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Мелатонин Эвалар таб. п/о плен., 3 мг, 20 шт., 1 уп.

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Количество штук в упаковке, шт.: 20

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Коротко о товаре

Артикул Маркета
330821223
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
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С учетом этого у пациентов пожилого возраста, возможен прием препарата за 60-90 минут до сна.\u003Cbr\u003EПациентам с тяжелой почечной недостаточностью применение препарата не рекомендуется."},{"name":"Побочные действия","value":"Классификация частоты развития побочных эффектов согласно рекомендациям Всемирной Организации Здравоохранения:\u003Cbr\u003EОчень часто (≥1/10), часто (от ≥1/10 до \u003C1/10), нечасто (от ≥1/1000 до \u003C1/100), редко (от ≥1/10000 до \u003C1/1000), очень редко (\u003C1/10000), включая отдельные сообщения; частота неизвестна (по имеющимся данным установить частоту возникновения не представляется возможном).\u003Cbr\u003EИнфекционные и паразитарные заболевания:\u003Cbr\u003Eредко: опоясывающий герпес.\u003Cbr\u003EНарушения со стороны крови и лимфатической системы:\u003Cbr\u003Eредко: лейкопения, тромбоцитопения.\u003Cbr\u003EНарушения со стороны иммунной системы:\u003Cbr\u003Eчастота неизвестна: реакции гиперчувствительности.\u003Cbr\u003EНарушения со стороны обмена веществ и питания:\u003Cbr\u003Eредко: гипертриглицеридемия, гипокалиемия, гипонатриемия.\u003Cbr\u003EНарушение психики:\u003Cbr\u003Eнечасто: раздражительность, нервозность, беспокойство, бессонница, необычные сновидения, ночные кошмары, тревога;\u003Cbr\u003Eредко: перемены настроения, агрессия, ажитация, плаксивость, симптомы стресса, дезориентация, раннее утреннее пробуждение, повышение либидо, сниженное настроение, депрессия.\u003Cbr\u003EНарушения со стороны нервной системы:\u003Cbr\u003Eнечасто: мигрень, головная боль, вялость, психомоторная гиперактивность, головокружение, сонливость;\u003Cbr\u003Eредко: обморок, нарушение памяти, нарушение концентрации внимания, делирий, синдром \"беспокойных ног\", сновидное состояние, плохое качество сна, парестезии.\u003Cbr\u003EНарушения со стороны органа зрения:\u003Cbr\u003Eредко: снижение остроты зрения, нечеткость зрения, повышенное слезотечение.\u003Cbr\u003EНарушения со стороны органа слуха и лабиринтные нарушения:\u003Cbr\u003Eредко: вертиго, позиционное вертиго.\u003Cbr\u003EНарушения со стороны сердечно-сосудистой системы:\u003Cbr\u003Eнечасто: артериальная гипертензия;\u003Cbr\u003Eредко: стенокардия напряжения, ощущение сердцебиения, приливы.\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта:\u003Cbr\u003Eнечасто: абдоминальная боль, абдоминальная боль в верхней части живота, диспепсия, язвенный стоматит, сухость во рту, тошнота;\u003Cbr\u003Eредко: гастроэзофагеальная болезнь, желудочно-кишечное нарушение или расстройство, буллезный стоматит, язвенный глоссит, рвота, усиление перистальтики, вздутие живота, гиперсекреция слюны, неприятный запах изо рта, абдоминальный дискомфорт, дискинезия желудка, гастрит.\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей:\u003Cbr\u003Eнечасто: гипербилирубинемия.\u003Cbr\u003EНарушение со стороны кожи и подкожных тканей:\u003Cbr\u003Eнечасто: дерматит, потливость по ночам, зуд и генерализованный зуд, сыпь, сухость кожи;\u003Cbr\u003Eредко: экзема, эритема, дерматит рук, псориаз, генерализованная сыпь, зудящая сыпь, поражение ногтей;\u003Cbr\u003Eчастота неизвестна: отек Квинке, отек слизистой оболочки полости рта, отек языка.\u003Cbr\u003EНарушения со стороны скелетно-мышечной и соединительной ткани:\u003Cbr\u003Eнечасто: боль в конечностях.\u003Cbr\u003Eредко: артрит, мышечный спазм, боль в шее, ночные судороги.\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей:\u003Cbr\u003Eнечасто: глюкозурия, протеинурия;\u003Cbr\u003Eредко: полиурия, гематурия, никтурия.\u003Cbr\u003EНарушения со стороны половых органов и грудной железы:\u003Cbr\u003Eнечасто: менопаузальные симптомы;\u003Cbr\u003Eредко: приапизм, простатит; частота неизвестна: галакторея.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения:\u003Cbr\u003Eнечасто: астения, боль в груди;\u003Cbr\u003Eредко: утомляемость, боль, жажда.\u003Cbr\u003EЛабораторные и инструментальные данные:\u003Cbr\u003Eнечасто: отклонение от нормы лабораторных показателей функции печени, увеличение массы тела;\u003Cbr\u003Eредко: повышение активности \"печеночных\" трансаминаз, отклонение от нормы содержания электролитов в крови, отклонение от нормы результатов лабораторных тестов."},{"name":"Фармакологическое действие","value":"Мелатонин - синтетический аналог гормона шишковидного тела (эпифиза); синтезирован из аминокислот растительного происхождения.\u003Cbr\u003EОказывает адаптогенное, седативное, снотворное действие. Нормализует циркадные ритмы.\u003Cbr\u003EУвеличивает концентрацию гамма-аминомасляной кислоты (ГАМК) и серотонина в среднем мозге и гипоталамусе, изменяет активность пиридоксалькиназы, участвующей в синтезе ГАМК, дофамина и серотонина.\u003Cbr\u003EРегулирует цикл сон-бодрствование, суточные изменения локомоторной активности и температуры тела, положительно влияет на интеллектуально-мнестические функции мозга, на эмоционально-личностную сферу. Способствует организации биологического ритма и нормализации ночного сна, обладает снотворным эффектом. Улучшает качество сна, ускоряет засыпание, снижает число ночных пробуждений, улучшает самочувствие после утреннего пробуждения, не вызывает ощущение вялости, разбитости и усталости при пробуждении. Делает сновидения более яркими и эмоционально насыщенными.\u003Cbr\u003EАдаптирует организм к быстрой смене часовых поясов, снижает стрессовые реакции, регулирует нейроэндокринные функции.\u003Cbr\u003EАдаптирует организм метеочувствительных людей к изменениям погодных условий.\u003Cbr\u003EПроявляет иммуностимулирующие и антиоксидантные свойства.\u003Cbr\u003EНе вызывает привыкания и зависимости."},{"name":"Фармакологическая группа","value":"адаптогенное средство"},{"name":"Форма выпуска","value":"таблетки, покрытые пленочной оболочкой"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"При температуре не выше 25 °С, в оригинальной упаковке.