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Описание

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Латанопрост-Оптик гл. капли фл., 0.005%, 5 мл

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5.0
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Объем, мл: 5

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Коротко о товаре

Артикул Маркета
3123241234
Тип препарата
Действующее вещество
Возраст
от 1 года
Форма выпуска
капли
Инструкция
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Оптимальный эффект достигается при применении препарата вечером.\u003Cbr\u003EНе следует осуществлять инстилляцию препарата чаще, чем 1 раз в день, поскольку показано, что более частое введение снижает гипотензивный эффект.\u003Cbr\u003EПри пропуске одной дозы лечение продолжают по обычной схеме. Как при применении любых глазных капель, с целью снижения возможного системного эффекта препарата, сразу после инстилляции каждой капли рекомендуется в течение 1 минуты надавливать на нижнюю слезную точку, расположенную у внутреннего угла глаза на нижнем веке. Эту процедуру необходимо выполнять непосредственно после инстилляции.\u003Cbr\u003EПеред инстилляцией необходимо снять контактные линзы и установить их не раньше, чем через 15 минут после введения. Если одновременно необходимо применять другие глазные капли, их применение следует разграничить 5-минутным интервалом.\u003Cbr\u003EРежим дозирования у детей\u003Cbr\u003EЛатанопрост применяют у детей в той же дозе, что и у взрослых. Данные о применении препарата у недоношенных (гестационный возраст \u003C36 недель) отсутствуют.\u003Cbr\u003EДанные у детей \u003C 1 года сильно ограничены."},{"name":"Побочные действия","value":"Большинство нежелательных реакций отмечались со стороны органа зрения. В открытом 5- летнем исследовании безопасности у 33 % развилась пигментация радужной оболочки. Прочие нежелательные реакции со стороны органа зрения, как правило, транзиторны и отмечаются непосредственно после инстилляции.\u003Cbr\u003EГрадация нежелательных реакций по частоте встречаемости осуществлялась следующим образом: очень часто (≥1/10); часто (≥1/100, \u003C1/10); нечасто (≥1/1000, \u003C1/100); редко (≥1/10 000, \u003C1/1000); очень редко (\u003C1/10 000); частота неизвестна (на основе имеющихся данных частоту оценить невозможно).\u003Cbr\u003EИнфекции и инвазии\u003Cbr\u003EЧастота неизвестна: герпетический кератит.\u003Cbr\u003EСо стороны органа зрения\u003Cbr\u003EОчень часто: гиперпигментация радужной оболочки, гиперемия конъюнктивы, раздражение глаз от легкой до средней степени (чувство жжения, ощущение песка в глазах, зуд, покалывание и ощущение инородного тела), изменение ресниц (увеличение длины, толщины, количества и пигментации).\u003Cbr\u003EЧасто: преходящие точечные эрозии эпителия (преимущественно бессимптомные), блефарит, боль в глазу.\u003Cbr\u003EНечасто: отек век, сухость слизистой оболочки глаза, кератит, затуманивание зрения, конъюнктивит.\u003Cbr\u003EРедко: ирит/увеит (преимущественно у предрасположенных пациентов), отек макулы, отек век, отек роговицы, эрозия роговицы, периорбитальный отек, потемнение кожи век, реакции со стороны кожи век, изменение направления роста ресниц, утолщение, потемнение и удлинение ресниц, дистихиаз, фотофобия.\u003Cbr\u003EОчень редко: изменения в периорбитальной области и в области ресниц, приводящие к углублению борозды верхнего века.\u003Cbr\u003EЧастота неизвестна: киста радужной оболочки, псевдопемфигоид конъюнктивы.\u003Cbr\u003EСо стороны нервной системы\u003Cbr\u003EЧастота неизвестна: головокружение, головная боль.\u003Cbr\u003EСо стороны сердца\u003Cbr\u003EНечасто: стенокардия, ощущение сердцебиения.\u003Cbr\u003EЧастота неизвестна: нестабильная стенокардия.\u003Cbr\u003EСо стороны органов дыхания\u003Cbr\u003EРедко: бронхоспазм (в т.ч. обострение заболевания у пациентов с бронхиальной астмой в анамнезе), одышка.\u003Cbr\u003EСо стороны кожи и подкожных тканей\u003Cbr\u003EНечасто: сыпь.\u003Cbr\u003EРедко: кожный зуд.\u003Cbr\u003EОчень редко: потемнение кожи век и местные кожные реакции на веках.\u003Cbr\u003EСо стороны опорно-двигательного аппарата и соединительной ткани\u003Cbr\u003EЧастота неизвестна: миалгия, артралгия.