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Описание

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Метрогил А гель д/нар. прим., 0.1%, 20 г

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4.3
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Коротко о товаре

Артикул Маркета
3288321440
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
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Детский возраст до 18 лет (эффективность и безопасность препарата для данной возрастной категории не установлена). Беременность, период грудного вскармливания."},{"name":"Состав","value":"На 1 г препарата: Действующие вещества: Адапален - 1,0 мг Метронидазол - 10,0 мг Вспомогательные вещества: пропиленгликоль — 70,0 мг, полоксамер 124 — 30,0 мг, карбомер (гомополимер тип С) — 7,0 мг, натрия гидроксида раствор 1 М — до РН от 5,0 до 6,5, натрия эдетат — 0,5 мг, вода очищенная — до 1 г."},{"name":"Действующее вещество","value":"Адапален+Метронидазол","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-kozhi","categoryId":"15756517","navnodeId":"25025070","glfilters":["27144131:36089736"]}}},{"name":"Способ применения и дозы","value":"Наружно. Взрослым. Гель следует наносить тонким слоем на пораженные угревой сыпью участки кожи один раз в сутки перед сном на чистую сухую кожу, избегая попадания геля в глаза, на губы, слизистые оболочки и уголки носа. Заметное клиническое улучшение развивается после 4-8 недель лечения, стойкое улучшение после 3-х месячного курса лечения. Поскольку при лечении угревой сыпи принято чередование методов терапии, то через З месяца терапии препаратом рекомендуется проконсультироваться с врачом о дальнейшей терапии. Если после лечения улучшение не наступает или симптомы усугубляются, или появляются новые симптомы, необходимо проконсультироваться с врачом. Применяйте препарат только согласно тем показаниям, тому способу применения и в тех дозах, которые указаны в инструкции по применению."},{"name":"Побочные действия","value":"Частота развития побочных эффектов классифицирована согласно рекомендациям Всемирной организации здравоохранения: очень часто (\u003E 1/10), часто (\u003E 1/100, \u003C 1/10), нечасто (\u003E 1/1000, \u003C 1/100), редко (\u003E 1/10 000, \u003C 1/1000), очень редко (\u003C1/10 000), частота неизвестна: частота не может быть оценена на основании имеющихся данных.\u003Cbr /\u003EНарушения со стороны кожи и подкожных тканей: часто - сухость кожи, раздражение кожи, эритема, зуд, ощущение жжения кожи; нечасто - контактный дерматит, ощущение дискомфорта, солнечный ожог, шелушение кожи, угревая сыпь; частота неизвестна — аллергический дерматит (аллергический контактный дерматит), болезненность кожи, припухлость кожи, раздражение век, эритема век, зуд век, припухлость век, припухлость лица.\u003Cbr /\u003EНарушения со стороны нервной системы: нечасто - гипестезия, парастезия, дисгевзия\u003Cbr /\u003E(«металлический» привкус во рту).\u003Cbr /\u003EНарушения со стороны желуДочно-кишечного тракта: нечасто - тошнота.\u003Cbr /\u003EЕсли у Вас отмечаются побочные эффекты, указанные в инструкции, и они усугубляются, или Вы заметили любые Другие побочные эффекты, не указанные в инструкции, сообщите об этом врачу.\u003Cbr /\u003E"},{"name":"Фармакологическое действие","value":"Адапален — метаболит ретиноида, который действует на патологический механизм развития Аспе vulgaris, является сильным модулятором клеточной дифференцировки и кератинизации и обладает комедонолитической и противовоспалительной активностью. Механизм действия адапалена основан на взаимодействии со специфическими урецепторами эпидермальных клеток кожи. В результате действия адапалена происходит\u003Cbr /\u003Eснижение «сцепленности» эпителиальных клеток в устье сально-волосяного фолликула и уменьшение образования микрокомедонов. Адапален оказывает противовоспалительное действие in vivo и in vitro, воздействуя на факторы воспаления путем ингибирования миграции лейкоцитов в очаге воспаления, угнетает хемотактический и хемокинетический ответы полиморфноядерных лейкоцитов человека и подавляет метаболизм арахидоновой кислоты до медиаторов воспаления, АР-1 факторы и экспрессию ТоП-подобных рецепторов \u003Cbr /\u003EМетронидазол — противопротозойный и противомикробный препарат, производное 5нитроимидазола. Механизм действия заключается в биохимическом восстановлении 5нитрогруппы метронидазола внутриклеточными транспортными протеинами анаэробных микроорганизмов и простейших. Восстановленная 5-нитрогруппа метронидазола взаимодействует с ДНК клетки микроорганизмов, ингибируя синтез их нуклеиновых кислот, что ведет к гибели бактерий.