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Описание

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Монтлезир таб. п/о плен., 30 шт.

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5.0
(11)
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Количество штук в упаковке, шт.: 30

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Коротко о товаре

Артикул Маркета
4453171303
Тип препарата
Назначение
Действующее вещество
Возраст
от 15 лет
Инструкция
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аллергия","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-astmy","categoryId":"15756897","navnodeId":"72498","glfilters":["36476390:36618937,36618607"]}}},{"name":"Показания к применению","value":"Лечение симптомов круглогодичного (персистирующего) и сезонного (интермиттирующего) аллергических ринитов."},{"name":"Противопоказания","value":"Повышенная чувствительность к монтелукасту, левоцетиризину (в том числе к производным пиперазина), а также к другим компонентам препарата;\u003Cbr\u003EДефицит лактазы, непереносимость лактозы, глюкозо-галактозная мальабсорбция;\u003Cbr\u003EТерминальная стадия почечной недостаточности (клиренс креатинина ниже 10 мл/мин);\u003Cbr\u003EДетский возраст до 15 лет (ввиду ограниченности данных по безопасности и эффективности);\u003Cbr\u003EБеременность и период грудного вскармливания."},{"name":"Состав","value":"На одну таблетку:\u003Cbr\u003EЯдро\u003Cbr\u003E1 слой:\u003Cbr\u003EДействующее вещество: левоцетиризина дигидрохлорид 5,0 мг;\u003Cbr\u003EВспомогательные вещества: лактозы моногидрат (Таблеттоза 100) 63,5 мг, целлюлоза микрокристаллическая (Avicel PH 102) 30,2 мг, кремния диоксид коллоидный 0,3 мг, магния стеарат 1,0 мг;\u003Cbr\u003E2 слой:\u003Cbr\u003EДействующее вещество: монтелукаст натрия 10,4 мг, эквивалентный монтелукасту 10,0 мг;\u003Cbr\u003EВспомогательные вещества: лактозы моногидрат (Фарматоза 200М) 89,3 мг, целлюлоза микрокристаллическая (Avicel PH 101) 83,2 мг, краситель железа оксид желтый (железа оксид желтый) 0,1мг, кроскармеллоза натрия 13,0 мг, гипролоза (гидроксипропилцеллюлоза) 3,0 мг, магния стеарат 1,0 мг;\u003Cbr\u003EПленочная оболочка\u003Cbr\u003EОпадрай желтый (Опадрай желтый 13В52204) 6,0 мг (гипромеллоза 6сР (НРМС2910) 3,75 мг, титана диоксид 1,4556 мг, макрогол-400 0,375 мг, краситель железа оксид желтый (железа оксид желтый) 0,357 мг, полисорбат-80 0,060 мг, краситель железа оксид красный (железа оксид красный) 0,0024 мг)."},{"name":"Действующее вещество","value":"Левоцетиризин+Монтелукаст","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-astmy","categoryId":"15756897","navnodeId":"72498","glfilters":["27144131:36089469"]}}},{"name":"Способ применения и дозы","value":"Внутрь, запивая водой, независимо от приема пищи.\u003Cbr\u003EВзрослым и детям старше 15 лет: принимать по 1 таблетке 1 раз в сутки.\u003Cbr\u003EПациентам с печеночной недостаточностью коррекции дозы не требуется.\u003Cbr\u003EПациентам с хронической почечной недостаточностью и пациентам пожилого возраста следует корректировать дозу в зависимости от степени почечной недостаточности.\u003Cbr\u003EПациентам с легким нарушением функции почек (клиренс креатинина 50-79 мл/мин) коррекции дозы не требуется.\u003Cbr\u003EУ пациентов с умеренной почечной недостаточностью (клиренс креатинина от 30 до 49 мл/мин) рекомендуемая доза левоцетиризина 5 мг (1 таблетка) через день.\u003Cbr\u003EУ пациентов с тяжелой почечной недостаточностью (клиренс креатинина менее 30 мл/мин) рекомендуемая доза левоцетиризина 5 мг (1 таблетка) 1 раз в 3 дня.\u003Cbr\u003EПродолжительность приема препарата\u003Cbr\u003EПри лечении сезонного (интермиттирующего) ринита (наличие симптомов менее 4 дней в неделю или их общая продолжительность менее 4-х недель) продолжительность лечения зависит от длительности симптоматики; лечение может быть прекращено при исчезновении симптомов и возобновлено при появлении симптомов.\u003Cbr\u003EПри лечении круглогодичного (персистирующего) аллергического ринита (наличие симптомов более 4-х дней в неделю и их общая продолжительность более 4-х недель) лечение может продолжаться в течение всего периода воздействия аллергенов.\u003Cbr\u003EПри пропуске одного приема препарата не следует принимать дополнительную дозу препарата для компенсации пропущенного приема, рекомендуется принять следующую дозу в обычное время."},{"name":"Побочные действия","value":"Перечисленные ниже нежелательные явления распределены по частоте возникновения в соответствии со следующей градацией: очень часто (≥ 1/10), часто (от ≥ 1/100 до \u003C 1/10), нечасто (от≥ 1/1000 до \u003C 1/100), редко (от≥ 1/10000 до \u003C 1/1000), очень редко (\u003C 1/10000), частота неизвестна (частота не может быть подсчитана по имеющимся данным).\u003Cbr\u003EМонтелукаст\u003Cbr\u003EНарушения со стороны крови и лимфатической системы: частота неизвестна - повышенная склонность к кровотечениям, тромбоцитопения.\u003Cbr\u003EНарушения со стороны иммунной системы: редко - реакция гиперчувствительности, в том числе анафилаксия, очень редко - эозинофильная инфильтрация печени.\u003Cbr\u003EНарyшения психики: частота неизвестна - ажитация, в том числе агрессивное поведение или враждебность, тревожность, депрессия, дезориентация, патологические сновидения, галлюцинации, бессонница, раздражительность, беспокойство, сомнамбулизм, суицидальные мысли и поведение (суицидальность), тремор, нарушения внимания и памяти.\u003Cbr\u003EНарушения со стороны нервной системы: редко - головная боль, головокружение, сонливость; очень редко - судороги; частота неизвестна - парестезия/гипестезия.\u003Cbr\u003EНарушения со стороны сердца: частота неизвестна - учащенное сердцебиение.\u003Cbr\u003EНарушения со стороны дыхательной системы, органов грудной клетки и средостения: редко - носовое кровотечение, частота неизвестна - инфекции верхних дыхательных путей, фарингит, кашель, синусит, ринорея, синдром Чарджа-Стросса.\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта: редко - изжога, отрыжка, боль в животе; частота неизвестна- диарея, рвота, диспепсия, тошнота, запоры, панкреатит, сухость во рту.\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей: редко - повышение активности \"печеночных\" трансаминаз в сыворотке крови (аланинаминотрансфераза (АЛТ), аспартатаминотрансфераза (ACT)), очень редко - гепатит (включая холестатические, гепатоцеллюлярные и смешанные поражения печени).\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей: редко - кожная сыпь, крапивница; частота неизвестна - ангионевротический отек, появление экхимозов, узловатая эритема, многоформная эритема, кожный зуд.\u003Cbr\u003EНарушения со стороны скелетно-мышечной и соединительной ткани: редко - артралгия; частота неизвестна - миалгия, включая спазмы мышц.\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей: частота неизвестна - энурез у детей.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения: редко - астения (слабость)/усталость; частота неизвестна - отеки, пирексия, жажда.\u003Cbr\u003EЛевоцетиризин\u003Cbr\u003EНарушения со стороны иммунной системы: частота неизвестна - реакции гиперчувствительности, в том числе анафилактические реакции.\u003Cbr\u003EНарушения со стороны обмена веществ и питания: частота неизвестна - повышение аппетита, повышение массы тела.\u003Cbr\u003EНарушения психики: часто - головная боль, сонливость, утомляемость; нечасто - астения; частота неизвестна- тревога, агрессия, возбуждение, бессонница, галлюцинации, депрессия, суицидальные мысли.\u003Cbr\u003EНарушения со стороны нервной системы: частота неизвестна - судороги, тромбоз синусов твердой мозговой оболочки, парестезия, головокружение, обморок, тремор, дисгевзия (нарушение вкуса).\u003Cbr\u003EНарушения со стороны органа зрения: частота неизвестна - нарушение зрения, диплопия, воспаление, нечеткость зрительного восприятия.\u003Cbr\u003EНарушения со стороны органа слуха и лабиринтные нарушения: частота неизвестна - вертиго.\u003Cbr\u003EНарушения со стороны сердца: частота неизвестна - тахикардия, стенокардия, ощущение сердцебиения.\u003Cbr\u003EНарушения со стороны сосудов: частота неизвестна - тромбоз яремной вены.\u003Cbr\u003EНарушения со стороны дыхательной системы, органов грудной клетки и средостения: частота неизвестна - диспноэ, усиление симптомов ринита.\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта: часто - сухость во рту; нечасто - боль в животе; частота неизвестна - тошнота, диарея, рвота.\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей: частота неизвестна - гепатит.\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей: частота неизвестна - ангионевротический отек, стойкая лекарственная эритема, сыпь, зуд, крапивница, гипотрихоз, трещины, фотосенсибилизация.\u003Cbr\u003EНарушения со стороны скелетно-мышечной и соединительной ткани: частота неизвестна - боли в мышцах, артралгия.\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей: частота неизвестна - дизурия, задержка мочи, позывы на мочеиспускание.\u003Cbr\u003EЛабораторные и инструментальные данные: частота неизвестна - изменение функциональных проб печени.\u003Cbr\u003EПрочее: частота неизвестна - перекрестная реактивность, периферические отеки.\u003Cbr\u003EЕсли любые из указанных в инструкции побочных эффектов усугубляются, или Вы заметили любые другие побочные эффекты, не указанные в инструкции, сообщите об этом врачу."},{"name":"Фармакологическое действие","value":"Препарат представляет собой комбинацию монтелукаста (лейкотриеновых рецепторов блокатор) и левоцетиризина (Н1-гистаминовых рецепторов блокатор).\u003Cbr\u003EМонтелукаст селективно ингибирует CysLT-рецепторы цистеиниловых лейкотриенов эпителия дыхательных путей. Цистеинил лейкотриеновые рецепторы 1 типа (CysLT-рецепторы) присутствуют в дыхательных путях человека, в том числе в клетках гладких мышц бронхов, макрофагах и других провоспалительных клетках (включая эозинофилы и некоторые миеловидные стволовые клетки). Цистеинил лейкотриены (LTC4, LTD4, LTE4) относятся к классу эйкозаноидов, образующихся из арахидоновой кислоты, и являются медиаторами воспаления, образующимися в различных клетках организма, в том числе в тучных клетках и эозинофилах.\u003Cbr\u003EЦистеинил лейкотриены коррелируют с патофизиологией бронхиальной астмы и аллергического ринита.\u003Cbr\u003EПри аллергическом рините после воздействия аллергена происходит высвобождение цистеинил лейкотриенов из противовоспалительных клеток слизистой оболочки полости носа во время ранней и поздней фаз аллергической реакции, что проявляется симптомами аллергического ринита. При интраназальной пробе с цистеинил лейкотриенами было продемонстрировано повышение симптомов назальной обструкции. Монтелукаст с высоким сродством и избирательностью связывается с CysLT1-рецепторами, снижает число эозинофилов в периферической крови, в дыхательных путях.\u003Cbr\u003EЛевоцетиризин - R-энантиомер цетиризина; конкурентный антагонист гистамина; блокирует Н1-гистаминовые рецепторы, сродство к которым в 2 раза выше, чем у цетиризина. Левоцетиризин оказывает влияние на гистаминозависимую стадию аллергических реакций; уменьшает миграцию эозинофилов, уменьшает сосудистую проницаемость, ограничивает высвобождение медиаторов воспаления и цитокинов (VCAM-1 и других).