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Описание

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Мальтофер капли д/вн. приема, 50 мг/мл, 1 шт.

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5.0
(31)
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Коротко о товаре

Артикул Маркета
2101308907735
Дозировка
Объем
30 мл
Количество штук в упаковке
1 шт.
Тип препарата
Инструкция
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Структура многоядерного ядра железа (III) гидроксид полимальтозата сходна со структурой ядра белка ферритина - (физиологического депо железа. Железа (III) гидроксид полимальтозат стабилен и в физиологических условиях не выделяет большого количества ионов железа. Из-за размера степень диффузии железа (III) гидроксид полимальтозата через слизистую оболочку приблизительно в 40 раз меньше по сравнению с комплексом шестиводного железа (II). 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Существенного снижения всасывания тетрациклина не наблюдалось. Концентрация тетрациклина в плазме крови не опускалась ниже эффективного уровня. Всасывание железа из железа (III) гидроксид полимальтозата не снижалось под влиянием алюминия гидроксида или тетрациклина. Таким образом, железа (III) гидроксид полимальтозат можно применять одновременно с тетрациклином и другими фенольными соединениями, а также с гидроксидом алюминия.\u003Cbr\u003EВ исследованиях у крыс с использованием тетрациклина, гидроксида алюминия, ацетилсалициловой кислоты, сульфасалазина, кальция карбоната, кальция ацетата и кальция фосфата в комбинации с витамином D3, бромазепама, магния аспартата, D-пеницилламина, метилдопы, парацетамола и ауранофина не было обнаружено взаимодействия с железа (III) гидроксид полимальтозатом.\u003Cbr\u003EТакже не отмечено взаимодействия железа (III) гидроксид полимальтозата с компонентами продуктов питания, такими, как фитиновая кислота, щавелевая кислота, танин, натрия альгинат, холин и холиновые соли, витамин А, витамин D3 и витамин Е, соевое масло и соевая мука. Данные результаты свидетельствуют о том, что железа (III) гидроксид полимальтозат можно принимать во время или сразу же после приема пищи.\u003Cbr\u003EПрием препарата не оказывает влияния на результаты определения скрытой крови (с селективным определением гемоглобина), поэтому нет необходимости прерывать лечение.\u003Cbr\u003EНеобходимо избегать одновременного применения препаратов железа для парентерального введения и приема внутрь, поскольку всасывание железа, принимаемого внутрь, замедляется."},{"name":"Показания к применению","value":"Лечение дефицита железа без анемии (латентного дефицита железа) и лечение клинически выраженной железодефицитной анемии (см. раздел \"Способ применения и дозы\").\u003Cbr\u003EПрофилактика дефицита железа во время беременности и в период грудного вскармливания; у женщин детородного возраста, у детей, в подростковом возрасте и у взрослых (например, вегетарианцев и пожилых людей)."},{"name":"Противопоказания","value":"Установленная гиперчувствительность к железа (III) гидроксид полимальтозату или к любому вспомогательному веществу.\u003Cbr\u003EПерегрузка железом (например, гемосидероз, гемохроматоз).\u003Cbr\u003EНарушение утилизации железа (например, свинцовая анемия, сидероахрестическая анемия, талассемия).\u003Cbr\u003EАнемия, не связанная с дефицитом железа (например, гемолитическая анемия или мегалобластная анемия, вызванная недостатком витамина B12).\u003Cbr\u003EДефицит сахаразы/изомальтазы, непереносимость фруктозы, глюкозо-галактозная мальабсорбция."},{"name":"Способ применения и дозы","value":"Для приема внутрь.\u003Cbr\u003EСуточную дозу можно разделить на несколько приемов или принимать за один раз. Мальтофер следует принимать во время или сразу же после приема пиши.\u003Cbr\u003EМальтофер можно смешивать с фруктовыми и овощными соками, или с детской пищей, или молочной детской смесью, или неалкогольными напитками. Лёгкое окрашивание смеси не оказывает влияния ни на вкус сока/детского питания, ни на эффективность препарата.\u003Cbr\u003EДля точного отмеривания дозы препарата флакон/контейнер (тубу) следует держать вертикально. Капли должны вытекать сразу же. Если этого не происходит, слегка постучите по флакону/контейнеру (тубе) до появления капли. Не встряхивайте флакон/контейнер (тубу).\u003Cbr\u003EЛечение железодефицитной анемии у детей и взрослых\u003Cbr\u003EЛечение до достижения нормального содержания гемоглобина (Hb) занимает приблизительно от 3 до 5 месяцев. После этого лечение следует продолжить в течение 1-2 месяцев в дозе, описанной для случая дефицита железа без анемии, с целью восполнения запасов железа.\u003Cbr\u003EЛечение железодефицитной анемии во время беременности\u003Cbr\u003EЛечение следует продолжать до нормализации содержания гемоглобина (Hb). После этого лечение следует продолжить как минимум до конца беременности в дозе, описанной для случая дефицита железа без анемии, с целью восполнения запасов железа и удовлетворения возросших в связи с беременностью потребностей в железе.\u003Cbr\u003EЛечение и предупреждение дефицита железа без анемии\u003Cbr\u003EЛечение занимает приблизительно от 1 до 2 месяцев."},{"name":"Применение при беременности","value":"Беременность\u003Cbr\u003EДо настоящего времени не поступало сообщений о серьезных нежелательных реакциях после приёма препарата Мальтофер внутрь в терапевтических дозах при лечении анемии во время беременности. Данные, полученные при исследованиях на животных, не показали опасности для плода и матери. Данные клинических исследований о применении препарата Мальтофер в I триместре беременности отсутствуют.\u003Cbr\u003EВ исследованиях, проведенных у беременных женщин после окончания I триместра беременности, не обнаружено никаких нежелательных эффектов препарата Мальтофер в отношении матерей и/или новорожденных. В связи с этим неблагоприятное влияние на плод при применении препарата Мальтофер маловероятно.\u003Cbr\u003EПериод грудного вскармливания\u003Cbr\u003EГрудное молоко женщины содержит железо, связанное с лактоферрином. Количество железа, переходящего из железа (III) гидроксид полимальтозата в грудное молоко, неизвестно. Маловероятно, что применение препарата Мальтофер женщинами, кормящими грудью, способно привести к нежелательным эффектам у ребенка.