторожность (по возможности назначают препараты калия для приема внутрь)."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В период лечения препаратом следует соблюдать осторожность при выполнении потенциально опасных видов деятельности, требующих повышенной концентрации внимания и быстроты психомоторных реакций (управление транспортными средствами, работа с движущимися механизмами, работа диспетчера и оператора)."},{"name":"Особые указания","value":"С осторожностью:\u003Cbr /\u003E- Атриовентрикулярная блокада I-II степени, сердечная недостаточность;\u003Cbr /\u003E- серповидноклеточная анемия;\u003Cbr /\u003E- заболевания и состояния, сопровождающиеся нарушением экскреции калия, в т.ч. хроническая почечная недостаточность;\u003Cbr /\u003E- надпочечниковая недостаточность;\u003Cbr /\u003E- У пациентов, принимающих сердечные гликозиды, антагонисты альдостерона, ингибиторы АПФ, такролимус, циклоспорин, гепарин длительного действия, суксаметоний или потенциально нефротоксичные лекарственные препараты (нестероидные противовоспалительные препараты, анальгетики периферического действия).\u003Cbr /\u003EВ период лечения необходимо проводить мониторинг концентрации калия в сыворотке крови во время введения и своевременно корректировать дозу. Кроме того (особенно при заболевании сердца, почек или наличии ацидоза), рекомендуется контроль кислотно-щелочного баланса, электролитов сыворотки, ЭКГ и клинического состояния пациента.\u003Cbr /\u003EГиперкалиемия развивается быстро и протекает бессимптомно и потенциально может привести к блокаде внутрисердечного проведения и летальному исходу. Ранние признаки гиперкалиемии - гипотонус и парестезии конечностей.\u003Cbr /\u003EЛечение гипокалиемии не должно проводится одновременным введением солей калия и калийсберегающих диуретиков во избежание тяжелой гиперкалиемии.\u003Cbr /\u003EЛечение препаратами калия не должно проводится при заболеваниях, сопровождающихся блокадами сердца, поскольку это может повышать степень блокады.\u003Cbr /\u003EНа начальном этапе лечения следует избегать введения одновременно с глюкозой, поскольку это может способствовать дальнейшему снижению концентрации калия.\u003Cbr /\u003EНеобходимо обеспечить исключительно внутривенное введение препарата, поскольку околовенозное введение может вызвать некроз тканей.\u003Cbr /\u003EВведение калия хлорида в вены небольшого диаметра может сопровождаться болезненностью в месте введения.\u003Cbr /\u003EРаствор следует использовать только если он прозрачен и флакон не поврежден.\u003Cbr /\u003EПрепарат применять только разведенным в совместимом растворе для инфузий. Препарат разводить непосредственно после вскрытия флакона. При разведении препарата требуется строгое соблюдение правил асептики.\u003Cbr /\u003EРаствор использовать только если он прозрачен и ампула не повреждена.\u003Cbr /\u003EПрепарат разводить непосредственно после вскрытия ампулы. При разведении препарата требуется строгое соблюдение правил асептики.\u003Cbr /\u003EАмпула только для одноразового использования. Исключение составляют разведения, приготовленные в контролируемых и асептических условиях.\u003Cbr /\u003EС точки зрения микробиологической безопасности разведенный препарат должен быть использован немедленно."},{"name":"Взаимодействие","value":"Одновременное введение с калийсберегающими диуретиками (в т.ч. триамтерен, спиронолактон, амилорид) может привести к тяжелой гиперкалиемии за счет снижения почечной экскреции ионов калия.\u003Cbr /\u003EИнгибиторы АПФ - риск развития гиперкалиемии, поскольку ингибиторы АПФ снижают секрецию альдостерона, что приводит к задержке калия в организме.\u003Cbr /\u003EБета-адреноблокаторы повышали как максимальную концентрацию калия в сыворотке крови, так и время, необходимое для ее возвращения к исходному уровню у пациентов, которым экстренно вводили нагрузочную дозу калия внутривенно.\u003Cbr /\u003EНестероидные противовоспалительные препараты - риск развития гиперкалиемии вследствие развития вторичного гиперальдостеронизма после ингибирования синтеза простагландинов в почках.\u003Cbr /\u003EГепарин снижает синтез альдостерона, что может приводить к развитию гиперкалиемии, особенно при имеющейся почечной недостаточности или других состояниях, ухудшающих экскрецию калия из организма.\u003Cbr /\u003EВведение препаратов калия не рекомендуется у пациентов с тяжелой и полной блокадой сердца, применяющих одновременно сердечные гликозиды. В случае применения препаратов калия для коррекции гипокалиемии у таких пациентов, требуется тщательный мониторинг.\u003Cbr /\u003EОдновременное применение с инсулином, натрия гидрокарбонатом снижает содержание калия в сыворотке крови.