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"По имеющимся литературным данным, применение мелатонина в суточной дозировке до 300 мг не вызывало клинически значимых нежелательных реакций. При приеме мелатонина в дозах от 3000 мг до 6600 мг в течение нескольких недель наблюдались такие симптомы как гиперемия, спазмы в брюшной полости, диарея, головная боль, скотома. При применении очень высоких доз мелатонина (до 1 г) наблюдалась непроизвольная потеря сознания. При передозировке возможно развитие сонливости.\u003Cbr\u003EЛечение - промывание желудка и применение активированного угля, симптоматическая терапия. Клиренс активного вещества предполагается в пределах 12 часов после приема внутрь."},{"name":"Применение при беременности и кормлении грудью","value":"Препарат противопоказан к применению при беременности и в период грудного вскармливания."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В период лечения необходимо воздержаться от управления транспортными средствами и занятий потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"С осторожностью:\u003Cbr\u003EВлияние различной степени почечной недостаточности на фармакокинетику мелатонина не изучено, поэтому таким пациентам мелатонин нужно применять с осторожностью.\u003Cbr\u003EВ период применения препарата Мелатонин Эвалар рекомендуется избегать пребывания на ярком свету.\u003Cbr\u003EНеобходимо проинформировать женщин, желающих забеременеть, о наличии у препарата слабого контрацептивного действия.\u003Cbr\u003EОтсутствуют клинические данные о применении мелатонина у больных с аутоиммунными заболеваниями, в связи с чем, применение у данной категории пациентов не рекомендуется. \u003Cbr\u003EСледует соблюдать осторожность в отношении пациентов, принимающих флувоксамин, который повышает концентрацию мелатонина за счет ингибирования его метаболизма изоферментами цитохрома Р450 (CYP): CYP1A2 и CYP2C19. Следует избегать такой комбинации.\u003Cbr\u003EСледует соблюдать осторожность в отношении пациентов, принимающих 5- и 8-метоксипсорален, который повышает концентрацию мелатонина вследствие ингибирования его метаболизма.\u003Cbr\u003EСледует соблюдать осторожность в отношении пациентов, принимающих циметидин, поскольку он повышает содержание мелатонина в плазме за счет ингибирования последнего.\u003Cbr\u003EКурение способно снизить концентрацию мелатонина за счет индукции изофермента CYP1A2.\u003Cbr\u003EСледует соблюдать осторожность в отношении пациентов, принимающих эстрогены (например, контрацептивы или заместительную гормональную терапию), которые увеличивают концентрацию мелатонина путем ингибирования их метаболизма изоферментами CYP1A1 и CYP1А2."},{"name":"Взаимодействие","value":"-Известно, что в концентрациях, значительно превышающих терапевтические, мелатонин индуцирует изофермент CYP3A in vitro. Клиническое значение этого явления до конца не выяснено. В случае развития признаков индукции следует рассмотреть вопрос о снижении дозы одновременно применяемых лекарственных средств.\u003Cbr\u003E- В концентрациях, значительно превышающих терапевтические, мелатонин не индуцирует изоферменты группы CYP1A in vitro. Следовательно, взаимодействие мелатонина с другими лекарственными средствами вследствие влияния мелатонина на изоферменты группы CYP1А, по-видимому, незначимо.\u003Cbr\u003E- Метаболизм мелатонина, главным образом, опосредован изоферментами CYP1A. Следовательно, возможно взаимодействие мелатонина с другими лекарственными средствами вследствие влияния мелатонина на изоферменты группы CYP1A.\u003Cbr\u003E- Ингибиторы изоферментов CYPA2, например, хинолоны, способны повышать экспозицию мелатонина.\u003Cbr\u003E- Индукторы изофермента CYP1A2, такие как карбамазепин и рифампицин, способны снижать плазменную концентрацию мелатонина.\u003Cbr\u003E- В современной литературе имеется множество данных, касающихся влияния агонистов/антагонистов адренергических и опиоидных рецепторов, антидепрессантов, ингибиторов простагландинов, бензодиазепинов, триптофана и алкоголя на секрецию эндогенного мелатонина. Исследования взаимного влияния этих препаратов на динамику или кинетику мелатонина не проводилось.\u003Cbr\u003EФармакодинамическое взаимодействие\u003Cbr\u003E- Во время приема мелатонина не следует употреблять алкоголь, так как он снижает эффективность препарата.\u003Cbr\u003E- Мелатонин потенцирует седативное действие бензодиазепиновых и небензодиазепиновых снотворных средств, таких как залеплон, золпидем и зопиклон. В ходе клинического исследования наблюдались четкие признаки транзиторного фармакодинамического взаимодействия между мелатонином и золпидемом спустя час после их приема. Комбинированное применение может приводить к прогрессирующему расстройству внимания, памяти и координации в сравнении с монотерапией золпидемом.\u003Cbr\u003E- В ходе исследований мелатонин назначался совместно с тиоридазином и имипрамином, препаратами, которые влияют на центральную нервную систему. Ни в одном из случаев не было выявлено клинически значимого фармакокинетического взаимодействия. Тем не менее, одновременное применение с мелатонином приводило к повышению ощущения спокойствия и к затруднениям в выполнении определенных заданий в сравнении с монотерапией имипрамином, а также к усилению чувства \"помутнения в голове\", в сравнении с монотерапией тиоридазином."},{"name":"Регистрационный номер","value":"ЛП-005295"},{"name":"Дата государственной регистрации","value":"14.01.2019"},{"name":"Владелец регистрационного удостоверения","value":"Эвалар","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["34324371:35649313","7893318:13131221"]}}},{"name":"Изготовитель","value":"Эвалар"},{"name":"Фасовщик","value":"Эвалар"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Мелатонин Эвалар","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["17796364:26106970"]}}},{"name":"Срок годности","value":"25 мес."}]}},"fullSpecsGrouped":{"5149787822294588100":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Органы и системы","value":"головной мозг, нервная система"},{"name":"Назначение","value":"десинхроноз, нарушение сна"},{"name":"Показания к применению","value":"При расстройствах сна, в т.ч. обусловленных нарушением ритма \"сон-бодрствование\", таких как десинхроноз (резкая смена часовых поясов)."},{"name":"Противопоказания","value":"Гиперчувствительность к компонентам препарата, аутоиммунные заболевания, печеночная недостаточность, тяжелая почечная недостаточность, детский возраст до 18 лет, беременность, период грудного вскармливания."