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Описание

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Лерканидипин-СЗ таб. п/о плен., 20 мг, 60 шт., 1

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5.0
(26)
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Дозировка: 20 мг

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Количество штук в упаковке, шт.: 60

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Коротко о товаре

Артикул Маркета
4319886729
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
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В зависимости от достигнутого терапевтического эффекта доза может быть увеличена до 20 мг. Терапевтическую дозу подбирают постепенно, при необходимости, увеличение дозы до 20 мг осуществляется через 2 недели после начала лечения."},{"name":"Побочные действия","value":"Со стороны сердечно-сосудистой системы: редко отмечались эффекты, связанные с сосудорасширяющим действием - периферические отеки, ощущение \"приливов\" крови к лицу, сердцебиение, тахикардия, боль в груди, снижение АД, стенокардия, инфаркт миокарда, астения, утомляемость, головная боль, головокружение. Со стороны пищеварительной системы: очень редко - диспепсия, тошнота, рвота, боль в эпигастрии, диарея, обратимое повышение активности печеночных ферментов, гиперплазия десен. Прочие: очень редко - полиурия, кожная сыпь, сонливость, миалгия."},{"name":"Фармакологическое действие","value":"Блокатор медленных кальциевых каналов, производное дигидропиридинового ряда. Ингибирует трансмембранный ток кальция в кардиомиоциты и клетки гладкой мускулатуры. Механизм гипотензивного эффекта обусловлен прямым релаксирующим действием на гладкие мышцы сосудов, в результате этого снижается ОПСС. Обладает пролонгированным антигипертензивным действием. Благодаря высокой селективности отрицательное инотропное действие отсутствует. Длительность терапевтического действия составляет 24 ч."},{"name":"Фармакологическая группа","value":"блокатор \"медленных\" кальциевых каналов"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"В защищенном от света месте, при температуре не выше 25 °С.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"Предположительно, в случае передозировки лерканидипина будут наблюдаться симптомы, сходные с таковыми при передозировке других производных дигидропиридина (периферическая вазодилатация с выраженным снижением АД и рефлекторной тахикардией), тошнота.\u003Cbr\u003EЛечение\u003Cbr\u003EСимптоматическое. В случае выраженного снижения АД, потери сознания показана сердечно-сосудистая терапия, при брадикардии - внутривенное введение атропина. Информация об эффективности гемодиализа отсутствует. Учитывая высокую степень связи с белками плазмы крови, диализ может быть неэффективным.\u003Cbr\u003EИмеются данные о трех случаях передозировки при приеме лерканидипина в дозах 150 мг, 280 мг и 800 мг. Во всех случаях передозировки пациенты остались живы.\u003Cbr\u003EВ случае одновременного приема 150 мг лерканидипина с этанолом (неустановленное количество) наблюдалась сонливость. Лечение: промывание желудка, прием внутрь активированного угля.\u003Cbr\u003EВ случае одновременного приема 280 мг лерканидипина с 5,6 мг моксонидина наблюдались следующие симптомы: кардиогенный шок, выраженная ишемия миокарда, почечная недостаточность легкой степени. Лечение: сердечные гликозиды, диуретики (фуросемид), высокие дозы катехоламинов, плазмозаменители.\u003Cbr\u003EВ случае приема 800 мг лерканидипина наблюдались: тошнота, выраженное снижение АД. Лечение: прием внутрь активированного угля и слабительных средств, внутривенно - допамин."},{"name":"Применение при беременности и кормлении грудью","value":"Противопоказано."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В период лечения следует соблюдать осторожность при выполнении работ, требующих повышенного внимания, при управлении транспортными средствами, особенно в начале лечения и при повышении дозы препарата (риск развития сонливости, головной боли и головокружения)."},{"name":"Особые указания","value":"С осторожностью применять при почечной и/или печеночной недостаточности легкой и умеренной степени, у пациентов пожилого возраста, при СССУ (без кардиостимулятора), ИБС, дисфункции левого желудочка."},{"name":"Взаимодействие","value":"При одновременном применении с ингибиторами CYPЗА4 (в т.ч. с кетоконазолом, интраконазолом, эритромицином) возможны проявления лекарственного взаимодействия (комбинации применять с осторожностью). При применении совместно с индукторами CYP3A4 (в т.ч. с антидепрессантами, рифампицином) возможно уменьшение антигипертензивного действия лерканидипина. Возможно усиление гипотензивного эффекта лерканидипина при употреблении сока грейпфрута. Этанол может потенцировать действие лерканидипина. При одновременном применении с метопрололом, биодоступность лерканидипина уменьшается на 50%. Этот эффект может встречаться и при одновременном применении с другими бета-адреноблокаторами, поэтому может потребоваться коррекция дозы лерканидипина для достижения терапевтического эффекта при данной комбинации. Лерканидипин метаболизируется при участии изофермента CYP3A4, поэтому ингибиторы и индукторы этого изофермента, при одновременном применении, могут влиять на метаболизм и выведение лерканидипина. Не рекомендуется одновременное применение лерканидипина с ингибиторами CYP3A4 (кетоконазол, итраконазол, ритонавир, эритромицин, тролеандомицин). Не рекомендуется одновременное применение циклоспорина и лерканидипина, т.