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Описание

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Лонгидаза супп. д/ваг. и рект. введ., 3000 МЕ, 10 шт.

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4.8
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Коротко о товаре

Артикул Маркета
3123235066
Тип препарата
Назначение
Действующее вещество
Возраст
от 12 лет
Инструкция
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внутриматочные синехии, трубно¬перитонеальное бесплодие, хронический эндомиометрит;\u003Cbr\u003E- в дерматовенерологии: ограниченная склеродермия, профилактика фиброзных осложнений инфекций, передающихся половым путем;\u003Cbr\u003E- в хирургии: профилактика и лечение спаечного процесса после оперативных вмешательств на органах брюшной полости; длительно незаживающие раны;\u003Cbr\u003E- в пульмонологии и фтизиатрии: пневмофиброз, сидероз, туберкулез (кавернозно¬фиброзный, инфильтративный, туберкулема), интерстициальная пневмония, фиброзирующий альвеолит, плеврит;\u003Cbr\u003E- для увеличения биодоступности антибактериальной терапии в урологии, гинекологии, дерматовенерологии, хирургии, пульмонологии и др."},{"name":"Противопоказания","value":"- гиперчувствительность к препаратам на основе гиалуронидазы;\u003Cbr\u003E- легочное кровотечение и кровохарканье;\u003Cbr\u003E- свежее кровоизлияние в стекловидное тело;\u003Cbr\u003E- злокачественные новообразования;\u003Cbr\u003E- острая почечная недостаточность;\u003Cbr\u003E- детский возраст до 12 лет (результаты клинических исследований отсутствуют);\u003Cbr\u003E- беременность и период грудного вскармливания."},{"name":"Состав","value":"Состав на один суппозиторий:\u003Cbr\u003EАктивное вещество: Бовгиалуронидаза азоксимер (Лонгидаза) - 3000 ME.\u003Cbr\u003EВспомогательное вещество: масло какао - до получения суппозитория массой 1,3 г."},{"name":"Действующее вещество","value":"Бовгиалуронидаза азоксимер","transition":{"type":"catalog","params":{"categorySlug":"vaktsiny-syvorotki-fagi-toksiny","categoryId":"15756921","navnodeId":"72514","glfilters":["27144131:28709748"]}}},{"name":"Способ применения и дозы","value":"Лонгидаза суппозитории 3000 ME рекомендуется для ректального или вагинального применения один раз в сутки на ночь курсом от 10 до 20 введений.\u003Cbr\u003EПодросткам от 12 до 18 лет суппозитории вводятся только ректально.\u003Cbr\u003EВзрослым и подросткам старше 12 лет ректально: по 1 суппозиторию 1 раз в сутки после очищения кишечника.\u003Cbr\u003EВзрослым вагинально: по 1 суппозиторию 1 раз в сутки (на ночь) суппозиторий вводится во влагалище в положении лежа.\u003Cbr\u003EСхема введения корректируется в зависимости от тяжести, стадии и длительности заболевания: Лонгидаза назначается через день или с перерывами в 2-3 дня. Рекомендуемые схемы и дозы:\u003Cbr\u003E- в урологии: по 1 суппозиторию через день 10 введений, далее через 2-3 дня 10 введений, общим курсом 20 суппозиториев.\u003Cbr\u003E- в гинекологии: ректально или вагинально по 1 суппозиторию через 2 дня 10 введений, далее при необходимости назначается поддерживающая терапия.\u003Cbr\u003E- в дерматовенерологии: по 1 суппозиторию через 1-2 дня 10-15 введений.\u003Cbr\u003E- в хирургии: по 1 суппозиторию через 2-3 дня 10 введений.\u003Cbr\u003E- в пульмонологии и фтизиатрии: по 1 суппозиторию через 2-4 дня 10-20 введений. При необходимости рекомендуется повторный курс препарата Лонгидаза не ранее, чем через три месяца или длительная поддерживающая терапия по 1 суппозиторию 1 раз в 5-7 дней в течение 3-4 мес."},{"name":"Побочные действия","value":"Частота нежелательных реакций представлена по следующей классификации: очень частые ≥ 10 %; частые ≥ 1 % и \u003C 10%; нечастые ≥ 0,1 % и \u003C 1 %; редкие ≥ 0,01 % и \u003C 0,1 %; очень редкие \u003C 0,001 %.\u003Cbr\u003EОчень редко: местные реакции в виде покраснения, отека, зуда перианальной зоны, вагинального зуда в связи с индивидуальной чувствительностью к компонентам препарата."},{"name":"Фармакологическое действие","value":"Лонгидаза обладает гиалуронидазной (ферментативной) активностью пролонгированного действия, хелатирующими, антиоксидантными, иммуномодулирующими и умеренно выраженными противовоспалительными свойствами.