\u003Cbr /\u003EАктивен в отношении Trichomonas vaginalis, Entamaeba histolytica, а также грамотрицательных анаэробов Bacteroides spp. (в т.ч. Bacteroides fragilis, Bacteroides distasonis, Bacteroides ovatus, Bacteroides thetaiotaomicron, Bacteroides vulgatus), Fusobacterium spp. и некоторых грамположительных анаэробов (чувствительные штаммы Eubacterium ,spp., Clostridium spp., Peptococcus niger, Peptostreptococcus spp.). Минимальная подавляющая концентрация (МПК) для этих штаммов составляет 0,1256,25 мкг/мл.\u003Cbr /\u003EК метронидазолу нечувствительны аэробные микроорганизмы и факультативные анаэробы, но в присутствии смешанной флоры (аэробы и анаэробы) метронидазол действует синергично с антибиотиками, эффективными против обычных аэробов.\u003Cbr /\u003E"},{"name":"Фармакологическая группа","value":"средство лечения угревой сыпи"},{"name":"Форма выпуска","value":"гель"},{"name":"Способ применения/введения","value":"наружный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-kozhi","categoryId":"15756517","navnodeId":"25025070","glfilters":["35947170:36763741"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"При температуре не выше 30 ос, в оригинальной упаковке (туба в пачке). Не замораживать! Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Данные по передозировке препарата отсутствуют. При применении препарата в соответствии с инструкцией по применению передозировка маловероятна. При случайном проглатывании даже незначительного количества препарата, следует промыть желудок, при необходимости проводят симптоматическую терапию."},{"name":"Применение при беременности и кормлении грудью","value":"Противопоказано применение препарата при беременности и в период грудного вскармливания."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Препарат Метрогил А не оказывает влияния на способность управлять транспортными средствами и работать с механизмами."},{"name":"Особые указания","value":"С осторожностью При нарушениях со стороны крови, в том числе в анамнезе. \u003Cbr /\u003EНеобходимо тщательно вымыть руки до и после нанесения геля.\u003Cbr /\u003EВ случае возникновения реакций гиперчувствительности или выраженного раздражения применение препарата следует прекратить. В некоторых случаях, в зависимости от степени раздражения кожи, число нанесений может быть сокращено, лечение приостановлено до исчезновения признаков раздражения, либо прекращено. Следует избегать попадания геля в глаза, рот, уголки носа и на слизистые оболочки.\u003Cbr /\u003EВ случае попадания геля в глаза их следует незамедлительно промыть теплой водой. Препарат нельзя наносить на поврежденную в результате травмы (порезы или ссадины), солнечного ожога или экзематозную кожу. Кроме того, его не следует применять у пациентов с тяжелой формой угревой сыпи на обширных участках кожи.\u003Cbr /\u003EМетронидазол является производным нитроимидазола и его следует применять с осторожностью у пациентов с имеющимися в настоящее время либо отмечавшимися в анамнезе нарушениями со стороны крови.\u003Cbr /\u003EПри применении препарата Метрогил@ А следует избегать воздействия искусственного ультрафиолетового облучения (солярии, лампы солнечного света) и воздействия солнечного света (включая солнечные ванны). Под влиянием УФ-лучей метронидазол превращается в неактивный метаболит, в связи с чем возможно значимое снижение эффективности препарата. Если избежать воздействия не представляется возможным, рекомендуется применение солнцезащитных средств и одежды для защиты обработанных препаратом участков кожи.\u003Cbr /\u003EСледует избегать излишнего и длительного применения препарата.\u003Cbr /\u003EПрепарат содержит пропиленгликоль, который может вызывать раздражение кожи.\u003Cbr /\u003E"},{"name":"Взаимодействие","value":"Адапален\u003Cbr /\u003EНе установлено взаимодействий с другими лекарственными средствами, которые могут применяться наружно и одновременно с данным препаратом; тем не менее, одновременно с адапаленом не следует применять другие ретиноиды или препараты со сходным механизмом действия.