\u003Cbr\u003EОбщие нарушения и местные реакции\u003Cbr\u003EОчень редко: боль в груди."},{"name":"Фармакологическое действие","value":"Латанопрост - аналог простагландина F2α - является селективным агонистом рецепторов FP (простагландина F) и снижает внутриглазное давление (ВГД) за счет увеличения оттока водянистой влаги, главным образом увеосклеральным путем, а также через трабекулярную сеть. Снижение ВГД начинается приблизительно через 3-4 ч после введения препарата, максимальный эффект наблюдается через 8-12 ч, действие сохраняется в течение не менее 24 ч.\u003Cbr\u003EУстановлено, что латанопрост не оказывает существенного влияния на продукцию водянистой влаги и на гематоофтальмический барьер.\u003Cbr\u003EПри применении в терапевтических дозах латанопрост не оказывает значимого фармакологического эффекта на сердечно-сосудистую и дыхательную системы."},{"name":"Фармакологическая группа","value":"противоглаукомное средство (простагландина F2-альфа аналог синтетический)"},{"name":"Форма выпуска","value":"капли"},{"name":"Способ применения/введения","value":"конъюктивальный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-glaz-i-ushei","categoryId":"15756892","navnodeId":"72496","glfilters":["35947170:36763746"]}}},{"name":"Минимальный возраст применения","value":"от 1 года"},{"name":"Условия хранения","value":"В оригинальной упаковке при температуре от 2 до 8 °С.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"Помимо раздражения слизистой оболочки глаз, гиперемии конъюнктивы или эписклеры, другие нежелательные изменения со стороны органа зрения при передозировке латанопроста не известны.\u003Cbr\u003EПри случайном приеме латанопроста внутрь следует учитывать следующую информацию: один флакон с 2,5 мл раствора содержит 125 мкг латанопроста. Более 90% препарата метаболизируется при первом прохождении через печень. Внутривенная инфузия в дозе 3 мкг/кг у здоровых добровольцев не вызывала каких-либо симптомов, однако при введении дозы 5,5-10 мкг/кг наблюдались тошнота, боль в животе, головокружение, утомляемость, приливы и потливость. У больных бронхиальной астмой средней степени тяжести введение латанопроста в глаза в дозе, в 7 раз превышающей терапевтическую, не вызывало бронхоспазма.\u003Cbr\u003EВ случае передозировки проводят симптоматическое лечение."},{"name":"Применение при беременности и кормлении грудью","value":"Беременность\u003Cbr\u003EБезопасность применения латанопроста во время беременности у человека не установлена. Латанопрост может оказывать токсические эффекты на течение беременности, плод и новорожденного. Применение во время беременности противопоказано.\u003Cbr\u003EПериод грудного вскармливания\u003Cbr\u003EЛатанопрост и его метаболиты могут проникать в грудное молоко. Применение во время грудного вскармливания противопоказано. При необходимости приема препарата грудное вскармливание необходимо прекратить.\u003Cbr\u003EФертильность\u003Cbr\u003EВлияния латанопроста на мужскую и женскую фертильность в исследованиях на животных не обнаружено."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Как и при применении других офтальмологических лекарственных препаратов, возможно временное нарушение зрения; до его восстановления управлять транспортными средствами или работать с механизмами не рекомендуется."},{"name":"Особые указания","value":"Латанопрост может постепенно изменить цвет глаз за счет увеличения содержания коричневого пигмента в радужке. До начала лечения пациентов следует проинформировать о возможном необратимом изменении цвета глаз. Применение лекарственного препарата на одном глазу может вызвать необратимую гетерохромию. Такое изменение цвета глаз преимущественно отмечалось у пациентов с неравномерно окрашенными радужками, а именно: каре-голубыми, серо-карими, желто-карими и зелено-карими. В исследованиях латанопроста потемнение, как правило, начиналось в течение первых 8 месяцев лечения, редко - в течение второго и третьего года и не отмечалось по истечении четырех лет лечения. Прогрессирование пигментации радужки снижалось со временем и стабилизировалось через 5 лет. Данные об усилении пигментации в течение 5 лет отсутствуют. В открытом 5-летнем исследовании безопасности латанопроста у 33% пациентов развивалась пигментация радужки. В большинстве случаев изменение цвета радужки было незначительным и, зачастую, клинически не выявлялось. Частота встречаемости колебалась от 7 до 85% у пациентов с неодинакового цвета радужками, преобладая у пациентов с желто-карими радужками. Изменения у пациентов с равномерно окрашенными радужками голубого цвета не наблюдались, в редких случаях изменения отмечались при равномерно окрашенных радужках серого, зеленого и карего цветов.