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Описание

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Ортофен таб. п/о плен. кш/раств., 25 мг, 20 шт.

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5.0
(11)
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Коротко о товаре

Артикул Маркета
3123170278
Тип препарата
Назначение
Действующее вещество
Возраст
от 6 лет
Инструкция
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Болевые синдромы со стороны позвоночника (люмбаго, ишиалгия, оссалгия, невралгия, миалгия, артралгия, радикулит). Посттравматический и послеоперационный болевой синдром, сопровождающийся воспалением, например, в стоматологии и ортопедии. Альгодисменорея; воспалительные процессы в малом тазу, в том числе аднексит. Изолированная лихорадка не является показанием к применению препарата. Препарат предназначен для симптоматической терапии, уменьшения боли и воспаления на момент применения, на прогрессирование заболевания не влияет."},{"name":"Противопоказания","value":"Обострение язвенной болезни желудка и двенадцатиперстной кишки, кровотечения из органов желудочно-кишечного тракта (ЖКТ), перфорация органов ЖКТ. Повышенная чувствительность к диклофенаку и любым другим компонентам препарата. III триместр беременности. Как и другие нестероидные противовоспалительные препараты (НПВП), препарат Ортофен противопоказан пациентам с полным или неполным сочетанием бронхиальной астмы, рецидивирующего полипоза носа и околоносовых пазух и непереносимости ацетилсалициловой кислоты или других НПВП (в том числе в анамнезе). Нарушение функции печени тяжелой степени тяжести, почечная недостаточность (СКФ менее 15 мл/мин/1,73 м2), хроническая сердечная недостаточность (II-IV функциональный класс по классификации NYHA). Ишемическая болезнь сердца. Цереброваскулярные заболевания, заболевания периферических артерий. Повышенный риск артериальных тромбозов и тромбоэмболий, неконтролируемая артериальная гипертензия. Состояния, сопровождающиеся риском развития кровотечений. Подтвержденная гиперкалиемия. Аортокоронарное шунтирование (периоперационный период). Воспалительные заболевания кишечника (болезнь Крона, язвенный колит) в фазе обострения. Активные заболевания печени. Период грудного вскармливания. Наследственная тяжелая непереносимость лактозы, недостаточность лактазы и глюкозо-галактозная мальабсорбция (т.к. лекарственная форма содержит лактозу). Не рекомендуется применение препарата Ортофен таблетки кишечнорастворимые, покрытые пленочной оболочкой, 25 мг у детей в возрасте до 6 лет."},{"name":"Состав","value":"1 таблетка содержит:\u003Cbr\u003EДействующее вещество: диклофенак натрия (диклофенак) - 25,0 мг.\u003Cbr\u003EВспомогательные вещества: лактозы моногидрат, сахароза, крахмал картофельный, повидон (поливинилпирролидон низкомолекулярный, пласдон К-17), кальция стеарат.\u003Cbr\u003EВспомогательные вещества оболочки: ацетилфталилцеллюлоза, титана диоксид, касторовое масло, вазелиновое масло, тропеолин 0."},{"name":"Действующее вещество","value":"Диклофенак","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["27144131:28710287"]}}},{"name":"Способ применения и дозы","value":"Доза препарата подбирается индивидуально, при этом с целью снижения риска развития побочных эффектов рекомендуется применение минимальной эффективной дозы, по возможности, с максимально коротким периодом лечения в соответствии с целью лечения и состоянием пациента. Таблетки следует проглатывать целиком, запивая жидкостью, желательно до еды. Нельзя делить или разжевывать таблетки."},{"name":"Побочные действия","value":"Нарушения со стороны крови и лимфатической системы: очень редко - тромбоцитопения, лейкопения, гемолитическая анемия, апластическая анемия, агранулоцитоз.\u003Cbr\u003EНарушения со стороны иммунной системы: редко - гиперчувствительность, анафилактические/анафилактоидные реакции, включая снижение артериального давления (АД) и шок; очень редко - ангионевротический отек (включая отек лица).\u003Cbr\u003EНарушения психики: очень редко - дезориентация, депрессия, бессонница, кошмарные сновидения, раздражительность, психические нарушения.\u003Cbr\u003EНарушения со стороны нервной системы: часто - головная боль, головокружение; редко - сонливость; очень редко - нарушения чувствительности, включая парестезии, расстройства памяти, тремор, судороги, ощущение тревоги, острые нарушения мозгового кровообращения, асептический менингит.\u003Cbr\u003EНарушения со стороны органа зрения: очень редко - нарушение зрения (затуманивание зрения), диплопия.\u003Cbr\u003EНарушения со стороны органа слуха и лабиринтные нарушения: часто - вертиго; очень редко - нарушения слуха, шум в ушах.\u003Cbr\u003EНарушения со стороны сердца: нечасто - инфаркт миокарда, сердечная недостаточность, ощущение сердцебиения, боль в груди.