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Описание

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Нимесулид гран. д/приг. сусп. д/вн. приема, 100 мг, 2 г, 30 шт.

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4.8
(82)
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Количество штук в упаковке, шт.: 30

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Коротко о товаре

Артикул Маркета
419786771
Тип препарата
Назначение
Действующее вещество
Возраст
от 12 лет
Инструкция
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Нимесулид рекомендуется для терапии в качестве препарата второй линии."},{"name":"Противопоказания","value":"- Повышенная чувствительность к нимесулиду или другим компонентам препарата;\u003Cbr\u003E- Полное или неполное сочетание бронхиальной астмы, рецидивирующего полипоза носа, околоносовых пазух и непереносимость ацетилсалициловой кислоты и других НПВП (в т.ч. в анамнезе);\u003Cbr\u003E- Гепатотоксические реакции на нимесулид в анамнезе;\u003Cbr\u003E- Одновременное применение с другими лекарственными препаратами с потенциальной гепатотоксичностью (например, другими НПВП);\u003Cbr\u003E- Хронические воспалительные заболевания кишечника (болезнь Крона, язвенный колит) в фазе обострения;\u003Cbr\u003E- Период после аортокоронарного шунтирования;\u003Cbr\u003E- Лихорадочный синдром при простуде и острых респираторно-вирусных инфекциях;\u003Cbr\u003E- Подозрение на острую хирургическую патологию;\u003Cbr\u003E- Язвенная болезнь желудка или двенадцатиперстной кишки в фазе обострения;\u003Cbr\u003E- Эрозивно-язвенное поражение желудочно-кишечного тракта в фазе обострения;\u003Cbr\u003E- Эрозивно-язвенное поражение желудочно-кишечного тракта в анамнезе;\u003Cbr\u003E- Перфорации или желудочно-кишечные кровотечения в анамнезе, в том числе связанные с предшествующей терапией НПВП;\u003Cbr\u003E- Цереброваскулярные кровотечения в анамнезе, другие активные кровотечения или заболевания, сопровождающиеся повышенной кровоточивостью;\u003Cbr\u003E- Тяжелые нарушения свертывания крови;\u003Cbr\u003E- Тяжелая сердечная недостаточность;\u003Cbr\u003E- Тяжелая почечная недостаточность (клиренс креатинина менее 30 мл/мин);\u003Cbr\u003E- Прогрессирующее заболевание почек;\u003Cbr\u003E- Подтвержденная гиперкалиемия;\u003Cbr\u003E- Печеночная недостаточность, активное заболевание печени;\u003Cbr\u003E- Детский возраст до 12 лет;\u003Cbr\u003E- Беременность и период грудного вскармливания;\u003Cbr\u003E- Алкоголизм, наркотическая зависимость, дефицит сахаразы/изомальтазы, непереносимость фруктозы, глюкозо-галактозная мальабсорбция, так как препарат содержит сахарозу."},{"name":"Состав","value":"Состав на один пакет:\u003Cbr\u003EДействующее вещество: нимесулид (в пересчете на 100 % вещество) - 100,0 мг;\u003Cbr\u003EВспомогательные вещества: ароматизатор апельсиновый - 42,0 мг, лимонная кислота - 30,0 мг, мальтодекстрин - 15,0 мг, макрогола цетостеарат - 8,0 мг, сахароза - до массы 2000,0 мг."},{"name":"Действующее вещество","value":"Нимесулид","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["27144131:28709561"]}}},{"name":"Способ применения и дозы","value":"Внутрь. Взрослым и детям старше 12 лет внутрь (масса тела более 40 кг) назначают по 100 мг 2 раза в день. Принимают после еды с достаточным количеством воды. Максимальная суточная доза для взрослых и детей старше 12 лет составляет 200 мг.\u003Cbr\u003EПациенты пожилого возраста: при терапии пожилых пациентов коррекция суточной дозы не требуется.\u003Cbr\u003EПациенты с почечной недостаточностью: у пациентов с почечной недостаточностью легкой и умеренной степени тяжести (клиренс креатинина 30-60 мл/мин) коррекция дозы не требуется, пациентам с тяжелой почечной недостаточностью (клиренс креатинина меньше 30 мл/мин) нимесулид противопоказан.\u003Cbr\u003EПациенты с печеночной недостаточностью: применение нимесулида у пациентов с печеночной недостаточностью противопоказано.\u003Cbr\u003EКурс лечения: по назначению врача. Для уменьшения вероятности развития побочных эффектов рекомендуется принимать минимальную эффективную дозу в течение минимально короткого времени. Максимальная продолжительность курса лечения нимесулидом - 15 дней."},{"name":"Побочные действия","value":"Частота побочных эффектов классифицируется в зависимости от частоты встречаемости случая: очень часто (\u003E1/10), часто (от ≥1/100 до \u003C 1/10), нечасто (от ≥1/1000 до \u003C 1/100), редко (от ≥1/10000 до \u003C 1/1000), очень редко (от ≥1/10000), частота неизвестна (частота не может быть подсчитана по доступным данным).\u003Cbr\u003EНарушения со стороны крови и лимфатической системы: редко - анемия, эозинофилия, геморрагии; очень редко - тромбоцитопения, панцитопения, пурпура тромбоцитопеническая, удлинение времени кровотечения.\u003Cbr\u003EНарушения со стороны иммунной системы: редко - реакции гиперчувствительности; очень редко - анафилактоидные реакции.\u003Cbr\u003EНарушения психики: редко - чувство страха, нервозность, ночные «кошмарные» сновидения.\u003Cbr\u003EНарушения со стороны нервной системы: нечасто - головокружение; очень редко - головная боль, сонливость, энцефалопатия (синдром Рейе).\u003Cbr\u003EНарушения со стороны органа зрения: редко - нечеткость зрения; очень редко - нарушение зрения.\u003Cbr\u003EНарушения со стороны органа слуха и лабиринтные нарушения: очень редко - вертиго.\u003Cbr\u003EНарушения со стороны сердца: редко - тахикардия, ощущение сердцебиения.\u003Cbr\u003EНарушения со стороны сосудов: нечасто повышение артериального давления; редко лабильность артериального давления, «приливы» крови к коже лица.\u003Cbr\u003EНарушения со стороны дыхательной системы, органов грудной клетки и средостения: нечасто - одышка; очень редко - обострение бронхиальной астмы, бронхоспазм.\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта: часто - диарея, тошнота, рвота; нечасто - запор, метеоризм, гастрит, желудочно-кишечное кровотечение, язва и/или перфорация желудка или двенадцатиперстной кишки; очень редко - боли в животе, диспепсия, стоматит, дегтеобразный стул.\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей: часто - повышение активности «печеночных» ферментов; очень редко - гепатит, молниеносный (фульминантный) гепатит (включая летальные исходы), желтуха, холестаз.\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей: нечасто - зуд, кожная сыпь, повышенная потливость; редко - эритема, дерматит; очень редко - крапивница, ангионевротический отек, отек лица, многоформная эритема, синдром Стивенса-Джонсона, токсический эпидермальный некролиз (синдром Лайелла).\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей: редко - дизурия, гематурия, задержка мочеиспускания; очень редко - почечная недостаточность, олигурия, интерстициальный нефрит, гиперкалиемия.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения: нечасто - периферические отеки; редко - недомогание, астения; очень редко - гипотермия."},{"name":"Фармакологическое действие","value":"Нимесулид является нестероидным противовоспалительным средством из класса сульфонамидов. Оказывает противовоспалительное, обезболивающее и жаропонижающее действие. В отличие от неселективных НПВП, нимесулид главным образом ингибирует циклооксигеназу-2 (ЦОГ-2), тормозит синтез простагландинов в очаге воспаления; оказывает менее выраженное угнетающее воздействие на циклооксигеназу-1 (ЦОГ- 1)."},{"name":"Фармакологическая группа","value":"нестероидный противовоспалительный препарат (НПВП)"},{"name":"Форма выпуска","value":"гранулы"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 12 лет"},{"name":"Условия хранения","value":"При температуре не выше 25 0С.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы: апатия, сонливость, тошнота, рвота, боль в эпигастральной области. Эти симптомы обычно обратимы при проведении симптоматической и поддерживающей терапии. Возможно повышение артериального давления, возникновение желудочно-кишечного кровотечения, острой почечной недостаточности, угнетение дыхания, кома, анафилактоидные реакции.\u003Cbr\u003EЛечение: Симптоматическая и поддерживающая терапия. Специфического антидота нет. В случае, если симптомы передозировки возникли в течение 4-х часов после приема препарата, необходимо вызвать рвоту, и/или обеспечить прием активированного угля (от 60 до 100 г для взрослого человека) и/или осмотического слабительного средства. Форсированный диурез, гемодиализ, гемоперфузия, защелачивание мочи неэффективны из-за высокой степени связывания нимесулида с белками плазмы крови (до 97,5 %). Необходим контроль за состоянием функции почек и печени."