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Описание

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Мидокалм таб. п/о плен., 50 мг, 30 шт.

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4.9
(40)
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Коротко о товаре

Артикул Маркета
517970241
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
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кремния диоксид коллоидный; стеариновая кислота; тальк; целлюлоза микрокристаллическая тип 102; крахмал кукурузный; лактозы моногидрат.\u003Cbr\u003EСостав пленочной оболочки: кремния диоксид коллоидный; титана диоксид Е 171; лактозы моногидрат; макрогол 6000; гипромеллоза.\u003Cbr\u003E"},{"name":"Действующее вещество","value":"Толперизон","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["27144131:28710499"]}}},{"name":"Способ применения и дозы","value":"Внутрь после еды, запивая стаканом воды.\u003Cbr /\u003EБиодоступность толперизона снижается при приеме натощак.\u003Cbr /\u003EДоза препарата подбирается исходя из индивидуальной потребности пациента и переносимости препарата.\u003Cbr /\u003EВзрослые и поДростки старше 14 лет\u003Cbr /\u003EРекомендованная суточная доза в зависимости от индивидуальной потребности и переносимости препарата пациентом составляет 150 — 450 мг, разделенная на З приема.\u003Cbr /\u003EПациенты с почечной недостаточностью\u003Cbr /\u003EОпыт применения толперизона у пациентов с почечной недостаточностью ограничен, у данной категории пациентов чаще возникали нежелательные реакции. Поэтому у пациентов с нарушениями функции почек средней степени необходимо проводить подбор дозы толперизона с тщательным наблюдением за состоянием здоровья пациента и контролем функции почек. При тяжелом поражении почек назначение толперизона не рекомендуется.\u003Cbr /\u003EПациенты с печеночной недостаточностью\u003Cbr /\u003EОпыт применения толперизона у пациентов с печеночной недостаточностью ограничен, у данной категории пациентов чаще возникали нежелательные реакции. Поэтому у пациентов с нарушениями функции печени средней степени необходимо проводить подбор дозы толперизона с тщательным наблюдением за состоянием здоровья пациента и контролем функции печени. При тяжелом поражении печени назначение толперизона не рекомендуется.\u003Cbr /\u003EПрименение у Детей\u003Cbr /\u003EДети от З до 6 лет: препарат назначается внутрь в суточной дозе 5 мг/кг массы тела, распределенной на З приема.\u003Cbr /\u003EДети и подростки от 7 до 14 лет: препарат назначается внутрь в суточной дозе 2 — 4 мг/кг, распределенной на З приема.\u003Cbr /\u003EУчитывая малую величину доз, детям следует назначать препарат в виде таблеток, покрытых пленочной оболочкой, 50 мг."},{"name":"Побочные действия","value":"Профиль безопасности толперизона оценивался по данным постмаркетингового применения более чем у 12 000 пациентов.\u003Cbr\u003EВ соответствии с этими данными наиболее частыми были нарушения со стороны кожи и подкожных тканей, общие расстройства, нарушения со стороны нервной системы и желудочно-кишечного тракта.\u003Cbr\u003EПри постмаркетинговом применении реакции гиперчувствительности составили 50 - 60% всех побочных реакций. Большинство побочных реакций не были серьезными и проходили самостоятельно. Жизнеугрожающие реакции гиперчувствительности регистрировались очень редко.\u003Cbr\u003EПобочные реакции приведены ниже в соответствии с классификацией MedDRA и частотой: нечасто (от \u003E1/1 000 до \u003C1/100); редко (от \u003E1/10 000 до \u003C1/1 000); очень редко (\u003C1/10 000); частота неизвестна (невозможно оценить на основании имеющихся данных).\u003Cbr\u003EНарушения со стороны крови и лимфатической системы\u003Cbr\u003EОчень редко: анемия, лимфаденопатия.\u003Cbr\u003EНарушения со стороны иммунной системы\u003Cbr\u003EРедко: реакция гиперчувствительности, анафилактическая реакция; Очень редко: анафилактический шок; Частота неизвестна: ангионевротический отек, включая отек лица, губ.\u003Cbr\u003EНарушения со стороны обмена веществ и питания\u003Cbr\u003EНечасто: анорексия; Очень редко: полидипсия.\u003Cbr\u003EНарушения психики\u003Cbr\u003EНечасто: бессонница, нарушения сна; Редко: снижение активности, депрессия; Очень редко: спутанность сознания.\u003Cbr\u003EНарушения со стороны нервной системы\u003Cbr\u003EНечасто: головная боль, головокружение, сонливость; Редко: нарушение внимания, тремор, эпилепсия, гипестезия, парестезия, летаргия.\u003Cbr\u003EНарушения со стороны органа зрения\u003Cbr\u003EРедко: нечеткость зрения.\u003Cbr\u003EНарушения со стороны органа слуха и лабиринтные нарушения\u003Cbr\u003EРедко: шум в ушах, вертиго.\u003Cbr\u003EНарушения со стороны сердца\u003Cbr\u003EРедко: стенокардия, тахикардия, ощущение сердцебиения; Очень редко: брадикардия.\u003Cbr\u003EНарушения со стороны сосудов\u003Cbr\u003EНечасто: артериальная гипотензия; Редко: «приливы».\u003Cbr\u003EНарушения со стороны дыхательной системы, органов грудной клетки и средостения\u003Cbr\u003EРедко: одышка, носовое кровотечение, учащенное дыхание.\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта\u003Cbr\u003EНечасто: дискомфорт в животе, диарея, сухость во рту, диспепсия, тошнота; Редко: боль в эпигастральной области, запор, метеоризм, рвота.\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей\u003Cbr\u003EРедко: печеночная недостаточность легкой степени.\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей\u003Cbr\u003EРедко: аллергический дерматит, повышенная потливость, зуд, крапивница, сыпь.\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей\u003Cbr\u003EРедко: энурез, протеинурия.\u003Cbr\u003EНарушения со стороны скелетно-мышечной и соединительной ткани\u003Cbr\u003EНечасто: мышечная слабость, миалгия, боль в конечностях; Редко: дискомфорт в конечностях; Очень редко: остеопения.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения\u003Cbr\u003EНечасто: астения, дискомфорт, усталость; Редко: чувство опьянения, чувство жара, раздражительность, жажда; Очень редко: дискомфорт в грудной клетке.\u003Cbr\u003EЛабораторные и инструментальные данные\u003Cbr\u003EРедко: снижение артериального давления, гипербилирубинемия, изменение активности печеночных ферментов, тромбоцитопения, лейкоцитоз; Очень редко: увеличение концентрации креатинина в плазме крови.\u003Cbr\u003EЕсли любые из указанных в инструкции нежелательных реакций усугубляются, или Вы заметили любые другие нежелательные реакции, не указанные в инструкции, сообщите об этом лечащему врачу.\u003Cbr\u003E"},{"name":"Фармакологическое действие","value":"Толперизон является миорелаксантом центрального действия. Точный механизм действия полностью не выяснен. Толперизон обладает высокой аффинностью к нервной ткани, достигая наибольших концентраций в стволе головного мозга, спинном мозге и периферической нервной системе. Основной эффект толперизона опосредован торможением спинальных рефлекторных дуг. Вероятно, этот эффект совместно с устранением облегчения проведения возбуждения по нисходящим путям обеспечивает терапевтическое воздействие толперизона.\u003Cbr\u003EХимическая структура толперизона схожа со структурой лидокаина. Подобно лидокаину, он обладает мембраностабилизирующим действием и снижает электрическую возбудимость двигательных нейронов и первичных афферентных волокон. Толперизон дозозависимо тормозит активность потенциалзависимых натриевых каналов.\u003Cbr\u003EСоответственно, снижается амплитуда и частота потенциала действия.\u003Cbr\u003EБыл доказан угнетающий эффект на потенциалзависимые кальциевые каналы.\u003Cbr\u003EПредполагается, что в дополнение к его мембраностабилизирующему действию толперизон может также тормозить выброс медиатора. Толперизон обладает некоторыми слабыми свойствами альфа-адренергических антагонистов и антимускариновым действием.\u003Cbr\u003E"},{"name":"Фармакологическая группа","value":"миорелаксант центрального действия"},{"name":"Форма выпуска","value":"таблетки, покрытые пленочной оболочкой"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"При температуре не выше 25°С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы передозировки чаще всего включают: сонливость, желудочно-кишечные\u003Cbr\u003Eнарушения (тошнота, рвота, боль в эпигастрии), тахикардия, повышение артериального давления, брадикинезия и вертиго. В тяжелых случаях судороги, угнетение дыхания, апноэ\u003Cbr\u003Eи кома.\u003Cbr\u003EЛечение: специфического антидота нет, рекомендована симптоматическая терапия.\u003Cbr\u003E"},{"name":"Применение при беременности и кормлении грудью","value":"Беременность\u003Cbr\u003EВ экспериментальных исследованиях на животных не выявлено тератогенного действия толперизона. По причине отсутствия значимых клинических данных толперизон не следует применять при беременности, за исключением случаев, когда ожидаемая польза определенно оправдывает потенциальный риск для плода.\u003Cbr\u003EПериод грудного вскармливания Поскольку данные о выделении толперизона с грудным молоком отсутствуют, то его применение в период кормления грудью противопоказано.\u003Cbr\u003E"},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Толперизон не оказывает влияния на способность к управлению транспортными средствами и механизмами. Пациентам, у которых есть головокружение, сонливость, нарушение внимания, эпилепсия, нечеткость зрения или мышечная слабость во время приема толперизона, следует проконсультироваться с врачом."},{"name":"Особые указания","value":"С осторожностью\nПрепарат следует применять с осторожностью у женщин, пациентов с гиперчувствительностью к лидокаину и/или другим препаратам или с аллергией в анамнезе (см. раздел «Особые указания»), у пациентов с почечной и печеночной недостаточностью (см. раздел «Способ применения и дозы»).\u003Cbr\u003EЕсли у Вас имеется какое-либо из вышеперечисленных состояний/заболеваний перед приемом препарата обязательно проконсультируйтесь с врачом.\u003Cbr\u003EНаиболее частыми нежелательными реакциями при применении толперизона в пострегистрационном периоде были реакции гиперчувствительности. Их выраженность варьирует от легких кожных реакций до тяжелых системных реакций, включая анафилактический шок. Симптомами реакций гиперчувствительности могут быть эритема, сыпь, крапивница, зуд, ангионевротический отек, тахикардия, артериальная гипотензия или одышка.\u003Cbr\u003EЖенщины и пациенты с повышенной чувствительностью к другим препаратам или с аллергией в анамнезе могут быть подвержены более высокому риску гиперчувствительности к толперизону.