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Мелатонин Эвалар таб. п/о плен., 3 мг, 20 шт., 1 уп.

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4.4
(148)
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Количество штук в упаковке, шт.: 20

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Коротко о товаре

Артикул Маркета
330821223
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
{"widgets":{"@card/SpecsList":{"/content/page/fancyPage/productSpecsList":{"wrapperProps":{"margins":{"top":4,"bottom":4}},"specsLimit":5,"title":"Коротко о товаре","titleSize":"14","type":"minimal","offset":"s","isHealthCategory":true,"forceShowWidget":true,"withFridge":true}}},"meta":{"/content/page/fancyPage/productSpecsList":{"name":"@card/SpecsList"}},"collections":{"minimalSpecs":{"5149787822294588100":{"specItems":[{"name":"Артикул Маркета","value":"330821223","withCopyValueButton":true},{"name":"тип препарата","value":"лекарственный препарат","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["27272850:1,0","34324371:35649313"]}}},{"name":"назначение","value":"десинхроноз, нарушение сна","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["36476390:36618389,36618157"]}}},{"name":"действующее вещество","value":"Мелатонин","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["27144131:28708746"]}}},{"name":"возраст","value":"от 18 лет"},{"name":"форма выпуска","value":"таблетки, покрытые пленочной оболочкой"},{"name":"страна-производитель","value":"Россия"}]}},"compactSpecs":{"5149787822294588100":{"specItems":[{"name":"Артикул Маркета","value":"330821223","withCopyValueButton":true},{"name":"Тип препарата","value":"Лекарственный препарат","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["27272850:1,0","34324371:35649313"]}}},{"name":"Назначение","value":"Десинхроноз, нарушение сна","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["36476390:36618389,36618157"]}}},{"name":"Действующее вещество","value":"Мелатонин","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["27144131:28708746"]}}},{"name":"Возраст","value":"От 18 лет"}]}},"fullSpecs":{"5149787822294588100":{"specItems":[{"name":"Тип препарата","value":"лекарственный препарат","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["34324371:35649313"]}}},{"name":"Органы и системы","value":"головной мозг, нервная система"},{"name":"Назначение","value":"десинхроноз, нарушение сна","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["36476390:36618389,36618157"]}}},{"name":"Показания к применению","value":"При расстройствах сна, в т.ч. обусловленных нарушением ритма \"сон-бодрствование\", таких как десинхроноз (резкая смена часовых поясов)."},{"name":"Противопоказания","value":"Гиперчувствительность к компонентам препарата, аутоиммунные заболевания, печеночная недостаточность, тяжелая почечная недостаточность, детский возраст до 18 лет, беременность, период грудного вскармливания."},{"name":"Состав","value":"На одну таблетку:\u003Cbr\u003EДействующее вещество: мелатонин - 3,00 мг.\u003Cbr\u003EВспомогательные вещества: целлюлоза микрокристаллическая - 172,72 мг, кальция гидрофосфат - 54,68 мг, кроскармеллоза натрия - 7,20 мг, кремния диоксид коллоидный - 1,20 мг, магния стеарат - 1,20 мг.\u003Cbr\u003EВспомогательные вещества оболочки: гипромеллоза (гидроксипропилметилцеллюлоза) - 4,00 мг, титана диоксид - 2,90 мг, полисорбат 80 - 1,32 мг, макрогол 4000 (полиэтиленгликоль 4000) - 0,89 мг, тальк - 0,89 мг."},{"name":"Действующее вещество","value":"Мелатонин","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["27144131:28708746"]}}},{"name":"Способ применения и дозы","value":"Внутрь.\u003Cbr\u003EПри нарушении сна - по 3 мг один раз в сутки за 30-40 минут до сна.\u003Cbr\u003EПри десинхронозе в качестве адаптогена при смене часовых поясов - за 1 день до перелета и в последующие 2-5 дней - по 3 мг за 30-40 минут до сна.\u003Cbr\u003EМаксимальная суточная доза - 6 мг.\u003Cbr\u003EПожилые пациенты\u003Cbr\u003EС возрастом происходит снижение метаболизма мелатонина, что необходимо учитывать при выборе режима дозирования для пожилых пациентов. С учетом этого у пациентов пожилого возраста, возможен прием препарата за 60-90 минут до сна.\u003Cbr\u003EПациентам с тяжелой почечной недостаточностью применение препарата не рекомендуется."},{"name":"Побочные действия","value":"Классификация частоты развития побочных эффектов согласно рекомендациям Всемирной Организации Здравоохранения:\u003Cbr\u003EОчень часто (≥1/10), часто (от ≥1/10 до \u003C1/10), нечасто (от ≥1/1000 до \u003C1/100), редко (от ≥1/10000 до \u003C1/1000), очень редко (\u003C1/10000), включая отдельные сообщения; частота неизвестна (по имеющимся данным установить частоту возникновения не представляется возможном).\u003Cbr\u003EИнфекционные и паразитарные заболевания:\u003Cbr\u003Eредко: опоясывающий герпес.\u003Cbr\u003EНарушения со стороны крови и лимфатической системы:\u003Cbr\u003Eредко: лейкопения, тромбоцитопения.\u003Cbr\u003EНарушения со стороны иммунной системы:\u003Cbr\u003Eчастота неизвестна: реакции гиперчувствительности.\u003Cbr\u003EНарушения со стороны обмена веществ и питания:\u003Cbr\u003Eредко: гипертриглицеридемия, гипокалиемия, гипонатриемия.\u003Cbr\u003EНарушение психики:\u003Cbr\u003Eнечасто: раздражительность, нервозность, беспокойство, бессонница, необычные сновидения, ночные кошмары, тревога;\u003Cbr\u003Eредко: перемены настроения, агрессия, ажитация, плаксивость, симптомы стресса, дезориентация, раннее утреннее пробуждение, повышение либидо, сниженное настроение, депрессия.\u003Cbr\u003EНарушения со стороны нервной системы:\u003Cbr\u003Eнечасто: мигрень, головная боль, вялость, психомоторная гиперактивность, головокружение, сонливость;\u003Cbr\u003Eредко: обморок, нарушение памяти, нарушение концентрации внимания, делирий, синдром \"беспокойных ног\", сновидное состояние, плохое качество сна, парестезии.