\u003Cbr\u003EПролонгирование действия фермента достигается ковалентным связыванием фермента с физиологически активным полимерным носителем (азоксимер). Лонгидаза проявляет противофиброзные свойства, ослабляет течение острой фазы воспаления, регулирует (повышает или снижает в зависимости от исходного уровня) синтез медиаторов воспаления (интерлейкина-1 и фактора некроза опухоли - альфа), повышает гуморальный иммунный ответ и резистентность организма к инфекции.\u003Cbr\u003EВыраженные противофиброзные свойства Лонгидазы обеспечиваются конъюгацией гиалуронидазы с носителем, что значительно увеличивает устойчивость фермента к денатурирующим воздействиям и действию ингибиторов: ферментативная активность Лонгидазы сохраняется при нагревании до 37 °С в течение 20 суток, в то время как нативная гиалуронидаза в этих же условиях утрачивает свою активность в течение суток. В препарате Лонгидаза обеспечивается одновременное локальное присутствие фермента гиалуронидазы и носителя, способного связывать освобождающиеся при гидролизе компонентов матрикса ингибиторы фермента и стимуляторы синтеза коллагена (ионы железа, меди, гепарин и др.). Благодаря указанным свойствам Лонгидаза обладает не только способностью деполимеризовать матрикс соединительной ткани в фиброзно-гранулематозных образованиях, но и подавлять обратную регуляторную реакцию, направленную на синтез компонентов соединительной ткани.\u003Cbr\u003EСпецифическим субстратом тестикулярной гиалуронидазы являются гликозаминогликаны (гиалуроновая кислота, хондроитин, хондроитин-4-сульфат, хондроитин-6-сульфат), составляющие основу матрикса соединительной ткани. В результате деполимеризации (разрыва связи между С1 ацетилглюкозамина и С4 глюкуроновой или индуроновой кислот) гликозаминогликаны изменяют свои основные свойства: снижается вязкость, уменьшается способность связывать воду, ионы металлов, временно увеличивается проницаемость тканевых барьеров, облегчается движение жидкости в межклеточном пространстве, увеличивается эластичность соединительной ткани, что проявляется в уменьшении отечности ткани, уплощении рубцов, увеличении объема движения суставов, уменьшении контрактур и предупреждении их формирования, уменьшении спаечного процесса. Биохимическими, иммунологическими, гистологическими и электронно-микроскопическими исследованиями доказано, что Лонгидаза не повреждает нормальную соединительную ткань, а вызывает деструкцию измененной по составу и структуре соединительной ткани в области фиброза.\u003Cbr\u003EЛонгидаза не обладает мутагенным, эмбриотоксическим, тератогенным и канцерогенным действием.\u003Cbr\u003EПрепарат хорошо переносится пациентами, не отмечено местных и общих аллергических реакций.\u003Cbr\u003EПрименение Лонгидазы в терапевтических дозах во время или после оперативного лечения не вызывает ухудшение течения послеоперационного периода или прогрессирования инфекционного процесса; не замедляет восстановление костной ткани."},{"name":"Фармакологическая группа","value":"ферменты и антиферменты"},{"name":"Форма выпуска","value":"суппозитории вагинальные и ректальные"},{"name":"Способ применения/введения","value":"интравагинально, ректальный","transition":{"type":"catalog","params":{"categorySlug":"vaktsiny-syvorotki-fagi-toksiny","categoryId":"15756921","navnodeId":"72514","glfilters":["35947170:36763742,36763736"]}}},{"name":"Минимальный возраст применения","value":"от 12 лет"},{"name":"Условия хранения","value":"В сухом защищенном от света месте при температуре от 2 до 15 °С. Беречь от детей."},{"name":"Передозировка","value":"Симптомы передозировки могут проявляться ознобом, повышением температуры, головокружением, гипотензией. Введение препарата прекращают и назначают симптоматическую терапию."},{"name":"Применение при беременности и кормлении грудью","value":"Противопоказано применение при беременности и в период грудного вскармливания (клинический опыт применения отсутствует)."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Применение препарата Лонгидаза не влияет на способность управления транспортными средствами, обслуживание механизмов и другие виды работ, требующих повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"При приеме препарата неукоснительно следуйте данным в инструкции указаниям.\u003Cbr\u003EЕсли у вас возникнут вопросы, то обратитесь за разъяснением к вашему врачу или фармацевту.\u003Cbr\u003EПри развитии аллергической реакции прервать использование препарата Лонгидаза.\u003Cbr\u003EПри применении на фоне обострения очагов инфекции для предупреждения распространения инфекции необходимо назначать под прикрытием антимикробных средств.