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Описание

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Орсотен Слим капс., 60 мг, 42 шт.

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4.7
(26)
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Количество штук в упаковке, шт.: 42

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Коротко о товаре

Артикул Маркета
3176284087
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
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Применяется только в сочетании с умеренно гипокалорийной диетой, содержащей не более 30 % суточной калорийности в виде жиров."},{"name":"Противопоказания","value":"-повышенная чувствительность к орлистату или к любому из компонентов препарата;\u003Cbr\u003E- синдром хронической мальабсорбции;\u003Cbr\u003E- холестаз;\u003Cbr\u003E- одновременное применение циклоспорина;\u003Cbr\u003E- одновременное применение непрямых антикоагулянтов (варфарина);\u003Cbr\u003E- одновременное применение ситаглиптина;\u003Cbr\u003E- беременность и период грудного вскармливания;\u003Cbr\u003E- возраст до 18 лет."},{"name":"Состав","value":"На одну капсулу\u003Cbr\u003EДействующее вещество:\u003Cbr\u003EОрсотен, полуфабрикат-гранулы 112,80 мг содержит орлистата 60,00 мг [Вспомогательное вещество полуфабриката-гранул: целлюлоза микрокристаллическая 52,80 мг];\u003Cbr\u003EВспомогательные вещества:\u003Cbr\u003EЦеллюлоза микрокристаллическая 22,20 мг\u003Cbr\u003EСостав твердых желатиновых капсул:\u003Cbr\u003EКорпус: титана диоксид (Е171) 0,58 мг, желатин 28,22 мг\u003Cbr\u003EКрышечка: титана диоксид (Е171) 0,19 мг, желатин 18,97 мг, краситель железа оксид желтый (Е172) 0,04 мг."},{"name":"Действующее вещество","value":"Орлистат","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["27144131:28710734"]}}},{"name":"Способ применения и дозы","value":"Для взрослых пациентов рекомендованная доза препарата Орсотен слим составляет 60 мг (1 капсула) 3 раза в день с каждым основным приемом пищи в сочетании с умеренно гипокалорийной диетой с низким содержанием жира. Капсулу следует принимать непосредственно перед едой, во время еды или не позже чем через 1 час после еды, запивая водой. Если приём пищи пропускают или если пища не содержит жира, то приём препарата Орсотен слим можно пропустить.\u003Cbr\u003EВ течение суток можно принимать не более 3-х капсул препарата Орсотен слим.\u003Cbr\u003EПрепарат Орсотен слим следует принимать только в рекомендуемых дозах.\u003Cbr\u003EЛечение рекомендуется проводить не более 6 месяцев. Полученные результаты снижения массы тела рекомендуется обсудить с врачом. Если после 12 недель применения препарата Орсотен слим не наблюдается снижения массы тела (то есть снижение массы тела составляет менее 5 % от исходной), необходима консультация врача для решения вопроса о продолжении приема препарата."},{"name":"Побочные действия","value":"Со стороны ЖКТ:\u003Cbr\u003Eочень часто: маслянистые выделения из прямой кишки, отхождение газов с некоторым количеством отделяемого, императивные позывы на дефекацию, стеаторея; часто: боль в животе, недержание кала, жидкий стул, учащение дефекации.\u003Cbr\u003EКак правило, указанные HP являются слабо выраженными и транзиторными. Они возникают на ранних этапах лечения (в первые 3 месяца терапии), причем у большинства пациентов было не более одного эпизода таких реакций.\u003Cbr\u003EПострегистрационные исследования\u003Cbr\u003EВ ходе пострегистрационного применения орлистата были отмечены следующие HP, частота которых неизвестна:\u003Cbr\u003EСо стороны органов кроветворения: снижение концентрации протромбина и увеличение показателя международного нормализованного отношения (МНО) в плазме крови у пациентов, принимавших орлистат одновременно с непрямыми антикоагулянтами.\u003Cbr\u003EСо стороны ЖКТ: незначительное кровотечение из прямой кишки, дивертикулит.\u003Cbr\u003EСо стороны кожи и подкожной клетчатки: буллёзная сыпь.\u003Cbr\u003EСо стороны иммунной системы: реакции гиперчувствительности, включая кожный зуд, кожную сыпь, крапивницу, ангионевротический отёк, бронхоспазм и анафилаксию.\u003Cbr\u003EСо стороны печени и желчевыводящих путей: желчнокаменная болезнь, гепатит, повышение активности \"печёночных\" трансаминаз и щелочной фосфатазы в плазме крови."