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Описание

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Кловейт мазь, 0,05%, 25 мл, 25 г

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4.5
(34)
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Коротко о товаре

Артикул Маркета
3509994780
Тип препарата
Назначение
Действующее вещество
Возраст
от 1 года
Инструкция
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дерматозы, трудно поддающиеся лечению;\u003Cbr /\u003E- красный плоский лишай;\u003Cbr /\u003E- дискоидная красная волчанка;\u003Cbr /\u003E- другие заболевания кожи, устойчивые к терапии менее сильными глюкокортикостероидами.\u003Cbr /\u003E"},{"name":"Противопоказания","value":"- повышенная чувствительность к клобетазолу (или любым другим глюкокортикостероидам) или любому другому компоненту, входящему в состав препарата:\u003Cbr /\u003E- нелеченые инфекции кожи;\u003Cbr /\u003E- розовые угри (розацеа);\u003Cbr /\u003E- акне;\u003Cbr /\u003E- периоральный дерматит;\u003Cbr /\u003E- кожный зуд в отсутствие воспаления;\u003Cbr /\u003E- перианальный и генитальный зуд;\u003Cbr /\u003E- детский возраст до 1 года;\u003Cbr /\u003E- период грудного вскармливания.\u003Cbr /\u003E"},{"name":"Состав","value":"Действующее вещество: клобетазола пропионат - 500 мкг.\u003Cbr\u003EВспомогательные вещества: пропиленгликоль - 50 мг, сорбитана сесквиолеат - 5 мг, вазелин белый - до 1 г.\u003Cbr/\u003E"},{"name":"Действующее вещество","value":"Клобетазол","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-kozhi","categoryId":"15756517","navnodeId":"25025070","glfilters":["27144131:28708234"]}}},{"name":"Способ применения и дозы","value":"Наружно.\u003Cbr /\u003EМазь рекомендуется применять при поражениях кожи, сопровождающихся ее сухостью, гиперкератозом и утолщением.\u003Cbr /\u003EВзрослым, лицам пожичого возраста и детям старше года\u003Cbr /\u003EПрепарат следует наносить тонким слоем и осторожно втирать, применяя в минимальных количествах, достаточных для покрытия всего пораженного участка 1 или 2 раза в сутки до улучшения состояния, затем следует снизить частоту нанесения или заменить препарат на менее сильный. После каждого применения препарат необходимо оставить на достаточное время для впитывания перед нанесением смягчающего средства.\u003Cbr /\u003EДля предупреждения обострений кожных заболеваний проводят короткие (прерывистые) курсы лечения препаратом Кловейт.\u003Cbr /\u003EПри более стойких поражениях, особенно при наличии гиперкератоза, действие мази для наружного применения Кловейт при необходимости может быть усилено путем наложения окклюзионной повязки из полиэтиленовой пленки на место лечения. Обычно для получения удовлетворительного ответа достаточным является наложение окклюзионной повязки на ночь. В дальнейшем улучшение обычно удается поддерживать с помощью нанесения препарата без повязки. Если в течение 2—4 недель состояние ухудшается или не улучшается, следует провести повторную оценку диагноза и лечения.\u003Cbr /\u003EЛечение не должно продолжаться более 4 недель. Если необходимо продолжение лечения, следует применять менее сильный препарат. Максимальная доза не должна превышать 50 г мази в неделю.\u003Cbr /\u003EЛечение препаратом Кловейт следует постепенно отменять после достижения контроля над заболеванием, а лечение смягчающим средством должно быть продолжено в качестве поддерживающей терапии.\u003Cbr /\u003EРезкая отмена препарата Кловейт может приводить к рецидиву ранее имевшихся дерматозов.\u003Cbr /\u003EДерматозы, трудно поддающиеся лечению: пациенты с частыми рецидивами заболевания\u003Cbr /\u003EВ случае острого заболевания, как только будет достигнут эффект от непрерывного курса лечения препаратом Кловейт, может быть рассмотрена возможность прерывистого режима применения препарата (один раз в сутки, два раза в неделю, без окклюзионной повязки). Показано, что такое лечение эффективно снижает частоту развития рецидивов.\u003Cbr /\u003EНанесение препарата должно быть продолжено на все ранее пораженные участки кожи или на известные области потенциального обострения. Такая схема применения должна сочетаться с рутинным ежедневным применением смягчающих средств. Следует проводить регулярную оценку состояния пациента, а также пользы и риска от продолжения лечения.\u003Cbr /\u003EОсобые группы пациентов\u003Cbr /\u003EДети\u003Cbr /\u003EПрепарат Кловейт, мазь для наружного применения противопоказан у детей в возрасте до 1 года.\u003Cbr /\u003EУ детей более вероятно развитие местных и системных побочных эффектов при терапии глюкокортикостероидами для наружного применения и, как правило, им требуется проведение более коротких курсов лечения с использованием менее активных средств, чем у взрослых.\u003Cbr /\u003EСледует соблюдать осторожность при использовании препарата Кловейт у детей, чтобы обеспечить нанесение препарата в минимальном количестве, обеспечивающем терапевтический эффект.\u003Cbr /\u003EКурс лечения у детей должен ограничиваться, по возможности, пятью днями; требуется наблюдение у врача не реже одного раза в неделю. Окклюзионные повязки не должны применяться.\u003Cbr /\u003EПациенты пожилого возраста\u003Cbr /\u003EКлинические исследования не выявили каких-либо различий в эффективности препарата у пожилых и более молодых пациентов. Большая распространенность сниженной функции печени или почек у пациентов пожилого возраста может приводить к замедлению выведения препарата в случае его системной абсорбции. Следовательно, препарат должен применяться в минимальном количестве и в течение как можно более короткого периода, до достижения необходимого клинического эффекта.\u003Cbr /\u003EПациенты с нарушением функции почек и/или печени\u003Cbr /\u003EВ случае системной абсорбции препарата (при нанесении на обширные поверхности кожи в течение продолжительного периода) его метаболизм и выведение могут замедляться, приводя к повышенному риску развития системных побочных эффектов. Следовательно, препарат должен применяться в минимальном количестве и в течение как можно более короткого периода, до достижения необходимого клинического эффекта.\u003Cbr /\u003EПрименение в области лица\u003Cbr /\u003EПрименение в области лица нежелательно, так как эта область более восприимчива к атрофическим изменениям.\u003Cbr /\u003EКурс лечения должен ограничиваться, если это возможно, пятью днями. Окклюзионные повязки не должны применяться.\u003Cbr /\u003E"},{"name":"Побочные действия","value":"Частота возникновения побочных реакций классифицирована в соответствии с рекомендациями Всемирной Организацией Здравоохранения (ВОЗ), побочные эффекты классифицированы по частоте:\u003Cbr /\u003Eочень часто (≥1/10), часто (≥1/100 и \u003C 1/10), нечасто (≥1/1000 и \u003C 1/100), редко (≥1/10000 и \u003C 1/1000), очень редко (\u003C 1/10000, включая отдельные случаи), частота неизвестна (невозможно оценить по доступным данным).\u003Cbr /\u003EИнфекционные и паразитарные заболевания. Очень редко: оппортунистические инфекции.\u003Cbr /\u003EНарушения со стороны иммунной системы\u003Cbr /\u003EОчень редко: повышенная гиперчувствительность, генерализованная сыпь.\u003Cbr /\u003EНарушения со стороны эндокринной системы\u003Cbr /\u003EОчень редко: угнетение гипоталамо-гипофизарно-надпочечниковой системы, синдром Иценко-Кушинга (синдром гиперкортицизма) (например, лунообразное лицо, ожирение по центральному типу), задержка прибавки массы тела и/или задержка роста у детей, остеопороз, глаукома, гипергликемия и/или глюкозурия, катаракта, повышение артериального давления, повышение массы тела или ожирение, снижение концентрации эндогенного кортизола, алопеция, ломкость волос.