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Описание

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Мексидол р-р для в/в введ. и в/м введ., 50 мг/мл, 2 мл, 10 шт.

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У продавца: 
нет • На Маркете: 4.4
(14)
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Коротко о товаре

Артикул Маркета
3123919220
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
{"widgets":{"@card/SpecsList":{"/content/page/fancyPage/productSpecsList":{"wrapperProps":{"margins":{"top":4,"bottom":4}},"specsLimit":5,"title":"Коротко о товаре","titleSize":"14","type":"minimal","offset":"s","isHealthCategory":true,"forceShowWidget":true,"withFridge":true}}},"meta":{"/content/page/fancyPage/productSpecsList":{"name":"@card/SpecsList"}},"collections":{"minimalSpecs":{"5408926231689081844":{"specItems":[{"name":"Артикул Маркета","value":"3123919220","withCopyValueButton":true},{"name":"тип препарата","value":"рецептурный лекарственный препарат","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["27272850:1,0","34324371:35649313"]}}},{"name":"назначение","value":"дисциркуляторная энцефалопатия, инфаркт миокарда, острые нарушения мозгового кровообращения, синдром вегетативной (нейроциркуляторной) дистонии, тревожные расстройства при невротических и неврозоподобных состояниях","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["36476390:36618697,36618023,36617580,36617542,36617489"]}}},{"name":"действующее вещество","value":"Этилметилгидроксипиридина сукцинат","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["27144131:28710482"]}}},{"name":"возраст","value":"от 18 лет"},{"name":"форма выпуска","value":"раствор для инъекций"},{"name":"страна-производитель","value":"Россия"}]}},"compactSpecs":{"5408926231689081844":{"specItems":[{"name":"Артикул Маркета","value":"3123919220","withCopyValueButton":true},{"name":"Тип препарата","value":"Рецептурный лекарственный препарат","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["27272850:1,0","34324371:35649313"]}}},{"name":"Возраст","value":"От 18 лет"},{"name":"Форма выпуска","value":"Раствор для инъекций"},{"name":"Страна-производитель","value":"Россия"}]}},"fullSpecs":{"5408926231689081844":{"specItems":[{"name":"Тип препарата","value":"лекарственный препарат","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["34324371:35649313"]}}},{"name":"Рецептурный препарат","value":"да","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["27272850:1,0"]}}},{"name":"Органы и системы","value":"нервная система"},{"name":"Назначение","value":"дисциркуляторная энцефалопатия, инфаркт миокарда, острые нарушения мозгового кровообращения, синдром вегетативной (нейроциркуляторной) дистонии, тревожные расстройства при невротических и неврозоподобных состояниях","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["36476390:36618697,36618023,36617580,36617542,36617489"]}}},{"name":"Показания к применению","value":"- Острые нарушения мозгового кровообращения;\u003Cbr /\u003E- черепно-мозговая травма, последствия черепно-мозговых травм;\u003Cbr /\u003E- дисциркуляторная энцефалопатия;\u003Cbr /\u003E- синдром вегетативной дистонии;\u003Cbr /\u003E- легкие когнитивные расстройства атеросклеротического генеза;\u003Cbr /\u003E- тревожные расстройства при невротических и неврозоподобных состояниях;\u003Cbr /\u003E- острый инфаркт миокарда (с первых суток) в составе комплексной терапии;\u003Cbr /\u003E- первичная открытоугольная глаукома различных стадий, в составе комплексной терапии;\u003Cbr /\u003E- купирование абстинентного синдрома при алкоголизме с преобладанием неврозоподобных и вегетативно-сосудистых расстройств;\u003Cbr /\u003E- острая интоксикация антипсихотическими средствами;\u003Cbr /\u003E- острые гнойно-воспалительные процессы брюшной полости (острый некротический панкреатит, перитонит) в составе комплексной терапии."},{"name":"Противопоказания","value":"Острые нарушения функции печени и почек, повышенная индивидуальная чувствительность к препарату. Строго контролируемых клинических исследований безопасности применения препарата Мексидол у детей, при беременности и кормлении грудью не проводилось."},{"name":"Состав","value":"Действующее вещество: этилметилгидроксипиридина сукцинат 50 г;\u003Cbr /\u003Eвспомогательные вещества: натрия метабисульфит 0,4 мг, вода для инъекций до 1 мл."},{"name":"Действующее вещество","value":"Этилметилгидроксипиридина сукцинат","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["27144131:28710482"]}}},{"name":"Способ применения и дозы","value":"В/м или в/в (струйно или капельно). При инфузионном способе введения препарат следует разводить в 0,9% растворе натрия хлорида.\u003Cbr /\u003EСтруйно Мексидол вводят медленно в течение 5-7 мин, капельно - со скоростью 40-60 капель в минуту. Максимальная суточная доза не должна превышать 1200 мг.\u003Cbr /\u003EПри острых нарушениях мозгового кровообращения Мексидол применяют в первые 10-14 дней - в/в капельно по 200-500 мг 2-4 раза в сутки, затем в/м по 200-250 мг 2-3 раза в сутки в течение 2 недель.\u003Cbr /\u003EПри черепно-мозговой травме и последствиях черепно-мозговых травм Мексидол применяют в течении 10-15 дней в/в капельно по 200-500 мг 2-4 раза в сутки.\u003Cbr /\u003EПри дисциркуляторной энцефалопатии в фазе декомпенсации Мексидол следует назначать в/в струйно или капельно в дозе 200-500 мг 1- 2 раза в сутки на протяжении 14 дней. Затем в/м по 100-250 мг/сут. на протяжении последующих 2 нед.\u003Cbr /\u003EДля курсовой профилактики дисциркуляторной энцефалопатии препарат вводят в/м в дозе 200-250 мг 2 раза в сутки на протяжении 10-14 дней.\u003Cbr /\u003EПри легких когнитивных нарушениях у больных пожилого возраста и при тревожных расстройствах препарат применяют в/м в суточной дозе 100-300 мг/сут на протяжении 14-30 дней.\u003Cbr /\u003EПри остром инфаркте миокарда в составе комплексной терапии Мексидол вводят внутривенно или внутримышечно в течение 14 суток, на фоне традиционной терапии инфаркта миокарда, включающей нитраты, бета-адреноблокаторы, ингибиторы ангиотензинпревращающего фермента (АПФ), тромболитики, антикоагулянтные и антиагрегантные средства, а также симптоматические средства по показаниям.