},{"name":"Применение при беременности и кормлении грудью","value":"Беременность\u003Cbr\u003EКак и другие препараты из класса НПВП, которые ингибируют синтез простагландинов, нимесулид может отрицательно влиять на течение беременности и/или на развитие эмбриона и может приводить к преждевременному закрытию артериального протока, гипертензии в системе легочной артерии плода, нарушению функции почек, которое может переходить в почечную недостаточность с олигурией у плода, к повышению риска кровотечений, снижению контрактильности матки, возникновению периферических отеков у матери.\u003Cbr\u003EПрименение нимесулида в период беременности противопоказано.\u003Cbr\u003EПериод грудного вскармливания\u003Cbr\u003EПрименение нимесулида в период грудного вскармливани противопоказано.\u003Cbr\u003EФертильность:\u003Cbr\u003EПрименение препарата может отрицательно влиять на женскую фертильность и не рекомендуется женщинам, планирующим беременность."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Влияние нимесулида на способность к управлению транспортными средствами и механизмами не изучалось, однако, учитывая нежелательные реакции со стороны нервной системы (головокружение, сонливость), следует воздержаться от управления автотранспортными средствами и другими механизмами."},{"name":"Особые указания","value":"Нежелательные побочные эффекты можно свести к минимуму при применении препарата в минимальной эффективной дозе при минимальной длительности применения, необходимой для купирования болевого синдрома.\u003Cbr\u003EИмеются данные об очень редких случаях серьезных реакций со стороны печени, в том числе, случаях летального исхода, связанных с применением нимесулидсодержащих препаратов. При появлении симптомов, схожих с признаками поражения печени (анорексия, кожный зуд, пожелтение кожных покровов, тошнота, рвота, боли в животе, потемнение мочи, повышение активности \"печеночных\" трансаминаз) следует немедленно прекратить применение нимесулида и обратиться к врачу. Повторное применение нимесулида у таких пациентов противопоказано. После 2-х недель применения препарата необходим контроль показателей функции печени (\"трансаминазы\"). Сообщается о реакциях со стороны печени, имеющих в большинстве случаев обратимый характер, при кратковременном применении препарата. Во время применения нимесулида пациент должен воздерживаться от приема других анальгетиков, включая НПВП (в т.ч. селективные-ингибиторы ЦОГ-2).\u003Cbr\u003EНимесулид следует применять с осторожностью у пациентов с желудочно-кишечными заболеваниями в анамнезе (язвенный колит, болезнь Крона), поскольку возможно обострение этих заболеваний.\u003Cbr\u003EРиск возникновения желудочно-кишечного кровотечения, пептической язвы/перфорации желудка или двенадцатиперстной кишки повышается у пациентов с наличием язвенного поражения ЖКТ (язвенный колит, болезнь Крона) в анамнезе, а также у пожилых пациентов, с увеличением дозы НПВП, поэтому лечение следует начинать с наименьшей возможной дозы. Таким пациентам, а также пациентам, которым требуется одновременное применение низких доз ацетилсалициловой кислоты или других средств, повышающих риск возникновения осложнений со стороны желудочно-кишечного тракта, рекомендуется дополнительно назначать прием гастропротекторов (мизопростол или блокаторы протонной помпы). Пациенты с заболеваниями ЖКТ в анамнезе, в особенности пожилые пациенты, должны сообщать врачу о вновь возникших симптомах со стороны ЖКТ (особенно о симптомах, которые могут свидетельствовать о возможном желудочно-кишечном кровотечении).\u003Cbr\u003EНимесулид следует назначать с осторожностью пациентам, принимающим препараты, увеличивающие риск изъязвления или кровотечения (пероральные кортикостероиды, антикоагулянты, например варфарин, селективные ингибиторы обратного захвата серотонина или антитромбоцитарные агенты, например, ацетилсалициловая кислота). В случае возникновения желудочно-кишечного кровотечения или язвенного поражения ЖКТ у пациентов, принимающих нимесулид, лечение препаратом необходимо немедленно прекратить.\u003Cbr\u003EУчитывая сообщения о нарушениях зрения у пациентов, принимающих другие НПВП, при появлении любого нарушения зрения применение нимесулида должно быть немедленно прекращено и проведено офтальмологическое обследование.\u003Cbr\u003EПрепарат может вызвать задержку жидкости в тканях, поэтому пациентам с артериальной гипертензией, с почечной и/или сердечной недостаточностью, ишемической болезнью сердца, заболеванием периферических артерий и/или цереброваскулярными заболеваниями, с наличием факторов риска развития сердечно-сосудистых заболеваний (например: гиперлипидемией, сахарным диабетом, у курящих) нимесулид следует применять с особой осторожностью. В случае ухудшения состояния, лечение нимесулидом необходимо прекратить.\u003Cbr\u003EКлинические исследования и эпидемиологические данные позволяют сделать вывод о том, что НПВП, особенно в высоких дозах и при длительном применении, могут приводить к незначительному увеличению риска возникновения инфаркта миокарда или инсульта. Для исключения риска возникновения таких событий применении нимесулида данных недостаточно.\u003Cbr\u003EПри возникновении признаков \"простуды\" или острой респираторно-вирусной инфекции в процессе применения нимесулида прием препарата должен быть прекращен.\u003Cbr\u003EНимесулид может изменять свойства тромбоцитов, поэтому необходимо соблюдать осторожность при применении препарата у лиц с геморрагическим диатезом, однако препарат не заменяет профилактического действия ацетилсалициловой кислоты при сердечно-сосудистых заболеваниях.\u003Cbr\u003EПожилые пациенты особенно подвержены неблагоприятным реакциям на НПВП, в том числе, риску возникновения желудочно-кишечных кровотечений и перфораций, угрожающих жизни пациента, снижению функций почек, печени и сердца. При приеме нимесулида для данной категории пациентов необходим надлежащий клинический контроль. Имеются данные о возникновении в редких случаях кожных реакций (таких как эксфолиативный дерматит, синдром Стивенса-Джонсона, токсический эпидермальный некролиз) при приеме НПВП, в том числе и нимесулида. При первых проявлениях кожной сыпи, поражении слизистых оболочек или других признаках аллергической реакции прием нимесулида следует немедленно прекратить.\u003Cbr\u003EС осторожностью:\u003Cbr\u003E- Артериальная гипертензия;\u003Cbr\u003E- Ишемическая болезнь сердца;\u003Cbr\u003E- Цереброваскулярные заболевания;\u003Cbr\u003E- Тяжелая сердечная недостаточность;\u003Cbr\u003E- Дислипидемия/гиперлипидемия;\u003Cbr\u003E- Сахарный диабет;\u003Cbr\u003E- Заболевания периферических артерий;\u003Cbr\u003E- Геморрагический диатез;\u003Cbr\u003E- Курение;\u003Cbr\u003E- Почечная недостаточность (клиренс креатинина 30-60 мл/мин);\u003Cbr\u003E- Анамнестические данные о развитии эрозивно-язвенного поражения ЖКТ, наличие инфекции Helicobacter pylori;\u003Cbr\u003E- Пожилой возраст;\u003Cbr\u003E- Длительное применение нестероидных противовоспалительных препаратов;\u003Cbr\u003E- Частое употребление алкоголя, тяжелые соматические заболевания, системная красная волчанка (СКВ) и другие системные заболевания соединительной ткани;\u003Cbr\u003E- Сопутствующая терапия следующими препаратами: антикоагулянты (например, варфарин), антиагреганты (например, ацетилсалициловая кислота, клопидогрел), пероральные глюкокортикостероиды (например, преднизолон), селективные ингибиторы обратного захвата серотонина (например, циталопрам, флуоксетин, пароксетин, сертралин)."},{"name":"Взаимодействие","value":"Глюкокортикостероиды повышают риск возникновения желудочно-кишечного тракта или кровотечения.\u003Cbr\u003EАнтитромбоцитарные средства и селективные ингибиторы повторного поглощения серотонина (SSRIs), например, флуоксетин, увеличивают риск возникновения желудочно-кишечного кровотечения.\u003Cbr\u003EАнтикоагулянты. НПВП могут усиливать действие антикоагулянтов, таких как варфарин, или препаратов, обладающих антитромбоцитарным действием, таких как ацетилсалициловая кислота. Из-за повышенного риска кровотечений, такая комбинация не рекомендуется и противопоказана пациентам с тяжелыми нарушениями коагуляции. Если комбинированной терапии все же нельзя избежать, необходимо проводить тщательный контроль показателей свертываемости крови.