\u003Cbr /\u003EСо стороны кожи и подкожных тканей\u003Cbr /\u003EЧасто: зуд, чувство жжения и/или болезненность.\u003Cbr /\u003EНечасто: местная атрофия кожи*, стрии*, телеангиэктазии*.\u003Cbr /\u003EОчень редко: истончение кожи*, морщинистость кожи*, сухость кожи*, изменение пигментации*, гипертрихоз, усугубление симптомов заболевания, аллергический контактный дерматит и/или дерматит, пустулезный псориаз, эритема, сыпь, крапивница, акне.\u003Cbr /\u003EСо стороны органа зрения\u003Cbr /\u003EЧастота неизвестна: снижение остроты зрения.\u003Cbr /\u003EВ случае применения лекарственного препарата на коже век иногда может развиться глаукома или катаракта, а в редких случаях - центральная серозная хориоретинопатия (ЦСХ).\u003Cbr /\u003EОбщие расстройства и нарушения в месте введения\u003Cbr /\u003EОчень редко: раздражение и/или болезненность в месте нанесения.\u003Cbr /\u003E*Кожные проявления вторичны по отношению к местным и/или системным эффектам угнетения гипоталамо-гипофизарно-надпочечниковой системы.\u003Cbr /\u003E"},{"name":"Фармакологическое действие","value":"Глюкокортикостероид для наружного применения. Предупреждает краевое скопление нейтрофилов, уменьшает воспалительную экссудацию и продукцию лимфокинов, тормозит миграцию макрофагов, снижает интенсивность процессов инфильтрации и грануляции, оказывает местный противовоспалительный, противозудный, противоаллергический и антиэкссудативный эффекты."},{"name":"Фармакологическая группа","value":"глюкокортикостероиды"},{"name":"Форма выпуска","value":"мазь"},{"name":"Способ применения/введения","value":"наружный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-kozhi","categoryId":"15756517","navnodeId":"25025070","glfilters":["35947170:36763741"]}}},{"name":"Минимальный возраст применения","value":"от 1 года"},{"name":"Условия хранения","value":"Хранить при температуре не выше 25 °С. \nХранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы: препарат Кловейт при наружном применении может абсорбироваться в количествах, достаточных для того, чтобы вызвать развитие системных эффектов. Развитие острой передозировки маловероятно. Однако в случае хронической передозировки или неправильного применения препарата Кловейт могут развиться симптомы гиперкортицизма.\u003Cbr /\u003EЛечение: в случае передозировки препарат следует постепенно отменять, снижая частоту его нанесения или заменяя менее активным глюкокортикостероидом, под наблюдением врача ввиду риска возникновения надпочечниковой недостаточности.\u003Cbr /\u003EДальнейшее лечение следует проводить с учетом клинической ситуации.\u003Cbr /\u003E"},{"name":"Применение при беременности и кормлении грудью","value":"Фертильность\u003Cbr /\u003EДанные для оценки влияния глюкокортикостероидов для наружного применения на фертильность у человека отсутствуют.\u003Cbr /\u003EПри подкожном введении крысам клобетазол не оказывал влияния на способность к спариванию, однако при его применении в самой высокой дозе было отмечено снижение фертильности.\u003Cbr /\u003EБеременность\u003Cbr /\u003EДанные о применении клобетазола у беременных женщин ограничены.\u003Cbr /\u003EНаружное применение глюкокортикостероидов у беременных животных может вызвать нарушение развития плода. Значение этих данных для человека не установлено.\u003Cbr /\u003EПрименение клобетазола во время беременности возможно только в том случае, если ожидаемая польза для матери превосходит потенциальный риск для плода. В случае назначения препарата во время беременности - следует применять минимальное количество мази на протяжении минимального периода времени.\u003Cbr /\u003EПериод грудного вскармливания\u003Cbr /\u003EПрименение препарата в период грудного вскармливания противопоказано.\u003Cbr /\u003E"},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Исследования по изучению влияния клобетазола на способность к управлению транспортными средствами или работе с механизмами не проводились. Исходя из профиля побочных реакций клобетазола для наружного применения, какоелибо неблагоприятное влияние на такие виды деятельности не ожидается."},{"name":"Особые указания","value":"С осторожностью: повышенная местная чувствительность к глюкокортикостероидам или к любому вспомогательному веществу, входящему в состав препарата; псориаз; детский возраст от года до 18 лет.\u003Cbr /\u003EМестные реакции повышенной чувствительности (см. раздел «Побочное действие») могут иметь сходство с симптомами протекающего заболевания.\u003Cbr /\u003EУ некоторых пациентов в результате повышенной системной абсорбции глюкокортикостероидов для наружного применения могут возникать проявления гиперкортицизма (синдрома Иценко-Кушинга) и обратимое угнетение гипоталамо-гипофизарно-надпочечниковой системы, ведущее к развитию глюкокортикостероидной недостаточности. Если наблюдается любое из вышеуказанных нарушений, следует отменить препарат, постепенно уменьшая частоту его нанесения, или заменить менее активным глюкокортикостероидом. Резкое прекращение лечения может привести к развитию глюкокортикостероидной недостаточности.\u003Cbr /\u003EВо время терапии препаратом необходим периодический контроль функции коры надпочечников, с помощью определения уровня кортизола в крови и моче после стимуляции надпочечников адренокортикотропным гормоном (АКТГ).\u003Cbr /\u003EК факторам риска усиления системных эффектов относятся: активность глюкокортикостероида и состав лекарственного препарата для наружного применения, продолжительность применения, нанесение препарата на обширные участки кожи, применение в закрытых областях кожи (например, на участках с опрелостью или под окклюзионной повязкой (пеленки и подгузники у младенцев могут играть роль окклюзионной повязки)), повышенное увлажнение рогового слоя кожи, использование на областях с тонкой кожей, таких, как лицо; нанесение на поврежденную кожу или при других состояниях, которые могут сопровождаться нарушением целостности кожного барьера.\u003Cbr /\u003EПрименение у детей\u003Cbr /\u003EСледует применять с осторожностью мазь Кловейт, особенно в качестве длительной терапии, у детей старше одного года, поскольку у данной группы пациентов из-за более высокого соотношения площади поверхности тела к массе тела, чем у взрослых, может всасываться пропорционально большее количество глюкортикостероидов, быстрее развиться нарушение функции гипоталамогипофизарно-надпочечниковой системы и возникнуть системные нежелательные эффекты, характерные для глюкортикостероидов, в том числе задержка роста и развития.\u003Cbr /\u003EПо возможности следует избегать лечения глюкокортикостероидами для наружного применения в течение продолжительного времени у детей младше 12 лет, так как длительное наружное применение глюкокортикостероидов может вызвать угнетение функции надпочечников.\u003Cbr /\u003EУ детей чаще, чем у взрослых, возникают атрофические изменения кожи при наружном применении глюкокортикостероидов. При назначении терапии клобетазола детям - курс лечения должен ограничиваться пятью днями, также требуется наблюдение у врача не реже одного раза в неделю. Не применять окклюзионные повязки.