},{"name":"Фармакологическое действие","value":"Орлистат является мощным специфическим ингибитором желудочно-кишечных липаз длительного действия. Он проявляет свою терапевтическую активность в просвете желудка и тонкой кишки, образуя ковалентную связь с активным сериновым участком желудочных и панкреатических липаз. Инактивированный фермент теряет возможность гидролизировать пищевые жиры (триглицериды) в абсорбируемые свободные жирные кислоты и моноглицериды. Нерасщеплённые триглицериды не всасываются, что приводит к уменьшению количества калорий, усвоенных организмом, и к снижению массы тела. Терапевтическое действие препарата осуществляется, таким образом, без всасывания в системный кровоток. По результатам клинических исследований орлистат, принимаемый ежедневно в дозе 60 мг 3 раза в день, блокирует абсорбцию примерно 25 % жиров, входящих в дневной рацион."},{"name":"Фармакологическая группа","value":"ингибиторы липазы ЖКТ"},{"name":"Форма выпуска","value":"капсулы"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"При температуре не выше 25 °С, в оригинальной упаковке.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"При применении орлистата в дозе 800 мг однократно и в дозе до 400 мг 3 раза в день ежедневно в течение 15 дней как у лиц с нормальной массой тела, так и у пациентов с ожирением, значительных HP не выявлено. При применении орлистата в дозе 240 мг 3 раза в день в течение 6 месяцев увеличения частоты дозозависимых HP не отмечено.\u003Cbr\u003EВ большинстве сообщений о случаях передозировки орлистата в пострегистрационный период указания на HP либо отсутствуют, либо они аналогичны тем, которые могут быть после приёма рекомендованных доз препарата.\u003Cbr\u003EВ случае передозировки необходима консультация врача. При значительной передозировке орлистата рекомендуется наблюдение за пациентом на протяжении 24 часов. По данным доклинических и клинических исследований системные эффекты, связанные с ингибированием липазы, как правило, быстро обратимы."},{"name":"Применение при беременности и кормлении грудью","value":"Препарат Орсотен слим не следует применять при беременности в связи с отсутствием достоверных клинических данных, подтверждающих безопасность его применения. Не установлено, проникает ли орлистат в грудное молоко, в связи с чем, применение препарата Орсотен слим в период грудного вскармливания не рекомендуется."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Препарат Орсотен слим не оказывает влияния на способность управлять транспортными средствами и механизмами."},{"name":"Особые указания","value":"Диета и физические упражнения являются неотъемлемой частью программы снижения массы тела. Рекомендуется начинать диетическую программу и физические упражнения до начала терапии препаратом Орсотен слим.\u003Cbr\u003EВо время приема препарата Орсотен слим необходимо придерживаться дробного, сбалансированного, умеренно гипокалорийного питания, с содержанием жира не более 30 % от суточной калорийности рациона (например, при рационе 2000 ккал/день потребление жира должно составлять не более 66 г/день). Следует придерживаться полученных рекомендаций по режиму питания и физической активности, как во время, так и после прекращения приема препарата.\u003Cbr\u003EПрименение препарата Орсотен слим приводит к увеличению содержания жира в кале уже спустя 24-48 часов после начала приема. После прекращения применения препарата Орсотен слим содержание жира в кале обычно возвращается к исходному уровню в течение 48-72 часов.\u003Cbr\u003EСоблюдение диеты с низким содержанием жира уменьшает вероятность возникновения HP со стороны ЖКТ.\u003Cbr\u003EПрием орлистата потенциально может ухудшать всасывание жирорастворимых витаминов (A, D, Е, К и бета-каротин). У подавляющего большинства пациентов, получавших орлистат в ходе четырехлетних клинических исследований, концентрации витаминов А, D, Е, К и бета-каротина были в пределах нормальных значений. С профилактической целью рекомендуется принимать поливитамины на ночь.\u003Cbr\u003EПоскольку потеря массы тела обычно сопровождается улучшением показателей углеводного обмена, пациенты с сахарным диабетом 2 типа перед началом терапии препаратом Орсотен слим должны проконсультироваться с врачом и, в случае необходимости скорректировать дозу гипогликемических препаратов.\u003Cbr\u003EСнижение массы тела при лечении может сопровождаться снижением артериального давления и концентрации ОХс в плазме крови. Пациентам, принимающим гипотензивные или гиполипидемические препараты, следует проконсультироваться с врачом и, в случае необходимости, провести коррекцию дозы этих лекарственных препаратов.\u003Cbr\u003EВ клинических исследованиях взаимодействия между контрацептивами для приема внутрь и орлистатом не наблюдалось. Однако орлистат может опосредованно снижать биодоступность контрацептивов для приема внутрь, что может привести к развитию нежелательной беременности. Рекомендуется применять дополнительные методы контрацепции в случае развития острой диареи.\u003Cbr\u003EПациентам, страдающим заболеваниями почек, необходимо проконсультироваться с врачом, так как возможно развитие гипероксалурии и нефропатии.