\u003Cbr\u003EДругие нестероидные противовоспалительные препараты (НПВП): Одновременное применение нимесулид-содержащих препаратов с другими НПВП, включая ацетилсалициловую кислоту в разовой дозе более 1 г или в суточной дозе более 3 г, не рекомендуется.\u003Cbr\u003EДиуретики. НПВП могут снижать действие диуретиков. У здоровых добровольцев нимесулид временно снижает выведение натрия под действием фуросемида, в меньшей степени - выведение калия и снижает собственно диуретический эффект. Одновременное применение нимесулида и фуросемида приводит к уменьшению (приблизительно на 20 %) площади под кривой \"концентрация время\" (AUC) и снижению кумулятивной экскреции фуросемида без изменения почечного клиренса фуросемида. Одновременное применение фуросемида и нимесулида требует осторожности у пациентов с почечной или сердечной недостаточностью.\u003Cbr\u003EИнгибиторы АПФ и антагонисты рецепторов ангиотензина-II. НПВП могут снижать действие гипотензивных препаратов. У пациентов с почечной недостаточностью легкой и умеренной степени (клиренс креатинина 30-60 мл/мин) при одновременном применении ингибиторов АПФ, антагонистов рецепторов ангиотензина II и средств, подавляющих систему циклооксигеназы (НПВП, антиагреганты), возможно дальнейшее ухудшение функции почек и возникновение острой почечной недостаточности, которая, как правило, бывает обратимой. Эти взаимодействия следует учитывать у пациентов, принимающих нимесулид в сочетании с ингибиторами АПФ или антагонистами рецепторов ангиотензина П. Поэтому одновременное применение этих препаратов следует осуществлять с осторожностью, особенно у пожилых пациентов. Пациенты должны получать достаточное количество жидкости, а почечную функцию следует тщательно контролировать после начала одновременного применения.\u003Cbr\u003EМифепристон. В связи с теоретическим риском изменения эффективности мифепристона под влиянием ингибиторов синтеза простагландинов, НПВП не следует применять ранее, чем через 8-12 сут после отмены мифепристона.\u003Cbr\u003EИмеются данные о том, что НПВП уменьшают клиренс лития, что приводит к повышению концентрации лития в плазме крови и его токсичности. При применении нимесулида у пациентов, находящихся на терапии препаратами лития, следует осуществлять регулярный контроль концентрации лития в плазме крови.\u003Cbr\u003EКлинически значимых взаимодействий с глибенкламидом, теофиллином, дигоксином, циметидином и антацидными препаратами (например, комбинация алюминия и магния гидроксидов) не наблюдалось.\u003Cbr\u003EНимесулид подавляет активность изофермента СYР2С9. При одновременном применении с нимесулидом препаратов, являющихся субстратами этого фермента, концентрация последних в плазме может повышаться.\u003Cbr\u003EПри назначении нимесулида менее чем за 24 часа до или после приема метотрексата требуется соблюдать осторожность, так как в таких случаях уровень метотрексата в плазме крови и, соответственно, токсические эффекты могут повышаться.\u003Cbr\u003EВ связи с действием на почечные простагландины, ингибиторы синтетаз простагландинов, к каким относится нимесулид, могут повышать нефротоксичность циклоспоринов. Исследования in vitro показали, что нимесулид вытесняется из мест связывания толбутамидом, салициловой кислотой и вальпроевой кислотой. Несмотря на то, что данные взаимодействия были определены в плазме крови, указанные эффекты не наблюдались в процессе клинического применения препарата."},{"name":"Регистрационный номер","value":"ЛП-006772"},{"name":"Дата государственной регистрации","value":"11.02.2021"},{"name":"Владелец регистрационного удостоверения","value":"Усолье-Сибирский химфармзавод","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["34324371:35649313","7893318:16003123"]}}},{"name":"Изготовитель","value":"Усолье-Сибирский химфармзавод"},{"name":"Фасовщик","value":"Усолье-Сибирский химфармзавод"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Нимесулид","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["17796364:17951854"]}}},{"name":"Срок годности","value":"1 г."}]}},"fullSpecsGrouped":{"7794722592141567373":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"опорно-двигательная система"},{"name":"Назначение","value":"альгодисменорея, зубная боль, остеоартрит, остеоартроз, хронический болевой синдром скелетно-мышечной системы"},{"name":"Показания к применению","value":"Терапия острой боли:\u003Cbr\u003E- боль в нижней части спины и/или области поясницы;\u003Cbr\u003E- болевой синдром, связанный с заболеваниями опорно-двигательного аппарата, в том числе тендиниты, бурситы;\u003Cbr\u003E- боль при ушибах, растяжениях связок и вывихах суставов;\u003Cbr\u003E- зубная боль;\u003Cbr\u003E- симптоматическое лечение остеоартроза (остеоартрита) с болевым синдромом;\u003Cbr\u003E- первичная альгодисменорея.\u003Cbr\u003E Препарат предназначен для симптоматической терапии, уменьшения боли и воспаления на момент использования, на прогрессирование заболевания не влияет. Нимесулид рекомендуется для терапии в качестве препарата второй линии."},{"name":"Противопоказания","value":"- Повышенная чувствительность к нимесулиду или другим компонентам препарата;\u003Cbr\u003E- Полное или неполное сочетание бронхиальной астмы, рецидивирующего полипоза носа, околоносовых пазух и непереносимость ацетилсалициловой кислоты и других НПВП (в т.ч. в анамнезе);\u003Cbr\u003E- Гепатотоксические реакции на нимесулид в анамнезе;\u003Cbr\u003E- Одновременное применение с другими лекарственными препаратами с потенциальной гепатотоксичностью (например, другими НПВП);\u003Cbr\u003E- Хронические воспалительные заболевания кишечника (болезнь Крона, язвенный колит) в фазе обострения;\u003Cbr\u003E- Период после аортокоронарного шунтирования;\u003Cbr\u003E- Лихорадочный синдром при простуде и острых респираторно-вирусных инфекциях;\u003Cbr\u003E- Подозрение на острую хирургическую патологию;\u003Cbr\u003E- Язвенная болезнь желудка или двенадцатиперстной кишки в фазе обострения;\u003Cbr\u003E- Эрозивно-язвенное поражение желудочно-кишечного тракта в фазе обострения;\u003Cbr\u003E- Эрозивно-язвенное поражение желудочно-кишечного тракта в анамнезе;\u003Cbr\u003E- Перфорации или желудочно-кишечные кровотечения в анамнезе, в том числе связанные с предшествующей терапией НПВП;\u003Cbr\u003E- Цереброваскулярные кровотечения в анамнезе, другие активные кровотечения или заболевания, сопровождающиеся повышенной кровоточивостью;\u003Cbr\u003E- Тяжелые нарушения свертывания крови;\u003Cbr\u003E- Тяжелая сердечная недостаточность;\u003Cbr\u003E- Тяжелая почечная недостаточность (клиренс креатинина менее 30 мл/мин);\u003Cbr\u003E- Прогрессирующее заболевание почек;\u003Cbr\u003E- Подтвержденная гиперкалиемия;\u003Cbr\u003E- Печеночная недостаточность, активное заболевание печени;\u003Cbr\u003E- Детский возраст до 12 лет;\u003Cbr\u003E- Беременность и период грудного вскармливания;\u003Cbr\u003E- Алкоголизм, наркотическая зависимость, дефицит сахаразы/изомальтазы, непереносимость фруктозы, глюкозо-галактозная мальабсорбция, так как препарат содержит сахарозу."},{"name":"Состав","value":"Состав на один пакет:\u003Cbr\u003EДействующее вещество: нимесулид (в пересчете на 100 % вещество) - 100,0 мг;\u003Cbr\u003EВспомогательные вещества: ароматизатор апельсиновый - 42,0 мг, лимонная кислота - 30,0 мг, мальтодекстрин - 15,0 мг, макрогола цетостеарат - 8,0 мг, сахароза - до массы 2000,0 мг."},{"name":"Действующее вещество","value":"Нимесулид"},{"name":"Способ применения и дозы","value":"Внутрь. Взрослым и детям старше 12 лет внутрь (масса тела более 40 кг) назначают по 100 мг 2 раза в день. Принимают после еды с достаточным количеством воды. Максимальная суточная доза для взрослых и детей старше 12 лет составляет 200 мг.\u003Cbr\u003EПациенты пожилого возраста: при терапии пожилых пациентов коррекция суточной дозы не требуется.\u003Cbr\u003EПациенты с почечной недостаточностью: у пациентов с почечной недостаточностью легкой и умеренной степени тяжести (клиренс креатинина 30-60 мл/мин) коррекция дозы не требуется, пациентам с тяжелой почечной недостаточностью (клиренс креатинина меньше 30 мл/мин) нимесулид противопоказан.\u003Cbr\u003EПациенты с печеночной недостаточностью: применение нимесулида у пациентов с печеночной недостаточностью противопоказано.\u003Cbr\u003EКурс лечения: по назначению врача. Для уменьшения вероятности развития побочных эффектов рекомендуется принимать минимальную эффективную дозу в течение минимально короткого времени. Максимальная продолжительность курса лечения нимесулидом - 15 дней."