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Описание

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Мелатонин-СЗ таб. п/о плен., 3 мг, 60 шт., 1 уп.

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4.8
(71)
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Количество штук в упаковке, шт.: 60

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Коротко о товаре

Артикул Маркета
3301168696
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
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карбоксиметилкрахмал натрия - 6,5 мг; кальция гидрофосфата дигидрат - 41,0 мг; магния стеарат - 1,0 мг\u003Cbr\u003Eсостав оболочки: гипромеллоза - 1,53 мг; полисорбат-80 (твин-80) - 0,64 мг; тальк - 0,51 мг; титана диоксид Е 171 - 0,32 мг."},{"name":"Действующее вещество","value":"Мелатонин","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["27144131:28708746"]}}},{"name":"Способ применения и дозы","value":"Внутрь.\u003Cbr\u003EПри нарушении сна - по 3 мг один раз в сутки за 30-40 минут до сна.\u003Cbr\u003EПри десинхронозе в качестве адаптогена при смене часовых поясов - за 1 день до перелета и в последующие 2-5 дней - по 3 мг за 30-40 минут до сна.\u003Cbr\u003EМаксимальная суточная доза - 6 мг.\u003Cbr\u003EПожилые пациенты\u003Cbr\u003EС возрастом происходит снижение метаболизма мелатонина, что необходимо учитывать при выборе режима дозирования для пожилых пациентов.\u003Cbr\u003EС учетом этого у пациентов пожилого возраста, возможен прием препарата за 60-90 минут до сна.\u003Cbr\u003EПациентам с тяжелой почечной недостаточностью применение препарата не рекомендуется."},{"name":"Побочные действия","value":"Классификация частоты развития побочных эффектов согласно рекомендациям Всемирной Организации Здравоохранения: очень часто (≥1/10), часто (от ≥1/100 до \u003C1/10), нечасто (от ≥1/1000 до \u003C1/100), редко (от ≥1/10000 до \u003C1/1000), очень редко (\u003C 1/10000), включая отдельные сообщения; частота неизвестна (по имеющимся данным установить частоту возникновения не представляется возможным).\u003Cbr\u003EИнфекционные и паразитарные заболевания:\u003Cbr\u003Eредко: опоясывающий герпес.\u003Cbr\u003EНарушения со стороны крови и лимфатической системы:\u003Cbr\u003Eредко: лейкопения, тромбоцитопения.\u003Cbr\u003EНарушения со стороны иммунной системы:\u003Cbr\u003Eчастота неизвестна: реакции гиперчувствительности.\u003Cbr\u003EНарушения со стороны обмена веществ и питания:\u003Cbr\u003Eредко: гипертриглицеридемия, гипокалиемия, гипонатриемия.\u003Cbr\u003EНарушения психики:\u003Cbr\u003Eнечасто: раздражительность, нервозность, беспокойство, бессонница, необычные сновидения, ночные кошмары, тревога;\u003Cbr\u003Eредко: перемены настроения, агрессия, ажитация, плаксивость, симптомы стресса, дезориентация, раннее утреннее пробуждение, повышение либидо, сниженное настроение, депрессия.\u003Cbr\u003EНарушения со стороны нервной системы:\u003Cbr\u003Eнечасто: мигрень, головная боль, вялость, психомоторная гиперактивность, головокружение, сонливость;\u003Cbr\u003Eредко: обморок, нарушение памяти, нарушение концентрации внимания, делирий, синдром \"беспокойных ног\", плохое качество сна, парестезии.\u003Cbr\u003EНарушения со стороны органа зрения:\u003Cbr\u003Eредко: снижение остроты зрения, нечеткость зрения, повышенное слезотечение.\u003Cbr\u003EНарушения со стороны органа слуха и лабиринтные нарушения:\u003Cbr\u003Eредко: вертиго, позиционное вертиго.\u003Cbr\u003EНарушения со стороны сердечно-сосудистой системы:\u003Cbr\u003Eнечасто: артериальная гипертензия;\u003Cbr\u003Eредко: стенокардия напряжения, ощущение сердцебиения, приливы.\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта:\u003Cbr\u003Eнечасто: абдоминальная боль, абдоминальная боль в верхней части живота, диспепсия, язвенный стоматит, сухость во рту, тошнота;\u003Cbr\u003Eредко: гастроэзофагеальная болезнь, желудочно-кишечное нарушение или расстройство, буллезный стоматит, язвенный глоссит, рвота, усиление перистальтики, вздутие живота, гиперсекреция слюны, неприятный запах изо рта, абдоминальный дискомфорт, дискинезия желудка, гастрит.\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей:\u003Cbr\u003Eнечасто: гипербилирубинемия.\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей:\u003Cbr\u003Eнечасто: дерматит, потливость по ночам, зуд и генерализованный зуд, сыпь, сухость кожи;\u003Cbr\u003Eредко: экзема, эритема, дерматит рук, псориаз, генерализованная сыпь, зудящая сыпь, поражение ногтей;\u003Cbr\u003Eчастота неизвестна: отек Квинке, отек слизистой оболочки полости рта, отек языка.\u003Cbr\u003EНарушения со стороны скелетно-мышечной и соединительной ткани:\u003Cbr\u003Eнечасто: боль в конечностях;\u003Cbr\u003Eредко: артрит, мышечный спазм, боль в шее, ночные судороги.\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей:\u003Cbr\u003Eнечасто: глюкозурия, протеинурия;\u003Cbr\u003Eредко: полиурия, гематурия, никтурия.\u003Cbr\u003EНарушения со стороны половых органов и грудной железы:\u003Cbr\u003Eнечасто: менопаузальные симптомы; редко: приапизм, простатит;\u003Cbr\u003Eчастота неизвестна: галакторея.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения:\u003Cbr\u003Eнечасто: астения, боль в груди;\u003Cbr\u003Eредко: утомляемость, боль, жажда."},{"name":"Фармакологическое действие","value":"Синтетический аналог гормона шишковидного тела (эпифиза); оказывает адаптогенное, седативное, снотворное действие. Нормализует циркадные ритмы. Увеличивает концентрацию гамма-аминомасляной кислоты (ГАМК) и серотонина в среднем мозге и гипоталамусе, изменяет активность пиридоксалькиназы, участвующей в синтезе ГАМК, дофамина и серотонина. Регулирует цикл сон-бодрствование, суточные изменения локомоторной активности и температуры тела, положительно влияет на интеллектуально-мнестические функции мозга, на эмоционально-личностную сферу. Способствует организации биологического ритма и нормализации ночного сна. Улучшает качество сна, ускоряет засыпание, регулирует нейроэндокринные функции. Адаптирует организм метеочувствительных людей к изменениям погодных условий."},{"name":"Фармакологическая группа","value":"адаптогенное средство"},{"name":"Форма выпуска","value":"таблетки, покрытые пленочной оболочкой"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"В защищенном от света месте, при температуре не выше 25 °С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"По имеющимся литературным данным, применение мелатонина в суточной дозе до 300 мг не вызывало клинически значимых нежелательных реакций. Наблюдались гиперемия, спазмы в брюшной полости, диарея, головная боль и скотома при применении мелатонина в дозах 3000-6600 мг в течение нескольких недель. При применении очень высоких доз мелатонина (до 1 г) наблюдалась непроизвольная потеря сознания.\u003Cbr\u003EПри передозировке возможно развитие сонливости.\u003Cbr\u003EЛечение - промывание желудка и применение активированного угля, симптоматическая терапия.\u003Cbr\u003EКлиренс активного вещества предполагается в пределах 12 часов после приема внутрь."},{"name":"Применение при беременности и кормлении грудью","value":"Препарат противопоказан к применению при беременности и в период грудного вскармливания."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Препарат Мелатонин-СЗ вызывает сонливость, в связи с этим в период лечения следует воздержаться от вождения автотранспорта и занятий потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"В период применения препарата Мелатонин-СЗ рекомендуется избегать пребывания на ярком свету.\u003Cbr\u003EНеобходимо проинформировать женщин, желающих забеременеть, о наличии у препарата слабого контрацептивного действия.\u003Cbr\u003EОтсутствуют клинические данные о применении мелатонина у больных с аутоиммунными заболеваниями, в связи с чем применение у данной категории пациентов не рекомендуется.\u003Cbr\u003EС осторожностью:\u003Cbr\u003EПрепарат Мелатонин-СЗ нужно применять с осторожностью пациентам с различной степенью почечной недостаточности.\u003Cbr\u003EСледует соблюдать осторожность в отношении пациентов, принимающих флувоксамин, который повышает концентрацию мелатонина за счет ингибирования его метаболизма изоферментами цитохрома Р450 (CYP): CYP1A2 и CYP2C19. Следует избегать такой комбинации.