\u003Cbr\u003EПациентам, принимающим амиодарон, варфарин или другие антикоагулянты для приема внутрь, также следует проконсультироваться с врачом до начала терапии орлистатом, поскольку возможны изменения показателя МНО.\u003Cbr\u003EПациентам следует прекратить прием препарата Орсотен слим и обратиться к врачу в случае появления симптомов: желтушное окрашивание склеры или кожи, кожный зуд, потемнение мочи и потеря аппетита.\u003Cbr\u003EВлияние на способность управлять трансп. ср. и мех.:\u003Cbr\u003EПрепарат Орсотен слим не оказывает влияния на способность управлять транспортными средствами и механизмами.\u003Cbr\u003E"},{"name":"Взаимодействие","value":"Циклоспорин\u003Cbr\u003EВ нескольких исследованиях но изучению лекарственного взаимодействия циклоспорина, при его одновременном применении с орлистатом, сообщается об уменьшении концентрации циклоспорина в плазме крови. Потенциально это может привести к уменьшению иммунодепрессивной эффективности последнего. Одновременное применение препарата Орсотен слим и циклоспорина противопоказано.\u003Cbr\u003EНепрямые антикоагулянты\u003Cbr\u003EПри одновременном применении варфарина или других антикоагулянтов для приема внутрь с препаратом Орсотен слим могут изменяться значения МНО.\u003Cbr\u003EЖирорастворимые витамины\u003Cbr\u003EПриём препарата Орсотен слим может потенциально ухудшить абсорбцию жирорастворимых витаминов (A, D, Е, К и бета-каротин).\u003Cbr\u003EАкарбоза\u003Cbr\u003EУчитывая отсутствие исследований, изучающих фармакокинетические взаимодействия, не рекомендуется применять препарат Орсотен слим одновременно с акарбозой.\u003Cbr\u003EАмиодарон\u003Cbr\u003EПри одновременном применении с орлистатом отмечено уменьшение концентрации амиодарона в плазме крови после однократного приёма. Клиническая значимость этого эффекта для пациентов, принимающих амиодарон, неясна. Одновременное применение препарата Орсотен слим и амиодарона возможно только по рекомендации врача. \u003Cbr\u003E\u003Cbr\u003EОтсутствие взаимодействия\u003Cbr\u003EОрлистат не взаимодействует с амитриптилином, фенитоином, флуоксетином, сибутрамином, фентермином, аторвастатином, правастатином, фибратами, бигуанидами, дигоксином, нифедипином, лозартаном и этанолом."},{"name":"Регистрационный номер","value":"ЛП-000301;\nЛП-№(000631)-(РГ-RU)"},{"name":"Дата государственной регистрации","value":"22.12.2020;\n17.03.2022"},{"name":"Владелец регистрационного удостоверения","value":"КРКА-РУС","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["34324371:35649313","7893318:16228896"]}}},{"name":"Изготовитель","value":"КРКА-РУС"},{"name":"Страна бренда","value":"Словения"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Орсотен","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-pishchevareniia","categoryId":"15756506","navnodeId":"72470","glfilters":["17796364:17852731"]}}},{"name":"Срок годности","value":"36 мес."}]}},"fullSpecsGrouped":{"16564242055438831871":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Органы и системы","value":"пищеварительная система"},{"name":"Назначение","value":"алиментарное ожирение, избыточная масса тела, похудение"},{"name":"Показания к применению","value":"Снижение избыточной массы тела у взрослых пациентов (старше 18 лет) с индексом массы тела (ИМТ) более 28 кг/м2. Применяется только в сочетании с умеренно гипокалорийной диетой, содержащей не более 30 % суточной калорийности в виде жиров."},{"name":"Противопоказания","value":"-повышенная чувствительность к орлистату или к любому из компонентов препарата;\u003Cbr\u003E- синдром хронической мальабсорбции;\u003Cbr\u003E- холестаз;\u003Cbr\u003E- одновременное применение циклоспорина;\u003Cbr\u003E- одновременное применение непрямых антикоагулянтов (варфарина);\u003Cbr\u003E- одновременное применение ситаглиптина;\u003Cbr\u003E- беременность и период грудного вскармливания;\u003Cbr\u003E- возраст до 18 лет."},{"name":"Состав","value":"На одну капсулу\u003Cbr\u003EДействующее вещество:\u003Cbr\u003EОрсотен, полуфабрикат-гранулы 112,80 мг содержит орлистата 60,00 мг [Вспомогательное вещество полуфабриката-гранул: целлюлоза микрокристаллическая 52,80 мг];\u003Cbr\u003EВспомогательные вещества:\u003Cbr\u003EЦеллюлоза микрокристаллическая 22,20 мг\u003Cbr\u003EСостав твердых желатиновых капсул:\u003Cbr\u003EКорпус: титана диоксид (Е171) 0,58 мг, желатин 28,22 мг\u003Cbr\u003EКрышечка: титана диоксид (Е171) 0,19 мг, желатин 18,97 мг, краситель железа оксид желтый (Е172) 0,04 мг."