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Нурофен форте таб. п/о, 400 мг, 24 шт.

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4.9
(181)
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Количество штук в упаковке, шт.: 24

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Коротко о товаре

Артикул Маркета
3900475635
Тип препарата
Назначение
Действующее вещество
Возраст
от 12 лет
Инструкция
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а также при лихорадочном состоянии при гриппе и простудных заболеваниях."},{"name":"Противопоказания","value":"Гиперчувствительность к ибупрофену или любому из компонентов, входящих в состав препарата.\u003Cbr\u003EПолное или неполное сочетание бронхиальной астмы, рецидивирующего полипоза носа и околоносовых пазух, и непереносимости ацетилсалициловой кислоты или других НПВП (в том числе в анамнезе).\u003Cbr\u003EЭрозивно-язвенные заболевания органов желудочно-кишечного тракта (в том числе язвенная болезнь желудка и двенадцатиперстной кишки, болезнь Крона, язвенный колит) или язвенное кровотечение в активной фазе или в анамнезе (два или более подтвержденных эпизода язвенной болезни или язвенного кровотечения).\u003Cbr\u003EКровотечение или перфорация язвы желудочно-кишечного тракта в анамнезе, спровоцированные применением НПВП.\u003Cbr\u003EТяжелая сердечная недостаточность (класс IV по NYHA - классификация Нью-Йоркской Ассоциации кардиологов).\u003Cbr\u003EТяжелая печеночная недостаточность или заболевание печени в активной фазе.\u003Cbr\u003EПочечная недостаточность тяжелой степени тяжести (клиренс креатинина \u003C 30 мл/мин), подтвержденная гиперкалиемия.\u003Cbr\u003EДекомпенсированная сердечная недостаточность; период после проведения аортокоронарного шунтирования.\u003Cbr\u003EЦереброваскулярное или иное кровотечение.\u003Cbr\u003EНепереносимость фруктозы, глюкозо-галактозная мальабсорбция,недостаточность сахаразы-изомальтазы.\u003Cbr\u003EГемофилия и другие нарушения свертываемости крови (в том числе гипокоагуляция), геморрагические диатезы.\u003Cbr\u003EБеременность (III триместр).\u003Cbr\u003EДетский возраст до 12 лет."},{"name":"Состав","value":"Одна таблетка, покрытая оболочкой, содержит:\u003Cbr\u003Eдействующее вещество: ибупрофена 400 мг;\u003Cbr\u003Eвспомогательные вещества: кроскармеллоза натрия 60 мг, натрия лаурилсульфат 1 мг, натрия цитрат 87 мг, стеариновая кислота 4 мг, кремния диоксид коллоидный 2 мг.\u003Cbr\u003Eсостав оболочка: кармеллоза натрия 1,4 мг. тальк 66 мг, акации камедь 1,2 мг, сахароза 232,2 мг, титана диоксид 2,8 мг, макрогол 6000 0,4 мг, чернила красные [Опакод S-1-15094] (шеллак 41,49 %, краситель железа оксид красный (Е172) 31 %, буганол* 14 %, изопропанол* 7 %, пропиленгликоль 5,5 %, аммиак водный 1 %, симетикон 0,01 %).\u003Cbr\u003E*Растворители, испарившиеся после процесса печати."},{"name":"Действующее вещество","value":"Ибупрофен","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["27144131:28710587"]}}},{"name":"Способ применения и дозы","value":"Для приема внутрь. Пациентам с повышенной чувствительностью желудка рекомендуется принимать препарат во время еды.\u003Cbr /\u003EТолько для кратковременного применения. Внимательно прочтите инструкцию перед приемом препарата.\u003Cbr /\u003EВзрослым и детям старше 12 лет внутрь по 1 таблетке (400 мг) до З раз в сутки.\u003Cbr /\u003EТаблетки следует запивать водой.\u003Cbr /\u003EИнтервал между приемом таблеток должен составлять не менее 6 часов.\u003Cbr /\u003EМаксимальная суточная доза составляет 1200 мг (З таблетки). Максимальная суточная доза для детей от 12 до 1 8 лет составляет 800 мг (2 таблетки).\u003Cbr /\u003EЕсли при приеме препарата в течение 2-3 дней симптомы сохраняются или усиливаются, необходимо прекратить лечение и обратиться к врачу.\u003Cbr /\u003E"},{"name":"Побочные действия","value":"Риск возникновения побочных эффектов можно свести к минимуму, если принимать препарат коротким курсом в минимальной эффективной дозе, необходимой для устранения симптомов.\u003Cbr\u003EУ пациентов пожилого возраста наблюдается повышенная частота побочных реакций на фоне применения НПВС, особенно желудочно-кишечных кровотечений и перфораций, в некоторых случаях с летальным исходом.\u003Cbr\u003EПобочные эффекты преимущественно являются дозозависимыми.\u003Cbr\u003EНижеперечисленные побочные реакции отмечались при кратковременном применении ибупрофена в дозах, не превышающих 1200 мг/сут (3 таб.). При лечении хронических состояний и при длительном применении возможно появление других побочных реакций.\u003Cbr\u003EОценка частоты возникновения побочных реакций произведена на основании следующих критериев: очень часто (≥1/10), часто (от ≥1/100 до \u003C1/10), нечасто (от ≥1/1000 до \u003C1/100), редко (от ≥1/10 000 до \u003C1/1000), очень редко (\u003C1/10 000), частота неизвестна (данные по оценке частоты отсутствуют).\u003Cbr\u003EСо стороны системы кроветворения: очень редко - нарушения кроветворения (анемия, лейкопения, апластическая анемия, гемолитическая анемия, тромбоцитопения, панцитопения, агранулоцитоз). Первыми симптомами таких нарушений являются лихорадка, боль в горле, поверхностные язвы в полости рта, гриппоподобные симптомы, выраженная слабость, кровотечения из носа и подкожные кровоизлияния, кровотечения и кровоподтеки неизвестной этиологии.\u003Cbr\u003EСо стороны иммунной системы: нечасто - реакции гиперчувствительности (неспецифические аллергические реакции и анафилактические реакции), реакции со стороны дыхательных путей (бронхиальная астма, в т.ч. ее обострение, бронхоспазм, одышка, диспноэ), кожные реакции (зуд, крапивница, пурпура, отек Квинке, эксфолиативные и буллезные дерматозы, в т.ч. токсический эпидермальный некролиз (синдром Лайелла), синдром Стивенса-Джонсона, многоформная эритема), аллергический ринит, эозинофилия; очень редко - тяжелые реакции гиперчувствительности, в т.ч. отек лица, языка и гортани, одышка, тахикардия, артериальная гипотензия (анафилаксия, отек Квинке или тяжелый анафилактический шок).\u003Cbr\u003EСо стороны ЖКТ: нечасто - боль в животе, тошнота, диспепсия (в т.ч. изжога, вздутие живота); редко - диарея, метеоризм, запор, рвота; очень редко - пептическая язва, перфорация или желудочно-кишечное кровотечение, мелена, кровавая рвота, в некоторых случаях с летальным исходом, особенно у пациентов пожилого возраста, язвенный стоматит, гастрит; частота неизвестна - обострение колита и болезни Крона.\u003Cbr\u003EСо стороны печени и желчевыводящих путей: очень редко - нарушения функции печени, повышение активности печеночных трансаминаз, гепатит и желтуха.\u003Cbr\u003EСо стороны мочевыделительной системы: очень редко - острая почечная недостаточность (компенсированная и декомпенсированная) особенно при длительном применении, в сочетании с повышением концентрации мочевины в плазме крови и появлением отеков, гематурии и протеинурии, нефритический синдром, нефротический синдром, папиллярный некроз, интерстициальный нефрит, цистит.\u003Cbr\u003EСо стороны нервной системы: нечасто - головная боль; очень редко - асептический менингит.\u003Cbr\u003EСо стороны сердечно-сосудистой системы: частота неизвестна - сердечная недостаточность, периферические отеки, при длительном применении повышен риск тромботических осложнений (например, инфаркт миокарда), повышение АД.\u003Cbr\u003EСо стороны дыхательной системы: частота неизвестна - бронхиальная астма, бронхоспазм, одышка.\u003Cbr\u003EЛабораторные показатели: гематокрит или гемоглобин могут уменьшаться; время кровотечения может увеличиваться; концентрация глюкозы в плазме крови может снижаться; клиренс креатинина может уменьшаться; плазменная концентрация креатинина может увеличиваться; активность печеночных трансаминаз может повышаться.\u003Cbr\u003EПри появлении побочных эффектов следует прекратить прием препарата и обратиться к врачу."},{"name":"Фармакологическое действие","value":"Механизм действия ибупрофена, производного пропионовой кислоты из группы нестероидных противовоспалительных препаратов (НПВП), обусловлен ингибированием синтеза простагландинов медиаторов боли, воспаления и гипертермической реакции. Неизбирательно блокирует циклооксигеназу 1 (ЦОГ-1) и циклооксигеназу 2 (ЦОГ-2), вследствие чего тормозит синтез простагландинов. Оказывает быстрое направленное действие против боли (обезболивающее), жаропонижающее и противовоспалительное действие. Кроме того, ибупрофен обратимо ингибирует агрегацию тромбоцитов. Обезболивающее действие препарата продолжается до 8 часов."