\u003Cbr\u003EВ случае известной гиперчувствительности к лидокаину при применении толперизона следует соблюдать повышенную осторожность из-за возможных перекрестных реакций.\u003Cbr\u003EНеобходимо рекомендовать пациентам иметь настороженность в отношении возможных симптомов аллергии. Пациенты должны быть осведомлены о том, что при появлении симптомов аллергии следует прекратить прием толперизона и немедленно обратиться за медицинской помощью.\u003Cbr\u003EПосле эпизода гиперчувствительности к толперизону повторно назначать препарат нельзя.\u003Cbr\u003EПрепарат Мидокалм к содержит лактозы моногидрат. Пациентам с редкой наследственной непереносимостью галактозы, недостаточностью лактазы и глюкозо-галактозной мальабсорбцией не следует принимать Мидокалм.\u003Cbr\u003E"},{"name":"Взаимодействие","value":"В фармакокинетических исследованиях лекарственных взаимодействий установлено, что совместный прием толперизона с субстратом изофермента CYP2D6 декстраметорфаном способствует увеличению концентрации в крови средств, которые метаболизируются преимущественно изоферментом CYP2D6, например, тиоридазина, толтеродина, венлафаксина, атомоксетина, дезипрамина, декстрометорфана, метопролола, небиволола и\u003Cbr\u003Eперфеназина.\u003Cbr\u003EВ исследованиях in vitro на микросомах печени человека и гепатоцитах человека выраженное ингибирование или индукция других изоферментов (CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP1A2, CYP3A4) не подтверждены.\u003Cbr\u003EПовышение экспозиции толперизона не ожидается после одновременного введения субстратов изофермента CYP2D6 и/или других препаратов из-за разнообразия метаболических путей толперизона.\u003Cbr\u003EБиодоступность толперизона снижается при приеме натощак, поэтому применение препарата рекомендуется после приема пищи.\u003Cbr\u003EХотя толперизон влияет на центральную нервную систему, его потенциальный седативный эффект низкий. В случае совместного приема с другими миорелаксантами центрального действия следует оценить необходимость снижения дозы толперизона.\u003Cbr\u003EТолперизон усиливает действие нифлумовой кислоты, поэтому следует уменьшить дозу нифлумовой кислоты или другого НПВП в случае одновременного применения с толперизоном.\u003Cbr\u003E"},{"name":"Регистрационный номер","value":"P N002409/01"},{"name":"Дата государственной регистрации","value":"02.08.2022"},{"name":"Владелец регистрационного удостоверения","value":"Гедеон Рихтер ОАО","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["34324371:35649313","7893318:17672958"]}}},{"name":"Изготовитель","value":"Гедеон Рихтер-РУС"},{"name":"Страна бренда","value":"Венгрия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Мидокалм","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["17796364:18035497"]}}},{"name":"Срок годности","value":"855 дн."}]}},"fullSpecsGrouped":{"16682927530534743960":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"опорно-двигательная система"},{"name":"Назначение","value":"болевой синдром средней и высокой интенсивности различной этиологии, мышечные боли и спазмы"},{"name":"Показания к применению","value":"Симптоматическое лечение спастичности у взрослых, обусловленной инсультом.\u003Cbr\u003EМиофасциальный болевой синдром средней и тяжелой степени (в том числе мышечный спазм при дорсопатиях)."},{"name":"Противопоказания","value":"- гиперчувствительность к любому из компонентов препарата или химически сходному\u003Cbr\u003EЭперизону;\u003Cbr\u003E- миастения gravis;\u003Cbr\u003E- беременность и период грудного вскармливания;\u003Cbr\u003E- детский возраст до 18 лет;\u003Cbr\u003E- непереносимость галактозы, лактазная недостаточность, глюкозо-галактозная мальабсорбция.\u003Cbr\u003E"},{"name":"Состав","value":"1 таблетка, покрытая пленочной оболочкой, содержит:\u003Cbr\u003EДействующее вещество: толперизона гидрохлорид 50 мг и 150 мг.\u003Cbr\u003EВспомогательные вещества: лимонной кислоты моногидрат; кремния диоксид коллоидный; стеариновая кислота; тальк; целлюлоза микрокристаллическая тип 102; крахмал кукурузный; лактозы моногидрат.\u003Cbr\u003EСостав пленочной оболочки: кремния диоксид коллоидный; титана диоксид Е 171; лактозы моногидрат; макрогол 6000; гипромеллоза.\u003Cbr\u003E"},{"name":"Действующее вещество","value":"Толперизон"},{"name":"Способ применения и дозы","value":"Внутрь после еды, запивая стаканом воды.\u003Cbr /\u003EБиодоступность толперизона снижается при приеме натощак.\u003Cbr /\u003EДоза препарата подбирается исходя из индивидуальной потребности пациента и переносимости препарата.\u003Cbr /\u003EВзрослые и поДростки старше 14 лет\u003Cbr /\u003EРекомендованная суточная доза в зависимости от индивидуальной потребности и переносимости препарата пациентом составляет 150 — 450 мг, разделенная на З приема.\u003Cbr /\u003EПациенты с почечной недостаточностью\u003Cbr /\u003EОпыт применения толперизона у пациентов с почечной недостаточностью ограничен, у данной категории пациентов чаще возникали нежелательные реакции. Поэтому у пациентов с нарушениями функции почек средней степени необходимо проводить подбор дозы толперизона с тщательным наблюдением за состоянием здоровья пациента и контролем функции почек. При тяжелом поражении почек назначение толперизона не рекомендуется.\u003Cbr /\u003EПациенты с печеночной недостаточностью\u003Cbr /\u003EОпыт применения толперизона у пациентов с печеночной недостаточностью ограничен, у данной категории пациентов чаще возникали нежелательные реакции. Поэтому у пациентов с нарушениями функции печени средней степени необходимо проводить подбор дозы толперизона с тщательным наблюдением за состоянием здоровья пациента и контролем функции печени. При тяжелом поражении печени назначение толперизона не рекомендуется.\u003Cbr /\u003EПрименение у Детей\u003Cbr /\u003EДети от З до 6 лет: препарат назначается внутрь в суточной дозе 5 мг/кг массы тела, распределенной на З приема.\u003Cbr /\u003EДети и подростки от 7 до 14 лет: препарат назначается внутрь в суточной дозе 2 — 4 мг/кг, распределенной на З приема.\u003Cbr /\u003EУчитывая малую величину доз, детям следует назначать препарат в виде таблеток, покрытых пленочной оболочкой, 50 мг."},{"name":"Побочные действия","value":"Профиль безопасности толперизона оценивался по данным постмаркетингового применения более чем у 12 000 пациентов.\u003Cbr\u003EВ соответствии с этими данными наиболее частыми были нарушения со стороны кожи и подкожных тканей, общие расстройства, нарушения со стороны нервной системы и желудочно-кишечного тракта.\u003Cbr\u003EПри постмаркетинговом применении реакции гиперчувствительности составили 50 - 60% всех побочных реакций. Большинство побочных реакций не были серьезными и проходили самостоятельно. Жизнеугрожающие реакции гиперчувствительности регистрировались очень редко.\u003Cbr\u003EПобочные реакции приведены ниже в соответствии с классификацией MedDRA и частотой: нечасто (от \u003E1/1 000 до \u003C1/100); редко (от \u003E1/10 000 до \u003C1/1 000); очень редко (\u003C1/10 000); частота неизвестна (невозможно оценить на основании имеющихся данных).\u003Cbr\u003EНарушения со стороны крови и лимфатической системы\u003Cbr\u003EОчень редко: анемия, лимфаденопатия.\u003Cbr\u003EНарушения со стороны иммунной системы\u003Cbr\u003EРедко: реакция гиперчувствительности, анафилактическая реакция; Очень редко: анафилактический шок; Частота неизвестна: ангионевротический отек, включая отек лица, губ.\u003Cbr\u003EНарушения со стороны обмена веществ и питания\u003Cbr\u003EНечасто: анорексия; Очень редко: полидипсия.\u003Cbr\u003EНарушения психики\u003Cbr\u003EНечасто: бессонница, нарушения сна; Редко: снижение активности, депрессия; Очень редко: спутанность сознания.\u003Cbr\u003EНарушения со стороны нервной системы\u003Cbr\u003EНечасто: головная боль, головокружение, сонливость; Редко: нарушение внимания, тремор, эпилепсия, гипестезия, парестезия, летаргия.\u003Cbr\u003EНарушения со стороны органа зрения\u003Cbr\u003EРедко: нечеткость зрения.\u003Cbr\u003EНарушения со стороны органа слуха и лабиринтные нарушения\u003Cbr\u003EРедко: шум в ушах, вертиго.\u003Cbr\u003EНарушения со стороны сердца\u003Cbr\u003EРедко: стенокардия, тахикардия, ощущение сердцебиения; Очень редко: брадикардия.\u003Cbr\u003EНарушения со стороны сосудов\u003Cbr\u003EНечасто: артериальная гипотензия; Редко: «приливы».\u003Cbr\u003EНарушения со стороны дыхательной системы, органов грудной клетки и средостения\u003Cbr\u003EРедко: одышка, носовое кровотечение, учащенное дыхание.\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта\u003Cbr\u003EНечасто: дискомфорт в животе, диарея, сухость во рту, диспепсия, тошнота; Редко: боль в эпигастральной области, запор, метеоризм, рвота.\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей\u003Cbr\u003EРедко: печеночная недостаточность легкой степени.\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей\u003Cbr\u003EРедко: аллергический дерматит, повышенная потливость, зуд, крапивница, сыпь.\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей\u003Cbr\u003EРедко: энурез, протеинурия.\u003Cbr\u003EНарушения со стороны скелетно-мышечной и соединительной ткани\u003Cbr\u003EНечасто: мышечная слабость, миалгия, боль в конечностях; Редко: дискомфорт в конечностях; Очень редко: остеопения.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения\u003Cbr\u003EНечасто: астения, дискомфорт, усталость; Редко: чувство опьянения, чувство жара, раздражительность, жажда; Очень редко: дискомфорт в грудной клетке.\u003Cbr\u003EЛабораторные и инструментальные данные\u003Cbr\u003EРедко: снижение артериального давления, гипербилирубинемия, изменение активности печеночных ферментов, тромбоцитопения, лейкоцитоз; Очень редко: увеличение концентрации креатинина в плазме крови.\u003Cbr\u003EЕсли любые из указанных в инструкции нежелательных реакций усугубляются, или Вы заметили любые другие нежелательные реакции, не указанные в инструкции, сообщите об этом лечащему врачу.\u003Cbr\u003E"},{"name":"Фармакологическое действие","value":"Толперизон является миорелаксантом центрального действия. Точный механизм действия полностью не выяснен. Толперизон обладает высокой аффинностью к нервной ткани, достигая наибольших концентраций в стволе головного мозга, спинном мозге и периферической нервной системе. Основной эффект толперизона опосредован торможением спинальных рефлекторных дуг. Вероятно, этот эффект совместно с устранением облегчения проведения возбуждения по нисходящим путям обеспечивает терапевтическое воздействие толперизона.