},{"name":"Действующее вещество","value":"Орлистат"},{"name":"Способ применения и дозы","value":"Для взрослых пациентов рекомендованная доза препарата Орсотен слим составляет 60 мг (1 капсула) 3 раза в день с каждым основным приемом пищи в сочетании с умеренно гипокалорийной диетой с низким содержанием жира. Капсулу следует принимать непосредственно перед едой, во время еды или не позже чем через 1 час после еды, запивая водой. Если приём пищи пропускают или если пища не содержит жира, то приём препарата Орсотен слим можно пропустить.\u003Cbr\u003EВ течение суток можно принимать не более 3-х капсул препарата Орсотен слим.\u003Cbr\u003EПрепарат Орсотен слим следует принимать только в рекомендуемых дозах.\u003Cbr\u003EЛечение рекомендуется проводить не более 6 месяцев. Полученные результаты снижения массы тела рекомендуется обсудить с врачом. Если после 12 недель применения препарата Орсотен слим не наблюдается снижения массы тела (то есть снижение массы тела составляет менее 5 % от исходной), необходима консультация врача для решения вопроса о продолжении приема препарата."},{"name":"Побочные действия","value":"Со стороны ЖКТ:\u003Cbr\u003Eочень часто: маслянистые выделения из прямой кишки, отхождение газов с некоторым количеством отделяемого, императивные позывы на дефекацию, стеаторея; часто: боль в животе, недержание кала, жидкий стул, учащение дефекации.\u003Cbr\u003EКак правило, указанные HP являются слабо выраженными и транзиторными. Они возникают на ранних этапах лечения (в первые 3 месяца терапии), причем у большинства пациентов было не более одного эпизода таких реакций.\u003Cbr\u003EПострегистрационные исследования\u003Cbr\u003EВ ходе пострегистрационного применения орлистата были отмечены следующие HP, частота которых неизвестна:\u003Cbr\u003EСо стороны органов кроветворения: снижение концентрации протромбина и увеличение показателя международного нормализованного отношения (МНО) в плазме крови у пациентов, принимавших орлистат одновременно с непрямыми антикоагулянтами.\u003Cbr\u003EСо стороны ЖКТ: незначительное кровотечение из прямой кишки, дивертикулит.\u003Cbr\u003EСо стороны кожи и подкожной клетчатки: буллёзная сыпь.\u003Cbr\u003EСо стороны иммунной системы: реакции гиперчувствительности, включая кожный зуд, кожную сыпь, крапивницу, ангионевротический отёк, бронхоспазм и анафилаксию.\u003Cbr\u003EСо стороны печени и желчевыводящих путей: желчнокаменная болезнь, гепатит, повышение активности \"печёночных\" трансаминаз и щелочной фосфатазы в плазме крови."},{"name":"Фармакологическое действие","value":"Орлистат является мощным специфическим ингибитором желудочно-кишечных липаз длительного действия. Он проявляет свою терапевтическую активность в просвете желудка и тонкой кишки, образуя ковалентную связь с активным сериновым участком желудочных и панкреатических липаз. Инактивированный фермент теряет возможность гидролизировать пищевые жиры (триглицериды) в абсорбируемые свободные жирные кислоты и моноглицериды. Нерасщеплённые триглицериды не всасываются, что приводит к уменьшению количества калорий, усвоенных организмом, и к снижению массы тела. Терапевтическое действие препарата осуществляется, таким образом, без всасывания в системный кровоток. По результатам клинических исследований орлистат, принимаемый ежедневно в дозе 60 мг 3 раза в день, блокирует абсорбцию примерно 25 % жиров, входящих в дневной рацион."},{"name":"Фармакологическая группа","value":"ингибиторы липазы ЖКТ"},{"name":"Форма выпуска","value":"капсулы"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"При температуре не выше 25 °С, в оригинальной упаковке.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"При применении орлистата в дозе 800 мг однократно и в дозе до 400 мг 3 раза в день ежедневно в течение 15 дней как у лиц с нормальной массой тела, так и у пациентов с ожирением, значительных HP не выявлено. При применении орлистата в дозе 240 мг 3 раза в день в течение 6 месяцев увеличения частоты дозозависимых HP не отмечено.\u003Cbr\u003EВ большинстве сообщений о случаях передозировки орлистата в пострегистрационный период указания на HP либо отсутствуют, либо они аналогичны тем, которые могут быть после приёма рекомендованных доз препарата.\u003Cbr\u003EВ случае передозировки необходима консультация врача. При значительной передозировке орлистата рекомендуется наблюдение за пациентом на протяжении 24 часов. По данным доклинических и клинических исследований системные эффекты, связанные с ингибированием липазы, как правило, быстро обратимы."},{"name":"Применение при беременности и кормлении грудью","value":"Препарат Орсотен слим не следует применять при беременности в связи с отсутствием достоверных клинических данных, подтверждающих безопасность его применения. Не установлено, проникает ли орлистат в грудное молоко, в связи с чем, применение препарата Орсотен слим в период грудного вскармливания не рекомендуется."