\u003Cbr\u003EНарушения со стороны органа зрения:\u003Cbr\u003Eредко: снижение остроты зрения, нечеткость зрения, повышенное слезотечение.\u003Cbr\u003EНарушения со стороны органа слуха и лабиринтные нарушения:\u003Cbr\u003Eредко: вертиго, позиционное вертиго.\u003Cbr\u003EНарушения со стороны сердечно-сосудистой системы:\u003Cbr\u003Eнечасто: артериальная гипертензия;\u003Cbr\u003Eредко: стенокардия напряжения, ощущение сердцебиения, приливы.\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта:\u003Cbr\u003Eнечасто: абдоминальная боль, абдоминальная боль в верхней части живота, диспепсия, язвенный стоматит, сухость во рту, тошнота;\u003Cbr\u003Eредко: гастроэзофагеальная болезнь, желудочно-кишечное нарушение или расстройство, буллезный стоматит, язвенный глоссит, рвота, усиление перистальтики, вздутие живота, гиперсекреция слюны, неприятный запах изо рта, абдоминальный дискомфорт, дискинезия желудка, гастрит.\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей:\u003Cbr\u003Eнечасто: гипербилирубинемия.\u003Cbr\u003EНарушение со стороны кожи и подкожных тканей:\u003Cbr\u003Eнечасто: дерматит, потливость по ночам, зуд и генерализованный зуд, сыпь, сухость кожи;\u003Cbr\u003Eредко: экзема, эритема, дерматит рук, псориаз, генерализованная сыпь, зудящая сыпь, поражение ногтей;\u003Cbr\u003Eчастота неизвестна: отек Квинке, отек слизистой оболочки полости рта, отек языка.\u003Cbr\u003EНарушения со стороны скелетно-мышечной и соединительной ткани:\u003Cbr\u003Eнечасто: боль в конечностях.\u003Cbr\u003Eредко: артрит, мышечный спазм, боль в шее, ночные судороги.\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей:\u003Cbr\u003Eнечасто: глюкозурия, протеинурия;\u003Cbr\u003Eредко: полиурия, гематурия, никтурия.\u003Cbr\u003EНарушения со стороны половых органов и грудной железы:\u003Cbr\u003Eнечасто: менопаузальные симптомы;\u003Cbr\u003Eредко: приапизм, простатит; частота неизвестна: галакторея.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения:\u003Cbr\u003Eнечасто: астения, боль в груди;\u003Cbr\u003Eредко: утомляемость, боль, жажда.\u003Cbr\u003EЛабораторные и инструментальные данные:\u003Cbr\u003Eнечасто: отклонение от нормы лабораторных показателей функции печени, увеличение массы тела;\u003Cbr\u003Eредко: повышение активности \"печеночных\" трансаминаз, отклонение от нормы содержания электролитов в крови, отклонение от нормы результатов лабораторных тестов."},{"name":"Фармакологическое действие","value":"Мелатонин - синтетический аналог гормона шишковидного тела (эпифиза); синтезирован из аминокислот растительного происхождения.\u003Cbr\u003EОказывает адаптогенное, седативное, снотворное действие. Нормализует циркадные ритмы.\u003Cbr\u003EУвеличивает концентрацию гамма-аминомасляной кислоты (ГАМК) и серотонина в среднем мозге и гипоталамусе, изменяет активность пиридоксалькиназы, участвующей в синтезе ГАМК, дофамина и серотонина.\u003Cbr\u003EРегулирует цикл сон-бодрствование, суточные изменения локомоторной активности и температуры тела, положительно влияет на интеллектуально-мнестические функции мозга, на эмоционально-личностную сферу. Способствует организации биологического ритма и нормализации ночного сна, обладает снотворным эффектом. Улучшает качество сна, ускоряет засыпание, снижает число ночных пробуждений, улучшает самочувствие после утреннего пробуждения, не вызывает ощущение вялости, разбитости и усталости при пробуждении. Делает сновидения более яркими и эмоционально насыщенными.\u003Cbr\u003EАдаптирует организм к быстрой смене часовых поясов, снижает стрессовые реакции, регулирует нейроэндокринные функции.\u003Cbr\u003EАдаптирует организм метеочувствительных людей к изменениям погодных условий.\u003Cbr\u003EПроявляет иммуностимулирующие и антиоксидантные свойства.\u003Cbr\u003EНе вызывает привыкания и зависимости."},{"name":"Фармакологическая группа","value":"адаптогенное средство"},{"name":"Форма выпуска","value":"таблетки, покрытые пленочной оболочкой"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"При температуре не выше 25 °С, в оригинальной упаковке.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"По имеющимся литературным данным, применение мелатонина в суточной дозировке до 300 мг не вызывало клинически значимых нежелательных реакций. При приеме мелатонина в дозах от 3000 мг до 6600 мг в течение нескольких недель наблюдались такие симптомы как гиперемия, спазмы в брюшной полости, диарея, головная боль, скотома. При применении очень высоких доз мелатонина (до 1 г) наблюдалась непроизвольная потеря сознания. При передозировке возможно развитие сонливости.\u003Cbr\u003EЛечение - промывание желудка и применение активированного угля, симптоматическая терапия. Клиренс активного вещества предполагается в пределах 12 часов после приема внутрь."},{"name":"Применение при беременности и кормлении грудью","value":"Препарат противопоказан к применению при беременности и в период грудного вскармливания."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В период лечения необходимо воздержаться от управления транспортными средствами и занятий потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"С осторожностью:\u003Cbr\u003EВлияние различной степени почечной недостаточности на фармакокинетику мелатонина не изучено, поэтому таким пациентам мелатонин нужно применять с осторожностью.\u003Cbr\u003EВ период применения препарата Мелатонин Эвалар рекомендуется избегать пребывания на ярком свету.\u003Cbr\u003EНеобходимо проинформировать женщин, желающих забеременеть, о наличии у препарата слабого контрацептивного действия.\u003Cbr\u003EОтсутствуют клинические данные о применении мелатонина у больных с аутоиммунными заболеваниями, в связи с чем, применение у данной категории пациентов не рекомендуется. \u003Cbr\u003EСледует соблюдать осторожность в отношении пациентов, принимающих флувоксамин, который повышает концентрацию мелатонина за счет ингибирования его метаболизма изоферментами цитохрома Р450 (CYP): CYP1A2 и CYP2C19. Следует избегать такой комбинации.