\u003Cbr /\u003EВсасывание адапалена через кожу является низким, поэтому его взаимодействие с системными лекарственными препаратами маловероятно.\u003Cbr /\u003EОдновременное применение средств для пилинга, абразивных очищающих средств, а также средств с подсушивающим, вяжущим или раздражающим действием\u003Cbr /\u003E(ароматических или спиртсодержащих средств) не рекомендуется.\u003Cbr /\u003EМетронидазол\u003Cbr /\u003EПри применении геля не было зарегистрировано случаев взаимодействия с другими лекарственными средствами.\u003Cbr /\u003EВсасывание метронидазола через кожу является низким, поэтому его взаимодействие с системными лекарственными препаратами маловероятно.\u003Cbr /\u003EТем не менее следует учитывать, что у небольшого количества пациентов отмечались дисульфирамоподобные реакции при одновременном приеме метронидазола внутрь и этанола.\u003Cbr /\u003EПредупреждение соблюдать осторожность при одновременном применении метронидазола с варфарином или другими непрямыми антикоагулянтами из-за возможного удлинения протромбинового времени относится только к метронидазолу для приема внутрь.\u003Cbr /\u003EЕсли Вы применяете вышеперечисленные средства или другие лекарственные препараты (в том числе безрецептурные), перед применением препарата проконсультируйтесь с врачом.\u003Cbr /\u003E"},{"name":"Регистрационный номер","value":"ЛП-006281"},{"name":"Дата государственной регистрации","value":"22.06.2020"},{"name":"Владелец регистрационного удостоверения","value":"Unique Pharmaceuticals","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-kozhi","categoryId":"15756517","navnodeId":"25025070","glfilters":["34324371:35649313","7893318:16002688"]}}},{"name":"Изготовитель","value":"Unique Pharmaceuticals"},{"name":"Страна бренда","value":"Индия"},{"name":"Страна-производитель","value":"Индия"},{"name":"Название препарата","value":"Метрогил","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-kozhi","categoryId":"15756517","navnodeId":"25025070","glfilters":["17796364:18038431"]}}},{"name":"Срок годности","value":"36 мес."}]}},"fullSpecsGrouped":{"2789259688216980241":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Органы и системы","value":"кожа"},{"name":"Назначение","value":"угревая болезнь"},{"name":"Показания к применению","value":"Угревая сыпь легкой и средней степени тяжести, в том числе при наличии комедонов, папул и пустул, с локализацией на коже лица, груди или спины."},{"name":"Противопоказания","value":"Повышенная чувствительность к адапалену, метронидазолу, производным нитроимидазола, имидазолам или любому из вспомогательных веществ. Детский возраст до 18 лет (эффективность и безопасность препарата для данной возрастной категории не установлена). Беременность, период грудного вскармливания."},{"name":"Состав","value":"На 1 г препарата: Действующие вещества: Адапален - 1,0 мг Метронидазол - 10,0 мг Вспомогательные вещества: пропиленгликоль — 70,0 мг, полоксамер 124 — 30,0 мг, карбомер (гомополимер тип С) — 7,0 мг, натрия гидроксида раствор 1 М — до РН от 5,0 до 6,5, натрия эдетат — 0,5 мг, вода очищенная — до 1 г."},{"name":"Действующее вещество","value":"Адапален+Метронидазол"},{"name":"Способ применения и дозы","value":"Наружно. Взрослым. Гель следует наносить тонким слоем на пораженные угревой сыпью участки кожи один раз в сутки перед сном на чистую сухую кожу, избегая попадания геля в глаза, на губы, слизистые оболочки и уголки носа. Заметное клиническое улучшение развивается после 4-8 недель лечения, стойкое улучшение после 3-х месячного курса лечения. Поскольку при лечении угревой сыпи принято чередование методов терапии, то через З месяца терапии препаратом рекомендуется проконсультироваться с врачом о дальнейшей терапии. Если после лечения улучшение не наступает или симптомы усугубляются, или появляются новые симптомы, необходимо проконсультироваться с врачом. Применяйте препарат только согласно тем показаниям, тому способу применения и в тех дозах, которые указаны в инструкции по применению."},{"name":"Побочные действия","value":"Частота развития побочных эффектов классифицирована согласно рекомендациям Всемирной организации здравоохранения: очень часто (\u003E 1/10), часто (\u003E 1/100, \u003C 1/10), нечасто (\u003E 1/1000, \u003C 1/100), редко (\u003E 1/10 000, \u003C 1/1000), очень редко (\u003C1/10 000), частота неизвестна: частота не может быть оценена на основании имеющихся данных.