\u003Cbr\u003EХимическая структура толперизона схожа со структурой лидокаина. Подобно лидокаину, он обладает мембраностабилизирующим действием и снижает электрическую возбудимость двигательных нейронов и первичных афферентных волокон. Толперизон дозозависимо тормозит активность потенциалзависимых натриевых каналов.\u003Cbr\u003EСоответственно, снижается амплитуда и частота потенциала действия.\u003Cbr\u003EБыл доказан угнетающий эффект на потенциалзависимые кальциевые каналы.\u003Cbr\u003EПредполагается, что в дополнение к его мембраностабилизирующему действию толперизон может также тормозить выброс медиатора. Толперизон обладает некоторыми слабыми свойствами альфа-адренергических антагонистов и антимускариновым действием.\u003Cbr\u003E"},{"name":"Фармакологическая группа","value":"миорелаксант центрального действия"},{"name":"Форма выпуска","value":"таблетки, покрытые пленочной оболочкой"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"При температуре не выше 25°С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы передозировки чаще всего включают: сонливость, желудочно-кишечные\u003Cbr\u003Eнарушения (тошнота, рвота, боль в эпигастрии), тахикардия, повышение артериального давления, брадикинезия и вертиго. В тяжелых случаях судороги, угнетение дыхания, апноэ\u003Cbr\u003Eи кома.\u003Cbr\u003EЛечение: специфического антидота нет, рекомендована симптоматическая терапия.\u003Cbr\u003E"},{"name":"Применение при беременности и кормлении грудью","value":"Беременность\u003Cbr\u003EВ экспериментальных исследованиях на животных не выявлено тератогенного действия толперизона. По причине отсутствия значимых клинических данных толперизон не следует применять при беременности, за исключением случаев, когда ожидаемая польза определенно оправдывает потенциальный риск для плода.\u003Cbr\u003EПериод грудного вскармливания Поскольку данные о выделении толперизона с грудным молоком отсутствуют, то его применение в период кормления грудью противопоказано.\u003Cbr\u003E"},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Толперизон не оказывает влияния на способность к управлению транспортными средствами и механизмами. Пациентам, у которых есть головокружение, сонливость, нарушение внимания, эпилепсия, нечеткость зрения или мышечная слабость во время приема толперизона, следует проконсультироваться с врачом."},{"name":"Особые указания","value":"С осторожностью\nПрепарат следует применять с осторожностью у женщин, пациентов с гиперчувствительностью к лидокаину и/или другим препаратам или с аллергией в анамнезе (см. раздел «Особые указания»), у пациентов с почечной и печеночной недостаточностью (см. раздел «Способ применения и дозы»).\u003Cbr\u003EЕсли у Вас имеется какое-либо из вышеперечисленных состояний/заболеваний перед приемом препарата обязательно проконсультируйтесь с врачом.\u003Cbr\u003EНаиболее частыми нежелательными реакциями при применении толперизона в пострегистрационном периоде были реакции гиперчувствительности. Их выраженность варьирует от легких кожных реакций до тяжелых системных реакций, включая анафилактический шок. Симптомами реакций гиперчувствительности могут быть эритема, сыпь, крапивница, зуд, ангионевротический отек, тахикардия, артериальная гипотензия или одышка.\u003Cbr\u003EЖенщины и пациенты с повышенной чувствительностью к другим препаратам или с аллергией в анамнезе могут быть подвержены более высокому риску гиперчувствительности к толперизону.\u003Cbr\u003EВ случае известной гиперчувствительности к лидокаину при применении толперизона следует соблюдать повышенную осторожность из-за возможных перекрестных реакций.\u003Cbr\u003EНеобходимо рекомендовать пациентам иметь настороженность в отношении возможных симптомов аллергии. Пациенты должны быть осведомлены о том, что при появлении симптомов аллергии следует прекратить прием толперизона и немедленно обратиться за медицинской помощью.\u003Cbr\u003EПосле эпизода гиперчувствительности к толперизону повторно назначать препарат нельзя.\u003Cbr\u003EПрепарат Мидокалм к содержит лактозы моногидрат. Пациентам с редкой наследственной непереносимостью галактозы, недостаточностью лактазы и глюкозо-галактозной мальабсорбцией не следует принимать Мидокалм.\u003Cbr\u003E"},{"name":"Взаимодействие","value":"В фармакокинетических исследованиях лекарственных взаимодействий установлено, что совместный прием толперизона с субстратом изофермента CYP2D6 декстраметорфаном способствует увеличению концентрации в крови средств, которые метаболизируются преимущественно изоферментом CYP2D6, например, тиоридазина, толтеродина, венлафаксина, атомоксетина, дезипрамина, декстрометорфана, метопролола, небиволола и\u003Cbr\u003Eперфеназина.\u003Cbr\u003EВ исследованиях in vitro на микросомах печени человека и гепатоцитах человека выраженное ингибирование или индукция других изоферментов (CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP1A2, CYP3A4) не подтверждены.\u003Cbr\u003EПовышение экспозиции толперизона не ожидается после одновременного введения субстратов изофермента CYP2D6 и/или других препаратов из-за разнообразия метаболических путей толперизона.\u003Cbr\u003EБиодоступность толперизона снижается при приеме натощак, поэтому применение препарата рекомендуется после приема пищи.\u003Cbr\u003EХотя толперизон влияет на центральную нервную систему, его потенциальный седативный эффект низкий. В случае совместного приема с другими миорелаксантами центрального действия следует оценить необходимость снижения дозы толперизона.\u003Cbr\u003EТолперизон усиливает действие нифлумовой кислоты, поэтому следует уменьшить дозу нифлумовой кислоты или другого НПВП в случае одновременного применения с толперизоном.\u003Cbr\u003E"},{"name":"Регистрационный номер","value":"P N002409/01"},{"name":"Дата государственной регистрации","value":"02.08.2022"},{"name":"Владелец регистрационного удостоверения","value":"Гедеон Рихтер ОАО"},{"name":"Изготовитель","value":"Гедеон Рихтер-РУС"},{"name":"Страна бренда","value":"Венгрия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Мидокалм"},{"name":"Срок годности","value":"855 дн."}]}],"transitionId":"tr_6"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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диоксид коллоидный; титана диоксид Е 171; лактозы моногидрат; макрогол 6000; гипромеллоза.\u003Cbr\u003E"},{"description":"","filters":[{"id":27144131,"name":"Действующее вещество"}],"isMainProperty":false,"name":"Действующее вещество","value":"Толперизон"},{"description":"","filters":[{"id":15768000,"name":"Способ применения и дозы"}],"isMainProperty":false,"name":"Способ применения и дозы","value":"Внутрь после еды, запивая стаканом воды.\u003Cbr /\u003EБиодоступность толперизона снижается при приеме натощак.\u003Cbr /\u003EДоза препарата подбирается исходя из индивидуальной потребности пациента и переносимости препарата.\u003Cbr /\u003EВзрослые и поДростки старше 14 лет\u003Cbr /\u003EРекомендованная суточная доза в зависимости от индивидуальной потребности и переносимости препарата пациентом составляет 150 — 450 мг, разделенная на З приема.\u003Cbr /\u003EПациенты с почечной недостаточностью\u003Cbr /\u003EОпыт применения толперизона у пациентов с почечной недостаточностью ограничен, у данной категории пациентов чаще возникали нежелательные реакции. Поэтому у пациентов с нарушениями функции почек средней степени необходимо проводить подбор дозы толперизона с тщательным наблюдением за состоянием здоровья пациента и контролем функции почек. При тяжелом поражении почек назначение толперизона не рекомендуется.\u003Cbr /\u003EПациенты с печеночной недостаточностью\u003Cbr /\u003EОпыт применения толперизона у пациентов с печеночной недостаточностью ограничен, у данной категории пациентов чаще возникали нежелательные реакции. Поэтому у пациентов с нарушениями функции печени средней степени необходимо проводить подбор дозы толперизона с тщательным наблюдением за состоянием здоровья пациента и контролем функции печени. При тяжелом поражении печени назначение толперизона не рекомендуется.\u003Cbr /\u003EПрименение у Детей\u003Cbr /\u003EДети от З до 6 лет: препарат назначается внутрь в суточной дозе 5 мг/кг массы тела, распределенной на З приема.\u003Cbr /\u003EДети и подростки от 7 до 14 лет: препарат назначается внутрь в суточной дозе 2 — 4 мг/кг, распределенной на З приема.\u003Cbr /\u003EУчитывая малую величину доз, детям следует назначать препарат в виде таблеток, покрытых пленочной оболочкой, 50 мг."},{"description":"","filters":[{"id":15767998,"name":"Побочные действия"}],"isMainProperty":false,"name":"Побочные действия","value":"Профиль безопасности толперизона оценивался по данным постмаркетингового применения более чем у 12 000 пациентов.\u003Cbr\u003EВ соответствии с этими данными наиболее частыми были нарушения со стороны кожи и подкожных тканей, общие расстройства, нарушения со стороны нервной системы и желудочно-кишечного тракта.\u003Cbr\u003EПри постмаркетинговом применении реакции гиперчувствительности составили 50 - 60% всех побочных реакций. Большинство побочных реакций не были серьезными и проходили самостоятельно. Жизнеугрожающие реакции гиперчувствительности регистрировались очень редко.\u003Cbr\u003EПобочные реакции приведены ниже в соответствии с классификацией MedDRA и частотой: нечасто (от \u003E1/1 000 до \u003C1/100); редко (от \u003E1/10 000 до \u003C1/1 000); очень редко (\u003C1/10 000); частота неизвестна (невозможно оценить на основании имеющихся данных).\u003Cbr\u003EНарушения со стороны крови и лимфатической системы\u003Cbr\u003EОчень редко: анемия, лимфаденопатия.\u003Cbr\u003EНарушения со стороны иммунной системы\u003Cbr\u003EРедко: реакция гиперчувствительности, анафилактическая реакция; Очень редко: анафилактический шок; Частота неизвестна: ангионевротический отек, включая отек лица, губ.\u003Cbr\u003EНарушения со стороны обмена веществ и питания\u003Cbr\u003EНечасто: анорексия; Очень редко: полидипсия.\u003Cbr\u003EНарушения психики\u003Cbr\u003EНечасто: бессонница, нарушения сна; Редко: снижение активности, депрессия; Очень редко: спутанность сознания.\u003Cbr\u003EНарушения со стороны нервной системы\u003Cbr\u003EНечасто: головная боль, головокружение, сонливость; Редко: нарушение внимания, тремор, эпилепсия, гипестезия, парестезия, летаргия.\u003Cbr\u003EНарушения со стороны органа зрения\u003Cbr\u003EРедко: нечеткость зрения.