к. наблюдается увеличение концентрации обоих веществ в плазме крови. Следует проявлять осторожность при одновременном применении лерканидипина с другими субстратами CYP3A4 (терфенадин, астемизол, антиаритмические препараты III класса, например, амиодарон, хинидин). При одновременном применении лерканидипина в дозе 20 мг с мидазоламом биодоступность лерканидипина у пациентов пожилого возраста может увеличиваться приблизительно на 40%. Лерканидипин следует назначать с осторожностью одновременно с индукторами CYP3A4, например, противосудорожные средства (фенитоин, карбамазепин) и рифампицин, поскольку возможно снижение антигипертензивного действия препарата. Необходим регулярный контроль АД. При одновременном применении лерканидипина в дозе 20 мг у пациентов, постоянно принимающих бета-метилдигоксин, не было отмечено фармакокинетического взаимодействия, в то время как у здоровых добровольцев, которых лечили дигоксином, отмечалось увеличение значения Cmax для дигоксина в среднем на 33% после приема 20 мг лерканидипина натощак, при этом AUC и почечный клиренс изменялись незначительно. Необходимо контролировать наличие признаков интоксикации дигоксином у пациентов, принимающих одновременно дигоксин и лерканидипин. Одновременное применение лерканидипина с циметидином (до 800 мг) не вызывает значительных изменений концентрации лерканидипина в плазме крови. При высоких дозах циметидина могут увеличиваться биодоступность и антигипертензивное действие лерканидипина. При одновременном применении лерканидипина (20 мг) и симвастатина (40 мг), значение AUC для симвастатина увеличивалось на 56%, а это же значение для его активного метаболита - β-гидроксикислоты - на 28%. При приеме препаратов в разное время суток (лерканидипин - утром, симвастатин - вечером) можно избежать нежелательного взаимодействия. Возможно усиление антигипертензивного действия при одновременном приеме сока грейпфрута и лерканидипина. Этанол может потенцировать антигипертензивное действие лерканидипина."},{"name":"Регистрационный номер","value":"ЛП-№(001095)-(РГ-RU)"},{"name":"Дата государственной регистрации","value":"02.08.2022"},{"name":"Владелец регистрационного удостоверения","value":"Северная Звезда","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["34324371:35649313","7893318:16002862"]}}},{"name":"Изготовитель","value":"Северная Звезда"},{"name":"Фасовщик","value":"Северная Звезда"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Лерканидипин-СЗ","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-serdtsa-i-sosudov","categoryId":"15756887","navnodeId":"72494","glfilters":["17796364:18020747"]}}},{"name":"Срок годности","value":"1 г."}]}},"fullSpecsGrouped":{"17403854221517018489":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"кровеносная система, кровеносные сосуды, сердце"},{"name":"Назначение","value":"артериальная гипертензия, гипертония, эссенциальная гипертензия"},{"name":"Показания к применению","value":"Мягкая и умеренная эссенциальная артериальная гипертензия."},{"name":"Противопоказания","value":"Хроническая сердечная недостаточность в стадии декомпенсации; нестабильная стенокардия; аортальный стеноз; в течение 1 месяца после перенесенного инфаркта миокарда; выраженные нарушения функции печени; нарушение функции почек (КК менее 10 мл/мин); непереносимость лактозы; галактоземия; синдром нарушенного всасывания глюкозы/галактозы; беременность; период лактации (грудного вскармливания); женщины детородного возраста, не пользующиеся надежной контрацепцией; детский и подростковый возраст до 18 лет; повышенная чувствительность к компонентам препарата; повышенная чувствительность к другим производным дигидропиридинового ряда."},{"name":"Состав","value":"Действующее вещество: лерканидипина гидрохлорид – 10 мг\u003Cbr\u003EВспомогательные вещества: лактозы моногидрат (сахар молочный) – 31.5 мг, целлюлоза микрокристаллическая – 38.5 мг, натрия гликолат крахмала – 15.5 мг, гипромеллоза (гидроксипропилметилцеллюлоза) – 3.5 мг, магния стеарат – 1 мг.\u003Cbr\u003EДействующее вещество: лерканидипина гидрохлорид – 20 мг\u003Cbr\u003EВспомогательные вещества: лактозы моногидрат (сахар молочный) – 63 мг, целлюлоза микрокристаллическая – 77 мг, натрия гликолат крахмала – 31 мг, гипромеллоза (гидроксипропилметилцеллюлоза) – 7 мг, магния стеарат – 2 мг."},{"name":"Действующее вещество","value":"Лерканидипин"},{"name":"Способ применения и дозы","value":"Внутрь по 10 мг 1 раз/сут не менее чем за 15 минут до еды, предпочтительно утром. В зависимости от достигнутого терапевтического эффекта доза может быть увеличена до 20 мг. Терапевтическую дозу подбирают постепенно, при необходимости, увеличение дозы до 20 мг осуществляется через 2 недели после начала лечения."},{"name":"Побочные действия","value":"Со стороны сердечно-сосудистой системы: редко отмечались эффекты, связанные с сосудорасширяющим действием - периферические отеки, ощущение \"приливов\" крови к лицу, сердцебиение, тахикардия, боль в груди, снижение АД, стенокардия, инфаркт миокарда, астения, утомляемость, головная боль, головокружение. Со стороны пищеварительной системы: очень редко - диспепсия, тошнота, рвота, боль в эпигастрии, диарея, обратимое повышение активности печеночных ферментов, гиперплазия десен. Прочие: очень редко - полиурия, кожная сыпь, сонливость, миалгия."