\u003Cbr\u003EПри появлении побочных реакций, а также при появлении побочной реакции, не упомянутой в инструкции медицинского применения необходимо обратиться к лечащему врачу.\u003Cbr\u003EНе использовать препарат при наличии визуальных признаков его непригодности (дефект упаковки, изменение цвета суппозитория).\u003Cbr\u003EВ случае пропуска введения очередной дозы препарата далее применять в обычном режиме (не вводить удвоенную дозу).\u003Cbr\u003EПри необходимости прекращения приема препарата Лонгидаза отмену можно осуществить сразу, без постепенного уменьшения дозы."},{"name":"Взаимодействие","value":"Препарат Лонгидаза можно комбинировать с антибиотиками, противовирусными, противогрибковыми препаратами, бронхолитиками. При назначении в комбинации с другими лекарственными средствами (антибиотики, местные анестетики, диуретики) следует учитывать возможность увеличения биодоступности и усиления их действия.\u003Cbr\u003EПри совместном применении с большими дозами салицилатов, кортизона, адренокортикотропного гормона (АКТГ), эстрогенов или антигистаминных препаратов может быть снижена ферментативная активность препарата Лонгидаза.\u003Cbr\u003EНе следует применять препарат Лонгидаза одновременно с препаратами, содержащими фуросемид, бензодиазепины, фенитоин."},{"name":"Регистрационный номер","value":"ЛCP-002940/07"},{"name":"Дата государственной регистрации","value":"11.08.2022"},{"name":"Владелец регистрационного удостоверения","value":"Petrovax","transition":{"type":"catalog","params":{"categorySlug":"vaktsiny-syvorotki-fagi-toksiny","categoryId":"15756921","navnodeId":"72514","glfilters":["34324371:35649313","7893318:15266591"]}}},{"name":"Изготовитель","value":"Петровакс фарм"},{"name":"Фасовщик","value":"Петровакс фарм"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Лонгидаза","transition":{"type":"catalog","params":{"categorySlug":"vaktsiny-syvorotki-fagi-toksiny","categoryId":"15756921","navnodeId":"72514","glfilters":["17796364:18033656"]}}},{"name":"Срок годности","value":"24 мес."}]}},"fullSpecsGrouped":{"17771976916627656282":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Органы и системы","value":"дыхательная система, кожа, половая система, половые железы"},{"name":"Назначение","value":"альвеолит, доброкачественная гиперплазия предстательной железы, плеврит, простатит, рубцы, синехии, склеродемия, спаечный процесс в малом тазу, стриктуры уретры и мочеточников, туберкулез, цистит"},{"name":"Показания к применению","value":"Взрослым и подросткам старше 12 лет в виде монотерапии и в составе комплексной терапии заболеваний, сопровождающихся гиперплазией соединительной ткани, в том числе и на фоне воспалительного процесса:\u003Cbr\u003E- в урологии: хронический простатит, интерстициальный цистит, стриктуры уретры и мочеточников, болезнь Пейрони, начальная стадия доброкачественной гиперплазии предстательной железы, профилактика образования рубцов и стриктур после оперативных вмешательств на уретре, мочевом пузыре, мочеточниках;\u003Cbr\u003E- в гинекологии: спаечный процесс (профилактика и лечение) в малом тазу при хронических воспалительных заболеваниях внутренних половых органов, после гинекологических манипуляций, в том числе искусственных абортов, перенесенных ранее оперативных вмешательств на органах малого таза; внутриматочные синехии, трубно¬перитонеальное бесплодие, хронический эндомиометрит;\u003Cbr\u003E- в дерматовенерологии: ограниченная склеродермия, профилактика фиброзных осложнений инфекций, передающихся половым путем;\u003Cbr\u003E- в хирургии: профилактика и лечение спаечного процесса после оперативных вмешательств на органах брюшной полости; длительно незаживающие раны;\u003Cbr\u003E- в пульмонологии и фтизиатрии: пневмофиброз, сидероз, туберкулез (кавернозно¬фиброзный, инфильтративный, туберкулема), интерстициальная пневмония, фиброзирующий альвеолит, плеврит;\u003Cbr\u003E- для увеличения биодоступности антибактериальной терапии в урологии, гинекологии, дерматовенерологии, хирургии, пульмонологии и др."},{"name":"Противопоказания","value":"- гиперчувствительность к препаратам на основе гиалуронидазы;\u003Cbr\u003E- легочное кровотечение и кровохарканье;\u003Cbr\u003E- свежее кровоизлияние в стекловидное тело;\u003Cbr\u003E- злокачественные новообразования;\u003Cbr\u003E- острая почечная недостаточность;\u003Cbr\u003E- детский возраст до 12 лет (результаты клинических исследований отсутствуют);\u003Cbr\u003E- беременность и период грудного вскармливания."