},{"name":"Состав","value":"На одну таблетку:\u003Cbr\u003EДействующее вещество: мелатонин - 3,00 мг.\u003Cbr\u003EВспомогательные вещества: целлюлоза микрокристаллическая - 172,72 мг, кальция гидрофосфат - 54,68 мг, кроскармеллоза натрия - 7,20 мг, кремния диоксид коллоидный - 1,20 мг, магния стеарат - 1,20 мг.\u003Cbr\u003EВспомогательные вещества оболочки: гипромеллоза (гидроксипропилметилцеллюлоза) - 4,00 мг, титана диоксид - 2,90 мг, полисорбат 80 - 1,32 мг, макрогол 4000 (полиэтиленгликоль 4000) - 0,89 мг, тальк - 0,89 мг."},{"name":"Действующее вещество","value":"Мелатонин"},{"name":"Способ применения и дозы","value":"Внутрь.\u003Cbr\u003EПри нарушении сна - по 3 мг один раз в сутки за 30-40 минут до сна.\u003Cbr\u003EПри десинхронозе в качестве адаптогена при смене часовых поясов - за 1 день до перелета и в последующие 2-5 дней - по 3 мг за 30-40 минут до сна.\u003Cbr\u003EМаксимальная суточная доза - 6 мг.\u003Cbr\u003EПожилые пациенты\u003Cbr\u003EС возрастом происходит снижение метаболизма мелатонина, что необходимо учитывать при выборе режима дозирования для пожилых пациентов. С учетом этого у пациентов пожилого возраста, возможен прием препарата за 60-90 минут до сна.\u003Cbr\u003EПациентам с тяжелой почечной недостаточностью применение препарата не рекомендуется."},{"name":"Побочные действия","value":"Классификация частоты развития побочных эффектов согласно рекомендациям Всемирной Организации Здравоохранения:\u003Cbr\u003EОчень часто (≥1/10), часто (от ≥1/10 до \u003C1/10), нечасто (от ≥1/1000 до \u003C1/100), редко (от ≥1/10000 до \u003C1/1000), очень редко (\u003C1/10000), включая отдельные сообщения; частота неизвестна (по имеющимся данным установить частоту возникновения не представляется возможном).\u003Cbr\u003EИнфекционные и паразитарные заболевания:\u003Cbr\u003Eредко: опоясывающий герпес.\u003Cbr\u003EНарушения со стороны крови и лимфатической системы:\u003Cbr\u003Eредко: лейкопения, тромбоцитопения.\u003Cbr\u003EНарушения со стороны иммунной системы:\u003Cbr\u003Eчастота неизвестна: реакции гиперчувствительности.\u003Cbr\u003EНарушения со стороны обмена веществ и питания:\u003Cbr\u003Eредко: гипертриглицеридемия, гипокалиемия, гипонатриемия.\u003Cbr\u003EНарушение психики:\u003Cbr\u003Eнечасто: раздражительность, нервозность, беспокойство, бессонница, необычные сновидения, ночные кошмары, тревога;\u003Cbr\u003Eредко: перемены настроения, агрессия, ажитация, плаксивость, симптомы стресса, дезориентация, раннее утреннее пробуждение, повышение либидо, сниженное настроение, депрессия.\u003Cbr\u003EНарушения со стороны нервной системы:\u003Cbr\u003Eнечасто: мигрень, головная боль, вялость, психомоторная гиперактивность, головокружение, сонливость;\u003Cbr\u003Eредко: обморок, нарушение памяти, нарушение концентрации внимания, делирий, синдром \"беспокойных ног\", сновидное состояние, плохое качество сна, парестезии.\u003Cbr\u003EНарушения со стороны органа зрения:\u003Cbr\u003Eредко: снижение остроты зрения, нечеткость зрения, повышенное слезотечение.\u003Cbr\u003EНарушения со стороны органа слуха и лабиринтные нарушения:\u003Cbr\u003Eредко: вертиго, позиционное вертиго.\u003Cbr\u003EНарушения со стороны сердечно-сосудистой системы:\u003Cbr\u003Eнечасто: артериальная гипертензия;\u003Cbr\u003Eредко: стенокардия напряжения, ощущение сердцебиения, приливы.\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта:\u003Cbr\u003Eнечасто: абдоминальная боль, абдоминальная боль в верхней части живота, диспепсия, язвенный стоматит, сухость во рту, тошнота;\u003Cbr\u003Eредко: гастроэзофагеальная болезнь, желудочно-кишечное нарушение или расстройство, буллезный стоматит, язвенный глоссит, рвота, усиление перистальтики, вздутие живота, гиперсекреция слюны, неприятный запах изо рта, абдоминальный дискомфорт, дискинезия желудка, гастрит.\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей:\u003Cbr\u003Eнечасто: гипербилирубинемия.\u003Cbr\u003EНарушение со стороны кожи и подкожных тканей:\u003Cbr\u003Eнечасто: дерматит, потливость по ночам, зуд и генерализованный зуд, сыпь, сухость кожи;\u003Cbr\u003Eредко: экзема, эритема, дерматит рук, псориаз, генерализованная сыпь, зудящая сыпь, поражение ногтей;\u003Cbr\u003Eчастота неизвестна: отек Квинке, отек слизистой оболочки полости рта, отек языка.\u003Cbr\u003EНарушения со стороны скелетно-мышечной и соединительной ткани:\u003Cbr\u003Eнечасто: боль в конечностях.\u003Cbr\u003Eредко: артрит, мышечный спазм, боль в шее, ночные судороги.\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей:\u003Cbr\u003Eнечасто: глюкозурия, протеинурия;\u003Cbr\u003Eредко: полиурия, гематурия, никтурия.\u003Cbr\u003EНарушения со стороны половых органов и грудной железы:\u003Cbr\u003Eнечасто: менопаузальные симптомы;\u003Cbr\u003Eредко: приапизм, простатит; частота неизвестна: галакторея.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения:\u003Cbr\u003Eнечасто: астения, боль в груди;\u003Cbr\u003Eредко: утомляемость, боль, жажда.\u003Cbr\u003EЛабораторные и инструментальные данные:\u003Cbr\u003Eнечасто: отклонение от нормы лабораторных показателей функции печени, увеличение массы тела;\u003Cbr\u003Eредко: повышение активности \"печеночных\" трансаминаз, отклонение от нормы содержания электролитов в крови, отклонение от нормы результатов лабораторных тестов."},{"name":"Фармакологическое действие","value":"Мелатонин - синтетический аналог гормона шишковидного тела (эпифиза); синтезирован из аминокислот растительного происхождения.\u003Cbr\u003EОказывает адаптогенное, седативное, снотворное действие. Нормализует циркадные ритмы.\u003Cbr\u003EУвеличивает концентрацию гамма-аминомасляной кислоты (ГАМК) и серотонина в среднем мозге и гипоталамусе, изменяет активность пиридоксалькиназы, участвующей в синтезе ГАМК, дофамина и серотонина.\u003Cbr\u003EРегулирует цикл сон-бодрствование, суточные изменения локомоторной активности и температуры тела, положительно влияет на интеллектуально-мнестические функции мозга, на эмоционально-личностную сферу. Способствует организации биологического ритма и нормализации ночного сна, обладает снотворным эффектом. Улучшает качество сна, ускоряет засыпание, снижает число ночных пробуждений, улучшает самочувствие после утреннего пробуждения, не вызывает ощущение вялости, разбитости и усталости при пробуждении. Делает сновидения более яркими и эмоционально насыщенными.