\u003Cbr /\u003EВ первые 5 суток для достижения максимального эффекта препарат желательно вводить внутривенно, в последующие 9 суток Мексидол может вводиться внутримышечно. Внутривенное введение препарата производят путем капельной инфузии, медленно (во избежание побочных эффектов) на 0,9% растворе натрия хлорида или 5% растворе декстрозы (глюкозы) в объеме 100-150 мл в течение 30-90 мин. При необходимости возможно медленное струйное введение препарата, продолжительностью не менее 5 минут.\u003Cbr /\u003EВведение препарата (внутривенное или внутримышечное) осуществляют 3 раза в сутки, через каждые 8 часов. Суточная терапевтическая доза составляет 6-9 мг/кг массы тела в сутки, разовая доза - 2-3 мг/кг массы тела. Максимальная суточная доза не должна превышать 800 мг, разовая - 250 мг.\u003Cbr /\u003EПри открытоугольной глаукоме различных стадий в составе комплексной терапии Мексидол вводят внутримышечно по 100-300 мг/сутки, 1-3 раза в сутки в течение 14 дней.\u003Cbr /\u003EПри абстинентном алкогольном синдроме Мексидол вводят в дозе 200-500 мг в/в капельно или в/м 2-3 раза в сутки в сутки в течение 5-7 дней.\u003Cbr /\u003EПри острой интоксикации антипсихотическими средствами препарат вводят в/в в дозе 200-500 мг/сут на протяжении 7-14 дней.\u003Cbr /\u003EПри острых гнойно-воспалительных процессах брюшной полости (острый некротический панкреатит, перитонит) препарат назначают в первые сутки как в предоперационном, так и в послеоперационном периоде. Вводимые дозы зависят от формы и тяжести заболевания, распространенности процесса, вариантов клинического течения. Отмена препарата должна производиться постепенно только после устойчивого положительного клинико-лабораторного эффекта.\u003Cbr /\u003EПри остром отечном (интерстициальном) панкреатите Мексидол назначают по 200-500 мг 3 раза в день, в/в капельно (в 0,9% растворе натрия хлорида) и в/м.\u003Cbr /\u003EЛегкая степень тяжести некротического панкреатита - по 100-200 мг 3 раза в день в/в капельно (в 0,9% растворе натрия хлорида) и в/м.\u003Cbr /\u003EСредняя степень тяжести - по 200 мг 3 раза в день, в/в капельно (в 0,9% растворе натрия хлорида).\u003Cbr /\u003EТяжелое течение - в пульс- дозировке 800 мг в первые сутки, при двукратном режиме введения; далее по 200-500 мг 2 раза в день с постепенным снижением суточной дозы.\u003Cbr /\u003EКрайне тяжелое течение - в начальной дозировке 800 мг/сут до стойкого купирования проявлений панкреатогенного шока, по стабилизации состояния по 300-500 мг 2 раза в день в/в капельно (в 0,9% растворе натрия хлорида) с постепенным снижением суточной дозировки."},{"name":"Побочные действия","value":"Возможно появление тошноты и сухости слизистой рта, сонливости, аллергических реакций."},{"name":"Фармакологическое действие","value":"Оказывает антигипоксическое, мембранопротекторное, ноотропное, противосудорожное, анксиолитическое действие, повышает устойчивость организма к стрессу. Препарат повышает резистентность организма к воздействию основных повреждающих факторов, к кислородзависимым патологическим состояниям (шок, гипоксия и ишемия, нарушение мозгового кровообращения, интоксикация алкоголем и антипсихотическими препаратами (нейролептиками)).\u003Cbr /\u003EМексидол улучшает мозговой метаболизм и кровоснабжение головного мозга, улучшает микроциркуляцию и реологические свойства крови, уменьшает агрегацию тромбоцитов. Стабилизирует мембранные структуры клеток крови (эритроциты и тромбоциты) при гемолизе. Оказывает гиполипидемическое действие, уменьшает уровень общего холестерина и ЛПНП.\u003Cbr /\u003EУменьшает ферментативную токсемию и эндогенную интоксикацию при остром панкреатите.\u003Cbr /\u003EМеханизм действия Мексидола обусловлен его антигипоксантным, антиоксидантным и мембранопротекторным действием. Он ингибирует процессы перекисного окисления липидов, повышает активность супероксиддисмутазы, повышает соотношение липид-белок, уменьшает вязкость мембраны, увеличивает ее текучесть. Модулирует активность мембраносвязанных ферментов (кальцийнезависимая фосфодиэстераза, аденилатциклаза, ацетилхолинэстераза), рецепторных комплексов (бензодиазепиновый, ГАМК, ацетилхолиновый), что усиливает их способность связывания с лигандами, помогает сохранению структурно-функциональной организации биомембран, транспорта нейромедиаторов и улучшению синаптической передачи. Мексидол повышает содержание дофамина в головном мозге. Вызывает усиление компенсаторной активности аэробного гликолиза и снижение степени угнетения окислительных процессов в цикле Кребса в условиях гипоксии, с увеличением содержания АТФ, креатинфосфата и активацией энергосинтезирующих функций митохондрий, стабилизацию клеточных мембран. Мексидол нормализует метаболические процессы в ишемизированном миокарде, уменьшает зону некроза, восстанавливает и улучшает электрическую активность и сократимость миокарда, а также увеличивает коронарный кровоток в зоне ишемии, уменьшает последствия реперфузионного синдрома при острой коронарной недостаточности. Повышает антиангинальную активность нитропрепаратов. Мексидол способствует сохранению ганглиозных клеток сетчатки и волокон зрительного нерва при прогрессирующей нейропатии, причинами которой являются хроническая ишемия и гипоксия. Улучшает функциональную активность сетчатки и зрительного нерва, увеличивая остроту зрения."},{"name":"Фармакологическая группа","value":"препараты для лечения заболеваний нервной системы прочие"},{"name":"Форма выпуска","value":"раствор для инъекций"},{"name":"Способ применения/введения","value":"парентеральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["35947170:36763748"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"Хранить в сухом защищённом от света недоступном для детей месте при температуре не выше 25°С."},{"name":"Передозировка","value":"При передозировке возможно развитие сонливости."},{"name":"Применение при беременности и кормлении грудью","value":"Противопоказано."