},{"name":"Побочные действия","value":"Частота побочных эффектов классифицируется в зависимости от частоты встречаемости случая: очень часто (\u003E1/10), часто (от ≥1/100 до \u003C 1/10), нечасто (от ≥1/1000 до \u003C 1/100), редко (от ≥1/10000 до \u003C 1/1000), очень редко (от ≥1/10000), частота неизвестна (частота не может быть подсчитана по доступным данным).\u003Cbr\u003EНарушения со стороны крови и лимфатической системы: редко - анемия, эозинофилия, геморрагии; очень редко - тромбоцитопения, панцитопения, пурпура тромбоцитопеническая, удлинение времени кровотечения.\u003Cbr\u003EНарушения со стороны иммунной системы: редко - реакции гиперчувствительности; очень редко - анафилактоидные реакции.\u003Cbr\u003EНарушения психики: редко - чувство страха, нервозность, ночные «кошмарные» сновидения.\u003Cbr\u003EНарушения со стороны нервной системы: нечасто - головокружение; очень редко - головная боль, сонливость, энцефалопатия (синдром Рейе).\u003Cbr\u003EНарушения со стороны органа зрения: редко - нечеткость зрения; очень редко - нарушение зрения.\u003Cbr\u003EНарушения со стороны органа слуха и лабиринтные нарушения: очень редко - вертиго.\u003Cbr\u003EНарушения со стороны сердца: редко - тахикардия, ощущение сердцебиения.\u003Cbr\u003EНарушения со стороны сосудов: нечасто повышение артериального давления; редко лабильность артериального давления, «приливы» крови к коже лица.\u003Cbr\u003EНарушения со стороны дыхательной системы, органов грудной клетки и средостения: нечасто - одышка; очень редко - обострение бронхиальной астмы, бронхоспазм.\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта: часто - диарея, тошнота, рвота; нечасто - запор, метеоризм, гастрит, желудочно-кишечное кровотечение, язва и/или перфорация желудка или двенадцатиперстной кишки; очень редко - боли в животе, диспепсия, стоматит, дегтеобразный стул.\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей: часто - повышение активности «печеночных» ферментов; очень редко - гепатит, молниеносный (фульминантный) гепатит (включая летальные исходы), желтуха, холестаз.\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей: нечасто - зуд, кожная сыпь, повышенная потливость; редко - эритема, дерматит; очень редко - крапивница, ангионевротический отек, отек лица, многоформная эритема, синдром Стивенса-Джонсона, токсический эпидермальный некролиз (синдром Лайелла).\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей: редко - дизурия, гематурия, задержка мочеиспускания; очень редко - почечная недостаточность, олигурия, интерстициальный нефрит, гиперкалиемия.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения: нечасто - периферические отеки; редко - недомогание, астения; очень редко - гипотермия."},{"name":"Фармакологическое действие","value":"Нимесулид является нестероидным противовоспалительным средством из класса сульфонамидов. Оказывает противовоспалительное, обезболивающее и жаропонижающее действие. В отличие от неселективных НПВП, нимесулид главным образом ингибирует циклооксигеназу-2 (ЦОГ-2), тормозит синтез простагландинов в очаге воспаления; оказывает менее выраженное угнетающее воздействие на циклооксигеназу-1 (ЦОГ- 1)."},{"name":"Фармакологическая группа","value":"нестероидный противовоспалительный препарат (НПВП)"},{"name":"Форма выпуска","value":"гранулы"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 12 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"При температуре не выше 25 0С.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы: апатия, сонливость, тошнота, рвота, боль в эпигастральной области. Эти симптомы обычно обратимы при проведении симптоматической и поддерживающей терапии. Возможно повышение артериального давления, возникновение желудочно-кишечного кровотечения, острой почечной недостаточности, угнетение дыхания, кома, анафилактоидные реакции.\u003Cbr\u003EЛечение: Симптоматическая и поддерживающая терапия. Специфического антидота нет. В случае, если симптомы передозировки возникли в течение 4-х часов после приема препарата, необходимо вызвать рвоту, и/или обеспечить прием активированного угля (от 60 до 100 г для взрослого человека) и/или осмотического слабительного средства. Форсированный диурез, гемодиализ, гемоперфузия, защелачивание мочи неэффективны из-за высокой степени связывания нимесулида с белками плазмы крови (до 97,5 %). Необходим контроль за состоянием функции почек и печени."},{"name":"Применение при беременности и кормлении грудью","value":"Беременность\u003Cbr\u003EКак и другие препараты из класса НПВП, которые ингибируют синтез простагландинов, нимесулид может отрицательно влиять на течение беременности и/или на развитие эмбриона и может приводить к преждевременному закрытию артериального протока, гипертензии в системе легочной артерии плода, нарушению функции почек, которое может переходить в почечную недостаточность с олигурией у плода, к повышению риска кровотечений, снижению контрактильности матки, возникновению периферических отеков у матери.\u003Cbr\u003EПрименение нимесулида в период беременности противопоказано.\u003Cbr\u003EПериод грудного вскармливания\u003Cbr\u003EПрименение нимесулида в период грудного вскармливани противопоказано.\u003Cbr\u003EФертильность:\u003Cbr\u003EПрименение препарата может отрицательно влиять на женскую фертильность и не рекомендуется женщинам, планирующим беременность."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Влияние нимесулида на способность к управлению транспортными средствами и механизмами не изучалось, однако, учитывая нежелательные реакции со стороны нервной системы (головокружение, сонливость), следует воздержаться от управления автотранспортными средствами и другими механизмами."},{"name":"Особые указания","value":"Нежелательные побочные эффекты можно свести к минимуму при применении препарата в минимальной эффективной дозе при минимальной длительности применения, необходимой для купирования болевого синдрома.\u003Cbr\u003EИмеются данные об очень редких случаях серьезных реакций со стороны печени, в том числе, случаях летального исхода, связанных с применением нимесулидсодержащих препаратов. При появлении симптомов, схожих с признаками поражения печени (анорексия, кожный зуд, пожелтение кожных покровов, тошнота, рвота, боли в животе, потемнение мочи, повышение активности \"печеночных\" трансаминаз) следует немедленно прекратить применение нимесулида и обратиться к врачу. Повторное применение нимесулида у таких пациентов противопоказано. После 2-х недель применения препарата необходим контроль показателей функции печени (\"трансаминазы\"). Сообщается о реакциях со стороны печени, имеющих в большинстве случаев обратимый характер, при кратковременном применении препарата. Во время применения нимесулида пациент должен воздерживаться от приема других анальгетиков, включая НПВП (в т.ч. селективные-ингибиторы ЦОГ-2).\u003Cbr\u003EНимесулид следует применять с осторожностью у пациентов с желудочно-кишечными заболеваниями в анамнезе (язвенный колит, болезнь Крона), поскольку возможно обострение этих заболеваний.\u003Cbr\u003EРиск возникновения желудочно-кишечного кровотечения, пептической язвы/перфорации желудка или двенадцатиперстной кишки повышается у пациентов с наличием язвенного поражения ЖКТ (язвенный колит, болезнь Крона) в анамнезе, а также у пожилых пациентов, с увеличением дозы НПВП, поэтому лечение следует начинать с наименьшей возможной дозы. Таким пациентам, а также пациентам, которым требуется одновременное применение низких доз ацетилсалициловой кислоты или других средств, повышающих риск возникновения осложнений со стороны желудочно-кишечного тракта, рекомендуется дополнительно назначать прием гастропротекторов (мизопростол или блокаторы протонной помпы). Пациенты с заболеваниями ЖКТ в анамнезе, в особенности пожилые пациенты, должны сообщать врачу о вновь возникших симптомах со стороны ЖКТ (особенно о симптомах, которые могут свидетельствовать о возможном желудочно-кишечном кровотечении).\u003Cbr\u003EНимесулид следует назначать с осторожностью пациентам, принимающим препараты, увеличивающие риск изъязвления или кровотечения (пероральные кортикостероиды, антикоагулянты, например варфарин, селективные ингибиторы обратного захвата серотонина или антитромбоцитарные агенты, например, ацетилсалициловая кислота). В случае возникновения желудочно-кишечного кровотечения или язвенного поражения ЖКТ у пациентов, принимающих нимесулид, лечение препаратом необходимо немедленно прекратить.