},{"name":"Фармакологическое действие","value":"Блокатор медленных кальциевых каналов, производное дигидропиридинового ряда. Ингибирует трансмембранный ток кальция в кардиомиоциты и клетки гладкой мускулатуры. Механизм гипотензивного эффекта обусловлен прямым релаксирующим действием на гладкие мышцы сосудов, в результате этого снижается ОПСС. Обладает пролонгированным антигипертензивным действием. Благодаря высокой селективности отрицательное инотропное действие отсутствует. Длительность терапевтического действия составляет 24 ч."},{"name":"Фармакологическая группа","value":"блокатор \"медленных\" кальциевых каналов"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"В защищенном от света месте, при температуре не выше 25 °С.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"Предположительно, в случае передозировки лерканидипина будут наблюдаться симптомы, сходные с таковыми при передозировке других производных дигидропиридина (периферическая вазодилатация с выраженным снижением АД и рефлекторной тахикардией), тошнота.\u003Cbr\u003EЛечение\u003Cbr\u003EСимптоматическое. В случае выраженного снижения АД, потери сознания показана сердечно-сосудистая терапия, при брадикардии - внутривенное введение атропина. Информация об эффективности гемодиализа отсутствует. Учитывая высокую степень связи с белками плазмы крови, диализ может быть неэффективным.\u003Cbr\u003EИмеются данные о трех случаях передозировки при приеме лерканидипина в дозах 150 мг, 280 мг и 800 мг. Во всех случаях передозировки пациенты остались живы.\u003Cbr\u003EВ случае одновременного приема 150 мг лерканидипина с этанолом (неустановленное количество) наблюдалась сонливость. Лечение: промывание желудка, прием внутрь активированного угля.\u003Cbr\u003EВ случае одновременного приема 280 мг лерканидипина с 5,6 мг моксонидина наблюдались следующие симптомы: кардиогенный шок, выраженная ишемия миокарда, почечная недостаточность легкой степени. Лечение: сердечные гликозиды, диуретики (фуросемид), высокие дозы катехоламинов, плазмозаменители.\u003Cbr\u003EВ случае приема 800 мг лерканидипина наблюдались: тошнота, выраженное снижение АД. Лечение: прием внутрь активированного угля и слабительных средств, внутривенно - допамин."},{"name":"Применение при беременности и кормлении грудью","value":"Противопоказано."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В период лечения следует соблюдать осторожность при выполнении работ, требующих повышенного внимания, при управлении транспортными средствами, особенно в начале лечения и при повышении дозы препарата (риск развития сонливости, головной боли и головокружения)."},{"name":"Особые указания","value":"С осторожностью применять при почечной и/или печеночной недостаточности легкой и умеренной степени, у пациентов пожилого возраста, при СССУ (без кардиостимулятора), ИБС, дисфункции левого желудочка."},{"name":"Взаимодействие","value":"При одновременном применении с ингибиторами CYPЗА4 (в т.ч. с кетоконазолом, интраконазолом, эритромицином) возможны проявления лекарственного взаимодействия (комбинации применять с осторожностью). При применении совместно с индукторами CYP3A4 (в т.ч. с антидепрессантами, рифампицином) возможно уменьшение антигипертензивного действия лерканидипина. Возможно усиление гипотензивного эффекта лерканидипина при употреблении сока грейпфрута. Этанол может потенцировать действие лерканидипина. При одновременном применении с метопрололом, биодоступность лерканидипина уменьшается на 50%. Этот эффект может встречаться и при одновременном применении с другими бета-адреноблокаторами, поэтому может потребоваться коррекция дозы лерканидипина для достижения терапевтического эффекта при данной комбинации. Лерканидипин метаболизируется при участии изофермента CYP3A4, поэтому ингибиторы и индукторы этого изофермента, при одновременном применении, могут влиять на метаболизм и выведение лерканидипина. Не рекомендуется одновременное применение лерканидипина с ингибиторами CYP3A4 (кетоконазол, итраконазол, ритонавир, эритромицин, тролеандомицин). Не рекомендуется одновременное применение циклоспорина и лерканидипина, т.к. наблюдается увеличение концентрации обоих веществ в плазме крови. Следует проявлять осторожность при одновременном применении лерканидипина с другими субстратами CYP3A4 (терфенадин, астемизол, антиаритмические препараты III класса, например, амиодарон, хинидин). При одновременном применении лерканидипина в дозе 20 мг с мидазоламом биодоступность лерканидипина у пациентов пожилого возраста может увеличиваться приблизительно на 40%. Лерканидипин следует назначать с осторожностью одновременно с индукторами CYP3A4, например, противосудорожные средства (фенитоин, карбамазепин) и рифампицин, поскольку возможно снижение антигипертензивного действия препарата. Необходим регулярный контроль АД. При одновременном применении лерканидипина в дозе 20 мг у пациентов, постоянно принимающих бета-метилдигоксин, не было отмечено фармакокинетического взаимодействия, в то время как у здоровых добровольцев, которых