},{"name":"Фармакологическая группа","value":"нестероидный противовоспалительный препарат (НПВП)"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 12 лет"},{"name":"Продолжительность действия","value":"8 часов"},{"name":"Условия хранения","value":"Препарат следует хранить в недоступном для детей месте при температуре не выше 25°С."},{"name":"Передозировка","value":"У детей симптомы передозировки могут возникать после приема препарата в дозе, превышающей 400 мг/кг массы тела. У взрослых дозозависимый эффект передозировки менее выражен. Т1/2 препарата при передозировке составляет 1.5-3 ч.\u003Cbr\u003EСимптомы: тошнота, рвота, боль в эпигастральной области или, реже, диарея, шум в ушах, головная боль и желудочно-кишечное кровотечение. В более тяжелых случаях наблюдаются проявления со стороны ЦНС: сонливость, редко – возбуждение, судороги, дезориентация, кома. В случаях тяжелого отравления может развиваться метаболический ацидоз и увеличение протромбинового времени, почечная недостаточность, повреждение ткани печени, снижение АД, угнетение дыхания и цианоз. У пациентов с бронхиальной астмой возможно обострение этого заболевания.\u003Cbr\u003EЛечение: симптоматическое, с обязательным обеспечением проходимости дыхательных путей, мониторингом ЭКГ и основных показателей жизнедеятельности вплоть до нормализации состояния пациента. Рекомендуется пероральное применение активированного угля или промывание желудка в течение 1 ч после приема потенциально токсической дозы ибупрофена. Если ибупрофен уже абсорбировался, может быть назначено щелочное питье с целью выведения кислого производного ибупрофена почками, форсированный диурез. Частые или продолжительные судороги следует купировать в/в введением диазепама или лоразепама. При усугублении бронхиальной астмы рекомендуется применение бронходилататоров."},{"name":"Применение при беременности и кормлении грудью","value":"Противопоказано применение препарата в III триместре беременности. Следует избегать применения препарата в I-II триместрах беременности, при необходимости приема препарата следует проконсультироваться с врачом. Имеются данные о том, что ибупрофен в незначительных количествах может проникать в грудное молоко без каких-либо отрицательных последствий для здоровья грудного ребенка, поэтому обычно при кратковременном приеме необходимости в прекращении грудного вскармливания не возникает. При необходимости длительного применения препарата следует обратиться к врачу для решения вопроса о прекращении грудного вскармливания на период применения препарата."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Пациентам, отмечающим головокружение, сонливость, заторможенность или нарушения зрения при приеме ибупрофена, следует избегать вождения автотранспорта или управления механизмами."},{"name":"Особые указания","value":"Рекомендуется принимать препарат максимально возможным коротким курсом и в минимальной эффективной дозе, необходимой для устранения симптомов. В случае необходимости приема препарата более 10 дней, необходимо обратиться к врачу.\u003Cbr\u003EУ пациентов с бронхиальной астмой или аллергическим заболеванием в стадии обострения, а также у пациентов с анамнезом бронхиальной астмы/аллергического заболевания препарат может спровоцировать бронхоспазм. Применение препарата у пациентов с системной красной волчанкой или смешанным заболеванием соединительной ткани связано с повышенным риском развития асептического менингита.\u003Cbr\u003EВо время длительного лечения необходим контроль картины периферической крови и функционального состояния печени и почек. При появлении симптомов гастропатии показан тщательный контроль, включающий проведение эзофагогастродуоденоскопии, общий анализ крови (определение гемоглобина), анализ кала на скрытую кровь. При необходимости определения 17-кетостероидов препарат следует отменить за 48 часов до исследования. В период лечения не рекомендуется прием этанола.\u003Cbr\u003EПациентам с почечной недостаточностью необходимо проконсультироваться с врачом перед применением препарата, поскольку существует риск ухудшения функционального состояния почек.\u003Cbr\u003EПациентам с гипертонией, в том числе в анамнезе и/или хронической сердечной недостаточностью, необходимо проконсультироваться с врачом перед применением препарата, поскольку препарат может вызывать задержку жидкости, повышение артериального давления и отеки.\u003Cbr\u003EПациентам с неконтролируемой артериальной гипертензией, застойной сердечной недостаточностью II-III класса по NYHA, ишемической болезнью сердца, заболеваниями периферических артерий и/или цереброваскулярными заболеваниями назначать ибупрофен следует только после тщательной оценки соотношения польза-риск, при этом следует избегать применения высоких доз ибупрофена (≥2400 мг/сутки).\u003Cbr\u003EПрименение НПВП у пациентов с ветряной оспой может быть связано с повышенным риском развития тяжелых гнойных осложнений инфекционно¬воспалительных заболеваний кожи и подкожно-жировой клетчатки (например, некротизирующего фасциита). В связи с этим рекомендуется избегать применения препарата при ветряной оспе.\u003Cbr\u003EИнформация для женщин, планирующих беременность: препарат подавляет циклооксигеназу и синтез простагландинов, воздействует на овуляцию, нарушая женскую репродуктивную функцию (обратимо после отмены лечения).\u003Cbr\u003EС осторожностью:\u003Cbr\u003EПри наличии состояний, указанных в данном разделе, перед применением препарата следует обратиться к врачу.\u003Cbr\u003EОдновременный прием других НПВП, наличие в анамнезе однократного эпизода язвенной болезни желудка и двенадцатиперстной кишки или язвенного кровотечения ЖКТ; гастрит, энтерит, колит, наличие инфекции Helicobacter pylori, язвенный колит; бронхиальная астма или аллергические заболевания в стадии обострения или в анамнезе - возможно развитие бронхоспазма; системная красная волчанка или смешанное заболевание соединительной ткани (синдром Шарпа) - повышен риск асептического менингита; ветряная оспа; почечная недостаточность, в том числе при обезвоживании (клиренс креатинина менее 30-60 мл/мин), нефротический синдром, печеночная недостаточность, цирроз печени с портальной гипертензией, гипербилирубинемия, артериальная гипертензия и/или сердечная недостаточность, цереброваскулярные заболевания, заболевания крови неясной этиологии (лейкопения и анемия), тяжелые соматические заболевания, дислипидемия/гиперлипидемия, сахарный диабет, заболевания периферических артерий, курение, частое употребление алкоголя, одновременное применение лекарственных средств, которые могут увеличить риск возникновения язв или кровотечения, в частности, пероральных глюкокортикостероидов (в том числе преднизолона), антикоагулянтов (в том числе варфарина), селективных ингибиторов обратного захвата серотонина (в том числе циталопрама, флуоксетина, пароксетина, сертралина) или антиагрегантов (в том числе ацетилсалициловой кислоты, клопидогрела), беременность I-II триместр, период грудного вскармливания, пожилой возраст."},{"name":"Взаимодействие","value":"Следует избегать одновременного применения ибупрофена со следующими лекарственными средствами:\u003Cbr /\u003EАцетилсапщиловая\tкислота:\tза\tисключением\tнизких \tдоз\u003Cbr /\u003Eацетилсалициловой кислоты (не более 75 мг в сутки), назначенных врачом, поскольку совместное применение может повысить риск возникновения побочных эффектов. При одновременном применении ибупрофен снижает противовоспалительное и антиагрегантное действие ацетилсалициловой кислоты (возможно повышение частоты развития острой коронарной недостаточности у пациентов, получающих в качестве антиагрегантного средства малые дозы ацетилсалициловой кислоты, после начала приема ибупрофена).\u003Cbr /\u003E Другие НПВП, в частности, селективные ингибиторы ЦОГ-2: следует избегать одновременного применения двух и более препаратов из группы НПВП из-за возможного увеличения риска возникновения побочных эффектов.\u003Cbr /\u003EС осторожностью применять одновременно со следующими лекарственными средствами:\u003Cbr /\u003EАнтикоагулянты и тромболитические препараты: НПВП могут усиливать эффект антикоагулянтов, в частности, варфарина и тромболитических препаратов.\u003Cbr /\u003EАнтигипертензивные средства (ингибиторы АПФ и антагонисты ангиотензина II) и Диуретики.