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В период приема препарата следует соблюдать осторожность при работе, требующей быстроты психофизических реакций (управление транспортными средствами, механизмами и т.п.)."},{"name":"Особые указания","value":"В отдельных случаях, особенно у предрасположенных пациентов с бронхиальной астмой при повышенной чувствительности к сульфитам, возможно развитие тяжелых реакций гиперчувствительности."},{"name":"Взаимодействие","value":"Усиливает действие бензодиазепиновых анксиолитиков, противосудорожных средств (карбамазепина), противопаркинсонических средств (леводопа).\u003Cbr /\u003EУменьшает токсические эффекты этилового спирта."},{"name":"Регистрационный номер","value":"Р N002161/01"},{"name":"Дата государственной регистрации","value":"13.01.2020"},{"name":"Владелец регистрационного удостоверения","value":"Фармасофт","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["34324371:35649313","7893318:12531373"]}}},{"name":"Изготовитель","value":"Московский эндокринный завод"},{"name":"Фасовщик","value":"Московский эндокринный завод"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Мексидол","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["17796364:18007914"]}}},{"name":"Срок годности","value":"36 мес."}]}},"fullSpecsGrouped":{"5408926231689081844":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"нервная система"},{"name":"Назначение","value":"дисциркуляторная энцефалопатия, инфаркт миокарда, острые нарушения мозгового кровообращения, синдром вегетативной (нейроциркуляторной) дистонии, тревожные расстройства при невротических и неврозоподобных состояниях"},{"name":"Показания к применению","value":"- Острые нарушения мозгового кровообращения;\u003Cbr /\u003E- черепно-мозговая травма, последствия черепно-мозговых травм;\u003Cbr /\u003E- дисциркуляторная энцефалопатия;\u003Cbr /\u003E- синдром вегетативной дистонии;\u003Cbr /\u003E- легкие когнитивные расстройства атеросклеротического генеза;\u003Cbr /\u003E- тревожные расстройства при невротических и неврозоподобных состояниях;\u003Cbr /\u003E- острый инфаркт миокарда (с первых суток) в составе комплексной терапии;\u003Cbr /\u003E- первичная открытоугольная глаукома различных стадий, в составе комплексной терапии;\u003Cbr /\u003E- купирование абстинентного синдрома при алкоголизме с преобладанием неврозоподобных и вегетативно-сосудистых расстройств;\u003Cbr /\u003E- острая интоксикация антипсихотическими средствами;\u003Cbr /\u003E- острые гнойно-воспалительные процессы брюшной полости (острый некротический панкреатит, перитонит) в составе комплексной терапии."},{"name":"Противопоказания","value":"Острые нарушения функции печени и почек, повышенная индивидуальная чувствительность к препарату. Строго контролируемых клинических исследований безопасности применения препарата Мексидол у детей, при беременности и кормлении грудью не проводилось."},{"name":"Состав","value":"Действующее вещество: этилметилгидроксипиридина сукцинат 50 г;\u003Cbr /\u003Eвспомогательные вещества: натрия метабисульфит 0,4 мг, вода для инъекций до 1 мл."},{"name":"Действующее вещество","value":"Этилметилгидроксипиридина сукцинат"},{"name":"Способ применения и дозы","value":"В/м или в/в (струйно или капельно). При инфузионном способе введения препарат следует разводить в 0,9% растворе натрия хлорида.\u003Cbr /\u003EСтруйно Мексидол вводят медленно в течение 5-7 мин, капельно - со скоростью 40-60 капель в минуту. Максимальная суточная доза не должна превышать 1200 мг.\u003Cbr /\u003EПри острых нарушениях мозгового кровообращения Мексидол применяют в первые 10-14 дней - в/в капельно по 200-500 мг 2-4 раза в сутки, затем в/м по 200-250 мг 2-3 раза в сутки в течение 2 недель.\u003Cbr /\u003EПри черепно-мозговой травме и последствиях черепно-мозговых травм Мексидол применяют в течении 10-15 дней в/в капельно по 200-500 мг 2-4 раза в сутки.\u003Cbr /\u003EПри дисциркуляторной энцефалопатии в фазе декомпенсации Мексидол следует назначать в/в струйно или капельно в дозе 200-500 мг 1- 2 раза в сутки на протяжении 14 дней. Затем в/м по 100-250 мг/сут. на протяжении последующих 2 нед.\u003Cbr /\u003EДля курсовой профилактики дисциркуляторной энцефалопатии препарат вводят в/м в дозе 200-250 мг 2 раза в сутки на протяжении 10-14 дней.\u003Cbr /\u003EПри легких когнитивных нарушениях у больных пожилого возраста и при тревожных расстройствах препарат применяют в/м в суточной дозе 100-300 мг/сут на протяжении 14-30 дней.\u003Cbr /\u003EПри остром инфаркте миокарда в составе комплексной терапии Мексидол вводят внутривенно или внутримышечно в течение 14 суток, на фоне традиционной терапии инфаркта миокарда, включающей нитраты, бета-адреноблокаторы, ингибиторы ангиотензинпревращающего фермента (АПФ), тромболитики, антикоагулянтные и антиагрегантные средства, а также симптоматические средства по показаниям.\u003Cbr /\u003EВ первые 5 суток для достижения максимального эффекта препарат желательно вводить внутривенно, в последующие 9 суток Мексидол может вводиться внутримышечно. Внутривенное введение препарата производят путем капельной инфузии, медленно (во избежание побочных эффектов) на 0,9% растворе натрия хлорида или 5% растворе декстрозы (глюкозы) в объеме 100-150 мл в течение 30-90 мин. При необходимости возможно медленное струйное введение препарата, продолжительностью не менее 5 минут.\u003Cbr /\u003EВведение препарата (внутривенное или внутримышечное) осуществляют 3 раза в сутки, через каждые 8 часов. Суточная терапевтическая доза составляет 6-9 мг/кг массы тела в сутки, разовая доза - 2-3 мг/кг массы тела. Максимальная суточная доза не должна превышать 800 мг, разовая - 250 мг.\u003Cbr /\u003EПри открытоугольной глаукоме различных стадий в составе комплексной терапии Мексидол вводят внутримышечно по 100-300 мг/сутки, 1-3 раза в сутки в течение 14 дней.\u003Cbr /\u003EПри абстинентном алкогольном синдроме Мексидол вводят в дозе 200-500 мг в/в капельно или в/м 2-3 раза в сутки в сутки в течение 5-7 дней.\u003Cbr /\u003EПри острой интоксикации антипсихотическими средствами препарат вводят в/в в дозе 200-500 мг/сут на протяжении 7-14 дней.