\u003Cbr\u003E Следует соблюдать осторожность в отношении пациентов, принимающих 5- и 8-метоксипсорален, который повышает концентрацию мелатонина вследствие ингибирования его метаболизма.\u003Cbr\u003EСледует соблюдать осторожность в отношении пациентов, принимающих циметидин, поскольку он повышает содержание мелатонина в плазме за счет ингибирования последнего.\u003Cbr\u003EСледует соблюдать осторожность в отношении пациентов, принимающих эстрогены (например, контрацептивы или заместительную гормональную терапию), которые увеличивают концентрацию мелатонина путем ингибирования их метаболизма изоферментами CYP1А1 и CYP1A2."},{"name":"Взаимодействие","value":"Фармакокинетическое взаимодействие\u003Cbr\u003E- Известно, что в концентрациях, значительно превышающих терапевтические, мелатонин индуцирует изофермент CYP3A in vitro. Клиническое значение этого явления до конца не выяснено. В случае развития признаков индукции следует рассмотреть вопрос о снижении дозы одновременно применяемых лекарственных средств.\u003Cbr\u003E- В концентрациях, значительно превышающих терапевтические, мелатонин не индуцирует изоферменты группы CYP1A in vitro. Следовательно, взаимодействие мелатонина с другими лекарственными средствами вследствие влияния мелатонина на изоферменты группы CYP1A, по-видимому, незначимо.\u003Cbr\u003E- Метаболизм мелатонина, главным образом, опосредован изоферментами CYP1A. Следовательно, возможно взаимодействие мелатонина с другими лекарственными средствами вследствие влияния мелатонина на изоферменты группы CYP1 А.\u003Cbr\u003E-Курение способно снизить концентрацию мелатонина за счет индукции изофермента CYP1A2.\u003Cbr\u003E- Ингибиторы изоферментов CYPA2, например, хинолоны, способны повышать экспозицию мелатонина.\u003Cbr\u003E- Индукторы изофермента CYP1A2, такие как карбамазепин и рифампицин, способны снижать плазменную концентрацию мелатонина.\u003Cbr\u003E- В современной литературе имеется множество данных, касающихся влияния агонистов/антагонистов адренергических и опиоидных рецепторов, антидепрессантов, ингибиторов простагландинов, бензодиазепинов, триптофана и алкоголя на секрецию эндогенного мелатонина. Исследования взаимного влияния этих препаратов на динамику или кинетику мелатонина не проводилось.\u003Cbr\u003EФармакодинамическое взаимодействие\u003Cbr\u003E- Во время приема мелатонина не следует употреблять алкоголь, так как он снижает эффективность препарата.\u003Cbr\u003E- Мелатонин потенцирует седативное действие бензодиазепиновых и небензодиазепиновых снотворных средств, таких как залеплон, золпидем и зопиклон. В ходе клинического исследования наблюдались четкие признаки транзиторного фармакодинамического взаимодействия между мелатонином и золпидемом спустя час после их приема. Комбинированное применение может приводить к прогрессирующему расстройству внимания, памяти и координации в сравнении с монотерапией золпидемом.\u003Cbr\u003E- В ходе исследований мелатонин назначался совместно с тиоридазином и имипрамином, препаратами, которые влияют па центральную нервную систему. Ни в одном из случаев не было выявлено клинически значимого фармакокинетического взаимодействия. Тем не менее, одновременное применение с мелатонином приводило к повышению ощущения спокойствия и к затруднениям в выполнении определенных заданий в сравнении с монотерапией имипрамином, а также к усилению чувства \"помутнения в голове\", в сравнении с монотерапией тиоридазином."},{"name":"Регистрационный номер","value":"ЛП-004758"},{"name":"Дата государственной регистрации","value":"13.05.2019"},{"name":"Владелец регистрационного удостоверения","value":"Северная Звезда","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["34324371:35649313","7893318:16002862"]}}},{"name":"Изготовитель","value":"Северная Звезда"},{"name":"Фасовщик","value":"Северная Звезда"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Мелатонин-СЗ","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["17796364:18023779"]}}},{"name":"Срок годности","value":"36 мес."}]}},"fullSpecsGrouped":{"13035041238721412416":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Органы и системы","value":"нервная система"},{"name":"Назначение","value":"бессонница, десинхроноз, нарушение сна"},{"name":"Показания к применению","value":"При расстройстве сна, в т.ч. обусловленных нарушением ритма \"сон- бодрствование\", таких как десинхроноз (резкая смена часовых поясов)."},{"name":"Противопоказания","value":"Гиперчувствительность к компонентам препарата, аутоиммунные заболевания, печеночная недостаточность, тяжелая почечная недостаточность, беременность, период грудного вскармливания, детский возраст до 18 лет."},{"name":"Состав","value":"1 таблетка содержит:\u003Cbr\u003Eдействующее вещество: мелатонин - 3 мг\u003Cbr\u003Eвспомогательные вещества: целлюлоза микрокристаллическая 102 - 48,5 мг; карбоксиметилкрахмал натрия - 6,5 мг; кальция гидрофосфата дигидрат - 41,0 мг; магния стеарат - 1,0 мг\u003Cbr\u003Eсостав оболочки: гипромеллоза - 1,53 мг; полисорбат-80 (твин-80) - 0,64 мг; тальк - 0,51 мг; титана диоксид Е 171 - 0,32 мг."},{"name":"Действующее вещество","value":"Мелатонин"},{"name":"Способ применения и дозы","value":"Внутрь.\u003Cbr\u003EПри нарушении сна - по 3 мг один раз в сутки за 30-40 минут до сна.\u003Cbr\u003EПри десинхронозе в качестве адаптогена при смене часовых поясов - за 1 день до перелета и в последующие 2-5 дней - по 3 мг за 30-40 минут до сна.\u003Cbr\u003EМаксимальная суточная доза - 6 мг.\u003Cbr\u003EПожилые пациенты\u003Cbr\u003EС возрастом происходит снижение метаболизма мелатонина, что необходимо учитывать при выборе режима дозирования для пожилых пациентов.\u003Cbr\u003EС учетом этого у пациентов пожилого возраста, возможен прием препарата за 60-90 минут до сна.\u003Cbr\u003EПациентам с тяжелой почечной недостаточностью применение препарата не рекомендуется."},{"name":"Побочные действия","value":"Классификация частоты развития побочных эффектов согласно рекомендациям Всемирной Организации Здравоохранения: очень часто (≥1/10), часто (от ≥1/100 до \u003C1/10), нечасто (от ≥1/1000 до \u003C1/100), редко (от ≥1/10000 до \u003C1/1000), очень редко (\u003C 1/10000), включая отдельные сообщения; частота неизвестна (по имеющимся данным установить частоту возникновения не представляется возможным).\u003Cbr\u003EИнфекционные и паразитарные заболевания:\u003Cbr\u003Eредко: опоясывающий герпес.\u003Cbr\u003EНарушения со стороны крови и лимфатической системы:\u003Cbr\u003Eредко: лейкопения, тромбоцитопения.\u003Cbr\u003EНарушения со стороны иммунной системы:\u003Cbr\u003Eчастота неизвестна: реакции гиперчувствительности.\u003Cbr\u003EНарушения со стороны обмена веществ и питания:\u003Cbr\u003Eредко: гипертриглицеридемия, гипокалиемия, гипонатриемия.\u003Cbr\u003EНарушения психики:\u003Cbr\u003Eнечасто: раздражительность, нервозность, беспокойство, бессонница, необычные сновидения, ночные кошмары, тревога;\u003Cbr\u003Eредко: перемены настроения, агрессия, ажитация, плаксивость, симптомы стресса, дезориентация, раннее утреннее пробуждение, повышение либидо, сниженное настроение, депрессия.\u003Cbr\u003EНарушения со стороны нервной системы:\u003Cbr\u003Eнечасто: мигрень, головная боль, вялость, психомоторная гиперактивность, головокружение, сонливость;\u003Cbr\u003Eредко: обморок, нарушение памяти, нарушение концентрации внимания, делирий, синдром \"беспокойных ног\", плохое качество сна, парестезии.\u003Cbr\u003EНарушения со стороны органа зрения:\u003Cbr\u003Eредко: снижение остроты зрения, нечеткость зрения, повышенное слезотечение.\u003Cbr\u003EНарушения со стороны органа слуха и лабиринтные нарушения:\u003Cbr\u003Eредко: вертиго, позиционное вертиго.\u003Cbr\u003EНарушения со стороны сердечно-сосудистой системы:\u003Cbr\u003Eнечасто: артериальная гипертензия;\u003Cbr\u003Eредко: стенокардия напряжения, ощущение сердцебиения, приливы.\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта:\u003Cbr\u003Eнечасто: абдоминальная боль, абдоминальная боль в верхней части живота, диспепсия, язвенный стоматит, сухость во рту, тошнота;\u003Cbr\u003Eредко: гастроэзофагеальная болезнь, желудочно-кишечное нарушение или расстройство, буллезный стоматит, язвенный глоссит, рвота, усиление перистальтики, вздутие живота, гиперсекреция слюны, неприятный запах изо рта, абдоминальный дискомфорт, дискинезия желудка, гастрит.