• НПВП могут снижать эффективность препаратов этих групп. У некоторых пациентов с нарушением почечной функции (например, у пациентов с обезвоживанием или у пациентов пожилого возраста с нарушением почечной функции) одновременное назначение ингибиторов АПФ или антагонистов ангиотензина П и средств, ингибирующих циклооксигеназу, может привести к ухудшению почечной функции, включая развитие острой почечной недостаточности (обычно обратимой). Эти взаимодействия следует учитывать у пациентов, принимающих коксибы одновременно с ингибиторами АПФ или антагонистами ангиотензина П. В связи с этим совместное применение вышеуказанных средств следует назначать с осторожностью, особенно у пожилых лиц. Необходимо предотвращать обезвоживание у пациентов, а также рассмотреть возможность мониторинга почечной функции после начала такого комбинированного лечения и периодически — в дальнейшем. Диуретики и ингибиторы АПФ могут повышать нефротоксичность НПВП. ГлюкокортикостероиДы: повышенный риск образования язв )ККТ и желудочно-кишечного кровотечения.\u003Cbr /\u003EАнтиагреганты и селективные ингибиторы обратного захвата серотонина: повышенный риск возникновения желудочно-кишечного кровотечения.\u003Cbr /\u003EСердечные гликозиДы: одновременное назначение НПВП и сердечных гликозидов может привести к усугублению сердечной недостаточности, снижению скорости клубочковой фильтрации и увеличению концентрации сердечных гликозидов в плазме крови.\u003Cbr /\u003EПрепараты лития: существуют данные о вероятности увеличения концентрации лития в плазме крови на фоне применения НПВП.\u003Cbr /\u003EМетотрексат: существуют данные о вероятности увеличения концентрации метотрексата в плазме крови на фоне применения НПВП. Цикчоспорин.• увеличение риска нефротоксичности при одновременном назначении НПВП и циклоспорина.\u003Cbr /\u003EМифепристон.• прием НПВП следует начать не ранее, чем через 8-12 дней после приема мифепристона, поскольку НПВП могут снижать эффективность мифепристона.\u003Cbr /\u003EТакролимус: при одновременном назначении НПВП и такролимуса возможно увеличение риска нефротоксичности.\u003Cbr /\u003EЗиДовуДин: одновременное применение НПВП и зидовудина может привести к повышению гематотоксичности. Имеются данные о повышенном риске возникновения гемартроза и гематом у ВИЧ-положительных пациентов с гемофилией, получавших совместное лечение зидовудином и ибупрофеном.\u003Cbr /\u003EАнтибиотики ХИнОл0н0ВОГО ряда: у пациентов, получающих совместное лечение НПВП и антибиотиками хинолонового ряда, возможно увеличение риска возникновения судорог.\u003Cbr /\u003EМиелотоксические препараты: усиление гематотоксичности.\u003Cbr /\u003EЦефаманДол, цефоперазон, цефотетан, вальпроевая кислота, пликамицин: увеличение частоты развития гипопротромбинемии.\u003Cbr /\u003EЛекарственные средства, блокирующие канальцевую секрецию: снижение выведения и повышение плазменной концентрации ибупрофена.\u003Cbr /\u003EИнДукторы микросомального окисления (фенитоин, этанол, барбитураты, рифампицин, фенилбутазон, трициклические антидепрессанты):\u003Cbr /\u003Eувеличение продукции гидроксилированных активных метаболитов, увеличение риска развития тяжелых интоксикаций.\u003Cbr /\u003EИнгибиторы\tмикросомального\tОКИСЛИИЯ.•\tснижение\tриска гепатотоксического действия.\u003Cbr /\u003EПероральные гипогликемические лекарственные среДства и инсулин, произвоДные сульфонилмочевины: усиление действия препаратов.\u003Cbr /\u003EАнтациды и колестирамин: снижение абсорбции.\u003Cbr /\u003EУрикозурические препараты: снижение эффективности препаратов.\u003Cbr /\u003EЭстрогены, этанол: повышенный риск возникновения побочных эффектов.\u003Cbr /\u003EКофеин: усиление анальгезирующего эффекта."},{"name":"Регистрационный номер","value":"П N016033/01"},{"name":"Дата государственной регистрации","value":"03.03.2023"},{"name":"Владелец регистрационного удостоверения","value":"Reckitt Benckiser","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["34324371:35649313","7893318:13194414"]}}},{"name":"Страна бренда","value":"Великобритания"},{"name":"Страна-производитель","value":"Великобритания"},{"name":"Название препарата","value":"Нурофен","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["17796364:17800221"]}}},{"name":"Срок годности","value":"1 г."}]}},"fullSpecsGrouped":{"17998246143673990352":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Органы и системы","value":"нервная система, опорно-двигательная система"},{"name":"Назначение","value":"альгодисменорея, боль в мышцах, боль в суставах, головная боль, зубная боль, лихорадочные состояния, невралгия"},{"name":"Показания к применению","value":"Нурофен Форте применяют при головной боли, мигрени, зубной боли, болезненных менструациях, невралгии, боли в спине, мышечной боли, ревматической боли и боли в суставах; а также при лихорадочном состоянии при гриппе и простудных заболеваниях."},{"name":"Противопоказания","value":"Гиперчувствительность к ибупрофену или любому из компонентов, входящих в состав препарата.\u003Cbr\u003EПолное или неполное сочетание бронхиальной астмы, рецидивирующего полипоза носа и околоносовых пазух, и непереносимости ацетилсалициловой кислоты или других НПВП (в том числе в анамнезе).\u003Cbr\u003EЭрозивно-язвенные заболевания органов желудочно-кишечного тракта (в том числе язвенная болезнь желудка и двенадцатиперстной кишки, болезнь Крона, язвенный колит) или язвенное кровотечение в активной фазе или в анамнезе (два или более подтвержденных эпизода язвенной болезни или язвенного кровотечения).\u003Cbr\u003EКровотечение или перфорация язвы желудочно-кишечного тракта в анамнезе, спровоцированные применением НПВП.\u003Cbr\u003EТяжелая сердечная недостаточность (класс IV по NYHA - классификация Нью-Йоркской Ассоциации кардиологов).\u003Cbr\u003EТяжелая печеночная недостаточность или заболевание печени в активной фазе.\u003Cbr\u003EПочечная недостаточность тяжелой степени тяжести (клиренс креатинина \u003C 30 мл/мин), подтвержденная гиперкалиемия.\u003Cbr\u003EДекомпенсированная сердечная недостаточность; период после проведения аортокоронарного шунтирования.\u003Cbr\u003EЦереброваскулярное или иное кровотечение.\u003Cbr\u003EНепереносимость фруктозы, глюкозо-галактозная мальабсорбция,недостаточность сахаразы-изомальтазы.\u003Cbr\u003EГемофилия и другие нарушения свертываемости крови (в том числе гипокоагуляция), геморрагические диатезы.\u003Cbr\u003EБеременность (III триместр).\u003Cbr\u003EДетский возраст до 12 лет."},{"name":"Состав","value":"Одна таблетка, покрытая оболочкой, содержит:\u003Cbr\u003Eдействующее вещество: ибупрофена 400 мг;\u003Cbr\u003Eвспомогательные вещества: кроскармеллоза натрия 60 мг, натрия лаурилсульфат 1 мг, натрия цитрат 87 мг, стеариновая кислота 4 мг, кремния диоксид коллоидный 2 мг.\u003Cbr\u003Eсостав оболочка: кармеллоза натрия 1,4 мг. тальк 66 мг, акации камедь 1,2 мг, сахароза 232,2 мг, титана диоксид 2,8 мг, макрогол 6000 0,4 мг, чернила красные [Опакод S-1-15094] (шеллак 41,49 %, краситель железа оксид красный (Е172) 31 %, буганол* 14 %, изопропанол* 7 %, пропиленгликоль 5,5 %, аммиак водный 1 %, симетикон 0,01 %).\u003Cbr\u003E*Растворители, испарившиеся после процесса печати."},{"name":"Действующее вещество","value":"Ибупрофен"},{"name":"Способ применения и дозы","value":"Для приема внутрь. Пациентам с повышенной чувствительностью желудка рекомендуется принимать препарат во время еды.\u003Cbr /\u003EТолько для кратковременного применения. Внимательно прочтите инструкцию перед приемом препарата.\u003Cbr /\u003EВзрослым и детям старше 12 лет внутрь по 1 таблетке (400 мг) до З раз в сутки.\u003Cbr /\u003EТаблетки следует запивать водой.\u003Cbr /\u003EИнтервал между приемом таблеток должен составлять не менее 6 часов.\u003Cbr /\u003EМаксимальная суточная доза составляет 1200 мг (З таблетки). Максимальная суточная доза для детей от 12 до 1 8 лет составляет 800 мг (2 таблетки).\u003Cbr /\u003EЕсли при приеме препарата в течение 2-3 дней симптомы сохраняются или усиливаются, необходимо прекратить лечение и обратиться к врачу.\u003Cbr /\u003E"},{"name":"Побочные действия","value":"Риск возникновения побочных эффектов можно свести к минимуму, если принимать препарат коротким курсом в минимальной эффективной дозе, необходимой для устранения симптомов.\u003Cbr\u003EУ пациентов пожилого возраста наблюдается повышенная частота побочных реакций на фоне применения НПВС, особенно желудочно-кишечных кровотечений и перфораций, в некоторых случаях с летальным исходом.\u003Cbr\u003EПобочные эффекты преимущественно являются дозозависимыми.