\u003Cbr\u003EНарушения со стороны органа слуха и лабиринтные нарушения\u003Cbr\u003EРедко: шум в ушах, вертиго.\u003Cbr\u003EНарушения со стороны сердца\u003Cbr\u003EРедко: стенокардия, тахикардия, ощущение сердцебиения; Очень редко: брадикардия.\u003Cbr\u003EНарушения со стороны сосудов\u003Cbr\u003EНечасто: артериальная гипотензия; Редко: «приливы».\u003Cbr\u003EНарушения со стороны дыхательной системы, органов грудной клетки и средостения\u003Cbr\u003EРедко: одышка, носовое кровотечение, учащенное дыхание.\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта\u003Cbr\u003EНечасто: дискомфорт в животе, диарея, сухость во рту, диспепсия, тошнота; Редко: боль в эпигастральной области, запор, метеоризм, рвота.\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей\u003Cbr\u003EРедко: печеночная недостаточность легкой степени.\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей\u003Cbr\u003EРедко: аллергический дерматит, повышенная потливость, зуд, крапивница, сыпь.\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей\u003Cbr\u003EРедко: энурез, протеинурия.\u003Cbr\u003EНарушения со стороны скелетно-мышечной и соединительной ткани\u003Cbr\u003EНечасто: мышечная слабость, миалгия, боль в конечностях; Редко: дискомфорт в конечностях; Очень редко: остеопения.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения\u003Cbr\u003EНечасто: астения, дискомфорт, усталость; Редко: чувство опьянения, чувство жара, раздражительность, жажда; Очень редко: дискомфорт в грудной клетке.\u003Cbr\u003EЛабораторные и инструментальные данные\u003Cbr\u003EРедко: снижение артериального давления, гипербилирубинемия, изменение активности печеночных ферментов, тромбоцитопения, лейкоцитоз; Очень редко: увеличение концентрации креатинина в плазме крови.\u003Cbr\u003EЕсли любые из указанных в инструкции нежелательных реакций усугубляются, или Вы заметили любые другие нежелательные реакции, не указанные в инструкции, сообщите об этом лечащему врачу.\u003Cbr\u003E"},{"description":"","filters":[{"id":15768001,"name":"Фармакологическое действие"}],"isMainProperty":false,"name":"Фармакологическое действие","value":"Толперизон является миорелаксантом центрального действия. Точный механизм действия полностью не выяснен. Толперизон обладает высокой аффинностью к нервной ткани, достигая наибольших концентраций в стволе головного мозга, спинном мозге и периферической нервной системе. Основной эффект толперизона опосредован торможением спинальных рефлекторных дуг. Вероятно, этот эффект совместно с устранением облегчения проведения возбуждения по нисходящим путям обеспечивает терапевтическое воздействие толперизона.\u003Cbr\u003EХимическая структура толперизона схожа со структурой лидокаина. Подобно лидокаину, он обладает мембраностабилизирующим действием и снижает электрическую возбудимость двигательных нейронов и первичных афферентных волокон. Толперизон дозозависимо тормозит активность потенциалзависимых натриевых каналов.\u003Cbr\u003EСоответственно, снижается амплитуда и частота потенциала действия.\u003Cbr\u003EБыл доказан угнетающий эффект на потенциалзависимые кальциевые каналы.\u003Cbr\u003EПредполагается, что в дополнение к его мембраностабилизирующему действию толперизон может также тормозить выброс медиатора. Толперизон обладает некоторыми слабыми свойствами альфа-адренергических антагонистов и антимускариновым действием.\u003Cbr\u003E"},{"description":"","filters":[{"id":34045110,"name":"Фармакологическая группа"}],"isMainProperty":false,"name":"Фармакологическая группа","value":"миорелаксант центрального действия"},{"description":"","filters":[{"id":27141511,"name":"Форма выпуска для карточки"}],"isMainProperty":false,"name":"Форма выпуска","value":"таблетки, покрытые пленочной оболочкой"},{"description":"","filters":[{"id":35947170,"name":"Способ применения/введения"}],"isMainProperty":false,"name":"Способ применения/введения","value":"пероральный"},{"description":"","filters":[{"id":23679511,"name":"Минимальный возраст применения"},{"id":16082123,"name":"С рождения"}],"isMainProperty":false,"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","specs":[{"description":"","filters":[{"id":15767999,"name":"Условия хранения"}],"isMainProperty":false,"name":"Условия хранения","value":"При температуре не выше 25°С. Хранить в недоступном для детей месте."},{"description":"","filters":[{"id":15768014,"name":"Передозировка"}],"isMainProperty":false,"name":"Передозировка","value":"Симптомы передозировки чаще всего включают: сонливость, желудочно-кишечные\u003Cbr\u003Eнарушения (тошнота, рвота, боль в эпигастрии), тахикардия, повышение артериального давления, брадикинезия и вертиго. В тяжелых случаях судороги, угнетение дыхания, апноэ\u003Cbr\u003Eи кома.\u003Cbr\u003EЛечение: специфического антидота нет, рекомендована симптоматическая терапия.\u003Cbr\u003E"},{"description":"","filters":[{"id":15768015,"name":"Применение при беременности и кормлении грудью"}],"isMainProperty":false,"name":"Применение при беременности и кормлении грудью","value":"Беременность\u003Cbr\u003EВ экспериментальных исследованиях на животных не выявлено тератогенного действия толперизона. По причине отсутствия значимых клинических данных толперизон не следует применять при беременности, за исключением случаев, когда ожидаемая польза определенно оправдывает потенциальный риск для плода.\u003Cbr\u003EПериод грудного вскармливания Поскольку данные о выделении толперизона с грудным молоком отсутствуют, то его применение в период кормления грудью противопоказано.\u003Cbr\u003E"},{"description":"","filters":[{"id":17360993,"name":"Влияние на способность управлять транспортом и механизмами"}],"isMainProperty":false,"name":"Влияние на способность управлять транспортом и механизмами","value":"Толперизон не оказывает влияния на способность к управлению транспортными средствами и механизмами. Пациентам, у которых есть головокружение, сонливость, нарушение внимания, эпилепсия, нечеткость зрения или мышечная слабость во время приема толперизона, следует проконсультироваться с врачом."},{"description":"","filters":[{"id":15771167,"name":"Особые указания"}],"isMainProperty":false,"name":"Особые указания","value":"С осторожностью\nПрепарат следует применять с осторожностью у женщин, пациентов с гиперчувствительностью к лидокаину и/или другим препаратам или с аллергией в анамнезе (см. раздел «Особые указания»), у пациентов с почечной и печеночной недостаточностью (см. раздел «Способ применения и дозы»).\u003Cbr\u003EЕсли у Вас имеется какое-либо из вышеперечисленных состояний/заболеваний перед приемом препарата обязательно проконсультируйтесь с врачом.\u003Cbr\u003EНаиболее частыми нежелательными реакциями при применении толперизона в пострегистрационном периоде были реакции гиперчувствительности. Их выраженность варьирует от легких кожных реакций до тяжелых системных реакций, включая анафилактический шок. Симптомами реакций гиперчувствительности могут быть эритема, сыпь, крапивница, зуд, ангионевротический отек, тахикардия, артериальная гипотензия или одышка.\u003Cbr\u003EЖенщины и пациенты с повышенной чувствительностью к другим препаратам или с аллергией в анамнезе могут быть подвержены более высокому риску гиперчувствительности к толперизону.\u003Cbr\u003EВ случае известной гиперчувствительности к лидокаину при применении толперизона следует соблюдать повышенную осторожность из-за возможных перекрестных реакций.\u003Cbr\u003EНеобходимо рекомендовать пациентам иметь настороженность в отношении возможных симптомов аллергии. Пациенты должны быть осведомлены о том, что при появлении симптомов аллергии следует прекратить прием толперизона и немедленно обратиться за медицинской помощью.\u003Cbr\u003EПосле эпизода гиперчувствительности к толперизону повторно назначать препарат нельзя.\u003Cbr\u003EПрепарат Мидокалм к содержит лактозы моногидрат. Пациентам с редкой наследственной непереносимостью галактозы, недостаточностью лактазы и глюкозо-галактозной мальабсорбцией не следует принимать Мидокалм.\u003Cbr\u003E"},{"description":"","filters":[{"id":15768012,"name":"Взаимодействие"}],"isMainProperty":false,"name":"Взаимодействие","value":"В фармакокинетических исследованиях лекарственных взаимодействий установлено, что совместный прием толперизона с субстратом изофермента CYP2D6 декстраметорфаном способствует увеличению концентрации в крови средств, которые метаболизируются преимущественно изоферментом CYP2D6, например, тиоридазина, толтеродина, венлафаксина, атомоксетина, дезипрамина, декстрометорфана, метопролола, небиволола и\u003Cbr\u003Eперфеназина.\u003Cbr\u003EВ исследованиях in vitro на микросомах печени человека и гепатоцитах человека выраженное ингибирование или индукция других изоферментов (CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP1A2, CYP3A4) не подтверждены.\u003Cbr\u003EПовышение экспозиции толперизона не ожидается после одновременного введения субстратов изофермента CYP2D6 и/или других препаратов из-за разнообразия метаболических путей толперизона.\u003Cbr\u003EБиодоступность толперизона снижается при приеме натощак, поэтому применение препарата рекомендуется после приема пищи.\u003Cbr\u003EХотя толперизон влияет на центральную нервную систему, его потенциальный седативный эффект низкий. В случае совместного приема с другими миорелаксантами центрального действия следует оценить необходимость снижения дозы толперизона.\u003Cbr\u003EТолперизон усиливает действие нифлумовой кислоты, поэтому следует уменьшить дозу нифлумовой кислоты или другого НПВП в случае одновременного применения с толперизоном.\u003Cbr\u003E"},{"description":"","filters":[{"id":16435314,"name":"Регистрационный номер"}],"isMainProperty":false,"name":"Регистрационный номер","value":"P N002409/01"},{"description":"","filters":[{"id":16435315,"name":"Дата государственной регистрации"}],"isMainProperty":false,"name":"Дата государственной регистрации","value":"02.08.2022"},{"description":"","filters":[{"id":34324371,"name":"Тип препарата"},{"id":7893318,"name":"Производитель"}],"isMainProperty":false,"name":"Владелец регистрационного удостоверения","value":"Гедеон Рихтер ОАО"},{"description":"","filters":[{"id":35771390,"name":"Изготовитель"}],"isMainProperty":false,"name":"Изготовитель","value":"Гедеон 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  • Мидокалм Лонг таб. пролонг. высвоб. п/о плен., 450 мг, 30 шт.
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    Мидокалм Лонг таб. пролонг. высвоб. п/о плен., 450 мг, 30 шт.