\u003Cbr\u003EСледует соблюдать осторожность в отношении пациентов, принимающих 5- и 8-метоксипсорален, который повышает концентрацию мелатонина вследствие ингибирования его метаболизма.\u003Cbr\u003EСледует соблюдать осторожность в отношении пациентов, принимающих циметидин, поскольку он повышает содержание мелатонина в плазме за счет ингибирования последнего.\u003Cbr\u003EКурение способно снизить концентрацию мелатонина за счет индукции изофермента CYP1A2.\u003Cbr\u003EСледует соблюдать осторожность в отношении пациентов, принимающих эстрогены (например, контрацептивы или заместительную гормональную терапию), которые увеличивают концентрацию мелатонина путем ингибирования их метаболизма изоферментами CYP1A1 и CYP1А2."},{"name":"Взаимодействие","value":"-Известно, что в концентрациях, значительно превышающих терапевтические, мелатонин индуцирует изофермент CYP3A in vitro. Клиническое значение этого явления до конца не выяснено. В случае развития признаков индукции следует рассмотреть вопрос о снижении дозы одновременно применяемых лекарственных средств.\u003Cbr\u003E- В концентрациях, значительно превышающих терапевтические, мелатонин не индуцирует изоферменты группы CYP1A in vitro. Следовательно, взаимодействие мелатонина с другими лекарственными средствами вследствие влияния мелатонина на изоферменты группы CYP1А, по-видимому, незначимо.\u003Cbr\u003E- Метаболизм мелатонина, главным образом, опосредован изоферментами CYP1A. Следовательно, возможно взаимодействие мелатонина с другими лекарственными средствами вследствие влияния мелатонина на изоферменты группы CYP1A.\u003Cbr\u003E- Ингибиторы изоферментов CYPA2, например, хинолоны, способны повышать экспозицию мелатонина.\u003Cbr\u003E- Индукторы изофермента CYP1A2, такие как карбамазепин и рифампицин, способны снижать плазменную концентрацию мелатонина.\u003Cbr\u003E- В современной литературе имеется множество данных, касающихся влияния агонистов/антагонистов адренергических и опиоидных рецепторов, антидепрессантов, ингибиторов простагландинов, бензодиазепинов, триптофана и алкоголя на секрецию эндогенного мелатонина. Исследования взаимного влияния этих препаратов на динамику или кинетику мелатонина не проводилось.\u003Cbr\u003EФармакодинамическое взаимодействие\u003Cbr\u003E- Во время приема мелатонина не следует употреблять алкоголь, так как он снижает эффективность препарата.\u003Cbr\u003E- Мелатонин потенцирует седативное действие бензодиазепиновых и небензодиазепиновых снотворных средств, таких как залеплон, золпидем и зопиклон. В ходе клинического исследования наблюдались четкие признаки транзиторного фармакодинамического взаимодействия между мелатонином и золпидемом спустя час после их приема. Комбинированное применение может приводить к прогрессирующему расстройству внимания, памяти и координации в сравнении с монотерапией золпидемом.\u003Cbr\u003E- В ходе исследований мелатонин назначался совместно с тиоридазином и имипрамином, препаратами, которые влияют на центральную нервную систему. Ни в одном из случаев не было выявлено клинически значимого фармакокинетического взаимодействия. Тем не менее, одновременное применение с мелатонином приводило к повышению ощущения спокойствия и к затруднениям в выполнении определенных заданий в сравнении с монотерапией имипрамином, а также к усилению чувства \"помутнения в голове\", в сравнении с монотерапией тиоридазином."},{"name":"Регистрационный номер","value":"ЛП-005295"},{"name":"Дата государственной регистрации","value":"14.01.2019"},{"name":"Владелец регистрационного удостоверения","value":"Эвалар","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["34324371:35649313","7893318:13131221"]}}},{"name":"Изготовитель","value":"Эвалар"},{"name":"Фасовщик","value":"Эвалар"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Мелатонин Эвалар","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["17796364:26106970"]}}},{"name":"Срок годности","value":"25 мес."}]}},"fullSpecsGrouped":{"5149787822294588100":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Органы и системы","value":"головной мозг, нервная система"},{"name":"Назначение","value":"десинхроноз, нарушение сна"},{"name":"Показания к применению","value":"При расстройствах сна, в т.ч. обусловленных нарушением ритма \"сон-бодрствование\", таких как десинхроноз (резкая смена часовых поясов)."},{"name":"Противопоказания","value":"Гиперчувствительность к компонентам препарата, аутоиммунные заболевания, печеночная недостаточность, тяжелая почечная недостаточность, детский возраст до 18 лет, беременность, период грудного вскармливания."},{"name":"Состав","value":"На одну таблетку:\u003Cbr\u003EДействующее вещество: мелатонин - 3,00 мг.\u003Cbr\u003EВспомогательные вещества: целлюлоза микрокристаллическая - 172,72 мг, кальция гидрофосфат - 54,68 мг, кроскармеллоза натрия - 7,20 мг, кремния диоксид коллоидный - 1,20 мг, магния стеарат - 1,20 мг.\u003Cbr\u003EВспомогательные вещества оболочки: гипромеллоза (гидроксипропилметилцеллюлоза) - 4,00 мг, титана диоксид - 2,90 мг, полисорбат 80 - 1,32 мг, макрогол 4000 (полиэтиленгликоль 4000) - 0,89 мг, тальк - 0,89 мг."},{"name":"Действующее вещество","value":"Мелатонин"},{"name":"Способ применения и дозы","value":"Внутрь.\u003Cbr\u003EПри нарушении сна - по 3 мг один раз в сутки за 30-40 минут до сна.\u003Cbr\u003EПри десинхронозе в качестве адаптогена при смене часовых поясов - за 1 день до перелета и в последующие 2-5 дней - по 3 мг за 30-40 минут до сна.\u003Cbr\u003EМаксимальная суточная доза - 6 мг.\u003Cbr\u003EПожилые пациенты\u003Cbr\u003EС возрастом происходит снижение метаболизма мелатонина, что необходимо учитывать при выборе режима дозирования для пожилых пациентов. С учетом этого у пациентов пожилого возраста, возможен прием препарата за 60-90 минут до сна.