\u003Cbr /\u003EСледующие лекарственные средства, содержащие калий, или предрасполагающие к развитию гиперкалиемии, могут привести к кумуляции калия при одновременном применении с препаратами калия: алискирен, антагонисты рецепторов ангиотензина II, циклоспорин, такролимус.\u003Cbr /\u003EФармацевтически совместим со следующими растворами для внутривенного введения: раствор Рингера в комбинации с глюкозой (декстрозой) для инъекций, раствор Рингера лактата в комбинации с глюкозой (декстрозой) для инъекций, 5% раствор глюкозы (декстрозы) в растворе Рингера лактата для инъекций, раствор глюкозы (декстрозы) в комбинации с натрия хлоридом, 5% раствор глюкозы (декстрозы) в 0,9% растворе натрия хлорида, 2,5%, 5%, 10%, 20% растворы глюкозы (декстрозы) в воде для инъекций, раствор Рингера для инъекций, раствор Рингера лактата для инъекций, 0,45%, 0,9%, 3% растворы натрия хлорида.\u003Cbr /\u003EФармацевтически несовместим при разведении с растворами, содержащими: амикацина сульфат, амфотерицин В, амоксициллин натрия, бензилпенициллин, диазепам, добутамина гидрохлорид, эрготамина тартрат, этопозида с цисплантином и маннитолом, метилпреднизолона натрия сукцинат, фенитоина натрия, прометазина гидрохлорид, натрия нитропруссид, стрептомицина сульфат, маннитол, стерильную жировую эмульсию, содержащую соевое масло и лецитин (данный список не является исчерпывающим)."},{"name":"Регистрационный номер","value":"ЛП-000345"},{"name":"Дата государственной регистрации","value":"07.12.2020"},{"name":"Владелец регистрационного удостоверения","value":"Дальхимфарм","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["34324371:35649313","7893318:13877405"]}}},{"name":"Изготовитель","value":"Дальхимфарм"},{"name":"Фасовщик","value":"Дальхимфарм"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Калия хлорид","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["17796364:18007861"]}}},{"name":"Срок годности","value":"1 г."}]}},"fullSpecsGrouped":{"13814649920191844172":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"кровеносная система"},{"name":"Назначение","value":"аритмия, гипокалиемия"},{"name":"Показания к применению","value":"Гипокалиемия различного генеза, в том числе аритмии, обусловленные гипокалиемией."},{"name":"Противопоказания","value":"- Повышенная чувствительность к компонентам препарата;\u003Cbr /\u003E- гиперкалиемия или гиперхлоремия любой этиологии, полная атриовентрикулярная или внутрижелудочковая блокада;\u003Cbr /\u003E- почечная недостаточность с олигурией или азотемией;\u003Cbr /\u003E- фибрилляция желудочков;\u003Cbr /\u003E- Болезнь Аддисона;\u003Cbr /\u003E- гиперадренализм, ассоциированный с адреногенитальным синдромом;\u003Cbr /\u003E- экстенсивный распад тканей (в т.ч. при тяжелых ожогах);\u003Cbr /\u003E- острая дегидратация;\u003Cbr /\u003E- тепловые судороги;\u003Cbr /\u003E- состояния с повышенной чувствительностью к введению калия (в т.ч. наследственная эпизодическая адинамия или врожденная парамиотония);\u003Cbr /\u003E- сопутствующая терапия солями калия и калийсберегающими диуретиками;\u003Cbr /\u003E- возраст до 18 лет."},{"name":"Состав","value":"Действующее вещество: калия хлорид - 30, 40, 75 или 150 мг\u003Cbr /\u003EВспомогательные вещества: - хлористоводородной кислоты раствор 1М - до pH 3,0-4,0, вода для инъекций - до 1 мл\u003Cbr /\u003EТеоретическая осмолярность:\u003Cbr /\u003E\t\u003Cbr /\u003E805 мОсм/л (30 мг/мл концентрат)\u003Cbr /\u003E\t\u003Cbr /\u003E1074 мОсм/л (40 мг/мл концентрат)\u003Cbr /\u003E\t\u003Cbr /\u003E2013 мОсм/л (75 мг/мл концентрат)\u003Cbr /\u003E\t\u003Cbr /\u003E4026 мОсм/л (150 мг/мл концентрат)."},{"name":"Действующее вещество","value":"Калия хлорид"},{"name":"Способ применения и дозы","value":"Препарат вводят внутривенно капельно только после разведения концентрата в 10 раз.\u003Cbr /\u003E10 мл концентрата калия хлорида 40 мг/мл разводят водой для инъекций в 10 раз (до 100 мл) для получения изотонического раствора (концентрация калия хлорида составит 4 мг/мл или 0,4%) и вводят внутривенно капельно (со скоростью 20-30 капель в минуту).\u003Cbr /\u003EОдновременно за одну инфузию вводят не более 100 мл приготовленного раствора. При необходимости вливание можно повторить, но общая суточная доза не должна превышать 300-500 мл приготовленного раствора с концентрацией калия хлорида 4 мг/мл (0,4%).\u003Cbr /\u003EДля внутривенного капельного введения можно готовить раствор из расчета до 2,5 г калия хлорида в 500 мл изотонического 0,9% раствора натрия хлорида или 5% раствора декстрозы (глюкозы).