\u003Cbr /\u003EНарушения со стороны кожи и подкожных тканей: часто - сухость кожи, раздражение кожи, эритема, зуд, ощущение жжения кожи; нечасто - контактный дерматит, ощущение дискомфорта, солнечный ожог, шелушение кожи, угревая сыпь; частота неизвестна — аллергический дерматит (аллергический контактный дерматит), болезненность кожи, припухлость кожи, раздражение век, эритема век, зуд век, припухлость век, припухлость лица.\u003Cbr /\u003EНарушения со стороны нервной системы: нечасто - гипестезия, парастезия, дисгевзия\u003Cbr /\u003E(«металлический» привкус во рту).\u003Cbr /\u003EНарушения со стороны желуДочно-кишечного тракта: нечасто - тошнота.\u003Cbr /\u003EЕсли у Вас отмечаются побочные эффекты, указанные в инструкции, и они усугубляются, или Вы заметили любые Другие побочные эффекты, не указанные в инструкции, сообщите об этом врачу.\u003Cbr /\u003E"},{"name":"Фармакологическое действие","value":"Адапален — метаболит ретиноида, который действует на патологический механизм развития Аспе vulgaris, является сильным модулятором клеточной дифференцировки и кератинизации и обладает комедонолитической и противовоспалительной активностью. Механизм действия адапалена основан на взаимодействии со специфическими урецепторами эпидермальных клеток кожи. В результате действия адапалена происходит\u003Cbr /\u003Eснижение «сцепленности» эпителиальных клеток в устье сально-волосяного фолликула и уменьшение образования микрокомедонов. Адапален оказывает противовоспалительное действие in vivo и in vitro, воздействуя на факторы воспаления путем ингибирования миграции лейкоцитов в очаге воспаления, угнетает хемотактический и хемокинетический ответы полиморфноядерных лейкоцитов человека и подавляет метаболизм арахидоновой кислоты до медиаторов воспаления, АР-1 факторы и экспрессию ТоП-подобных рецепторов \u003Cbr /\u003EМетронидазол — противопротозойный и противомикробный препарат, производное 5нитроимидазола. Механизм действия заключается в биохимическом восстановлении 5нитрогруппы метронидазола внутриклеточными транспортными протеинами анаэробных микроорганизмов и простейших. Восстановленная 5-нитрогруппа метронидазола взаимодействует с ДНК клетки микроорганизмов, ингибируя синтез их нуклеиновых кислот, что ведет к гибели бактерий.\u003Cbr /\u003EАктивен в отношении Trichomonas vaginalis, Entamaeba histolytica, а также грамотрицательных анаэробов Bacteroides spp. (в т.ч. Bacteroides fragilis, Bacteroides distasonis, Bacteroides ovatus, Bacteroides thetaiotaomicron, Bacteroides vulgatus), Fusobacterium spp. и некоторых грамположительных анаэробов (чувствительные штаммы Eubacterium ,spp., Clostridium spp., Peptococcus niger, Peptostreptococcus spp.). Минимальная подавляющая концентрация (МПК) для этих штаммов составляет 0,1256,25 мкг/мл.\u003Cbr /\u003EК метронидазолу нечувствительны аэробные микроорганизмы и факультативные анаэробы, но в присутствии смешанной флоры (аэробы и анаэробы) метронидазол действует синергично с антибиотиками, эффективными против обычных аэробов.\u003Cbr /\u003E"},{"name":"Фармакологическая группа","value":"средство лечения угревой сыпи"},{"name":"Форма выпуска","value":"гель"},{"name":"Способ применения/введения","value":"наружный"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"При температуре не выше 30 ос, в оригинальной упаковке (туба в пачке). Не замораживать! Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Данные по передозировке препарата отсутствуют. При применении препарата в соответствии с инструкцией по применению передозировка маловероятна. При случайном проглатывании даже незначительного количества препарата, следует промыть желудок, при необходимости проводят симптоматическую терапию."},{"name":"Применение при беременности и кормлении грудью","value":"Противопоказано применение препарата при беременности и в период грудного вскармливания."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Препарат Метрогил А не оказывает влияния на способность управлять транспортными средствами и работать с механизмами."},{"name":"Особые указания","value":"С осторожностью При нарушениях со стороны крови, в том числе в анамнезе. \u003Cbr /\u003EНеобходимо тщательно вымыть руки до и после нанесения геля.