\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей:\u003Cbr\u003Eнечасто: гипербилирубинемия.\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей:\u003Cbr\u003Eнечасто: дерматит, потливость по ночам, зуд и генерализованный зуд, сыпь, сухость кожи;\u003Cbr\u003Eредко: экзема, эритема, дерматит рук, псориаз, генерализованная сыпь, зудящая сыпь, поражение ногтей;\u003Cbr\u003Eчастота неизвестна: отек Квинке, отек слизистой оболочки полости рта, отек языка.\u003Cbr\u003EНарушения со стороны скелетно-мышечной и соединительной ткани:\u003Cbr\u003Eнечасто: боль в конечностях;\u003Cbr\u003Eредко: артрит, мышечный спазм, боль в шее, ночные судороги.\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей:\u003Cbr\u003Eнечасто: глюкозурия, протеинурия;\u003Cbr\u003Eредко: полиурия, гематурия, никтурия.\u003Cbr\u003EНарушения со стороны половых органов и грудной железы:\u003Cbr\u003Eнечасто: менопаузальные симптомы; редко: приапизм, простатит;\u003Cbr\u003Eчастота неизвестна: галакторея.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения:\u003Cbr\u003Eнечасто: астения, боль в груди;\u003Cbr\u003Eредко: утомляемость, боль, жажда."},{"name":"Фармакологическое действие","value":"Синтетический аналог гормона шишковидного тела (эпифиза); оказывает адаптогенное, седативное, снотворное действие. Нормализует циркадные ритмы. Увеличивает концентрацию гамма-аминомасляной кислоты (ГАМК) и серотонина в среднем мозге и гипоталамусе, изменяет активность пиридоксалькиназы, участвующей в синтезе ГАМК, дофамина и серотонина. Регулирует цикл сон-бодрствование, суточные изменения локомоторной активности и температуры тела, положительно влияет на интеллектуально-мнестические функции мозга, на эмоционально-личностную сферу. Способствует организации биологического ритма и нормализации ночного сна. Улучшает качество сна, ускоряет засыпание, регулирует нейроэндокринные функции. Адаптирует организм метеочувствительных людей к изменениям погодных условий."},{"name":"Фармакологическая группа","value":"адаптогенное средство"},{"name":"Форма выпуска","value":"таблетки, покрытые пленочной оболочкой"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"В защищенном от света месте, при температуре не выше 25 °С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"По имеющимся литературным данным, применение мелатонина в суточной дозе до 300 мг не вызывало клинически значимых нежелательных реакций. Наблюдались гиперемия, спазмы в брюшной полости, диарея, головная боль и скотома при применении мелатонина в дозах 3000-6600 мг в течение нескольких недель. При применении очень высоких доз мелатонина (до 1 г) наблюдалась непроизвольная потеря сознания.\u003Cbr\u003EПри передозировке возможно развитие сонливости.\u003Cbr\u003EЛечение - промывание желудка и применение активированного угля, симптоматическая терапия.\u003Cbr\u003EКлиренс активного вещества предполагается в пределах 12 часов после приема внутрь."},{"name":"Применение при беременности и кормлении грудью","value":"Препарат противопоказан к применению при беременности и в период грудного вскармливания."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Препарат Мелатонин-СЗ вызывает сонливость, в связи с этим в период лечения следует воздержаться от вождения автотранспорта и занятий потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"В период применения препарата Мелатонин-СЗ рекомендуется избегать пребывания на ярком свету.\u003Cbr\u003EНеобходимо проинформировать женщин, желающих забеременеть, о наличии у препарата слабого контрацептивного действия.\u003Cbr\u003EОтсутствуют клинические данные о применении мелатонина у больных с аутоиммунными заболеваниями, в связи с чем применение у данной категории пациентов не рекомендуется.\u003Cbr\u003EС осторожностью:\u003Cbr\u003EПрепарат Мелатонин-СЗ нужно применять с осторожностью пациентам с различной степенью почечной недостаточности.\u003Cbr\u003EСледует соблюдать осторожность в отношении пациентов, принимающих флувоксамин, который повышает концентрацию мелатонина за счет ингибирования его метаболизма изоферментами цитохрома Р450 (CYP): CYP1A2 и CYP2C19. Следует избегать такой комбинации.\u003Cbr\u003E Следует соблюдать осторожность в отношении пациентов, принимающих 5- и 8-метоксипсорален, который повышает концентрацию мелатонина вследствие ингибирования его метаболизма.\u003Cbr\u003EСледует соблюдать осторожность в отношении пациентов, принимающих циметидин, поскольку он повышает содержание мелатонина в плазме за счет ингибирования последнего.\u003Cbr\u003EСледует соблюдать осторожность в отношении пациентов, принимающих эстрогены (например, контрацептивы или заместительную гормональную терапию), которые увеличивают концентрацию мелатонина путем ингибирования их метаболизма изоферментами CYP1А1 и CYP1A2."},{"name":"Взаимодействие","value":"Фармакокинетическое взаимодействие\u003Cbr\u003E- Известно, что в концентрациях, значительно превышающих терапевтические, мелатонин индуцирует изофермент CYP3A in vitro. Клиническое значение этого явления до конца не выяснено. В случае развития признаков индукции следует рассмотреть вопрос о снижении дозы одновременно применяемых лекарственных средств.\u003Cbr\u003E- В концентрациях, значительно превышающих терапевтические, мелатонин не индуцирует изоферменты группы CYP1A in vitro. Следовательно, взаимодействие мелатонина с другими лекарственными средствами вследствие влияния мелатонина на изоферменты группы CYP1A, по-видимому, незначимо.\u003Cbr\u003E- Метаболизм мелатонина, главным образом, опосредован изоферментами CYP1A. Следовательно, возможно взаимодействие мелатонина с другими лекарственными средствами вследствие влияния мелатонина на изоферменты группы CYP1 А.\u003Cbr\u003E-Курение способно снизить концентрацию мелатонина за счет индукции изофермента CYP1A2.\u003Cbr\u003E- Ингибиторы изоферментов CYPA2, например, хинолоны, способны повышать экспозицию мелатонина.\u003Cbr\u003E- Индукторы изофермента CYP1A2, такие как карбамазепин и рифампицин, способны снижать плазменную концентрацию мелатонина.\u003Cbr\u003E- В современной литературе имеется множество данных, касающихся влияния агонистов/антагонистов адренергических и опиоидных рецепторов, антидепрессантов, ингибиторов простагландинов, бензодиазепинов, триптофана и алкоголя на секрецию эндогенного мелатонина. Исследования взаимного влияния этих препаратов на динамику или кинетику мелатонина не проводилось.\u003Cbr\u003EФармакодинамическое взаимодействие\u003Cbr\u003E- Во время приема мелатонина не следует употреблять алкоголь, так как он снижает эффективность препарата.\u003Cbr\u003E- Мелатонин потенцирует седативное действие бензодиазепиновых и небензодиазепиновых снотворных средств, таких как залеплон, золпидем и зопиклон. В ходе клинического исследования наблюдались четкие признаки транзиторного фармакодинамического взаимодействия между мелатонином и золпидемом спустя час после их приема. Комбинированное применение может приводить к прогрессирующему расстройству внимания, памяти и координации в сравнении с монотерапией золпидемом.\u003Cbr\u003E- В ходе исследований мелатонин назначался совместно с тиоридазином и имипрамином, препаратами, которые влияют па центральную нервную систему. Ни в одном из случаев не было выявлено клинически значимого фармакокинетического взаимодействия. Тем не менее, одновременное применение с мелатонином приводило к повышению ощущения спокойствия и к затруднениям в выполнении определенных заданий в сравнении с монотерапией имипрамином, а также к усилению чувства \"помутнения в голове\", в сравнении с монотерапией тиоридазином."},{"name":"Регистрационный номер","value":"ЛП-004758"},{"name":"Дата государственной регистрации","value":"13.05.2019"},{"name":"Владелец регистрационного удостоверения","value":"Северная Звезда"},{"name":"Изготовитель","value":"Северная Звезда"},{"name":"Фасовщик","value":"Северная Звезда"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Мелатонин-СЗ"},{"name":"Срок годности","value":"36 мес."}]}],"transitionId":"tr_6"}}}}
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Цена с картой Яндекс Пэй:588 ₽