\u003Cbr\u003EАдаптирует организм к быстрой смене часовых поясов, снижает стрессовые реакции, регулирует нейроэндокринные функции.\u003Cbr\u003EАдаптирует организм метеочувствительных людей к изменениям погодных условий.\u003Cbr\u003EПроявляет иммуностимулирующие и антиоксидантные свойства.\u003Cbr\u003EНе вызывает привыкания и зависимости."},{"name":"Фармакологическая группа","value":"адаптогенное средство"},{"name":"Форма выпуска","value":"таблетки, покрытые пленочной оболочкой"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"При температуре не выше 25 °С, в оригинальной упаковке.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"По имеющимся литературным данным, применение мелатонина в суточной дозировке до 300 мг не вызывало клинически значимых нежелательных реакций. При приеме мелатонина в дозах от 3000 мг до 6600 мг в течение нескольких недель наблюдались такие симптомы как гиперемия, спазмы в брюшной полости, диарея, головная боль, скотома. При применении очень высоких доз мелатонина (до 1 г) наблюдалась непроизвольная потеря сознания. При передозировке возможно развитие сонливости.\u003Cbr\u003EЛечение - промывание желудка и применение активированного угля, симптоматическая терапия. Клиренс активного вещества предполагается в пределах 12 часов после приема внутрь."},{"name":"Применение при беременности и кормлении грудью","value":"Препарат противопоказан к применению при беременности и в период грудного вскармливания."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В период лечения необходимо воздержаться от управления транспортными средствами и занятий потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"С осторожностью:\u003Cbr\u003EВлияние различной степени почечной недостаточности на фармакокинетику мелатонина не изучено, поэтому таким пациентам мелатонин нужно применять с осторожностью.\u003Cbr\u003EВ период применения препарата Мелатонин Эвалар рекомендуется избегать пребывания на ярком свету.\u003Cbr\u003EНеобходимо проинформировать женщин, желающих забеременеть, о наличии у препарата слабого контрацептивного действия.\u003Cbr\u003EОтсутствуют клинические данные о применении мелатонина у больных с аутоиммунными заболеваниями, в связи с чем, применение у данной категории пациентов не рекомендуется. \u003Cbr\u003EСледует соблюдать осторожность в отношении пациентов, принимающих флувоксамин, который повышает концентрацию мелатонина за счет ингибирования его метаболизма изоферментами цитохрома Р450 (CYP): CYP1A2 и CYP2C19. Следует избегать такой комбинации.\u003Cbr\u003EСледует соблюдать осторожность в отношении пациентов, принимающих 5- и 8-метоксипсорален, который повышает концентрацию мелатонина вследствие ингибирования его метаболизма.\u003Cbr\u003EСледует соблюдать осторожность в отношении пациентов, принимающих циметидин, поскольку он повышает содержание мелатонина в плазме за счет ингибирования последнего.\u003Cbr\u003EКурение способно снизить концентрацию мелатонина за счет индукции изофермента CYP1A2.\u003Cbr\u003EСледует соблюдать осторожность в отношении пациентов, принимающих эстрогены (например, контрацептивы или заместительную гормональную терапию), которые увеличивают концентрацию мелатонина путем ингибирования их метаболизма изоферментами CYP1A1 и CYP1А2."},{"name":"Взаимодействие","value":"-Известно, что в концентрациях, значительно превышающих терапевтические, мелатонин индуцирует изофермент CYP3A in vitro. Клиническое значение этого явления до конца не выяснено. В случае развития признаков индукции следует рассмотреть вопрос о снижении дозы одновременно применяемых лекарственных средств.\u003Cbr\u003E- В концентрациях, значительно превышающих терапевтические, мелатонин не индуцирует изоферменты группы CYP1A in vitro. Следовательно, взаимодействие мелатонина с другими лекарственными средствами вследствие влияния мелатонина на изоферменты группы CYP1А, по-видимому, незначимо.\u003Cbr\u003E- Метаболизм мелатонина, главным образом, опосредован изоферментами CYP1A. Следовательно, возможно взаимодействие мелатонина с другими лекарственными средствами вследствие влияния мелатонина на изоферменты группы CYP1A.\u003Cbr\u003E- Ингибиторы изоферментов CYPA2, например, хинолоны, способны повышать экспозицию мелатонина.\u003Cbr\u003E- Индукторы изофермента CYP1A2, такие как карбамазепин и рифампицин, способны снижать плазменную концентрацию мелатонина.\u003Cbr\u003E- В современной литературе имеется множество данных, касающихся влияния агонистов/антагонистов адренергических и опиоидных рецепторов, антидепрессантов, ингибиторов простагландинов, бензодиазепинов, триптофана и алкоголя на секрецию эндогенного мелатонина. Исследования взаимного влияния этих препаратов на динамику или кинетику мелатонина не проводилось.\u003Cbr\u003EФармакодинамическое взаимодействие\u003Cbr\u003E- Во время приема мелатонина не следует употреблять алкоголь, так как он снижает эффективность препарата.\u003Cbr\u003E- Мелатонин потенцирует седативное действие бензодиазепиновых и небензодиазепиновых снотворных средств, таких как залеплон, золпидем и зопиклон. В ходе клинического исследования наблюдались четкие признаки транзиторного фармакодинамического взаимодействия между мелатонином и золпидемом спустя час после их приема. Комбинированное применение может приводить к прогрессирующему расстройству внимания, памяти и координации в сравнении с монотерапией золпидемом.\u003Cbr\u003E- В ходе исследований мелатонин назначался совместно с тиоридазином и имипрамином, препаратами, которые влияют на центральную нервную систему. Ни в одном из случаев не было выявлено клинически значимого фармакокинетического взаимодействия. Тем не менее, одновременное применение с мелатонином приводило к повышению ощущения спокойствия и к затруднениям в выполнении определенных заданий в сравнении с монотерапией имипрамином, а также к усилению чувства \"помутнения в голове\", в сравнении с монотерапией тиоридазином."},{"name":"Регистрационный номер","value":"ЛП-005295"},{"name":"Дата государственной регистрации","value":"14.01.2019"},{"name":"Владелец регистрационного удостоверения","value":"Эвалар"},{"name":"Изготовитель","value":"Эвалар"},{"name":"Фасовщик","value":"Эвалар"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Мелатонин Эвалар"},{"name":"Срок годности","value":"25 мес."}]}],"transitionId":"tr_17146560764350696057"}}}}
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Цена с картой Яндекс Пэй:318 ₽