\u003Cbr\u003EВ качестве меры предосторожности женщинам детородного возраста и женщинам в период беременности и грудного вскармливания следует принимать препарат Мальтофер только после консультации с врачом. Рекомендуется проводить оценку соотношения пользы и риска."},{"name":"Побочные действия","value":"Безопасность и переносимость препарата Мальтофер была оценена во множестве клинических исследований.\u003Cbr\u003EЧастота побочных явлений определялась следующим образом: очень часто (≥1/10), часто (≥1/100, \u003C1/10), нечасто (≥1/1000, \u003C1/100).\u003Cbr\u003EОсновные нежелательные лекарственные реакции, отмеченные в данных исследованиях, имели место в следующих трех классах систем и органов.\u003Cbr\u003EНежелательные лекарственные реакции, наблюдавшиеся в клинических исследованиях\u003Cbr\u003EСо стороны нервной системы: нечасто - головная боль.\u003Cbr\u003EСо стороны пищеварительной системы: очень часто - изменение цвета кала1; часто - диарея, тошнота, диспепсия; нечасто - рвота, запор, боль в животе, изменение цвета эмали зубов2.\u003Cbr\u003EСо стороны кожи и подкожных тканей: нечасто - сыпь, зуд.\u003Cbr\u003E. Часто регистрировали как нежелательное явление (у 23% пациентов), это хорошо известная нежелательная лекарственная реакция на препараты железа для приема внутрь.\u003Cbr\u003E2. Регистрировали как нежелательное явление у 0.6% пациентов, это хорошо известная нежелательная лекарственная реакция на препараты железа для приема внутрь.\u003Cbr\u003E. Включая экзантему.\u003Cbr\u003EСпонтанные постмаркетинговые сообщения о нежелательных лекарственных реакциях\u003Cbr\u003EНе отмечено дополнительных нежелательных лекарственных реакций.\u003Cbr\u003EОтклонения лабораторных показателей\u003Cbr\u003EДанные отсутствуют."},{"name":"Передозировка","value":"В случае передозировки препаратом Мальтофер перегрузка железом или интоксикация маловероятны, что связано с низкой токсичностью железа (III) гидроксид полимальтозата и контролируемым захватом железа. О случаях непреднамеренного отравления с летальным исходом не сообщалось.\u003Cbr\u003EВзаимодействие:\u003Cbr\u003EБыли изучены взаимодействия железа (III) гидроксид полимальтозата с тетрациклином или гидроксидом алюминия. Существенного снижения всасывания тетрациклина не наблюдалось. Концентрация тетрациклина в плазме крови не опускалась ниже эффективного уровня. Всасывание железа из железа (III) гидроксид полимальтозата не снижалось под влиянием алюминия гидроксида или тетрациклина. Таким образом, железа (III) гидроксид полимальтозат можно применять одновременно с тетрациклином и другими фенольными соединениями, а также с гидроксидом алюминия.\u003Cbr\u003EВ исследованиях у крыс с использованием тетрациклина, гидроксида алюминия, ацетилсалициловой кислоты, сульфасалазина, кальция карбоната, кальция ацетата и кальция фосфата в комбинации с витамином D3, бромазепама, магния аспартата, D-пеницилламина, метилдопы, парацетамола и ауранофина не было обнаружено взаимодействий с железа (III) гидроксид полимальтозатом.\u003Cbr\u003EТакже не отмечено взаимодействия железа(III) гидроксид полимальтозата с компонентами продуктов питания, такими, как фитиновая кислота, щавелевая кислота, танин, натрия альгинат, холин и холиновые соли, витамин А, витамин D3 и витамин Е, соевое масло и соевая мука. Данные результаты свидетельствуют о том, что железа (III) гидроксид полимальтозат можно принимать во время или сразу же после приёма пищи.\u003Cbr\u003EПриём препарата не оказывает влияния на результаты определения скрытой крови (с селективным определением гемоглобина), поэтому прерывать лечение не нужно. Необходимо избегать одновременного применения парентеральных и пероральных препаратов железа, поскольку всасывание железа, принимаемого внутрь, замедляется."},{"name":"Условия хранения","value":"При температуре не выше 25°С в защищенном от света месте.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Особые указания","value":"Предполагается, что прием препарата Мальтофер не должен оказывать влияния на суточную потребность в инсулине у пациентов с сахарным диабетом. 1 мл капель содержит 0,01 хлебных единиц.\u003Cbr\u003EАнемия может быть вызвана инфекционными заболеваниями или злокачественными новообразованиями. Поскольку железо можно принимать лишь после устранения основной причины заболевания, следует определить соотношение пользы и риска лечения.\u003Cbr\u003EВо время лечения препаратом Мальтофер может отмечаться тёмное окрашивание кала, однако это не имеет клинического значения.\u003Cbr\u003EМальтофер содержит сахарозу, которая может нанести вред зубам.\u003Cbr\u003EВспомогательные вещества натрия метилпарагидроксибензоат и натрия пропилпарагидроксибензоат могут вызывать аллергические реакции (возможно, замедленного типа)."},{"name":"Страна бренда","value":"Швейцария"},{"name":"Страна производства","value":"Швейцария"},{"name":"Владелец регистрационного удостоверения","value":"Вифор"},{"name":"Изготовитель","value":"Вифор"},{"name":"Фасовщик","value":"Вифор"}]}},"fullSpecsGrouped":{"6371527065633301451":{"groups":[{"name":"Регистрационные данные","items":[{"name":"Дозировка","value":"50 мг/мл"},{"name":"Объем","value":"30 мл"},{"name":"Количество штук в упаковке","value":"1 шт."}]},{"name":"Тип препарата","items":[{"name":"Особенности","value":"для детей"},{"name":"Рецептурный препарат","value":"да"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Форма выпуска","value":"капли"}]},{"name":"Применение и информация","items":[{"name":"Является ЖНВЛС","value":"да"},{"name":"Действующее вещество","value":"Железа (III) гидроксид полимальтозат"},{"name":"Фармакологическая группа","value":"железа препарат"},{"name":"Фармакологическое действие","value":"В железа (III) гидроксид полимальтозате многоядерный гидроксид железа (III) снаружи окружен множеством ковалентно связанных молекул полимальтозата, что даёт общую среднюю молекулярную массу приблизительно 50 кДа. Структура многоядерного ядра железа (III) гидроксид полимальтозата сходна со структурой ядра белка ферритина - (физиологического депо железа. Железа (III) гидроксид полимальтозат стабилен и в физиологических условиях не выделяет большого количества ионов железа. Из-за размера степень диффузии железа (III) гидроксид полимальтозата через слизистую оболочку приблизительно в 40 раз меньше по сравнению с комплексом шестиводного железа (II). Железо из железа (III) гидроксид полимальтозата активно всасывается в кишечнике.