\u003Cbr /\u003EДля профилактики и лечения эктопических аритмий при инфаркте миокарда - применяется поляризующая смесь: раствор калия хлорида 2-2,5 г в 500 мл 5-10% декстрозы (глюкозы), к которому добавляют инсулин короткого действия из расчета 1 ЕД на 3-4 г сухой декстрозы (глюкозы).\u003Cbr /\u003EДозы\u003Cbr /\u003EДоза для лечения дефицита калия должна быть подобрана в соответствии с фактической концентрацией электролитов в плазме крови и показателей кислотно-основного состояния.\u003Cbr /\u003E1 ммоль калия (К+) соответствует 75 мг калия хлорида (КС1).\u003Cbr /\u003EВзрослые и пожилые пациенты:\u003Cbr /\u003EДоза для лечения умеренного, бессимптомного дефицита калия и при поддерживающей терапии:\u003Cbr /\u003EКоличество калия, необходимое для коррекции умеренного дефицита калия и при поддерживающей терапии может быть рассчитано по следующей формуле:\u003Cbr /\u003Eтребуемое количество ммоль К+=(МТ* [кг] х 0,2)** х 2 х (целевая концентрация К+ в плазме крови***- фактическая концентрация К+ в плазме крови [ммоль/л])\u003Cbr /\u003Eгде:\u003Cbr /\u003E*МТ= масса тела;\u003Cbr /\u003E** значение представляет собой внеклеточный объем жидкости;\u003Cbr /\u003E*** целевая концентрация К+ в плазме крови должна быть равна 4,5 ммоль калия/л.\u003Cbr /\u003EМаксимальная суточная доза (например, в случае тяжелой симптоматической гипокалиемии или значительных потерь):\u003Cbr /\u003EДо 2-3 ммоль калия/кг массы тела.\u003Cbr /\u003EМаксимальная скорость введения:\u003Cbr /\u003EДо 20 ммоль калия/час у взрослых (соответствует 0,3 ммоль калия/кг массы тела /час). Если концентрация калия в плазме крови составляет менее 2 ммоль калия/л, скорость инфузии может достигать 40 ммоль калия/час.\u003Cbr /\u003EПациенты с сахарным диабетом:\u003Cbr /\u003EИзменение кислотно-основного состояния оказывает влияние на концентрацию калия в плазме крови. Потребность в калии увеличивается при компенсации кетоацидоза у пациентов с сахарным диабетом, а также при введении декстрозы/инсулина короткого действия."},{"name":"Побочные действия","value":"Неблагоприятные побочные реакции могут развиться в виде симптомов гиперкалиемии только в случае абсолютной или относительной передозировки и/или слишком высокой скорости инфузии.\u003Cbr /\u003EЧастота развития неблагоприятных побочных реакций зависит от дозы.\u003Cbr /\u003EНарушения со стороны иммунной системы: аллергические реакции.\u003Cbr /\u003EНарушения со стороны обмена веществ и питания: ацидоз, гиперхлоремия, гиперкалиемия.\u003Cbr /\u003EНарушения со стороны нервной системы: утомляемость, мышечная слабость, спутанность сознания, тяжесть в конечностях, мышечные судороги, парестезии, восходящий паралич.\u003Cbr /\u003EНарушения со стороны сердца: брадикардия, AV блокада, фибрилляция желудочков, остановка сердца.\u003Cbr /\u003EСлишком высокая скорость инфузии может вызвать сердечную аритмию.\u003Cbr /\u003EНарушения со стороны сосудов: снижение артериального давления, централизация кровообращения.\u003Cbr /\u003EНарушения со стороны желудочно-кишечного тракта: тошнота."},{"name":"Фармакологическое действие","value":"Механизм действия\u003Cbr /\u003EКалий является важнейшим катионом внутриклеточного пространства, около 98% общего содержания калия в организме находится во внутриклеточной жидкости.\u003Cbr /\u003EКалий участвует в электрохимических процессах клетки, а также в углеводном и белковом обменах. Во время синтеза гликогена и белков калий потребляется клетками, а в процессе расщепления этих субстратов калий высвобождается (около 0,4-1 ммоль калия/г гликогена и около 2-3 ммоль калия/г выводимого азота).\u003Cbr /\u003EТерапевтический эффект\u003Cbr /\u003EТерапевтическим эффектом растворов калия хлорида для внутривенного введения является предотвращение или лечение дефицита калия, когда пероральный прием (или энтеральное введение) невозможен или недостаточен.\u003Cbr /\u003EСуточная потребность в калии составляет около 1-1,5 ммоль/кг массы тела.\u003Cbr /\u003EДефицит калия может быть вызван повышением почечной экскреции, увеличением потерь через желудочно-кишечный тракт, например, при рвоте, диарее или через свищи, повышением внутриклеточного потребления, например, при лечении ацидоза или введении декстрозы и инсулина, а также при недостаточном потреблении калия.\u003Cbr /\u003EГипокалиемия сопровождается мышечной слабостью, атонией гладких мышц желудочно-кишечного тракта (от запора до кишечной непроходимости), потерей способности почек концентрировать мочу, изменениями ЭКГ и сердечной аритмией."},{"name":"Фармакологическая группа","value":"калия препарат"},{"name":"Форма выпуска","value":"концентрат для приготовления раствора для инфузий"},{"name":"Способ применения/введения","value":"парентеральный"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"При температуре не выше 30 °С. Хранить в недоступном для детей месте."