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  • 18 июня, курьер Маркета • 249 ₽
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POLZAru
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38Котзывов
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  • Сонные+ таб., 30 шт., 1 уп.
    –33 %
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    Сонные+ таб., 30 шт., 1 уп.

    Рейтинг товара: 4.1 из 5
    на основе 149 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 269 ₽ вместо 275
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  • Формула Спокойствия Триптофан капс., 15 шт.
    –1 %
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    Формула Спокойствия Триптофан капс., 15 шт.

    Рейтинг товара: 4.6 из 5
    на основе 29 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 452 ₽ вместо 457
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  • Формула сна экспресс таб. д/рассас., 40 шт.
    –1 %
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    Формула сна экспресс таб. д/рассас., 40 шт.

    Рейтинг товара: 3.7 из 5
    на основе 3 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 483 ₽ вместо 488
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  • Реасон Мелатонин капс., 2 мг, 60 шт., 1 уп.
    –1 %
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    Реасон Мелатонин капс., 2 мг, 60 шт., 1 уп.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    С картой  Пэй
    Цена с картой Яндекс Пэй 772 ₽ вместо 780
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  • Гинкго Билоба Эвалар таб., 0.5 г, 100 шт., 1 уп.
    –11 %
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    Гинкго Билоба Эвалар таб., 0.5 г, 100 шт., 1 уп.

    Рейтинг товара: 4.6 из 5
    на основе 7 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 1 296 ₽ вместо 1 309
    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Билоба Эвалар таб., 0.5 г, 100 шт., 1 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  • Формула сна усиленная фито-мелатонином капс., 30 шт.
    –1 %
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    Формула сна усиленная фито-мелатонином капс., 30 шт.

    Рейтинг товара: 4 из 5
    на основе 11 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 613 ₽ вместо 619
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  • GLS Триптофан капс., 500 мг, 0.25 г, 90 шт.
    –10 %
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    GLS Триптофан капс., 500 мг, 0.25 г, 90 шт.

    Рейтинг товара: 4.8 из 5
    на основе 24 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 540 ₽ вместо 550
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Триптофан капс., 500 мг, 0.25 г, 90 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  • Good Sleep спрей фл., 30 мл, 10 г, 1 шт., мятный, 1 уп.
    –34 %
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    Good Sleep спрей фл., 30 мл, 10 г, 1 шт., мятный, 1 уп.

    Рейтинг товара: 4.6 из 5
    на основе 223 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 1 185 ₽ вместо 1 209
    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Sleep спрей фл., 30 мл, 10 г, 1 шт., мятный, 1 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  • Формула сна таб., 40 шт., 1 уп.
    –1 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-s3540qu90x/toggleWishlist":{"skuId":"101826746755","productId":265154706,"offerId":"6iMLtFvWYt_I5w6OMptjCQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ/5nK6qPYve0SEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYIkuG3fhCDs+Oq+wIY1buhBiDt2cEH","sign":"yr/k8OC5D6fvQ1zIqvqJ8keuVMIe9jLNT6jqea4rvtY="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-s3540qu90x/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Формула сна таб., 40 шт., 1 уп.