\u003Cbr\u003EНижеперечисленные побочные реакции отмечались при кратковременном применении ибупрофена в дозах, не превышающих 1200 мг/сут (3 таб.). При лечении хронических состояний и при длительном применении возможно появление других побочных реакций.\u003Cbr\u003EОценка частоты возникновения побочных реакций произведена на основании следующих критериев: очень часто (≥1/10), часто (от ≥1/100 до \u003C1/10), нечасто (от ≥1/1000 до \u003C1/100), редко (от ≥1/10 000 до \u003C1/1000), очень редко (\u003C1/10 000), частота неизвестна (данные по оценке частоты отсутствуют).\u003Cbr\u003EСо стороны системы кроветворения: очень редко - нарушения кроветворения (анемия, лейкопения, апластическая анемия, гемолитическая анемия, тромбоцитопения, панцитопения, агранулоцитоз). Первыми симптомами таких нарушений являются лихорадка, боль в горле, поверхностные язвы в полости рта, гриппоподобные симптомы, выраженная слабость, кровотечения из носа и подкожные кровоизлияния, кровотечения и кровоподтеки неизвестной этиологии.\u003Cbr\u003EСо стороны иммунной системы: нечасто - реакции гиперчувствительности (неспецифические аллергические реакции и анафилактические реакции), реакции со стороны дыхательных путей (бронхиальная астма, в т.ч. ее обострение, бронхоспазм, одышка, диспноэ), кожные реакции (зуд, крапивница, пурпура, отек Квинке, эксфолиативные и буллезные дерматозы, в т.ч. токсический эпидермальный некролиз (синдром Лайелла), синдром Стивенса-Джонсона, многоформная эритема), аллергический ринит, эозинофилия; очень редко - тяжелые реакции гиперчувствительности, в т.ч. отек лица, языка и гортани, одышка, тахикардия, артериальная гипотензия (анафилаксия, отек Квинке или тяжелый анафилактический шок).\u003Cbr\u003EСо стороны ЖКТ: нечасто - боль в животе, тошнота, диспепсия (в т.ч. изжога, вздутие живота); редко - диарея, метеоризм, запор, рвота; очень редко - пептическая язва, перфорация или желудочно-кишечное кровотечение, мелена, кровавая рвота, в некоторых случаях с летальным исходом, особенно у пациентов пожилого возраста, язвенный стоматит, гастрит; частота неизвестна - обострение колита и болезни Крона.\u003Cbr\u003EСо стороны печени и желчевыводящих путей: очень редко - нарушения функции печени, повышение активности печеночных трансаминаз, гепатит и желтуха.\u003Cbr\u003EСо стороны мочевыделительной системы: очень редко - острая почечная недостаточность (компенсированная и декомпенсированная) особенно при длительном применении, в сочетании с повышением концентрации мочевины в плазме крови и появлением отеков, гематурии и протеинурии, нефритический синдром, нефротический синдром, папиллярный некроз, интерстициальный нефрит, цистит.\u003Cbr\u003EСо стороны нервной системы: нечасто - головная боль; очень редко - асептический менингит.\u003Cbr\u003EСо стороны сердечно-сосудистой системы: частота неизвестна - сердечная недостаточность, периферические отеки, при длительном применении повышен риск тромботических осложнений (например, инфаркт миокарда), повышение АД.\u003Cbr\u003EСо стороны дыхательной системы: частота неизвестна - бронхиальная астма, бронхоспазм, одышка.\u003Cbr\u003EЛабораторные показатели: гематокрит или гемоглобин могут уменьшаться; время кровотечения может увеличиваться; концентрация глюкозы в плазме крови может снижаться; клиренс креатинина может уменьшаться; плазменная концентрация креатинина может увеличиваться; активность печеночных трансаминаз может повышаться.\u003Cbr\u003EПри появлении побочных эффектов следует прекратить прием препарата и обратиться к врачу."},{"name":"Фармакологическое действие","value":"Механизм действия ибупрофена, производного пропионовой кислоты из группы нестероидных противовоспалительных препаратов (НПВП), обусловлен ингибированием синтеза простагландинов медиаторов боли, воспаления и гипертермической реакции. Неизбирательно блокирует циклооксигеназу 1 (ЦОГ-1) и циклооксигеназу 2 (ЦОГ-2), вследствие чего тормозит синтез простагландинов. Оказывает быстрое направленное действие против боли (обезболивающее), жаропонижающее и противовоспалительное действие. Кроме того, ибупрофен обратимо ингибирует агрегацию тромбоцитов. Обезболивающее действие препарата продолжается до 8 часов."},{"name":"Фармакологическая группа","value":"нестероидный противовоспалительный препарат (НПВП)"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 12 лет"},{"name":"Продолжительность действия","value":"8 часов"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"Препарат следует хранить в недоступном для детей месте при температуре не выше 25°С."},{"name":"Передозировка","value":"У детей симптомы передозировки могут возникать после приема препарата в дозе, превышающей 400 мг/кг массы тела. У взрослых дозозависимый эффект передозировки менее выражен. Т1/2 препарата при передозировке составляет 1.5-3 ч.\u003Cbr\u003EСимптомы: тошнота, рвота, боль в эпигастральной области или, реже, диарея, шум в ушах, головная боль и желудочно-кишечное кровотечение. В более тяжелых случаях наблюдаются проявления со стороны ЦНС: сонливость, редко – возбуждение, судороги, дезориентация, кома. В случаях тяжелого отравления может развиваться метаболический ацидоз и увеличение протромбинового времени, почечная недостаточность, повреждение ткани печени, снижение АД, угнетение дыхания и цианоз. У пациентов с бронхиальной астмой возможно обострение этого заболевания.\u003Cbr\u003EЛечение: симптоматическое, с обязательным обеспечением проходимости дыхательных путей, мониторингом ЭКГ и основных показателей жизнедеятельности вплоть до нормализации состояния пациента. Рекомендуется пероральное применение активированного угля или промывание желудка в течение 1 ч после приема потенциально токсической дозы ибупрофена. Если ибупрофен уже абсорбировался, может быть назначено щелочное питье с целью выведения кислого производного ибупрофена почками, форсированный диурез. Частые или продолжительные судороги следует купировать в/в введением диазепама или лоразепама. При усугублении бронхиальной астмы рекомендуется применение бронходилататоров."},{"name":"Применение при беременности и кормлении грудью","value":"Противопоказано применение препарата в III триместре беременности. Следует избегать применения препарата в I-II триместрах беременности, при необходимости приема препарата следует проконсультироваться с врачом. Имеются данные о том, что ибупрофен в незначительных количествах может проникать в грудное молоко без каких-либо отрицательных последствий для здоровья грудного ребенка, поэтому обычно при кратковременном приеме необходимости в прекращении грудного вскармливания не возникает. При необходимости длительного применения препарата следует обратиться к врачу для решения вопроса о прекращении грудного вскармливания на период применения препарата."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Пациентам, отмечающим головокружение, сонливость, заторможенность или нарушения зрения при приеме ибупрофена, следует избегать вождения автотранспорта или управления механизмами."},{"name":"Особые указания","value":"Рекомендуется принимать препарат максимально возможным коротким курсом и в минимальной эффективной дозе, необходимой для устранения симптомов. В случае необходимости приема препарата более 10 дней, необходимо обратиться к врачу.\u003Cbr\u003EУ пациентов с бронхиальной астмой или аллергическим заболеванием в стадии обострения, а также у пациентов с анамнезом бронхиальной астмы/аллергического заболевания препарат может спровоцировать бронхоспазм. Применение препарата у пациентов с системной красной волчанкой или смешанным заболеванием соединительной ткани связано с повышенным риском развития асептического менингита.\u003Cbr\u003EВо время длительного лечения необходим контроль картины периферической крови и функционального состояния печени и почек. При появлении симптомов гастропатии показан тщательный контроль, включающий проведение эзофагогастродуоденоскопии, общий анализ крови (определение гемоглобина), анализ кала на скрытую кровь. При необходимости определения 17-кетостероидов препарат следует отменить за 48 часов до исследования. В период лечения не рекомендуется прием этанола.\u003Cbr\u003EПациентам с почечной недостаточностью необходимо проконсультироваться с врачом перед применением препарата, поскольку существует риск ухудшения функционального состояния почек.\u003Cbr\u003EПациентам с гипертонией, в том числе в анамнезе и/или хронической сердечной недостаточностью, необходимо проконсультироваться с врачом перед применением препарата, поскольку препарат может вызывать задержку жидкости, повышение артериального давления и отеки.