},{"name":"Условия отпуска из аптеки","value":"По накладным для ЛПУ."},{"name":"Передозировка","value":"Симптомы: нарушение экскреторного механизма или слишком быстрое внутривенное введение калия может привести к фатальной гиперкалиемии (повышение содержания ионов калия в сыворотке крови выше 5,5 мэкв/л), проявлениями которой являются: мышечный гипотонус, парестезии конечностей, замедление атриовентрикулярной проводимости, аритмии, остановка сердца.\u003Cbr /\u003EРанние изменения электрокардиограммы - высокий зубец Т с заостренной вершиной и узким основанием, наиболее выраженный в грудных отведениях V2-V4 проявляются при повышении концентрации ионов калия в сыворотке крови до 5,5-6,5 мэкв/л. При умеренной гиперкалиемии (содержание ионов калия в сыворотке крови 6,5-8,0 мэкв/л) электрокардиографическими признаками являются: уменьшение амплитуды зубца Р, удлинение интервала QT, расширение комплекса QRS, снижение амплитуды зубца R, желудочковая экстрасистолия.\u003Cbr /\u003EБолее тяжелые симптомы гиперкалиемии - паралич мускулатуры и остановка сердца (изменение на электрокардиограмме - медленный или ускоренный идиовентрикулярный ритм, фибрилляция желудочков, асистолия) развиваются при содержании ионов калия в сыворотке крови 9-14 мэкв/л.\u003Cbr /\u003EЛечение: прекращение инфузии Калия хлорида. Внутрь или внутривенно - раствор натрия хлорида; внутривенно 300-500 мл 5% раствора декстрозы (с 10-20 ЕД инсулина короткого действия на 1 л); коррекция ацидоза (при наличии) с помощью внутривенного введения натрия гидрокарбоната при необходимости - гемодиализ и перитонеальный диализ.\u003Cbr /\u003EАритмия или сывороточная концентрация калия свыше 6,5 ммоль/л требует немедленного лечения с помощью внутривенного введения 10-20 мл 10% раствора кальция глюконата в течение 1-5 минут. При лечении гиперкалиемии у пациентов, находящихся на лечении сердечными гликозидами, быстрое снижение концентрации калия в сыворотке крови может приводить к дигиталисной интоксикации. При лечении передозировки необходимо проводить непрерывный ЭКГ-мониторинг, периодически определять мочевину, электролиты и креатинин в плазме крови, контроль концентрации калия (при необходимости, каждые 2-3 ч), бессимптомных пациентов необходимо наблюдать в течение 6 ч."},{"name":"Применение при беременности и кормлении грудью","value":"При назначении препарата беременным женщинам следует соблюдать осторожность. Препарат должен применяться только при явных показаниях к его применению, если ожидаемая польза для матери превышает потенциальный риск для плода (по возможности назначают препараты калия для приема внутрь).\u003Cbr /\u003EКалий выводится с грудным молоком. При назначении препарата кормящим женщинам следует соблюдать осторожность (по возможности назначают препараты калия для приема внутрь)."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В период лечения препаратом следует соблюдать осторожность при выполнении потенциально опасных видов деятельности, требующих повышенной концентрации внимания и быстроты психомоторных реакций (управление транспортными средствами, работа с движущимися механизмами, работа диспетчера и оператора)."},{"name":"Особые указания","value":"С осторожностью:\u003Cbr /\u003E- Атриовентрикулярная блокада I-II степени, сердечная недостаточность;\u003Cbr /\u003E- серповидноклеточная анемия;\u003Cbr /\u003E- заболевания и состояния, сопровождающиеся нарушением экскреции калия, в т.ч. хроническая почечная недостаточность;\u003Cbr /\u003E- надпочечниковая недостаточность;\u003Cbr /\u003E- У пациентов, принимающих сердечные гликозиды, антагонисты альдостерона, ингибиторы АПФ, такролимус, циклоспорин, гепарин длительного действия, суксаметоний или потенциально нефротоксичные лекарственные препараты (нестероидные противовоспалительные препараты, анальгетики периферического действия).\u003Cbr /\u003EВ период лечения необходимо проводить мониторинг концентрации калия в сыворотке крови во время введения и своевременно корректировать дозу. Кроме того (особенно при заболевании сердца, почек или наличии ацидоза), рекомендуется контроль кислотно-щелочного баланса, электролитов сыворотки, ЭКГ и клинического состояния пациента.\u003Cbr /\u003EГиперкалиемия развивается быстро и протекает бессимптомно и потенциально может привести к блокаде внутрисердечного проведения и летальному исходу. Ранние признаки гиперкалиемии - гипотонус и парестезии конечностей.\u003Cbr /\u003EЛечение гипокалиемии не должно проводится одновременным введением солей калия и калийсберегающих диуретиков во избежание тяжелой гиперкалиемии.