\u003Cbr\u003EИзменение цвета глаз обусловлено увеличением содержания меланина в стромальных меланоцитах радужки, а не увеличением числа самих меланоцитов. В типичных случаях коричневая пигментация появляется вокруг зрачка и концентрически распространяется на периферию радужки. При этом вся радужка или ее части приобретают карий цвет. После отмены терапии дальнейшая пигментация не отмечалась. По имеющимся клиническим данным изменение цвета не было связано с какими-либо симптомами или патологическими нарушениями.\u003Cbr\u003EПрепарат не оказывает влияния на невусы и лентиго радужной оболочки. Согласно результатам 5-летних клинических исследований, накопления пигмента в склеророговичной трабекулярной сети или иных отделах передней камеры глаза не отмечено. Показано, что потемнение радужки не приводит к нежелательным клиническим последствиям, поэтому применение латанопроста при возникновении такого потемнения можно продолжить. Тем не менее такие пациенты должны находиться под регулярным наблюдением и, в зависимости от клинической ситуации, лечение может быть прекращено.\u003Cbr\u003EОпыт применения латанопроста в терапии закрытоугольной и врожденной глаукомы, пигментной глаукомы, открытоугольной глаукомы у пациентов с псевдоафакией ограничен. Отсутствуют сведения о применении латанопроста в лечении вторичной глаукомы вследствие воспалительных заболеваний глаз и неоваскулярной глаукомы.\u003Cbr\u003EЛатанопрост не оказывает влияния на величину зрачка.\u003Cbr\u003EВ связи с тем, что сведения о применении латанопроста в послеоперационном периоде экстракции катаракты ограничены, следует соблюдать осторожность при применении препарата у этой категории пациентов.\u003Cbr\u003EСледует соблюдать осторожность при применении латанопроста пациентами с герпетическим кератитом в анамнезе. При остром герпетическом кератите, а также в случае наличия анамнестических сведений о хроническом рецидивирующем герпетическом кератите, необходимо избегать назначения латанопроста.\u003Cbr\u003EМакулярный отек, в том числе кистозный, отмечался в период терапии латанопростом преимущественно у пациентов с афакисй, пссвдоафакией, разрывом задней капсулы хрусталика, или у пациентов с факторами риска развития кистозного макулярного отека (в частности, при диабетической ретинопатии и окклюзии вен сетчатки).\u003Cbr\u003EСледует соблюдать осторожность при применении латанопроста пациентами с афакией, псевдоафакией с разрывом задней капсулы или переднекамерными интраокулярными линзами, а также пациентами с известными факторами риска кистозного отека макулы.\u003Cbr\u003EСледует соблюдать осторожность при применении латанопроста пациентами с факторами риска развития ирита/увеита.\u003Cbr\u003EОпыт применения латанопроста пациентами с бронхиальной астмой ограничен, но в ряде случаев в пострегистрационном периоде отмечались обострение течения астмы и/или появления одышки. Следует соблюдать осторожность при применении латанопроста у этой категории пациентов.\u003Cbr\u003EОтмечались случаи потемнения кожи периорбитальной области, которые у ряда пациентов носили обратимый характер при продолжении терапии латанопростом.\u003Cbr\u003EЛатанопрост может вызывать постепенные изменения ресниц и пушковых волос, такие как удлинение, утолщение, усиление пигментации, увеличение густоты и изменение направления роста ресниц. Изменения ресниц были обратимы и проходили после прекращения терапии.