},{"name":"Состав","value":"Состав на один суппозиторий:\u003Cbr\u003EАктивное вещество: Бовгиалуронидаза азоксимер (Лонгидаза) - 3000 ME.\u003Cbr\u003EВспомогательное вещество: масло какао - до получения суппозитория массой 1,3 г."},{"name":"Действующее вещество","value":"Бовгиалуронидаза азоксимер"},{"name":"Способ применения и дозы","value":"Лонгидаза суппозитории 3000 ME рекомендуется для ректального или вагинального применения один раз в сутки на ночь курсом от 10 до 20 введений.\u003Cbr\u003EПодросткам от 12 до 18 лет суппозитории вводятся только ректально.\u003Cbr\u003EВзрослым и подросткам старше 12 лет ректально: по 1 суппозиторию 1 раз в сутки после очищения кишечника.\u003Cbr\u003EВзрослым вагинально: по 1 суппозиторию 1 раз в сутки (на ночь) суппозиторий вводится во влагалище в положении лежа.\u003Cbr\u003EСхема введения корректируется в зависимости от тяжести, стадии и длительности заболевания: Лонгидаза назначается через день или с перерывами в 2-3 дня. Рекомендуемые схемы и дозы:\u003Cbr\u003E- в урологии: по 1 суппозиторию через день 10 введений, далее через 2-3 дня 10 введений, общим курсом 20 суппозиториев.\u003Cbr\u003E- в гинекологии: ректально или вагинально по 1 суппозиторию через 2 дня 10 введений, далее при необходимости назначается поддерживающая терапия.\u003Cbr\u003E- в дерматовенерологии: по 1 суппозиторию через 1-2 дня 10-15 введений.\u003Cbr\u003E- в хирургии: по 1 суппозиторию через 2-3 дня 10 введений.\u003Cbr\u003E- в пульмонологии и фтизиатрии: по 1 суппозиторию через 2-4 дня 10-20 введений. При необходимости рекомендуется повторный курс препарата Лонгидаза не ранее, чем через три месяца или длительная поддерживающая терапия по 1 суппозиторию 1 раз в 5-7 дней в течение 3-4 мес."},{"name":"Побочные действия","value":"Частота нежелательных реакций представлена по следующей классификации: очень частые ≥ 10 %; частые ≥ 1 % и \u003C 10%; нечастые ≥ 0,1 % и \u003C 1 %; редкие ≥ 0,01 % и \u003C 0,1 %; очень редкие \u003C 0,001 %.\u003Cbr\u003EОчень редко: местные реакции в виде покраснения, отека, зуда перианальной зоны, вагинального зуда в связи с индивидуальной чувствительностью к компонентам препарата."},{"name":"Фармакологическое действие","value":"Лонгидаза обладает гиалуронидазной (ферментативной) активностью пролонгированного действия, хелатирующими, антиоксидантными, иммуномодулирующими и умеренно выраженными противовоспалительными свойствами.\u003Cbr\u003EПролонгирование действия фермента достигается ковалентным связыванием фермента с физиологически активным полимерным носителем (азоксимер). Лонгидаза проявляет противофиброзные свойства, ослабляет течение острой фазы воспаления, регулирует (повышает или снижает в зависимости от исходного уровня) синтез медиаторов воспаления (интерлейкина-1 и фактора некроза опухоли - альфа), повышает гуморальный иммунный ответ и резистентность организма к инфекции.\u003Cbr\u003EВыраженные противофиброзные свойства Лонгидазы обеспечиваются конъюгацией гиалуронидазы с носителем, что значительно увеличивает устойчивость фермента к денатурирующим воздействиям и действию ингибиторов: ферментативная активность Лонгидазы сохраняется при нагревании до 37 °С в течение 20 суток, в то время как нативная гиалуронидаза в этих же условиях утрачивает свою активность в течение суток. В препарате Лонгидаза обеспечивается одновременное локальное присутствие фермента гиалуронидазы и носителя, способного связывать освобождающиеся при гидролизе компонентов матрикса ингибиторы фермента и стимуляторы синтеза коллагена (ионы железа, меди, гепарин и др.). Благодаря указанным свойствам Лонгидаза обладает не только способностью деполимеризовать матрикс соединительной ткани в фиброзно-гранулематозных образованиях, но и подавлять обратную регуляторную реакцию, направленную на синтез компонентов соединительной ткани.