лечили дигоксином, отмечалось увеличение значения Cmax для дигоксина в среднем на 33% после приема 20 мг лерканидипина натощак, при этом AUC и почечный клиренс изменялись незначительно. Необходимо контролировать наличие признаков интоксикации дигоксином у пациентов, принимающих одновременно дигоксин и лерканидипин. Одновременное применение лерканидипина с циметидином (до 800 мг) не вызывает значительных изменений концентрации лерканидипина в плазме крови. При высоких дозах циметидина могут увеличиваться биодоступность и антигипертензивное действие лерканидипина. При одновременном применении лерканидипина (20 мг) и симвастатина (40 мг), значение AUC для симвастатина увеличивалось на 56%, а это же значение для его активного метаболита - β-гидроксикислоты - на 28%. При приеме препаратов в разное время суток (лерканидипин - утром, симвастатин - вечером) можно избежать нежелательного взаимодействия. Возможно усиление антигипертензивного действия при одновременном приеме сока грейпфрута и лерканидипина. Этанол может потенцировать антигипертензивное действие лерканидипина."},{"name":"Регистрационный номер","value":"ЛП-№(001095)-(РГ-RU)"},{"name":"Дата государственной регистрации","value":"02.08.2022"},{"name":"Владелец регистрационного удостоверения","value":"Северная Звезда"},{"name":"Изготовитель","value":"Северная Звезда"},{"name":"Фасовщик","value":"Северная Звезда"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Лерканидипин-СЗ"},{"name":"Срок годности","value":"1 г."}]}],"transitionId":"tr_6"}}}}
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В случае выраженного снижения АД, потери сознания показана сердечно-сосудистая терапия, при брадикардии - внутривенное введение атропина. Информация об эффективности гемодиализа отсутствует. Учитывая высокую степень связи с белками плазмы крови, диализ может быть неэффективным.\u003Cbr\u003EИмеются данные о трех случаях передозировки при приеме лерканидипина в дозах 150 мг, 280 мг и 800 мг. Во всех случаях передозировки пациенты остались живы.\u003Cbr\u003EВ случае одновременного приема 150 мг лерканидипина с этанолом (неустановленное количество) наблюдалась сонливость. Лечение: промывание желудка, прием внутрь активированного угля.\u003Cbr\u003EВ случае одновременного приема 280 мг лерканидипина с 5,6 мг моксонидина наблюдались следующие симптомы: кардиогенный шок, выраженная ишемия миокарда, почечная недостаточность легкой степени. 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При применении совместно с индукторами CYP3A4 (в т.ч. с антидепрессантами, рифампицином) возможно уменьшение антигипертензивного действия лерканидипина. Возможно усиление гипотензивного эффекта лерканидипина при употреблении сока грейпфрута. Этанол может потенцировать действие лерканидипина. При одновременном применении с метопрололом, биодоступность лерканидипина уменьшается на 50%. Этот эффект может встречаться и при одновременном применении с другими бета-адреноблокаторами, поэтому может потребоваться коррекция дозы лерканидипина для достижения терапевтического эффекта при данной комбинации. Лерканидипин метаболизируется при участии изофермента CYP3A4, поэтому ингибиторы и индукторы этого изофермента, при одновременном применении, могут влиять на метаболизм и выведение лерканидипина. Не рекомендуется одновременное применение лерканидипина с ингибиторами CYP3A4 (кетоконазол, итраконазол, ритонавир, эритромицин, тролеандомицин). Не рекомендуется одновременное применение циклоспорина и лерканидипина, т.к. наблюдается увеличение концентрации обоих веществ в плазме крови. Следует проявлять осторожность при одновременном применении лерканидипина с другими субстратами CYP3A4 (терфенадин, астемизол, антиаритмические препараты III класса, например, амиодарон, хинидин). При одновременном применении лерканидипина в дозе 20 мг с мидазоламом биодоступность лерканидипина у пациентов пожилого возраста может увеличиваться приблизительно на 40%. Лерканидипин следует назначать с осторожностью одновременно с индукторами CYP3A4, например, противосудорожные средства (фенитоин, карбамазепин) и рифампицин, поскольку возможно снижение антигипертензивного действия препарата. Необходим регулярный контроль АД. При одновременном применении лерканидипина в дозе 20 мг у пациентов, постоянно принимающих бета-метилдигоксин, не было отмечено фармакокинетического взаимодействия, в то время как у здоровых добровольцев, которых лечили дигоксином, отмечалось увеличение значения Cmax для дигоксина в среднем на 33% после приема 20 мг лерканидипина натощак, при этом AUC и почечный клиренс изменялись незначительно. Необходимо контролировать наличие признаков интоксикации дигоксином у пациентов, принимающих одновременно дигоксин и лерканидипин. Одновременное применение лерканидипина с циметидином (до 800 мг) не вызывает значительных изменений концентрации лерканидипина в плазме крови. При высоких дозах циметидина могут увеличиваться биодоступность и антигипертензивное действие лерканидипина. При одновременном применении лерканидипина (20 мг) и симвастатина (40 мг), значение AUC для симвастатина увеличивалось на 56%, а это же значение для его активного метаболита - β-гидроксикислоты - на 28%. 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    Леркамен таб. п/о плен., 10 мг, 28 шт.