\u003Cbr\u003EЭффективность препарата Мальтофер для нормализации содержания гемоглобина и восполнения депо железа была продемонстрирована в многочисленных рандомизированных контролируемых клинических исследованиях с использованием плацебо-контроля или активного препарата сравнения, проведенных у взрослых и детей с различным статусом депо железа."},{"name":"Состав","value":"Действующее вещество: железо (в форме комплекса гидроксида железа (III) с полимальтозой) – 2.5 мг\u003Cbr\u003EВспомогательные вещества: сахароза – 50 мг, метилпарагидроксибензоат натрия – 2 мг, пропилпарагидроксибензоат натрия – 0.22 мг, ароматизатор кремовый – 3 мг, натрия гидроксид – до pH 5.5-7.0, вода очищенная – до 1 мл\u003Cbr/\u003E"},{"name":"Взаимодействие","value":"Было изучено взаимодействие железа (III) гидроксид полимальтозата с тетрациклином и гидроксидом алюминия. Существенного снижения всасывания тетрациклина не наблюдалось. Концентрация тетрациклина в плазме крови не опускалась ниже эффективного уровня. Всасывание железа из железа (III) гидроксид полимальтозата не снижалось под влиянием алюминия гидроксида или тетрациклина. Таким образом, железа (III) гидроксид полимальтозат можно применять одновременно с тетрациклином и другими фенольными соединениями, а также с гидроксидом алюминия.\u003Cbr\u003EВ исследованиях у крыс с использованием тетрациклина, гидроксида алюминия, ацетилсалициловой кислоты, сульфасалазина, кальция карбоната, кальция ацетата и кальция фосфата в комбинации с витамином D3, бромазепама, магния аспартата, D-пеницилламина, метилдопы, парацетамола и ауранофина не было обнаружено взаимодействия с железа (III) гидроксид полимальтозатом.\u003Cbr\u003EТакже не отмечено взаимодействия железа (III) гидроксид полимальтозата с компонентами продуктов питания, такими, как фитиновая кислота, щавелевая кислота, танин, натрия альгинат, холин и холиновые соли, витамин А, витамин D3 и витамин Е, соевое масло и соевая мука. Данные результаты свидетельствуют о том, что железа (III) гидроксид полимальтозат можно принимать во время или сразу же после приема пищи.\u003Cbr\u003EПрием препарата не оказывает влияния на результаты определения скрытой крови (с селективным определением гемоглобина), поэтому нет необходимости прерывать лечение.\u003Cbr\u003EНеобходимо избегать одновременного применения препаратов железа для парентерального введения и приема внутрь, поскольку всасывание железа, принимаемого внутрь, замедляется."},{"name":"Показания к применению","value":"Лечение дефицита железа без анемии (латентного дефицита железа) и лечение клинически выраженной железодефицитной анемии (см. раздел \"Способ применения и дозы\").\u003Cbr\u003EПрофилактика дефицита железа во время беременности и в период грудного вскармливания; у женщин детородного возраста, у детей, в подростковом возрасте и у взрослых (например, вегетарианцев и пожилых людей)."},{"name":"Противопоказания","value":"Установленная гиперчувствительность к железа (III) гидроксид полимальтозату или к любому вспомогательному веществу.\u003Cbr\u003EПерегрузка железом (например, гемосидероз, гемохроматоз).\u003Cbr\u003EНарушение утилизации железа (например, свинцовая анемия, сидероахрестическая анемия, талассемия).\u003Cbr\u003EАнемия, не связанная с дефицитом железа (например, гемолитическая анемия или мегалобластная анемия, вызванная недостатком витамина B12).\u003Cbr\u003EДефицит сахаразы/изомальтазы, непереносимость фруктозы, глюкозо-галактозная мальабсорбция."},{"name":"Способ применения и дозы","value":"Для приема внутрь.\u003Cbr\u003EСуточную дозу можно разделить на несколько приемов или принимать за один раз. Мальтофер следует принимать во время или сразу же после приема пиши.\u003Cbr\u003EМальтофер можно смешивать с фруктовыми и овощными соками, или с детской пищей, или молочной детской смесью, или неалкогольными напитками. Лёгкое окрашивание смеси не оказывает влияния ни на вкус сока/детского питания, ни на эффективность препарата.\u003Cbr\u003EДля точного отмеривания дозы препарата флакон/контейнер (тубу) следует держать вертикально. Капли должны вытекать сразу же. Если этого не происходит, слегка постучите по флакону/контейнеру (тубе) до появления капли. Не встряхивайте флакон/контейнер (тубу).\u003Cbr\u003EЛечение железодефицитной анемии у детей и взрослых\u003Cbr\u003EЛечение до достижения нормального содержания гемоглобина (Hb) занимает приблизительно от 3 до 5 месяцев. После этого лечение следует продолжить в течение 1-2 месяцев в дозе, описанной для случая дефицита железа без анемии, с целью восполнения запасов железа.\u003Cbr\u003EЛечение железодефицитной анемии во время беременности\u003Cbr\u003EЛечение следует продолжать до нормализации содержания гемоглобина (Hb). После этого лечение следует продолжить как минимум до конца беременности в дозе, описанной для случая дефицита железа без анемии, с целью восполнения запасов железа и удовлетворения возросших в связи с беременностью потребностей в железе.\u003Cbr\u003EЛечение и предупреждение дефицита железа без анемии\u003Cbr\u003EЛечение занимает приблизительно от 1 до 2 месяцев."},{"name":"Применение при беременности","value":"Беременность\u003Cbr\u003EДо настоящего времени не поступало сообщений о серьезных нежелательных реакциях после приёма препарата Мальтофер внутрь в терапевтических дозах при лечении анемии во время беременности. Данные, полученные при исследованиях на животных, не показали опасности для плода и матери. Данные клинических исследований о применении препарата Мальтофер в I триместре беременности отсутствуют.\u003Cbr\u003EВ исследованиях, проведенных у беременных женщин после окончания I триместра беременности, не обнаружено никаких нежелательных эффектов препарата Мальтофер в отношении матерей и/или новорожденных. В связи с этим неблагоприятное влияние на плод при применении препарата Мальтофер маловероятно.