\u003Cbr\u003EЛатанопрост-Оптик содержит бензалкония хлорид, часто используемый в качестве консерванта в офтальмологических лекарственных препаратах. Бензалкония хлорид может вызывать раздражения глаз, точечную кератопатию и/или токсическую язвенную кератопатию, а также абсорбироваться мягкими контактными линзами и обесцвечивать их. Требуется тщательный мониторинг состояния пациентов с синдромом \"сухого\" глаза или других заболеваний роговицы при длительном применении латанопроста. Перед применением препарата необходимо снять контактные линзы и снова установить их не ранее чем через 15 минут после инстилляции.\u003Cbr\u003EДети\u003Cbr\u003EСведения об эффективности и безопасности применения латанопроста у детей младше года ограничены. Отсутствует опыт применения препарата у недоношенных детей (гестационный возраст менее 36 недель).\u003Cbr\u003EСведения о безопасности долгосрочного применения латанопроста у детей отсутствуют. При первичной врожденной глаукоме у детей от 0 до 3 лет стандартным методом лечения остается хирургическое вмешательство (гониотомия/трабекулотомия)."},{"name":"Взаимодействие","value":"При одновременном закапывании в глаза двух аналогов простагландинов описано парадоксальное повышение ВГД, поэтому одновременное применение двух и более простагландинов, их аналогов или производных не рекомендуется.\u003Cbr\u003EФармацевтически несовместим с глазными каплями, содержащими тиомерсал - преципитация."},{"name":"Регистрационный номер","value":"ЛП-005521"},{"name":"Дата государственной регистрации","value":"29.07.2020"},{"name":"Владелец регистрационного удостоверения","value":"ЛЕККО","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-glaz-i-ushei","categoryId":"15756892","navnodeId":"72496","glfilters":["34324371:35649313","7893318:16001540"]}}},{"name":"Изготовитель","value":"ЛЕККО"},{"name":"Фасовщик","value":"ЛЕККО"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Дополнительная информация","value":"назначение: снижение повышенного внутриглазного давления"},{"name":"Название препарата","value":"Латанопрост-Оптик","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-glaz-i-ushei","categoryId":"15756892","navnodeId":"72496","glfilters":["17796364:18084401"]}}},{"name":"Срок годности","value":"24 мес."}]}},"fullSpecsGrouped":{"5960581185676339325":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"глаза"},{"name":"Показания к применению","value":"Снижение повышенного внутриглазного давления у взрослых и детей (в возрасте старше 1 года) с открытоугольной глаукомой или повышенным офтальмотонусом."},{"name":"Противопоказания","value":"Повышенная чувствительность к латанопросту или другим компонентам препарата.\u003Cbr\u003EВозраст до 1 года (эффективность и безопасность не установлены)."},{"name":"Состав","value":"На 1 мл.\u003Cbr\u003EДействующее вещество: латанопрост - 0,05 мг\u003Cbr\u003EВспомогательные вещества: бензалкония хлорид в пересчете на безводное вещество - 0,20 мг, натрия хлорид - 4,10 мг, натрия дигидрофосфат моногидрат - 4,60 мг, натрия гидрофосфат безводный - 4,74 мг, вода очищенная - до 1,0 мл."},{"name":"Действующее вещество","value":"Латанопрост"},{"name":"Способ применения и дозы","value":"Местно.\u003Cbr\u003EРежим дозирования у взрослых (включая пожилых)\u003Cbr\u003EПо одной капле в пораженный глаз (а) один раз в день. Оптимальный эффект достигается при применении препарата вечером.\u003Cbr\u003EНе следует осуществлять инстилляцию препарата чаще, чем 1 раз в день, поскольку показано, что более частое введение снижает гипотензивный эффект.\u003Cbr\u003EПри пропуске одной дозы лечение продолжают по обычной схеме. Как при применении любых глазных капель, с целью снижения возможного системного эффекта препарата, сразу после инстилляции каждой капли рекомендуется в течение 1 минуты надавливать на нижнюю слезную точку, расположенную у внутреннего угла глаза на нижнем веке. Эту процедуру необходимо выполнять непосредственно после инстилляции.\u003Cbr\u003EПеред инстилляцией необходимо снять контактные линзы и установить их не раньше, чем через 15 минут после введения. Если одновременно необходимо применять другие глазные капли, их применение следует разграничить 5-минутным интервалом.\u003Cbr\u003EРежим дозирования у детей\u003Cbr\u003EЛатанопрост применяют у детей в той же дозе, что и у взрослых. Данные о применении препарата у недоношенных (гестационный возраст \u003C36 недель) отсутствуют.\u003Cbr\u003EДанные у детей \u003C 1 года сильно ограничены."