\u003Cbr /\u003EЛечение препаратами калия не должно проводится при заболеваниях, сопровождающихся блокадами сердца, поскольку это может повышать степень блокады.\u003Cbr /\u003EНа начальном этапе лечения следует избегать введения одновременно с глюкозой, поскольку это может способствовать дальнейшему снижению концентрации калия.\u003Cbr /\u003EНеобходимо обеспечить исключительно внутривенное введение препарата, поскольку околовенозное введение может вызвать некроз тканей.\u003Cbr /\u003EВведение калия хлорида в вены небольшого диаметра может сопровождаться болезненностью в месте введения.\u003Cbr /\u003EРаствор следует использовать только если он прозрачен и флакон не поврежден.\u003Cbr /\u003EПрепарат применять только разведенным в совместимом растворе для инфузий. Препарат разводить непосредственно после вскрытия флакона. При разведении препарата требуется строгое соблюдение правил асептики.\u003Cbr /\u003EРаствор использовать только если он прозрачен и ампула не повреждена.\u003Cbr /\u003EПрепарат разводить непосредственно после вскрытия ампулы. При разведении препарата требуется строгое соблюдение правил асептики.\u003Cbr /\u003EАмпула только для одноразового использования. Исключение составляют разведения, приготовленные в контролируемых и асептических условиях.\u003Cbr /\u003EС точки зрения микробиологической безопасности разведенный препарат должен быть использован немедленно."},{"name":"Взаимодействие","value":"Одновременное введение с калийсберегающими диуретиками (в т.ч. триамтерен, спиронолактон, амилорид) может привести к тяжелой гиперкалиемии за счет снижения почечной экскреции ионов калия.\u003Cbr /\u003EИнгибиторы АПФ - риск развития гиперкалиемии, поскольку ингибиторы АПФ снижают секрецию альдостерона, что приводит к задержке калия в организме.\u003Cbr /\u003EБета-адреноблокаторы повышали как максимальную концентрацию калия в сыворотке крови, так и время, необходимое для ее возвращения к исходному уровню у пациентов, которым экстренно вводили нагрузочную дозу калия внутривенно.\u003Cbr /\u003EНестероидные противовоспалительные препараты - риск развития гиперкалиемии вследствие развития вторичного гиперальдостеронизма после ингибирования синтеза простагландинов в почках.\u003Cbr /\u003EГепарин снижает синтез альдостерона, что может приводить к развитию гиперкалиемии, особенно при имеющейся почечной недостаточности или других состояниях, ухудшающих экскрецию калия из организма.\u003Cbr /\u003EВведение препаратов калия не рекомендуется у пациентов с тяжелой и полной блокадой сердца, применяющих одновременно сердечные гликозиды. В случае применения препаратов калия для коррекции гипокалиемии у таких пациентов, требуется тщательный мониторинг.\u003Cbr /\u003EОдновременное применение с инсулином, натрия гидрокарбонатом снижает содержание калия в сыворотке крови.\u003Cbr /\u003EСледующие лекарственные средства, содержащие калий, или предрасполагающие к развитию гиперкалиемии, могут привести к кумуляции калия при одновременном применении с препаратами калия: алискирен, антагонисты рецепторов ангиотензина II, циклоспорин, такролимус.\u003Cbr /\u003EФармацевтически совместим со следующими растворами для внутривенного введения: раствор Рингера в комбинации с глюкозой (декстрозой) для инъекций, раствор Рингера лактата в комбинации с глюкозой (декстрозой) для инъекций, 5% раствор глюкозы (декстрозы) в растворе Рингера лактата для инъекций, раствор глюкозы (декстрозы) в комбинации с натрия хлоридом, 5% раствор глюкозы (декстрозы) в 0,9% растворе натрия хлорида, 2,5%, 5%, 10%, 20% растворы глюкозы (декстрозы) в воде для инъекций, раствор Рингера для инъекций, раствор Рингера лактата для инъекций, 0,45%, 0,9%, 3% растворы натрия хлорида.\u003Cbr /\u003EФармацевтически несовместим при разведении с растворами, содержащими: амикацина сульфат, амфотерицин В, амоксициллин натрия, бензилпенициллин, диазепам, добутамина гидрохлорид, эрготамина тартрат, этопозида с цисплантином и маннитолом, метилпреднизолона натрия сукцинат, фенитоина натрия, прометазина гидрохлорид, натрия нитропруссид, стрептомицина сульфат, маннитол, стерильную жировую эмульсию, содержащую соевое масло и лецитин (данный список не является исчерпывающим)."},{"name":"Регистрационный номер","value":"ЛП-000345"},{"name":"Дата государственной регистрации","value":"07.12.2020"},{"name":"Владелец регистрационного удостоверения","value":"Дальхимфарм"},{"name":"Изготовитель","value":"Дальхимфарм"},{"name":"Фасовщик","value":"Дальхимфарм"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Калия хлорид"},{"name":"Срок годности","value":"1 г."}]}],"transitionId":"tr_2006127651800526076"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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85 ₽