\u003Cbr\u003EУчитывая сообщения о нарушениях зрения у пациентов, принимающих другие НПВП, при появлении любого нарушения зрения применение нимесулида должно быть немедленно прекращено и проведено офтальмологическое обследование.\u003Cbr\u003EПрепарат может вызвать задержку жидкости в тканях, поэтому пациентам с артериальной гипертензией, с почечной и/или сердечной недостаточностью, ишемической болезнью сердца, заболеванием периферических артерий и/или цереброваскулярными заболеваниями, с наличием факторов риска развития сердечно-сосудистых заболеваний (например: гиперлипидемией, сахарным диабетом, у курящих) нимесулид следует применять с особой осторожностью. В случае ухудшения состояния, лечение нимесулидом необходимо прекратить.\u003Cbr\u003EКлинические исследования и эпидемиологические данные позволяют сделать вывод о том, что НПВП, особенно в высоких дозах и при длительном применении, могут приводить к незначительному увеличению риска возникновения инфаркта миокарда или инсульта. Для исключения риска возникновения таких событий применении нимесулида данных недостаточно.\u003Cbr\u003EПри возникновении признаков \"простуды\" или острой респираторно-вирусной инфекции в процессе применения нимесулида прием препарата должен быть прекращен.\u003Cbr\u003EНимесулид может изменять свойства тромбоцитов, поэтому необходимо соблюдать осторожность при применении препарата у лиц с геморрагическим диатезом, однако препарат не заменяет профилактического действия ацетилсалициловой кислоты при сердечно-сосудистых заболеваниях.\u003Cbr\u003EПожилые пациенты особенно подвержены неблагоприятным реакциям на НПВП, в том числе, риску возникновения желудочно-кишечных кровотечений и перфораций, угрожающих жизни пациента, снижению функций почек, печени и сердца. При приеме нимесулида для данной категории пациентов необходим надлежащий клинический контроль. Имеются данные о возникновении в редких случаях кожных реакций (таких как эксфолиативный дерматит, синдром Стивенса-Джонсона, токсический эпидермальный некролиз) при приеме НПВП, в том числе и нимесулида. При первых проявлениях кожной сыпи, поражении слизистых оболочек или других признаках аллергической реакции прием нимесулида следует немедленно прекратить.\u003Cbr\u003EС осторожностью:\u003Cbr\u003E- Артериальная гипертензия;\u003Cbr\u003E- Ишемическая болезнь сердца;\u003Cbr\u003E- Цереброваскулярные заболевания;\u003Cbr\u003E- Тяжелая сердечная недостаточность;\u003Cbr\u003E- Дислипидемия/гиперлипидемия;\u003Cbr\u003E- Сахарный диабет;\u003Cbr\u003E- Заболевания периферических артерий;\u003Cbr\u003E- Геморрагический диатез;\u003Cbr\u003E- Курение;\u003Cbr\u003E- Почечная недостаточность (клиренс креатинина 30-60 мл/мин);\u003Cbr\u003E- Анамнестические данные о развитии эрозивно-язвенного поражения ЖКТ, наличие инфекции Helicobacter pylori;\u003Cbr\u003E- Пожилой возраст;\u003Cbr\u003E- Длительное применение нестероидных противовоспалительных препаратов;\u003Cbr\u003E- Частое употребление алкоголя, тяжелые соматические заболевания, системная красная волчанка (СКВ) и другие системные заболевания соединительной ткани;\u003Cbr\u003E- Сопутствующая терапия следующими препаратами: антикоагулянты (например, варфарин), антиагреганты (например, ацетилсалициловая кислота, клопидогрел), пероральные глюкокортикостероиды (например, преднизолон), селективные ингибиторы обратного захвата серотонина (например, циталопрам, флуоксетин, пароксетин, сертралин)."},{"name":"Взаимодействие","value":"Глюкокортикостероиды повышают риск возникновения желудочно-кишечного тракта или кровотечения.\u003Cbr\u003EАнтитромбоцитарные средства и селективные ингибиторы повторного поглощения серотонина (SSRIs), например, флуоксетин, увеличивают риск возникновения желудочно-кишечного кровотечения.\u003Cbr\u003EАнтикоагулянты. НПВП могут усиливать действие антикоагулянтов, таких как варфарин, или препаратов, обладающих антитромбоцитарным действием, таких как ацетилсалициловая кислота. Из-за повышенного риска кровотечений, такая комбинация не рекомендуется и противопоказана пациентам с тяжелыми нарушениями коагуляции. Если комбинированной терапии все же нельзя избежать, необходимо проводить тщательный контроль показателей свертываемости крови.\u003Cbr\u003EДругие нестероидные противовоспалительные препараты (НПВП): Одновременное применение нимесулид-содержащих препаратов с другими НПВП, включая ацетилсалициловую кислоту в разовой дозе более 1 г или в суточной дозе более 3 г, не рекомендуется.\u003Cbr\u003EДиуретики. НПВП могут снижать действие диуретиков. У здоровых добровольцев нимесулид временно снижает выведение натрия под действием фуросемида, в меньшей степени - выведение калия и снижает собственно диуретический эффект. Одновременное применение нимесулида и фуросемида приводит к уменьшению (приблизительно на 20 %) площади под кривой \"концентрация время\" (AUC) и снижению кумулятивной экскреции фуросемида без изменения почечного клиренса фуросемида. Одновременное применение фуросемида и нимесулида требует осторожности у пациентов с почечной или сердечной недостаточностью.\u003Cbr\u003EИнгибиторы АПФ и антагонисты рецепторов ангиотензина-II. НПВП могут снижать действие гипотензивных препаратов. У пациентов с почечной недостаточностью легкой и умеренной степени (клиренс креатинина 30-60 мл/мин) при одновременном применении ингибиторов АПФ, антагонистов рецепторов ангиотензина II и средств, подавляющих систему циклооксигеназы (НПВП, антиагреганты), возможно дальнейшее ухудшение функции почек и возникновение острой почечной недостаточности, которая, как правило, бывает обратимой. Эти взаимодействия следует учитывать у пациентов, принимающих нимесулид в сочетании с ингибиторами АПФ или антагонистами рецепторов ангиотензина П. Поэтому одновременное применение этих препаратов следует осуществлять с осторожностью, особенно у пожилых пациентов. Пациенты должны получать достаточное количество жидкости, а почечную функцию следует тщательно контролировать после начала одновременного применения.\u003Cbr\u003EМифепристон. В связи с теоретическим риском изменения эффективности мифепристона под влиянием ингибиторов синтеза простагландинов, НПВП не следует применять ранее, чем через 8-12 сут после отмены мифепристона.\u003Cbr\u003EИмеются данные о том, что НПВП уменьшают клиренс лития, что приводит к повышению концентрации лития в плазме крови и его токсичности. При применении нимесулида у пациентов, находящихся на терапии препаратами лития, следует осуществлять регулярный контроль концентрации лития в плазме крови.\u003Cbr\u003EКлинически значимых взаимодействий с глибенкламидом, теофиллином, дигоксином, циметидином и антацидными препаратами (например, комбинация алюминия и магния гидроксидов) не наблюдалось.\u003Cbr\u003EНимесулид подавляет активность изофермента СYР2С9. При одновременном применении с нимесулидом препаратов, являющихся субстратами этого фермента, концентрация последних в плазме может повышаться.\u003Cbr\u003EПри назначении нимесулида менее чем за 24 часа до или после приема метотрексата требуется соблюдать осторожность, так как в таких случаях уровень метотрексата в плазме крови и, соответственно, токсические эффекты могут повышаться.\u003Cbr\u003EВ связи с действием на почечные простагландины, ингибиторы синтетаз простагландинов, к каким относится нимесулид, могут повышать нефротоксичность циклоспоринов. Исследования in vitro показали, что нимесулид вытесняется из мест связывания толбутамидом, салициловой кислотой и вальпроевой кислотой. Несмотря на то, что данные взаимодействия были определены в плазме крови, указанные эффекты не наблюдались в процессе клинического применения препарата."},{"name":"Регистрационный номер","value":"ЛП-006772"},{"name":"Дата государственной регистрации","value":"11.02.2021"},{"name":"Владелец регистрационного удостоверения","value":"Усолье-Сибирский химфармзавод"},{"name":"Изготовитель","value":"Усолье-Сибирский химфармзавод"},{"name":"Фасовщик","value":"Усолье-Сибирский химфармзавод"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Нимесулид"},{"name":"Срок годности","value":"1 г."}]}],"transitionId":"tr_203505972996798203"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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  • Нимесил гран. д/приг. сусп. д/вн. приема пак., 100 мг, 2 г, 9 шт.
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    Нимесил гран. д/приг. сусп. д/вн. приема пак., 100 мг, 2 г, 9 шт.