\u003Cbr\u003EПациентам с тяжелой почечной недостаточностью применение препарата не рекомендуется."},{"name":"Побочные действия","value":"Классификация частоты развития побочных эффектов согласно рекомендациям Всемирной Организации Здравоохранения:\u003Cbr\u003EОчень часто (≥1/10), часто (от ≥1/10 до \u003C1/10), нечасто (от ≥1/1000 до \u003C1/100), редко (от ≥1/10000 до \u003C1/1000), очень редко (\u003C1/10000), включая отдельные сообщения; частота неизвестна (по имеющимся данным установить частоту возникновения не представляется возможном).\u003Cbr\u003EИнфекционные и паразитарные заболевания:\u003Cbr\u003Eредко: опоясывающий герпес.\u003Cbr\u003EНарушения со стороны крови и лимфатической системы:\u003Cbr\u003Eредко: лейкопения, тромбоцитопения.\u003Cbr\u003EНарушения со стороны иммунной системы:\u003Cbr\u003Eчастота неизвестна: реакции гиперчувствительности.\u003Cbr\u003EНарушения со стороны обмена веществ и питания:\u003Cbr\u003Eредко: гипертриглицеридемия, гипокалиемия, гипонатриемия.\u003Cbr\u003EНарушение психики:\u003Cbr\u003Eнечасто: раздражительность, нервозность, беспокойство, бессонница, необычные сновидения, ночные кошмары, тревога;\u003Cbr\u003Eредко: перемены настроения, агрессия, ажитация, плаксивость, симптомы стресса, дезориентация, раннее утреннее пробуждение, повышение либидо, сниженное настроение, депрессия.\u003Cbr\u003EНарушения со стороны нервной системы:\u003Cbr\u003Eнечасто: мигрень, головная боль, вялость, психомоторная гиперактивность, головокружение, сонливость;\u003Cbr\u003Eредко: обморок, нарушение памяти, нарушение концентрации внимания, делирий, синдром \"беспокойных ног\", сновидное состояние, плохое качество сна, парестезии.\u003Cbr\u003EНарушения со стороны органа зрения:\u003Cbr\u003Eредко: снижение остроты зрения, нечеткость зрения, повышенное слезотечение.\u003Cbr\u003EНарушения со стороны органа слуха и лабиринтные нарушения:\u003Cbr\u003Eредко: вертиго, позиционное вертиго.\u003Cbr\u003EНарушения со стороны сердечно-сосудистой системы:\u003Cbr\u003Eнечасто: артериальная гипертензия;\u003Cbr\u003Eредко: стенокардия напряжения, ощущение сердцебиения, приливы.\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта:\u003Cbr\u003Eнечасто: абдоминальная боль, абдоминальная боль в верхней части живота, диспепсия, язвенный стоматит, сухость во рту, тошнота;\u003Cbr\u003Eредко: гастроэзофагеальная болезнь, желудочно-кишечное нарушение или расстройство, буллезный стоматит, язвенный глоссит, рвота, усиление перистальтики, вздутие живота, гиперсекреция слюны, неприятный запах изо рта, абдоминальный дискомфорт, дискинезия желудка, гастрит.\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей:\u003Cbr\u003Eнечасто: гипербилирубинемия.\u003Cbr\u003EНарушение со стороны кожи и подкожных тканей:\u003Cbr\u003Eнечасто: дерматит, потливость по ночам, зуд и генерализованный зуд, сыпь, сухость кожи;\u003Cbr\u003Eредко: экзема, эритема, дерматит рук, псориаз, генерализованная сыпь, зудящая сыпь, поражение ногтей;\u003Cbr\u003Eчастота неизвестна: отек Квинке, отек слизистой оболочки полости рта, отек языка.\u003Cbr\u003EНарушения со стороны скелетно-мышечной и соединительной ткани:\u003Cbr\u003Eнечасто: боль в конечностях.\u003Cbr\u003Eредко: артрит, мышечный спазм, боль в шее, ночные судороги.\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей:\u003Cbr\u003Eнечасто: глюкозурия, протеинурия;\u003Cbr\u003Eредко: полиурия, гематурия, никтурия.\u003Cbr\u003EНарушения со стороны половых органов и грудной железы:\u003Cbr\u003Eнечасто: менопаузальные симптомы;\u003Cbr\u003Eредко: приапизм, простатит; частота неизвестна: галакторея.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения:\u003Cbr\u003Eнечасто: астения, боль в груди;\u003Cbr\u003Eредко: утомляемость, боль, жажда.\u003Cbr\u003EЛабораторные и инструментальные данные:\u003Cbr\u003Eнечасто: отклонение от нормы лабораторных показателей функции печени, увеличение массы тела;\u003Cbr\u003Eредко: повышение активности \"печеночных\" трансаминаз, отклонение от нормы содержания электролитов в крови, отклонение от нормы результатов лабораторных тестов."},{"name":"Фармакологическое действие","value":"Мелатонин - синтетический аналог гормона шишковидного тела (эпифиза); синтезирован из аминокислот растительного происхождения.\u003Cbr\u003EОказывает адаптогенное, седативное, снотворное действие. Нормализует циркадные ритмы.\u003Cbr\u003EУвеличивает концентрацию гамма-аминомасляной кислоты (ГАМК) и серотонина в среднем мозге и гипоталамусе, изменяет активность пиридоксалькиназы, участвующей в синтезе ГАМК, дофамина и серотонина.\u003Cbr\u003EРегулирует цикл сон-бодрствование, суточные изменения локомоторной активности и температуры тела, положительно влияет на интеллектуально-мнестические функции мозга, на эмоционально-личностную сферу. Способствует организации биологического ритма и нормализации ночного сна, обладает снотворным эффектом. Улучшает качество сна, ускоряет засыпание, снижает число ночных пробуждений, улучшает самочувствие после утреннего пробуждения, не вызывает ощущение вялости, разбитости и усталости при пробуждении. Делает сновидения более яркими и эмоционально насыщенными.\u003Cbr\u003EАдаптирует организм к быстрой смене часовых поясов, снижает стрессовые реакции, регулирует нейроэндокринные функции.\u003Cbr\u003EАдаптирует организм метеочувствительных людей к изменениям погодных условий.\u003Cbr\u003EПроявляет иммуностимулирующие и антиоксидантные свойства.\u003Cbr\u003EНе вызывает привыкания и зависимости."},{"name":"Фармакологическая группа","value":"адаптогенное средство"},{"name":"Форма выпуска","value":"таблетки, покрытые пленочной оболочкой"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"При температуре не выше 25 °С, в оригинальной упаковке.