\u003Cbr /\u003EПрименение при псориазе\u003Cbr /\u003EС особой осторожностью следует применять препарат Кловейт у пациентов с псориазом, вследствие возможного рецидива заболевания, вызванного развитием толерантности, риска возникновения генерализованного пустулезного псориаза и развитие местных или системных токсических реакций вследствие нарушения барьерной функции кожи.\u003Cbr /\u003EПациенты с псориазом должны находится под наблюдением врача при терапии мазью Кловейт.\u003Cbr /\u003EСопутствующая инфекция\u003Cbr /\u003EВ случае развития вторичной бактериальной или грибковой инфекции необходимо назначить наружное применение антибактериального или противогрибкового препарата. Если симптомы инфекции распространяются, следует прекратить применение лекарственного препарата Кловейт до излечения инфекции.\u003Cbr /\u003EРиск развития инфекции при окклюзии\u003Cbr /\u003EТеплые, влажные условия в складках кожи, а также условия, создаваемые при наложении окклюзионной повязки, способствуют развитию бактериальной инфекции. При использовании окклюзионной повязки следует очищать кожу перед наложением новой повязки.\u003Cbr /\u003EХронические язвы голеней\u003Cbr /\u003EГлюкокортикостероиды для наружного применения в ряде случаев применяются для лечения дерматита вокруг хронических язв голеней. Однако такое применение может сопровождаться повышенной частотой возникновения местных реакций гиперчувствительности и повышенным риском развития местных инфекций.\u003Cbr /\u003EПрименение на коже лица и веках\u003Cbr /\u003EПоскольку кожа лица более подвержена развитию атрофических изменений применение препарата Кловейт — нежелательно. При назначении — терапия не более 5-ти дней.\u003Cbr /\u003EС осторожностью препарат Кловейт наносят на кожу вокруг глаз или веки с связи с риском развития глаукомы или катаракты, а также у пациентов с этими заболеваниями в анамнезе, у которых может наступить обострение течения этих заболеваний.\u003Cbr /\u003EСледует избегать попадания мази Кловейт в глаза и на слизистые оболочки. При случайном попадании препарата в глаза необходимо обильно промыть их водой.\u003Cbr /\u003EРиск развития центральной серозной хориоретинопатии\u003Cbr /\u003EЕсли у пациента возникают такие симптомы, как нечёткость зрения, либо другие зрительные нарушения, следует рассмотреть возможность направления пациента к офтальмологу для выяснения возможных причин нарушений, к которым может относиться катаракта, глаукома или редкие заболевания, такие как центральная серозная хориоретинопатия.\u003Cbr /\u003EПрименение у пожилых пациентов\u003Cbr /\u003EСледует с осторожностью применять препарат при уже имеющихся атрофических изменениях подкожной клетчатки, особенно у лиц пожилого возраста.\u003Cbr /\u003E"},{"name":"Взаимодействие","value":"Показано, что одновременное применение препаратов, способных ингибировать изофермент СYРЗА4 (например, ритонавир и итраконазол), угнетает метаболизм глюкокортикостероидов, приводя к повышению их системной экспозиции. Степень клинической значимости данного взаимодействия зависит от дозы и способа применения глюкокортикостероидов и активности ингибитора изофермента СYРЗА4."},{"name":"Регистрационный номер","value":"ЛCP-000767/10"},{"name":"Дата государственной регистрации","value":"12.03.2021"},{"name":"Владелец регистрационного удостоверения","value":"Bausch Health","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-kozhi","categoryId":"15756517","navnodeId":"25025070","glfilters":["34324371:35649313","7893318:35809850"]}}},{"name":"Изготовитель","value":"Jelfa"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Польша"},{"name":"Название препарата","value":"Кловейт","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-kozhi","categoryId":"15756517","navnodeId":"25025070","glfilters":["17796364:17882551"]}}},{"name":"Срок годности","value":"24 мес."}]}},"fullSpecsGrouped":{"4940884845912783344":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"кожа"},{"name":"Назначение","value":"дискоидная красная волчанка, плоский лишай, псориаз, экзема"},{"name":"Показания к применению","value":"Клобетазол является очень сильным глюкокортикостероидом, показан для краткосрочного лечения симптомов воспаления и кожного зуда при дерматозах, чувствительных к терапии глюкокортикостероидами, и при невосприимчивости к менее сильным глюкокортикостероидам (для взрослых, лиц пожилого возраста и детей старше года):\u003Cbr /\u003E- псориаз (за исключением широко распространенного бляшечного псориаза); дерматозы, трудно поддающиеся лечению;\u003Cbr /\u003E- красный плоский лишай;\u003Cbr /\u003E- дискоидная красная волчанка;\u003Cbr /\u003E- другие заболевания кожи, устойчивые к терапии менее сильными глюкокортикостероидами.\u003Cbr /\u003E"},{"name":"Противопоказания","value":"- повышенная чувствительность к клобетазолу (или любым другим глюкокортикостероидам) или любому другому компоненту, входящему в состав препарата:\u003Cbr /\u003E- нелеченые инфекции кожи;\u003Cbr /\u003E- розовые угри (розацеа);\u003Cbr /\u003E- акне;\u003Cbr /\u003E- периоральный дерматит;\u003Cbr /\u003E- кожный зуд в отсутствие воспаления;\u003Cbr /\u003E- перианальный и генитальный зуд;\u003Cbr /\u003E- детский возраст до 1 года;\u003Cbr /\u003E- период грудного вскармливания.\u003Cbr /\u003E"},{"name":"Состав","value":"Действующее вещество: клобетазола пропионат - 500 мкг.\u003Cbr\u003EВспомогательные вещества: пропиленгликоль - 50 мг, сорбитана сесквиолеат - 5 мг, вазелин белый - до 1 г.\u003Cbr/\u003E"},{"name":"Действующее вещество","value":"Клобетазол"},{"name":"Способ применения и дозы","value":"Наружно.\u003Cbr /\u003EМазь рекомендуется применять при поражениях кожи, сопровождающихся ее сухостью, гиперкератозом и утолщением.\u003Cbr /\u003EВзрослым, лицам пожичого возраста и детям старше года\u003Cbr /\u003EПрепарат следует наносить тонким слоем и осторожно втирать, применяя в минимальных количествах, достаточных для покрытия всего пораженного участка 1 или 2 раза в сутки до улучшения состояния, затем следует снизить частоту нанесения или заменить препарат на менее сильный. После каждого применения препарат необходимо оставить на достаточное время для впитывания перед нанесением смягчающего средства.\u003Cbr /\u003EДля предупреждения обострений кожных заболеваний проводят короткие (прерывистые) курсы лечения препаратом Кловейт.\u003Cbr /\u003EПри более стойких поражениях, особенно при наличии гиперкератоза, действие мази для наружного применения Кловейт при необходимости может быть усилено путем наложения окклюзионной повязки из полиэтиленовой пленки на место лечения. Обычно для получения удовлетворительного ответа достаточным является наложение окклюзионной повязки на ночь. В дальнейшем улучшение обычно удается поддерживать с помощью нанесения препарата без повязки. Если в течение 2—4 недель состояние ухудшается или не улучшается, следует провести повторную оценку диагноза и лечения.\u003Cbr /\u003EЛечение не должно продолжаться более 4 недель. Если необходимо продолжение лечения, следует применять менее сильный препарат. Максимальная доза не должна превышать 50 г мази в неделю.\u003Cbr /\u003EЛечение препаратом Кловейт следует постепенно отменять после достижения контроля над заболеванием, а лечение смягчающим средством должно быть продолжено в качестве поддерживающей терапии.\u003Cbr /\u003EРезкая отмена препарата Кловейт может приводить к рецидиву ранее имевшихся дерматозов.