    Рейтинг товара: 4.9 из 5
    на основе 297 оценок
    Цена 438 ₽
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  • Нимесулид таб., 100 мг, 30 шт.
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    Нимесулид таб., 100 мг, 30 шт.

    Рейтинг товара: 4.8 из 5
    на основе 363 оценки
    Цена 90 ₽
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  • Нимесулид гран. д/приг. сусп. д/вн. приема пак., 100 мг, 9 шт.
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    Нимесулид гран. д/приг. сусп. д/вн. приема пак., 100 мг, 9 шт.

    Рейтинг товара: 4.8 из 5
    на основе 55 оценок
    Цена 202 ₽
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  • Нимесулид гран. д/приг. сусп. д/вн. приема пак., 100 мг, 2 г, 4 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-haszn9fytva/toggleWishlist":{"skuId":"101392567754","productId":667252000,"offerId":"S-lRwXo2Ttx5HwnqsKlNqQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQzv2L4oLajb5MEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIoOqVvgIQypvf2/kCGOvL9Qcg59zBBw==","sign":"1vU0ojkQACltb/E3NFHlBtINZhagiXvOc5WbW8Qas4k="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-haszn9fytva/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Нимесулид гран. д/приг. сусп. д/вн. приема пак., 100 мг, 2 г, 4 шт.

    Рейтинг товара: 5 из 5
    на основе 2 оценки
    Цена 124 ₽
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  • Нимесулид-МБФ гран. д/приг. сусп. д/вн. приема, 100 мг, 2 г, 5 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-081eewau3lk5/toggleWishlist":{"skuId":"101392460730","productId":662107000,"offerId":"HKZK-u_vU4rigGYVBjaepg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQzv2L4oLajb5MEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcI+ObbuwIQutfY2/kCGJHqkAcg59zBBw==","sign":"LDqlwEeYShy9fQgVDIX3z8nF01cJekRXjLLX8qM4UqU="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-081eewau3lk5/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Нимесулид-МБФ гран. д/приг. сусп. д/вн. приема, 100 мг, 2 г, 5 шт.

    Рейтинг товара: 4.9 из 5
    на основе 41 оценка
    Цена 132 ₽
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  • Нимесил гран. д/приг. сусп. д/вн. приема пак., 100 мг, 2 г, 30 шт.
    –21 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-c68mf6bdnae/toggleWishlist":{"skuId":"1014093533","productId":1778170754,"offerId":"GqR6S92C7u2ZCRt-Cola2g","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQzv2L4oLajb5MEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYIgvfyzwYQ3a3H4wMYjoSKESDn3MEH","sign":"pz6zgOrvFHalk6Yp5F3o9Y087p0ba6dzciRUxItEoug="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-c68mf6bdnae/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Нимесил гран. д/приг. сусп. д/вн. приема пак., 100 мг, 2 г, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 89 оценок
    Цена 1 084 ₽ вместо 1 373
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  • Нимесулид-ЛекТ таб., 100 мг, 20 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-vkr7kkwvy7r/toggleWishlist":{"skuId":"101359406740","productId":991452075,"offerId":"gSlhLMX8AaMyewhRqfQdBw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQzv2L4oLajb5MEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIq7fh2AMQlJ33y/kCGM6niREg59zBBw==","sign":"ZxeXTZ6PbG2YlUwtIaONEdEWQgderIHglUNNF3bfhq0="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-vkr7kkwvy7r/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Нимесулид-ЛекТ таб., 100 мг, 20 шт.

    Рейтинг товара: 4.9 из 5
    на основе 129 оценок
    Цена 85 ₽
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  • Нимесулид Реневал таб., 100 мг, 20 шт.
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    Нимесулид Реневал таб., 100 мг, 20 шт.

    Рейтинг товара: 4.8 из 5
    на основе 32 оценки
    Цена 83 ₽
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  • Немулекс гран. д/пригот. сусп. д/вн. приема, 100 мг, 2 г, 10 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-yc4w93nyx7/toggleWishlist":{"skuId":"186868794","productId":1422663436,"offerId":"AOrNLNCJL2FuvJk0uwf9AA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQzv2L4oLajb5MEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIjL6wpgUQusiNWRig6pAHIOfcwQc=","sign":"uPQjXP81pRta29subkABJOX5BgGsUX0UMrK7/tr2iP0="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-yc4w93nyx7/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Немулекс гран. д/пригот. сусп. д/вн. приема, 100 мг, 2 г, 10 шт.