    Рейтинг товара: 4.73 из 5 на основе 15 оценок
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  • Леркамен таб. п/о плен., 20 мг, 28 шт.

    827 ₽

    Леркамен таб. п/о плен., 20 мг, 28 шт.

    Рейтинг товара: 5 из 5 на основе 5 оценок
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  • Лерканорм таб. п/о плен., 10 мг, 30 шт.
    Скидка: 11%
    –11 %

    417 ₽

    Вместо:467₽

    Лерканорм таб. п/о плен., 10 мг, 30 шт.

    Рейтинг товара: 4.8 из 5 на основе 10 оценок
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  • Лерканидипин таб. п/о плён., 10 мг, 30 шт.

    414 ₽

    Лерканидипин таб. п/о плён., 10 мг, 30 шт.

    Рейтинг товара: 5 из 5 на основе 1 оценка
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  • Леркамен Дуо таб. п/о плен., 10 мг+10 мг, 28 шт.

    690 ₽

    Леркамен Дуо таб. п/о плен., 10 мг+10 мг, 28 шт.

    Рейтинг товара: 4.35 из 5 на основе 23 оценки
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  • Занидип-Рекордати таб. п/о плен., 10 мг, 28 шт.

    425 ₽

    Занидип-Рекордати таб. п/о плен., 10 мг, 28 шт.

    Рейтинг товара: 5 из 5 на основе 4 оценки
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  • Лориста таб. п/о плен., 100 мг, 30 шт.

    201 ₽

    Лориста таб. п/о плен., 100 мг, 30 шт.

    Рейтинг товара: 4.88 из 5 на основе 33 оценки
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  • Моксонидин-СЗ таб. п/о плен., 0.3 мг, 28 шт.

    153 ₽

    Моксонидин-СЗ таб. п/о плен., 0.3 мг, 28 шт.

    Рейтинг товара: 4.7199996 из 5 на основе 18 оценок
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  • Кандесартан-СЗ таб., 16 мг, 30 шт.

    367 ₽

    Кандесартан-СЗ таб., 16 мг, 30 шт.