    Рейтинг товара: 4.9 из 5
    на основе 7 оценок
    Цена 1 529 ₽
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  • Толперизон Канон таб. п/о плен., 50 мг, 30 шт.
    –22 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-5dw24icgvj/toggleWishlist":{"skuId":"101774414942","productId":1741450876,"offerId":"wfvuAv015ME4Ev27NP9zMA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQxNPxnOzA1elEEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcI/NyxvgYQ3qjpkfsCGM7C2Qcg59zBBw==","sign":"GNxznTP//QbN192XFXJiYqwAm/sw4a8XmUpKd90Gf3A="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-5dw24icgvj/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Толперизон Канон таб. п/о плен., 50 мг, 30 шт.

    Рейтинг товара: 4.7 из 5
    на основе 35 оценок
    Цена 176 ₽ вместо 226
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  • Мидокалм-Рихтер р-р для в/м введ. амп., 100 мг+2.5 мг/мл, 1 мл, 5 шт.
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    Мидокалм-Рихтер р-р для в/м введ. амп., 100 мг+2.5 мг/мл, 1 мл, 5 шт.

    Рейтинг товара: 5 из 5
    на основе 17 оценок
    Цена 683 ₽
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  • Аркоксиа таб. п/о. плен., 120 мг, 7 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-dqr7ev2g2vr/toggleWishlist":{"skuId":"227843632","productId":1422663482,"offerId":"W7b_SbKi7PQbGr81nSrQ6Q","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQxNPxnOzA1elEEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIur6wpgUQsLzSbBiL1NAHIOfcwQc=","sign":"vczfQX8ZqAgykT882H4Cs8lgjMQnpro3Ph7/3GWMFRU="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-dqr7ev2g2vr/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Аркоксиа таб. п/о. плен., 120 мг, 7 шт.