  • 19-21 июня, самовывоз • 0 ₽
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  • Саливиттелин капс.
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    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-dwgjp9n2pm/toggleWishlist":{"skuId":"989380008","productId":1781572884,"offerId":"mL0OsG_bqsHq2WNEOBt94g","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ95Oh9o2jr6MWEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYIlMrC0QYQqPvi1wMY3/30BSDX3MEH","sign":"15c+vlaiP8mzuFlv8WbtxOtcAUPDMRx0OXCg+mXrEG0="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-dwgjp9n2pm/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Саливиттелин капс.

    Рейтинг товара: 5 из 5
    на основе 2 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 685 ₽ вместо 699
    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  • Чистые сосуды, капс., 400 мг, 60 г, 60 шт., 1
    –1 %
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    Чистые сосуды, капс., 400 мг, 60 г, 60 шт., 1

    Рейтинг товара: 5 из 5
    на основе 2 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 763 ₽ вместо 771
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  • Марикад капс.
    –22 %
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    Марикад капс.

    С картой  Пэй
    Цена с картой Яндекс Пэй 4 639 ₽ вместо 4 733
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  • Ад Норма капс., 56 г, 60 шт., 1
    –1 %
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    Ад Норма капс., 56 г, 60 шт., 1

    Рейтинг товара: 5 из 5
    на основе 4 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 537 ₽ вместо 542
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  • ЛимфоТранзит концентрат напитка фл., 100 мл
    –1 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-5fyv31y5k4/toggleWishlist":{"skuId":"663078029","productId":1780857920,"offerId":"vvDuYa1NcTP9g5mBuSRxdg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ95Oh9o2jr6MWEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYIwPiW0QYQjYmXvAIY1buhBiDX3MEH","sign":"k/j+RAeiBNCoP36qdp1TQZGquF3ylAb1fh7KrqC1Pls="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-5fyv31y5k4/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    ЛимфоТранзит концентрат напитка фл., 100 мл