\u003Cbr /\u003EВ случае возникновения реакций гиперчувствительности или выраженного раздражения применение препарата следует прекратить. В некоторых случаях, в зависимости от степени раздражения кожи, число нанесений может быть сокращено, лечение приостановлено до исчезновения признаков раздражения, либо прекращено. Следует избегать попадания геля в глаза, рот, уголки носа и на слизистые оболочки.\u003Cbr /\u003EВ случае попадания геля в глаза их следует незамедлительно промыть теплой водой. Препарат нельзя наносить на поврежденную в результате травмы (порезы или ссадины), солнечного ожога или экзематозную кожу. Кроме того, его не следует применять у пациентов с тяжелой формой угревой сыпи на обширных участках кожи.\u003Cbr /\u003EМетронидазол является производным нитроимидазола и его следует применять с осторожностью у пациентов с имеющимися в настоящее время либо отмечавшимися в анамнезе нарушениями со стороны крови.\u003Cbr /\u003EПри применении препарата Метрогил@ А следует избегать воздействия искусственного ультрафиолетового облучения (солярии, лампы солнечного света) и воздействия солнечного света (включая солнечные ванны). Под влиянием УФ-лучей метронидазол превращается в неактивный метаболит, в связи с чем возможно значимое снижение эффективности препарата. Если избежать воздействия не представляется возможным, рекомендуется применение солнцезащитных средств и одежды для защиты обработанных препаратом участков кожи.\u003Cbr /\u003EСледует избегать излишнего и длительного применения препарата.\u003Cbr /\u003EПрепарат содержит пропиленгликоль, который может вызывать раздражение кожи.\u003Cbr /\u003E"},{"name":"Взаимодействие","value":"Адапален\u003Cbr /\u003EНе установлено взаимодействий с другими лекарственными средствами, которые могут применяться наружно и одновременно с данным препаратом; тем не менее, одновременно с адапаленом не следует применять другие ретиноиды или препараты со сходным механизмом действия.\u003Cbr /\u003EВсасывание адапалена через кожу является низким, поэтому его взаимодействие с системными лекарственными препаратами маловероятно.\u003Cbr /\u003EОдновременное применение средств для пилинга, абразивных очищающих средств, а также средств с подсушивающим, вяжущим или раздражающим действием\u003Cbr /\u003E(ароматических или спиртсодержащих средств) не рекомендуется.\u003Cbr /\u003EМетронидазол\u003Cbr /\u003EПри применении геля не было зарегистрировано случаев взаимодействия с другими лекарственными средствами.\u003Cbr /\u003EВсасывание метронидазола через кожу является низким, поэтому его взаимодействие с системными лекарственными препаратами маловероятно.\u003Cbr /\u003EТем не менее следует учитывать, что у небольшого количества пациентов отмечались дисульфирамоподобные реакции при одновременном приеме метронидазола внутрь и этанола.\u003Cbr /\u003EПредупреждение соблюдать осторожность при одновременном применении метронидазола с варфарином или другими непрямыми антикоагулянтами из-за возможного удлинения протромбинового времени относится только к метронидазолу для приема внутрь.\u003Cbr /\u003EЕсли Вы применяете вышеперечисленные средства или другие лекарственные препараты (в том числе безрецептурные), перед применением препарата проконсультируйтесь с врачом.\u003Cbr /\u003E"},{"name":"Регистрационный номер","value":"ЛП-006281"},{"name":"Дата государственной регистрации","value":"22.06.2020"},{"name":"Владелец регистрационного удостоверения","value":"Unique Pharmaceuticals"},{"name":"Изготовитель","value":"Unique Pharmaceuticals"},{"name":"Страна бренда","value":"Индия"},{"name":"Страна-производитель","value":"Индия"},{"name":"Название препарата","value":"Метрогил"},{"name":"Срок годности","value":"36 мес."}]}],"transitionId":"tr_6"}}}}