    Рейтинг товара: 4.9 из 5
    на основе 39 оценок
    Цена 816 ₽
    {"widgets":{"@light/AddToCartButtonSnippet":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-dqr7ev2g2vr/addToCartButton":{"offerId":"W7b_SbKi7PQbGr81nSrQ6Q","skuId":"227843632","pendingCartItem":{"productId":1422663482,"offerId":"W7b_SbKi7PQbGr81nSrQ6Q","showPlaceId":"OTNDnItfwRMjN9MRHuEMMoqEA9ZAF5nycOtWOhEhSwghdCsskfwbty9MFtxis9MLNIWVxS9z-cpNA7SIMN3hGO0PpcKdnra6RCO-azg5XbiI5PaGUIF_HnyZksBtG4Ms36qrmCB5-oNWV3p1XFs9tlKweZYNxEBrxINOGq1DG_UV3FEAISOe71JYc9BkKMM7Kp7cs-CktaUBVWdae_eEkQ,,","feeShow":"OTNDnItfwRMjN9MRHuEMMoqEA9ZAF5nycOtWOhEhSwghdCsskfwbty9MFtxis9MLNIWVxS9z-cpNA7SIMN3hGO0PpcKdnra6RCO-azg5XbiI5PaGUIF_HnyZksBtG4Ms36qrmCB5-oNWV3p1XFs9tlKweZYNxEBrxINOGq1DG_UV3FEAISOe71JYc9BkKMM7Kp7cs-CktaUBVWdae_eEkQ,,","skuId":"227843632","shopId":55106433,"price":{"applicablePriceDiscounts":[],"value":"816","currency":"RUR"},"hid":"15756903","name":"Аркоксиа таб. п/о. плен., 120 мг, 7 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  • Сирдалуд таб., 2 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ayjhlv8zlps/toggleWishlist":{"skuId":"228082363","productId":1422663513,"offerId":"E-jDJolizZ_cdSFuEF-eZQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQxNPxnOzA1elEEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI2b6wpgUQu4XhbBiQ1aEFIOfcwQc=","sign":"AJn1c+WotKc0IyA2wnVevEPg6+J4MFJG5FXiZTclCEQ="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ayjhlv8zlps/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Сирдалуд таб., 2 мг, 30 шт.

    Рейтинг товара: 4.9 из 5
    на основе 25 оценок
    Цена 172 ₽
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  • Толперизон таб. п/о плен., 150 мг, 30 шт.
    –11 %
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    Толперизон таб. п/о плен., 150 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 4 оценки
    Цена 329 ₽ вместо 369
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  • Аэртал таб. п/о плен., 100 мг, 20 шт.
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    Аэртал таб. п/о плен., 100 мг, 20 шт.

    Рейтинг товара: 4.2 из 5
    на основе 10 оценок
    Цена 591 ₽
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  • Мелоксикам таб., 15 мг, 20 шт.
    –34 %
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    Мелоксикам таб., 15 мг, 20 шт.