\u003Cbr /\u003EПри острых гнойно-воспалительных процессах брюшной полости (острый некротический панкреатит, перитонит) препарат назначают в первые сутки как в предоперационном, так и в послеоперационном периоде. Вводимые дозы зависят от формы и тяжести заболевания, распространенности процесса, вариантов клинического течения. Отмена препарата должна производиться постепенно только после устойчивого положительного клинико-лабораторного эффекта.\u003Cbr /\u003EПри остром отечном (интерстициальном) панкреатите Мексидол назначают по 200-500 мг 3 раза в день, в/в капельно (в 0,9% растворе натрия хлорида) и в/м.\u003Cbr /\u003EЛегкая степень тяжести некротического панкреатита - по 100-200 мг 3 раза в день в/в капельно (в 0,9% растворе натрия хлорида) и в/м.\u003Cbr /\u003EСредняя степень тяжести - по 200 мг 3 раза в день, в/в капельно (в 0,9% растворе натрия хлорида).\u003Cbr /\u003EТяжелое течение - в пульс- дозировке 800 мг в первые сутки, при двукратном режиме введения; далее по 200-500 мг 2 раза в день с постепенным снижением суточной дозы.\u003Cbr /\u003EКрайне тяжелое течение - в начальной дозировке 800 мг/сут до стойкого купирования проявлений панкреатогенного шока, по стабилизации состояния по 300-500 мг 2 раза в день в/в капельно (в 0,9% растворе натрия хлорида) с постепенным снижением суточной дозировки."},{"name":"Побочные действия","value":"Возможно появление тошноты и сухости слизистой рта, сонливости, аллергических реакций."},{"name":"Фармакологическое действие","value":"Оказывает антигипоксическое, мембранопротекторное, ноотропное, противосудорожное, анксиолитическое действие, повышает устойчивость организма к стрессу. Препарат повышает резистентность организма к воздействию основных повреждающих факторов, к кислородзависимым патологическим состояниям (шок, гипоксия и ишемия, нарушение мозгового кровообращения, интоксикация алкоголем и антипсихотическими препаратами (нейролептиками)).\u003Cbr /\u003EМексидол улучшает мозговой метаболизм и кровоснабжение головного мозга, улучшает микроциркуляцию и реологические свойства крови, уменьшает агрегацию тромбоцитов. Стабилизирует мембранные структуры клеток крови (эритроциты и тромбоциты) при гемолизе. Оказывает гиполипидемическое действие, уменьшает уровень общего холестерина и ЛПНП.\u003Cbr /\u003EУменьшает ферментативную токсемию и эндогенную интоксикацию при остром панкреатите.\u003Cbr /\u003EМеханизм действия Мексидола обусловлен его антигипоксантным, антиоксидантным и мембранопротекторным действием. Он ингибирует процессы перекисного окисления липидов, повышает активность супероксиддисмутазы, повышает соотношение липид-белок, уменьшает вязкость мембраны, увеличивает ее текучесть. Модулирует активность мембраносвязанных ферментов (кальцийнезависимая фосфодиэстераза, аденилатциклаза, ацетилхолинэстераза), рецепторных комплексов (бензодиазепиновый, ГАМК, ацетилхолиновый), что усиливает их способность связывания с лигандами, помогает сохранению структурно-функциональной организации биомембран, транспорта нейромедиаторов и улучшению синаптической передачи. Мексидол повышает содержание дофамина в головном мозге. Вызывает усиление компенсаторной активности аэробного гликолиза и снижение степени угнетения окислительных процессов в цикле Кребса в условиях гипоксии, с увеличением содержания АТФ, креатинфосфата и активацией энергосинтезирующих функций митохондрий, стабилизацию клеточных мембран. Мексидол нормализует метаболические процессы в ишемизированном миокарде, уменьшает зону некроза, восстанавливает и улучшает электрическую активность и сократимость миокарда, а также увеличивает коронарный кровоток в зоне ишемии, уменьшает последствия реперфузионного синдрома при острой коронарной недостаточности. Повышает антиангинальную активность нитропрепаратов. Мексидол способствует сохранению ганглиозных клеток сетчатки и волокон зрительного нерва при прогрессирующей нейропатии, причинами которой являются хроническая ишемия и гипоксия. Улучшает функциональную активность сетчатки и зрительного нерва, увеличивая остроту зрения."},{"name":"Фармакологическая группа","value":"препараты для лечения заболеваний нервной системы прочие"},{"name":"Форма выпуска","value":"раствор для инъекций"},{"name":"Способ применения/введения","value":"парентеральный"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"Хранить в сухом защищённом от света недоступном для детей месте при температуре не выше 25°С."},{"name":"Передозировка","value":"При передозировке возможно развитие сонливости."},{"name":"Применение при беременности и кормлении грудью","value":"Противопоказано."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В период приема препарата следует соблюдать осторожность при работе, требующей быстроты психофизических реакций (управление транспортными средствами, механизмами и т.п.)."},{"name":"Особые указания","value":"В отдельных случаях, особенно у предрасположенных пациентов с бронхиальной астмой при повышенной чувствительности к сульфитам, возможно развитие тяжелых реакций гиперчувствительности."},{"name":"Взаимодействие","value":"Усиливает действие бензодиазепиновых анксиолитиков, противосудорожных средств (карбамазепина), противопаркинсонических средств (леводопа).\u003Cbr /\u003EУменьшает токсические эффекты этилового спирта."},{"name":"Регистрационный номер","value":"Р N002161/01"},{"name":"Дата государственной регистрации","value":"13.01.2020"},{"name":"Владелец регистрационного удостоверения","value":"Фармасофт"},{"name":"Изготовитель","value":"Московский эндокринный завод"},{"name":"Фасовщик","value":"Московский эндокринный завод"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Мексидол"},{"name":"Срок годности","value":"36 мес."}]}],"transitionId":"tr_18070986279259522411"}}}}
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    на основе 58 оценок
    Цена 508 ₽
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  • Мексидол р-р для в/в и в/м введ. амп., 50 мг/мл, 5 мл, 10 шт.
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    Мексидол р-р для в/в и в/м введ. амп., 50 мг/мл, 5 мл, 10 шт.