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Применяйте препарат только согласно тем показаниям, тому способу применения и в тех дозах, которые указаны в инструкции по применению."},{"description":"","filters":[{"id":15767998,"name":"Побочные действия"}],"isMainProperty":false,"name":"Побочные действия","value":"Частота развития побочных эффектов классифицирована согласно рекомендациям Всемирной организации здравоохранения: очень часто (\u003E 1/10), часто (\u003E 1/100, \u003C 1/10), нечасто (\u003E 1/1000, \u003C 1/100), редко (\u003E 1/10 000, \u003C 1/1000), очень редко (\u003C1/10 000), частота неизвестна: частота не может быть оценена на основании имеющихся данных.\u003Cbr /\u003EНарушения со стороны кожи и подкожных тканей: часто - сухость кожи, раздражение кожи, эритема, зуд, ощущение жжения кожи; нечасто - контактный дерматит, ощущение дискомфорта, солнечный ожог, шелушение кожи, угревая сыпь; частота неизвестна — аллергический дерматит (аллергический контактный дерматит), болезненность кожи, припухлость кожи, раздражение век, эритема век, зуд век, припухлость век, припухлость лица.\u003Cbr /\u003EНарушения со стороны нервной системы: нечасто - гипестезия, парастезия, дисгевзия\u003Cbr /\u003E(«металлический» привкус во рту).\u003Cbr /\u003EНарушения со стороны желуДочно-кишечного тракта: нечасто - тошнота.\u003Cbr /\u003EЕсли у Вас отмечаются побочные эффекты, указанные в инструкции, и они усугубляются, или Вы заметили любые Другие побочные эффекты, не указанные в инструкции, сообщите об этом врачу.\u003Cbr /\u003E"},{"description":"","filters":[{"id":15768001,"name":"Фармакологическое действие"}],"isMainProperty":false,"name":"Фармакологическое действие","value":"Адапален — метаболит ретиноида, который действует на патологический механизм развития Аспе vulgaris, является сильным модулятором клеточной дифференцировки и кератинизации и обладает комедонолитической и противовоспалительной активностью. Механизм действия адапалена основан на взаимодействии со специфическими урецепторами эпидермальных клеток кожи. В результате действия адапалена происходит\u003Cbr /\u003Eснижение «сцепленности» эпителиальных клеток в устье сально-волосяного фолликула и уменьшение образования микрокомедонов. Адапален оказывает противовоспалительное действие in vivo и in vitro, воздействуя на факторы воспаления путем ингибирования миграции лейкоцитов в очаге воспаления, угнетает хемотактический и хемокинетический ответы полиморфноядерных лейкоцитов человека и подавляет метаболизм арахидоновой кислоты до медиаторов воспаления, АР-1 факторы и экспрессию ТоП-подобных рецепторов \u003Cbr /\u003EМетронидазол — противопротозойный и противомикробный препарат, производное 5нитроимидазола. Механизм действия заключается в биохимическом восстановлении 5нитрогруппы метронидазола внутриклеточными транспортными протеинами анаэробных микроорганизмов и простейших. Восстановленная 5-нитрогруппа метронидазола взаимодействует с ДНК клетки микроорганизмов, ингибируя синтез их нуклеиновых кислот, что ведет к гибели бактерий.\u003Cbr /\u003EАктивен в отношении Trichomonas vaginalis, Entamaeba histolytica, а также грамотрицательных анаэробов Bacteroides spp. (в т.ч. Bacteroides fragilis, Bacteroides distasonis, Bacteroides ovatus, Bacteroides thetaiotaomicron, Bacteroides vulgatus), Fusobacterium spp. и некоторых грамположительных анаэробов (чувствительные штаммы Eubacterium ,spp., Clostridium spp., Peptococcus niger, Peptostreptococcus spp.). 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В некоторых случаях, в зависимости от степени раздражения кожи, число нанесений может быть сокращено, лечение приостановлено до исчезновения признаков раздражения, либо прекращено. Следует избегать попадания геля в глаза, рот, уголки носа и на слизистые оболочки.\u003Cbr /\u003EВ случае попадания геля в глаза их следует незамедлительно промыть теплой водой. Препарат нельзя наносить на поврежденную в результате травмы (порезы или ссадины), солнечного ожога или экзематозную кожу. Кроме того, его не следует применять у пациентов с тяжелой формой угревой сыпи на обширных участках кожи.\u003Cbr /\u003EМетронидазол является производным нитроимидазола и его следует применять с осторожностью у пациентов с имеющимися в настоящее время либо отмечавшимися в анамнезе нарушениями со стороны крови.\u003Cbr /\u003EПри применении препарата Метрогил@ А следует избегать воздействия искусственного ультрафиолетового облучения (солярии, лампы солнечного света) и воздействия солнечного света (включая солнечные ванны). Под влиянием УФ-лучей метронидазол превращается в неактивный метаболит, в связи с чем возможно значимое снижение эффективности препарата. 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  • Метрогил гель д/нар. прим., 1%, 30 мл, 30 г
    –1 %
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    Метрогил гель д/нар. прим., 1%, 30 мл, 30 г