    Рейтинг товара: 4.2 из 5
    на основе 21 оценка
    С картой  Пэй
    Цена с картой Яндекс Пэй 409 ₽ вместо 413
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  • Релаксозан День таб., 40 шт.
    –2 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-2p3h3l418o6/toggleWishlist":{"skuId":"662913030","productId":1404748725,"offerId":"vlofFuboBG9cplvDff8e6w","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ/5nK6qPYve0SEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYItYfrnQUQhoCNvAIY1buhBiDt2cEH","sign":"CcHbH2SfN1gkmML8O81crR+LTPY6ymMjSYIng0rFUbA="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-2p3h3l418o6/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Релаксозан День таб., 40 шт.

    Рейтинг товара: 4.7 из 5
    на основе 124 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 669 ₽ вместо 683
    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День таб., 40 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  • Natrol Melatonin таб., 3 мг, 100 г, 60 шт.
    –28 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-zx1ybtqq24e/toggleWishlist":{"skuId":"101488341730","productId":1467295415,"offerId":"WQKD1LRMa62ac5YWsxSEiw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ/5nK6qPYve0SEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIt83UuwUQ4uW0ifoCGNau7BEg7dnBBw==","sign":"6Epg41H6sdWWItAHc0NJJ8Uuz3ucShkP79GbP6DYxXI="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-zx1ybtqq24e/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Natrol Melatonin таб., 3 мг, 100 г, 60 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    С картой  Пэй
    Цена с картой Яндекс Пэй 1 558 ₽ вместо 1 590
    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Melatonin таб., 3 мг, 100 г, 60 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Инструкция

Показания к применению

При расстройствах сна, в т.ч. обусловленных нарушением ритма "сон-бодрствование", таких как десинхроноз (резкая смена часовых поясов).

Противопоказания

Гиперчувствительность к компонентам препарата, аутоиммунные заболевания, печеночная недостаточность, тяжелая почечная недостаточность, детский возраст до 18 лет, беременность, период грудного вскармливания.

Способ применения и дозы

Внутрь.
При нарушении сна - по 3 мг один раз в сутки за 30-40 минут до сна.
При десинхронозе в качестве адаптогена при смене часовых поясов - за 1 день до перелета и в последующие 2-5 дней - по 3 мг за 30-40 минут до сна.
Максимальная суточная доза - 6 мг.
Пожилые пациенты
С возрастом происходит снижение метаболизма мелатонина, что необходимо учитывать при выборе режима дозирования для пожилых пациентов. С учетом этого у пациентов пожилого возраста, возможен прием препарата за 60-90 минут до сна.
Пациентам с тяжелой почечной недостаточностью применение препарата не рекомендуется.
Полная инструкция
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Мелатонин Эвалар таб. п/о плен.
Мелатонин Эвалар таб. п/о плен., 3 мг, 20 шт., 1 уп.
4.4
(148)
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13 вопросов
Инструкция

Цена с картой Яндекс Пэй:318 ₽

Скидка: 1%
–1 %
Вместо: 321 ₽
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4.4
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У продавца:148 оценок·49 отзывов
У всех продавцов:710 оценок·295 отзывов
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user avatar
Год назад • Анна Ивановна • Куплен на Маркете
Достоинства: Отличный препарат. Работает хорошо. Засыпаю после приëма мелатонина минут через 40-50. Если ночью просыпаюсь, то тут же снова засыпаю. Утром пробуждение без проблем, никакой сонливости.
Недостатки: не обнаружила
Комментарий: Рекомендую к покупке тем, у кого есть проблемы со сном, особенно когда пробуждение среди ночи, а потом долго не уснуть.
user avatar
2 года назад • Гульзат Абабакирова • Куплен на Маркете
Достоинства: Помогает
user avatar
7 месяцев назад • Влад Кшнякин • Куплен на Маркете
Комментарий: Хорошие таблетки для улучшения сна, периодически пользуюсь при нарушении режима, очень помогают (это не снотворное, а натуральный гормон сна)
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    Цена 26 ₽
  • Гармония сна капс., 0.36 г
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    Гармония сна капс., 0.36 г

    Цена 311 ₽ вместо 742
  • Формула сна экспресс таб. д/рассас., 40 шт.
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    Формула сна экспресс таб. д/рассас., 40 шт.

    Цена 483 ₽ вместо 488
  • Реасон Мелатонин капс., 2 мг, 60 шт., 1 уп.
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    Реасон Мелатонин капс., 2 мг, 60 шт., 1 уп.

    Цена 772 ₽ вместо 780
  • Мезим Форте таб. п/о, 20 шт.
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    Мезим Форте таб. п/о, 20 шт.