\u003Cbr\u003EСпецифическим субстратом тестикулярной гиалуронидазы являются гликозаминогликаны (гиалуроновая кислота, хондроитин, хондроитин-4-сульфат, хондроитин-6-сульфат), составляющие основу матрикса соединительной ткани. В результате деполимеризации (разрыва связи между С1 ацетилглюкозамина и С4 глюкуроновой или индуроновой кислот) гликозаминогликаны изменяют свои основные свойства: снижается вязкость, уменьшается способность связывать воду, ионы металлов, временно увеличивается проницаемость тканевых барьеров, облегчается движение жидкости в межклеточном пространстве, увеличивается эластичность соединительной ткани, что проявляется в уменьшении отечности ткани, уплощении рубцов, увеличении объема движения суставов, уменьшении контрактур и предупреждении их формирования, уменьшении спаечного процесса. Биохимическими, иммунологическими, гистологическими и электронно-микроскопическими исследованиями доказано, что Лонгидаза не повреждает нормальную соединительную ткань, а вызывает деструкцию измененной по составу и структуре соединительной ткани в области фиброза.\u003Cbr\u003EЛонгидаза не обладает мутагенным, эмбриотоксическим, тератогенным и канцерогенным действием.\u003Cbr\u003EПрепарат хорошо переносится пациентами, не отмечено местных и общих аллергических реакций.\u003Cbr\u003EПрименение Лонгидазы в терапевтических дозах во время или после оперативного лечения не вызывает ухудшение течения послеоперационного периода или прогрессирования инфекционного процесса; не замедляет восстановление костной ткани."},{"name":"Фармакологическая группа","value":"ферменты и антиферменты"},{"name":"Форма выпуска","value":"суппозитории вагинальные и ректальные"},{"name":"Способ применения/введения","value":"интравагинально, ректальный"},{"name":"Минимальный возраст применения","value":"от 12 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"В сухом защищенном от света месте при температуре от 2 до 15 °С. Беречь от детей."},{"name":"Передозировка","value":"Симптомы передозировки могут проявляться ознобом, повышением температуры, головокружением, гипотензией. Введение препарата прекращают и назначают симптоматическую терапию."},{"name":"Применение при беременности и кормлении грудью","value":"Противопоказано применение при беременности и в период грудного вскармливания (клинический опыт применения отсутствует)."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Применение препарата Лонгидаза не влияет на способность управления транспортными средствами, обслуживание механизмов и другие виды работ, требующих повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"При приеме препарата неукоснительно следуйте данным в инструкции указаниям.\u003Cbr\u003EЕсли у вас возникнут вопросы, то обратитесь за разъяснением к вашему врачу или фармацевту.\u003Cbr\u003EПри развитии аллергической реакции прервать использование препарата Лонгидаза.\u003Cbr\u003EПри применении на фоне обострения очагов инфекции для предупреждения распространения инфекции необходимо назначать под прикрытием антимикробных средств.\u003Cbr\u003EПри появлении побочных реакций, а также при появлении побочной реакции, не упомянутой в инструкции медицинского применения необходимо обратиться к лечащему врачу.\u003Cbr\u003EНе использовать препарат при наличии визуальных признаков его непригодности (дефект упаковки, изменение цвета суппозитория).\u003Cbr\u003EВ случае пропуска введения очередной дозы препарата далее применять в обычном режиме (не вводить удвоенную дозу).\u003Cbr\u003EПри необходимости прекращения приема препарата Лонгидаза отмену можно осуществить сразу, без постепенного уменьшения дозы."},{"name":"Взаимодействие","value":"Препарат Лонгидаза можно комбинировать с антибиотиками, противовирусными, противогрибковыми препаратами, бронхолитиками. При назначении в комбинации с другими лекарственными средствами (антибиотики, местные анестетики, диуретики) следует учитывать возможность увеличения биодоступности и усиления их действия.\u003Cbr\u003EПри совместном применении с большими дозами салицилатов, кортизона, адренокортикотропного гормона (АКТГ), эстрогенов или антигистаминных препаратов может быть снижена ферментативная активность препарата Лонгидаза.\u003Cbr\u003EНе следует применять препарат Лонгидаза одновременно с препаратами, содержащими фуросемид, бензодиазепины, фенитоин."},{"name":"Регистрационный номер","value":"ЛCP-002940/07"},{"name":"Дата государственной регистрации","value":"11.08.2022"},{"name":"Владелец регистрационного удостоверения","value":"Petrovax"},{"name":"Изготовитель","value":"Петровакс фарм"},{"name":"Фасовщик","value":"Петровакс фарм"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Лонгидаза"},{"name":"Срок годности","value":"24 мес."}]}],"transitionId":"tr_8030772361331110824"}}}}
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Инструкция