Скидка: 2%
–2 %
Вместо: 600 ₽
  • 26 мая, курьер Маркета • 99 ₽
POLZAru
Рейтинг 4.9 из 5
37Котзывов
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почечная недостаточность, беременность, период грудного вскармливания, детский возраст до 18 лет."},{"description":"","filters":[{"id":15768292,"name":"Состав"}],"isMainProperty":false,"name":"Состав","value":"1 таблетка содержит:\u003Cbr\u003Eдействующее вещество: мелатонин - 3 мг\u003Cbr\u003Eвспомогательные вещества: целлюлоза микрокристаллическая 102 - 48,5 мг; карбоксиметилкрахмал натрия - 6,5 мг; кальция гидрофосфата дигидрат - 41,0 мг; магния стеарат - 1,0 мг\u003Cbr\u003Eсостав оболочки: гипромеллоза - 1,53 мг; полисорбат-80 (твин-80) - 0,64 мг; тальк - 0,51 мг; титана диоксид Е 171 - 0,32 мг."},{"description":"","filters":[{"id":27144131,"name":"Действующее вещество"}],"isMainProperty":false,"name":"Действующее вещество","value":"Мелатонин"},{"description":"","filters":[{"id":15768000,"name":"Способ применения и дозы"}],"isMainProperty":false,"name":"Способ применения и дозы","value":"Внутрь.\u003Cbr\u003EПри нарушении сна - по 3 мг один раз в сутки за 30-40 минут до сна.\u003Cbr\u003EПри десинхронозе в качестве адаптогена при смене часовых поясов - за 1 день до перелета и в последующие 2-5 дней - по 3 мг за 30-40 минут до сна.\u003Cbr\u003EМаксимальная суточная доза - 6 мг.\u003Cbr\u003EПожилые пациенты\u003Cbr\u003EС возрастом происходит снижение метаболизма мелатонина, что необходимо учитывать при выборе режима дозирования для пожилых пациентов.\u003Cbr\u003EС учетом этого у пациентов пожилого возраста, возможен прием препарата за 60-90 минут до сна.\u003Cbr\u003EПациентам с тяжелой почечной недостаточностью применение препарата не рекомендуется."},{"description":"","filters":[{"id":15767998,"name":"Побочные действия"}],"isMainProperty":false,"name":"Побочные действия","value":"Классификация частоты развития побочных эффектов согласно рекомендациям Всемирной Организации Здравоохранения: очень часто (≥1/10), часто (от ≥1/100 до \u003C1/10), нечасто (от ≥1/1000 до \u003C1/100), редко (от ≥1/10000 до \u003C1/1000), очень редко (\u003C 1/10000), включая отдельные сообщения; частота неизвестна (по имеющимся данным установить частоту возникновения не представляется возможным).\u003Cbr\u003EИнфекционные и паразитарные заболевания:\u003Cbr\u003Eредко: опоясывающий герпес.\u003Cbr\u003EНарушения со стороны крови и лимфатической системы:\u003Cbr\u003Eредко: лейкопения, тромбоцитопения.\u003Cbr\u003EНарушения со стороны иммунной системы:\u003Cbr\u003Eчастота неизвестна: реакции гиперчувствительности.\u003Cbr\u003EНарушения со стороны обмена веществ и питания:\u003Cbr\u003Eредко: гипертриглицеридемия, гипокалиемия, гипонатриемия.\u003Cbr\u003EНарушения психики:\u003Cbr\u003Eнечасто: раздражительность, нервозность, беспокойство, бессонница, необычные сновидения, ночные кошмары, тревога;\u003Cbr\u003Eредко: перемены настроения, агрессия, ажитация, плаксивость, симптомы стресса, дезориентация, раннее утреннее пробуждение, повышение либидо, сниженное настроение, депрессия.\u003Cbr\u003EНарушения со стороны нервной системы:\u003Cbr\u003Eнечасто: мигрень, головная боль, вялость, психомоторная гиперактивность, головокружение, сонливость;\u003Cbr\u003Eредко: обморок, нарушение памяти, нарушение концентрации внимания, делирий, синдром \"беспокойных ног\", плохое качество сна, парестезии.\u003Cbr\u003EНарушения со стороны органа зрения:\u003Cbr\u003Eредко: снижение остроты зрения, нечеткость зрения, повышенное слезотечение.\u003Cbr\u003EНарушения со стороны органа слуха и лабиринтные нарушения:\u003Cbr\u003Eредко: вертиго, позиционное вертиго.\u003Cbr\u003EНарушения со стороны сердечно-сосудистой системы:\u003Cbr\u003Eнечасто: артериальная гипертензия;\u003Cbr\u003Eредко: стенокардия напряжения, ощущение сердцебиения, приливы.\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта:\u003Cbr\u003Eнечасто: абдоминальная боль, абдоминальная боль в верхней части живота, диспепсия, язвенный стоматит, сухость во рту, тошнота;\u003Cbr\u003Eредко: гастроэзофагеальная болезнь, желудочно-кишечное нарушение или расстройство, буллезный стоматит, язвенный глоссит, рвота, усиление перистальтики, вздутие живота, гиперсекреция слюны, неприятный запах изо рта, абдоминальный дискомфорт, дискинезия желудка, гастрит.\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей:\u003Cbr\u003Eнечасто: гипербилирубинемия.\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей:\u003Cbr\u003Eнечасто: дерматит, потливость по ночам, зуд и генерализованный зуд, сыпь, сухость кожи;\u003Cbr\u003Eредко: экзема, эритема, дерматит рук, псориаз, генерализованная сыпь, зудящая сыпь, поражение ногтей;\u003Cbr\u003Eчастота неизвестна: отек Квинке, отек слизистой оболочки полости рта, отек языка.\u003Cbr\u003EНарушения со стороны скелетно-мышечной и соединительной ткани:\u003Cbr\u003Eнечасто: боль в конечностях;\u003Cbr\u003Eредко: артрит, мышечный спазм, боль в шее, ночные судороги.\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей:\u003Cbr\u003Eнечасто: глюкозурия, протеинурия;\u003Cbr\u003Eредко: полиурия, гематурия, никтурия.\u003Cbr\u003EНарушения со стороны половых органов и грудной железы:\u003Cbr\u003Eнечасто: менопаузальные симптомы; редко: приапизм, простатит;\u003Cbr\u003Eчастота неизвестна: галакторея.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения:\u003Cbr\u003Eнечасто: астения, боль в груди;\u003Cbr\u003Eредко: утомляемость, боль, жажда."},{"description":"","filters":[{"id":15768001,"name":"Фармакологическое действие"}],"isMainProperty":false,"name":"Фармакологическое действие","value":"Синтетический аналог гормона шишковидного тела (эпифиза); оказывает адаптогенное, седативное, снотворное действие. Нормализует циркадные ритмы. Увеличивает концентрацию гамма-аминомасляной кислоты (ГАМК) и серотонина в среднем мозге и гипоталамусе, изменяет активность пиридоксалькиназы, участвующей в синтезе ГАМК, дофамина и серотонина. Регулирует цикл сон-бодрствование, суточные изменения локомоторной активности и температуры тела, положительно влияет на интеллектуально-мнестические функции мозга, на эмоционально-личностную сферу. Способствует организации биологического ритма и нормализации ночного сна. Улучшает качество сна, ускоряет засыпание, регулирует нейроэндокринные функции. Адаптирует организм метеочувствительных людей к изменениям погодных условий."},{"description":"","filters":[{"id":34045110,"name":"Фармакологическая группа"}],"isMainProperty":false,"name":"Фармакологическая группа","value":"адаптогенное средство"},{"description":"","filters":[{"id":27141511,"name":"Форма выпуска для карточки"}],"isMainProperty":false,"name":"Форма выпуска","value":"таблетки, покрытые пленочной оболочкой"},{"description":"","filters":[{"id":35947170,"name":"Способ применения/введения"}],"isMainProperty":false,"name":"Способ применения/введения","value":"пероральный"},{"description":"","filters":[{"id":23679511,"name":"Минимальный возраст применения"},{"id":16082123,"name":"С рождения"}],"isMainProperty":false,"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","specs":[{"description":"","filters":[{"id":15767999,"name":"Условия хранения"}],"isMainProperty":false,"name":"Условия хранения","value":"В защищенном от света месте, при температуре не выше 25 °С. Хранить в недоступном для детей месте."},{"description":"","filters":[{"id":15768014,"name":"Передозировка"}],"isMainProperty":false,"name":"Передозировка","value":"По имеющимся литературным данным, применение мелатонина в суточной дозе до 300 мг не вызывало клинически значимых нежелательных реакций. Наблюдались гиперемия, спазмы в брюшной полости, диарея, головная боль и скотома при применении мелатонина в дозах 3000-6600 мг в течение нескольких недель. При применении очень высоких доз мелатонина (до 1 г) наблюдалась непроизвольная потеря сознания.\u003Cbr\u003EПри передозировке возможно развитие сонливости.\u003Cbr\u003EЛечение - промывание желудка и применение активированного угля, симптоматическая терапия.\u003Cbr\u003EКлиренс активного вещества предполагается в пределах 12 часов после приема внутрь."},{"description":"","filters":[{"id":15768015,"name":"Применение при беременности и кормлении грудью"}],"isMainProperty":false,"name":"Применение при беременности и кормлении грудью","value":"Препарат противопоказан к применению при беременности и в период грудного вскармливания."},{"description":"","filters":[{"id":17360993,"name":"Влияние на способность управлять транспортом и механизмами"}],"isMainProperty":false,"name":"Влияние на способность управлять транспортом и механизмами","value":"Препарат Мелатонин-СЗ вызывает сонливость, в связи с этим в период лечения следует воздержаться от вождения автотранспорта и занятий потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций."},{"description":"","filters":[{"id":15771167,"name":"Особые указания"}],"isMainProperty":false,"name":"Особые указания","value":"В период применения препарата Мелатонин-СЗ рекомендуется избегать пребывания на ярком свету.\u003Cbr\u003EНеобходимо проинформировать женщин, желающих забеременеть, о наличии у препарата слабого контрацептивного действия.\u003Cbr\u003EОтсутствуют клинические данные о применении мелатонина у больных с аутоиммунными заболеваниями, в связи с чем применение у данной категории пациентов не рекомендуется.\u003Cbr\u003EС осторожностью:\u003Cbr\u003EПрепарат Мелатонин-СЗ нужно применять с осторожностью пациентам с различной степенью почечной недостаточности.\u003Cbr\u003EСледует соблюдать осторожность в отношении пациентов, принимающих флувоксамин, который повышает концентрацию мелатонина за счет ингибирования его метаболизма изоферментами цитохрома Р450 (CYP): CYP1A2 и CYP2C19. Следует избегать такой комбинации.\u003Cbr\u003E Следует соблюдать осторожность в отношении пациентов, принимающих 5- и 8-метоксипсорален, который повышает концентрацию мелатонина вследствие ингибирования его метаболизма.\u003Cbr\u003EСледует соблюдать осторожность в отношении пациентов, принимающих циметидин, поскольку он повышает содержание мелатонина в плазме за счет ингибирования последнего.\u003Cbr\u003EСледует соблюдать осторожность в отношении пациентов, принимающих эстрогены (например, контрацептивы или заместительную гормональную терапию), которые увеличивают концентрацию мелатонина путем ингибирования их метаболизма изоферментами CYP1А1 и CYP1A2."},{"description":"","filters":[{"id":15768012,"name":"Взаимодействие"}],"isMainProperty":false,"name":"Взаимодействие","value":"Фармакокинетическое взаимодействие\u003Cbr\u003E- Известно, что в концентрациях, значительно превышающих терапевтические, мелатонин индуцирует изофермент CYP3A in vitro. Клиническое значение этого явления до конца не выяснено. В случае развития признаков индукции следует рассмотреть вопрос о снижении дозы одновременно применяемых лекарственных средств.\u003Cbr\u003E- В концентрациях, значительно превышающих терапевтические, мелатонин не индуцирует изоферменты группы CYP1A in vitro. Следовательно, взаимодействие мелатонина с другими лекарственными средствами вследствие влияния мелатонина на изоферменты группы CYP1A, по-видимому, незначимо.\u003Cbr\u003E- Метаболизм мелатонина, главным образом, опосредован изоферментами CYP1A. Следовательно, возможно взаимодействие мелатонина с другими лекарственными средствами вследствие влияния мелатонина на изоферменты группы CYP1 А.\u003Cbr\u003E-Курение способно снизить концентрацию мелатонина за счет индукции изофермента CYP1A2.\u003Cbr\u003E- Ингибиторы изоферментов CYPA2, например, хинолоны, способны повышать экспозицию мелатонина.\u003Cbr\u003E- Индукторы изофермента CYP1A2, такие как карбамазепин и рифампицин, способны снижать плазменную концентрацию мелатонина.\u003Cbr\u003E- В современной литературе имеется множество данных, касающихся влияния агонистов/антагонистов адренергических и опиоидных рецепторов, антидепрессантов, ингибиторов простагландинов, бензодиазепинов, триптофана и алкоголя на секрецию эндогенного мелатонина. Исследования взаимного влияния этих препаратов на динамику или кинетику мелатонина не проводилось.\u003Cbr\u003EФармакодинамическое взаимодействие\u003Cbr\u003E- Во время приема мелатонина не следует употреблять алкоголь, так как он снижает эффективность препарата.\u003Cbr\u003E- Мелатонин потенцирует седативное действие бензодиазепиновых и небензодиазепиновых снотворных средств, таких как залеплон, золпидем и зопиклон. В ходе клинического исследования наблюдались четкие признаки транзиторного фармакодинамического взаимодействия между мелатонином и золпидемом спустя час после их приема. Комбинированное применение может приводить к прогрессирующему расстройству внимания, памяти и координации в сравнении с монотерапией золпидемом.\u003Cbr\u003E- В ходе исследований мелатонин назначался совместно с тиоридазином и имипрамином, препаратами, которые влияют па центральную нервную систему. Ни в одном из случаев не было выявлено клинически значимого фармакокинетического взаимодействия. 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Ещё может подойти