\u003Cbr\u003EЛевоцетиризин предупреждает развитие и облегчает течение аллергических реакций, оказывает антиэкссудативное, противозудное действие; практически не оказывает антихолинергического и антисеротонинового действия. В терапевтических дозах практически не оказывает седативного действия.\u003Cbr\u003EДействие начинается через 12 минут после приема однократной дозы у 50% пациентов, через 1 час - у 95% и продолжается в течение 24 часов."},{"name":"Фармакологическая группа","value":"Лейкотриеновых рецепторов блокатор+Н1-гистаминовых рецепторов блокатор"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-astmy","categoryId":"15756897","navnodeId":"72498","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 15 лет"},{"name":"Условия хранения","value":"Хранить в защищенном от света месте, при температуре не выше 25 °С.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"Данных о передозировке препаратом не поступало. Однако имеются данные о передозировке отдельными компонентами препарата.\u003Cbr\u003EМонтелукаст\u003Cbr\u003EСимптомы: Наиболее частыми нежелательными явлениями были чувство жажды, сонливость, рвота, психомоторное возбуждение, головная боль и боль в животе.\u003Cbr\u003EЛечение: лечение симптоматическое. Отсутствует информация о специфическом лечении передозировки монтелукастом. Данных о возможности выведения монтелукаста путем перитонеального диализа и гемодиализа нет.\u003Cbr\u003EЛевоцетиризин\u003Cbr\u003EСимптомы: сонливость (у взрослых), возбуждение и беспокойство, сменяющиеся сонливостью (у детей).\u003Cbr\u003EЛечение: промывание желудка, прием активированного угля, симптоматическая терапия. Специфического антидота нет. Гемодиализ неэффективен."},{"name":"Применение при беременности и кормлении грудью","value":"Адекватных и строго контролируемых клинических исследований по безопасности применения препарата во время беременности не проводилось.\u003Cbr\u003EПрименение препарата при беременности противопоказано.\u003Cbr\u003EДанных о выделении монтелукаста с грудным молоком у человека нет.\u003Cbr\u003EЛевоцетиризин выделяется с грудным молоком. Поэтому при необходимости применения препарата при лактации рекомендуется прекратить грудное вскармливание."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Исследований воздействия препарата на способность управлять транспортными средствами и механизмами не проводилось. В период лечения необходимо соблюдать осторожность при вождении автотранспорта и занятии другими потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций, так как препарат может вызывать слабость, сонливость и головокружение."},{"name":"Особые указания","value":"Монтелукаст\u003Cbr\u003EВ редких случаях у пациентов, принимающих препараты для лечения бронхиальной астмы, включая монтелукаст, может возникнуть системная эозинофилия, иногда сопровождающаяся клиническими проявлениями васкулита и синдрома Чарджа-Стросса. Такое состояние обычно лечат системными глюкокортикостероидами. Такие случаи обычно, но не всегда, связаны с уменьшением дозы или отменой пероральных глюкокортикостероидов. Врачи должны знать о возможности возникновения у пациентов эозинофилии, васкулитной сыпи, нарастания легочных симптомов, осложнений со стороны сердца и/или нейропатии.\u003Cbr\u003EПациенты с подтвержденной аллергией к ацетилсалициловой кислоте и другим нестероидным противовоспалительным препаратам (НПВП) не должны принимать эти препараты в период лечения монтелукастом, поскольку он, улучшая дыхательную функцию у пациентов с аллергической бронхиальной астмой, тем не менее, не может полностью предотвратить бронхоконстрикцию, вызванную НПВП.\u003Cbr\u003EУ пациентов, принимавших монтелукаст, были описаны психоневрологические нарушения. Учитывая, что эти симптомы могли быть вызваны другими факторами, неизвестно, связаны ли они с приемом монтелукаста. Врачу необходимо обсудить данные нежелательные явления с пациентами и/или их родителями/опекунами. Пациентам и/или их родителям/опекунам необходимо объяснить, что в случае появления подобных симптомов необходимо сообщить об этом лечащему врачу.\u003Cbr\u003EЛевоцетиризин\u003Cbr\u003EВо время лечения препаратом не рекомендуется принимать этанол."},{"name":"Взаимодействие","value":"Монтелукаст\u003Cbr\u003EМонтелукаст можно назначать вместе с другими лекарственными средствами, традиционно применяемыми для профилактики и длительного лечения бронхиальной астмы и/или аллергического ринита. Рекомендуемая терапевтическая доза монтелукаста не оказывает клинически значимого влияния на фармакокинетику следующих препаратов: теофиллина. преднизона, преднизолона, пероральных контрацептивов (этинилэстрадиол/норэтистерон 35/1), терфенадина, дигоксина и варфарина.\u003Cbr\u003EЗначение AUC снижается при одновременном приеме фенобарбитала (примерно на 40%), однако коррекция режима дозирования монтелукаста не требуется. Поскольку монтелукаст метаболизируется изоферментом CYP 3А4 следует соблюдать осторожность, если монтелукаст одновременно назначается с препаратами, индуцирующими изофермент CYP 3А4, такими как фенитоин, фенобарбитал и рифампицин. Однако изменения дозы монтелукаста не требуется.\u003Cbr\u003EИсследования in vitro показали, что монтелукаст является потенциальным ингибитором изофермента CYP 2С8, однако данные клинических исследований взаимодействия препарат- препарат, включающих монтелукаст и росиглитазон (предварительный субстрат представителя медицинских препаратов, первично метаболизирующихся изоферментом CYP 2С8) показали, что дозы монтелукаста не ингибируют изоферменты CYP 2С8 in vivo. Следовательно, монтелукаст не оказывает заметного влияния на метаболизм препаратов, метаболизирующихся этим ферментом (например, паклитаксел, росиглитазон и репаглинид).\u003Cbr\u003EГемфиброзил (ингибитор CYP 2С8 и 2С9) повышает эффект системного воздействия монтелукаста в 4,4 раза. Однако влияние гемфиброзила на системное воздействие монтелукаста не может считаться клинически значимым на основании данных по безопасности при применении монтелукаста в дозах, превышающих одобренную дозу 10 мг. Поэтому при совместном приеме вместе с гемфиброзилом коррекция дозы монтелукаста не требуется.\u003Cbr\u003EСовместный прием итраконазола, мощного ингибитора CYP 3А4, вместе с гемфиброзилом и монтелукастом не приводил к дополнительному повышению эффекта системного воздействия монтелукаста.\u003Cbr\u003EЛевоцетиризин\u003Cbr\u003EПри изучении лекарственного взаимодействия рацемата цетиризина с феназоном, псевдоэфедрином, циметидином, кетоконазолом, эритромицином, азитромицином, глипизидом и диазепамом клинически значимых нежелательных взаимодействий не выявлено.\u003Cbr\u003EТеофиллин (400 мг/сутки) снижает общий клиренс левоцетиризина на 16%, при этом кинетика теофиллина не изменяется.\u003Cbr\u003EВ исследовании при одновременном приеме ритонавира (600 мг 2 раза в сутки) и цетиризина (10 мг в сутки) показано, что экспозиция цетиризина увеличивалась на 40%, а экспозиция ритонавира незначительно изменялась (-11%).\u003Cbr\u003EСовместное применение с макролидами или кетоконазолом не вызывало достоверных изменений на ЭКГ.\u003Cbr\u003EВ ряде случаев при одновременном применении левоцетиризина с алкоголем или лекарственными препаратами, оказывающими подавляющее влияние на центральную нервную систему (ЦНС), возможно усиление их влияния на ЦНС, хотя не доказано, что рацемат цетиризина потенцирует эффект алкоголя."},{"name":"Регистрационный номер","value":"ЛП-005772"},{"name":"Дата государственной регистрации","value":"04.09.2019"},{"name":"Владелец регистрационного удостоверения","value":"Glenmark","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-astmy","categoryId":"15756897","navnodeId":"72498","glfilters":["34324371:35649313","7893318:16002685"]}}},{"name":"Изготовитель","value":"Glenmark Pharmaceuticals Ltd."},{"name":"Фасовщик","value":"Glenmark"},{"name":"Страна бренда","value":"Индия"},{"name":"Страна-производитель","value":"Индия"},{"name":"Название препарата","value":"Монтлезир","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-astmy","categoryId":"15756897","navnodeId":"72498","glfilters":["17796364:19612037"]}}},{"name":"Срок годности","value":"23 мес."}]}},"fullSpecsGrouped":{"3919616063938397847":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"носовая полость"},{"name":"Назначение","value":"аллергический ринит, сезонная аллергия"},{"name":"Показания к применению","value":"Лечение симптомов круглогодичного (персистирующего) и сезонного (интермиттирующего) аллергических ринитов."},{"name":"Противопоказания","value":"Повышенная чувствительность к монтелукасту, левоцетиризину (в том числе к производным пиперазина), а также к другим компонентам препарата;\u003Cbr\u003EДефицит лактазы, непереносимость лактозы, глюкозо-галактозная мальабсорбция;\u003Cbr\u003EТерминальная стадия почечной недостаточности (клиренс креатинина ниже 10 мл/мин);\u003Cbr\u003EДетский возраст до 15 лет (ввиду ограниченности данных по безопасности и эффективности);\u003Cbr\u003EБеременность и период грудного вскармливания."},{"name":"Состав","value":"На одну таблетку:\u003Cbr\u003EЯдро\u003Cbr\u003E1 слой:\u003Cbr\u003EДействующее вещество: левоцетиризина дигидрохлорид 5,0 мг;\u003Cbr\u003EВспомогательные вещества: лактозы моногидрат (Таблеттоза 100) 63,5 мг, целлюлоза микрокристаллическая (Avicel PH 102) 30,2 мг, кремния диоксид коллоидный 0,3 мг, магния стеарат 1,0 мг;\u003Cbr\u003E2 слой:\u003Cbr\u003EДействующее вещество: монтелукаст натрия 10,4 мг, эквивалентный монтелукасту 10,0 мг;\u003Cbr\u003EВспомогательные вещества: лактозы моногидрат (Фарматоза 200М) 89,3 мг, целлюлоза микрокристаллическая (Avicel PH 101) 83,2 мг, краситель железа оксид желтый (железа оксид желтый) 0,1мг, кроскармеллоза натрия 13,0 мг, гипролоза (гидроксипропилцеллюлоза) 3,0 мг, магния стеарат 1,0 мг;\u003Cbr\u003EПленочная оболочка\u003Cbr\u003EОпадрай желтый (Опадрай желтый 13В52204) 6,0 мг (гипромеллоза 6сР (НРМС2910) 3,75 мг, титана диоксид 1,4556 мг, макрогол-400 0,375 мг, краситель железа оксид желтый (железа оксид желтый) 0,357 мг, полисорбат-80 0,060 мг, краситель железа оксид красный (железа оксид красный) 0,0024 мг)."},{"name":"Действующее вещество","value":"Левоцетиризин+Монтелукаст"},{"name":"Способ применения и дозы","value":"Внутрь, запивая водой, независимо от приема пищи.\u003Cbr\u003EВзрослым и детям старше 15 лет: принимать по 1 таблетке 1 раз в сутки.\u003Cbr\u003EПациентам с печеночной недостаточностью коррекции дозы не требуется.\u003Cbr\u003EПациентам с хронической почечной недостаточностью и пациентам пожилого возраста следует корректировать дозу в зависимости от степени почечной недостаточности.\u003Cbr\u003EПациентам с легким нарушением функции почек (клиренс креатинина 50-79 мл/мин) коррекции дозы не требуется.\u003Cbr\u003EУ пациентов с умеренной почечной недостаточностью (клиренс креатинина от 30 до 49 мл/мин) рекомендуемая доза левоцетиризина 5 мг (1 таблетка) через день.