\u003Cbr\u003EПериод грудного вскармливания\u003Cbr\u003EГрудное молоко женщины содержит железо, связанное с лактоферрином. Количество железа, переходящего из железа (III) гидроксид полимальтозата в грудное молоко, неизвестно. Маловероятно, что применение препарата Мальтофер женщинами, кормящими грудью, способно привести к нежелательным эффектам у ребенка.\u003Cbr\u003EВ качестве меры предосторожности женщинам детородного возраста и женщинам в период беременности и грудного вскармливания следует принимать препарат Мальтофер только после консультации с врачом. Рекомендуется проводить оценку соотношения пользы и риска."},{"name":"Побочные действия","value":"Безопасность и переносимость препарата Мальтофер была оценена во множестве клинических исследований.\u003Cbr\u003EЧастота побочных явлений определялась следующим образом: очень часто (≥1/10), часто (≥1/100, \u003C1/10), нечасто (≥1/1000, \u003C1/100).\u003Cbr\u003EОсновные нежелательные лекарственные реакции, отмеченные в данных исследованиях, имели место в следующих трех классах систем и органов.\u003Cbr\u003EНежелательные лекарственные реакции, наблюдавшиеся в клинических исследованиях\u003Cbr\u003EСо стороны нервной системы: нечасто - головная боль.\u003Cbr\u003EСо стороны пищеварительной системы: очень часто - изменение цвета кала1; часто - диарея, тошнота, диспепсия; нечасто - рвота, запор, боль в животе, изменение цвета эмали зубов2.\u003Cbr\u003EСо стороны кожи и подкожных тканей: нечасто - сыпь, зуд.\u003Cbr\u003E. Часто регистрировали как нежелательное явление (у 23% пациентов), это хорошо известная нежелательная лекарственная реакция на препараты железа для приема внутрь.\u003Cbr\u003E2. Регистрировали как нежелательное явление у 0.6% пациентов, это хорошо известная нежелательная лекарственная реакция на препараты железа для приема внутрь.\u003Cbr\u003E. Включая экзантему.\u003Cbr\u003EСпонтанные постмаркетинговые сообщения о нежелательных лекарственных реакциях\u003Cbr\u003EНе отмечено дополнительных нежелательных лекарственных реакций.\u003Cbr\u003EОтклонения лабораторных показателей\u003Cbr\u003EДанные отсутствуют."},{"name":"Передозировка","value":"В случае передозировки препаратом Мальтофер перегрузка железом или интоксикация маловероятны, что связано с низкой токсичностью железа (III) гидроксид полимальтозата и контролируемым захватом железа. О случаях непреднамеренного отравления с летальным исходом не сообщалось.\u003Cbr\u003EВзаимодействие:\u003Cbr\u003EБыли изучены взаимодействия железа (III) гидроксид полимальтозата с тетрациклином или гидроксидом алюминия. Существенного снижения всасывания тетрациклина не наблюдалось. Концентрация тетрациклина в плазме крови не опускалась ниже эффективного уровня. Всасывание железа из железа (III) гидроксид полимальтозата не снижалось под влиянием алюминия гидроксида или тетрациклина. Таким образом, железа (III) гидроксид полимальтозат можно применять одновременно с тетрациклином и другими фенольными соединениями, а также с гидроксидом алюминия.\u003Cbr\u003EВ исследованиях у крыс с использованием тетрациклина, гидроксида алюминия, ацетилсалициловой кислоты, сульфасалазина, кальция карбоната, кальция ацетата и кальция фосфата в комбинации с витамином D3, бромазепама, магния аспартата, D-пеницилламина, метилдопы, парацетамола и ауранофина не было обнаружено взаимодействий с железа (III) гидроксид полимальтозатом.\u003Cbr\u003EТакже не отмечено взаимодействия железа(III) гидроксид полимальтозата с компонентами продуктов питания, такими, как фитиновая кислота, щавелевая кислота, танин, натрия альгинат, холин и холиновые соли, витамин А, витамин D3 и витамин Е, соевое масло и соевая мука. Данные результаты свидетельствуют о том, что железа (III) гидроксид полимальтозат можно принимать во время или сразу же после приёма пищи.\u003Cbr\u003EПриём препарата не оказывает влияния на результаты определения скрытой крови (с селективным определением гемоглобина), поэтому прерывать лечение не нужно. Необходимо избегать одновременного применения парентеральных и пероральных препаратов железа, поскольку всасывание железа, принимаемого внутрь, замедляется."},{"name":"Условия хранения","value":"При температуре не выше 25°С в защищенном от света месте.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Особые указания","value":"Предполагается, что прием препарата Мальтофер не должен оказывать влияния на суточную потребность в инсулине у пациентов с сахарным диабетом. 1 мл капель содержит 0,01 хлебных единиц.\u003Cbr\u003EАнемия может быть вызвана инфекционными заболеваниями или злокачественными новообразованиями. Поскольку железо можно принимать лишь после устранения основной причины заболевания, следует определить соотношение пользы и риска лечения.\u003Cbr\u003EВо время лечения препаратом Мальтофер может отмечаться тёмное окрашивание кала, однако это не имеет клинического значения.\u003Cbr\u003EМальтофер содержит сахарозу, которая может нанести вред зубам.\u003Cbr\u003EВспомогательные вещества натрия метилпарагидроксибензоат и натрия пропилпарагидроксибензоат могут вызывать аллергические реакции (возможно, замедленного типа)."},{"name":"Страна бренда","value":"Швейцария"},{"name":"Страна производства","value":"Швейцария"},{"name":"Владелец регистрационного удостоверения","value":"Вифор"},{"name":"Изготовитель","value":"Вифор"},{"name":"Фасовщик","value":"Вифор"}]}],"transitionId":"tr_6"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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Структура многоядерного ядра железа (III) гидроксид полимальтозата сходна со структурой ядра белка ферритина - (физиологического депо железа. Железа (III) гидроксид полимальтозат стабилен и в физиологических условиях не выделяет большого количества ионов железа. Из-за размера степень диффузии железа (III) гидроксид полимальтозата через слизистую оболочку приблизительно в 40 раз меньше по сравнению с комплексом шестиводного железа (II). Железо из железа (III) гидроксид полимальтозата активно всасывается в кишечнике.