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"По имеющимся литературным данным, применение мелатонина в суточной дозировке до 300 мг не вызывало клинически значимых нежелательных реакций. При приеме мелатонина в дозах от 3000 мг до 6600 мг в течение нескольких недель наблюдались такие симптомы как гиперемия, спазмы в брюшной полости, диарея, головная боль, скотома. При применении очень высоких доз мелатонина (до 1 г) наблюдалась непроизвольная потеря сознания. При передозировке возможно развитие сонливости.\u003Cbr\u003EЛечение - промывание желудка и применение активированного угля, симптоматическая терапия. Клиренс активного вещества предполагается в пределах 12 часов после приема внутрь."},{"name":"Применение при беременности и кормлении грудью","value":"Препарат противопоказан к применению при беременности и в период грудного вскармливания."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В период лечения необходимо воздержаться от управления транспортными средствами и занятий потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"С осторожностью:\u003Cbr\u003EВлияние различной степени почечной недостаточности на фармакокинетику мелатонина не изучено, поэтому таким пациентам мелатонин нужно применять с осторожностью.\u003Cbr\u003EВ период применения препарата Мелатонин Эвалар рекомендуется избегать пребывания на ярком свету.\u003Cbr\u003EНеобходимо проинформировать женщин, желающих забеременеть, о наличии у препарата слабого контрацептивного действия.\u003Cbr\u003EОтсутствуют клинические данные о применении мелатонина у больных с аутоиммунными заболеваниями, в связи с чем, применение у данной категории пациентов не рекомендуется. \u003Cbr\u003EСледует соблюдать осторожность в отношении пациентов, принимающих флувоксамин, который повышает концентрацию мелатонина за счет ингибирования его метаболизма изоферментами цитохрома Р450 (CYP): CYP1A2 и CYP2C19. Следует избегать такой комбинации.\u003Cbr\u003EСледует соблюдать осторожность в отношении пациентов, принимающих 5- и 8-метоксипсорален, который повышает концентрацию мелатонина вследствие ингибирования его метаболизма.\u003Cbr\u003EСледует соблюдать осторожность в отношении пациентов, принимающих циметидин, поскольку он повышает содержание мелатонина в плазме за счет ингибирования последнего.\u003Cbr\u003EКурение способно снизить концентрацию мелатонина за счет индукции изофермента CYP1A2.\u003Cbr\u003EСледует соблюдать осторожность в отношении пациентов, принимающих эстрогены (например, контрацептивы или заместительную гормональную терапию), которые увеличивают концентрацию мелатонина путем ингибирования их метаболизма изоферментами CYP1A1 и CYP1А2."},{"name":"Взаимодействие","value":"-Известно, что в концентрациях, значительно превышающих терапевтические, мелатонин индуцирует изофермент CYP3A in vitro. Клиническое значение этого явления до конца не выяснено. В случае развития признаков индукции следует рассмотреть вопрос о снижении дозы одновременно применяемых лекарственных средств.\u003Cbr\u003E- В концентрациях, значительно превышающих терапевтические, мелатонин не индуцирует изоферменты группы CYP1A in vitro. Следовательно, взаимодействие мелатонина с другими лекарственными средствами вследствие влияния мелатонина на изоферменты группы CYP1А, по-видимому, незначимо.\u003Cbr\u003E- Метаболизм мелатонина, главным образом, опосредован изоферментами CYP1A. Следовательно, возможно взаимодействие мелатонина с другими лекарственными средствами вследствие влияния мелатонина на изоферменты группы CYP1A.\u003Cbr\u003E- Ингибиторы изоферментов CYPA2, например, хинолоны, способны повышать экспозицию мелатонина.\u003Cbr\u003E- Индукторы изофермента CYP1A2, такие как карбамазепин и рифампицин, способны снижать плазменную концентрацию мелатонина.\u003Cbr\u003E- В современной литературе имеется множество данных, касающихся влияния агонистов/антагонистов адренергических и опиоидных рецепторов, антидепрессантов, ингибиторов простагландинов, бензодиазепинов, триптофана и алкоголя на секрецию эндогенного мелатонина. Исследования взаимного влияния этих препаратов на динамику или кинетику мелатонина не проводилось.\u003Cbr\u003EФармакодинамическое взаимодействие\u003Cbr\u003E- Во время приема мелатонина не следует употреблять алкоголь, так как он снижает эффективность препарата.\u003Cbr\u003E- Мелатонин потенцирует седативное действие бензодиазепиновых и небензодиазепиновых снотворных средств, таких как залеплон, золпидем и зопиклон. В ходе клинического исследования наблюдались четкие признаки транзиторного фармакодинамического взаимодействия между мелатонином и золпидемом спустя час после их приема. Комбинированное применение может приводить к прогрессирующему расстройству внимания, памяти и координации в сравнении с монотерапией золпидемом.\u003Cbr\u003E- В ходе исследований мелатонин назначался совместно с тиоридазином и имипрамином, препаратами, которые влияют на центральную нервную систему. Ни в одном из случаев не было выявлено клинически значимого фармакокинетического взаимодействия. Тем не менее, одновременное применение с мелатонином приводило к повышению ощущения спокойствия и к затруднениям в выполнении определенных заданий в сравнении с монотерапией имипрамином, а также к усилению чувства \"помутнения в голове\", в сравнении с монотерапией тиоридазином."},{"name":"Регистрационный номер","value":"ЛП-005295"},{"name":"Дата государственной регистрации","value":"14.01.2019"},{"name":"Владелец регистрационного удостоверения","value":"Эвалар"},{"name":"Изготовитель","value":"Эвалар"},{"name":"Фасовщик","value":"Эвалар"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Мелатонин Эвалар"},{"name":"Срок годности","value":"25 мес."}]}],"transitionId":"tr_5641810474523731579"}}}}
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Цена с картой Яндекс Пэй:318 ₽