\u003Cbr\u003EУ пациентов с тяжелой почечной недостаточностью (клиренс креатинина менее 30 мл/мин) рекомендуемая доза левоцетиризина 5 мг (1 таблетка) 1 раз в 3 дня.\u003Cbr\u003EПродолжительность приема препарата\u003Cbr\u003EПри лечении сезонного (интермиттирующего) ринита (наличие симптомов менее 4 дней в неделю или их общая продолжительность менее 4-х недель) продолжительность лечения зависит от длительности симптоматики; лечение может быть прекращено при исчезновении симптомов и возобновлено при появлении симптомов.\u003Cbr\u003EПри лечении круглогодичного (персистирующего) аллергического ринита (наличие симптомов более 4-х дней в неделю и их общая продолжительность более 4-х недель) лечение может продолжаться в течение всего периода воздействия аллергенов.\u003Cbr\u003EПри пропуске одного приема препарата не следует принимать дополнительную дозу препарата для компенсации пропущенного приема, рекомендуется принять следующую дозу в обычное время."},{"name":"Побочные действия","value":"Перечисленные ниже нежелательные явления распределены по частоте возникновения в соответствии со следующей градацией: очень часто (≥ 1/10), часто (от ≥ 1/100 до \u003C 1/10), нечасто (от≥ 1/1000 до \u003C 1/100), редко (от≥ 1/10000 до \u003C 1/1000), очень редко (\u003C 1/10000), частота неизвестна (частота не может быть подсчитана по имеющимся данным).\u003Cbr\u003EМонтелукаст\u003Cbr\u003EНарушения со стороны крови и лимфатической системы: частота неизвестна - повышенная склонность к кровотечениям, тромбоцитопения.\u003Cbr\u003EНарушения со стороны иммунной системы: редко - реакция гиперчувствительности, в том числе анафилаксия, очень редко - эозинофильная инфильтрация печени.\u003Cbr\u003EНарyшения психики: частота неизвестна - ажитация, в том числе агрессивное поведение или враждебность, тревожность, депрессия, дезориентация, патологические сновидения, галлюцинации, бессонница, раздражительность, беспокойство, сомнамбулизм, суицидальные мысли и поведение (суицидальность), тремор, нарушения внимания и памяти.\u003Cbr\u003EНарушения со стороны нервной системы: редко - головная боль, головокружение, сонливость; очень редко - судороги; частота неизвестна - парестезия/гипестезия.\u003Cbr\u003EНарушения со стороны сердца: частота неизвестна - учащенное сердцебиение.\u003Cbr\u003EНарушения со стороны дыхательной системы, органов грудной клетки и средостения: редко - носовое кровотечение, частота неизвестна - инфекции верхних дыхательных путей, фарингит, кашель, синусит, ринорея, синдром Чарджа-Стросса.\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта: редко - изжога, отрыжка, боль в животе; частота неизвестна- диарея, рвота, диспепсия, тошнота, запоры, панкреатит, сухость во рту.\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей: редко - повышение активности \"печеночных\" трансаминаз в сыворотке крови (аланинаминотрансфераза (АЛТ), аспартатаминотрансфераза (ACT)), очень редко - гепатит (включая холестатические, гепатоцеллюлярные и смешанные поражения печени).\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей: редко - кожная сыпь, крапивница; частота неизвестна - ангионевротический отек, появление экхимозов, узловатая эритема, многоформная эритема, кожный зуд.\u003Cbr\u003EНарушения со стороны скелетно-мышечной и соединительной ткани: редко - артралгия; частота неизвестна - миалгия, включая спазмы мышц.\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей: частота неизвестна - энурез у детей.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения: редко - астения (слабость)/усталость; частота неизвестна - отеки, пирексия, жажда.\u003Cbr\u003EЛевоцетиризин\u003Cbr\u003EНарушения со стороны иммунной системы: частота неизвестна - реакции гиперчувствительности, в том числе анафилактические реакции.\u003Cbr\u003EНарушения со стороны обмена веществ и питания: частота неизвестна - повышение аппетита, повышение массы тела.\u003Cbr\u003EНарушения психики: часто - головная боль, сонливость, утомляемость; нечасто - астения; частота неизвестна- тревога, агрессия, возбуждение, бессонница, галлюцинации, депрессия, суицидальные мысли.\u003Cbr\u003EНарушения со стороны нервной системы: частота неизвестна - судороги, тромбоз синусов твердой мозговой оболочки, парестезия, головокружение, обморок, тремор, дисгевзия (нарушение вкуса).\u003Cbr\u003EНарушения со стороны органа зрения: частота неизвестна - нарушение зрения, диплопия, воспаление, нечеткость зрительного восприятия.\u003Cbr\u003EНарушения со стороны органа слуха и лабиринтные нарушения: частота неизвестна - вертиго.\u003Cbr\u003EНарушения со стороны сердца: частота неизвестна - тахикардия, стенокардия, ощущение сердцебиения.\u003Cbr\u003EНарушения со стороны сосудов: частота неизвестна - тромбоз яремной вены.\u003Cbr\u003EНарушения со стороны дыхательной системы, органов грудной клетки и средостения: частота неизвестна - диспноэ, усиление симптомов ринита.\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта: часто - сухость во рту; нечасто - боль в животе; частота неизвестна - тошнота, диарея, рвота.\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей: частота неизвестна - гепатит.\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей: частота неизвестна - ангионевротический отек, стойкая лекарственная эритема, сыпь, зуд, крапивница, гипотрихоз, трещины, фотосенсибилизация.\u003Cbr\u003EНарушения со стороны скелетно-мышечной и соединительной ткани: частота неизвестна - боли в мышцах, артралгия.\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей: частота неизвестна - дизурия, задержка мочи, позывы на мочеиспускание.\u003Cbr\u003EЛабораторные и инструментальные данные: частота неизвестна - изменение функциональных проб печени.\u003Cbr\u003EПрочее: частота неизвестна - перекрестная реактивность, периферические отеки.\u003Cbr\u003EЕсли любые из указанных в инструкции побочных эффектов усугубляются, или Вы заметили любые другие побочные эффекты, не указанные в инструкции, сообщите об этом врачу."},{"name":"Фармакологическое действие","value":"Препарат представляет собой комбинацию монтелукаста (лейкотриеновых рецепторов блокатор) и левоцетиризина (Н1-гистаминовых рецепторов блокатор).\u003Cbr\u003EМонтелукаст селективно ингибирует CysLT-рецепторы цистеиниловых лейкотриенов эпителия дыхательных путей. Цистеинил лейкотриеновые рецепторы 1 типа (CysLT-рецепторы) присутствуют в дыхательных путях человека, в том числе в клетках гладких мышц бронхов, макрофагах и других провоспалительных клетках (включая эозинофилы и некоторые миеловидные стволовые клетки). Цистеинил лейкотриены (LTC4, LTD4, LTE4) относятся к классу эйкозаноидов, образующихся из арахидоновой кислоты, и являются медиаторами воспаления, образующимися в различных клетках организма, в том числе в тучных клетках и эозинофилах.\u003Cbr\u003EЦистеинил лейкотриены коррелируют с патофизиологией бронхиальной астмы и аллергического ринита.\u003Cbr\u003EПри аллергическом рините после воздействия аллергена происходит высвобождение цистеинил лейкотриенов из противовоспалительных клеток слизистой оболочки полости носа во время ранней и поздней фаз аллергической реакции, что проявляется симптомами аллергического ринита. При интраназальной пробе с цистеинил лейкотриенами было продемонстрировано повышение симптомов назальной обструкции. Монтелукаст с высоким сродством и избирательностью связывается с CysLT1-рецепторами, снижает число эозинофилов в периферической крови, в дыхательных путях.\u003Cbr\u003EЛевоцетиризин - R-энантиомер цетиризина; конкурентный антагонист гистамина; блокирует Н1-гистаминовые рецепторы, сродство к которым в 2 раза выше, чем у цетиризина. Левоцетиризин оказывает влияние на гистаминозависимую стадию аллергических реакций; уменьшает миграцию эозинофилов, уменьшает сосудистую проницаемость, ограничивает высвобождение медиаторов воспаления и цитокинов (VCAM-1 и других).\u003Cbr\u003EЛевоцетиризин предупреждает развитие и облегчает течение аллергических реакций, оказывает антиэкссудативное, противозудное действие; практически не оказывает антихолинергического и антисеротонинового действия. В терапевтических дозах практически не оказывает седативного действия.\u003Cbr\u003EДействие начинается через 12 минут после приема однократной дозы у 50% пациентов, через 1 час - у 95% и продолжается в течение 24 часов."},{"name":"Фармакологическая группа","value":"Лейкотриеновых рецепторов блокатор+Н1-гистаминовых рецепторов блокатор"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 15 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"Хранить в защищенном от света месте, при температуре не выше 25 °С.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"Данных о передозировке препаратом не поступало. Однако имеются данные о передозировке отдельными компонентами препарата.\u003Cbr\u003EМонтелукаст\u003Cbr\u003EСимптомы: Наиболее частыми нежелательными явлениями были чувство жажды, сонливость, рвота, психомоторное возбуждение, головная боль и боль в животе.\u003Cbr\u003EЛечение: лечение симптоматическое. Отсутствует информация о специфическом лечении передозировки монтелукастом. Данных о возможности выведения монтелукаста путем перитонеального диализа и гемодиализа нет.\u003Cbr\u003EЛевоцетиризин\u003Cbr\u003EСимптомы: сонливость (у взрослых), возбуждение и беспокойство, сменяющиеся сонливостью (у детей).\u003Cbr\u003EЛечение: промывание желудка, прием активированного угля, симптоматическая терапия. Специфического антидота нет. Гемодиализ неэффективен."},{"name":"Применение при беременности и кормлении грудью","value":"Адекватных и строго контролируемых клинических исследований по безопасности применения препарата во время беременности не проводилось.\u003Cbr\u003EПрименение препарата при беременности противопоказано.\u003Cbr\u003EДанных о выделении монтелукаста с грудным молоком у человека нет.\u003Cbr\u003EЛевоцетиризин выделяется с грудным молоком. Поэтому при необходимости применения препарата при лактации рекомендуется прекратить грудное вскармливание."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Исследований воздействия препарата на способность управлять транспортными средствами и механизмами не проводилось. В период лечения необходимо соблюдать осторожность при вождении автотранспорта и занятии другими потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций, так как препарат может вызывать слабость, сонливость и головокружение."},{"name":"Особые указания","value":"Монтелукаст\u003Cbr\u003EВ редких случаях у пациентов, принимающих препараты для лечения бронхиальной астмы, включая монтелукаст, может возникнуть системная эозинофилия, иногда сопровождающаяся клиническими проявлениями васкулита и синдрома Чарджа-Стросса. Такое состояние обычно лечат системными глюкокортикостероидами. Такие случаи обычно, но не всегда, связаны с уменьшением дозы или отменой пероральных глюкокортикостероидов. Врачи должны знать о возможности возникновения у пациентов эозинофилии, васкулитной сыпи, нарастания легочных симптомов, осложнений со стороны сердца и/или нейропатии.