},{"name":"Побочные действия","value":"Большинство нежелательных реакций отмечались со стороны органа зрения. В открытом 5- летнем исследовании безопасности у 33 % развилась пигментация радужной оболочки. Прочие нежелательные реакции со стороны органа зрения, как правило, транзиторны и отмечаются непосредственно после инстилляции.\u003Cbr\u003EГрадация нежелательных реакций по частоте встречаемости осуществлялась следующим образом: очень часто (≥1/10); часто (≥1/100, \u003C1/10); нечасто (≥1/1000, \u003C1/100); редко (≥1/10 000, \u003C1/1000); очень редко (\u003C1/10 000); частота неизвестна (на основе имеющихся данных частоту оценить невозможно).\u003Cbr\u003EИнфекции и инвазии\u003Cbr\u003EЧастота неизвестна: герпетический кератит.\u003Cbr\u003EСо стороны органа зрения\u003Cbr\u003EОчень часто: гиперпигментация радужной оболочки, гиперемия конъюнктивы, раздражение глаз от легкой до средней степени (чувство жжения, ощущение песка в глазах, зуд, покалывание и ощущение инородного тела), изменение ресниц (увеличение длины, толщины, количества и пигментации).\u003Cbr\u003EЧасто: преходящие точечные эрозии эпителия (преимущественно бессимптомные), блефарит, боль в глазу.\u003Cbr\u003EНечасто: отек век, сухость слизистой оболочки глаза, кератит, затуманивание зрения, конъюнктивит.\u003Cbr\u003EРедко: ирит/увеит (преимущественно у предрасположенных пациентов), отек макулы, отек век, отек роговицы, эрозия роговицы, периорбитальный отек, потемнение кожи век, реакции со стороны кожи век, изменение направления роста ресниц, утолщение, потемнение и удлинение ресниц, дистихиаз, фотофобия.\u003Cbr\u003EОчень редко: изменения в периорбитальной области и в области ресниц, приводящие к углублению борозды верхнего века.\u003Cbr\u003EЧастота неизвестна: киста радужной оболочки, псевдопемфигоид конъюнктивы.\u003Cbr\u003EСо стороны нервной системы\u003Cbr\u003EЧастота неизвестна: головокружение, головная боль.\u003Cbr\u003EСо стороны сердца\u003Cbr\u003EНечасто: стенокардия, ощущение сердцебиения.\u003Cbr\u003EЧастота неизвестна: нестабильная стенокардия.\u003Cbr\u003EСо стороны органов дыхания\u003Cbr\u003EРедко: бронхоспазм (в т.ч. обострение заболевания у пациентов с бронхиальной астмой в анамнезе), одышка.\u003Cbr\u003EСо стороны кожи и подкожных тканей\u003Cbr\u003EНечасто: сыпь.\u003Cbr\u003EРедко: кожный зуд.\u003Cbr\u003EОчень редко: потемнение кожи век и местные кожные реакции на веках.\u003Cbr\u003EСо стороны опорно-двигательного аппарата и соединительной ткани\u003Cbr\u003EЧастота неизвестна: миалгия, артралгия.\u003Cbr\u003EОбщие нарушения и местные реакции\u003Cbr\u003EОчень редко: боль в груди."},{"name":"Фармакологическое действие","value":"Латанопрост - аналог простагландина F2α - является селективным агонистом рецепторов FP (простагландина F) и снижает внутриглазное давление (ВГД) за счет увеличения оттока водянистой влаги, главным образом увеосклеральным путем, а также через трабекулярную сеть. Снижение ВГД начинается приблизительно через 3-4 ч после введения препарата, максимальный эффект наблюдается через 8-12 ч, действие сохраняется в течение не менее 24 ч.\u003Cbr\u003EУстановлено, что латанопрост не оказывает существенного влияния на продукцию водянистой влаги и на гематоофтальмический барьер.\u003Cbr\u003EПри применении в терапевтических дозах латанопрост не оказывает значимого фармакологического эффекта на сердечно-сосудистую и дыхательную системы."},{"name":"Фармакологическая группа","value":"противоглаукомное средство (простагландина F2-альфа аналог синтетический)"},{"name":"Форма выпуска","value":"капли"},{"name":"Способ применения/введения","value":"конъюктивальный"},{"name":"Минимальный возраст применения","value":"от 1 года"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"В оригинальной упаковке при температуре от 2 до 8 °С.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"Помимо раздражения слизистой оболочки глаз, гиперемии конъюнктивы или эписклеры, другие нежелательные изменения со стороны органа зрения при передозировке латанопроста не известны.