Скидка: 1%
–1 %
Вместо: 321 ₽
  • 18 июня, курьер Маркета • 249 ₽
  • Завтра, самовывоз • 0 ₽
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POLZAru
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38Котзывов
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  • Сонные+ таб., 30 шт., 1 уп.
    –33 %
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    Сонные+ таб., 30 шт., 1 уп.

    Рейтинг товара: 4.1 из 5
    на основе 149 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 269 ₽ вместо 275
    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  • Формула Спокойствия Триптофан капс., 15 шт.
    –1 %
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    Формула Спокойствия Триптофан капс., 15 шт.

    Рейтинг товара: 4.6 из 5
    на основе 29 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 452 ₽ вместо 457
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  • Формула сна экспресс таб. д/рассас., 40 шт.
    –1 %
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    Формула сна экспресс таб. д/рассас., 40 шт.

    Рейтинг товара: 3.7 из 5
    на основе 3 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 483 ₽ вместо 488
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  • Реасон Мелатонин капс., 2 мг, 60 шт., 1 уп.
    –1 %
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    Реасон Мелатонин капс., 2 мг, 60 шт., 1 уп.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    С картой  Пэй
    Цена с картой Яндекс Пэй 772 ₽ вместо 780
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  • Гинкго Билоба Эвалар таб., 0.5 г, 100 шт., 1 уп.
    –11 %
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    Гинкго Билоба Эвалар таб., 0.5 г, 100 шт., 1 уп.

    Рейтинг товара: 4.8 из 5
    на основе 339 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 1 296 ₽ вместо 1 309
    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Билоба Эвалар таб., 0.5 г, 100 шт., 1 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  • Формула сна усиленная фито-мелатонином капс., 30 шт.
    –1 %
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    Формула сна усиленная фито-мелатонином капс., 30 шт.

    Рейтинг товара: 4 из 5
    на основе 11 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 613 ₽ вместо 619
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  • GLS Триптофан капс., 500 мг, 0.25 г, 90 шт.
    –10 %
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    GLS Триптофан капс., 500 мг, 0.25 г, 90 шт.

    Рейтинг товара: 4.8 из 5
    на основе 24 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 540 ₽ вместо 550
    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Триптофан капс., 500 мг, 0.25 г, 90 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  • Good Sleep спрей фл., 30 мл, 10 г, 1 шт., мятный, 1 уп.
    –34 %
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    Good Sleep спрей фл., 30 мл, 10 г, 1 шт., мятный, 1 уп.

    Рейтинг товара: 4.6 из 5
    на основе 223 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 1 185 ₽ вместо 1 209
    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  • Формула сна таб., 40 шт., 1 уп.
    –1 %
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    Формула сна таб., 40 шт., 1 уп.

    Рейтинг товара: 4.2 из 5
    на основе 21 оценка
    С картой  Пэй
    Цена с картой Яндекс Пэй 409 ₽ вместо 413
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  • Релаксозан День таб., 40 шт.
    –2 %
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    Релаксозан День таб., 40 шт.

    Рейтинг товара: 4.7 из 5
    на основе 124 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 669 ₽ вместо 683
    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День таб., 40 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  • Natrol Melatonin таб., 3 мг, 100 г, 60 шт.
    –28 %
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    Natrol Melatonin таб., 3 мг, 100 г, 60 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    С картой  Пэй
    Цена с картой Яндекс Пэй 1 558 ₽ вместо 1 590
    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Melatonin таб., 3 мг, 100 г, 60 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Инструкция

Показания к применению

При расстройствах сна, в т.ч. обусловленных нарушением ритма "сон-бодрствование", таких как десинхроноз (резкая смена часовых поясов).