    Рейтинг товара: 4.8 из 5
    на основе 45 оценок
    Цена 920 ₽
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  • Мексидол таб. п/о плен., 125 мг, 30 шт.
    –17 %
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    Мексидол таб. п/о плен., 125 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 62 оценки
    Цена 293 ₽ вместо 355
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  • Нейромексол р-р для в/в и в/м введ., 50 мг/мл, 2 мл, 10 шт.
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    Нейромексол р-р для в/в и в/м введ., 50 мг/мл, 2 мл, 10 шт.

    Рейтинг товара: 3 из 5
    на основе 2 оценки
    Цена 320 ₽
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  • Мексифин р-р для в/в введ. и в/м введ., 50 мг/мл, 2 мл, 10 шт.
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    Мексифин р-р для в/в введ. и в/м введ., 50 мг/мл, 2 мл, 10 шт.

    Рейтинг товара: 3.4 из 5
    на основе 8 оценок
    Цена 315 ₽
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  • Мексидол форте таб. п/о. плен., 250 мг, 40 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-2mo67g40ghi/toggleWishlist":{"skuId":"636307077","productId":1778173011,"offerId":"pZ0WUIreTjwanf5kc4SSOw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgsQm6/AjbePt4SIARIxCi9Db21wZXRpdGl2ZUFuYWxvZ3NfTWFya2V0TW9kZWxDYXJkX0Zyb250U25pcHBldDIWCNOI888GEIWNta8CGK3t/AUg7dnBBw==","sign":"o/+/X1pqmAoHtfi8KbIPaY5F88uPKUKMbV/Fwills8I="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-2mo67g40ghi/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Мексидол форте таб. п/о. плен., 250 мг, 40 шт.