    Рейтинг товара: 5 из 5
    на основе 10 оценок
    Цена 351 ₽
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  • Нимесулид таб., 100 мг, 30 шт.
    –22 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-72m6lmu3sva/toggleWishlist":{"skuId":"101392443729","productId":526944152,"offerId":"MX1tS1o79RcId0qBTryA6A","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQzv2L4oLajb5MEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcImI+i+wEQ0dLX2/kCGISpsggg59zBBw==","sign":"JTI0iKle78NQt+m4m5omgjjn+v7JsFHOAD5KuWGmqWc="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-72m6lmu3sva/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Нимесулид таб., 100 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 37 оценок
    Цена 174 ₽ вместо 224
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  • Найз таб., 100 мг, 20 шт.
    –14 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-u46as5lxc4/toggleWishlist":{"skuId":"101392131734","productId":228052583,"offerId":"o4bPWF7esK7XtdXAJWgZVQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQzv2L4oLajb5MEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYI55zfbBCWzcTb+QIYwKLVByDn3MEH","sign":"6PAhrxQJtBkibpkk6Py3BuiIkc1umReKgAfjc/0fq4Y="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-u46as5lxc4/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Найз таб., 100 мг, 20 шт.

    Рейтинг товара: 4.8 из 5
    на основе 34 оценки
    Цена 274 ₽ вместо 318
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  • Анальгин таб., 500 мг, 20 шт.
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    Анальгин таб., 500 мг, 20 шт.

    Рейтинг товара: 5 из 5
    на основе 8 оценок
    Цена 65 ₽
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Инструкция

Показания к применению

Терапия острой боли:
- боль в нижней части спины и/или области поясницы;
- болевой синдром, связанный с заболеваниями опорно-двигательного аппарата, в том числе тендиниты, бурситы;
- боль при ушибах, растяжениях связок и вывихах суставов;
- зубная боль;
- симптоматическое лечение остеоартроза (остеоартрита) с болевым синдромом;
- первичная альгодисменорея.
Препарат предназначен для симптоматической терапии, уменьшения боли и воспаления на момент использования, на прогрессирование заболевания не влияет. Нимесулид рекомендуется для терапии в качестве препарата второй линии.

Противопоказания

- Повышенная чувствительность к нимесулиду или другим компонентам препарата;
- Полное или неполное сочетание бронхиальной астмы, рецидивирующего полипоза носа, околоносовых пазух и непереносимость ацетилсалициловой кислоты и других НПВП (в т.ч. в анамнезе);
- Гепатотоксические реакции на нимесулид в анамнезе;
- Одновременное применение с другими лекарственными препаратами с потенциальной гепатотоксичностью (например, другими НПВП);
- Хронические воспалительные заболевания кишечника (болезнь Крона, язвенный колит) в фазе обострения;
- Период после аортокоронарного шунтирования;
- Лихорадочный синдром при простуде и острых респираторно-вирусных инфекциях;
- Подозрение на острую хирургическую патологию;
- Язвенная болезнь желудка или двенадцатиперстной кишки в фазе обострения;
- Эрозивно-язвенное поражение желудочно-кишечного тракта в фазе обострения;
- Эрозивно-язвенное поражение желудочно-кишечного тракта в анамнезе;
- Перфорации или желудочно-кишечные кровотечения в анамнезе, в том числе связанные с предшествующей терапией НПВП;
- Цереброваскулярные кровотечения в анамнезе, другие активные кровотечения или заболевания, сопровождающиеся повышенной кровоточивостью;
- Тяжелые нарушения свертывания крови;
- Тяжелая сердечная недостаточность;
- Тяжелая почечная недостаточность (клиренс креатинина менее 30 мл/мин);
- Прогрессирующее заболевание почек;
- Подтвержденная гиперкалиемия;
- Печеночная недостаточность, активное заболевание печени;
- Детский возраст до 12 лет;
- Беременность и период грудного вскармливания;
- Алкоголизм, наркотическая зависимость, дефицит сахаразы/изомальтазы, непереносимость фруктозы, глюкозо-галактозная мальабсорбция, так как препарат содержит сахарозу.

Способ применения и дозы

Внутрь. Взрослым и детям старше 12 лет внутрь (масса тела более 40 кг) назначают по 100 мг 2 раза в день. Принимают после еды с достаточным количеством воды. Максимальная суточная доза для взрослых и детей старше 12 лет составляет 200 мг.
Пациенты пожилого возраста: при терапии пожилых пациентов коррекция суточной дозы не требуется.
Пациенты с почечной недостаточностью: у пациентов с почечной недостаточностью легкой и умеренной степени тяжести (клиренс креатинина 30-60 мл/мин) коррекция дозы не требуется, пациентам с тяжелой почечной недостаточностью (клиренс креатинина меньше 30 мл/мин) нимесулид противопоказан.
Пациенты с печеночной недостаточностью: применение нимесулида у пациентов с печеночной недостаточностью противопоказано.
Курс лечения: по назначению врача. Для уменьшения вероятности развития побочных эффектов рекомендуется принимать минимальную эффективную дозу в течение минимально короткого времени. Максимальная продолжительность курса лечения нимесулидом - 15 дней.
Полная инструкция
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Нимесулид гран. д/приг. сусп. д/вн. приема
Нимесулид гран. д/приг. сусп. д/вн. приема, 100 мг, 2 г, 30 шт.
4.8
(82)
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1 вопрос
Инструкция

390 ₽

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4.8
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У продавца:82 оценки·25 отзывов
У всех продавцов:84 оценки·27 отзывов
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user avatar
Год назад • Натали К. • Куплен на Маркете
Достоинства: Очень быстрая доставка, спасибо!
Недостатки: Только один. Заказ получен, но яндекс маркет шлёт уведомление что заказ нужно получить
Комментарий: Искала где дешевле, нашла тут. Разница по деньгам ощутимая, это не 10-20 рублей. Препарат хороший, иногда нуждаюсь в нём.
user avatar
4 месяца назад • Ирина Перова • Куплен на Маркете
Достоинства: легко растворяется в воде
Недостатки: нет
Комментарий: мне помогает при боли в суставах и при повышенной температуре
user avatar
3 месяца назад • Ирина Салова • Куплен на Маркете
Достоинства: количество в упаковке по хорошей цене
Недостатки: нет
Комментарий: надолго хватит. цена хорошая
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  • Нимесил гран. д/приг. сусп. д/вн. приема пак., 100 мг, 2 г, 9 шт.
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    Нимесил гран. д/приг. сусп. д/вн. приема пак., 100 мг, 2 г, 9 шт.

    Цена 438 ₽
  • Жидкий пластырь Fixplast c пантенолом, 60 мл
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    Жидкий пластырь Fixplast c пантенолом, 60 мл

    Цена 355 ₽ вместо 399
  • Нимесулид таб., 100 мг, 30 шт.
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    Нимесулид таб., 100 мг, 30 шт.

    Цена 90 ₽
  • Нимесулид гран. д/приг. сусп. д/вн. приема пак., 100 мг, 9 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1744991704_3/content/content/toggleWishlist":{"skuId":"101740868298","productId":1744991704,"offerId":"TZzbmCeqMgZCDgkf3haguA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQzv2L4oLajb5MEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIXCNjricAGEMrl6YH7AhiX0JAHIOfcwQc=","sign":"4vDsMUOc2e8DpB7t/PLyOYFyBKH4Veb0nSmI2HsMr+4="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1744991704_3/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Нимесулид гран. д/приг. сусп. д/вн. приема пак., 100 мг, 9 шт.

    Цена 202 ₽
  • Нимесулид гран. д/приг. сусп. д/вн. приема пак., 100 мг, 2 г, 4 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:667252000_4/content/content/toggleWishlist":{"skuId":"101392567754","productId":667252000,"offerId":"S-lRwXo2Ttx5HwnqsKlNqQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQzv2L4oLajb5MEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIXCKDqlb4CEMqb39v5Ahjry/UHIOfcwQc=","sign":"0h364fkVrAKQheCmUTAW2emUm9avq0PmlL7m9plkI2c="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:667252000_4/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Нимесулид гран. д/приг. сусп. д/вн. приема пак., 100 мг, 2 г, 4 шт.

    Цена 124 ₽
  • Нимесулид-МБФ гран. д/приг. сусп. д/вн. приема, 100 мг, 2 г, 5 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:662107000_5/content/content/toggleWishlist":{"skuId":"101392460730","productId":662107000,"offerId":"HKZK-u_vU4rigGYVBjaepg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQzv2L4oLajb5MEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIXCPjm27sCELrX2Nv5AhiR6pAHIOfcwQc=","sign":"W1Z/nb0pJKQ/NjsIwdEkHn8QSSLKJYzAeZ5S809I8a4="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:662107000_5/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Нимесулид-МБФ гран. д/приг. сусп. д/вн. приема, 100 мг, 2 г, 5 шт.