  • Мелатонин Эвалар таб. п/о плен., 3 мг, 40 шт., 1 уп.
    –2 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-hf020ra2fw/toggleWishlist":{"skuId":"868725265","productId":1404748770,"offerId":"CRD8zSgv6pxRAWZuIy5-BA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ7JG0+OXo5LJFEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYI4ofrnQUQkeSengMY1buhBiDt2cEH","sign":"jhRhwgcPwLIb+pWadHjav/DLTMq6LwMyOgC6suTQ7ME="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-hf020ra2fw/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Мелатонин Эвалар таб. п/о плен., 3 мг, 40 шт., 1 уп.

    Рейтинг товара: 4.5 из 5
    на основе 94 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 545 ₽ вместо 557
    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Эвалар таб. п/о плен., 3 мг, 40 шт., 1 уп.","label":"vt7saf9uwi","count":0,"features":[],"imageMeta":{"namespace":"mpic","groupId":4742551,"key":"img_id5421875106128766174.jpeg"}},"quantity":{"step":1,"minimum":1,"maximum":999},"cpaUrl":"/safeclick/data=TxNGOK9vJEN7oLFLeCTKEkrTZoQadGRtjQLqzTxCAYEl31AulbEt2kortXjyKfbNlOHXuzHA2qYTX4CI06xS9iWpu6KHXI6gbTAmtpmWMnkH_Cl5cJEzXJjXSfJ7Fjm_-9orCVf-JdyERCtsBsVBDfltAJtuG7YS-TvbIyQFM4m1dCtgPsTabz2jQJZbFCJX1pqV5vD42gksfisIVv3UNeRtcqpO8Km4A4QfNe4CWb9tDXaoeWqn2Sxw1MkwsVW00QxqKjAkmXiiuv83DMYMUzFxkhmy6uJCy7nEyVHJOXOFF2k-bxZYZgWe_Md88HAujlAedN0B9x3xMCAYddFH7yN5TiT_in16zyIKdI_GWFKSRkknofLvSd20G62kvsqPzKbQHjKxsgDs40RZ0YMoGsgGYwjRT6dgwMVMYXnU8OMLjBE99lMsHo6PLAe36zef1trI7g7ztPZZH3SuqjWt-KXoee-u5Ws3IaJRmyxJAxWL_xCC3-iWswrMxFx9C2y7dxl6ZZJyT29gTt5mf0sIlZcm7X8gi7VcWvn3JkuLo2T1PmnmPXKhrpcvzX3_9wgoxgu_pJ5ecTN25xdd1pEIkHt1O8zl1_iECmhsDbpBOLCvbvnUo1t4sP3IB3o52HWSXlwrr8j9vApmPWowVS5DehtuF5qWBnHhVWddr1iYt4EQjRCbJDMAN59F3xAf3PxnaVY6FSsus_AVTy6MDguODvWAFdZivVcHCk9yHlVAZmoaTeUZP40rCtHNmaZH4140lflWTllgbD2ovFoi__tld5YeUHM59KzuUizH4vQwpu86wMWRlBzZY5XWHAgN0Kn-w4w3WbS_EJ0lvMAVkKCv9CVvBmYp9VJ36wv1LCb8ZJLTdmQz90L8WRxC6xdvDmziV2yKFQoIy6umLY3rE0tdZqsTe-E4sQEcxEsFsMa4KOLIAuruGfAue199pjRJ4WT7A8WgzdrqIPKakJjOUe7RanHRbJ7aFfiDGuZwsUAmfNzklpz3tWxiodd7a-jImlHgWGWBo9OWNgXpLrJGuqDMCMNvVRJXeZzMLhyAOHb5ZgB7gEtUvk9PRA2TXhfalDPL9ooWJm-o7sQ5hujxfnxeidqYsrYJeRpC_jTnDztRixUgFNh9u9f89hsiP4No1mkLIJBdGv3Elp3nIBO--9T-wWATKwZ6F3ff0b0U9zhj9Bz2ptaC7cjAq5Ngn25NN5Z81BZ4UIyb4Eah_Gjy6YSmEOP9-48ibhBcLgB2hg-72dInllcKwp-JYRy9FvmfGzPJyLvR75Zx0NPNoR6bnMiVCSXyHvpX5b8XWBf4rvZ1_h15pkmzljSve-ars9TCQ-2KJvfwFe7u_QOOETySBKHgOMPXmOVw2lJGpIliO6nYkkbOLro6tVOmah-IEpHNV8Qv0YR_4UIaZpzQ0IQnLknW572moiHo7oJIpGQ9D-XlJakpKElcTAuGQujUE-fGnxLBToAJlZdLtdiF2S4Yqj8xbamsM5EiBF0nB8035wOlWxga93yEvTZ_jtUIQZBa2tTb4SBryy4EkNuq1WBShHuD0PO1CmtF-dJpxM2L-zSF96Jp-ciYFgXdxHd-wOK4lRV7K3Kgqao38MjpNznsMSRuXHuW99Z-unFRP_-cefPZ81Gff_JCGINjEdlYf7HUjGtlFjrpoQae856LO4VF2pNyeorKBojUG3B62oxTew2uBKVTZaJQ0w2EUVQfVcNxvgKBx7meF5R5CZGgCj4rTvZ04HLswh-aAnB9sCgAI0Gf4Oq4nhkvzgQthARm8Dz4qwxYhCeSdtGDIo19PStpCvX6XyxZZu-nJw6CObs78l_YqL4zP1x8JUl8KcE9HCPBrykANl4WYX0IgiWrixcn_uCM_dU7-rT6e86HIg6GS0M5mHqoXHR9n13Vjb0296_FYbutu7dtEn0dYySwvGHox7JUHxyTx2kOAzJlhCyM_nUGEAns-OeKezQbS7DOUwuroRbDJ0gnlXtJlZdT4VTsoGdg6mpear3A7MmSW--XEXcgBN7mfL2Ydr8mHhu_64ZHQ0JsE2Oauf6ouFYK4BffrktVvROFoGP9FVyjDWqw4n0Els231n0OBrAxw-DtoDn-vwmoXKt6sCSy7A2TchAMSzoY71xqSvJCZ5rVRTlfVHHVw6jQJ_u8RORGIc31iHv8RgKAtKGIItyW7eVlC4Fli5AzEPtZFnBwwbl7YSGXCiogy0KZ_w5hg6OlzWaTmKTrG_1wIcbYBffIVwzXo9fFOuyvrkPLMaFDzG0EpTB_6V5vd_2CS5G5UlT4WcGGOelsBvSOQ1e4DGiY96kB6WVTHqBM7tdb0SgQxU-wyIHN_t7-oZHCkZxflGBcSACr6emzpvhmE0PlpOeatHXUroWXDut89Q_mK59qM-Mx4lI9g2BkcE3JhZiCg-6mDpjnPXQJWIgMNtXeG9flPLtaafakvO-Eau9Rv35t_qOe0J2c-qrGJp0G4EA1nK8Wa3IHW7YUzcmJ1dfIu0rNfBGc3VDqHYuTMzCKOuWn36PKUnCVrJRkpzfEFszzmgeuwoNUYRUDQDXUwqx3X_sEoXnVshKIj9QXBDTFPNco3qVRz57x4uLBdi_P-Yv3ohX1SAzyJ2Ndnv7RVtFk9Ddb8sue0Rx-XFEQ8X9Od9BlCzwbQ_BpajN5AAmy4gSlkmOGOa4OGsrp8ACqioh6UmLfPJaok2UW3lkr-efgQwsAY3wCI5jhaaeFTSam3flBGyEyVQD59AzWgJ7bFFZ_IT1DEcH2z1UgtSgEqocjGmEKr35dVlNguSxd0iM4CcQzxFjy6iEgzTnxN51p9BZk19weqVRdlzK0sAvyWPA3Ac_uQcIvvwRvrArL4ZvCAMW2Q8T10qfuDRuqAYZerIG7PImYe0wHPO3sz0v9tkYNv91kbUxVwrqxHIw_TECG53uGzXe-5z4P-dz3q5VeY70sdcIAOU5vyIWqp9WCDIimi77kmrgoBuTSGWBqGPEf7oOfRXyOw4u5XlD_OSOWlFhWheqHkjEnzJ-Nj1hY8-y-W80IS5bslmf0uQtLgRZqjQUhxz7xw2CJfE1THEySY7iQPM-gOaUycwab6vkwBHXhZmXKTYmrwc4paVarmjHLW0SbCoy5xUwal_1XmWzeQAli146BjKoJmAMCi06j0LbFpbBqXf5vzLUiZc4ewb5SGp5D-oFH5HyN8AkKf1OpT7dzDKOq9L7lfB4hNYNz-E2bu1JIw4rvxtdJCqDKIuwEZXC2D1hJHLFbQtLLbLqHWrxmpuXomoljUsJ_XvNjb1ybP0DzYgK83rJbPVTk1qDZrNkYCwVt3VYLY0AYxjPQuxOenn-RT31wZmcGhlFbrYYANlZ5HIWwY4P40FUf8C3pGQAD6o68iFLW43wfZogjNWe8ncBePdOAEVoBCRrOKVZTfgdEwpHqW2xkDmlEE0sEQsY-7nH-ASMFMUq1W0vUgvDlQhQXGHOJxC2JLmFufMeX2haUclaAAPsxJlWwbc2iXGJQQZmpa7OeaPKjDqVL2RQkiWewtf-7CGwhUSMO2lAnICotvklc2HKEAC8FH2U,/b64e=1/sign=46323935d8182b84f7ac657f06d5da08/keyno=MARKET_1/*","showUid":"17164874047728152957906001","cartLink":"/my/cart","showNotificationWhenDeleteItem":true,"isLavka":false,"isError":false,"isEats":false,"isCR":false,"isM2bEdoOnlyEnable":false,"isEatsMarketIntegration":true,"isCartButtonNext":false,"isUpsalePopupCRExp":false,"baobabClientDataAdditionToCart":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ7JG0+OXo5LJFEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYI4ofrnQUQkeSengMY1buhBiDt2cEH","sign":"jhRhwgcPwLIb+pWadHjav/DLTMq6LwMyOgC6suTQ7ME="},"target":"cart_addition"},"baobabClientDataDeletionFromCart":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ7JG0+OXo5LJFEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYI4ofrnQUQkeSengMY1buhBiDt2cEH","sign":"jhRhwgcPwLIb+pWadHjav/DLTMq6LwMyOgC6suTQ7ME="},"target":"cart_deletion"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-hf020ra2fw/addToCartButton":{"name":"@light/AddToCartButtonSnippet"}}}
  • Глицин+Мелатонин Эвалар таб. п/языч., 20 шт.
    –2 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-fvaok3g55nl/toggleWishlist":{"skuId":"101762346818","productId":1754588421,"offerId":"AjpPzvBHYRXrODMPRlFnMg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ7JG0+OXo5LJFEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIhcrTxAYQwt6IjPsCGNW7oQYg7dnBBw==","sign":"DQnSxfp/SGhqldkpdHwgr1ETMei4xN/GufpxgrzL0cE="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-fvaok3g55nl/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Глицин+Мелатонин Эвалар таб. п/языч., 20 шт.