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Препарат Орсотен слим не оказывает влияния на способность управлять транспортными средствами и механизмами."},{"name":"Особые указания","value":"Диета и физические упражнения являются неотъемлемой частью программы снижения массы тела. Рекомендуется начинать диетическую программу и физические упражнения до начала терапии препаратом Орсотен слим.\u003Cbr\u003EВо время приема препарата Орсотен слим необходимо придерживаться дробного, сбалансированного, умеренно гипокалорийного питания, с содержанием жира не более 30 % от суточной калорийности рациона (например, при рационе 2000 ккал/день потребление жира должно составлять не более 66 г/день). Следует придерживаться полученных рекомендаций по режиму питания и физической активности, как во время, так и после прекращения приема препарата.\u003Cbr\u003EПрименение препарата Орсотен слим приводит к увеличению содержания жира в кале уже спустя 24-48 часов после начала приема. После прекращения применения препарата Орсотен слим содержание жира в кале обычно возвращается к исходному уровню в течение 48-72 часов.\u003Cbr\u003EСоблюдение диеты с низким содержанием жира уменьшает вероятность возникновения HP со стороны ЖКТ.\u003Cbr\u003EПрием орлистата потенциально может ухудшать всасывание жирорастворимых витаминов (A, D, Е, К и бета-каротин). У подавляющего большинства пациентов, получавших орлистат в ходе четырехлетних клинических исследований, концентрации витаминов А, D, Е, К и бета-каротина были в пределах нормальных значений. С профилактической целью рекомендуется принимать поливитамины на ночь.\u003Cbr\u003EПоскольку потеря массы тела обычно сопровождается улучшением показателей углеводного обмена, пациенты с сахарным диабетом 2 типа перед началом терапии препаратом Орсотен слим должны проконсультироваться с врачом и, в случае необходимости скорректировать дозу гипогликемических препаратов.\u003Cbr\u003EСнижение массы тела при лечении может сопровождаться снижением артериального давления и концентрации ОХс в плазме крови. Пациентам, принимающим гипотензивные или гиполипидемические препараты, следует проконсультироваться с врачом и, в случае необходимости, провести коррекцию дозы этих лекарственных препаратов.\u003Cbr\u003EВ клинических исследованиях взаимодействия между контрацептивами для приема внутрь и орлистатом не наблюдалось. Однако орлистат может опосредованно снижать биодоступность контрацептивов для приема внутрь, что может привести к развитию нежелательной беременности. Рекомендуется применять дополнительные методы контрацепции в случае развития острой диареи.\u003Cbr\u003EПациентам, страдающим заболеваниями почек, необходимо проконсультироваться с врачом, так как возможно развитие гипероксалурии и нефропатии.\u003Cbr\u003EПациентам, принимающим амиодарон, варфарин или другие антикоагулянты для приема внутрь, также следует проконсультироваться с врачом до начала терапии орлистатом, поскольку возможны изменения показателя МНО.\u003Cbr\u003EПациентам следует прекратить прием препарата Орсотен слим и обратиться к врачу в случае появления симптомов: желтушное окрашивание склеры или кожи, кожный зуд, потемнение мочи и потеря аппетита.\u003Cbr\u003EВлияние на способность управлять трансп. ср. и мех.:\u003Cbr\u003EПрепарат Орсотен слим не оказывает влияния на способность управлять транспортными средствами и механизмами.\u003Cbr\u003E"},{"name":"Взаимодействие","value":"Циклоспорин\u003Cbr\u003EВ нескольких исследованиях но изучению лекарственного взаимодействия циклоспорина, при его одновременном применении с орлистатом, сообщается об уменьшении концентрации циклоспорина в плазме крови. Потенциально это может привести к уменьшению иммунодепрессивной эффективности последнего. Одновременное применение препарата Орсотен слим и циклоспорина противопоказано.\u003Cbr\u003EНепрямые антикоагулянты\u003Cbr\u003EПри одновременном применении варфарина или других антикоагулянтов для приема внутрь с препаратом Орсотен слим могут изменяться значения МНО.\u003Cbr\u003EЖирорастворимые витамины\u003Cbr\u003EПриём препарата Орсотен слим может потенциально ухудшить абсорбцию жирорастворимых витаминов (A, D, Е, К и бета-каротин).\u003Cbr\u003EАкарбоза\u003Cbr\u003EУчитывая отсутствие исследований, изучающих фармакокинетические взаимодействия, не рекомендуется применять препарат Орсотен слим одновременно с акарбозой.\u003Cbr\u003EАмиодарон\u003Cbr\u003EПри одновременном применении с орлистатом отмечено уменьшение концентрации амиодарона в плазме крови после однократного приёма. Клиническая значимость этого эффекта для пациентов, принимающих амиодарон, неясна. 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Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом

Где купить

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Цена с картой Яндекс Пэй:1 337 ₽

Скидка: 2%
–2 %
Вместо: 1 365 ₽
  • 11 июня, курьер Маркета • 99 ₽
POLZAru
Рейтинг 4.9 из 5
38Котзывов
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Ещё может подойти

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Инструкция

Показания к применению

Снижение избыточной массы тела у взрослых пациентов (старше 18 лет) с индексом массы тела (ИМТ) более 28 кг/м2. Применяется только в сочетании с умеренно гипокалорийной диетой, содержащей не более 30 % суточной калорийности в виде жиров.

Противопоказания

-повышенная чувствительность к орлистату или к любому из компонентов препарата;
- синдром хронической мальабсорбции;
- холестаз;
- одновременное применение циклоспорина;
- одновременное применение непрямых антикоагулянтов (варфарина);
- одновременное применение ситаглиптина;
- беременность и период грудного вскармливания;
- возраст до 18 лет.

Способ применения и дозы

Для взрослых пациентов рекомендованная доза препарата Орсотен слим составляет 60 мг (1 капсула) 3 раза в день с каждым основным приемом пищи в сочетании с умеренно гипокалорийной диетой с низким содержанием жира. Капсулу следует принимать непосредственно перед едой, во время еды или не позже чем через 1 час после еды, запивая водой. Если приём пищи пропускают или если пища не содержит жира, то приём препарата Орсотен слим можно пропустить.
В течение суток можно принимать не более 3-х капсул препарата Орсотен слим.
Препарат Орсотен слим следует принимать только в рекомендуемых дозах.
Лечение рекомендуется проводить не более 6 месяцев. Полученные результаты снижения массы тела рекомендуется обсудить с врачом. Если после 12 недель применения препарата Орсотен слим не наблюдается снижения массы тела (то есть снижение массы тела составляет менее 5 % от исходной), необходима консультация врача для решения вопроса о продолжении приема препарата.
Полная инструкция
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Орсотен Слим капс.
Орсотен Слим капс., 60 мг, 42 шт.
4.7
(26)
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3 вопроса
Инструкция

Цена с картой Яндекс Пэй:1 337 ₽

Скидка: 2%
–2 %
Вместо: 1 365 ₽
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4.7
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У продавца:26 оценок·5 отзывов
У всех продавцов:201 оценка·40 отзывов
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user avatar
Месяц назад • Ася • Куплен на Маркете
Достоинства: нравится данный препарат
Недостатки: нету упакован хорошо.
Комментарий: рекомендую к покупке
user avatar
Год назад • елена н. • Куплен на Маркете
Комментарий: прошла курс ушло 4 кг буду брать еще
user avatar
2 года назад • Анна Ш. • Куплен на Маркете
Достоинства: Помогает
Комментарий: Лучше жирное не есть с этими капсулами
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    Листата мини таб. п/о плен., 60 мг, 20 шт.