\u003Cbr\u003EЭффективность препарата Мальтофер для нормализации содержания гемоглобина и восполнения депо железа была продемонстрирована в многочисленных рандомизированных контролируемых клинических исследованиях с использованием плацебо-контроля или активного препарата сравнения, проведенных у взрослых и детей с различным статусом депо железа."},{"description":"","filters":[{"id":50921473,"name":"Состав"}],"isMainProperty":false,"name":"Состав","value":"Действующее вещество: железо (в форме комплекса гидроксида железа (III) с полимальтозой) – 2.5 мг\u003Cbr\u003EВспомогательные вещества: сахароза – 50 мг, метилпарагидроксибензоат натрия – 2 мг, пропилпарагидроксибензоат натрия – 0.22 мг, ароматизатор кремовый – 3 мг, натрия гидроксид – до pH 5.5-7.0, вода очищенная – до 1 мл\u003Cbr/\u003E"},{"description":"","filters":[{"id":50921347,"name":"Взаимодействие"}],"isMainProperty":false,"name":"Взаимодействие","value":"Было изучено взаимодействие железа (III) гидроксид полимальтозата с тетрациклином и гидроксидом алюминия. Существенного снижения всасывания тетрациклина не наблюдалось. Концентрация тетрациклина в плазме крови не опускалась ниже эффективного уровня. Всасывание железа из железа (III) гидроксид полимальтозата не снижалось под влиянием алюминия гидроксида или тетрациклина. Таким образом, железа (III) гидроксид полимальтозат можно применять одновременно с тетрациклином и другими фенольными соединениями, а также с гидроксидом алюминия.\u003Cbr\u003EВ исследованиях у крыс с использованием тетрациклина, гидроксида алюминия, ацетилсалициловой кислоты, сульфасалазина, кальция карбоната, кальция ацетата и кальция фосфата в комбинации с витамином D3, бромазепама, магния аспартата, D-пеницилламина, метилдопы, парацетамола и ауранофина не было обнаружено взаимодействия с железа (III) гидроксид полимальтозатом.\u003Cbr\u003EТакже не отмечено взаимодействия железа (III) гидроксид полимальтозата с компонентами продуктов питания, такими, как фитиновая кислота, щавелевая кислота, танин, натрия альгинат, холин и холиновые соли, витамин А, витамин D3 и витамин Е, соевое масло и соевая мука. Данные результаты свидетельствуют о том, что железа (III) гидроксид полимальтозат можно принимать во время или сразу же после приема пищи.\u003Cbr\u003EПрием препарата не оказывает влияния на результаты определения скрытой крови (с селективным определением гемоглобина), поэтому нет необходимости прерывать лечение.\u003Cbr\u003EНеобходимо избегать одновременного применения препаратов железа для парентерального введения и приема внутрь, поскольку всасывание железа, принимаемого внутрь, замедляется."},{"description":"","filters":[{"id":50921465,"name":"Показания к применению"}],"isMainProperty":false,"name":"Показания к применению","value":"Лечение дефицита железа без анемии (латентного дефицита железа) и лечение клинически выраженной железодефицитной анемии (см. раздел \"Способ применения и дозы\").\u003Cbr\u003EПрофилактика дефицита железа во время беременности и в период грудного вскармливания; у женщин детородного возраста, у детей, в подростковом возрасте и у взрослых (например, вегетарианцев и пожилых людей)."},{"description":"","filters":[{"id":50925451,"name":"Противопоказания"}],"isMainProperty":false,"name":"Противопоказания","value":"Установленная гиперчувствительность к железа (III) гидроксид полимальтозату или к любому вспомогательному веществу.\u003Cbr\u003EПерегрузка железом (например, гемосидероз, гемохроматоз).\u003Cbr\u003EНарушение утилизации железа (например, свинцовая анемия, сидероахрестическая анемия, талассемия).\u003Cbr\u003EАнемия, не связанная с дефицитом железа (например, гемолитическая анемия или мегалобластная анемия, вызванная недостатком витамина B12).\u003Cbr\u003EДефицит сахаразы/изомальтазы, непереносимость фруктозы, глюкозо-галактозная мальабсорбция."},{"description":"","filters":[{"id":50921469,"name":"Способ применения и дозы"}],"isMainProperty":false,"name":"Способ применения и дозы","value":"Для приема внутрь.\u003Cbr\u003EСуточную дозу можно разделить на несколько приемов или принимать за один раз. Мальтофер следует принимать во время или сразу же после приема пиши.\u003Cbr\u003EМальтофер можно смешивать с фруктовыми и овощными соками, или с детской пищей, или молочной детской смесью, или неалкогольными напитками. Лёгкое окрашивание смеси не оказывает влияния ни на вкус сока/детского питания, ни на эффективность препарата.\u003Cbr\u003EДля точного отмеривания дозы препарата флакон/контейнер (тубу) следует держать вертикально. Капли должны вытекать сразу же. Если этого не происходит, слегка постучите по флакону/контейнеру (тубе) до появления капли. Не встряхивайте флакон/контейнер (тубу).\u003Cbr\u003EЛечение железодефицитной анемии у детей и взрослых\u003Cbr\u003EЛечение до достижения нормального содержания гемоглобина (Hb) занимает приблизительно от 3 до 5 месяцев. После этого лечение следует продолжить в течение 1-2 месяцев в дозе, описанной для случая дефицита железа без анемии, с целью восполнения запасов железа.\u003Cbr\u003EЛечение железодефицитной анемии во время беременности\u003Cbr\u003EЛечение следует продолжать до нормализации содержания гемоглобина (Hb). После этого лечение следует продолжить как минимум до конца беременности в дозе, описанной для случая дефицита железа без анемии, с целью восполнения запасов железа и удовлетворения возросших в связи с беременностью потребностей в железе.\u003Cbr\u003EЛечение и предупреждение дефицита железа без анемии\u003Cbr\u003EЛечение занимает приблизительно от 1 до 2 месяцев."},{"description":"","filters":[{"id":50921474,"name":"Применение при беременности"}],"isMainProperty":false,"name":"Применение при беременности","value":"Беременность\u003Cbr\u003EДо настоящего времени не поступало сообщений о серьезных нежелательных реакциях после приёма препарата Мальтофер внутрь в терапевтических дозах при лечении анемии во время беременности. Данные, полученные при исследованиях на животных, не показали опасности для плода и матери. Данные клинических исследований о применении препарата Мальтофер в I триместре беременности отсутствуют.