    Рейтинг товара: 4.5 из 5
    на основе 51 оценка
    С картой  Пэй
    Цена с картой Яндекс Пэй 774 ₽ вместо 790
    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Эвалар таб. п/языч., 20 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  • Мелаксен таб., 3 мг, 24 шт.
    –1 %
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    Мелаксен таб., 3 мг, 24 шт.

    Рейтинг товара: 4.8 из 5
    на основе 170 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 722 ₽ вместо 729
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  • Соннован таб. п/о плен., 3 мг, 30 шт.
    –2 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-die89n003ar/toggleWishlist":{"skuId":"228073221","productId":1404748622,"offerId":"y2L4qHFpCmN7TzeMeRcGLA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ7JG0+OXo5LJFEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIzobrnQUQhb7gbBjq+oYRIO3ZwQc=","sign":"ADVBUjpaowpSQ/gnU2H2RBmiiZT6tRsvbfzxhzMLfLw="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-die89n003ar/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Соннован таб. п/о плен., 3 мг, 30 шт.

    Рейтинг товара: 4.3 из 5
    на основе 3 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 556 ₽ вместо 568
    {"widgets":{"@light/AddToCartButtonSnippet":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-die89n003ar/addToCartButton":{"offerId":"y2L4qHFpCmN7TzeMeRcGLA","skuId":"228073221","pendingCartItem":{"productId":1404748622,"offerId":"y2L4qHFpCmN7TzeMeRcGLA","showPlaceId":"OTNDnItfwRMjN9MRHuEMMnyDGTitMwzVRKN_OhA-9qlzp2r8Cbvszk_pecBMn1Ev4HpQab_sSjQ0NaUyhl_jTHQdWlA3C0pLJQfpZUiwSoSL5qMAFDw8aiAojUHBNuaz3da-niOVgzNk-hklrKOHB3YN2di5zrNI6O__oxdiNyHL5M_zfKC0wZgh8lWK40ogxgXdrE3kxCwQM4hKwdWwdbnGdUxePIt0q9DAQr6DEx8,","feeShow":"OTNDnItfwRMjN9MRHuEMMnyDGTitMwzVRKN_OhA-9qlzp2r8Cbvszk_pecBMn1Ev4HpQab_sSjQ0NaUyhl_jTHQdWlA3C0pLJQfpZUiwSoSL5qMAFDw8aiAojUHBNuaz3da-niOVgzNk-hklrKOHB3YN2di5zrNI6O__oxdiNyHL5M_zfKC0wZgh8lWK40ogxgXdrE3kxCwQM4hKwdWwdbnGdUxePIt0q9DAQr6DEx8,","skuId":"228073221","shopId":431782,"price":{"applicablePriceDiscounts":[{"priceWithDiscount":"556","type":"ya-card","totalPercentWithDiscount":2}],"value":"568","currency":"RUR"},"hid":"15756525","name":"Соннован таб. п/о плен., 3 мг, 30 шт.","label":"d7r13helxvp","count":0,"features":[],"imageMeta":{"namespace":"mpic","groupId":4346078,"key":"img_id6252837170548514842.jpeg"}},"quantity":{"step":1,"minimum":1,"maximum":999},"cpaUrl":"/safeclick/data=TxNGOK9vJEN7oLFLeCTKEixJYuEMI0EzvZFs82AjjgjhTwweZ7mRXd_AQ0K184sfZmy5nQz7U8xIc-qdVOMFoxnoSww2ObzLEs1KJpltGipDSanCui6QCo8GXRHxAQaqQQZbzp5kb0bdQDXqQiIIDEwL4INEBUjrbUNtjxqZ96WFVmZtSFtMyb3yJJ0vvI_f_VoLwr8_fQAEQQQYfoC_N9zWZn9uYbm1nYrocCgs5ba5zwi1SUbXFAOUBzEUWfwtVXQSMTNdEnnHR8whFkaSXgr-z1gx6xy8JFxLNsk0eWemtYpO8Y1nOSQILhsLnQBWMfvG2ELj-vCxovx4tdD7x5wNGKxqUwtjod-MdUuK2TbzYTnrTQFA9shhvVwr2QMfTS2zELigsqwkSsWkPZ_tDwQFeDn8dwsuM1KuvodcuixStPjrIjdakuPHqqkduqA2oSII0azTPaTQAI4oX_1acfiiqVVB3d_K4f6D4jPGfobTa8ZhgBg3YW8fKqK0MGza908FUI8-S4PbLVhNdWaXsQhnCntUDPwjITdO9APz8qsiOLxC_L4_ycDvow0y90xZNZBuSiS5FRudt6Arcou6fn01JH7taNCjjj4df3LGFWbpVi1bRXfxC1g9i2zUyweD7G9MkGaJWrHbTJLFMNwby6RtfOn4PGKn5KqECBLGXKmu4eiNbsG5wowyyOT4vTdf8-vw2ojLVEyc_mxJCKcGkwz3bly3sbRGX9hdLK9YP1S2JnH0gmwT4G8OIqJMZTaCiJrYoN1-312UudxqVrjR1m0Te91uKQGsov96VurrwroiXnbiFEfHcATtDY1qeIaU9kSMFSHnFNchBk4ZPTx_Gd2cYzwgGu1rRTPg4SgUPvnQA75Hu1N_JXm0wIy18u8plnW_7qsp0RlnoK-2fB2T0VGHO54S1ycaJFz7Nayfng3kvfJahw4qIVRTF_SQ6W_0qc12aJICcIEzu3VpWQ1CBALLc3yhaD_ku_8_V36ibqFKMYDTwVHAUhfwoGbbZ5-givU9ueMfLK2m8KqZVjQN8QJULiU9CEvYzt1GjpkNr9Tpxp6WrTYr_e60VPaQxmTP9i1U6YX_CylooqMI6A2w12xORHAYLjKkABEqfJXWTMaxPpG8jY6rUk4UsCe-rhRlNmt77OaD2IOpdoOer5QheeR_Ij2UNsBg2dY_M-Kzi8FYAytSC4kGgfR9noVbHUv50gW3DCu64jYj7SVJRzy_blCiQKd1XO14_6JTylLZ7Ipi1NRVPeJg8fRK9hEQKHkJTyE5lFqBCAOiO_LrOlC8CNOa6RI1WsKkx1jLbhKYZ69G2Ne7YtqC621-p11ZOwcAjdgYuWf418d4oB2HDfXEH3-WaRh_3_W3_0w5L-T2Zj2IYVXcaOjgaHepUweGQBDqoQUEajW8Jgpfr8Ybcj5ljKRBV8UjdkU0ih9W1C_pIKw1iNzBuh7m9be8qzJWExpGx9KDGIJwqyh8Yz2geIKr5J8Kc0ioFcNyXUqRvjs3osaTfvV0uY1R0mUjwy9hghJcBYjDsbD62r_kHvW5gi1QFywc_w0GAF8y-Lnhn5S9yvBa6EsFrfMv5SvAxRfkeeT2jdt1aNEyd06FfOVdnD9nRbbdgR8zc-5hECkK0KAnZzWpa5v0ZxZhwmoBJ3l95cJfDxtJxDPt-SI3gSkSs1oghdTzdVQlog16wnm8uHgULYbDbHXz6XTAPOtptkac3pbNboSxB1g2bQ47ReOb8XvY9NHSCebNYbBjEguGtxDF8mSvqdlQ8G7629WwrltF3tLS3vL-G7BRuqkhAehHDomGeasC2abJs3-hv-CoBzz7WpetceUN-epXjMByiiL6yuh0zjU-IZDxwx1Jn2bmvkF8gYOGRL9diuuJj2J1bjE8gSzzB4-u8dLlDBoKYkQI6d1Fan7a1StXK1GFpUOLHE2Oxn0gMZOFEs2UHqpKs-OqFjk9MQGjumfJ3_Ij9OtnqhwxZGvGKC824IJ3f7v5wa8CgAoevWN8JjDAMwhS01D0JjD6wuLZjyPZZ4LLz-Mvx8oVp2g16sIa9qZnXHBiD2IsD8xzKiRD23f5_q96YcFr1JcMrcOZlDirT9B3MM9AdhqBIr16AH0-_PEhMl6ZYeCAkYdfRq_WIfW6g7-yIcsCQ9pxLJGIvLf_ewwgPaLe2466nmPfE5OV2QcllwVV9bvIZ35GOijvmKOIWw48Z93-cq6IiyWw-OP9ih6nGAkN2P_Pfn8DfF8XT5mUTyJPAJqeBiBIqVjFtY5uNOuyd_CvbH6Dh3IShktwfpyoIye7BKmQWHgZYFrLqVJZL1zFzZjJoczcrfoInKP7LSOv-t284qYOZixcv3N_1dVsvjnbqbhyrRuWddiqTCgbomiQCbJVuJPqr79gA4E-mU1ZJ46_02EkbATOfWqzBI1_NTi_47uHSsSRuwBTmFvOeeNpcsKmMK4EJrXmrM-_kPYpOqhSQkFtHyPhUTWXUxTJHIS-iFKmYcC-1LOz-CYIu8T5vIDetSqvq2VOrJv6XRObCd1XCI5r_JSTQXiRA9wr-NxsGMHgkpP0PVJU2H8o5Ycrl4pivpf6sxKOfzHIo7Gl0cNTZdtxNKsNpTVoPIwnzHOpWoz65xP32fbtLv1XipIF1YwOkRmEUNL2w495iDk8Qhg8gsXjZG5gQBf1vwHUtPpfrs39pVf2IPLGNoWx1NuwDL_kKXJ0S0q63HFRUQJ3hV8G7CsuVv9GVlg7ejYILjpHEmflagm8xrgEx_bYU07WdjxJsfodViizCaduULQamdlSXwvG4bJojd8Skcl3n_QE3Xz1Qqn1VAE_93hdCmJgETDmRlW8ZZ794kRyk0FGuI0rTOA3TLMQ0ssyVrD1o9gDRhEushXHzSpxbBnWvGidTbaxUsfGlg3Amcv-p3gCTssrtqVJ9lFid0j79SfRcAlF2yG0waeEMtzee5wljfpGZuj3W4sJECmNf_xG8Li50cPGbN3FWdqal-cS0h-LQp4FdMy3AEwNBD6thonOJz14wVUuEc3VAvQplECuWbjGojvfivq2cp1zrNxzvkBDmsivw8VizmCHPC1KYs5lDF8osYpX5m1SqHirs5XB5Y_eA2tIbY0wx0DXYWnQZxjM4SQ1IUXxSzl1VKFiZs_9C4UjoFdkeUHUm8v4QGXl43sIY4H0PvmB1hYwC9irnZIQpWJ-37RUUOEfzLx88i067XcEm39uLLAQwNfzYDyAE4PdXVYh5e2Cze3v2JUvGXG0KxFgNwy7xgiErCmKlWTloejXDC_42NnMaesBq8LZjNBNw2C3N1g-N3MT_Nylq1or6fbAGS4-wwGN6iJluimZdhLofyfcV0FDrBPUrLT-l7eFbjfeK4RK-neWLh6Dfv0VEiRs6y4E6CeheDXT9iiUtpv_BHj5zdsQy9X90PXoj7eu1YwM8Hw,/b64e=1/sign=9f6f5dd2159ceb4e7d36520985b52afa/keyno=MARKET_1/*","showUid":"17164874047627834866306004","cartLink":"/my/cart","showNotificationWhenDeleteItem":true,"isLavka":false,"isError":false,"isEats":false,"isCR":false,"isM2bEdoOnlyEnable":false,"isEatsMarketIntegration":true,"isCartButtonNext":false,"isUpsalePopupCRExp":false,"baobabClientDataAdditionToCart":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ7JG0+OXo5LJFEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIzobrnQUQhb7gbBjq+oYRIO3ZwQc=","sign":"ADVBUjpaowpSQ/gnU2H2RBmiiZT6tRsvbfzxhzMLfLw="},"target":"cart_addition"},"baobabClientDataDeletionFromCart":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ7JG0+OXo5LJFEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIzobrnQUQhb7gbBjq+oYRIO3ZwQc=","sign":"ADVBUjpaowpSQ/gnU2H2RBmiiZT6tRsvbfzxhzMLfLw="},"target":"cart_deletion"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-die89n003ar/addToCartButton":{"name":"@light/AddToCartButtonSnippet"}}}
  • Мелатонин таб. п/о плен., 3 мг, 30 шт., 1 уп.
    –2 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-1sfuem23dkd/toggleWishlist":{"skuId":"101606729738","productId":1664457252,"offerId":"0zz6i0UDxq0LvqDJKrk_pw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ7JG0+OXo5LJFEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIpLTWmQYQitDuwfoCGNfxzwYg7dnBBw==","sign":"zS/Ne6y6W/D7N8SGYeOueBKTZzko7CtnaHOXGffVXgY="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-1sfuem23dkd/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Мелатонин таб. п/о плен., 3 мг, 30 шт., 1 уп.

    Рейтинг товара: 4.8 из 5
    на основе 8 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 670 ₽ вместо 684
    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таб. п/о плен., 3 мг, 30 шт., 1 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  • Велсон таб. п/о плен., 3 мг, 30 шт.
    –21 %
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    Велсон таб. п/о плен., 3 мг, 30 шт.

    Рейтинг товара: 4.3 из 5
    на основе 16 оценок
    Цена 622 ₽ вместо 788
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  • Гармония сна капс., 0.36 г
    –50 %
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    Гармония сна капс., 0.36 г

    Рейтинг товара: 4.5 из 5
    на основе 54 оценки
    Цена 338 ₽ вместо 676
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  • Меларена таб. п/о плен., 3 мг, 30 шт.
    –2 %
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    Меларена таб. п/о плен., 3 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 3 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 591 ₽ вместо 603
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  • Сонные+ таб., 30 шт., 1 уп.
    –31 %
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    Сонные+ таб., 30 шт., 1 уп.

    Рейтинг товара: 4.1 из 5
    на основе 145 оценок
    Цена 275 ₽ вместо 399
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  • Формула сна экспресс таб. д/рассас., 40 шт.
    –10 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-kq34k6hc2n/toggleWishlist":{"skuId":"641533148","productId":1778173019,"offerId":"MAQs_2Iiviru5Qaj7SVQ_Q","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ7JG0+OXo5LJFEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYI24jzzwYQ3In0sQIY1buhBiDt2cEH","sign":"P/ijt3EnEqnI7CMmDbJ1wanKCurnttZflKvtVbEsMyg="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-kq34k6hc2n/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Формула сна экспресс таб. д/рассас., 40 шт.