Показания к применению

Взрослым и подросткам старше 12 лет в виде монотерапии и в составе комплексной терапии заболеваний, сопровождающихся гиперплазией соединительной ткани, в том числе и на фоне воспалительного процесса:
- в урологии: хронический простатит, интерстициальный цистит, стриктуры уретры и мочеточников, болезнь Пейрони, начальная стадия доброкачественной гиперплазии предстательной железы, профилактика образования рубцов и стриктур после оперативных вмешательств на уретре, мочевом пузыре, мочеточниках;
- в гинекологии: спаечный процесс (профилактика и лечение) в малом тазу при хронических воспалительных заболеваниях внутренних половых органов, после гинекологических манипуляций, в том числе искусственных абортов, перенесенных ранее оперативных вмешательств на органах малого таза; внутриматочные синехии, трубно¬перитонеальное бесплодие, хронический эндомиометрит;
- в дерматовенерологии: ограниченная склеродермия, профилактика фиброзных осложнений инфекций, передающихся половым путем;
- в хирургии: профилактика и лечение спаечного процесса после оперативных вмешательств на органах брюшной полости; длительно незаживающие раны;
- в пульмонологии и фтизиатрии: пневмофиброз, сидероз, туберкулез (кавернозно¬фиброзный, инфильтративный, туберкулема), интерстициальная пневмония, фиброзирующий альвеолит, плеврит;
- для увеличения биодоступности антибактериальной терапии в урологии, гинекологии, дерматовенерологии, хирургии, пульмонологии и др.

Противопоказания

- гиперчувствительность к препаратам на основе гиалуронидазы;
- легочное кровотечение и кровохарканье;
- свежее кровоизлияние в стекловидное тело;
- злокачественные новообразования;
- острая почечная недостаточность;
- детский возраст до 12 лет (результаты клинических исследований отсутствуют);
- беременность и период грудного вскармливания.

Способ применения и дозы

Лонгидаза суппозитории 3000 ME рекомендуется для ректального или вагинального применения один раз в сутки на ночь курсом от 10 до 20 введений.
Подросткам от 12 до 18 лет суппозитории вводятся только ректально.
Взрослым и подросткам старше 12 лет ректально: по 1 суппозиторию 1 раз в сутки после очищения кишечника.
Взрослым вагинально: по 1 суппозиторию 1 раз в сутки (на ночь) суппозиторий вводится во влагалище в положении лежа.
Схема введения корректируется в зависимости от тяжести, стадии и длительности заболевания: Лонгидаза назначается через день или с перерывами в 2-3 дня. Рекомендуемые схемы и дозы:
- в урологии: по 1 суппозиторию через день 10 введений, далее через 2-3 дня 10 введений, общим курсом 20 суппозиториев.
- в гинекологии: ректально или вагинально по 1 суппозиторию через 2 дня 10 введений, далее при необходимости назначается поддерживающая терапия.
- в дерматовенерологии: по 1 суппозиторию через 1-2 дня 10-15 введений.
- в хирургии: по 1 суппозиторию через 2-3 дня 10 введений.
- в пульмонологии и фтизиатрии: по 1 суппозиторию через 2-4 дня 10-20 введений. При необходимости рекомендуется повторный курс препарата Лонгидаза не ранее, чем через три месяца или длительная поддерживающая терапия по 1 суппозиторию 1 раз в 5-7 дней в течение 3-4 мес.
Полная инструкция
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Лонгидаза супп. д/ваг. и рект. введ.
Лонгидаза супп. д/ваг. и рект. введ., 3000 МЕ, 10 шт.
4.8
(242)
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27 вопросов
Инструкция