\u003Cbr /\u003EДерматозы, трудно поддающиеся лечению: пациенты с частыми рецидивами заболевания\u003Cbr /\u003EВ случае острого заболевания, как только будет достигнут эффект от непрерывного курса лечения препаратом Кловейт, может быть рассмотрена возможность прерывистого режима применения препарата (один раз в сутки, два раза в неделю, без окклюзионной повязки). Показано, что такое лечение эффективно снижает частоту развития рецидивов.\u003Cbr /\u003EНанесение препарата должно быть продолжено на все ранее пораженные участки кожи или на известные области потенциального обострения. Такая схема применения должна сочетаться с рутинным ежедневным применением смягчающих средств. Следует проводить регулярную оценку состояния пациента, а также пользы и риска от продолжения лечения.\u003Cbr /\u003EОсобые группы пациентов\u003Cbr /\u003EДети\u003Cbr /\u003EПрепарат Кловейт, мазь для наружного применения противопоказан у детей в возрасте до 1 года.\u003Cbr /\u003EУ детей более вероятно развитие местных и системных побочных эффектов при терапии глюкокортикостероидами для наружного применения и, как правило, им требуется проведение более коротких курсов лечения с использованием менее активных средств, чем у взрослых.\u003Cbr /\u003EСледует соблюдать осторожность при использовании препарата Кловейт у детей, чтобы обеспечить нанесение препарата в минимальном количестве, обеспечивающем терапевтический эффект.\u003Cbr /\u003EКурс лечения у детей должен ограничиваться, по возможности, пятью днями; требуется наблюдение у врача не реже одного раза в неделю. Окклюзионные повязки не должны применяться.\u003Cbr /\u003EПациенты пожилого возраста\u003Cbr /\u003EКлинические исследования не выявили каких-либо различий в эффективности препарата у пожилых и более молодых пациентов. Большая распространенность сниженной функции печени или почек у пациентов пожилого возраста может приводить к замедлению выведения препарата в случае его системной абсорбции. Следовательно, препарат должен применяться в минимальном количестве и в течение как можно более короткого периода, до достижения необходимого клинического эффекта.\u003Cbr /\u003EПациенты с нарушением функции почек и/или печени\u003Cbr /\u003EВ случае системной абсорбции препарата (при нанесении на обширные поверхности кожи в течение продолжительного периода) его метаболизм и выведение могут замедляться, приводя к повышенному риску развития системных побочных эффектов. Следовательно, препарат должен применяться в минимальном количестве и в течение как можно более короткого периода, до достижения необходимого клинического эффекта.\u003Cbr /\u003EПрименение в области лица\u003Cbr /\u003EПрименение в области лица нежелательно, так как эта область более восприимчива к атрофическим изменениям.\u003Cbr /\u003EКурс лечения должен ограничиваться, если это возможно, пятью днями. Окклюзионные повязки не должны применяться.\u003Cbr /\u003E"},{"name":"Побочные действия","value":"Частота возникновения побочных реакций классифицирована в соответствии с рекомендациями Всемирной Организацией Здравоохранения (ВОЗ), побочные эффекты классифицированы по частоте:\u003Cbr /\u003Eочень часто (≥1/10), часто (≥1/100 и \u003C 1/10), нечасто (≥1/1000 и \u003C 1/100), редко (≥1/10000 и \u003C 1/1000), очень редко (\u003C 1/10000, включая отдельные случаи), частота неизвестна (невозможно оценить по доступным данным).\u003Cbr /\u003EИнфекционные и паразитарные заболевания. Очень редко: оппортунистические инфекции.\u003Cbr /\u003EНарушения со стороны иммунной системы\u003Cbr /\u003EОчень редко: повышенная гиперчувствительность, генерализованная сыпь.\u003Cbr /\u003EНарушения со стороны эндокринной системы\u003Cbr /\u003EОчень редко: угнетение гипоталамо-гипофизарно-надпочечниковой системы, синдром Иценко-Кушинга (синдром гиперкортицизма) (например, лунообразное лицо, ожирение по центральному типу), задержка прибавки массы тела и/или задержка роста у детей, остеопороз, глаукома, гипергликемия и/или глюкозурия, катаракта, повышение артериального давления, повышение массы тела или ожирение, снижение концентрации эндогенного кортизола, алопеция, ломкость волос.\u003Cbr /\u003EСо стороны кожи и подкожных тканей\u003Cbr /\u003EЧасто: зуд, чувство жжения и/или болезненность.\u003Cbr /\u003EНечасто: местная атрофия кожи*, стрии*, телеангиэктазии*.\u003Cbr /\u003EОчень редко: истончение кожи*, морщинистость кожи*, сухость кожи*, изменение пигментации*, гипертрихоз, усугубление симптомов заболевания, аллергический контактный дерматит и/или дерматит, пустулезный псориаз, эритема, сыпь, крапивница, акне.\u003Cbr /\u003EСо стороны органа зрения\u003Cbr /\u003EЧастота неизвестна: снижение остроты зрения.\u003Cbr /\u003EВ случае применения лекарственного препарата на коже век иногда может развиться глаукома или катаракта, а в редких случаях - центральная серозная хориоретинопатия (ЦСХ).\u003Cbr /\u003EОбщие расстройства и нарушения в месте введения\u003Cbr /\u003EОчень редко: раздражение и/или болезненность в месте нанесения.\u003Cbr /\u003E*Кожные проявления вторичны по отношению к местным и/или системным эффектам угнетения гипоталамо-гипофизарно-надпочечниковой системы.\u003Cbr /\u003E"},{"name":"Фармакологическое действие","value":"Глюкокортикостероид для наружного применения. Предупреждает краевое скопление нейтрофилов, уменьшает воспалительную экссудацию и продукцию лимфокинов, тормозит миграцию макрофагов, снижает интенсивность процессов инфильтрации и грануляции, оказывает местный противовоспалительный, противозудный, противоаллергический и антиэкссудативный эффекты."},{"name":"Фармакологическая группа","value":"глюкокортикостероиды"},{"name":"Форма выпуска","value":"мазь"},{"name":"Способ применения/введения","value":"наружный"},{"name":"Минимальный возраст применения","value":"от 1 года"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"Хранить при температуре не выше 25 °С. \nХранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы: препарат Кловейт при наружном применении может абсорбироваться в количествах, достаточных для того, чтобы вызвать развитие системных эффектов. Развитие острой передозировки маловероятно. Однако в случае хронической передозировки или неправильного применения препарата Кловейт могут развиться симптомы гиперкортицизма.\u003Cbr /\u003EЛечение: в случае передозировки препарат следует постепенно отменять, снижая частоту его нанесения или заменяя менее активным глюкокортикостероидом, под наблюдением врача ввиду риска возникновения надпочечниковой недостаточности.\u003Cbr /\u003EДальнейшее лечение следует проводить с учетом клинической ситуации.\u003Cbr /\u003E"},{"name":"Применение при беременности и кормлении грудью","value":"Фертильность\u003Cbr /\u003EДанные для оценки влияния глюкокортикостероидов для наружного применения на фертильность у человека отсутствуют.\u003Cbr /\u003EПри подкожном введении крысам клобетазол не оказывал влияния на способность к спариванию, однако при его применении в самой высокой дозе было отмечено снижение фертильности.\u003Cbr /\u003EБеременность\u003Cbr /\u003EДанные о применении клобетазола у беременных женщин ограничены.\u003Cbr /\u003EНаружное применение глюкокортикостероидов у беременных животных может вызвать нарушение развития плода. Значение этих данных для человека не установлено.\u003Cbr /\u003EПрименение клобетазола во время беременности возможно только в том случае, если ожидаемая польза для матери превосходит потенциальный риск для плода. В случае назначения препарата во время беременности - следует применять минимальное количество мази на протяжении минимального периода времени.