    Рейтинг товара: 5 из 5 на основе 2 оценки
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  • Аторвастатин-СЗ таб. п/о плен., 10 мг, 30 шт.

    136 ₽

    Аторвастатин-СЗ таб. п/о плен., 10 мг, 30 шт.

    Рейтинг товара: 4.86 из 5 на основе 35 оценок
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  • Телмисартан-СЗ таб., 40 мг, 30 шт.

    377 ₽

    Телмисартан-СЗ таб., 40 мг, 30 шт.

    Рейтинг товара: 4.71 из 5 на основе 7 оценок
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Инструкция

Показания к применению

Мягкая и умеренная эссенциальная артериальная гипертензия.

Противопоказания

Хроническая сердечная недостаточность в стадии декомпенсации; нестабильная стенокардия; аортальный стеноз; в течение 1 месяца после перенесенного инфаркта миокарда; выраженные нарушения функции печени; нарушение функции почек (КК менее 10 мл/мин); непереносимость лактозы; галактоземия; синдром нарушенного всасывания глюкозы/галактозы; беременность; период лактации (грудного вскармливания); женщины детородного возраста, не пользующиеся надежной контрацепцией; детский и подростковый возраст до 18 лет; повышенная чувствительность к компонентам препарата; повышенная чувствительность к другим производным дигидропиридинового ряда.

Способ применения и дозы

Внутрь по 10 мг 1 раз/сут не менее чем за 15 минут до еды, предпочтительно утром. В зависимости от достигнутого терапевтического эффекта доза может быть увеличена до 20 мг. Терапевтическую дозу подбирают постепенно, при необходимости, увеличение дозы до 20 мг осуществляется через 2 недели после начала лечения.
Полная инструкция
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Лерканидипин-СЗ таб. п/о плен.
Лерканидипин-СЗ таб. п/о плен., 20 мг, 60 шт., 1
5.0
(26)
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2 вопроса
Инструкция