\u003Cbr\u003EПациенты с подтвержденной аллергией к ацетилсалициловой кислоте и другим нестероидным противовоспалительным препаратам (НПВП) не должны принимать эти препараты в период лечения монтелукастом, поскольку он, улучшая дыхательную функцию у пациентов с аллергической бронхиальной астмой, тем не менее, не может полностью предотвратить бронхоконстрикцию, вызванную НПВП.\u003Cbr\u003EУ пациентов, принимавших монтелукаст, были описаны психоневрологические нарушения. Учитывая, что эти симптомы могли быть вызваны другими факторами, неизвестно, связаны ли они с приемом монтелукаста. Врачу необходимо обсудить данные нежелательные явления с пациентами и/или их родителями/опекунами. Пациентам и/или их родителям/опекунам необходимо объяснить, что в случае появления подобных симптомов необходимо сообщить об этом лечащему врачу.\u003Cbr\u003EЛевоцетиризин\u003Cbr\u003EВо время лечения препаратом не рекомендуется принимать этанол."},{"name":"Взаимодействие","value":"Монтелукаст\u003Cbr\u003EМонтелукаст можно назначать вместе с другими лекарственными средствами, традиционно применяемыми для профилактики и длительного лечения бронхиальной астмы и/или аллергического ринита. Рекомендуемая терапевтическая доза монтелукаста не оказывает клинически значимого влияния на фармакокинетику следующих препаратов: теофиллина. преднизона, преднизолона, пероральных контрацептивов (этинилэстрадиол/норэтистерон 35/1), терфенадина, дигоксина и варфарина.\u003Cbr\u003EЗначение AUC снижается при одновременном приеме фенобарбитала (примерно на 40%), однако коррекция режима дозирования монтелукаста не требуется. Поскольку монтелукаст метаболизируется изоферментом CYP 3А4 следует соблюдать осторожность, если монтелукаст одновременно назначается с препаратами, индуцирующими изофермент CYP 3А4, такими как фенитоин, фенобарбитал и рифампицин. Однако изменения дозы монтелукаста не требуется.\u003Cbr\u003EИсследования in vitro показали, что монтелукаст является потенциальным ингибитором изофермента CYP 2С8, однако данные клинических исследований взаимодействия препарат- препарат, включающих монтелукаст и росиглитазон (предварительный субстрат представителя медицинских препаратов, первично метаболизирующихся изоферментом CYP 2С8) показали, что дозы монтелукаста не ингибируют изоферменты CYP 2С8 in vivo. Следовательно, монтелукаст не оказывает заметного влияния на метаболизм препаратов, метаболизирующихся этим ферментом (например, паклитаксел, росиглитазон и репаглинид).\u003Cbr\u003EГемфиброзил (ингибитор CYP 2С8 и 2С9) повышает эффект системного воздействия монтелукаста в 4,4 раза. Однако влияние гемфиброзила на системное воздействие монтелукаста не может считаться клинически значимым на основании данных по безопасности при применении монтелукаста в дозах, превышающих одобренную дозу 10 мг. Поэтому при совместном приеме вместе с гемфиброзилом коррекция дозы монтелукаста не требуется.\u003Cbr\u003EСовместный прием итраконазола, мощного ингибитора CYP 3А4, вместе с гемфиброзилом и монтелукастом не приводил к дополнительному повышению эффекта системного воздействия монтелукаста.\u003Cbr\u003EЛевоцетиризин\u003Cbr\u003EПри изучении лекарственного взаимодействия рацемата цетиризина с феназоном, псевдоэфедрином, циметидином, кетоконазолом, эритромицином, азитромицином, глипизидом и диазепамом клинически значимых нежелательных взаимодействий не выявлено.\u003Cbr\u003EТеофиллин (400 мг/сутки) снижает общий клиренс левоцетиризина на 16%, при этом кинетика теофиллина не изменяется.\u003Cbr\u003EВ исследовании при одновременном приеме ритонавира (600 мг 2 раза в сутки) и цетиризина (10 мг в сутки) показано, что экспозиция цетиризина увеличивалась на 40%, а экспозиция ритонавира незначительно изменялась (-11%).\u003Cbr\u003EСовместное применение с макролидами или кетоконазолом не вызывало достоверных изменений на ЭКГ.\u003Cbr\u003EВ ряде случаев при одновременном применении левоцетиризина с алкоголем или лекарственными препаратами, оказывающими подавляющее влияние на центральную нервную систему (ЦНС), возможно усиление их влияния на ЦНС, хотя не доказано, что рацемат цетиризина потенцирует эффект алкоголя."},{"name":"Регистрационный номер","value":"ЛП-005772"},{"name":"Дата государственной регистрации","value":"04.09.2019"},{"name":"Владелец регистрационного удостоверения","value":"Glenmark"},{"name":"Изготовитель","value":"Glenmark Pharmaceuticals Ltd."},{"name":"Фасовщик","value":"Glenmark"},{"name":"Страна бренда","value":"Индия"},{"name":"Страна-производитель","value":"Индия"},{"name":"Название препарата","value":"Монтлезир"},{"name":"Срок годности","value":"23 мес."}]}],"transitionId":"tr_11023771645938464775"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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производным пиперазина), а также к другим компонентам препарата;\u003Cbr\u003EДефицит лактазы, непереносимость лактозы, глюкозо-галактозная мальабсорбция;\u003Cbr\u003EТерминальная стадия почечной недостаточности (клиренс креатинина ниже 10 мл/мин);\u003Cbr\u003EДетский возраст до 15 лет (ввиду ограниченности данных по безопасности и эффективности);\u003Cbr\u003EБеременность и период грудного вскармливания."},{"description":"","filters":[{"id":15768292,"name":"Состав"}],"isMainProperty":false,"name":"Состав","value":"На одну таблетку:\u003Cbr\u003EЯдро\u003Cbr\u003E1 слой:\u003Cbr\u003EДействующее вещество: левоцетиризина дигидрохлорид 5,0 мг;\u003Cbr\u003EВспомогательные вещества: лактозы моногидрат (Таблеттоза 100) 63,5 мг, целлюлоза микрокристаллическая (Avicel PH 102) 30,2 мг, кремния диоксид коллоидный 0,3 мг, магния стеарат 1,0 мг;\u003Cbr\u003E2 слой:\u003Cbr\u003EДействующее вещество: монтелукаст натрия 10,4 мг, эквивалентный монтелукасту 10,0 мг;\u003Cbr\u003EВспомогательные вещества: лактозы моногидрат (Фарматоза 200М) 89,3 мг, целлюлоза микрокристаллическая (Avicel PH 101) 83,2 мг, краситель железа оксид желтый (железа оксид желтый) 0,1мг, кроскармеллоза натрия 13,0 мг, гипролоза (гидроксипропилцеллюлоза) 3,0 мг, магния стеарат 1,0 мг;\u003Cbr\u003EПленочная оболочка\u003Cbr\u003EОпадрай желтый (Опадрай желтый 13В52204) 6,0 мг (гипромеллоза 6сР (НРМС2910) 3,75 мг, титана диоксид 1,4556 мг, макрогол-400 0,375 мг, краситель железа оксид желтый (железа оксид желтый) 0,357 мг, полисорбат-80 0,060 мг, краситель железа оксид красный (железа оксид красный) 0,0024 мг)."},{"description":"","filters":[{"id":27144131,"name":"Действующее вещество"}],"isMainProperty":false,"name":"Действующее вещество","value":"Левоцетиризин+Монтелукаст"},{"description":"","filters":[{"id":15768000,"name":"Способ применения и дозы"}],"isMainProperty":false,"name":"Способ применения и дозы","value":"Внутрь, запивая водой, независимо от приема пищи.\u003Cbr\u003EВзрослым и детям старше 15 лет: принимать по 1 таблетке 1 раз в сутки.\u003Cbr\u003EПациентам с печеночной недостаточностью коррекции дозы не требуется.\u003Cbr\u003EПациентам с хронической почечной недостаточностью и пациентам пожилого возраста следует корректировать дозу в зависимости от степени почечной недостаточности.\u003Cbr\u003EПациентам с легким нарушением функции почек (клиренс креатинина 50-79 мл/мин) коррекции дозы не требуется.\u003Cbr\u003EУ пациентов с умеренной почечной недостаточностью (клиренс креатинина от 30 до 49 мл/мин) рекомендуемая доза левоцетиризина 5 мг (1 таблетка) через день.\u003Cbr\u003EУ пациентов с тяжелой почечной недостаточностью (клиренс креатинина менее 30 мл/мин) рекомендуемая доза левоцетиризина 5 мг (1 таблетка) 1 раз в 3 дня.\u003Cbr\u003EПродолжительность приема препарата\u003Cbr\u003EПри лечении сезонного (интермиттирующего) ринита (наличие симптомов менее 4 дней в неделю или их общая продолжительность менее 4-х недель) продолжительность лечения зависит от длительности симптоматики; лечение может быть прекращено при исчезновении симптомов и возобновлено при появлении симптомов.\u003Cbr\u003EПри лечении круглогодичного (персистирующего) аллергического ринита (наличие симптомов более 4-х дней в неделю и их общая продолжительность более 4-х недель) лечение может продолжаться в течение всего периода воздействия аллергенов.\u003Cbr\u003EПри пропуске одного приема препарата не следует принимать дополнительную дозу препарата для компенсации пропущенного приема, рекомендуется принять следующую дозу в обычное время."},{"description":"","filters":[{"id":15767998,"name":"Побочные действия"}],"isMainProperty":false,"name":"Побочные действия","value":"Перечисленные ниже нежелательные явления распределены по частоте возникновения в соответствии со следующей градацией: очень часто (≥ 1/10), часто (от ≥ 1/100 до \u003C 1/10), нечасто (от≥ 1/1000 до \u003C 1/100), редко (от≥ 1/10000 до \u003C 1/1000), очень редко (\u003C 1/10000), частота неизвестна (частота не может быть подсчитана по имеющимся данным).\u003Cbr\u003EМонтелукаст\u003Cbr\u003EНарушения со стороны крови и лимфатической системы: частота неизвестна - повышенная склонность к кровотечениям, тромбоцитопения.\u003Cbr\u003EНарушения со стороны иммунной системы: редко - реакция гиперчувствительности, в том числе анафилаксия, очень редко - эозинофильная инфильтрация печени.\u003Cbr\u003EНарyшения психики: частота неизвестна - ажитация, в том числе агрессивное поведение или враждебность, тревожность, депрессия, дезориентация, патологические сновидения, галлюцинации, бессонница, раздражительность, беспокойство, сомнамбулизм, суицидальные мысли и поведение (суицидальность), тремор, нарушения внимания и памяти.\u003Cbr\u003EНарушения со стороны нервной системы: редко - головная боль, головокружение, сонливость; очень редко - судороги; частота неизвестна - парестезия/гипестезия.\u003Cbr\u003EНарушения со стороны сердца: частота неизвестна - учащенное сердцебиение.\u003Cbr\u003EНарушения со стороны дыхательной системы, органов грудной клетки и средостения: редко - носовое кровотечение, частота неизвестна - инфекции верхних дыхательных путей, фарингит, кашель, синусит, ринорея, синдром Чарджа-Стросса.\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта: редко - изжога, отрыжка, боль в животе; частота неизвестна- диарея, рвота, диспепсия, тошнота, запоры, панкреатит, сухость во рту.\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей: редко - повышение активности \"печеночных\" трансаминаз в сыворотке крови (аланинаминотрансфераза (АЛТ), аспартатаминотрансфераза (ACT)), очень редко - гепатит (включая холестатические, гепатоцеллюлярные и смешанные поражения печени).\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей: редко - кожная сыпь, крапивница; частота неизвестна - ангионевротический отек, появление экхимозов, узловатая эритема, многоформная эритема, кожный зуд.\u003Cbr\u003EНарушения со стороны скелетно-мышечной и соединительной ткани: редко - артралгия; частота неизвестна - миалгия, включая спазмы мышц.\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей: частота неизвестна - энурез у детей.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения: редко - астения (слабость)/усталость; частота неизвестна - отеки, пирексия, жажда.\u003Cbr\u003EЛевоцетиризин\u003Cbr\u003EНарушения со стороны иммунной системы: частота неизвестна - реакции гиперчувствительности, в том числе анафилактические реакции.\u003Cbr\u003EНарушения со стороны обмена веществ и питания: частота неизвестна - повышение аппетита, повышение массы тела.