Цена с картой Яндекс Пэй:2 594 ₽

Скидка: 1%
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Вместо: 2 620 ₽
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4.8
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У продавца:242 оценки·32 отзыва
У всех продавцов:978 оценок·277 отзывов
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user avatar
4 месяца назад • Сергей Еременко • Куплен на Маркете
Достоинства: Это средство работает по назначению.
Недостатки: Цена высокая
Комментарий: Ну что говорить, мужики. У каждого из нас рано или поздно проблемы интимного характера возникают. По назначению врача купил Лонгидазу. Эффект есть. Не то, чтобы взрывной, но ощутимый. Периодически надо повторять курс применения. В этой связи, конечно хотелось бы, чтобы он был более доступным по цене.
user avatar
4 месяца назад • Ekaterina L. • Куплен на Маркете
Достоинства: пользуюсь давно в связи со спаечным образованием, назначено врачем гинекологом.
Недостатки: жаль нет аналога дешевле,очень дорогой
Комментарий: в моем случае отличное лекарство.
user avatar
4 месяца назад • Lina261282 • Куплен на Маркете
Достоинства: Выписали по назначению, побочек нет
Недостатки: Все хорошо, недостатков нет
Комментарий: Выписали по назначению, купила сразу две пачки. Цена оптимальная, спасибо сплиту
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  • Витапрост супп. рект., 10 мг, 10 шт.
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    Витапрост супп. рект., 10 мг, 10 шт.

    Цена 1 399 ₽ вместо 1 413
  • Лонгидаза лиоф. д/приг. р-ра д/ин., 3000 МЕ, 5 шт.
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    Лонгидаза лиоф. д/приг. р-ра д/ин., 3000 МЕ, 5 шт.

    Цена 3 840 ₽ вместо 4 315
  • Алфупрост МР таб. пролонг. высвоб., 10 мг, 30 шт.
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    Алфупрост МР таб. пролонг. высвоб., 10 мг, 30 шт.

    Цена 313 ₽
  • Витапрост форте супп. рект., 20 мг, 10 шт.
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    Витапрост форте супп. рект., 20 мг, 10 шт.

    Цена 2 014 ₽ вместо 2 034
  • Простамол Уно капс., 320 мг, 30 шт.
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    Простамол Уно капс., 320 мг, 30 шт.

    Цена 955 ₽ вместо 965
  • Отофаг гель с бактериофагами фл., 50 мл
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    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778176423_5/content/content/toggleWishlist":{"skuId":"653884186","productId":1778176423,"offerId":"7h3VXpXUJC3ov3yNDciQxw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQpNXq5Pyy9OxmEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCKej888GEJr25bcCGK7sxAgg+dzBBw==","sign":"WZmuT2mZoRtC36UGiZEpoXDNDKptoIcpvJNNPJ/RpUY="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778176423_5/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Отофаг гель с бактериофагами фл., 50 мл

    Цена 1 091 ₽
  • Простатекс суп. рект., 10 мг, 10 шт.
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    Простатекс суп. рект., 10 мг, 10 шт.

    Цена 1 127 ₽ вместо 1 138
  • Витапрост таб. п/о кш/раств., 20 мг, 20 шт.
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    Витапрост таб. п/о кш/раств., 20 мг, 20 шт.

    Цена 2 078 ₽ вместо 2 099
  • Реклама
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    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  • Пиобактериофаг поливалентный очищенный р-р д/вн. приема, местн. и нар. прим. фл., 20 мл, 4 шт.
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    Пиобактериофаг поливалентный очищенный р-р д/вн. приема, местн. и нар. прим. фл., 20 мл, 4 шт.