    Рейтинг товара: 4.4 из 5
    на основе 35 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 334 ₽ вместо 337
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  • Азелик гель д/нар. прим., 15%, 30 мл, 30 г
    ВАМ–9 %
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    Азелик гель д/нар. прим., 15%, 30 мл, 30 г

    Рейтинг товара: 4.8 из 5
    на основе 74 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 912 ₽ вместо 921
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  • Розамет крем, 1%, 25 мл, 25 г
    –2 %
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    Розамет крем, 1%, 25 мл, 25 г

    Рейтинг товара: 4.3 из 5
    на основе 7 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 412 ₽ вместо 420
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  • Клиндовит Комбо гель д/нар.прим, 50 мг+10 мг/г, 15 г
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    Клиндовит Комбо гель д/нар.прим, 50 мг+10 мг/г, 15 г

    Рейтинг товара: 4.8 из 5
    на основе 4 оценки
    Цена 671 ₽
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  • Скиноклир крем д/нар.прим. туба, 20%, 30 г
    –1 %
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    Скиноклир крем д/нар.прим. туба, 20%, 30 г

    Рейтинг товара: 4.8 из 5
    на основе 47 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 775 ₽ вместо 783
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  • Метронидазол гель д/нар. прим., 1%, 30 мл, 30 г
    –1 %
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    Метронидазол гель д/нар. прим., 1%, 30 мл, 30 г

    Рейтинг товара: 5 из 5
    на основе 3 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 169 ₽ вместо 171
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  • Клензит гель д/нар. прим., 15 г
    –1 %
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    Клензит гель д/нар. прим., 15 г

    Рейтинг товара: 5 из 5
    на основе 9 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 751 ₽ вместо 759
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  • Зеркалин Интенсив гель д/нар. прим., 50 мг+10 мг/г, 30 мл, 25 г
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    Зеркалин Интенсив гель д/нар. прим., 50 мг+10 мг/г, 30 мл, 25 г

    Рейтинг товара: 4.9 из 5
    на основе 24 оценки
    Цена 943 ₽
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  • Левомеколь мазь д/нар. прим., 40 мг/г+7.5 мг/г, 40 мл, 40 г
    –1 %
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    Левомеколь мазь д/нар. прим., 40 мг/г+7.5 мг/г, 40 мл, 40 г

    Рейтинг товара: 4.8 из 5
    на основе 123 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 220 ₽ вместо 222
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  • Куриозин гель д/нар. прим., 0.103%, 15 г, 1 шт.
    –1 %
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    Куриозин гель д/нар. прим., 0.103%, 15 г, 1 шт.

    Рейтинг товара: 5 из 5
    на основе 28 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 787 ₽ вместо 795
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Инструкция

Показания к применению

Угревая сыпь легкой и средней степени тяжести, в том числе при наличии комедонов, папул и пустул, с локализацией на коже лица, груди или спины.

Противопоказания

Повышенная чувствительность к адапалену, метронидазолу, производным нитроимидазола, имидазолам или любому из вспомогательных веществ. Детский возраст до 18 лет (эффективность и безопасность препарата для данной возрастной категории не установлена). Беременность, период грудного вскармливания.

Способ применения и дозы

Наружно. Взрослым. Гель следует наносить тонким слоем на пораженные угревой сыпью участки кожи один раз в сутки перед сном на чистую сухую кожу, избегая попадания геля в глаза, на губы, слизистые оболочки и уголки носа. Заметное клиническое улучшение развивается после 4-8 недель лечения, стойкое улучшение после 3-х месячного курса лечения. Поскольку при лечении угревой сыпи принято чередование методов терапии, то через З месяца терапии препаратом рекомендуется проконсультироваться с врачом о дальнейшей терапии. Если после лечения улучшение не наступает или симптомы усугубляются, или появляются новые симптомы, необходимо проконсультироваться с врачом. Применяйте препарат только согласно тем показаниям, тому способу применения и в тех дозах, которые указаны в инструкции по применению.
Полная инструкция
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Метрогил А гель д/нар. прим.
Метрогил А гель д/нар. прим., 0.1%, 20 г
4.3
(4)
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1 вопрос
Инструкция

Цена с картой Яндекс Пэй:675 ₽

Скидка: 2%
–2 %
Вместо: 689 ₽
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4.3
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У продавца:4 оценки·2 отзыва
У всех продавцов:37 оценок·12 отзывов
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user avatar
11 месяцев назад • Имя скрыто • Куплен на Маркете
Достоинства: хорошо сужает поры
Недостатки: острожно, пересушивает кожу, наносить точечно
Комментарий: после первого приема поры стали менее заметны, убирает воспаление. наносить тонким слоем или точечно, может пересушить кожу.
user avatar
5 месяцев назад • Валерия Кончакова • Куплен на Маркете
Комментарий: Не увидела результатов на коже с акне.. немного сушит и вызывает шелушение, как и все ретиноиды, но воспаления не прошли и даже стали больше. Пользуюсь уже 3 месяца.. не мое средство. Сейчас наношу точечно на воспаления, но вообще не вижу,чтобы как-то способствовала мазь заживлению/убавлению воспаления
Посмотреть все отзывы на Маркете
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    Клензит-C гель д/нар. прим., 30 г