\u003Cbr\u003EНарушения психики: часто - головная боль, сонливость, утомляемость; нечасто - астения; частота неизвестна- тревога, агрессия, возбуждение, бессонница, галлюцинации, депрессия, суицидальные мысли.\u003Cbr\u003EНарушения со стороны нервной системы: частота неизвестна - судороги, тромбоз синусов твердой мозговой оболочки, парестезия, головокружение, обморок, тремор, дисгевзия (нарушение вкуса).\u003Cbr\u003EНарушения со стороны органа зрения: частота неизвестна - нарушение зрения, диплопия, воспаление, нечеткость зрительного восприятия.\u003Cbr\u003EНарушения со стороны органа слуха и лабиринтные нарушения: частота неизвестна - вертиго.\u003Cbr\u003EНарушения со стороны сердца: частота неизвестна - тахикардия, стенокардия, ощущение сердцебиения.\u003Cbr\u003EНарушения со стороны сосудов: частота неизвестна - тромбоз яремной вены.\u003Cbr\u003EНарушения со стороны дыхательной системы, органов грудной клетки и средостения: частота неизвестна - диспноэ, усиление симптомов ринита.\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта: часто - сухость во рту; нечасто - боль в животе; частота неизвестна - тошнота, диарея, рвота.\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей: частота неизвестна - гепатит.\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей: частота неизвестна - ангионевротический отек, стойкая лекарственная эритема, сыпь, зуд, крапивница, гипотрихоз, трещины, фотосенсибилизация.\u003Cbr\u003EНарушения со стороны скелетно-мышечной и соединительной ткани: частота неизвестна - боли в мышцах, артралгия.\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей: частота неизвестна - дизурия, задержка мочи, позывы на мочеиспускание.\u003Cbr\u003EЛабораторные и инструментальные данные: частота неизвестна - изменение функциональных проб печени.\u003Cbr\u003EПрочее: частота неизвестна - перекрестная реактивность, периферические отеки.\u003Cbr\u003EЕсли любые из указанных в инструкции побочных эффектов усугубляются, или Вы заметили любые другие побочные эффекты, не указанные в инструкции, сообщите об этом врачу."},{"description":"","filters":[{"id":15768001,"name":"Фармакологическое действие"}],"isMainProperty":false,"name":"Фармакологическое действие","value":"Препарат представляет собой комбинацию монтелукаста (лейкотриеновых рецепторов блокатор) и левоцетиризина (Н1-гистаминовых рецепторов блокатор).\u003Cbr\u003EМонтелукаст селективно ингибирует CysLT-рецепторы цистеиниловых лейкотриенов эпителия дыхательных путей. Цистеинил лейкотриеновые рецепторы 1 типа (CysLT-рецепторы) присутствуют в дыхательных путях человека, в том числе в клетках гладких мышц бронхов, макрофагах и других провоспалительных клетках (включая эозинофилы и некоторые миеловидные стволовые клетки). Цистеинил лейкотриены (LTC4, LTD4, LTE4) относятся к классу эйкозаноидов, образующихся из арахидоновой кислоты, и являются медиаторами воспаления, образующимися в различных клетках организма, в том числе в тучных клетках и эозинофилах.\u003Cbr\u003EЦистеинил лейкотриены коррелируют с патофизиологией бронхиальной астмы и аллергического ринита.\u003Cbr\u003EПри аллергическом рините после воздействия аллергена происходит высвобождение цистеинил лейкотриенов из противовоспалительных клеток слизистой оболочки полости носа во время ранней и поздней фаз аллергической реакции, что проявляется симптомами аллергического ринита. При интраназальной пробе с цистеинил лейкотриенами было продемонстрировано повышение симптомов назальной обструкции. Монтелукаст с высоким сродством и избирательностью связывается с CysLT1-рецепторами, снижает число эозинофилов в периферической крови, в дыхательных путях.\u003Cbr\u003EЛевоцетиризин - R-энантиомер цетиризина; конкурентный антагонист гистамина; блокирует Н1-гистаминовые рецепторы, сродство к которым в 2 раза выше, чем у цетиризина. Левоцетиризин оказывает влияние на гистаминозависимую стадию аллергических реакций; уменьшает миграцию эозинофилов, уменьшает сосудистую проницаемость, ограничивает высвобождение медиаторов воспаления и цитокинов (VCAM-1 и других).\u003Cbr\u003EЛевоцетиризин предупреждает развитие и облегчает течение аллергических реакций, оказывает антиэкссудативное, противозудное действие; практически не оказывает антихолинергического и антисеротонинового действия. В терапевтических дозах практически не оказывает седативного действия.\u003Cbr\u003EДействие начинается через 12 минут после приема однократной дозы у 50% пациентов, через 1 час - у 95% и продолжается в течение 24 часов."},{"description":"","filters":[{"id":34045110,"name":"Фармакологическая группа"}],"isMainProperty":false,"name":"Фармакологическая группа","value":"Лейкотриеновых рецепторов блокатор+Н1-гистаминовых рецепторов блокатор"},{"description":"","filters":[{"id":27141511,"name":"Форма выпуска для карточки"}],"isMainProperty":false,"name":"Форма выпуска","value":"таблетки"},{"description":"","filters":[{"id":35947170,"name":"Способ применения/введения"}],"isMainProperty":false,"name":"Способ применения/введения","value":"пероральный"},{"description":"","filters":[{"id":23679511,"name":"Минимальный возраст применения"},{"id":16082123,"name":"С рождения"}],"isMainProperty":false,"name":"Минимальный возраст применения","value":"от 15 лет"}]},{"name":"Дополнительно","specs":[{"description":"","filters":[{"id":15767999,"name":"Условия хранения"}],"isMainProperty":false,"name":"Условия хранения","value":"Хранить в защищенном от света месте, при температуре не выше 25 °С.\u003Cbr\u003EХранить в недоступном для детей месте."},{"description":"","filters":[{"id":15768014,"name":"Передозировка"}],"isMainProperty":false,"name":"Передозировка","value":"Данных о передозировке препаратом не поступало. Однако имеются данные о передозировке отдельными компонентами препарата.\u003Cbr\u003EМонтелукаст\u003Cbr\u003EСимптомы: Наиболее частыми нежелательными явлениями были чувство жажды, сонливость, рвота, психомоторное возбуждение, головная боль и боль в животе.\u003Cbr\u003EЛечение: лечение симптоматическое. Отсутствует информация о специфическом лечении передозировки монтелукастом. Данных о возможности выведения монтелукаста путем перитонеального диализа и гемодиализа нет.\u003Cbr\u003EЛевоцетиризин\u003Cbr\u003EСимптомы: сонливость (у взрослых), возбуждение и беспокойство, сменяющиеся сонливостью (у детей).\u003Cbr\u003EЛечение: промывание желудка, прием активированного угля, симптоматическая терапия. Специфического антидота нет. Гемодиализ неэффективен."},{"description":"","filters":[{"id":15768015,"name":"Применение при беременности и кормлении грудью"}],"isMainProperty":false,"name":"Применение при беременности и кормлении грудью","value":"Адекватных и строго контролируемых клинических исследований по безопасности применения препарата во время беременности не проводилось.\u003Cbr\u003EПрименение препарата при беременности противопоказано.\u003Cbr\u003EДанных о выделении монтелукаста с грудным молоком у человека нет.\u003Cbr\u003EЛевоцетиризин выделяется с грудным молоком. Поэтому при необходимости применения препарата при лактации рекомендуется прекратить грудное вскармливание."},{"description":"","filters":[{"id":17360993,"name":"Влияние на способность управлять транспортом и механизмами"}],"isMainProperty":false,"name":"Влияние на способность управлять транспортом и механизмами","value":"Исследований воздействия препарата на способность управлять транспортными средствами и механизмами не проводилось. В период лечения необходимо соблюдать осторожность при вождении автотранспорта и занятии другими потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций, так как препарат может вызывать слабость, сонливость и головокружение."},{"description":"","filters":[{"id":15771167,"name":"Особые указания"}],"isMainProperty":false,"name":"Особые указания","value":"Монтелукаст\u003Cbr\u003EВ редких случаях у пациентов, принимающих препараты для лечения бронхиальной астмы, включая монтелукаст, может возникнуть системная эозинофилия, иногда сопровождающаяся клиническими проявлениями васкулита и синдрома Чарджа-Стросса. Такое состояние обычно лечат системными глюкокортикостероидами. Такие случаи обычно, но не всегда, связаны с уменьшением дозы или отменой пероральных глюкокортикостероидов. Врачи должны знать о возможности возникновения у пациентов эозинофилии, васкулитной сыпи, нарастания легочных симптомов, осложнений со стороны сердца и/или нейропатии.\u003Cbr\u003EПациенты с подтвержденной аллергией к ацетилсалициловой кислоте и другим нестероидным противовоспалительным препаратам (НПВП) не должны принимать эти препараты в период лечения монтелукастом, поскольку он, улучшая дыхательную функцию у пациентов с аллергической бронхиальной астмой, тем не менее, не может полностью предотвратить бронхоконстрикцию, вызванную НПВП.\u003Cbr\u003EУ пациентов, принимавших монтелукаст, были описаны психоневрологические нарушения. Учитывая, что эти симптомы могли быть вызваны другими факторами, неизвестно, связаны ли они с приемом монтелукаста. Врачу необходимо обсудить данные нежелательные явления с пациентами и/или их родителями/опекунами. 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Рекомендуемая терапевтическая доза монтелукаста не оказывает клинически значимого влияния на фармакокинетику следующих препаратов: теофиллина. преднизона, преднизолона, пероральных контрацептивов (этинилэстрадиол/норэтистерон 35/1), терфенадина, дигоксина и варфарина.\u003Cbr\u003EЗначение AUC снижается при одновременном приеме фенобарбитала (примерно на 40%), однако коррекция режима дозирования монтелукаста не требуется. Поскольку монтелукаст метаболизируется изоферментом CYP 3А4 следует соблюдать осторожность, если монтелукаст одновременно назначается с препаратами, индуцирующими изофермент CYP 3А4, такими как фенитоин, фенобарбитал и рифампицин. 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Поэтому при совместном приеме вместе с гемфиброзилом коррекция дозы монтелукаста не требуется.\u003Cbr\u003EСовместный прием итраконазола, мощного ингибитора CYP 3А4, вместе с гемфиброзилом и монтелукастом не приводил к дополнительному повышению эффекта системного воздействия монтелукаста.\u003Cbr\u003EЛевоцетиризин\u003Cbr\u003EПри изучении лекарственного взаимодействия рацемата цетиризина с феназоном, псевдоэфедрином, циметидином, кетоконазолом, эритромицином, азитромицином, глипизидом и диазепамом клинически значимых нежелательных взаимодействий не выявлено.\u003Cbr\u003EТеофиллин (400 мг/сутки) снижает общий клиренс левоцетиризина на 16%, при этом кинетика теофиллина не изменяется.\u003Cbr\u003EВ исследовании при одновременном приеме ритонавира (600 мг 2 раза в сутки) и цетиризина (10 мг в сутки) показано, что экспозиция цетиризина увеличивалась на 40%, а экспозиция ритонавира незначительно изменялась (-11%).\u003Cbr\u003EСовместное применение с макролидами или кетоконазолом не 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  • Монтрал МЛ таб. п/о плен., 5 мг+10 мг, 30 шт.
    –21 %
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    Монтрал МЛ таб. п/о плен., 5 мг+10 мг, 30 шт.