    Цена 132 ₽
  • Нимесил гран. д/приг. сусп. д/вн. приема пак., 100 мг, 2 г, 30 шт.
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    Нимесил гран. д/приг. сусп. д/вн. приема пак., 100 мг, 2 г, 30 шт.

    Цена 1 084 ₽ вместо 1 373
  • Нимесулид-ЛекТ таб., 100 мг, 20 шт.
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    Нимесулид-ЛекТ таб., 100 мг, 20 шт.

    Цена 85 ₽
  • {"widgets":{"@light/BannerCurtain":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_101_8/content/content/content/bannerCurtain":{"advertisementId":2071421,"impression":"/safeclick/data=SpQw45JhDGE6zDtOdUQO_HcJB4i-wRmE0HcHl_5Egdhw8Pm8UJd_q-myMBRTxLEgSZhZKEszFieT9FQtVeNhjF-I35hAfK71akUDkkZuU-sF0LNAkmZibeZHcAk7JDqMNkCCnprh5SdusACWU9R0hp4SB6WGosVIbVL3-0GKoS4-F6tDfVoEjzLN7739Bewnw44dKyKbS5Otqo3EjWDPkAXXe5UNeQPEcikxbkd1gtcNfE--5QX3SiCJcDhK4et__8IPCOTsGUABYh4Y2MsvrqGtcyUuZXLdXEKnhm8d2XKgOJrK_4vgxyO8V_Rzww3S51X-mC-t-wQ6goqwemOf0JnPf3n026uhO4aVacm83dCf3jNZ19atOknK2eFReySISlUUtGFqjNGhkJkT26sLYHum9XrS-ZApFfYj9F_U4MN0J6NBK8jpiY6ns0p0dvwbS5TEegyrIR-MGTBNZZXnGkNxiQdBs5g-A7OeNoIR19WCBayBdNHNFkVxip1Hnhr8YcrlxNI16oCl6s-dlURLFJd1QXsKN5NUvdGfF09jaMyVNCqFZXJlCqC1S1LWGB1nySnJRESBnb2c76tR5B7NVYPexxvY8-CU4tYMGUTvt3V-Y0KEAuhaVTxCTuJhpnQBWv4c4Szvbh-LmcoQ2lqfoOpljxDrpnG17wxAXqXMrnT7kUo-h5lwOC6xrBdDVS21swJKi3nwUQGDi5UJKw_N1B1-8tpsz-Li2MBDW539ult41CHqfOo-VRT_y_O0kbhKngA51jzGixWvDMpyf2zeNcdR3WPUeGxnBjqtakO_92QGXSqS5EdCXEP5Q7q3P1A11FUp3PwHtaN-jp7BKojVwfn9W3az20OhzjhtCej7WJygM2t9SgRscgE10Uts5iVGHh-teINi_kmeRkiOqDkHpR1QYLRU_QM-XoT_L9B2mZO4hAdnkjup9QDMNjzGH7gpxgxuEwITH1q1HcoT-jr0yuI8QjInrnyWItXtNYSpAPrPrnQWiWQs6q89ihJqRLTca59z4VOc6wxl46WYflSFMxuvDV7l8I1BdLFN1S_tC8CtEhJDRsSJq8yyqQIDtHdR85PO73punVT3A8pj23jWcw,,/b64e=1/sign=b37b5efeff9d31e24aec0abe9fdaa252/keyno=MARKET_1/*"}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_101_8/content/content/content/bannerCurtain":{"name":"@light/BannerCurtain"}}}
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    Реклама
    {"widgets":{"@light/AdLabel":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_101_8/content/content/content/adLabel":{"adLabel":{"adLabelText":"Реклама","advertizer":"АКЦИОНЕРНОЕ ОБЩЕСТВО \"АЛЬФА-БАНК\", ИНН 7728168971, ID #e-1g-105699-VND-ADV","adLabel":1},"advertisementId":2071421,"allowDebug":false,"borderRadius":5,"indents":6}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_101_8/content/content/content/adLabel":{"name":"@light/AdLabel"}}}
    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  • Нимесулид Реневал таб., 100 мг, 20 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:795193043_9/content/content/gallery":{"title":"Нимесулид Реневал таб., 100 мг, 20 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/5345452/img_id6258027812247983881.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5345452/img_id6258027812247983881.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5345452/img_id6258027812247983881.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5345452/img_id6258027812247983881.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5345452/img_id6258027812247983881.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5345452/img_id6258027812247983881.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4709279/img_id8305392606540769829.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4709279/img_id8305392606540769829.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4709279/img_id8305392606540769829.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4709279/img_id8305392606540769829.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4709279/img_id8305392606540769829.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4709279/img_id8305392606540769829.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQzv2L4oLajb5MEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIXCNPdlvsCELzU2dv5AhjyrIIIIOfcwQc=","sign":"iudcSapMsNPqihej9vSPKEeBlIj013ANPnX6FkjDwGc="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:795193043_9/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
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    Нимесулид Реневал таб., 100 мг, 20 шт.

    Цена 83 ₽
  • Vitamin D3, 50000 МЕ, 50 мл, 50 шт.
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    Vitamin D3, 50000 МЕ, 50 мл, 50 шт.

    Цена 1 355 ₽ вместо 1 940
  • Пастилки California Gold Nutrition Vitamin D3 gummies со вкусом фруктов и ягод, 280 г, 90 шт.
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    Пастилки California Gold Nutrition Vitamin D3 gummies со вкусом фруктов и ягод, 280 г, 90 шт.

    Цена 411 ₽ вместо 443
  • Контрактубекс гель, 20 мл, 20 г
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    Контрактубекс гель, 20 мл, 20 г

    Цена 845 ₽ вместо 854
  • Д-пантенол крем, 30 мл, 30 г, 1 шт., 1 уп.
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    Д-пантенол крем, 30 мл, 30 г, 1 шт., 1 уп.

    Цена 208 ₽ вместо 231
  • Гилан ультра комфорт увлажн. гл. р-р, 0.3%, 0.4 мл, 50 г, 10 шт.
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    Гилан ультра комфорт увлажн. гл. р-р, 0.3%, 0.4 мл, 50 г, 10 шт.

    Цена 288 ₽ вместо 331
  • БиоГая Пробиотик капли детск. фл., 5 мл, 1 уп.
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    БиоГая Пробиотик капли детск. фл., 5 мл, 1 уп.

    Цена 1 752 ₽ вместо 3 500
  • Немулекс гран. д/пригот. сусп. д/вн. приема, 100 мг, 2 г, 10 шт.
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    Немулекс гран. д/пригот. сусп. д/вн. приема, 100 мг, 2 г, 10 шт.

    Цена 351 ₽
  • Нимесулид таб., 100 мг, 30 шт.
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    Нимесулид таб., 100 мг, 30 шт.

    Цена 174 ₽ вместо 224
  • Эвалар Чай Эвалар БИО при повышенном содержании мочевой кислоты, 20 фильтр-пакетов
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    Эвалар Чай Эвалар БИО при повышенном содержании мочевой кислоты, 20 фильтр-пакетов

    Цена 194 ₽ вместо 224
  • Марля медицинская повышенной плотности, отрез 3 метра
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    Марля медицинская повышенной плотности, отрез 3 метра

    Цена 157 ₽ вместо 199
  • Гилан Комфорт увлажн. гл. р-р, 0.18%, 0.4 мл, 30 шт.
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    Гилан Комфорт увлажн. гл. р-р, 0.18%, 0.4 мл, 30 шт.

    Цена 359 ₽
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    Реклама
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  • ЛимфоТранзит концентрат напитка фл., 100 мл
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    ЛимфоТранзит концентрат напитка фл., 100 мл

    Цена 329 ₽ вместо 390
  • Найз таб., 100 мг, 20 шт.
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    Найз таб., 100 мг, 20 шт.

    Цена 274 ₽ вместо 318
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