    Рейтинг товара: 4.8 из 5
    на основе 42 оценки
    Цена 95 ₽ вместо 145
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  • Толперизон-СЗ таб. п/о плен., 150 мг, 30 шт.
    –20 %
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    Толперизон-СЗ таб. п/о плен., 150 мг, 30 шт.

    Рейтинг товара: 4.7 из 5
    на основе 13 оценок
    Цена 201 ₽ вместо 251
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  • Нимесулид таб., 100 мг, 10 шт.
    –42 %
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    Нимесулид таб., 100 мг, 10 шт.

    Рейтинг товара: 4.9 из 5
    на основе 108 оценок
    Цена 70 ₽ вместо 120
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Инструкция

Показания к применению

Симптоматическое лечение спастичности у взрослых, обусловленной инсультом.
Миофасциальный болевой синдром средней и тяжелой степени (в том числе мышечный спазм при дорсопатиях).

Противопоказания

- гиперчувствительность к любому из компонентов препарата или химически сходному
Эперизону;
- миастения gravis;
- беременность и период грудного вскармливания;
- детский возраст до 18 лет;
- непереносимость галактозы, лактазная недостаточность, глюкозо-галактозная мальабсорбция.

Способ применения и дозы

Внутрь после еды, запивая стаканом воды.
Биодоступность толперизона снижается при приеме натощак.
Доза препарата подбирается исходя из индивидуальной потребности пациента и переносимости препарата.
Взрослые и поДростки старше 14 лет
Рекомендованная суточная доза в зависимости от индивидуальной потребности и переносимости препарата пациентом составляет 150 — 450 мг, разделенная на З приема.
Пациенты с почечной недостаточностью
Опыт применения толперизона у пациентов с почечной недостаточностью ограничен, у данной категории пациентов чаще возникали нежелательные реакции. Поэтому у пациентов с нарушениями функции почек средней степени необходимо проводить подбор дозы толперизона с тщательным наблюдением за состоянием здоровья пациента и контролем функции почек. При тяжелом поражении почек назначение толперизона не рекомендуется.
Пациенты с печеночной недостаточностью
Опыт применения толперизона у пациентов с печеночной недостаточностью ограничен, у данной категории пациентов чаще возникали нежелательные реакции. Поэтому у пациентов с нарушениями функции печени средней степени необходимо проводить подбор дозы толперизона с тщательным наблюдением за состоянием здоровья пациента и контролем функции печени. При тяжелом поражении печени назначение толперизона не рекомендуется.
Применение у Детей
Дети от З до 6 лет: препарат назначается внутрь в суточной дозе 5 мг/кг массы тела, распределенной на З приема.
Дети и подростки от 7 до 14 лет: препарат назначается внутрь в суточной дозе 2 — 4 мг/кг, распределенной на З приема.
Учитывая малую величину доз, детям следует назначать препарат в виде таблеток, покрытых пленочной оболочкой, 50 мг.
Полная инструкция
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Мидокалм таб. п/о плен.
Мидокалм таб. п/о плен., 50 мг, 30 шт.
4.9
(40)
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6 вопросов
Инструкция

550 ₽

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4.9
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У продавца:40 оценок·2 отзыва
У всех продавцов:300 оценок·89 отзывов
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user avatar
2 месяца назад • Светлана Блинова • Куплен на Маркете
Достоинства: нормальные таблетки, как в аптеке
Недостатки: нет
Комментарий: принимаю не один год
user avatar
3 месяца назад • Татьяна Красильцева • Куплен на Маркете
Достоинства: это медикамент
Посмотреть все отзывы на Маркете
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    Цена 204 ₽ вместо 254
  • Версатис пластырь, 5 шт.
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    Версатис пластырь, 5 шт.

    Цена 988 ₽
  • Нейробион таб. п/о, 20 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:186870040_6/content/content/gallery":{"title":"Нейробион таб. п/о, 20 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/4304169/img_id2785167164665643563.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4304169/img_id2785167164665643563.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4304169/img_id2785167164665643563.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4304169/img_id2785167164665643563.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4304169/img_id2785167164665643563.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4304169/img_id2785167164665643563.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 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    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:186870040_6/content/content/toggleWishlist":{"skuId":"101305934730","productId":186870040,"offerId":"olnbB8fsiyfS_rSKumHx7g","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQxNPxnOzA1elEEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCJjSjVkQise3svkCGLiOoQYgnP6jGA==","sign":"z0S8dLp7O2d9LjYkNjBzZivjlPr8K41c3fE6J7HsXBM="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:186870040_6/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Нейробион таб. п/о, 20 шт.

    Цена 501 ₽ вместо 635
  • Мексидол таб. п/о плен., 125 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1404748441_7/content/content/gallery":{"title":"Мексидол таб. п/о плен., 125 мг, 30 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/5251231/img_id7904680617177569775.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5251231/img_id7904680617177569775.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5251231/img_id7904680617177569775.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5251231/img_id7904680617177569775.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5251231/img_id7904680617177569775.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5251231/img_id7904680617177569775.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/5236248/img_id7022193557611552722.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5236248/img_id7022193557611552722.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5236248/img_id7022193557611552722.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5236248/img_id7022193557611552722.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5236248/img_id7022193557611552722.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5236248/img_id7022193557611552722.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/1733932/img_id4016919253603601542.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/1733932/img_id4016919253603601542.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/1733932/img_id4016919253603601542.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/1733932/img_id4016919253603601542.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/1733932/img_id4016919253603601542.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/1733932/img_id4016919253603601542.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/7552302/img_id7252453480823567390.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/7552302/img_id7252453480823567390.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/7552302/img_id7252453480823567390.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/7552302/img_id7252453480823567390.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/7552302/img_id7252453480823567390.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/7552302/img_id7252453480823567390.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/1081556/img_id8851580815583959802.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/1081556/img_id8851580815583959802.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/1081556/img_id8851580815583959802.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/1081556/img_id8851580815583959802.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/1081556/img_id8851580815583959802.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/1081556/img_id8851580815583959802.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQxNPxnOzA1elEEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIVCJmF650FEI7X0GwYre38BSDt2cEH","sign":"PIxUSyz6MOxd9P8MEIOHWATnpVtba02DP1aQc/ZhdI8="},"target":"model_card"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1404748441_7/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1404748441_7/content/content/toggleWishlist":{"skuId":"227814286","productId":1404748441,"offerId":"Gowj-_88fqDv5M_iD0Gd2w","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQxNPxnOzA1elEEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIVCJmF650FEI7X0GwYre38BSDt2cEH","sign":"PIxUSyz6MOxd9P8MEIOHWATnpVtba02DP1aQc/ZhdI8="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1404748441_7/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Мексидол таб. п/о плен., 125 мг, 30 шт.

    Цена 272 ₽ вместо 322
  • Реклама
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  • Мидокалм-Рихтер р-р для в/м введ. амп., 100 мг+2.5 мг/мл, 1 мл, 5 шт.
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    Мидокалм-Рихтер р-р для в/м введ. амп., 100 мг+2.5 мг/мл, 1 мл, 5 шт.

    Цена 683 ₽
  • Аркоксиа таб. п/о. плен., 120 мг, 7 шт.
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    Аркоксиа таб. п/о. плен., 120 мг, 7 шт.

    Цена 816 ₽
  • Комбилипен табс таб. п/о плен., 30 шт.
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    Комбилипен табс таб. п/о плен., 30 шт.

    Цена 445 ₽
  • Мексидол форте таб. п/о. плен., 250 мг, 40 шт.
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    Мексидол форте таб. п/о. плен., 250 мг, 40 шт.

    Цена 774 ₽ вместо 979
  • Кокарнит лиоф. д/приг. р-ра для в/м введ. + р-ль лидокаина р-р амп., 3 шт.
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    Кокарнит лиоф. д/приг. р-ра для в/м введ. + р-ль лидокаина р-р амп., 3 шт.