Противопоказания

Гиперчувствительность к компонентам препарата, аутоиммунные заболевания, печеночная недостаточность, тяжелая почечная недостаточность, детский возраст до 18 лет, беременность, период грудного вскармливания.

Способ применения и дозы

Внутрь.
При нарушении сна - по 3 мг один раз в сутки за 30-40 минут до сна.
При десинхронозе в качестве адаптогена при смене часовых поясов - за 1 день до перелета и в последующие 2-5 дней - по 3 мг за 30-40 минут до сна.
Максимальная суточная доза - 6 мг.
Пожилые пациенты
С возрастом происходит снижение метаболизма мелатонина, что необходимо учитывать при выборе режима дозирования для пожилых пациентов. С учетом этого у пациентов пожилого возраста, возможен прием препарата за 60-90 минут до сна.
Пациентам с тяжелой почечной недостаточностью применение препарата не рекомендуется.
Полная инструкция
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Мелатонин Эвалар таб. п/о плен.
Мелатонин Эвалар таб. п/о плен., 3 мг, 20 шт., 1 уп.
4.4
(148)
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13 вопросов
Инструкция

Цена с картой Яндекс Пэй:318 ₽

Скидка: 1%
–1 %
Вместо: 321 ₽
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4.4
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У продавца:148 оценок·49 отзывов
У всех продавцов:710 оценок·295 отзывов
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user avatar
Год назад • Анна Ивановна • Куплен на Маркете
Достоинства: Отличный препарат. Работает хорошо. Засыпаю после приëма мелатонина минут через 40-50. Если ночью просыпаюсь, то тут же снова засыпаю. Утром пробуждение без проблем, никакой сонливости.
Недостатки: не обнаружила
Комментарий: Рекомендую к покупке тем, у кого есть проблемы со сном, особенно когда пробуждение среди ночи, а потом долго не уснуть.
user avatar
7 месяцев назад • Влад Кшнякин • Куплен на Маркете
Комментарий: Хорошие таблетки для улучшения сна, периодически пользуюсь при нарушении режима, очень помогают (это не снотворное, а натуральный гормон сна)
user avatar
Год назад • Александр • Куплен на Маркете
Достоинства: Работает. Цена вроде ок. Таблеток в пачке много. На следующий день не варёный как колбаса, разум чист.
Недостатки: Жаль что не бесплатно :D
Комментарий: Слава России!
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    Цена 311 ₽ вместо 742
  • Формула сна экспресс таб. д/рассас., 40 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778173019_4/content/content/gallery":{"title":"Формула сна экспресс таб. д/рассас., 40 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/4377400/img_id746274301069913336.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4377400/img_id746274301069913336.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4377400/img_id746274301069913336.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4377400/img_id746274301069913336.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4377400/img_id746274301069913336.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4377400/img_id746274301069913336.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4383514/img_id3868804356612201078.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4383514/img_id3868804356612201078.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4383514/img_id3868804356612201078.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4383514/img_id3868804356612201078.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4383514/img_id3868804356612201078.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4383514/img_id3868804356612201078.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQguXp7baxn4o/EhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCNuI888GENyJ9LECGNW7oQYg7dnBBw==","sign":"j9gU3lcv4cIUY8UMb1KXpzxpa/Gr+PIRdeJG4SZ3oNM="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778173019_4/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
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    Формула сна экспресс таб. д/рассас., 40 шт.

    Цена 483 ₽ вместо 488
  • Магний В6 таб., 1.25 г, 60 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:652158125_5/content/content/gallery":{"title":"Магний В6 таб., 1.25 г, 60 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/8109518/img_id843237772370969829.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/8109518/img_id843237772370969829.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/8109518/img_id843237772370969829.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/8109518/img_id843237772370969829.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/8109518/img_id843237772370969829.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/8109518/img_id843237772370969829.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4377400/img_id2614823306433533188.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4377400/img_id2614823306433533188.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4377400/img_id2614823306433533188.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4377400/img_id2614823306433533188.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4377400/img_id2614823306433533188.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4377400/img_id2614823306433533188.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQguXp7baxn4o/EhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCK3J/LYCEN61xbH5AhjVu6EGIJnDBQ==","sign":"lIqkPqykWvnsOETsvTXvOOuFiUocNWS+ON+sAlj/7sk="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:652158125_5/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
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    Магний В6 таб., 1.25 г, 60 шт.

    Цена 382 ₽ вместо 407
  • Панкреатин таб. п/о кш/раств. (блистеры), 25 ЕД, 20 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1400799517_6/content/content/toggleWishlist":{"skuId":"227830357","productId":1400799517,"offerId":"7o_qaQgAWJn69KRM8Mb35A","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQguXp7baxn4o/EhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIVCJ2C+psFENXU0WwY6NzQByDa2cEH","sign":"bqzxFZxGIvfxSR9uzAWa63+ZHJ8jHbI7U9RYe/YuWUI="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1400799517_6/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Панкреатин таб. п/о кш/раств. (блистеры), 25 ЕД, 20 шт.