714 ₽

Скидка: 21%
–21 %
Вместо:904 ₽
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5.0
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10 ноября 2023 • Анатолий Кузьмин
Достоинства: цена и качественноНедостатки: нетКомментарий: покупал для матери
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5 февраля • Марина С.
Достоинства: отличная ценаНедостатки: нет
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11 февраля 2023 • Имя скрыто
Достоинства: товар хорошийНедостатки: нет
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7 февраля 2022 • Инна Дьячкова
Достоинства: Меня он спасаетНедостатки: Нет
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  • Кандесартан-СЗ таб., 16 мг, 30 шт.
    367 ₽
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  • Аторвастатин-СЗ таб. п/о плен., 10 мг, 30 шт.
    136 ₽
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  • Телмисартан-СЗ таб., 40 мг, 30 шт.
    377 ₽
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  • Реклама
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    {"widgets":{"@marketfront/CreativeBanner":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_102_21/content/content/content":{"cpcLink":"/safeclick/data=SpQw45JhDGEtO5qMksCMdCT6PbT1wOtXqPHe_TGGhRPslBxUJDeUNPIevH84yEhdKFG4zXkMxe1KCI19EUnKCKCA-ijDQkhtrQBJQVu5X7s0Gu7OnfewQ3hcgpHowA-zLBjml2KkW45MdlH5uFhOWG0q7bMZIQjb_a-7FpWD9jicqEG8LHa9BhGhlzu4KpI47_YOhfKYeG-rVYOKIU5a4ZPGaqMe-pHpdNi48TcsbEfYUT_X_hsyX4jg99AltMac3uyOk0ZTyrW1btDxSiAdevQa9c-BJ2_kncHDrNldrLYv0UohgFJAXTkbKWHRvHPJPeO77j7VFrV4d87SsVLmrqoAsZaTH3P9zO0x5UysAwR4Ujih_d65pRb6nRxvb89gPpqHsv1B_Lwv-xQ7tozgs8EUFXwBDGmmbDYoJVN-ZuJn_FIhULdkqDafr_FqdFPib3dK5mjdb9feXlKySDjz2WnGTmRx2wushdg_IXaI1zSriUxJHceDpzew83yVwdpjAYeU9EtJGtIEzhaaXxWaLknwTs0K6RefeogtxLUsBlXBVPQWX20WgY1GXQVTAJGLQc7iHwZqB65QdtrrKrLSff-8_pwYuAfa8CKrJCd0GrulMpw3m5z3twtLQ1i-kM5cmPnlTGmcB7pflv3UxYq1Vya9cYIdINOvRzsyskSmncDci_OM2w3d05t161pw1-rMWz6TLwOIfWBlgvN8pCsiPeK66VIEt8xIcmm1lb0uNmbgf7BBE4hoK-CSAuizE9SkyGTIWzmzqKwjYsRFVdPoiB1yDJGb6xkKj5sATrR_6ru-Jq8rPyM-u0pQHI5Bv8T7P9u0F5ZZBEnuqbaIOacTDzfyMPwwwLOvEUbptkKOupR5J4rzvqzoKQv-BdB0kZ5NZXQLVdH-EM4ZHR_TWcijsljr3Rt7275KpjDevyeQOL5sETU3Al-742N14ZCZnsGNvfuVXhYNl57zaoWJUBe649_bxXVXxOIEAHRiPZ9ZJbDJTn6TIxwTmpN80DwuPGufbNWQyWqkvYC3IiqtKtIN1VlRCY810j1aI2u2QL7dMfTLR77c7bvsaWSigtjSeyniWmtTUd8ycob98WU1d6nJVPqpzTY4a3Lz-eob1SEMVYKCyUQmhJQ-hCM_MHb9o7t_lzJ2Wx-0RXyTrrqQ5o9ow5ZpMhNtXiWnRV5q3vTku3Ap5qITNhhJWLlllSL0r9-Uz6g07b5HvNtGUflfdQe5d0U78UdYDW6MqNbjFTT6wFadCd1tkmKd94K5A99ZY0xuY2Z76CzYOC_EEeSt1TESIs05h9wZbyPimnvlwYfO1trWuahBsclLllnnFff4y2Ayg2IBtMoK5SEmKPjz3M5DaJ-y52xUyQmq9udUvZpQHZnqLPdQmfNXoI6mkBdbH0Kzl1_duiDpbuGPTWJeE6RAwEJu_7PiritI6yemxShMdVnpRQlTx4amUPQGUZT7VOZiZz0UcDhdHK4rXnLkT-DdA_iKj_FP0gPKGNrf3qTbDT9evTNeTOj_Vb3U2QUSMATijEXDWBLlWNLeC06b3_a540FWpLlM7YQ0IdSimYsH2uRZSF43kcSecUpemHvOzqjrKYune5db2qWmE7Vy8lcq2d5EkvmiGKRBpy2BlleolYBSyVr8fbOu7JiXHm7f7Mxo5lSHLQaIrt4Kaa-kTHqa4E_ekruWjXKpAwSJn5TA55tFYrgKm5gK8WhB93I6hpHg5s4tOOLhYf4X9hcZq1eUcPS5v5cSP4TiPRmEPAhPWJl4QkBOPdGiUEXYKf_Qpu6oOiFKYzjlmY-OujVjtjOh8NuHm9f7qt1G9ynN_yrIa1lX9HVkBwjzye0_xRhTGFxz6iYvXdOTlyI-W1IkaPQk71ddFVbK9gLkrJCcF0iVY38svZ3rOY-dcET_ApH7ruues5gA4Zd3qK_BoqihrOGi2H4NryxDgSdFUM6dxxaHT5-sutiGa1zeYnc_Wa_62lvE9unxYsqOJyL0N2eEwueNTzP6IveKHsAFoXp9frVNB-4OtyulZwZSJ6xmBA5pcdMI5CEmljrhNNrsqChnLQ4uaagHCO9LUyH3sMBcerwl1G3nq6DIkbz4gelCMxMtH_WSPnJRkkf_lXD4y7fFgGPiNINcQJBNYjddx4fVr_LYNZ-NO5Xd-KDDueBmOr-KpXZZMVTyss1kGZQuCZrkLajaN3poDvF3u7tr/b64e=1/sign=2743c4af3ca984ebf9fbe58710f0944d/keyno=MARKET_1/*","url":"https://market.yandex.ru/special/maunfeld-may24?fromSins=1&erid=nyi26TK8Sq2EHejwvAWeYby8UswYAHXs","isClickoutExternal":true,"src":"https://avatars.mds.yandex.net/get-market-adv/8282799/83078581-d173-4c1f-911f-4556b95272fe/470x762","srcSet":"https://avatars.mds.yandex.net/get-market-adv/8282799/83078581-d173-4c1f-911f-4556b95272fe/470x762 1x, https://avatars.mds.yandex.net/get-market-adv/8282799/83078581-d173-4c1f-911f-4556b95272fe/940x1524 2x","showUrl":"/safeclick/data=SpQw45JhDGE6zDtOdUQO_JaPiEEmnmXyQC-TRYPAg5be-P4NUSbXONuMS7MV1x4eH4BI8BVykH7anW1DxoxSHLI_RtFT99lhLw8PWBKxXfMWSBjzJUraxYYA2fFhTUR_1932DRKkM7ZC8L2sEZ02-nwOCGL8B-9xpehMuE4g2c6LxNV4GGbAh1uzakoyhWArorrRieCr1xSv2MNUeDeWPVRSwgoLt1PfWlLYVV8KG4WbYe5rLz-F0Rtf_5X81uo1ZRP7u3OiSk54yC5KdDLgivpTmEhMBxq5g6-pieisIShcXIWUdz5MoX9UxcnFDRibFREGHtKAaEYW74Lai-ip0tcfg2nQokPDO8tKhkMCpi1qyMZ3-wqWiYM1hK4qnQXQr1s8GyEpMatGqnS6q-XYvmzgl90U7XlUMoOZ6V9aGD4-ByboxgaX3cnD-wD3i5-iF84qWXwv00INJDpGoQLqy2mmhIZY_cqfKkuD-cNUG2YLcV2QSjauHwFJhOo0BJuFouiyMTAyMJyBZfNRQEoz6DucVRXjGH9AjLeNNlc1_-D7dRBoyuN8aIzJdEDbRl9_Tqb8cuLQTPKJvnB_e3EdRUjrNdcwNfh9kmDjoomIggu1AFxj9jNJcnuE5UeXWHdNOqQN6qvYgv7Omg0tC1fBSup-13sCCq6aWFvFZgT6Nuq3wjWBHWX3f4PjQ3CmVkCZpid7fdcfUoUvIpsgDJbV4nQgFRSZM6BpS_syGe37wHyAOzCm5KgXhpn6pozCNt023PX_hlF-4lwUE8vERMWqWGviAPEN4dwYhttt70I4I7AxQ1FobO1o5hbDxyZ2dqFHql0Atp-EVM_E54PzqeFoSJZKsGxpK_vHPdUzeVfAKRHPYmVR281YCaRF4m9dSpw87AhCew50ZhupzKCg4ChJeh3QbtORfTyhqOHSc2Pcd1m-q5PcaONZMcQOKPj4uBrWxq3BoiVtwWkN0AOsMTiLm4F_kJoz2_ZfTOLO4-jzwmWOXW_cmIZemw,,/b64e=1/sign=575c2a08fea5cd642af0f87c30f507cc/keyno=MARKET_1/*","roundedCorners":true,"advertisementId":1673761,"fixedRatio":false,"height":762,"width":470,"billingTargetId":"5dyolydavfn_1673761","creativeType":"Banner","position":21,"isWhole":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_102_21/content/content/content":{"name":"@marketfront/CreativeBanner"}}}
  • Пастилки California Gold Nutrition Vitamin D3 gummies со вкусом фруктов и ягод, 280 г, 90 шт.