    Рейтинг товара: 4.3 из 5
    на основе 75 оценок
    Цена 396 ₽ вместо 440
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  • Донормил таб. п/о плен., 15 мг, 30 шт.
    –15 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-mtt59e5sisk/toggleWishlist":{"skuId":"101594757795","productId":228046100,"offerId":"rXU55gkFAKS4S3BvuBHNyQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ7JG0+OXo5LJFEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYIlOrebBCj9ZO8+gIYneHQByDt2cEH","sign":"9KDdHx9NDJQTeMAg8elnlJ9ibyfcEeFOQPR0Iuz6doM="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-mtt59e5sisk/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Донормил таб. п/о плен., 15 мг, 30 шт.

    Рейтинг товара: 4.8 из 5
    на основе 32 оценки
    Цена 424 ₽ вместо 496
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  • Фенибут таб., 250 мг, 20 шт.
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    Фенибут таб., 250 мг, 20 шт.

    Рейтинг товара: 4.8 из 5
    на основе 502 оценки
    Цена 118 ₽
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Инструкция

Показания к применению

При расстройстве сна, в т.ч. обусловленных нарушением ритма "сон- бодрствование", таких как десинхроноз (резкая смена часовых поясов).

Противопоказания

Гиперчувствительность к компонентам препарата, аутоиммунные заболевания, печеночная недостаточность, тяжелая почечная недостаточность, беременность, период грудного вскармливания, детский возраст до 18 лет.

Способ применения и дозы

Внутрь.
При нарушении сна - по 3 мг один раз в сутки за 30-40 минут до сна.
При десинхронозе в качестве адаптогена при смене часовых поясов - за 1 день до перелета и в последующие 2-5 дней - по 3 мг за 30-40 минут до сна.
Максимальная суточная доза - 6 мг.
Пожилые пациенты
С возрастом происходит снижение метаболизма мелатонина, что необходимо учитывать при выборе режима дозирования для пожилых пациентов.
С учетом этого у пациентов пожилого возраста, возможен прием препарата за 60-90 минут до сна.
Пациентам с тяжелой почечной недостаточностью применение препарата не рекомендуется.
Полная инструкция
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Мелатонин-СЗ таб. п/о плен.
Мелатонин-СЗ таб. п/о плен., 3 мг, 60 шт., 1 уп.
4.8
(71)
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15 вопросов
Инструкция

Цена с картой Яндекс Пэй:588 ₽

Скидка: 2%
–2 %
Вместо: 600 ₽
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4.8
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У продавца:71 оценка·24 отзыва
У всех продавцов:470 оценок·181 отзыв
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user avatar
6 месяцев назад • Олег В. • Куплен на Маркете
Достоинства: Адекватно действующее средство. Не вызывает заметных побочных эффектов. В два - три раза дешевле аналогичных препаратов других производителей в пересчете на одну таблетку.
Недостатки: Пришлось долго ждать доставки
user avatar
2 месяца назад • татьяна корсунова • Куплен на Маркете
Достоинства: Качественный препарат
Недостатки: Нет
Комментарий: Рекомендую всем у кого есть проблемы со сном, за 30 мин рассасываю под языком, так быстрее наступает эффект)
user avatar
Месяц назад • Наталья Печенкина • Куплен на Маркете
Комментарий: Пропила 14 дней по совету из комментариев, сон восстановился.
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  • Капсулы NOW Melatonin, 60 г, 3 мг, 60 шт.
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    Капсулы NOW Melatonin, 60 г, 3 мг, 60 шт.

    Цена 560 ₽ вместо 566
  • Эвалар Чай Эвалар БИО при повышенном содержании мочевой кислоты, 20 фильтр-пакетов
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    Эвалар Чай Эвалар БИО при повышенном содержании мочевой кислоты, 20 фильтр-пакетов

    Цена 194 ₽ вместо 224
  • Мелаксен таб., 3 мг, 24 шт.
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    Мелаксен таб., 3 мг, 24 шт.

    Цена 722 ₽ вместо 729
  • Глицин+Мелатонин Эвалар таб. п/языч., 20 шт.
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    Глицин+Мелатонин Эвалар таб. п/языч., 20 шт.

    Цена 774 ₽ вместо 790
  • Vitamin D3, 10000 МЕ, 120 шт.
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    Vitamin D3, 10000 МЕ, 120 шт.

    Цена 1 148 ₽ вместо 2 455
  • Соннован таб. п/о плен., 3 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1404748622_6/content/content/gallery":{"title":"Соннован таб. п/о плен., 3 мг, 30 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/4346078/img_id6252837170548514842.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4346078/img_id6252837170548514842.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4346078/img_id6252837170548514842.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4346078/img_id6252837170548514842.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4346078/img_id6252837170548514842.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4346078/img_id6252837170548514842.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/7888310/img_id8109801689953884094.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/7888310/img_id8109801689953884094.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/7888310/img_id8109801689953884094.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/7888310/img_id8109801689953884094.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/7888310/img_id8109801689953884094.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/7888310/img_id8109801689953884094.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4367383/img_id4375867665913428253.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4367383/img_id4375867665913428253.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4367383/img_id4375867665913428253.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4367383/img_id4375867665913428253.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4367383/img_id4375867665913428253.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4367383/img_id4375867665913428253.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4466428/img_id2090121862389354021.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4466428/img_id2090121862389354021.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4466428/img_id2090121862389354021.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4466428/img_id2090121862389354021.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4466428/img_id2090121862389354021.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4466428/img_id2090121862389354021.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ7JG0+OXo5LJFEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIVCM6G650FEIW+4GwY6vqGESDt2cEH","sign":"FQlnJU9N1r1+g2NEAkOzoTzniFd5MzlZgaI8+8qogc0="},"target":"model_card"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1404748622_6/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1404748622_6/content/content/toggleWishlist":{"skuId":"228073221","productId":1404748622,"offerId":"y2L4qHFpCmN7TzeMeRcGLA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ7JG0+OXo5LJFEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIVCM6G650FEIW+4GwY6vqGESDt2cEH","sign":"FQlnJU9N1r1+g2NEAkOzoTzniFd5MzlZgaI8+8qogc0="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1404748622_6/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Соннован таб. п/о плен., 3 мг, 30 шт.

    Цена 556 ₽ вместо 568
  • Мелатонин таб. п/о плен., 3 мг, 30 шт., 1 уп.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1664457252_7/content/content/toggleWishlist":{"skuId":"101606729738","productId":1664457252,"offerId":"4cPOfb3jL-5oO4dVRPVUGQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ7JG0+OXo5LJFEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIXCKS01pkGEIrQ7sH6AhjX8c8GIO3ZwQc=","sign":"AAOZ/RQIhr/s9FA/Lj1ri+PT72GgatmLwdpNf9UUSvI="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1664457252_7/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Мелатонин таб. п/о плен., 3 мг, 30 шт., 1 уп.

    Цена 680 ₽ вместо 687
  • Реклама
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  • Велсон таб. п/о плен., 3 мг, 30 шт.
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    Велсон таб. п/о плен., 3 мг, 30 шт.

    Цена 622 ₽ вместо 788
  • ЛимфоТранзит концентрат напитка фл., 100 мл
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    ЛимфоТранзит концентрат напитка фл., 100 мл

    Цена 332 ₽ вместо 390
  • Гармония сна капс., 0.36 г
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    Гармония сна капс., 0.36 г

    Цена 338 ₽ вместо 676
  • Меларена таб. п/о плен., 3 мг, 30 шт.
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    Меларена таб. п/о плен., 3 мг, 30 шт.

    Цена 591 ₽ вместо 603
  • NOW Foods, Magnesium Citrate, цитрат магния, 120 вегетарианских капсул
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    NOW Foods, Magnesium Citrate, цитрат магния, 120 вегетарианских капсул

    Цена 1 673 ₽ вместо 3 200
  • Хронотрон имплантат инъекц. гель для в/суст. введ., 20 мг/мл, 2 мл, 1 шт.
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    Хронотрон имплантат инъекц. гель для в/суст. введ., 20 мг/мл, 2 мл, 1 шт.

    Цена 10 000 ₽
  • Капсулы NOW Biotin, 100 г, 150 мл, 5000 мкг, 60 шт.
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    Капсулы NOW Biotin, 100 г, 150 мл, 5000 мкг, 60 шт.

    Цена 798 ₽ вместо 1 290
  • Сонные+ таб., 30 шт., 1 уп.
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    Сонные+ таб., 30 шт., 1 уп.

    Цена 275 ₽ вместо 399
  • Формула сна экспресс таб. д/рассас., 40 шт.
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    Формула сна экспресс таб. д/рассас., 40 шт.

    Цена 396 ₽ вместо 440
  • Силденафил-СЗ таб. п/о плен., 25 мг, 20 шт.
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    Силденафил-СЗ таб. п/о плен., 25 мг, 20 шт.

    Цена 212 ₽ вместо 262
  • Ревмафлекс капс., 60 шт.
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    Ревмафлекс капс., 60 шт.

    Цена 792 ₽ вместо 950
  • Виферон супп. рект., 500000 МЕ, 10 шт.
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    Виферон супп. рект., 500000 МЕ, 10 шт.

    Цена 483 ₽ вместо 547
  • Реклама
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    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  • Табекс таб. п/о плен., 1.5 мг, 100 шт.
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    Табекс таб. п/о плен., 1.5 мг, 100 шт.

    Цена 1 565 ₽ вместо 1 913
  • Донормил таб. п/о плен., 15 мг, 30 шт.
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    Донормил таб. п/о плен., 15 мг, 30 шт.

    Цена 424 ₽ вместо 496
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