\u003Cbr /\u003EПериод грудного вскармливания\u003Cbr /\u003EПрименение препарата в период грудного вскармливания противопоказано.\u003Cbr /\u003E"},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Исследования по изучению влияния клобетазола на способность к управлению транспортными средствами или работе с механизмами не проводились. Исходя из профиля побочных реакций клобетазола для наружного применения, какоелибо неблагоприятное влияние на такие виды деятельности не ожидается."},{"name":"Особые указания","value":"С осторожностью: повышенная местная чувствительность к глюкокортикостероидам или к любому вспомогательному веществу, входящему в состав препарата; псориаз; детский возраст от года до 18 лет.\u003Cbr /\u003EМестные реакции повышенной чувствительности (см. раздел «Побочное действие») могут иметь сходство с симптомами протекающего заболевания.\u003Cbr /\u003EУ некоторых пациентов в результате повышенной системной абсорбции глюкокортикостероидов для наружного применения могут возникать проявления гиперкортицизма (синдрома Иценко-Кушинга) и обратимое угнетение гипоталамо-гипофизарно-надпочечниковой системы, ведущее к развитию глюкокортикостероидной недостаточности. Если наблюдается любое из вышеуказанных нарушений, следует отменить препарат, постепенно уменьшая частоту его нанесения, или заменить менее активным глюкокортикостероидом. Резкое прекращение лечения может привести к развитию глюкокортикостероидной недостаточности.\u003Cbr /\u003EВо время терапии препаратом необходим периодический контроль функции коры надпочечников, с помощью определения уровня кортизола в крови и моче после стимуляции надпочечников адренокортикотропным гормоном (АКТГ).\u003Cbr /\u003EК факторам риска усиления системных эффектов относятся: активность глюкокортикостероида и состав лекарственного препарата для наружного применения, продолжительность применения, нанесение препарата на обширные участки кожи, применение в закрытых областях кожи (например, на участках с опрелостью или под окклюзионной повязкой (пеленки и подгузники у младенцев могут играть роль окклюзионной повязки)), повышенное увлажнение рогового слоя кожи, использование на областях с тонкой кожей, таких, как лицо; нанесение на поврежденную кожу или при других состояниях, которые могут сопровождаться нарушением целостности кожного барьера.\u003Cbr /\u003EПрименение у детей\u003Cbr /\u003EСледует применять с осторожностью мазь Кловейт, особенно в качестве длительной терапии, у детей старше одного года, поскольку у данной группы пациентов из-за более высокого соотношения площади поверхности тела к массе тела, чем у взрослых, может всасываться пропорционально большее количество глюкортикостероидов, быстрее развиться нарушение функции гипоталамогипофизарно-надпочечниковой системы и возникнуть системные нежелательные эффекты, характерные для глюкортикостероидов, в том числе задержка роста и развития.\u003Cbr /\u003EПо возможности следует избегать лечения глюкокортикостероидами для наружного применения в течение продолжительного времени у детей младше 12 лет, так как длительное наружное применение глюкокортикостероидов может вызвать угнетение функции надпочечников.\u003Cbr /\u003EУ детей чаще, чем у взрослых, возникают атрофические изменения кожи при наружном применении глюкокортикостероидов. При назначении терапии клобетазола детям - курс лечения должен ограничиваться пятью днями, также требуется наблюдение у врача не реже одного раза в неделю. Не применять окклюзионные повязки.\u003Cbr /\u003EПрименение при псориазе\u003Cbr /\u003EС особой осторожностью следует применять препарат Кловейт у пациентов с псориазом, вследствие возможного рецидива заболевания, вызванного развитием толерантности, риска возникновения генерализованного пустулезного псориаза и развитие местных или системных токсических реакций вследствие нарушения барьерной функции кожи.\u003Cbr /\u003EПациенты с псориазом должны находится под наблюдением врача при терапии мазью Кловейт.\u003Cbr /\u003EСопутствующая инфекция\u003Cbr /\u003EВ случае развития вторичной бактериальной или грибковой инфекции необходимо назначить наружное применение антибактериального или противогрибкового препарата. Если симптомы инфекции распространяются, следует прекратить применение лекарственного препарата Кловейт до излечения инфекции.\u003Cbr /\u003EРиск развития инфекции при окклюзии\u003Cbr /\u003EТеплые, влажные условия в складках кожи, а также условия, создаваемые при наложении окклюзионной повязки, способствуют развитию бактериальной инфекции. При использовании окклюзионной повязки следует очищать кожу перед наложением новой повязки.\u003Cbr /\u003EХронические язвы голеней\u003Cbr /\u003EГлюкокортикостероиды для наружного применения в ряде случаев применяются для лечения дерматита вокруг хронических язв голеней. Однако такое применение может сопровождаться повышенной частотой возникновения местных реакций гиперчувствительности и повышенным риском развития местных инфекций.\u003Cbr /\u003EПрименение на коже лица и веках\u003Cbr /\u003EПоскольку кожа лица более подвержена развитию атрофических изменений применение препарата Кловейт — нежелательно. При назначении — терапия не более 5-ти дней.\u003Cbr /\u003EС осторожностью препарат Кловейт наносят на кожу вокруг глаз или веки с связи с риском развития глаукомы или катаракты, а также у пациентов с этими заболеваниями в анамнезе, у которых может наступить обострение течения этих заболеваний.\u003Cbr /\u003EСледует избегать попадания мази Кловейт в глаза и на слизистые оболочки. При случайном попадании препарата в глаза необходимо обильно промыть их водой.\u003Cbr /\u003EРиск развития центральной серозной хориоретинопатии\u003Cbr /\u003EЕсли у пациента возникают такие симптомы, как нечёткость зрения, либо другие зрительные нарушения, следует рассмотреть возможность направления пациента к офтальмологу для выяснения возможных причин нарушений, к которым может относиться катаракта, глаукома или редкие заболевания, такие как центральная серозная хориоретинопатия.\u003Cbr /\u003EПрименение у пожилых пациентов\u003Cbr /\u003EСледует с осторожностью применять препарат при уже имеющихся атрофических изменениях подкожной клетчатки, особенно у лиц пожилого возраста.\u003Cbr /\u003E"},{"name":"Взаимодействие","value":"Показано, что одновременное применение препаратов, способных ингибировать изофермент СYРЗА4 (например, ритонавир и итраконазол), угнетает метаболизм глюкокортикостероидов, приводя к повышению их системной экспозиции. Степень клинической значимости данного взаимодействия зависит от дозы и способа применения глюкокортикостероидов и активности ингибитора изофермента СYРЗА4."},{"name":"Регистрационный номер","value":"ЛCP-000767/10"},{"name":"Дата государственной регистрации","value":"12.03.2021"},{"name":"Владелец регистрационного удостоверения","value":"Bausch Health"},{"name":"Изготовитель","value":"Jelfa"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Польша"},{"name":"Название препарата","value":"Кловейт"},{"name":"Срок годности","value":"24 мес."}]}],"transitionId":"tr_3573239585684149617"}}}}
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Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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  • Фитол-8 Псоризан-Fito крем д/тела, 90 мл, 75 г, 1 шт., 1 уп.
    –33 %
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    Фитол-8 Псоризан-Fito крем д/тела, 90 мл, 75 г, 1 шт., 1 уп.