    Цена 708 ₽ вместо 715
  • Голдлайн плюс капс., 10 мг+158,5 мг, 10 шт.
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    Голдлайн плюс капс., 10 мг+158,5 мг, 10 шт.

    Цена 702 ₽
  • Орсотен капс., 120 мг, 21 шт.
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    Орсотен капс., 120 мг, 21 шт.

    Цена 1 035 ₽
  • Листата таб. п/о плен., 120 мг, 20 шт.
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    Листата таб. п/о плен., 120 мг, 20 шт.

    Цена 1 096 ₽
  • Орлистат-акрихин капс., 120 мг, 84 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778170956_5/content/content/gallery":{"title":"Орлистат-акрихин капс., 120 мг, 84 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/5207439/img_id3912089758593840517.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5207439/img_id3912089758593840517.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5207439/img_id3912089758593840517.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5207439/img_id3912089758593840517.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5207439/img_id3912089758593840517.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5207439/img_id3912089758593840517.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/931379/img_id7026875332700593359.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/931379/img_id7026875332700593359.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/931379/img_id7026875332700593359.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/931379/img_id7026875332700593359.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/931379/img_id7026875332700593359.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/931379/img_id7026875332700593359.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQj+LYwe6634BJEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIVCMz48s8GEP3r32wYud3QByDa2cEH","sign":"p5oqVz+dnXzflXFMXB+xU1k0w+Kse3yQL6dxbHtX6vc="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778170956_5/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
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    Орлистат-акрихин капс., 120 мг, 84 шт.

    Цена 3 185 ₽
  • Vitamin D3, 10000 МЕ, 120 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1775010076_6/content/content/gallery":{"title":"Vitamin D3, 10000 МЕ, 120 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/7396071/img_id6667521112210008179.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/7396071/img_id6667521112210008179.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/7396071/img_id6667521112210008179.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/7396071/img_id6667521112210008179.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/7396071/img_id6667521112210008179.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/7396071/img_id6667521112210008179.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/6374009/img_id6098485571755441371.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/6374009/img_id6098485571755441371.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/6374009/img_id6098485571755441371.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/6374009/img_id6098485571755441371.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/6374009/img_id6098485571755441371.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/6374009/img_id6098485571755441371.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/5253277/img_id1387298086521335854.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5253277/img_id1387298086521335854.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5253277/img_id1387298086521335854.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5253277/img_id1387298086521335854.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5253277/img_id1387298086521335854.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5253277/img_id1387298086521335854.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4219717/img_id9080607274005750643.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4219717/img_id9080607274005750643.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4219717/img_id9080607274005750643.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4219717/img_id9080607274005750643.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4219717/img_id9080607274005750643.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4219717/img_id9080607274005750643.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQj+LYwe6634BJEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCJyCss4GELC+37H7AhjxybYEIJnDBQ==","sign":"DNGzJ8TutTGqXPpsLo9rvZlnAFV4xctGBTJ2XRaT2Qw="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1775010076_6/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1775010076_6/content/content/toggleWishlist":{"skuId":"101841362736","productId":1775010076,"offerId":"n5AURMrokESoQFjz9hckVw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQj+LYwe6634BJEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCJyCss4GELC+37H7AhjxybYEIJnDBQ==","sign":"DNGzJ8TutTGqXPpsLo9rvZlnAFV4xctGBTJ2XRaT2Qw="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1775010076_6/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Vitamin D3, 10000 МЕ, 120 шт.

    Цена 1 209 ₽ вместо 2 455
  • ЛимфоТранзит концентрат напитка фл., 100 мл
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1780857920_7/content/content/gallery":{"title":"ЛимфоТранзит концентрат напитка фл., 100 мл","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/4489193/img_id4629792869941954388.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4489193/img_id4629792869941954388.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4489193/img_id4629792869941954388.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4489193/img_id4629792869941954388.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4489193/img_id4629792869941954388.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4489193/img_id4629792869941954388.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4880383/img_id7613492906357521498.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4880383/img_id7613492906357521498.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4880383/img_id7613492906357521498.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4880383/img_id7613492906357521498.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4880383/img_id7613492906357521498.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4880383/img_id7613492906357521498.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4012265/img_id719118711323658415.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4012265/img_id719118711323658415.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4012265/img_id719118711323658415.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4012265/img_id719118711323658415.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4012265/img_id719118711323658415.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4012265/img_id719118711323658415.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4322107/img_id1313108835997666733.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4322107/img_id1313108835997666733.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4322107/img_id1313108835997666733.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4322107/img_id1313108835997666733.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4322107/img_id1313108835997666733.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4322107/img_id1313108835997666733.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQj+LYwe6634BJEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCMD4ltEGEI2Jl7wCGNW7oQYg19zBBw==","sign":"Nq2cIxG142feZtekGp3RssoEcWA/YLVzXK2oqq+r16g="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1780857920_7/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1780857920_7/content/content/toggleWishlist":{"skuId":"663078029","productId":1780857920,"offerId":"sfF41jLd_lfJnq7MPes0zw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQj+LYwe6634BJEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCMD4ltEGEI2Jl7wCGNW7oQYg19zBBw==","sign":"Nq2cIxG142feZtekGp3RssoEcWA/YLVzXK2oqq+r16g="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1780857920_7/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    ЛимфоТранзит концентрат напитка фл., 100 мл