    Рейтинг товара: 5 из 5
    на основе 2 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 361 ₽ вместо 365
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  • Антихолестерин таб., 30 шт.
    –14 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-dz4ie1zh625/toggleWishlist":{"skuId":"652150629","productId":1780857894,"offerId":"-UtUKk1nwdr3wawHRg_PLQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ95Oh9o2jr6MWEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYIpviW0QYQ5Y78tgIYmuuGESDX3MEH","sign":"dWCBJYZD7/kdc5lxM/O7kU59hc9IyQMxC0/QwCF4tec="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-dz4ie1zh625/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Антихолестерин таб., 30 шт.

    Рейтинг товара: 4.3 из 5
    на основе 15 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 241 ₽ вместо 243
    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таб., 30 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  • Ад минус таб., 40 шт.
    –1 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-8s108ruh3rr/toggleWishlist":{"skuId":"226177677","productId":1778173791,"offerId":"4l2lSyhPkC3V5o1As7TOkg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ95Oh9o2jr6MWEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI347zzwYQjeXsaxjVu6EGINfcwQc=","sign":"DCLxnJJQyXrpuVEw5JF4wjZMuuXc6NNgRju4pCStnKw="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-8s108ruh3rr/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Ад минус таб., 40 шт.

    Рейтинг товара: 5 из 5
    на основе 5 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 487 ₽ вместо 492
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  • Атеролип капс., 30 шт., 1
    –23 %
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    Атеролип капс., 30 шт., 1

    Рейтинг товара: 4.8 из 5
    на основе 137 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 1 225 ₽ вместо 1 249
    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  • Элларга пор., 3 г
    –5 %
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    Элларга пор., 3 г

    Цена 1 496 ₽ вместо 1 575
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  • Вентфорт капс., 4 г, 20 шт., 1
    –23 %
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    Вентфорт капс., 4 г, 20 шт., 1

    Рейтинг товара: 4.7 из 5
    на основе 18 оценок
    Цена 1 900 ₽ вместо 2 470
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Инструкция

Показания к применению

Гипокалиемия различного генеза, в том числе аритмии, обусловленные гипокалиемией.

Противопоказания

- Повышенная чувствительность к компонентам препарата;
- гиперкалиемия или гиперхлоремия любой этиологии, полная атриовентрикулярная или внутрижелудочковая блокада;
- почечная недостаточность с олигурией или азотемией;
- фибрилляция желудочков;
- Болезнь Аддисона;
- гиперадренализм, ассоциированный с адреногенитальным синдромом;
- экстенсивный распад тканей (в т.ч. при тяжелых ожогах);
- острая дегидратация;
- тепловые судороги;
- состояния с повышенной чувствительностью к введению калия (в т.ч. наследственная эпизодическая адинамия или врожденная парамиотония);
- сопутствующая терапия солями калия и калийсберегающими диуретиками;
- возраст до 18 лет.