    Рейтинг товара: 4.8 из 5
    на основе 70 оценок
    Цена 717 ₽
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  • Конвулекс р-р для в/в введ. введ. амп., 100 мг/мл, 5 мл, 5 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-mo57yekt7l/toggleWishlist":{"skuId":"655023003","productId":1778173035,"offerId":"Rzzk3f_HGbK68049-Rt54Q","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgsQm6/AjbePt4SIARIxCi9Db21wZXRpdGl2ZUFuYWxvZ3NfTWFya2V0TW9kZWxDYXJkX0Zyb250U25pcHBldDIWCOuI888GEJu3q7gCGLrUiREg7dnBBw==","sign":"ixP+rWZhvjFlMWgoYWNx7dLWHe+zaVItAiR4Cj6mXz8="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-mo57yekt7l/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Конвулекс р-р для в/в введ. введ. амп., 100 мг/мл, 5 мл, 5 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 1 154 ₽
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  • Амитриптилин р-р для в/в и в/м введ. амп., 10 мг/мл, 2 мл, 10 шт.
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    Амитриптилин р-р для в/в и в/м введ. амп., 10 мг/мл, 2 мл, 10 шт.

    Рейтинг товара: 4.5 из 5
    на основе 26 оценок
    Цена 121 ₽
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  • Мексидол форте таб. п/о. плен., 250 мг, 40 шт., 1 уп.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-zpctkd9gkpi/toggleWishlist":{"skuId":"102679923386","productId":52482647,"offerId":"BBgA-by-raffkogxX0ROVg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgsQm6/AjbePt4SIARIxCi9Db21wZXRpdGl2ZUFuYWxvZ3NfTWFya2V0TW9kZWxDYXJkX0Zyb250U25pcHBldDIWCNekgxkQupXNwf4CGK3t/AUg7dnBBw==","sign":"LaSgXkhZ2ndEjMghg8F/UwMPhjYohG/CAGgXhfCvd3Q="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-zpctkd9gkpi/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Мексидол форте таб. п/о. плен., 250 мг, 40 шт., 1 уп.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 792 ₽
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  • Церепро р-р для в/в введ. и в/м введ. амп., 250 мг/мл, 4 мл, 5 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-5odt66lphf8/toggleWishlist":{"skuId":"186858063","productId":1404748463,"offerId":"ZMk0qrVFfcvt_APoQNJzmw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgsQm6/AjbePt4SIARIxCi9Db21wZXRpdGl2ZUFuYWxvZ3NfTWFya2V0TW9kZWxDYXJkX0Zyb250U25pcHBldDIVCK+F650FEM/0jFkY2tShBSDt2cEH","sign":"WFc2sC2cF9XQYEjObjNS3trJIXSoUQB9YfOLGiWpwBk="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-5odt66lphf8/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Церепро р-р для в/в введ. и в/м введ. амп., 250 мг/мл, 4 мл, 5 шт.