    Цена 35 ₽
  • Эвалар Витамин Д3 максимум 2000 МЕ 120 капсул
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    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1821930825_7/content/content/toggleWishlist":{"skuId":"101960303901","productId":1821930825,"offerId":"3F5uw7oAP-j4IZvqpoD1_w","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQguXp7baxn4o/EhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCMnq4eQGEJ2Ku+r7AhjVu6EGIJnDBQ==","sign":"EkiGTIoahCYQNnZ0k0kVG1tVKyybDPbBZWQ5EFDuWQI="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1821930825_7/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Эвалар Витамин Д3 максимум 2000 МЕ 120 капсул

    Цена 531 ₽ вместо 596
  • {"widgets":{"@light/BannerCurtain":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_101_8/content/content/content/bannerCurtain":{"advertisementId":2084241,"impression":"/safeclick/data=SpQw45JhDGE6zDtOdUQO_JCwqBb4s67N0LS6ZB0-raZgUV1C7RjDXJhFEtsPLIvnprl66Gh_6qw5WRV_oUiznqBbzgkdKDUMGByILj2WdH5eQOqmg6UfjKrX_R2gQZ-QcB0c0hbpk1wnoCOJd7aMKFrhTZYA34T585XJ03wmxu2uK3vAc8XliOxnJQgx4izz85XTMkLWgHcQlmffR1rES7D-9bZXsmP3VzeQMAS4jg9qhQ-HZHCs5AFqsUoRiPaCRtKD_1WE_SBYqdxL428Er2H2VgGZ9zEFK0mDJEFVRySq9VRQIW_nStE7uKC2SDmA7i5DjptCY3pATYAGJZfrAOdhVs-bXvhqmJfDrkEnc-Wv_NkuSttu2E9wxtiuqEC7yMLmEDOzxRZnHm_r1i9QL9DWG5z8eXx2XaPPJBQZ7qNxyOQbuynLM3XjexfcHIGFAHxHEnOkNh2vzkSJZKRnT85fKj7NVNq7XRg1OJfyyObKU9LupyEmsHtUFu7iny3OUYTkkmC3WrF3Rapurint2QZt9VBlihrx9TN8OduzogmUybqGdxLzvHOPaXPRnn9H0DVWteR4z4sn_4uTN7oIso0cLlKH8ebnRU-v_GjmPYYOHZfmWCL_PT74qyvRl4K7AOWvHNhK8UChMVsW0YAFxUSFEA6NONBuzxJKfGCZt_ZOAV02mE6wois30DZfXv3PG_DibHVt8svBG35YvS20uE4Ws3IzzgQZYT7FLJOCwtMEPXl7pBrKS1d82pZtvNKrbp2MZqxoY2ls87A5xj7sxitOcsXAQNn3PNrP_8uACnoKCYNoed3FylzYGZz4JAFxK2grFZIAKi__LFZE8YSLcw4AMySSRsVIc2mcJdx5kesk9AGW14iD2idPmioSIp0y1YmwqooqtFHnkTEdZh8z5_zYoPQ60Jer8kapQQK4IhnT7CiSNaqCF71GR-4O2UqPr_tnDQFqguuZ2dIdLZC6Omv6Fuuqr2nGuyPT4psOwfHem--RB4uQ1xkMDZQ816aW2BP6fsPjTEd4sdgpxmRGsBW_ZMg0XlMDe3oPtzK7HS3ej4ALaeurpyMXeiQlsX-nFlySqjizen6ICwBMOFv5ig,,/b64e=1/sign=d6cf2f9e38f81543ca66e604d2eb13e1/keyno=MARKET_1/*"}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_101_8/content/content/content/bannerCurtain":{"name":"@light/BannerCurtain"}}}
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    Реклама
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  • Реасон Мелатонин капс., 2 мг, 60 шт., 1 уп.
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    Реасон Мелатонин капс., 2 мг, 60 шт., 1 уп.

    Цена 772 ₽ вместо 780
  • Витамин Д3 + К2 таб. жев., 1200 МЕ, 0.22 г, 60 шт.
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    Витамин Д3 + К2 таб. жев., 1200 МЕ, 0.22 г, 60 шт.

    Цена 408 ₽ вместо 412
  • Сонные+ таб., 30 шт., 1 уп.
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    Сонные+ таб., 30 шт., 1 уп.

    Цена 269 ₽ вместо 399
  • Формула сна усиленная фито-мелатонином капс., 30 шт.
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    Формула сна усиленная фито-мелатонином капс., 30 шт.

    Цена 613 ₽ вместо 619
  • Формула сна таб., 40 шт., 1 уп.
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    Формула сна таб., 40 шт., 1 уп.

    Цена 409 ₽ вместо 413
  • Мезим Форте таб. п/о, 20 шт.
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    Мезим Форте таб. п/о, 20 шт.

    Цена 103 ₽ вместо 105
  • Полисорб МП пор. д/приг. сусп. д/вн. приема, 12 г
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    Полисорб МП пор. д/приг. сусп. д/вн. приема, 12 г

    Цена 274 ₽ вместо 277
  • GLS Триптофан капс., 500 мг, 0.25 г, 90 шт.
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    GLS Триптофан капс., 500 мг, 0.25 г, 90 шт.

    Цена 540 ₽ вместо 600
  • Гинкго Билоба Эвалар таб., 0.5 г, 40 шт., 1 уп.
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    Гинкго Билоба Эвалар таб., 0.5 г, 40 шт., 1 уп.

    Цена 428 ₽ вместо 432
  • Упсарин упса таб. шип., 500 мг, 16 шт.
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    Упсарин упса таб. шип., 500 мг, 16 шт.

    Цена 296 ₽ вместо 299
  • Релаксозан День таб., 20 шт.
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    Релаксозан День таб., 20 шт.

    Цена 488 ₽ вместо 493
  • Natrol Melatonin таб., 3 мг, 100 г, 60 шт.
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    Natrol Melatonin таб., 3 мг, 100 г, 60 шт.

    Цена 1 558 ₽ вместо 2 150
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    Реклама
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  • Good Sleep спрей фл., 30 мл, 10 г, 1 шт., мятный, 1 уп.
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    Good Sleep спрей фл., 30 мл, 10 г, 1 шт., мятный, 1 уп.

    Цена 1 185 ₽ вместо 1 790
  • БиоГая Пробиотик капли детск. фл., 5 мл, 1 уп.
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    БиоГая Пробиотик капли детск. фл., 5 мл, 1 уп.

    Цена 1 752 ₽ вместо 3 500
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