    Рейтинг товара: 4.8 из 5
    на основе 33 оценки
    Цена 908 ₽ вместо 1 150
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  • Монтелукаст таб. п/о плен., 10 мг, 30 шт.
    –21 %
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    Монтелукаст таб. п/о плен., 10 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 50 оценок
    Цена 659 ₽ вместо 835
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  • Монтелукаст-ВЕРТЕКС таб. п/о плен., 10 мг, 30 шт.
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    Монтелукаст-ВЕРТЕКС таб. п/о плен., 10 мг, 30 шт.

    Рейтинг товара: 4.7 из 5
    на основе 73 оценки
    Цена 903 ₽
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  • Глемонт таб. жев., 5 мг, 28 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-apt4pa4d9vl/toggleWishlist":{"skuId":"453473056","productId":1436721451,"offerId":"ryfnL0oy_8ju0-2gBDhceQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ26bi8bX/+aYtEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYIq8KKrQUQoOad2AEY/dzQByDh3MEH","sign":"sWXibJFw7cY10l8KxoP215i0W2tReULNLMJ/vDdbXJ0="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-apt4pa4d9vl/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Глемонт таб. жев., 5 мг, 28 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 1 241 ₽
    {"widgets":{"@light/AddToCartButtonSnippet":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-apt4pa4d9vl/addToCartButton":{"offerId":"ryfnL0oy_8ju0-2gBDhceQ","skuId":"453473056","pendingCartItem":{"productId":1436721451,"offerId":"ryfnL0oy_8ju0-2gBDhceQ","showPlaceId":"OTNDnItfwRMjN9MRHuEMMkvtjrW7NWkq1_M8grcB_NIgKDjPFIxJRTB9U8wug9qOwqHurksWfRLWu3860qZoqPgt-B_URfxpOCLf5tWe6cdKn07qdRWWLPcbu2L0RKusnpkUKJKZPAzlH6al5JK7YJGlRXf1X-4T39SHysiIESZoC6zsWIUADEWvw09I1XtvQk58a-uKke_lkpeiIeBHcw,,","feeShow":"OTNDnItfwRMjN9MRHuEMMkvtjrW7NWkq1_M8grcB_NIgKDjPFIxJRTB9U8wug9qOwqHurksWfRLWu3860qZoqPgt-B_URfxpOCLf5tWe6cdKn07qdRWWLPcbu2L0RKusnpkUKJKZPAzlH6al5JK7YJGlRXf1X-4T39SHysiIESZoC6zsWIUADEWvw09I1XtvQk58a-uKke_lkpeiIeBHcw,,","skuId":"453473056","shopId":55106433,"price":{"applicablePriceDiscounts":[],"value":"1241","currency":"RUR"},"hid":"15756897","name":"Глемонт таб. жев., 5 мг, 28 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  • Монтелар таб. п/о плен., 10 мг, 28 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-nytns37hl7j/toggleWishlist":{"skuId":"453474085","productId":1436721452,"offerId":"8wYvrgOo0FPpZyZPJiR0Jw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ26bi8bX/+aYtEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYIrMKKrQUQpe6d2AEYxJzQByDh3MEH","sign":"eAX4Feo61gg2cnSCSFYeKnk0ilINiMcJz0OdVoe9PEE="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-nytns37hl7j/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Монтелар таб. п/о плен., 10 мг, 28 шт.