\u003Cbr\u003EВ исследованиях, проведенных у беременных женщин после окончания I триместра беременности, не обнаружено никаких нежелательных эффектов препарата Мальтофер в отношении матерей и/или новорожденных. В связи с этим неблагоприятное влияние на плод при применении препарата Мальтофер маловероятно.\u003Cbr\u003EПериод грудного вскармливания\u003Cbr\u003EГрудное молоко женщины содержит железо, связанное с лактоферрином. Количество железа, переходящего из железа (III) гидроксид полимальтозата в грудное молоко, неизвестно. Маловероятно, что применение препарата Мальтофер женщинами, кормящими грудью, способно привести к нежелательным эффектам у ребенка.\u003Cbr\u003EВ качестве меры предосторожности женщинам детородного возраста и женщинам в период беременности и грудного вскармливания следует принимать препарат Мальтофер только после консультации с врачом. Рекомендуется проводить оценку соотношения пользы и риска."},{"description":"","filters":[{"id":50921464,"name":"Побочные действия"}],"isMainProperty":false,"name":"Побочные действия","value":"Безопасность и переносимость препарата Мальтофер была оценена во множестве клинических исследований.\u003Cbr\u003EЧастота побочных явлений определялась следующим образом: очень часто (≥1/10), часто (≥1/100, \u003C1/10), нечасто (≥1/1000, \u003C1/100).\u003Cbr\u003EОсновные нежелательные лекарственные реакции, отмеченные в данных исследованиях, имели место в следующих трех классах систем и органов.\u003Cbr\u003EНежелательные лекарственные реакции, наблюдавшиеся в клинических исследованиях\u003Cbr\u003EСо стороны нервной системы: нечасто - головная боль.\u003Cbr\u003EСо стороны пищеварительной системы: очень часто - изменение цвета кала1; часто - диарея, тошнота, диспепсия; нечасто - рвота, запор, боль в животе, изменение цвета эмали зубов2.\u003Cbr\u003EСо стороны кожи и подкожных тканей: нечасто - сыпь, зуд.\u003Cbr\u003E. Часто регистрировали как нежелательное явление (у 23% пациентов), это хорошо известная нежелательная лекарственная реакция на препараты железа для приема внутрь.\u003Cbr\u003E2. Регистрировали как нежелательное явление у 0.6% пациентов, это хорошо известная нежелательная лекарственная реакция на препараты железа для приема внутрь.\u003Cbr\u003E. Включая экзантему.\u003Cbr\u003EСпонтанные постмаркетинговые сообщения о нежелательных лекарственных реакциях\u003Cbr\u003EНе отмечено дополнительных нежелательных лекарственных реакций.\u003Cbr\u003EОтклонения лабораторных показателей\u003Cbr\u003EДанные отсутствуют."},{"description":"","filters":[{"id":50921468,"name":"Передозировка"}],"isMainProperty":false,"name":"Передозировка","value":"В случае передозировки препаратом Мальтофер перегрузка железом или интоксикация маловероятны, что связано с низкой токсичностью железа (III) гидроксид полимальтозата и контролируемым захватом железа. О случаях непреднамеренного отравления с летальным исходом не сообщалось.\u003Cbr\u003EВзаимодействие:\u003Cbr\u003EБыли изучены взаимодействия железа (III) гидроксид полимальтозата с тетрациклином или гидроксидом алюминия. Существенного снижения всасывания тетрациклина не наблюдалось. Концентрация тетрациклина в плазме крови не опускалась ниже эффективного уровня. Всасывание железа из железа (III) гидроксид полимальтозата не снижалось под влиянием алюминия гидроксида или тетрациклина. Таким образом, железа (III) гидроксид полимальтозат можно применять одновременно с тетрациклином и другими фенольными соединениями, а также с гидроксидом алюминия.\u003Cbr\u003EВ исследованиях у крыс с использованием тетрациклина, гидроксида алюминия, ацетилсалициловой кислоты, сульфасалазина, кальция карбоната, кальция ацетата и кальция фосфата в комбинации с витамином D3, бромазепама, магния аспартата, D-пеницилламина, метилдопы, парацетамола и ауранофина не было обнаружено взаимодействий с железа (III) гидроксид полимальтозатом.\u003Cbr\u003EТакже не отмечено взаимодействия железа(III) гидроксид полимальтозата с компонентами продуктов питания, такими, как фитиновая кислота, щавелевая кислота, танин, натрия альгинат, холин и холиновые соли, витамин А, витамин D3 и витамин Е, соевое масло и соевая мука. Данные результаты свидетельствуют о том, что железа (III) гидроксид полимальтозат можно принимать во время или сразу же после приёма пищи.\u003Cbr\u003EПриём препарата не оказывает влияния на результаты определения скрытой крови (с селективным определением гемоглобина), поэтому прерывать лечение не нужно. Необходимо избегать одновременного применения парентеральных и пероральных препаратов железа, поскольку всасывание железа, принимаемого внутрь, замедляется."},{"description":"","filters":[{"id":50921467,"name":"Условия хранения"}],"isMainProperty":false,"name":"Условия хранения","value":"При температуре не выше 25°С в защищенном от света месте.\u003Cbr\u003EХранить в недоступном для детей месте."},{"description":"","filters":[{"id":50921466,"name":"Особые указания"}],"isMainProperty":false,"name":"Особые указания","value":"Предполагается, что прием препарата Мальтофер не должен оказывать влияния на суточную потребность в инсулине у пациентов с сахарным диабетом. 1 мл капель содержит 0,01 хлебных единиц.\u003Cbr\u003EАнемия может быть вызвана инфекционными заболеваниями или злокачественными новообразованиями. Поскольку железо можно принимать лишь после устранения основной причины заболевания, следует определить соотношение пользы и риска лечения.\u003Cbr\u003EВо время лечения препаратом Мальтофер может отмечаться тёмное окрашивание кала, однако это не имеет клинического значения.\u003Cbr\u003EМальтофер содержит сахарозу, которая может нанести вред зубам.\u003Cbr\u003EВспомогательные вещества натрия метилпарагидроксибензоат и натрия пропилпарагидроксибензоат могут вызывать аллергические реакции (возможно, замедленного типа)."},{"description":"","filters":[{"id":32849454,"name":"Страна бренда"}],"isMainProperty":false,"name":"Страна бренда","value":"Швейцария"},{"description":"","filters":[{"id":16064056,"name":"Страна производства"}],"isMainProperty":false,"name":"Страна производства","value":"Швейцария"},{"description":"","filters":[{"id":34362170,"name":"Владелец регистрационного удостоверения"}],"isMainProperty":false,"name":"Владелец регистрационного 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Ещё может подойти