    Рейтинг товара: 4.6 из 5
    на основе 30 оценок
    Цена 705 ₽
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  • Энцетрон-СОЛОфарм р-р для в/в и в/м введ. амп., 125 мг/мл, 4 мл, 5 шт.
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    Энцетрон-СОЛОфарм р-р для в/в и в/м введ. амп., 125 мг/мл, 4 мл, 5 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 252 ₽
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  • Армадин 50 р-р для в/в и в/м введ., 50 мг/мл, 5 мл, 0.5 г, 5 шт.
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    Армадин 50 р-р для в/в и в/м введ., 50 мг/мл, 5 мл, 0.5 г, 5 шт.

    Рейтинг товара: 3 из 5
    на основе 2 оценки
    Цена 446 ₽
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Инструкция

Показания к применению

- Острые нарушения мозгового кровообращения;
- черепно-мозговая травма, последствия черепно-мозговых травм;
- дисциркуляторная энцефалопатия;
- синдром вегетативной дистонии;
- легкие когнитивные расстройства атеросклеротического генеза;
- тревожные расстройства при невротических и неврозоподобных состояниях;
- острый инфаркт миокарда (с первых суток) в составе комплексной терапии;
- первичная открытоугольная глаукома различных стадий, в составе комплексной терапии;
- купирование абстинентного синдрома при алкоголизме с преобладанием неврозоподобных и вегетативно-сосудистых расстройств;
- острая интоксикация антипсихотическими средствами;
- острые гнойно-воспалительные процессы брюшной полости (острый некротический панкреатит, перитонит) в составе комплексной терапии.

Противопоказания

Острые нарушения функции печени и почек, повышенная индивидуальная чувствительность к препарату. Строго контролируемых клинических исследований безопасности применения препарата Мексидол у детей, при беременности и кормлении грудью не проводилось.

Способ применения и дозы

В/м или в/в (струйно или капельно). При инфузионном способе введения препарат следует разводить в 0,9% растворе натрия хлорида.
Струйно Мексидол вводят медленно в течение 5-7 мин, капельно - со скоростью 40-60 капель в минуту. Максимальная суточная доза не должна превышать 1200 мг.
При острых нарушениях мозгового кровообращения Мексидол применяют в первые 10-14 дней - в/в капельно по 200-500 мг 2-4 раза в сутки, затем в/м по 200-250 мг 2-3 раза в сутки в течение 2 недель.
При черепно-мозговой травме и последствиях черепно-мозговых травм Мексидол применяют в течении 10-15 дней в/в капельно по 200-500 мг 2-4 раза в сутки.
При дисциркуляторной энцефалопатии в фазе декомпенсации Мексидол следует назначать в/в струйно или капельно в дозе 200-500 мг 1- 2 раза в сутки на протяжении 14 дней. Затем в/м по 100-250 мг/сут. на протяжении последующих 2 нед.
Для курсовой профилактики дисциркуляторной энцефалопатии препарат вводят в/м в дозе 200-250 мг 2 раза в сутки на протяжении 10-14 дней.
При легких когнитивных нарушениях у больных пожилого возраста и при тревожных расстройствах препарат применяют в/м в суточной дозе 100-300 мг/сут на протяжении 14-30 дней.
При остром инфаркте миокарда в составе комплексной терапии Мексидол вводят внутривенно или внутримышечно в течение 14 суток, на фоне традиционной терапии инфаркта миокарда, включающей нитраты, бета-адреноблокаторы, ингибиторы ангиотензинпревращающего фермента (АПФ), тромболитики, антикоагулянтные и антиагрегантные средства, а также симптоматические средства по показаниям.
В первые 5 суток для достижения максимального эффекта препарат желательно вводить внутривенно, в последующие 9 суток Мексидол может вводиться внутримышечно. Внутривенное введение препарата производят путем капельной инфузии, медленно (во избежание побочных эффектов) на 0,9% растворе натрия хлорида или 5% растворе декстрозы (глюкозы) в объеме 100-150 мл в течение 30-90 мин. При необходимости возможно медленное струйное введение препарата, продолжительностью не менее 5 минут.
Введение препарата (внутривенное или внутримышечное) осуществляют 3 раза в сутки, через каждые 8 часов. Суточная терапевтическая доза составляет 6-9 мг/кг массы тела в сутки, разовая доза - 2-3 мг/кг массы тела. Максимальная суточная доза не должна превышать 800 мг, разовая - 250 мг.
При открытоугольной глаукоме различных стадий в составе комплексной терапии Мексидол вводят внутримышечно по 100-300 мг/сутки, 1-3 раза в сутки в течение 14 дней.
При абстинентном алкогольном синдроме Мексидол вводят в дозе 200-500 мг в/в капельно или в/м 2-3 раза в сутки в сутки в течение 5-7 дней.
При острой интоксикации антипсихотическими средствами препарат вводят в/в в дозе 200-500 мг/сут на протяжении 7-14 дней.
При острых гнойно-воспалительных процессах брюшной полости (острый некротический панкреатит, перитонит) препарат назначают в первые сутки как в предоперационном, так и в послеоперационном периоде. Вводимые дозы зависят от формы и тяжести заболевания, распространенности процесса, вариантов клинического течения. Отмена препарата должна производиться постепенно только после устойчивого положительного клинико-лабораторного эффекта.
При остром отечном (интерстициальном) панкреатите Мексидол назначают по 200-500 мг 3 раза в день, в/в капельно (в 0,9% растворе натрия хлорида) и в/м.
Легкая степень тяжести некротического панкреатита - по 100-200 мг 3 раза в день в/в капельно (в 0,9% растворе натрия хлорида) и в/м.
Средняя степень тяжести - по 200 мг 3 раза в день, в/в капельно (в 0,9% растворе натрия хлорида).
Тяжелое течение - в пульс- дозировке 800 мг в первые сутки, при двукратном режиме введения; далее по 200-500 мг 2 раза в день с постепенным снижением суточной дозы.
Крайне тяжелое течение - в начальной дозировке 800 мг/сут до стойкого купирования проявлений панкреатогенного шока, по стабилизации состояния по 300-500 мг 2 раза в день в/в капельно (в 0,9% растворе натрия хлорида) с постепенным снижением суточной дозировки.
Полная инструкция
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Мексидол р-р для в/в введ. и в/м введ.
Мексидол р-р для в/в введ. и в/м введ., 50 мг/мл, 2 мл, 10 шт.
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    Цена 920 ₽
  • Мексидол таб. п/о плен., 125 мг, 30 шт.
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    Мексидол таб. п/о плен., 125 мг, 30 шт.