    Рейтинг товара: 4.8 из 5
    на основе 4 оценки
    Цена 1 099 ₽
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  • Респисальф капс. с пор. д/инг., 50 мкг+500 мкг/доза, 60 шт.
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    Респисальф капс. с пор. д/инг., 50 мкг+500 мкг/доза, 60 шт.

    Цена 1 692 ₽
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  • Кленил УДВ сусп. д/инг. дозир. доз, 800 мкг/2 мл, 20 шт.
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    Кленил УДВ сусп. д/инг. дозир. доз, 800 мкг/2 мл, 20 шт.

    Рейтинг товара: 4.9 из 5
    на основе 14 оценок
    Цена 894 ₽
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  • Эуфиллин таб., 150 мг, 30 шт.
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    Эуфиллин таб., 150 мг, 30 шт.

    Цена 29 ₽
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  • Сибри Бризхалер капс. с пор. д/инг. с устр. д/ингаляций (бризхалер), 50 мкг, 30 шт.
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    Сибри Бризхалер капс. с пор. д/инг. с устр. д/ингаляций (бризхалер), 50 мкг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 3 оценки
    Цена 1 988 ₽
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  • Треледжи Эллипта пор д/инг. доз., 22 мкг+55 мкг+92 мкг/доза, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-zlj5m5lhtz/toggleWishlist":{"skuId":"101612036790","productId":835488048,"offerId":"9Y76AGsoTUQwQ65l6Lf99w","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ26bi8bX/+aYtEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIsJKyjgMQtsWyxPoCGMfGnggg4dzBBw==","sign":"uxhJN8lymW2D1xYyec8P0lGUUiOTWT/u6vTL/hCBhZY="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-zlj5m5lhtz/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Треледжи Эллипта пор д/инг. доз., 22 мкг+55 мкг+92 мкг/доза, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 3 оценки
    Цена 4 624 ₽
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  • Алмонт таб. п/о плен., 10 мг, 28 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-vlcgzenpaq/toggleWishlist":{"skuId":"186989670","productId":1436721426,"offerId":"j5Slf24S8vtziLma3NDCUw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ26bi8bX/+aYtEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIksKKrQUQ5viUWRjGrowRIOHcwQc=","sign":"wqjbdp5NRJwQs2iszcRn22iTyU3H/HCH1gBmk8j1vuI="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-vlcgzenpaq/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Алмонт таб. п/о плен., 10 мг, 28 шт.

    Рейтинг товара: 5 из 5
    на основе 3 оценки
    Цена 1 349 ₽
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Инструкция

Показания к применению

Лечение симптомов круглогодичного (персистирующего) и сезонного (интермиттирующего) аллергических ринитов.

Противопоказания

Повышенная чувствительность к монтелукасту, левоцетиризину (в том числе к производным пиперазина), а также к другим компонентам препарата;
Дефицит лактазы, непереносимость лактозы, глюкозо-галактозная мальабсорбция;
Терминальная стадия почечной недостаточности (клиренс креатинина ниже 10 мл/мин);
Детский возраст до 15 лет (ввиду ограниченности данных по безопасности и эффективности);
Беременность и период грудного вскармливания.

Способ применения и дозы

Внутрь, запивая водой, независимо от приема пищи.
Взрослым и детям старше 15 лет: принимать по 1 таблетке 1 раз в сутки.
Пациентам с печеночной недостаточностью коррекции дозы не требуется.
Пациентам с хронической почечной недостаточностью и пациентам пожилого возраста следует корректировать дозу в зависимости от степени почечной недостаточности.
Пациентам с легким нарушением функции почек (клиренс креатинина 50-79 мл/мин) коррекции дозы не требуется.
У пациентов с умеренной почечной недостаточностью (клиренс креатинина от 30 до 49 мл/мин) рекомендуемая доза левоцетиризина 5 мг (1 таблетка) через день.
У пациентов с тяжелой почечной недостаточностью (клиренс креатинина менее 30 мл/мин) рекомендуемая доза левоцетиризина 5 мг (1 таблетка) 1 раз в 3 дня.
Продолжительность приема препарата
При лечении сезонного (интермиттирующего) ринита (наличие симптомов менее 4 дней в неделю или их общая продолжительность менее 4-х недель) продолжительность лечения зависит от длительности симптоматики; лечение может быть прекращено при исчезновении симптомов и возобновлено при появлении симптомов.
При лечении круглогодичного (персистирующего) аллергического ринита (наличие симптомов более 4-х дней в неделю и их общая продолжительность более 4-х недель) лечение может продолжаться в течение всего периода воздействия аллергенов.
При пропуске одного приема препарата не следует принимать дополнительную дозу препарата для компенсации пропущенного приема, рекомендуется принять следующую дозу в обычное время.
Полная инструкция
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Монтлезир таб. п/о плен.
Монтлезир таб. п/о плен., 30 шт.
5.0
(11)
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1 вопрос
Инструкция

1 340 ₽

Скидка: 6%
–6 %
Вместо:1 423 ₽
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5.0
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У продавца:11 оценок·3 отзыва
У всех продавцов:54 оценки·17 отзывов
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user avatar
Месяц назад • Александр • Куплен на Маркете
Достоинства: Отлично помогает от весенней аллергии на березу
user avatar
7 месяцев назад • Виктория Щербина • Куплен на Маркете
Комментарий: Удобно пить, небольшие гладкие безвкусные таблетки. Назначили в составе комплексного лечения при бронхиальной обструкции. Собственно, эффект есть, перестала кашлять.
user avatar
8 месяцев назад • Иван Гнитеев • Куплен на Маркете
Достоинства: соответствует заявленному описанию
Недостатки: навигация к аптеке в программе ужасная. Очень сложно найти.
Посмотреть все отзывы на Маркете
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Эффективные ингаляторы со скидкой

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    VETTA / Таблетница-органайзер для таблеток аптечка для лекарств карманная в дорогу с разделителем на 14 секций, на неделю 7 дней, утро вечер

    Цена 245 ₽ вместо 1 400
  • Монтелукаст таб. п/о плен., 10 мг, 30 шт.
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    Монтелукаст таб. п/о плен., 10 мг, 30 шт.