    Цена с картой Яндекс Пэй:411 ₽

    Вместо: 668 ₽
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  • Силденафил-СЗ таб. п/о плен., 25 мг, 20 шт.
    212 ₽ вместо 262
    {"widgets":{"@light/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1430912451_23/content/content/toggleWishlist":{"skuId":"228067804","size":18,"color":"#BDBDBC","wishlistLink":"/my/wishlist","withNotification":true,"withText":false}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1430912451_23/content/content/toggleWishlist":{"name":"@light/ToggleWishlist"}}}
    • {"widgets":{"@yandex-market/LazyLoader-market":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator":{"widgetName":"@marketfront/RecomLayout","widgetId":"ServerListRendererForSerp_RecommendationRoll","options":{"resolverParams":{"resources":{"garsons":[{"count":24,"limit":24,"params":{"cartProductIds":[],"snippetTypes":["product","product-block","category-block","advertisement","media-incut","promo-trigger","media-adv-banner-single","media-adv-banner-double","media-adv-carousel"],"program":"remix_desktop_model_card","hyperid":"1401075744"},"id":"RemixData"}],"shuffle":{"mode":"exclusive"}},"limit":24},"id":"RecommendationRoll","slotOptions":{"dynamic":true},"className":"","needToProvideData":true,"wrapperProps":{},"widgetOptions":{"config":{"pictureBlock":{"maxGalleryImagesCount":5},"descriptionBlock":{"order":1,"titleRowCount":"2"},"offerBlock":{"withGreenPrice":true,"order":2,"price":{"wrap":true,"overflow":"hidden"}}},"galleryImageSize":250},"layoutOptions":{"needFallbackOnError":true,"needFallbackOnEmpty":false,"countInRows":6},"isChefRemixExp":false},"slotOptions":{"dynamic":true},"placeholder":"Invisible","infinite":true,"cspNonce":"nYr0lc/0Yei4051B5i5v/g==","renderStrategy":"append","renderedOnce":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator":{"name":"@yandex-market/LazyLoader-market"}}}
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