\u003Cbr\u003EПри случайном приеме латанопроста внутрь следует учитывать следующую информацию: один флакон с 2,5 мл раствора содержит 125 мкг латанопроста. Более 90% препарата метаболизируется при первом прохождении через печень. Внутривенная инфузия в дозе 3 мкг/кг у здоровых добровольцев не вызывала каких-либо симптомов, однако при введении дозы 5,5-10 мкг/кг наблюдались тошнота, боль в животе, головокружение, утомляемость, приливы и потливость. У больных бронхиальной астмой средней степени тяжести введение латанопроста в глаза в дозе, в 7 раз превышающей терапевтическую, не вызывало бронхоспазма.\u003Cbr\u003EВ случае передозировки проводят симптоматическое лечение."},{"name":"Применение при беременности и кормлении грудью","value":"Беременность\u003Cbr\u003EБезопасность применения латанопроста во время беременности у человека не установлена. Латанопрост может оказывать токсические эффекты на течение беременности, плод и новорожденного. Применение во время беременности противопоказано.\u003Cbr\u003EПериод грудного вскармливания\u003Cbr\u003EЛатанопрост и его метаболиты могут проникать в грудное молоко. Применение во время грудного вскармливания противопоказано. При необходимости приема препарата грудное вскармливание необходимо прекратить.\u003Cbr\u003EФертильность\u003Cbr\u003EВлияния латанопроста на мужскую и женскую фертильность в исследованиях на животных не обнаружено."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Как и при применении других офтальмологических лекарственных препаратов, возможно временное нарушение зрения; до его восстановления управлять транспортными средствами или работать с механизмами не рекомендуется."},{"name":"Особые указания","value":"Латанопрост может постепенно изменить цвет глаз за счет увеличения содержания коричневого пигмента в радужке. До начала лечения пациентов следует проинформировать о возможном необратимом изменении цвета глаз. Применение лекарственного препарата на одном глазу может вызвать необратимую гетерохромию. Такое изменение цвета глаз преимущественно отмечалось у пациентов с неравномерно окрашенными радужками, а именно: каре-голубыми, серо-карими, желто-карими и зелено-карими. В исследованиях латанопроста потемнение, как правило, начиналось в течение первых 8 месяцев лечения, редко - в течение второго и третьего года и не отмечалось по истечении четырех лет лечения. Прогрессирование пигментации радужки снижалось со временем и стабилизировалось через 5 лет. Данные об усилении пигментации в течение 5 лет отсутствуют. В открытом 5-летнем исследовании безопасности латанопроста у 33% пациентов развивалась пигментация радужки. В большинстве случаев изменение цвета радужки было незначительным и, зачастую, клинически не выявлялось. Частота встречаемости колебалась от 7 до 85% у пациентов с неодинакового цвета радужками, преобладая у пациентов с желто-карими радужками. Изменения у пациентов с равномерно окрашенными радужками голубого цвета не наблюдались, в редких случаях изменения отмечались при равномерно окрашенных радужках серого, зеленого и карего цветов.\u003Cbr\u003EИзменение цвета глаз обусловлено увеличением содержания меланина в стромальных меланоцитах радужки, а не увеличением числа самих меланоцитов. В типичных случаях коричневая пигментация появляется вокруг зрачка и концентрически распространяется на периферию радужки. При этом вся радужка или ее части приобретают карий цвет. После отмены терапии дальнейшая пигментация не отмечалась. По имеющимся клиническим данным изменение цвета не было связано с какими-либо симптомами или патологическими нарушениями.\u003Cbr\u003EПрепарат не оказывает влияния на невусы и лентиго радужной оболочки. Согласно результатам 5-летних клинических исследований, накопления пигмента в склеророговичной трабекулярной сети или иных отделах передней камеры глаза не отмечено. Показано, что потемнение радужки не приводит к нежелательным клиническим последствиям, поэтому применение латанопроста при возникновении такого потемнения можно продолжить. Тем не менее такие пациенты должны находиться под регулярным наблюдением и, в зависимости от клинической ситуации, лечение может быть прекращено.\u003Cbr\u003EОпыт применения латанопроста в терапии закрытоугольной и врожденной глаукомы, пигментной глаукомы, открытоугольной глаукомы у пациентов с псевдоафакией ограничен. Отсутствуют сведения о применении латанопроста в лечении вторичной глаукомы вследствие воспалительных заболеваний глаз и неоваскулярной глаукомы.