\u003Cbr\u003EПациентам с неконтролируемой артериальной гипертензией, застойной сердечной недостаточностью II-III класса по NYHA, ишемической болезнью сердца, заболеваниями периферических артерий и/или цереброваскулярными заболеваниями назначать ибупрофен следует только после тщательной оценки соотношения польза-риск, при этом следует избегать применения высоких доз ибупрофена (≥2400 мг/сутки).\u003Cbr\u003EПрименение НПВП у пациентов с ветряной оспой может быть связано с повышенным риском развития тяжелых гнойных осложнений инфекционно¬воспалительных заболеваний кожи и подкожно-жировой клетчатки (например, некротизирующего фасциита). В связи с этим рекомендуется избегать применения препарата при ветряной оспе.\u003Cbr\u003EИнформация для женщин, планирующих беременность: препарат подавляет циклооксигеназу и синтез простагландинов, воздействует на овуляцию, нарушая женскую репродуктивную функцию (обратимо после отмены лечения).\u003Cbr\u003EС осторожностью:\u003Cbr\u003EПри наличии состояний, указанных в данном разделе, перед применением препарата следует обратиться к врачу.\u003Cbr\u003EОдновременный прием других НПВП, наличие в анамнезе однократного эпизода язвенной болезни желудка и двенадцатиперстной кишки или язвенного кровотечения ЖКТ; гастрит, энтерит, колит, наличие инфекции Helicobacter pylori, язвенный колит; бронхиальная астма или аллергические заболевания в стадии обострения или в анамнезе - возможно развитие бронхоспазма; системная красная волчанка или смешанное заболевание соединительной ткани (синдром Шарпа) - повышен риск асептического менингита; ветряная оспа; почечная недостаточность, в том числе при обезвоживании (клиренс креатинина менее 30-60 мл/мин), нефротический синдром, печеночная недостаточность, цирроз печени с портальной гипертензией, гипербилирубинемия, артериальная гипертензия и/или сердечная недостаточность, цереброваскулярные заболевания, заболевания крови неясной этиологии (лейкопения и анемия), тяжелые соматические заболевания, дислипидемия/гиперлипидемия, сахарный диабет, заболевания периферических артерий, курение, частое употребление алкоголя, одновременное применение лекарственных средств, которые могут увеличить риск возникновения язв или кровотечения, в частности, пероральных глюкокортикостероидов (в том числе преднизолона), антикоагулянтов (в том числе варфарина), селективных ингибиторов обратного захвата серотонина (в том числе циталопрама, флуоксетина, пароксетина, сертралина) или антиагрегантов (в том числе ацетилсалициловой кислоты, клопидогрела), беременность I-II триместр, период грудного вскармливания, пожилой возраст."},{"name":"Взаимодействие","value":"Следует избегать одновременного применения ибупрофена со следующими лекарственными средствами:\u003Cbr /\u003EАцетилсапщиловая\tкислота:\tза\tисключением\tнизких \tдоз\u003Cbr /\u003Eацетилсалициловой кислоты (не более 75 мг в сутки), назначенных врачом, поскольку совместное применение может повысить риск возникновения побочных эффектов. При одновременном применении ибупрофен снижает противовоспалительное и антиагрегантное действие ацетилсалициловой кислоты (возможно повышение частоты развития острой коронарной недостаточности у пациентов, получающих в качестве антиагрегантного средства малые дозы ацетилсалициловой кислоты, после начала приема ибупрофена).\u003Cbr /\u003E Другие НПВП, в частности, селективные ингибиторы ЦОГ-2: следует избегать одновременного применения двух и более препаратов из группы НПВП из-за возможного увеличения риска возникновения побочных эффектов.\u003Cbr /\u003EС осторожностью применять одновременно со следующими лекарственными средствами:\u003Cbr /\u003EАнтикоагулянты и тромболитические препараты: НПВП могут усиливать эффект антикоагулянтов, в частности, варфарина и тромболитических препаратов.\u003Cbr /\u003EАнтигипертензивные средства (ингибиторы АПФ и антагонисты ангиотензина II) и Диуретики.• НПВП могут снижать эффективность препаратов этих групп. У некоторых пациентов с нарушением почечной функции (например, у пациентов с обезвоживанием или у пациентов пожилого возраста с нарушением почечной функции) одновременное назначение ингибиторов АПФ или антагонистов ангиотензина П и средств, ингибирующих циклооксигеназу, может привести к ухудшению почечной функции, включая развитие острой почечной недостаточности (обычно обратимой). Эти взаимодействия следует учитывать у пациентов, принимающих коксибы одновременно с ингибиторами АПФ или антагонистами ангиотензина П. В связи с этим совместное применение вышеуказанных средств следует назначать с осторожностью, особенно у пожилых лиц. Необходимо предотвращать обезвоживание у пациентов, а также рассмотреть возможность мониторинга почечной функции после начала такого комбинированного лечения и периодически — в дальнейшем. Диуретики и ингибиторы АПФ могут повышать нефротоксичность НПВП. ГлюкокортикостероиДы: повышенный риск образования язв )ККТ и желудочно-кишечного кровотечения.\u003Cbr /\u003EАнтиагреганты и селективные ингибиторы обратного захвата серотонина: повышенный риск возникновения желудочно-кишечного кровотечения.\u003Cbr /\u003EСердечные гликозиДы: одновременное назначение НПВП и сердечных гликозидов может привести к усугублению сердечной недостаточности, снижению скорости клубочковой фильтрации и увеличению концентрации сердечных гликозидов в плазме крови.\u003Cbr /\u003EПрепараты лития: существуют данные о вероятности увеличения концентрации лития в плазме крови на фоне применения НПВП.\u003Cbr /\u003EМетотрексат: существуют данные о вероятности увеличения концентрации метотрексата в плазме крови на фоне применения НПВП. Цикчоспорин.• увеличение риска нефротоксичности при одновременном назначении НПВП и циклоспорина.\u003Cbr /\u003EМифепристон.• прием НПВП следует начать не ранее, чем через 8-12 дней после приема мифепристона, поскольку НПВП могут снижать эффективность мифепристона.\u003Cbr /\u003EТакролимус: при одновременном назначении НПВП и такролимуса возможно увеличение риска нефротоксичности.\u003Cbr /\u003EЗиДовуДин: одновременное применение НПВП и зидовудина может привести к повышению гематотоксичности. Имеются данные о повышенном риске возникновения гемартроза и гематом у ВИЧ-положительных пациентов с гемофилией, получавших совместное лечение зидовудином и ибупрофеном.\u003Cbr /\u003EАнтибиотики ХИнОл0н0ВОГО ряда: у пациентов, получающих совместное лечение НПВП и антибиотиками хинолонового ряда, возможно увеличение риска возникновения судорог.\u003Cbr /\u003EМиелотоксические препараты: усиление гематотоксичности.\u003Cbr /\u003EЦефаманДол, цефоперазон, цефотетан, вальпроевая кислота, пликамицин: увеличение частоты развития гипопротромбинемии.\u003Cbr /\u003EЛекарственные средства, блокирующие канальцевую секрецию: снижение выведения и повышение плазменной концентрации ибупрофена.\u003Cbr /\u003EИнДукторы микросомального окисления (фенитоин, этанол, барбитураты, рифампицин, фенилбутазон, трициклические антидепрессанты):\u003Cbr /\u003Eувеличение продукции гидроксилированных активных метаболитов, увеличение риска развития тяжелых интоксикаций.\u003Cbr /\u003EИнгибиторы\tмикросомального\tОКИСЛИИЯ.•\tснижение\tриска гепатотоксического действия.\u003Cbr /\u003EПероральные гипогликемические лекарственные среДства и инсулин, произвоДные сульфонилмочевины: усиление действия препаратов.\u003Cbr /\u003EАнтациды и колестирамин: снижение абсорбции.\u003Cbr /\u003EУрикозурические препараты: снижение эффективности препаратов.\u003Cbr /\u003EЭстрогены, этанол: повышенный риск возникновения побочных эффектов.\u003Cbr /\u003EКофеин: усиление анальгезирующего эффекта."},{"name":"Регистрационный номер","value":"П N016033/01"},{"name":"Дата государственной регистрации","value":"03.03.2023"},{"name":"Владелец регистрационного удостоверения","value":"Reckitt Benckiser"},{"name":"Страна бренда","value":"Великобритания"},{"name":"Страна-производитель","value":"Великобритания"},{"name":"Название препарата","value":"Нурофен"},{"name":"Срок годности","value":"1 г."}]}],"transitionId":"tr_11772069374247371583"}}}}
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    С картой  Пэй
    Цена с картой Яндекс Пэй 772 ₽ вместо 780
    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  • Коллаген для суставов капс., 120 шт.
    –21 %
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    Коллаген для суставов капс., 120 шт.