    Цена 293 ₽ вместо 355
  • Нейромексол р-р для в/в и в/м введ., 50 мг/мл, 2 мл, 10 шт.
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    Нейромексол р-р для в/в и в/м введ., 50 мг/мл, 2 мл, 10 шт.

    Цена 320 ₽
  • Мексифин р-р для в/в введ. и в/м введ., 50 мг/мл, 2 мл, 10 шт.
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    Мексифин р-р для в/в введ. и в/м введ., 50 мг/мл, 2 мл, 10 шт.

    Цена 315 ₽
  • Мексидол форте таб. п/о. плен., 250 мг, 40 шт.
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    Мексидол форте таб. п/о. плен., 250 мг, 40 шт.

    Цена 717 ₽
  • Конвулекс р-р для в/в введ. введ. амп., 100 мг/мл, 5 мл, 5 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778173035_6/content/content/toggleWishlist":{"skuId":"655023003","productId":1778173035,"offerId":"Rzzk3f_HGbK68049-Rt54Q","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgsQm6/AjbePt4SIARIaChhyZW1peF9kZXNrdG9wX21vZGVsX2NhcmQyFgjriPPPBhCbt6u4Ahi61IkRIO3ZwQc=","sign":"lbirXu/867kN4Ph0OTxmM8nJir5EnYd+eSkO0JIwxhw="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778173035_6/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Конвулекс р-р для в/в введ. введ. амп., 100 мг/мл, 5 мл, 5 шт.

    Цена 1 154 ₽
  • Амитриптилин р-р для в/в и в/м введ. амп., 10 мг/мл, 2 мл, 10 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778172715_7/content/content/gallery":{"title":"Амитриптилин р-р для в/в и в/м введ. амп., 10 мг/мл, 2 мл, 10 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/5232651/img_id3421908669509865043.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5232651/img_id3421908669509865043.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5232651/img_id3421908669509865043.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5232651/img_id3421908669509865043.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5232651/img_id3421908669509865043.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5232651/img_id3421908669509865043.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/5254781/img_id4857608041315913911.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5254781/img_id4857608041315913911.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5254781/img_id4857608041315913911.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5254781/img_id4857608041315913911.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5254781/img_id4857608041315913911.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5254781/img_id4857608041315913911.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4732637/img_id5746675071301124151.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4732637/img_id5746675071301124151.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4732637/img_id5746675071301124151.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4732637/img_id5746675071301124151.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4732637/img_id5746675071301124151.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4732637/img_id5746675071301124151.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgsQm6/AjbePt4SIARIaChhyZW1peF9kZXNrdG9wX21vZGVsX2NhcmQyFQirhvPPBhCpodxsGMrc0Acg7dnBBw==","sign":"ip4uLPu9IrcLnfwRm7F7obHtnW3sZeoft26uY26qk+k="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778172715_7/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
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    Амитриптилин р-р для в/в и в/м введ. амп., 10 мг/мл, 2 мл, 10 шт.

    Цена 121 ₽
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    Реклама
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  • Мексидол форте таб. п/о. плен., 250 мг, 40 шт., 1 уп.
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    Мексидол форте таб. п/о. плен., 250 мг, 40 шт., 1 уп.

    Цена 792 ₽
  • Церепро р-р для в/в введ. и в/м введ. амп., 250 мг/мл, 4 мл, 5 шт.
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    Церепро р-р для в/в введ. и в/м введ. амп., 250 мг/мл, 4 мл, 5 шт.

    Цена 705 ₽
  • Энцетрон-СОЛОфарм р-р для в/в и в/м введ. амп., 125 мг/мл, 4 мл, 5 шт.
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    Энцетрон-СОЛОфарм р-р для в/в и в/м введ. амп., 125 мг/мл, 4 мл, 5 шт.

    Цена 252 ₽
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