    Цена 103 ₽ вместо 105
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    Реклама
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    {"widgets":{"@marketfront/CreativeBanner":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_101_8/content/content/content":{"cpcLink":"/safeclick/data=SpQw45JhDGEtO5qMksCMdB2XABugBWM0Asx0Ut01ixXX-FhTZgV03elAvWI0GbQJfgn6gCWhX8wgxtIVuhyiYsDtkU4BdwX6VEq8eXpK-UdqiItr9jWjuPLq1vIZkzumGPfRlTA2iKm-VGhUKeVO2id2YHQ7rOML280B9ikjDBT6mRGbG2PvsXt910gMts_jQJLIh8KBKy0oJlxh-s7SkO5AEmZWztsvfI0nCxw6T7i1n0yhc0jJWdVTlL1cwzONmLnyMnvyzAFl5LbIjNo7YvKPVDraayDxu2Z9YrYhvKX3i2mKvLU88GI-gvsGq6JrOArI4EwMeywki8WIdS8uQ5kNYcHJCX2bcp_XDOyB2FSlDjWnEVp4oLH8_fwWE6ulkwW8eV9rfI6n78zuJTZytIBbSNjrd58pWxZpopZodMqpLcL9P4wiW9fdz8hMSme-qhy95fLPR0W7koVIehVO5E2ra34o2_NX_9lWF32dJHppB0XsZ0XOmNH9n_V88hNGEVf1uii2hJT1r-bXY2koYrDz04TDbtICqakH1uMgpM1MPWljvx0VrwsNxOBg-ecruUDYkngzidrd9juv8pYU7y-5SFRMJ-dKSFXf6P061ywfsADJFdBU6iL3VN-MGVr9VNiU-kWuvRJTEgPGzH7_8WJzPs05F-ff30Z5M4bLZC-cen7GUwD4tGNeCV7MXcZK93aXxmabrPUIjJYgk1XSrU9ePZ-FN8yrQUG46A0kfu22iUe158wDCAJ_3UezQE9MiwW8YUPEzoCYWEAlh-8V2caPLoyWXH27AZHttz9pyuIKkUloqJ959CoDYcDom3T6kaSHkeXFlqo0LMAyffkvvhOVThIM4tpFyW1STLwAIOYYAiat5T6ZM2U22z-EkRWyJ3qplzsBoTVkOSL4oPR7BYNgnEl1bmUTF4h7GwCdQmseE2rfzMQmcsre6YS-3W58eyznCC8XCjw9sDrS0ikc0tnryB448x-7llEibzjRjYBMWXACAjoUL-sfQbYVWsD_yg0AMExz4F9DAVVbU4SgxSpr88s3rQD8QyORZ15_vnDMPDFWSMxgol7_aKy5dj8x7Rjqebkxp1NWsYTn-jilwU9PCFKBF-qYtcD_vW4Tdgan_qcPL3AKzjm5wFFVh0gvMMGXqH3nClicnfRqMYRpTJAiQ00xdxu86XMnVkCQXvL3VRkPY_fekXBaxhtrhTUzn8vsZoNlcQXXoP4rgCZ9CX8q--nYhcULD39crT3HVJ2jLMCR871iyJmvGuSefLIgKTr2OnU8GgbQxNImZuN9SxPiB9KjQjsKcIBRhqvgq3vLeEaRI5fxq6U1lSSQd_v3jABSvy-2mHhN_2vjsAdci5xtCECVecvyi_HY-95LinOKT2UdsdR0o_lWr-TRk_U95GO6E9TNBnfozfYM9__FCP8aguSgeQzWa07ZXPqqfWsE2tSPeG44kb0sPezqFK7M5ZNUGhWR7QB7oyWA9HCNJUjXTB6bdvsC4z4ONsP_2sVZhReRGgmKxXaY7ALzDU_Ghu0IZFRbD0U-lNG0km45J831dP5DpjEJjO7fgTWjWEeHpcVnrwO2WzzVfBHZNyN1hXWj-51qxctHLpOMnQyzUh5Z4PwzZOq0AMs_Qb7ipilFFuRFNHoi3E_RA2Dv-qRMBpIK9cqDkyeGVal_HGhPGiakKmEYZzdbLz5AtCeawylynkLfFZUp4T6EfORA7c9MI2MDgrljZoo4fB9bm9X5FDm6vRh81ITKccy_lO0L1NRbBnzdRM5_BKJUGje2inIj_4PD0DdV-de-EO58tA0svfTGlUTu7DUW9M3eiBIT0jOimcJ39zA_pWlZ3VmqStQMjME79Ay5FZgHyXt8MRDwUXYZ0ynJrgRcr996Ix69A4fjIA_R1vdEI9BAOlByUYyy_3sfNHD1CSD1LH5_CbtzRjdcbKaeljP60b64CvENfoTVGV__38Y1-SojZl9lt7v0IMuIqZr2MLvp-0lmhg7B3LXt3YDf7tlgyWmE7OW1zrD4gajTPVH1P-EpLUaMRp0b2HUj9Edec0a1fsGZkxr5xehN5MD5OZNznvMp-V6f9bP7Eoscm19brRp_wU1208vrEvFsOMdqbQQOcJKjADw8KbDH8nmdctzqRF4Xsb48nsY__lExIkBkVujyDiyNplFUzHPp2LtxlJ8ytMy91p6LA-MSpPEutXkTzMbhZc96W8hpQMUKOrNam5H4yHhTgBLtFDfABxBl_TTb9_b4bj0r3gxY61oSD3wvT8Kyp5zNaZAwmnSj1BLoy8lMD09My19dSEySNQjY8br_mJs0jOoQZwyM2Mz7rFPP5pYZyBupKU7sT3ok7P7cW0pxmDmUNaUbrKFnCTX7HGXsY79aqnsakgBCbil7TZBFdkoyh8V1jabuzdFVUXKJuFvwetKv4T1ENXGaF8OHzEx5qymq6W1V7yvkLPSk696U6C5PerXhdpoO2KuG777YTR7ZOqvsJ4ZakaaxaFKLwudItQla6v3MWFJ3Is2AHX0mLlah2_rn7T88dKrqRxRvXxKN9HfqFjOtsQ8Pp7NxUqc7HC2OEhnzpntM8apoIiwkahbJA0_NBe53a6wJCWRYzX6xj3627-L8xmrMKHgdzpEFuysvUQPx5g0k7oUNWvvIDro0VnRKyTrCKIrcAiZAymW2DbfgzA1J3pWRwDFsxhQ,/b64e=1/sign=de7fcf3d778ca05701af11ba41298777/keyno=MARKET_1/*","url":"https://market.yandex.ru/special/climat_p?fromSins=1&erid=nyi26TK8Sq2EHejwvAGD5zK7xRB9wp1B","isClickoutExternal":true,"src":"https://avatars.mds.yandex.net/get-market-adv/8282799/70d4b367-6050-42a5-af59-be1e2422f4c6/470x762","srcSet":"https://avatars.mds.yandex.net/get-market-adv/8282799/70d4b367-6050-42a5-af59-be1e2422f4c6/470x762 1x, https://avatars.mds.yandex.net/get-market-adv/8282799/70d4b367-6050-42a5-af59-be1e2422f4c6/940x1524 2x","showUrl":"/safeclick/data=SpQw45JhDGE6zDtOdUQO_FineRVm_EmrfeCl3rCGV-IAqwfcQFv2DQHGLGupIjgKEhWLOhPFd4l4V6nD8T7fMWY45rUeziCM_Sw-7XLWfGK0g0_HSp4gbLKHX5tiaWlcYPzjEWRSOhp8_NwuDEROYhAJZ7wbk9QqlzQbo6bNW4P6vwPLGht2OwYwTQu-XjdlHjSBSTF_ZgWH9bN89XgoUAC5FGgbYgO4yPAkRXFi7ffVisWDhKfKDwrMG59pFNNyEH0A6u9BhqAPDjd6l3KtWByMIkj2lFJKBsjANuKAFEKJu3ol8XkOV2PogNjf5qjO03SY53nqyv-WzpywgkqVpn6m0BPc1c0KPZfSotoFOW10csPkGBLp_g1cQbin0cjS6JT7JPxLO0G-nK-uReg9ymKV2RPS8MFlln_vjHYV41Y9LrPIGSVjj4T79wduTk9be5X0ta_BD1npVJbd972rGn98qubfOhw4eYYlFB2NhdI3wzfRCh35_orjD566_pVfA7aK9DdwjGQB7mrkrtAZXvbXlKvIgyTa3yH__la8ndtPNabKOGiPlhFybgBbNOfZC20a7JW4wp4OwvLkUVIBzwa0pj3OPL9B1Ufgs-9EKdzWy6dneYDwUpADR12Vf2QkCgQ6FL2j7XKo7Ok351CmvS9Fnyf8pIVt50VICqo6d-HXNXMGinUtQVEG-TTRIpShieUxllsOcxD0lBKWk4qNtn4vrdVcBrkcmMX2pn52FupLz_diWMnbDIJK5B1L5lZKUt1OJuZ9mc5dC1iWsUep2k6SmDfpSuqmoYziHSGPCrhZ_8M0TLPbVUEPHNdgDAqCi6Dpnuge308QCfQArU-0WA5F2iTeoOjH1h812rppB9xR_jLliDjfBvOUX9MYORHqIE_uD7W9_1_TyGiXOs3iSesorcKpJg7HXFVOIn5QhKjVi6FFUgEo7PypqsQnL9LvUWrU7DPqi2qh-DTgarw_7XSZegLEfbni43OvnJBUMXxvF35CAZZm1Ngu_VCM6iUiGpYk6AK26H4iWk8tigHMJVpYMdm_qpR8A51CR14qbQM9_iQNDZMrXto1LnNBHX-wBRNe73uewshi5E5OEOEc3g,,/b64e=1/sign=33cf69465802f576b8fc60551d5db3aa/keyno=MARKET_1/*","roundedCorners":true,"advertisementId":1867121,"fixedRatio":false,"height":762,"width":470,"billingTargetId":"hppvzyykewm_1867121","creativeType":"Banner","position":8,"isWhole":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_101_8/content/content/content":{"name":"@marketfront/CreativeBanner"}}}
  • Витамин Д3 + К2 таб. жев., 1200 МЕ, 0.22 г, 60 шт.
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    Витамин Д3 + К2 таб. жев., 1200 МЕ, 0.22 г, 60 шт.