    Рейтинг товара: 4.7 из 5
    на основе 682 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 754 ₽ вместо 770
    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  • Лошадиная сила бальзам-гель Релаксирующий, 125 мл, 125 г, 1 шт., ментол, 1 уп.
    ВАМ–49 %
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    Лошадиная сила бальзам-гель Релаксирующий, 125 мл, 125 г, 1 шт., ментол, 1 уп.

    Рейтинг товара: 4.8 из 5
    на основе 264 оценки
    Цена 395 ₽ вместо 780
    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  • Крымский травник Бишофит Mg+ гель д/тела классич., 100 мл
    –40 %
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    Крымский травник Бишофит Mg+ гель д/тела классич., 100 мл

    Рейтинг товара: 4.2 из 5
    на основе 6 оценок
    Цена 435 ₽ вместо 721
    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  • Нанопласт Форте пластырь лечебный обезбол. противовосп., 40 г, 3 шт., 11 х 16 см, 1 уп.
    –1 %
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    Нанопласт Форте пластырь лечебный обезбол. противовосп., 40 г, 3 шт., 11 х 16 см, 1 уп.

    Рейтинг товара: 4.8 из 5
    на основе 57 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 264 ₽ вместо 267
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  • Глюкозамин-хондроитиновый комплекс капс., 90 шт.
    –1 %
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    Глюкозамин-хондроитиновый комплекс капс., 90 шт.

    Рейтинг товара: 4.8 из 5
    на основе 48 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 396 ₽ вместо 400
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  • Геладринк форте пор. д/приг. р-ра д/вн. приема, 420 г, апельсин
    –1 %
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    Геладринк форте пор. д/приг. р-ра д/вн. приема, 420 г, апельсин

    Рейтинг товара: 4.8 из 5
    на основе 436 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 3 748 ₽ вместо 3 786
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  • Флексотрон Соло импл. вязкоэластич. стер. для в/суст. ин., 22 мг/мл, 2 мл, 1 шт.
    –1 %
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    Флексотрон Соло импл. вязкоэластич. стер. для в/суст. ин., 22 мг/мл, 2 мл, 1 шт.

    Рейтинг товара: 4.8 из 5
    на основе 166 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 15 939 ₽ вместо 16 100
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  • Артро-Актив бальзам масляный согревающий д/нар. прим., 20 г, 1 шт., 1 уп.
    –1 %
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    Артро-Актив бальзам масляный согревающий д/нар. прим., 20 г, 1 шт., 1 уп.

    Рейтинг товара: 5 из 5
    на основе 2 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 324 ₽ вместо 327
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  • Армавискон Platinum р-р для в/суст. введ., 3%, 3 мл, 1 шт.
    –1 %
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    Армавискон Platinum р-р для в/суст. введ., 3%, 3 мл, 1 шт.

    Рейтинг товара: 4.7 из 5
    на основе 84 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 20 080 ₽ вместо 20 283
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  • Хронотрон имплантат инъекц. гель для в/суст. введ., 20 мг/мл, 2 мл, 1 шт.
    –1 %
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    Хронотрон имплантат инъекц. гель для в/суст. введ., 20 мг/мл, 2 мл, 1 шт.

    Рейтинг товара: 4.8 из 5
    на основе 73 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 9 356 ₽ вместо 9 450
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  • Артро-Актив Первая помощь капс., 36 шт.
    –1 %
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    Артро-Актив Первая помощь капс., 36 шт.

    Рейтинг товара: 4.6 из 5
    на основе 22 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 247 ₽ вместо 249
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Инструкция

Показания к применению

Нурофен Форте применяют при головной боли, мигрени, зубной боли, болезненных менструациях, невралгии, боли в спине, мышечной боли, ревматической боли и боли в суставах; а также при лихорадочном состоянии при гриппе и простудных заболеваниях.

Противопоказания

Гиперчувствительность к ибупрофену или любому из компонентов, входящих в состав препарата.
Полное или неполное сочетание бронхиальной астмы, рецидивирующего полипоза носа и околоносовых пазух, и непереносимости ацетилсалициловой кислоты или других НПВП (в том числе в анамнезе).
Эрозивно-язвенные заболевания органов желудочно-кишечного тракта (в том числе язвенная болезнь желудка и двенадцатиперстной кишки, болезнь Крона, язвенный колит) или язвенное кровотечение в активной фазе или в анамнезе (два или более подтвержденных эпизода язвенной болезни или язвенного кровотечения).
Кровотечение или перфорация язвы желудочно-кишечного тракта в анамнезе, спровоцированные применением НПВП.
Тяжелая сердечная недостаточность (класс IV по NYHA - классификация Нью-Йоркской Ассоциации кардиологов).
Тяжелая печеночная недостаточность или заболевание печени в активной фазе.
Почечная недостаточность тяжелой степени тяжести (клиренс креатинина < 30 мл/мин), подтвержденная гиперкалиемия.
Декомпенсированная сердечная недостаточность; период после проведения аортокоронарного шунтирования.
Цереброваскулярное или иное кровотечение.
Непереносимость фруктозы, глюкозо-галактозная мальабсорбция,недостаточность сахаразы-изомальтазы.
Гемофилия и другие нарушения свертываемости крови (в том числе гипокоагуляция), геморрагические диатезы.
Беременность (III триместр).
Детский возраст до 12 лет.