    Цена 332 ₽ вместо 390
  • Реклама
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  • Орлистат-акрихин капс., 120 мг, 42 шт.
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    Орлистат-акрихин капс., 120 мг, 42 шт.

    Цена 1 689 ₽
  • Редуксин капс., 10 мг+158.5 мг, 30 шт.
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    Редуксин капс., 10 мг+158.5 мг, 30 шт.

    Цена 2 749 ₽
  • Ксеникал капс., 120 мг, 21 шт.
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    Ксеникал капс., 120 мг, 21 шт.

    Цена 1 012 ₽
  • Редуксин Форте таб. п/о плен., 850 мг+10 мг, 30 шт.
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    Редуксин Форте таб. п/о плен., 850 мг+10 мг, 30 шт.

    Цена 2 679 ₽
  • Жидкий пластырь Fixplast c пантенолом, 60 мл
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    Жидкий пластырь Fixplast c пантенолом, 60 мл

    Цена 355 ₽ вместо 399
  • Редуксин лайт капс., 30 шт.
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    Редуксин лайт капс., 30 шт.

    Цена 2 164 ₽ вместо 3 313
  • Флексотрон Соло импл. вязкоэластич. стер. для в/суст. ин., 22 мг/мл, 2 мл, 1 шт.
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    Флексотрон Соло импл. вязкоэластич. стер. для в/суст. ин., 22 мг/мл, 2 мл, 1 шт.

    Цена 15 939 ₽ вместо 16 100
  • Вата стерильная хирургическая 100 г
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    Вата стерильная хирургическая 100 г

    Цена 173 ₽ вместо 198
  • Пастилки California Gold Nutrition Vitamin D3 gummies со вкусом фруктов и ягод, 280 г, 90 шт.
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    Пастилки California Gold Nutrition Vitamin D3 gummies со вкусом фруктов и ягод, 280 г, 90 шт.

    Цена 421 ₽ вместо 425
  • Nutridrink (Nutricia) Compact Protein, готовое к употреблению, 500 мл, 500 г, банан, 4 шт.
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    Nutridrink (Nutricia) Compact Protein, готовое к употреблению, 500 мл, 500 г, банан, 4 шт.

    Цена 1 267 ₽ вместо 1 280
  • Nutrison (Nutricia) Эдванс, сухая смесь, 332 мл, 322 г, нейтральный
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:253165360_19/content/content/toggleWishlist":{"skuId":"100498297658","productId":253165360,"offerId":"BF6ye9_qTCUDA2fU8iH5RQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQj+LYwe6634BJEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCLD+23gQuqapsfYCGOmR2gcgmI/VBw==","sign":"QvW9Nw8c4Rng02vVkWKjjx80I9rtWaZNh+CWeDwjmnE="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:253165360_19/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Nutrison (Nutricia) Эдванс, сухая смесь, 332 мл, 322 г, нейтральный

    Цена 1 064 ₽ вместо 1 075
  • Эвалар Чай Эвалар БИО при повышенном содержании мочевой кислоты, 20 фильтр-пакетов
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    Эвалар Чай Эвалар БИО при повышенном содержании мочевой кислоты, 20 фильтр-пакетов

    Цена 194 ₽ вместо 224
  • Реклама
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  • Салфетка с нашатырем для стимуляции дыхания 3х6, 20 шт
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    Салфетка с нашатырем для стимуляции дыхания 3х6, 20 шт

    Цена 199 ₽ вместо 250
  • Магне B6 таб. п/о, 100 шт.
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    Магне B6 таб. п/о, 100 шт.

    Цена 1 199 ₽ вместо 1 344
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