    Рейтинг товара: 4.4 из 5
    на основе 7 оценок
    Цена 459 ₽ вместо 689
    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Псоризан-Fito крем д/тела, 90 мл, 75 г, 1 шт., 1 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  • Псоридонт крем противопсориазный, 50 мл, 50 г, 1 шт.
    –44 %
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    Псоридонт крем противопсориазный, 50 мл, 50 г, 1 шт.

    Рейтинг товара: 4.4 из 5
    на основе 26 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 307 ₽ вместо 310
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крем противопсориазный, 50 мл, 50 г, 1 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  • Гистан крем, 30 мл, 66 г, 1 шт., 1 уп.
    –46 %
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    Гистан крем, 30 мл, 66 г, 1 шт., 1 уп.

    Рейтинг товара: 4.6 из 5
    на основе 28 оценок
    Цена 259 ₽ вместо 484
    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  • Лостерин крем, 75 мл, 102 г, 1 шт., 1 уп.
    –1 %
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    Лостерин крем, 75 мл, 102 г, 1 шт., 1 уп.

    Рейтинг товара: 5 из 5
    на основе 10 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 1 035 ₽ вместо 1 045
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  • Карталин крем д/нар. прим., 100 мл, 100 г, 1 шт., 1 уп.
    –1 %
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    Карталин крем д/нар. прим., 100 мл, 100 г, 1 шт., 1 уп.