Способ применения и дозы

Для приема внутрь. Пациентам с повышенной чувствительностью желудка рекомендуется принимать препарат во время еды.
Только для кратковременного применения. Внимательно прочтите инструкцию перед приемом препарата.
Взрослым и детям старше 12 лет внутрь по 1 таблетке (400 мг) до З раз в сутки.
Таблетки следует запивать водой.
Интервал между приемом таблеток должен составлять не менее 6 часов.
Максимальная суточная доза составляет 1200 мг (З таблетки). Максимальная суточная доза для детей от 12 до 1 8 лет составляет 800 мг (2 таблетки).
Если при приеме препарата в течение 2-3 дней симптомы сохраняются или усиливаются, необходимо прекратить лечение и обратиться к врачу.
Полная инструкция
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Нурофен форте таб. п/о
Нурофен форте таб. п/о, 400 мг, 24 шт.
4.9
(181)
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2 вопроса
Инструкция

Цена с картой Яндекс Пэй:215 ₽

Скидка: 11%
–11 %
Вместо: 217 ₽241 ₽
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4.9
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У продавца:181 оценка·22 отзыва
У всех продавцов:391 оценка·92 отзыва
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user avatar
2 месяца назад • Светлана К. • Куплен на Маркете
Достоинства: Импорт, обезболивает,снижает температуру,убирает ломоту в мышцах и суставах. Капсулы.
Недостатки: действует отрицательно на желудок при длительном применении.
Комментарий: Хороший препарат широкого спектра действия.
user avatar
6 месяцев назад • M.A. • Куплен на Маркете
Достоинства: цена, качество, быстро помогает при головной боли
Недостатки: нет
Комментарий: Очень нравится этот Нурофен. быстро помогает при головной боли и при температуре
user avatar
2 недели назад • Владимир Негодяев • Куплен на Маркете
Достоинства: облегчает головную боль
Недостатки: действует не долго
Комментарий: в целом нормальное обезболивающее
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    Цена 772 ₽ вместо 950
  • Нанопласт Форте пластырь лечебный обезбол. противовосп., 40 г, 3 шт., 11 х 16 см, 1 уп.
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    Нанопласт Форте пластырь лечебный обезбол. противовосп., 40 г, 3 шт., 11 х 16 см, 1 уп.

    Цена 264 ₽ вместо 267
  • Глюкозамин-хондроитиновый комплекс капс., 90 шт.
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    Глюкозамин-хондроитиновый комплекс капс., 90 шт.

    Цена 396 ₽ вместо 400
  • Геладринк форте пор. д/приг. р-ра д/вн. приема, 420 г, апельсин
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    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1422663546_3/content/content/toggleWishlist":{"skuId":"455745964","productId":1422663546,"offerId":"Fj27OPRbpfuTxJvgrbRwCw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQiv+0s8qW5PsYEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCPq+sKYFEKzDqNkBGNaAjQYg59zBBw==","sign":"IYcyIimDE+9wfGHzWo3FZOqxryMEAREdduzS1WxwRsM="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1422663546_3/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Геладринк форте пор. д/приг. р-ра д/вн. приема, 420 г, апельсин

    Цена 3 748 ₽ вместо 3 786
  • Парацетамол таб., 500 мг, 10 шт.
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    Парацетамол таб., 500 мг, 10 шт.

    Цена 11 ₽
  • Снуп спрей наз., 90 мкг/доза, 15 мл
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    Снуп спрей наз., 90 мкг/доза, 15 мл

    Цена 139 ₽ вместо 154
  • Лоперамид таб., 2 мг, 10 шт.
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    Лоперамид таб., 2 мг, 10 шт.

    Цена 28 ₽
  • Уголь активированный таб., 250 мг, 50 шт.
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    Уголь активированный таб., 250 мг, 50 шт.

    Цена 50 ₽
  • {"widgets":{"@light/BannerCurtain":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_101_8/content/content/content/bannerCurtain":{"advertisementId":2071421,"impression":"/safeclick/data=SpQw45JhDGE6zDtOdUQO_HcJB4i-wRmE0HcHl_5Egdhw8Pm8UJd_q-myMBRTxLEgSZhZKEszFieT9FQtVeNhjF-I35hAfK71akUDkkZuU-sF0LNAkmZibeZHcAk7JDqMNkCCnprh5SdusACWU9R0hp4SB6WGosVIbVL3-0GKoS4-F6tDfVoEjzLN7739Bewnw44dKyKbS5Otqo3EjWDPkAXXe5UNeQPEcikxbkd1gtcNfE--5QX3SiCJcDhK4et__8IPCOTsGUABYh4Y2Msvrl3F7A4FkCzB20zK_k6i_W7r0xcRS7zCQWhF1lLQQRQ0ivwJ_o3RKQNMKbQ7Mlo5We7wChsEnFD9L7q4B2fypa8ofz7s4jA4-qHpUnTP6q_pVP2IiBXN4fkx6mZ4h_haCfk4hcrI9Otsw6DUtXaLWU4hYwa-z23_fpqXhKQ0Vzpr01EZikvg6kw6gmgJ_VN2aPTAJKTRWatzJHo7Y4Zrr-xsFKU7tBzqR-cyz0n4jaHJomDQqFCAuZhtJKvD2dqqWjMF4pOY_JlyEKJLcl6Y13OdJnBceIASpK7yFE722y2U98pDWzNo7CqlqKEjlKCSI_bGj_vjLySTD8D8hzbe5vVYBBNXD5a6V4RAq6RxflElLpVkwhU1ptBRC_EKCHuPBI8AfFKJGLRhjxEKzoKa9jyWr9MDvh7JyT9oU3iQSJJRXuyBLIHdNNzslFDNRQbohY6klK7TZMjivh98gN8BRy1jYf7vid1CtR9r9Mgzll5SyJARZydstIK8ZWQc-y8-VLEob0Yefsv0YGWqMinSaUmbXA8hCVCMhrv36Q_nvqRaqiKPc2aaCcUtYrKTHlA047wXaOevpbLis10d-7JBGEABol91hP6YMOt5RTWBHZhDI2rQdFvY5JypZfIYJXeAAEzBZ__BrHZgXM-P7Ro-xQAvxJq3aNcWgSCGVYYEfnMXcoPnXY1qRILDZeL3fMDAEpFIWgZ0LtR54rPMfcwsaBr1u6UB7krvnuz9q5d0oj3BJGFFHEI70MYSdL6a-CtHXJgjJxbvEyOkkYQi044OsR2OeD4WW_VrDnpJBvO-xP2ey7KZF5uDhE9j1NnSZKZJgQ,,/b64e=1/sign=5b9763a35c500f76b323fbc663a53b66/keyno=MARKET_1/*"}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_101_8/content/content/content/bannerCurtain":{"name":"@light/BannerCurtain"}}}
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    Реклама
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    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  • Лошадиная сила бальзам-гель Релаксирующий, 125 мл, 125 г, 1 шт., ментол, 1 уп.
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    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:974572456_9/content/content/toggleWishlist":{"skuId":"101601801911","productId":974572456,"offerId":"3_KI8NomllUEgFM1y5hFXw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQiv+0s8qW5PsYEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIXCKiX29ADELftwb/6Ahia36MRIOfcwQc=","sign":"cLGiF+/pCBBLwc5Ze340QZwkWW2mqOEBX/lCyCAXCJQ="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:974572456_9/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Лошадиная сила бальзам-гель Релаксирующий, 125 мл, 125 г, 1 шт., ментол, 1 уп.

    Цена 395 ₽ вместо 780
  • Анальгин таб., 500 мг, 10 шт.
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    Анальгин таб., 500 мг, 10 шт.