    Цена 1 043 ₽
  • Мильгамма р-р для в/м введ., 5 шт.
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217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4343092/img_id8015786398950236198.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4343092/img_id8015786398950236198.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4343092/img_id8015786398950236198.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4343092/img_id8015786398950236198.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4343092/img_id8015786398950236198.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4343092/img_id8015786398950236198.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/7666641/img_id710380372123103137.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/7666641/img_id710380372123103137.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/7666641/img_id710380372123103137.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/7666641/img_id710380372123103137.jpeg/240x320 240w, 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217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQxNPxnOzA1elEEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCJWTrVkQxqfws/kCGLqCoQYgnP6jGA==","sign":"N6MAb+qjCeDMPATPYrKy2TetxSby8Pk1yzixHgg6igk="},"target":"model_card"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:187386261_14/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:187386261_14/content/content/toggleWishlist":{"skuId":"101308961734","productId":187386261,"offerId":"0_RAaayhB3PuXy7ke19xbw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQxNPxnOzA1elEEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCJWTrVkQxqfws/kCGLqCoQYgnP6jGA==","sign":"N6MAb+qjCeDMPATPYrKy2TetxSby8Pk1yzixHgg6igk="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:187386261_14/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Мильгамма р-р для в/м введ., 5 шт.

    Цена 501 ₽ вместо 591
  • Сирдалуд таб., 2 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1422663513_15/content/content/toggleWishlist":{"skuId":"228082363","productId":1422663513,"offerId":"E-jDJolizZ_cdSFuEF-eZQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQxNPxnOzA1elEEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIVCNm+sKYFELuF4WwYkNWhBSDn3MEH","sign":"0zLrL9tWh+6eF8mYkBwAum3d6P+ORkdfVD4IXfuA4fA="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1422663513_15/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Сирдалуд таб., 2 мг, 30 шт.

    Цена 172 ₽
  • Грандаксин таб., 50 мг, 20 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1404748508_16/content/content/gallery":{"title":"Грандаксин таб., 50 мг, 20 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/6240175/img_id2529195619291355629.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/6240175/img_id2529195619291355629.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/6240175/img_id2529195619291355629.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/6240175/img_id2529195619291355629.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/6240175/img_id2529195619291355629.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/6240175/img_id2529195619291355629.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/7660527/img_id3681844341210763495.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/7660527/img_id3681844341210763495.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/7660527/img_id3681844341210763495.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/7660527/img_id3681844341210763495.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/7660527/img_id3681844341210763495.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/7660527/img_id3681844341210763495.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4489193/img_id8278876893336606955.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4489193/img_id8278876893336606955.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4489193/img_id8278876893336606955.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4489193/img_id8278876893336606955.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4489193/img_id8278876893336606955.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4489193/img_id8278876893336606955.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/5387588/img_id979796346112668131.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5387588/img_id979796346112668131.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5387588/img_id979796346112668131.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5387588/img_id979796346112668131.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5387588/img_id979796346112668131.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5387588/img_id979796346112668131.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQxNPxnOzA1elEEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIVCNyF650FEK7J0GwYkt3QByDt2cEH","sign":"nRLAOB3pw9WetmIqhdxsIvRhukLIl6Xgs0nSMJETH+8="},"target":"model_card"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1404748508_16/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1404748508_16/content/content/toggleWishlist":{"skuId":"227812526","productId":1404748508,"offerId":"agNbUZJ46QY771mBK2vCMQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQxNPxnOzA1elEEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIVCNyF650FEK7J0GwYkt3QByDt2cEH","sign":"nRLAOB3pw9WetmIqhdxsIvRhukLIl6Xgs0nSMJETH+8="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1404748508_16/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Грандаксин таб., 50 мг, 20 шт.

    Цена 552 ₽
  • Толперизон таб. п/о плен., 150 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1422663515_17/content/content/gallery":{"title":"Толперизон таб. п/о плен., 150 мг, 30 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/5229821/img_id1746455809152381515.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5229821/img_id1746455809152381515.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5229821/img_id1746455809152381515.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5229821/img_id1746455809152381515.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5229821/img_id1746455809152381515.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5229821/img_id1746455809152381515.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/1514097/img_id3490654576424654994.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/1514097/img_id3490654576424654994.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/1514097/img_id3490654576424654994.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/1514097/img_id3490654576424654994.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/1514097/img_id3490654576424654994.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/1514097/img_id3490654576424654994.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQxNPxnOzA1elEEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIVCNu+sKYFELPG4WwYhKmyCCDn3MEH","sign":"oJiSlbV/ugO6TFC5bJZ8+oT8IEsFRY/RX+I3CyXaZbY="},"target":"model_card"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1422663515_17/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1422663515_17/content/content/toggleWishlist":{"skuId":"228090675","productId":1422663515,"offerId":"jmdFxZhS2HV_Del7vXIY-g","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQxNPxnOzA1elEEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIVCNu+sKYFELPG4WwYhKmyCCDn3MEH","sign":"oJiSlbV/ugO6TFC5bJZ8+oT8IEsFRY/RX+I3CyXaZbY="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1422663515_17/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Толперизон таб. п/о плен., 150 мг, 30 шт.

    Цена 329 ₽ вместо 369
  • Ларигама р-р для в/м введ. амп., 5 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:649336188_18/content/content/gallery":{"title":"Ларигама р-р для в/м введ. амп., 5 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/1883514/img_id6568343226391114593.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/1883514/img_id6568343226391114593.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/1883514/img_id6568343226391114593.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/1883514/img_id6568343226391114593.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/1883514/img_id6568343226391114593.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/1883514/img_id6568343226391114593.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4408567/img_id620726715580593928.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4408567/img_id620726715580593928.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4408567/img_id620726715580593928.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4408567/img_id620726715580593928.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4408567/img_id620726715580593928.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4408567/img_id620726715580593928.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/1644362/img_id6809745372794178378.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/1644362/img_id6809745372794178378.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/1644362/img_id6809745372794178378.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/1644362/img_id6809745372794178378.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/1644362/img_id6809745372794178378.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/1644362/img_id6809745372794178378.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4466970/img_id9175482272918497373.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4466970/img_id9175482272918497373.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4466970/img_id9175482272918497373.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4466970/img_id9175482272918497373.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4466970/img_id9175482272918497373.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4466970/img_id9175482272918497373.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/1554397/img_id7925801506187799694.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/1554397/img_id7925801506187799694.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/1554397/img_id7925801506187799694.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/1554397/img_id7925801506187799694.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/1554397/img_id7925801506187799694.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/1554397/img_id7925801506187799694.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQxNPxnOzA1elEEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIXCPyq0LUCEPX0o7H5AhiH3tAHIJz+oxg=","sign":"V0biLqStQkDDRhdNenCRPopVzDeuaxIFV8ZofvvGHLo="},"target":"model_card"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:649336188_18/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:649336188_18/content/content/toggleWishlist":{"skuId":"101303515765","productId":649336188,"offerId":"gvaCodlQxWZmTBB_Dc_YBA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQxNPxnOzA1elEEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIXCPyq0LUCEPX0o7H5AhiH3tAHIJz+oxg=","sign":"V0biLqStQkDDRhdNenCRPopVzDeuaxIFV8ZofvvGHLo="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:649336188_18/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Ларигама р-р для в/м введ. амп., 5 шт.

    Цена 259 ₽
  • Комбилипен р-р д/ин., 5 шт.
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    Комбилипен р-р д/ин., 5 шт.

    Цена 326 ₽
  • Аэртал таб. п/о плен., 100 мг, 20 шт.
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    Аэртал таб. п/о плен., 100 мг, 20 шт.

    Цена 591 ₽
  • Реклама
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  • Мелоксикам таб., 15 мг, 20 шт.
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    Мелоксикам таб., 15 мг, 20 шт.

    Цена 95 ₽ вместо 145
  • Толперизон-СЗ таб. п/о плен., 150 мг, 30 шт.
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    Толперизон-СЗ таб. п/о плен., 150 мг, 30 шт.

    Цена 201 ₽ вместо 251
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