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Инструкция

Показания к применению

Лечение дефицита железа без анемии (латентного дефицита железа) и лечение клинически выраженной железодефицитной анемии (см. раздел "Способ применения и дозы").
Профилактика дефицита железа во время беременности и в период грудного вскармливания; у женщин детородного возраста, у детей, в подростковом возрасте и у взрослых (например, вегетарианцев и пожилых людей).

Противопоказания

Установленная гиперчувствительность к железа (III) гидроксид полимальтозату или к любому вспомогательному веществу.
Перегрузка железом (например, гемосидероз, гемохроматоз).
Нарушение утилизации железа (например, свинцовая анемия, сидероахрестическая анемия, талассемия).
Анемия, не связанная с дефицитом железа (например, гемолитическая анемия или мегалобластная анемия, вызванная недостатком витамина B12).
Дефицит сахаразы/изомальтазы, непереносимость фруктозы, глюкозо-галактозная мальабсорбция.

Способ применения и дозы

Для приема внутрь.
Суточную дозу можно разделить на несколько приемов или принимать за один раз. Мальтофер следует принимать во время или сразу же после приема пиши.
Мальтофер можно смешивать с фруктовыми и овощными соками, или с детской пищей, или молочной детской смесью, или неалкогольными напитками. Лёгкое окрашивание смеси не оказывает влияния ни на вкус сока/детского питания, ни на эффективность препарата.
Для точного отмеривания дозы препарата флакон/контейнер (тубу) следует держать вертикально. Капли должны вытекать сразу же. Если этого не происходит, слегка постучите по флакону/контейнеру (тубе) до появления капли. Не встряхивайте флакон/контейнер (тубу).
Лечение железодефицитной анемии у детей и взрослых
Лечение до достижения нормального содержания гемоглобина (Hb) занимает приблизительно от 3 до 5 месяцев. После этого лечение следует продолжить в течение 1-2 месяцев в дозе, описанной для случая дефицита железа без анемии, с целью восполнения запасов железа.
Лечение железодефицитной анемии во время беременности
Лечение следует продолжать до нормализации содержания гемоглобина (Hb). После этого лечение следует продолжить как минимум до конца беременности в дозе, описанной для случая дефицита железа без анемии, с целью восполнения запасов железа и удовлетворения возросших в связи с беременностью потребностей в железе.
Лечение и предупреждение дефицита железа без анемии
Лечение занимает приблизительно от 1 до 2 месяцев.
Полная инструкция
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Мальтофер капли д/вн. приема
Мальтофер капли д/вн. приема, 50 мг/мл, 1 шт.
5.0
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3 вопроса
Инструкция
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5.0
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У продавца:31 оценка·2 отзыва
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user avatar
5 месяцев назад • Арина г • Куплен на Маркете
Достоинства: удобно принимать
Недостатки: не выявлено
Комментарий: для меня гораздо приятнее, чем таблетки! знакома с препаратом давно, мягкое действие, моментального результата не ждите, но после курса эффект очень ощутим и сохраняется дольше, чем после таблеток
user avatar
6 месяцев назад • феруза ташбаева • Куплен на Маркете
Комментарий: Эффект заметен сразу
Посмотреть все отзывы на Маркете
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  • Мальтофер фол таб. жев., 30 шт.
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    Мальтофер фол таб. жев., 30 шт.