    Цена 408 ₽ вместо 412
  • Сонные+ таб., 30 шт., 1 уп.
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    Сонные+ таб., 30 шт., 1 уп.

    Цена 269 ₽ вместо 399
  • Эрмиталь капc. кш/раств., 10000 ЕД, 20 шт.
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    Эрмиталь капc. кш/раств., 10000 ЕД, 20 шт.

    Цена 207 ₽ вместо 209
  • Магний В6 таб., 1.25 г, 60 шт.
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    Магний В6 таб., 1.25 г, 60 шт.

    Цена 382 ₽ вместо 407
  • Снуп спрей наз., 90 мкг/доза, 15 мл
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    Снуп спрей наз., 90 мкг/доза, 15 мл

    Цена 139 ₽ вместо 154
  • Полисорб МП пор. д/приг. сусп. д/вн. приема, 12 г
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    Полисорб МП пор. д/приг. сусп. д/вн. приема, 12 г

    Цена 274 ₽ вместо 277
  • Формула сна усиленная фито-мелатонином капс., 30 шт.
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    Формула сна усиленная фито-мелатонином капс., 30 шт.

    Цена 613 ₽ вместо 619
  • Хлоргексидина биглюконат р-р д/мест. и нар. прим. фл., 0,05%, 100 мл
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    Хлоргексидина биглюконат р-р д/мест. и нар. прим. фл., 0,05%, 100 мл

    Цена 17 ₽
  • Формула сна таб., 40 шт., 1 уп.
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    Формула сна таб., 40 шт., 1 уп.

    Цена 409 ₽ вместо 413
  • GLS Триптофан капс., 500 мг, 0.25 г, 90 шт.
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    GLS Триптофан капс., 500 мг, 0.25 г, 90 шт.

    Цена 540 ₽ вместо 600
  • Гинкго Билоба Эвалар таб., 0.5 г, 40 шт., 1 уп.
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    Гинкго Билоба Эвалар таб., 0.5 г, 40 шт., 1 уп.

    Цена 428 ₽ вместо 432
  • Релаксозан День таб., 20 шт.
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    Релаксозан День таб., 20 шт.

    Цена 488 ₽ вместо 493
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    Реклама
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  • Natrol Melatonin таб., 3 мг, 100 г, 60 шт.
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    Natrol Melatonin таб., 3 мг, 100 г, 60 шт.

    Цена 1 558 ₽ вместо 2 150
  • Панкреатин таб. п/о кш/раств. (блистеры), 25 ЕД, 20 шт.
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    Панкреатин таб. п/о кш/раств. (блистеры), 25 ЕД, 20 шт.

    Цена 35 ₽
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