    Рейтинг товара: 4.8 из 5
    на основе 52 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 1 160 ₽ вместо 1 172
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  • Псорикон крем д/тела, 100 г
    –31 %
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    Псорикон крем д/тела, 100 г

    Рейтинг товара: 4.4 из 5
    на основе 45 оценок
    Цена 485 ₽ вместо 699
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  • Эплан крем, 60 мл, 30 г, 1 шт., 2 уп.
    –19 %
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    Эплан крем, 60 мл, 30 г, 1 шт., 2 уп.

    Рейтинг товара: 4.9 из 5
    на основе 12 оценок
    Цена 991 ₽ вместо 1 229
    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  • Псорилом крем д/тела, 75 мл
    –39 %
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    Псорилом крем д/тела, 75 мл

    Рейтинг товара: 4.7 из 5
    на основе 37 оценок
    Цена 537 ₽ вместо 875
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  • Септисол Кожный Доктор гель косметический, 50 мл
    –42 %
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    Септисол Кожный Доктор гель косметический, 50 мл

    Рейтинг товара: 5 из 5
    на основе 2 оценки
    Цена 210 ₽ вместо 360
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  • Акрустал классический крем, 65 мл, 1 уп.
    –28 %
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    Акрустал классический крем, 65 мл, 1 уп.

    Рейтинг товара: 4.9 из 5
    на основе 29 оценок
    Цена 720 ₽ вместо 1 000
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  • Эмалан гидрогель коллагеновый, 25 мл, 1 шт., 1 уп.
    ВАМ–45 %
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    Эмалан гидрогель коллагеновый, 25 мл, 1 шт., 1 уп.

    Рейтинг товара: 4.8 из 5
    на основе 35 оценок
    Цена 358 ₽ вместо 649
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Инструкция

Показания к применению

Клобетазол является очень сильным глюкокортикостероидом, показан для краткосрочного лечения симптомов воспаления и кожного зуда при дерматозах, чувствительных к терапии глюкокортикостероидами, и при невосприимчивости к менее сильным глюкокортикостероидам (для взрослых, лиц пожилого возраста и детей старше года):
- псориаз (за исключением широко распространенного бляшечного псориаза); дерматозы, трудно поддающиеся лечению;
- красный плоский лишай;
- дискоидная красная волчанка;
- другие заболевания кожи, устойчивые к терапии менее сильными глюкокортикостероидами.

Противопоказания

- повышенная чувствительность к клобетазолу (или любым другим глюкокортикостероидам) или любому другому компоненту, входящему в состав препарата:
- нелеченые инфекции кожи;
- розовые угри (розацеа);
- акне;
- периоральный дерматит;
- кожный зуд в отсутствие воспаления;
- перианальный и генитальный зуд;
- детский возраст до 1 года;
- период грудного вскармливания.

Способ применения и дозы

Наружно.
Мазь рекомендуется применять при поражениях кожи, сопровождающихся ее сухостью, гиперкератозом и утолщением.
Взрослым, лицам пожичого возраста и детям старше года
Препарат следует наносить тонким слоем и осторожно втирать, применяя в минимальных количествах, достаточных для покрытия всего пораженного участка 1 или 2 раза в сутки до улучшения состояния, затем следует снизить частоту нанесения или заменить препарат на менее сильный. После каждого применения препарат необходимо оставить на достаточное время для впитывания перед нанесением смягчающего средства.
Для предупреждения обострений кожных заболеваний проводят короткие (прерывистые) курсы лечения препаратом Кловейт.
При более стойких поражениях, особенно при наличии гиперкератоза, действие мази для наружного применения Кловейт при необходимости может быть усилено путем наложения окклюзионной повязки из полиэтиленовой пленки на место лечения. Обычно для получения удовлетворительного ответа достаточным является наложение окклюзионной повязки на ночь. В дальнейшем улучшение обычно удается поддерживать с помощью нанесения препарата без повязки. Если в течение 2—4 недель состояние ухудшается или не улучшается, следует провести повторную оценку диагноза и лечения.
Лечение не должно продолжаться более 4 недель. Если необходимо продолжение лечения, следует применять менее сильный препарат. Максимальная доза не должна превышать 50 г мази в неделю.
Лечение препаратом Кловейт следует постепенно отменять после достижения контроля над заболеванием, а лечение смягчающим средством должно быть продолжено в качестве поддерживающей терапии.
Резкая отмена препарата Кловейт может приводить к рецидиву ранее имевшихся дерматозов.
Дерматозы, трудно поддающиеся лечению: пациенты с частыми рецидивами заболевания
В случае острого заболевания, как только будет достигнут эффект от непрерывного курса лечения препаратом Кловейт, может быть рассмотрена возможность прерывистого режима применения препарата (один раз в сутки, два раза в неделю, без окклюзионной повязки). Показано, что такое лечение эффективно снижает частоту развития рецидивов.
Нанесение препарата должно быть продолжено на все ранее пораженные участки кожи или на известные области потенциального обострения. Такая схема применения должна сочетаться с рутинным ежедневным применением смягчающих средств. Следует проводить регулярную оценку состояния пациента, а также пользы и риска от продолжения лечения.
Особые группы пациентов
Дети
Препарат Кловейт, мазь для наружного применения противопоказан у детей в возрасте до 1 года.
У детей более вероятно развитие местных и системных побочных эффектов при терапии глюкокортикостероидами для наружного применения и, как правило, им требуется проведение более коротких курсов лечения с использованием менее активных средств, чем у взрослых.
Следует соблюдать осторожность при использовании препарата Кловейт у детей, чтобы обеспечить нанесение препарата в минимальном количестве, обеспечивающем терапевтический эффект.
Курс лечения у детей должен ограничиваться, по возможности, пятью днями; требуется наблюдение у врача не реже одного раза в неделю. Окклюзионные повязки не должны применяться.
Пациенты пожилого возраста
Клинические исследования не выявили каких-либо различий в эффективности препарата у пожилых и более молодых пациентов. Большая распространенность сниженной функции печени или почек у пациентов пожилого возраста может приводить к замедлению выведения препарата в случае его системной абсорбции. Следовательно, препарат должен применяться в минимальном количестве и в течение как можно более короткого периода, до достижения необходимого клинического эффекта.
Пациенты с нарушением функции почек и/или печени
В случае системной абсорбции препарата (при нанесении на обширные поверхности кожи в течение продолжительного периода) его метаболизм и выведение могут замедляться, приводя к повышенному риску развития системных побочных эффектов. Следовательно, препарат должен применяться в минимальном количестве и в течение как можно более короткого периода, до достижения необходимого клинического эффекта.
Применение в области лица
Применение в области лица нежелательно, так как эта область более восприимчива к атрофическим изменениям.
Курс лечения должен ограничиваться, если это возможно, пятью днями. Окклюзионные повязки не должны применяться.
Полная инструкция
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Кловейт мазь
Кловейт мазь, 0,05%, 25 мл, 25 г
4.5
(34)
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2 вопроса
Инструкция