Способ применения и дозы

Препарат вводят внутривенно капельно только после разведения концентрата в 10 раз.
10 мл концентрата калия хлорида 40 мг/мл разводят водой для инъекций в 10 раз (до 100 мл) для получения изотонического раствора (концентрация калия хлорида составит 4 мг/мл или 0,4%) и вводят внутривенно капельно (со скоростью 20-30 капель в минуту).
Одновременно за одну инфузию вводят не более 100 мл приготовленного раствора. При необходимости вливание можно повторить, но общая суточная доза не должна превышать 300-500 мл приготовленного раствора с концентрацией калия хлорида 4 мг/мл (0,4%).
Для внутривенного капельного введения можно готовить раствор из расчета до 2,5 г калия хлорида в 500 мл изотонического 0,9% раствора натрия хлорида или 5% раствора декстрозы (глюкозы).
Для профилактики и лечения эктопических аритмий при инфаркте миокарда - применяется поляризующая смесь: раствор калия хлорида 2-2,5 г в 500 мл 5-10% декстрозы (глюкозы), к которому добавляют инсулин короткого действия из расчета 1 ЕД на 3-4 г сухой декстрозы (глюкозы).
Дозы
Доза для лечения дефицита калия должна быть подобрана в соответствии с фактической концентрацией электролитов в плазме крови и показателей кислотно-основного состояния.
1 ммоль калия (К+) соответствует 75 мг калия хлорида (КС1).
Взрослые и пожилые пациенты:
Доза для лечения умеренного, бессимптомного дефицита калия и при поддерживающей терапии:
Количество калия, необходимое для коррекции умеренного дефицита калия и при поддерживающей терапии может быть рассчитано по следующей формуле:
требуемое количество ммоль К+=(МТ* [кг] х 0,2)** х 2 х (целевая концентрация К+ в плазме крови***- фактическая концентрация К+ в плазме крови [ммоль/л])
где:
*МТ= масса тела;
** значение представляет собой внеклеточный объем жидкости;
*** целевая концентрация К+ в плазме крови должна быть равна 4,5 ммоль калия/л.
Максимальная суточная доза (например, в случае тяжелой симптоматической гипокалиемии или значительных потерь):
До 2-3 ммоль калия/кг массы тела.
Максимальная скорость введения:
До 20 ммоль калия/час у взрослых (соответствует 0,3 ммоль калия/кг массы тела /час). Если концентрация калия в плазме крови составляет менее 2 ммоль калия/л, скорость инфузии может достигать 40 ммоль калия/час.
Пациенты с сахарным диабетом:
Изменение кислотно-основного состояния оказывает влияние на концентрацию калия в плазме крови. Потребность в калии увеличивается при компенсации кетоацидоза у пациентов с сахарным диабетом, а также при введении декстрозы/инсулина короткого действия.
Полная инструкция
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Калия хлорид конц. д/приг. р-ра д/инф.
Калия хлорид конц. д/приг. р-ра д/инф., 40 мг/мл, 10 мл, 10 шт.
5.0
(2)
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Инструкция

85 ₽

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5.0
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Рекомендуем

  • Саливиттелин капс.
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    Саливиттелин капс.

    Цена 685 ₽ вместо 1 189
  • Чистые сосуды, капс., 400 мг, 60 г, 60 шт., 1
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    Чистые сосуды, капс., 400 мг, 60 г, 60 шт., 1

    Цена 763 ₽ вместо 771
  • Марикад капс.
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    Марикад капс.

    Цена 4 639 ₽ вместо 5 917
  • Ад Норма капс., 56 г, 60 шт., 1
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    Ад Норма капс., 56 г, 60 шт., 1

    Цена 537 ₽ вместо 542
  • ЛимфоТранзит концентрат напитка фл., 100 мл
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    ЛимфоТранзит концентрат напитка фл., 100 мл

    Цена 361 ₽ вместо 365
  • Антихолестерин таб., 30 шт.
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    Антихолестерин таб., 30 шт.

    Цена 241 ₽ вместо 280
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