    Цена 1 154 ₽ вместо 1 294
  • Афалаза таб. д/рассас., 100 шт.
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    Афалаза таб. д/рассас., 100 шт.

    Цена 995 ₽ вместо 1 005
  • Джадену таб. п/о плен., 180 мг, 90 шт.
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    Джадену таб. п/о плен., 180 мг, 90 шт.

    Цена 31 509 ₽
  • Бестфертил капс., 120 шт.
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    Бестфертил капс., 120 шт.

    Цена 5 084 ₽
  • Суперлимф супп. ваг. и рект., 25 ЕД, 10 шт., 1 уп.
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    Суперлимф супп. ваг. и рект., 25 ЕД, 10 шт., 1 уп.

    Цена 2 066 ₽ вместо 2 525
  • Сыворотка противостолбнячная р-р для ин. амп., 3000 МЕ, 5 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778177317_14/content/content/gallery":{"title":"Сыворотка противостолбнячная р-р для ин. амп., 3000 МЕ, 5 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/5235334/img_id2032251753145507412.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5235334/img_id2032251753145507412.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5235334/img_id2032251753145507412.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5235334/img_id2032251753145507412.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5235334/img_id2032251753145507412.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5235334/img_id2032251753145507412.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4561793/img_id636401556274594367.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4561793/img_id636401556274594367.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4561793/img_id636401556274594367.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4561793/img_id636401556274594367.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4561793/img_id636401556274594367.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4561793/img_id636401556274594367.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQpNXq5Pyy9OxmEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIVCKWq888GEN2F4WwYjODQByD53MEH","sign":"j09Ipc7kgrO5NN3/lCuWiXhbFFCrdt3M/IdOa+xwY9U="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778177317_14/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
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    Сыворотка противостолбнячная р-р для ин. амп., 3000 МЕ, 5 шт.

    Цена 915 ₽
  • ПростаНорм таб. п/о, 200 мг, 30 шт.
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    ПростаНорм таб. п/о, 200 мг, 30 шт.

    Цена 405 ₽ вместо 409
  • Таваник таб. п/о плен., 500 мг, 5 шт.
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    Таваник таб. п/о плен., 500 мг, 5 шт.

    Цена 369 ₽
  • Налоксон р-р д/ин. амп., 0.4 мг/мл, 1 мл, 10 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778177289_17/content/content/toggleWishlist":{"skuId":"186889027","productId":1778177289,"offerId":"IO9e8xnD2j7-Xxu2p6M5cg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQpNXq5Pyy9OxmEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIVCImq888GEMPmjlkYytzQByD53MEH","sign":"TtO5FtzvtrhzN3l73A7sqnDjDGvW/Db1PAem6bzb4TI="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778177289_17/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Налоксон р-р д/ин. амп., 0.4 мг/мл, 1 мл, 10 шт.

    Цена 234 ₽ вместо 284
  • Простатилен супп. рект., 30 мг, 10 шт.
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    Простатилен супп. рект., 30 мг, 10 шт.

    Цена 989 ₽ вместо 999
  • Пермиксон капс., 160 мг, 30 шт.
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    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778175565_19/content/content/toggleWishlist":{"skuId":"228066208","productId":1778175565,"offerId":"CtiyaR5xSlcceAMoGgcfBA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQpNXq5Pyy9OxmEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIVCM2c888GEKCH4GwY4Pm5CCDu3MEH","sign":"UbkAmIraEVQfJ1pwB6bxwNFwhPoVdsiJv0Yexh/v83s="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778175565_19/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Пермиксон капс., 160 мг, 30 шт.

    Цена 1 028 ₽ вместо 1 038
  • Омник окас таб. контр. высвоб. п/о, 0.4 мг, 30 шт.
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    Омник окас таб. контр. высвоб. п/о, 0.4 мг, 30 шт.

    Цена 826 ₽ вместо 958
  • Реклама
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  • Клебсифаг р-р д/вн. приема, мест. и нар.прим. фл., 20 мл, 4 шт.
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    Клебсифаг р-р д/вн. приема, мест. и нар.прим. фл., 20 мл, 4 шт.

    Цена 1 355 ₽ вместо 1 716
  • Анатоксин столбнячный (ас-анатоксин) сусп. для п/к введ. дозы, 10 шт.
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    Анатоксин столбнячный (ас-анатоксин) сусп. для п/к введ. дозы, 10 шт.

    Цена 890 ₽
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