\u003Cbr\u003EЛатанопрост не оказывает влияния на величину зрачка.\u003Cbr\u003EВ связи с тем, что сведения о применении латанопроста в послеоперационном периоде экстракции катаракты ограничены, следует соблюдать осторожность при применении препарата у этой категории пациентов.\u003Cbr\u003EСледует соблюдать осторожность при применении латанопроста пациентами с герпетическим кератитом в анамнезе. При остром герпетическом кератите, а также в случае наличия анамнестических сведений о хроническом рецидивирующем герпетическом кератите, необходимо избегать назначения латанопроста.\u003Cbr\u003EМакулярный отек, в том числе кистозный, отмечался в период терапии латанопростом преимущественно у пациентов с афакисй, пссвдоафакией, разрывом задней капсулы хрусталика, или у пациентов с факторами риска развития кистозного макулярного отека (в частности, при диабетической ретинопатии и окклюзии вен сетчатки).\u003Cbr\u003EСледует соблюдать осторожность при применении латанопроста пациентами с афакией, псевдоафакией с разрывом задней капсулы или переднекамерными интраокулярными линзами, а также пациентами с известными факторами риска кистозного отека макулы.\u003Cbr\u003EСледует соблюдать осторожность при применении латанопроста пациентами с факторами риска развития ирита/увеита.\u003Cbr\u003EОпыт применения латанопроста пациентами с бронхиальной астмой ограничен, но в ряде случаев в пострегистрационном периоде отмечались обострение течения астмы и/или появления одышки. Следует соблюдать осторожность при применении латанопроста у этой категории пациентов.\u003Cbr\u003EОтмечались случаи потемнения кожи периорбитальной области, которые у ряда пациентов носили обратимый характер при продолжении терапии латанопростом.\u003Cbr\u003EЛатанопрост может вызывать постепенные изменения ресниц и пушковых волос, такие как удлинение, утолщение, усиление пигментации, увеличение густоты и изменение направления роста ресниц. Изменения ресниц были обратимы и проходили после прекращения терапии.\u003Cbr\u003EЛатанопрост-Оптик содержит бензалкония хлорид, часто используемый в качестве консерванта в офтальмологических лекарственных препаратах. Бензалкония хлорид может вызывать раздражения глаз, точечную кератопатию и/или токсическую язвенную кератопатию, а также абсорбироваться мягкими контактными линзами и обесцвечивать их. Требуется тщательный мониторинг состояния пациентов с синдромом \"сухого\" глаза или других заболеваний роговицы при длительном применении латанопроста. Перед применением препарата необходимо снять контактные линзы и снова установить их не ранее чем через 15 минут после инстилляции.\u003Cbr\u003EДети\u003Cbr\u003EСведения об эффективности и безопасности применения латанопроста у детей младше года ограничены. Отсутствует опыт применения препарата у недоношенных детей (гестационный возраст менее 36 недель).\u003Cbr\u003EСведения о безопасности долгосрочного применения латанопроста у детей отсутствуют. При первичной врожденной глаукоме у детей от 0 до 3 лет стандартным методом лечения остается хирургическое вмешательство (гониотомия/трабекулотомия)."},{"name":"Взаимодействие","value":"При одновременном закапывании в глаза двух аналогов простагландинов описано парадоксальное повышение ВГД, поэтому одновременное применение двух и более простагландинов, их аналогов или производных не рекомендуется.\u003Cbr\u003EФармацевтически несовместим с глазными каплями, содержащими тиомерсал - преципитация."},{"name":"Регистрационный номер","value":"ЛП-005521"},{"name":"Дата государственной регистрации","value":"29.07.2020"},{"name":"Владелец регистрационного удостоверения","value":"ЛЕККО"},{"name":"Изготовитель","value":"ЛЕККО"},{"name":"Фасовщик","value":"ЛЕККО"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Дополнительная информация","value":"назначение: снижение повышенного внутриглазного давления"},{"name":"Название препарата","value":"Латанопрост-Оптик"},{"name":"Срок годности","value":"24 мес."}]}],"transitionId":"tr_7815719151765040658"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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Инструкция