    Цена 1 298 ₽ вместо 1 311
  • Метрогил Дента стомат. гель туба, 20 г
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    Метрогил Дента стомат. гель туба, 20 г

    Цена 403 ₽ вместо 407
  • Клиндовит гель д/нар. прим., 1%, 30 г
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    Клиндовит гель д/нар. прим., 1%, 30 г

    Цена 491 ₽ вместо 496
  • Vitamin D3, 10000 МЕ, 120 шт.
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    Vitamin D3, 10000 МЕ, 120 шт.

    Цена 1 091 ₽ вместо 2 290
  • Сорбифер дурулес таб. п/о, 30 шт.
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    Сорбифер дурулес таб. п/о, 30 шт.

    Цена 707 ₽
  • Жидкий пластырь Fixplast c пантенолом, 60 мл
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    Жидкий пластырь Fixplast c пантенолом, 60 мл

    Цена 303 ₽ вместо 399
  • Кето плюс шампунь, 60 мл, 1 шт.
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    Кето плюс шампунь, 60 мл, 1 шт.

    Цена 1 129 ₽ вместо 1 140
  • Реклама
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  • Крем для лица и тела после загара MIXIT "BACK TO SUN" защитный, увлажняющий, с пантенолом и алоэ вера, 150 мл
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    Крем для лица и тела после загара MIXIT "BACK TO SUN" защитный, увлажняющий, с пантенолом и алоэ вера, 150 мл

    Цена 194 ₽ вместо 604
  • Акриол Про крем д/мест. и нар. прим., 2,5%+2,5%, 5 г
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    Акриол Про крем д/мест. и нар. прим., 2,5%+2,5%, 5 г

    Цена 300 ₽ вместо 303
  • Азелик гель д/нар. прим., 15%, 30 мл, 30 г
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    Азелик гель д/нар. прим., 15%, 30 мл, 30 г

    Цена 912 ₽ вместо 1 003
  • Розамет крем, 1%, 25 мл, 25 г
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    Розамет крем, 1%, 25 мл, 25 г

    Цена 360 ₽ вместо 364
  • Клиндовит Комбо гель д/нар.прим, 50 мг+10 мг/г, 15 г
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    Клиндовит Комбо гель д/нар.прим, 50 мг+10 мг/г, 15 г

    Цена 671 ₽
  • ЛимфоТранзит концентрат напитка фл., 100 мл
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    ЛимфоТранзит концентрат напитка фл., 100 мл

    Цена 332 ₽ вместо 390
  • Кетоконазол шампунь лекарственный, 2%, 75 г
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    Кетоконазол шампунь лекарственный, 2%, 75 г

    Цена 296 ₽ вместо 299
  • Гилан Комфорт увлажн. гл. р-р, 0.18%, 0.4 мл, 30 шт.
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    Гилан Комфорт увлажн. гл. р-р, 0.18%, 0.4 мл, 30 шт.

    Цена 449 ₽
  • Белосалик лосьон фл. с распыл., 50 мл
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    Белосалик лосьон фл. с распыл., 50 мл

    Цена 765 ₽ вместо 773
  • Скиноклир крем д/нар.прим. туба, 20%, 30 г
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    Скиноклир крем д/нар.прим. туба, 20%, 30 г

    Цена 775 ₽ вместо 783
  • Холисал стомат. гель, 10 г
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    Холисал стомат. гель, 10 г

    Цена 456 ₽ вместо 461
  • Метронидазол гель д/нар. прим., 1%, 30 мл, 30 г
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    Метронидазол гель д/нар. прим., 1%, 30 мл, 30 г

    Цена 169 ₽ вместо 171
  • Реклама
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  • Клензит гель д/нар. прим., 15 г
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    Клензит гель д/нар. прим., 15 г

    Цена 751 ₽ вместо 759
  • Зеркалин Интенсив гель д/нар. прим., 50 мг+10 мг/г, 30 мл, 25 г
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    Зеркалин Интенсив гель д/нар. прим., 50 мг+10 мг/г, 30 мл, 25 г

    Цена 943 ₽
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