    Цена 1 323 ₽ вместо 1 336
  • Виагра для мужчин возбудитель быстродействующий таблетки Золотой олень. Средство для потенции эрекции продления секса для двоих
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    Виагра для мужчин возбудитель быстродействующий таблетки Золотой олень. Средство для потенции эрекции продления секса для двоих

    Цена 587 ₽ вместо 1 900
  • Фенибут таб., 250 мг, 20 шт.
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    Фенибут таб., 250 мг, 20 шт.

    Цена 110 ₽
  • ЛимфоТранзит концентрат напитка фл., 100 мл
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    ЛимфоТранзит концентрат напитка фл., 100 мл

    Цена 332 ₽ вместо 390
  • БиоГая Пробиотик капли детск. фл., 5 мл, 1 уп.
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    БиоГая Пробиотик капли детск. фл., 5 мл, 1 уп.

    Цена 2 025 ₽ вместо 3 500
  • Реклама
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  • Сорбифер дурулес таб. п/о, 30 шт.
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    Сорбифер дурулес таб. п/о, 30 шт.

    Цена 702 ₽
  • Тотема р-р д/вн. приема, 20 шт.
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    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:228073257_10/content/content/toggleWishlist":{"skuId":"101295570744","productId":228073257,"offerId":"DgBaQEHfiWVpajpZcbllcw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQuvnEg7TUtO47EhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCKm+4GwQuP6+rfkCGObtwhAgnP6jGA==","sign":"OmikEXicDj6ddc0bHwHdZuM/uBJUnZBLbWogqFMn9IM="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:228073257_10/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Тотема р-р д/вн. приема, 20 шт.

    Цена 708 ₽ вместо 897
  • Силденафил-СЗ таб. п/о плен., 25 мг, 20 шт.
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    Силденафил-СЗ таб. п/о плен., 25 мг, 20 шт.

    Цена 205 ₽ вместо 255
  • Артнео капс., 35 г, 30 шт., нейтральный, 1 уп.
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    Артнео капс., 35 г, 30 шт., нейтральный, 1 уп.

    Цена 1 650 ₽ вместо 4 225
  • Фитоледенцы с подорожником и чабрецом, 90 г, 20 шт., малина, 1 уп.
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    Фитоледенцы с подорожником и чабрецом, 90 г, 20 шт., малина, 1 уп.

    Цена 299 ₽
  • Вигантол р-р д/вн. приема масл., 1 шт.
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    Вигантол р-р д/вн. приема масл., 1 шт.

    Цена 184 ₽
  • Звездочка НОЗ спрей наз. фл. с распылителем, 0.1%, 15 мл
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    Звездочка НОЗ спрей наз. фл. с распылителем, 0.1%, 15 мл

    Цена 92 ₽ вместо 142
  • Левомеколь мазь д/нар. прим., 40 мг/г+7.5 мг/г, 10 г
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    Левомеколь мазь д/нар. прим., 40 мг/г+7.5 мг/г, 10 г

    Цена 184 ₽ вместо 186
  • Феррум лек р-р д/ин., 50 мг/мл, 5 шт.
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    Феррум лек р-р д/ин., 50 мг/мл, 5 шт.

    Цена 1 899 ₽
  • Акридерм крем д/нар. прим., 0.05%, 15 г
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    Акридерм крем д/нар. прим., 0.05%, 15 г

    Цена 92 ₽ вместо 142
  • Капсулы NOW Melatonin, 60 г, 3 мг, 60 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1476624416_19/content/content/gallery":{"title":"Капсулы NOW Melatonin, 60 г, 3 мг, 60 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/4119784/img_id2943673041604507332.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4119784/img_id2943673041604507332.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4119784/img_id2943673041604507332.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4119784/img_id2943673041604507332.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4119784/img_id2943673041604507332.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4119784/img_id2943673041604507332.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/1603927/img_id3010749101966750750.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/1603927/img_id3010749101966750750.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/1603927/img_id3010749101966750750.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/1603927/img_id3010749101966750750.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/1603927/img_id3010749101966750750.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/1603927/img_id3010749101966750750.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/6256254/img_id427841323821731084.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/6256254/img_id427841323821731084.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/6256254/img_id427841323821731084.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/6256254/img_id427841323821731084.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/6256254/img_id427841323821731084.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/6256254/img_id427841323821731084.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQuvnEg7TUtO47EhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIXCKCAjsAFEP+U9Kr8AhjxybYEILr/1Qc=","sign":"tqk0BADdiYkfMPD1DTMCYu0ffLrQsf4UliwaZNTuIeY="},"target":"model_card"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1476624416_19/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
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    Капсулы NOW Melatonin, 60 г, 3 мг, 60 шт.

    Цена 558 ₽ вместо 990
  • Пастилки California Gold Nutrition Vitamin D3 gummies со вкусом фруктов и ягод, 280 г, 90 шт.
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    Пастилки California Gold Nutrition Vitamin D3 gummies со вкусом фруктов и ягод, 280 г, 90 шт.

    Цена 411 ₽ вместо 668
  • Реклама
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  • Тардиферон таб. пролонг. высвоб. п/о плен., 80 мг, 30 шт.
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    Тардиферон таб. пролонг. высвоб. п/о плен., 80 мг, 30 шт.

    Цена 688 ₽
  • Снуп спрей наз., 90 мкг/доза, 15 мл
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    Снуп спрей наз., 90 мкг/доза, 15 мл

    Цена 141 ₽ вместо 191
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