    Цена 18 ₽
  • Бромгексин таб., 8 мг, 20 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:227843683_11/content/content/gallery":{"title":"Бромгексин таб., 8 мг, 20 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/4412310/img_id3158727532549736579.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4412310/img_id3158727532549736579.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4412310/img_id3158727532549736579.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4412310/img_id3158727532549736579.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4412310/img_id3158727532549736579.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4412310/img_id3158727532549736579.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4441046/img_id7747449286684871993.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4441046/img_id7747449286684871993.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4441046/img_id7747449286684871993.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4441046/img_id7747449286684871993.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4441046/img_id7747449286684871993.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4441046/img_id7747449286684871993.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQiv+0s8qW5PsYEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCOO80mwQteGxq/kCGI+83gcgxdjBBw==","sign":"6QfYGFgRmIVByU6NqDPHlRXfZ02IbM/z+L6gRY8N7N4="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:227843683_11/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
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    Бромгексин таб., 8 мг, 20 шт.

    Цена 48 ₽
  • Парацетамол Реневал таб., 500 мг, 10 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1874785673_12/content/content/toggleWishlist":{"skuId":"102048963821","productId":1874785673,"offerId":"uh4eyRkSonJRZNMcv4ogDA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQiv+0s8qW5PsYEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIXCInr+/0GEO253pT8AhjziMASIO3ZwQc=","sign":"gsSQP84y9Jv0pQ+JMoyX1mLa6540laTG7LGvEZCdaeg="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1874785673_12/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Парацетамол Реневал таб., 500 мг, 10 шт.

    Цена 42 ₽
  • Флексотрон Соло импл. вязкоэластич. стер. для в/суст. ин., 22 мг/мл, 2 мл, 1 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778175374_13/content/content/gallery":{"title":"Флексотрон Соло импл. вязкоэластич. стер. для в/суст. ин., 22 мг/мл, 2 мл, 1 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/4544006/img_id4573924690977915558.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4544006/img_id4573924690977915558.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4544006/img_id4573924690977915558.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4544006/img_id4573924690977915558.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4544006/img_id4573924690977915558.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4544006/img_id4573924690977915558.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/5251502/img_id7830085049915648000.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5251502/img_id7830085049915648000.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5251502/img_id7830085049915648000.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5251502/img_id7830085049915648000.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5251502/img_id7830085049915648000.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5251502/img_id7830085049915648000.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQiv+0s8qW5PsYEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCI6b888GELq15cMDGMGn2Aog59zBBw==","sign":"2kWQWCel1re92UtIvCincuBid4Xl9CjoOaEs4mxq2Hg="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778175374_13/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778175374_13/content/content/toggleWishlist":{"skuId":"947477178","productId":1778175374,"offerId":"QLOf5agZyFClTwbQmI-0bQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQiv+0s8qW5PsYEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCI6b888GELq15cMDGMGn2Aog59zBBw==","sign":"2kWQWCel1re92UtIvCincuBid4Xl9CjoOaEs4mxq2Hg="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778175374_13/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Флексотрон Соло импл. вязкоэластич. стер. для в/суст. ин., 22 мг/мл, 2 мл, 1 шт.

    Цена 15 939 ₽ вместо 16 100
  • Смекта пор. д/приг. сусп. д/вн. приема, 3 г, 20 шт., ваниль
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    Смекта пор. д/приг. сусп. д/вн. приема, 3 г, 20 шт., ваниль

    Цена 202 ₽ вместо 247
  • Артро-Актив бальзам масляный согревающий д/нар. прим., 20 г, 1 шт., 1 уп.
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    Артро-Актив бальзам масляный согревающий д/нар. прим., 20 г, 1 шт., 1 уп.

    Цена 324 ₽ вместо 327
  • Армавискон Platinum р-р для в/суст. введ., 3%, 3 мл, 1 шт.
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    Армавискон Platinum р-р для в/суст. введ., 3%, 3 мл, 1 шт.

    Цена 20 080 ₽ вместо 20 283
  • Стрепсилс б/сахара таб. д/рассас., 24 шт., лимон
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    Стрепсилс б/сахара таб. д/рассас., 24 шт., лимон

    Цена 258 ₽ вместо 261
  • Коллаген для суставов капс., 120 шт.
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    Коллаген для суставов капс., 120 шт.

    Цена 754 ₽ вместо 950
  • Цитрамон П таб., 30 шт.
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    Цитрамон П таб., 30 шт.

    Цена 95 ₽ вместо 96
  • Хронотрон имплантат инъекц. гель для в/суст. введ., 20 мг/мл, 2 мл, 1 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778175275_20/content/content/toggleWishlist":{"skuId":"831564747","productId":1778175275,"offerId":"DwKsiI_3skuV5jS1zYZNdw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQiv+0s8qW5PsYEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCKua888GEMvXwowDGIqlugQg59zBBw==","sign":"Hx33hGTNIt78umTMFS4Zh+YzWpeq1rOvSgVmIRB25i0="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778175275_20/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Хронотрон имплантат инъекц. гель для в/суст. введ., 20 мг/мл, 2 мл, 1 шт.

    Цена 9 356 ₽ вместо 9 450
  • {"widgets":{"@light/BannerCurtain":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_102_21/content/content/content/bannerCurtain":{"advertisementId":2035861,"impression":"/safeclick/data=SpQw45JhDGE6zDtOdUQO_J50cmkcUKiPyaegz8z4RQpej0vflyBDquFP5k8MVkTamyogOiN_BFGuS3m1wMyT9a4L-XOESQQ8P850586MbzvvoLqiWhMGmslZ4hX9lZ3KA2GMtC1AH7l4Dm8ClhyWqUZZvaXIXho_yxT-SuxDGj3k4pP0t8W6i3bhfMnmGrPpMbzxSAycJCgxbIeEnH1d_9mBpP0h4UPp_Q7wMDZ8wUDIziFssizSlFIXS-MzPvH24ihvyMtWcchSrsQuLNt2rhGsg8_Ob2Va_tgQUgiHUDJic5XVoAcWz23J-6skUD7CBasSl4OVGA4aGyXj3aphVsOwQHUJ88VsF-fkpE_WcIHQnTSlK5IhW-8ghwWwPMKGtSFoWqINl6rYlFoyErCPp7nIJ6F6nJUS1isMGWoJPzKV5QCtKTNxFdQg6f6aUZkGJPbbEpqRcB0SnHKaZrStgpCS3vTM1xjEfdkGlmnDiTgffmVyeadnOSwut_Ex-EzZ_fZrqe3sm4otvFPsasGOrHoGFWhD1oWKYPLpekdgJ0GQV64ZrUWzWUx1D8Q7uATBlfxWzgsycjOhM2_ckkMIEFU3WRVvkAHBfe8xPondnbW5Vp52mFY7f9sNZ3h_-7PNvgg_9FCdubXrwaMSA5bCIULiS6Wy9c2ieptJnOstB_cvNLdGU-PB5OCAXig8jVcJri9fQnFF6I1Z23zw4LagCSWUznLzpnHwJDXl5X7D_9MjNVn867N8630anoT-nCeQrkwYwbMPaR6L5yTY11nLA8Ewm6V3UcofVsxUf2OrivZ2rWR1bUy5w6L-L2KLOGqMvQJNL2SEzJnDwcsKpyrdyDeA7nN3Ip7vjX-Vr5WSsQ-NDiw-s1YGQ-Jpcw3-LhvEldKWI4yx7G9-Sd6AzBurcv2F8SFyv1jniWeKqAO2uR58ME266ETKRqZg-A-P50Twql342z6B6XaksJAuGt4ZyAyWXtDGiCJbbrtLoOhzOO2mmtjhLjoqCHJNoqvlFuG6sUtR73UrOmv4YNBnn2NMZI5_KDSJr2TLl_0uxwm7n10Wpnl34nAWvWQD34S2Vg87ciPvnyTm_c5ly4yypkBgjHnPm2cHzzUR/b64e=1/sign=ee3fefdc959ec032e0dbad77d936ebd8/keyno=MARKET_1/*"}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_102_21/content/content/content/bannerCurtain":{"name":"@light/BannerCurtain"}}}
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    Реклама
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  • Артро-Актив Первая помощь капс., 36 шт.
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    Артро-Актив Первая помощь капс., 36 шт.

    Цена 247 ₽ вместо 249
  • Крымский травник Бишофит Mg+ гель д/тела классич., 100 мл
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    Крымский травник Бишофит Mg+ гель д/тела классич., 100 мл

    Цена 435 ₽ вместо 721
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