    Цена 659 ₽ вместо 835
  • Таблетница на 7 дней 3 приема черная
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    Таблетница на 7 дней 3 приема черная

    Цена 733 ₽ вместо 1 000
  • Таблетница из 14 секций на семь дней Утро-вечер
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    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1883422910_4/content/content/toggleWishlist":{"skuId":"102066600726","productId":1883422910,"offerId":"G5YJqsmMzlSRFHqtJ4bYlg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ26bi8bX/+aYtEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCL6Bi4IHEJb2kp38AhicnfkEIM3OPQ==","sign":"7Xx8BLBA1A88D24euwGRJta+XqjjlT5Bi1p7DXwE0xk="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1883422910_4/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Таблетница из 14 секций на семь дней Утро-вечер

    Цена 166 ₽ вместо 190
  • Монтелукаст-ВЕРТЕКС таб. п/о плен., 10 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:228061358_5/content/content/gallery":{"title":"Монтелукаст-ВЕРТЕКС таб. п/о плен., 10 мг, 30 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/4544730/img_id9205331800947742867.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4544730/img_id9205331800947742867.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4544730/img_id9205331800947742867.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4544730/img_id9205331800947742867.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4544730/img_id9205331800947742867.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4544730/img_id9205331800947742867.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/6175580/img_id5948502795605553414.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/6175580/img_id5948502795605553414.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/6175580/img_id5948502795605553414.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/6175580/img_id5948502795605553414.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/6175580/img_id5948502795605553414.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/6175580/img_id5948502795605553414.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/933699/img_id5192372397437264474.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/933699/img_id5192372397437264474.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/933699/img_id5192372397437264474.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/933699/img_id5192372397437264474.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/933699/img_id5192372397437264474.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/933699/img_id5192372397437264474.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/5272194/img_id5255411281294791835.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5272194/img_id5255411281294791835.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5272194/img_id5255411281294791835.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5272194/img_id5255411281294791835.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5272194/img_id5255411281294791835.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5272194/img_id5255411281294791835.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/1924580/img_id1212930814675431447.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/1924580/img_id1212930814675431447.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/1924580/img_id1212930814675431447.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/1924580/img_id1212930814675431447.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/1924580/img_id1212930814675431447.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/1924580/img_id1212930814675431447.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ26bi8bX/+aYtEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCK7h32wQvNDJm/oCGLTVhwQg4dzBBw==","sign":"22L+uGOwFYMg4o/PJNCy3JfNCYVpcy34JQ9ioQ6Y6+A="},"target":"model_card"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:228061358_5/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:228061358_5/content/content/toggleWishlist":{"skuId":"101526431804","productId":228061358,"offerId":"tJoN1tgnRWj8P-ww2dUdYg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ26bi8bX/+aYtEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCK7h32wQvNDJm/oCGLTVhwQg4dzBBw==","sign":"22L+uGOwFYMg4o/PJNCy3JfNCYVpcy34JQ9ioQ6Y6+A="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:228061358_5/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Монтелукаст-ВЕРТЕКС таб. п/о плен., 10 мг, 30 шт.

    Цена 903 ₽
  • Глемонт таб. жев., 5 мг, 28 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1436721451_6/content/content/toggleWishlist":{"skuId":"453473056","productId":1436721451,"offerId":"ryfnL0oy_8ju0-2gBDhceQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ26bi8bX/+aYtEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCKvCiq0FEKDmndgBGP3c0Acg4dzBBw==","sign":"8lGEq5uJZFEvnc4dubHj7SYHwuzM+qpmf1pFOeWbdlw="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1436721451_6/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Глемонт таб. жев., 5 мг, 28 шт.

    Цена 1 241 ₽
  • Монтелар таб. п/о плен., 10 мг, 28 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1436721452_7/content/content/gallery":{"title":"Монтелар таб. п/о плен., 10 мг, 28 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/1539743/img_id8005263717567369194.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/1539743/img_id8005263717567369194.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/1539743/img_id8005263717567369194.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/1539743/img_id8005263717567369194.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/1539743/img_id8005263717567369194.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/1539743/img_id8005263717567369194.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4399094/img_id8160030810157716302.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4399094/img_id8160030810157716302.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4399094/img_id8160030810157716302.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4399094/img_id8160030810157716302.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4399094/img_id8160030810157716302.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4399094/img_id8160030810157716302.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/5347553/img_id2660141825646226480.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5347553/img_id2660141825646226480.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5347553/img_id2660141825646226480.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5347553/img_id2660141825646226480.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5347553/img_id2660141825646226480.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5347553/img_id2660141825646226480.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ26bi8bX/+aYtEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCKzCiq0FEKXundgBGMSc0Acg4dzBBw==","sign":"OEtLkdJrbfGY2NI4MBEUHcRpkMF+2RqVClh/Jm8Hrxs="},"target":"model_card"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1436721452_7/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1436721452_7/content/content/toggleWishlist":{"skuId":"453474085","productId":1436721452,"offerId":"8wYvrgOo0FPpZyZPJiR0Jw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ26bi8bX/+aYtEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCKzCiq0FEKXundgBGMSc0Acg4dzBBw==","sign":"OEtLkdJrbfGY2NI4MBEUHcRpkMF+2RqVClh/Jm8Hrxs="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1436721452_7/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Монтелар таб. п/о плен., 10 мг, 28 шт.

    Цена 1 099 ₽
  • Реклама
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  • Таблетница на 7 дней/контейнер для таблеток и витаминов на 7 дней, Immunit
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    Таблетница на 7 дней/контейнер для таблеток и витаминов на 7 дней, Immunit

    Цена 149 ₽ вместо 189
  • Респисальф капс. с пор. д/инг., 50 мкг+500 мкг/доза, 60 шт.
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    Респисальф капс. с пор. д/инг., 50 мкг+500 мкг/доза, 60 шт.

    Цена 1 692 ₽
  • Кленил УДВ сусп. д/инг. дозир. доз, 800 мкг/2 мл, 20 шт.
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    Кленил УДВ сусп. д/инг. дозир. доз, 800 мкг/2 мл, 20 шт.

    Цена 894 ₽
  • Эуфиллин таб., 150 мг, 30 шт.
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    Эуфиллин таб., 150 мг, 30 шт.

    Цена 29 ₽
  • Сибри Бризхалер капс. с пор. д/инг. с устр. д/ингаляций (бризхалер), 50 мкг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778174463_13/content/content/gallery":{"title":"Сибри Бризхалер капс. с пор. д/инг. с устр. д/ингаляций (бризхалер), 50 мкг, 30 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/5219690/img_id2332163919604089189.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5219690/img_id2332163919604089189.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5219690/img_id2332163919604089189.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5219690/img_id2332163919604089189.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5219690/img_id2332163919604089189.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5219690/img_id2332163919604089189.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/1331400/img_id3968882601539973043.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/1331400/img_id3968882601539973043.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/1331400/img_id3968882601539973043.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/1331400/img_id3968882601539973043.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/1331400/img_id3968882601539973043.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/1331400/img_id3968882601539973043.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ26bi8bX/+aYtEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIVCP+T888GEJD29VgYkNWhBSDh3MEH","sign":"3CS66ev3kt60mYhxSsnuo26XUaSJD/fOfeBlCV/ufSY="},"target":"model_card"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778174463_13/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
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    Сибри Бризхалер капс. с пор. д/инг. с устр. д/ингаляций (бризхалер), 50 мкг, 30 шт.

    Цена 1 988 ₽
  • Таблетница на 7 дней Органайзер для лекарств
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    Таблетница на 7 дней Органайзер для лекарств

    Цена 273 ₽ вместо 279
  • Треледжи Эллипта пор д/инг. доз., 22 мкг+55 мкг+92 мкг/доза, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:835488048_15/content/content/gallery":{"title":"Треледжи Эллипта пор д/инг. доз., 22 мкг+55 мкг+92 мкг/доза, 30 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/4343092/img_id2845327046426756984.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4343092/img_id2845327046426756984.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4343092/img_id2845327046426756984.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4343092/img_id2845327046426756984.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4343092/img_id2845327046426756984.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4343092/img_id2845327046426756984.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4408567/img_id2278063781926097491.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4408567/img_id2278063781926097491.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4408567/img_id2278063781926097491.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4408567/img_id2278063781926097491.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4408567/img_id2278063781926097491.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4408567/img_id2278063781926097491.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ26bi8bX/+aYtEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIXCLCSso4DELbFssT6AhjHxp4IIOHcwQc=","sign":"WFAP+IIl5b/sDEbbWAafCXBRaLisX8kBCWMEpwo/e+g="},"target":"model_card"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:835488048_15/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
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    Треледжи Эллипта пор д/инг. доз., 22 мкг+55 мкг+92 мкг/доза, 30 шт.

    Цена 4 624 ₽
  • Алмонт таб. п/о плен., 10 мг, 28 шт.
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    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1436721426_16/content/content/toggleWishlist":{"skuId":"186989670","productId":1436721426,"offerId":"j5Slf24S8vtziLma3NDCUw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ26bi8bX/+aYtEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIVCJLCiq0FEOb4lFkYxq6MESDh3MEH","sign":"9BB1VRULpzggRoXYtj2QrNdHU3x8/fZ4eISrhoBTazA="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1436721426_16/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Алмонт таб. п/о плен., 10 мг, 28 шт.

    Цена 1 349 ₽
  • Таблетница компактная /органайзер аптечка/ контейнер для таблеток БАД Panda_Home (синего цвета)
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    Таблетница компактная /органайзер аптечка/ контейнер для таблеток БАД Panda_Home (синего цвета)

    Цена 245 ₽ вместо 263
  • Таблетница пенал - органайзер ABORNS на неделю 7 ячеек 7 дней
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    Таблетница пенал - органайзер ABORNS на неделю 7 ячеек 7 дней

    Цена 166 ₽ вместо 400
  • Контейнер для хранения/таблетница/кейс для таблеток
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    Контейнер для хранения/таблетница/кейс для таблеток

    Цена 372 ₽ вместо 699
  • Таблетница - брелок на день, 1 раздел, контейнер для таблеток металлический маленький (черный матовый)
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    Таблетница - брелок на день, 1 раздел, контейнер для таблеток металлический маленький (черный матовый)

    Цена 245 ₽ вместо 599
  • Реклама
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  • Таблетница органайзер на неделю утро / день / вечер; Органайзер для таблеток на 7 дней; Карманная аптечка
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    Таблетница органайзер на неделю утро / день / вечер; Органайзер для таблеток на 7 дней; Карманная аптечка

    Цена 684 ₽ вместо 1 890
  • Таблетница пенал - органайзер ABORNS на неделю 7 ячеек 7 дней
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    Таблетница пенал - органайзер ABORNS на неделю 7 ячеек 7 дней

    Цена 202 ₽ вместо 350
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