Показания к применению

Снижение повышенного внутриглазного давления у взрослых и детей (в возрасте старше 1 года) с открытоугольной глаукомой или повышенным офтальмотонусом.

Противопоказания

Повышенная чувствительность к латанопросту или другим компонентам препарата.
Возраст до 1 года (эффективность и безопасность не установлены).

Способ применения и дозы

Местно.
Режим дозирования у взрослых (включая пожилых)
По одной капле в пораженный глаз (а) один раз в день. Оптимальный эффект достигается при применении препарата вечером.
Не следует осуществлять инстилляцию препарата чаще, чем 1 раз в день, поскольку показано, что более частое введение снижает гипотензивный эффект.
При пропуске одной дозы лечение продолжают по обычной схеме. Как при применении любых глазных капель, с целью снижения возможного системного эффекта препарата, сразу после инстилляции каждой капли рекомендуется в течение 1 минуты надавливать на нижнюю слезную точку, расположенную у внутреннего угла глаза на нижнем веке. Эту процедуру необходимо выполнять непосредственно после инстилляции.
Перед инстилляцией необходимо снять контактные линзы и установить их не раньше, чем через 15 минут после введения. Если одновременно необходимо применять другие глазные капли, их применение следует разграничить 5-минутным интервалом.
Режим дозирования у детей
Латанопрост применяют у детей в той же дозе, что и у взрослых. Данные о применении препарата у недоношенных (гестационный возраст <36 недель) отсутствуют.
Данные у детей < 1 года сильно ограничены.
Полная инструкция
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Латанопрост-Оптик гл. капли фл.
Латанопрост-Оптик гл. капли фл., 0.005%, 5 мл
5.0
(4)
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2 вопроса
Инструкция

443 ₽

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    Renu Advanced раствор для линз универсальный 100 мл 1 шт

    Цена 368 ₽ вместо 372
  • Контактные линзы ACUVUE OASYS 1-Day with HydraLuxe, 90 шт., R 9, D -5
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    Контактные линзы ACUVUE OASYS 1-Day with HydraLuxe, 90 шт., R 9, D -5

    Цена 6 359 ₽ вместо 8 766
  • Спрей с салфеткой и отверткой для очков Stax в пластиковом футляре, 30мл, 19х23см
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    Спрей с салфеткой и отверткой для очков Stax в пластиковом футляре, 30мл, 19х23см

    Цена 370 ₽ вместо 680
  • Раствор Alcon AOsept Plus HydraGlyde, с контейнером, 360 мл, 1 шт.
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    Раствор Alcon AOsept Plus HydraGlyde, с контейнером, 360 мл, 1 шт.

    Цена 2 079 ₽ вместо 3 700
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