518 ₽

Скидка: 21%
–21 %
Вместо:656 ₽
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4.5
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У продавца:34 оценки·5 отзывов
У всех продавцов:122 оценки·25 отзывов
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user avatar
5 месяцев назад • Имя скрыто • Куплен на Маркете
Достоинства: Помогает, дешевле аналогов.
Недостатки: Это мазь, а в виде крема была бы удобнее в применении.
Комментарий: Хорошее средство на свою цену.
user avatar
11 месяцев назад • ИжМалЭтаж С. • Куплен на Маркете
Достоинства: при ипользовании сразу все шелушения стали проходить, хотя до этого долго использовал мазь фенивейт.
user avatar
10 месяцев назад • АНТОН СМЫСЛОВ • Куплен на Маркете
Достоинства: Помогает
Комментарий: Ещё раз приобрету
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    Цена 396 ₽ вместо 510
  • Пластырь-повязка 20*10 см, медицинская стерильная на рану и шов, 10 штук Fixplast с сорбционной подушечкой
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    Пластырь-повязка 20*10 см, медицинская стерильная на рану и шов, 10 штук Fixplast с сорбционной подушечкой

    Цена 234 ₽ вместо 379
  • БиоГая Пробиотик капли детск. фл., 5 мл, 1 уп.
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    БиоГая Пробиотик капли детск. фл., 5 мл, 1 уп.

    Цена 1 752 ₽ вместо 3 500
  • Лостерин крем, 75 мл, 102 г, 1 шт., 1 уп.
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    Лостерин крем, 75 мл, 102 г, 1 шт., 1 уп.

    Цена 1 035 ₽ вместо 1 045
  • Салфетка спиртовая (этиловый спирт) 60*100 мм 300 шт.
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    Салфетка спиртовая (этиловый спирт) 60*100 мм 300 шт.

    Цена 406 ₽ вместо 756
  • Силденафил-СЗ таб. п/о плен., 100 мг, 10 шт.
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    Силденафил-СЗ таб. п/о плен., 100 мг, 10 шт.

    Цена 314 ₽
  • Тадалафил-СЗ таб. п/о плен., 20 мг, 8 шт.
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    Тадалафил-СЗ таб. п/о плен., 20 мг, 8 шт.

    Цена 341 ₽
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    Реклама
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  • Жидкий пластырь Fixplast c пантенолом, 60 мл
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    Жидкий пластырь Fixplast c пантенолом, 60 мл

    Цена 355 ₽ вместо 399
  • Фенибут таб., 250 мг, 20 шт.
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    Фенибут таб., 250 мг, 20 шт.

    Цена 112 ₽
  • Фитол-8 Псоризан-Fito крем д/тела, 90 мл, 75 г, 1 шт., 1 уп.
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    Фитол-8 Псоризан-Fito крем д/тела, 90 мл, 75 г, 1 шт., 1 уп.

    Цена 459 ₽ вместо 689
  • ЛимфоТранзит концентрат напитка фл., 100 мл
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1780857920_12/content/content/gallery":{"title":"ЛимфоТранзит концентрат напитка фл., 100 мл","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/4489193/img_id4629792869941954388.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4489193/img_id4629792869941954388.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4489193/img_id4629792869941954388.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4489193/img_id4629792869941954388.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4489193/img_id4629792869941954388.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4489193/img_id4629792869941954388.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4880383/img_id7613492906357521498.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4880383/img_id7613492906357521498.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4880383/img_id7613492906357521498.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4880383/img_id7613492906357521498.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4880383/img_id7613492906357521498.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4880383/img_id7613492906357521498.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4012265/img_id719118711323658415.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4012265/img_id719118711323658415.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4012265/img_id719118711323658415.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4012265/img_id719118711323658415.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4012265/img_id719118711323658415.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4012265/img_id719118711323658415.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4322107/img_id1313108835997666733.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4322107/img_id1313108835997666733.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4322107/img_id1313108835997666733.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4322107/img_id1313108835997666733.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4322107/img_id1313108835997666733.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4322107/img_id1313108835997666733.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQveennOav1e5DEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCMD4ltEGEI2Jl7wCGNW7oQYg19zBBw==","sign":"l3XBPh/Yh7n62jzT22GiEkXXDA4xUsrFPvCUFKreGrk="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1780857920_12/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
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    ЛимфоТранзит концентрат напитка фл., 100 мл

    Цена 361 ₽ вместо 365
  • "Асептика" - Салфетки спиртовые антисептические, 6х10см, 100шт
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    "Асептика" - Салфетки спиртовые антисептические, 6х10см, 100шт

    Цена 210 ₽ вместо 250
  • Псоридонт крем противопсориазный, 50 мл, 50 г, 1 шт.
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    Псоридонт крем противопсориазный, 50 мл, 50 г, 1 шт.

    Цена 307 ₽ вместо 550
  • Карталин крем д/нар. прим., 100 мл, 100 г, 1 шт., 1 уп.
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    Карталин крем д/нар. прим., 100 мл, 100 г, 1 шт., 1 уп.

    Цена 1 160 ₽ вместо 1 172
  • Псорилом крем д/тела, 75 мл
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    Псорилом крем д/тела, 75 мл

    Цена 537 ₽ вместо 875
  • Эплан крем, 20 мл, 30 г, 1 шт., 1 уп.
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    Эплан крем, 20 мл, 30 г, 1 шт., 1 уп.

    Цена 400 ₽ вместо 537
  • Септисол Кожный Доктор гель косметический, 50 мл
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    Септисол Кожный Доктор гель косметический, 50 мл

    Цена 210 ₽ вместо 360
  • Акрустал классический крем, 65 мл, 1 уп.
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    Акрустал классический крем, 65 мл, 1 уп.

    Цена 720 ₽ вместо 1 000
  • Тербинафин крем, 1%, 15 г, 1 шт.
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    Тербинафин крем, 1%, 15 г, 1 шт.

    Цена 79 ₽ вместо 80
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    Реклама
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  • Гистан крем, 30 мл, 66 г, 1 шт., 1 уп.
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    Гистан крем, 30 мл, 66 г, 1 шт., 1 уп.

    Цена 259 ₽ вместо 484
  • Эмалан гидрогель коллагеновый, 25 мл, 1 шт., 1 уп.
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    Эмалан гидрогель коллагеновый, 25 мл, 1 шт., 1 уп.

    Цена 358 ₽ вместо 649
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