\u003Cbr\u003EНарушения со стороны сосудов: очень редко - повышение АД, васкулит.\u003Cbr\u003EНарушения со стороны дыхательной системы, органов грудной клетки и средостения: редко - бронхиальная астма (включая одышку); очень редко - пневмонит.\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта: часто - абдоминальная боль, тошнота, рвота, диарея, диспепсия, метеоризм, снижение аппетита; редко - гастрит, желудочно-кишечное кровотечение, рвота кровью, мелена, диарея с примесью крови, язвы желудка и кишечника (с или без кровотечения, стеноза или перфорации, с возможным развитием перитонита); очень редко - стоматит, глоссит, повреждения пищевода, возникновение диафрагмоподобных стриктур в кишечнике, колит (неспецифический геморрагический колит, ишемический колит, обострение язвенного колита или болезни Крона), запор, панкреатит.\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей: часто - повышение активности аминотрансфераз в плазме крови; редко - гепатит, желтуха, нарушения функции печени; очень редко - молниеносный гепатит, некроз печени, печеночная недостаточность.\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей: часто - кожная сыпь; редко - крапивница; очень редко - буллезный дерматит, экзема, эритема, многоформная эритема, синдром Стивенса-Джонсона, синдром Лайелла (токсический эпидермальный некролиз), эксфолиативный дерматит, зуд, алопеция, реакции фоточувствительности, пурпура, пурпура Шенлейна-Геноха.\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей: очень редко - острое поражение почек (острая почечная недостаточность), гематурия, протеинурия, тубулоинтерстициальный нефрит, нефротический синдром, папиллярный некроз.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения: редко - отеки.\u003Cbr\u003EНарушения со стороны сердечно-сосудистой системы\u003Cbr\u003EДанные клинических исследований указывают на небольшое увеличение риска развития сердечно-сосудистых тромботических осложнений (например, инфаркта миокарда), особенно при длительном применении диклофенака в высоких дозах (суточная доза более 150 мг).\u003Cbr\u003EЗрительные нарушения\u003Cbr\u003EЗрительные расстройства, такие как нарушение зрения, затуманивание зрения или диплопия, по-видимому, являются класс-эффектами НПВП, и обратимы после прекращения применения. Возможным механизмом развития таких расстройств является ингибирование синтеза простагландинов и других сопутствующих веществ, что изменяет регуляцию кровотока в сетчатке, которое проявляется потенциальными зрительными расстройствами. При развитии таких симптомов на фоне терапии диклофенаком следует рассмотреть возможность офтальмологического обследования для исключения каких-либо других причин.\u003Cbr\u003EЕсли любые из указанных в инструкции побочных эффектов усугубляются, или Вы заметили любые другие побочные эффекты, не указанные в инструкции, сообщите об этом врачу."},{"name":"Фармакологическое действие","value":"Препарат содержит диклофенак натрия, вещество нестероидной структуры, оказывающее выраженное противовоспалительное, анальгезирующее и жаропонижающее действие. Основным механизмом действия диклофенака, установленным в исследованиях, считается торможение биосинтеза простагландинов. Простагландины играют важную роль в генезе воспаления, боли и лихорадки. In vitro диклофенак натрия в концентрациях, эквивалентных тем, которые достигаются при применении у человека, не подавляет биосинтез протеогликанов хрящевой ткани. При ревматических заболеваниях противовоспалительные и анальгезирующие свойства препарата обеспечивают клинический эффект, характеризующийся значительным уменьшением выраженности таких проявлений, как боль в покое и при движении, утренняя скованность и припухлость суставов, а также улучшением функционального состояния. При посттравматических и послеоперационных воспалительных явлениях диклофенак быстро купирует боль (как в покое, так и при движении), уменьшает воспалительный отек и отек послеоперационной раны. При применении препарата отмечен выраженный анальгезирующий эффект при умеренной и сильной боли неревматического происхождения. Также установлено, что диклофенак способен уменьшать болевые ощущения и снижать кровопотерю при первичной дисменорее."},{"name":"Фармакологическая группа","value":"нестероидный противовоспалительный препарат (НПВП)"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 6 лет"},{"name":"Условия хранения","value":"В защищенном от света месте, при температуре не выше 25 °С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы: рвота, желудочно-кишечное кровотечение, диарея, головокружение, шум в ушах, судороги. В случае значительного отравления, возможно развитие острой почечной недостаточности и поражения печени. Лечение: поддерживающее и симптоматическое лечение показано при таких осложнениях как снижение АД, почечная недостаточность, судороги, нарушения со стороны ЖКТ и угнетение дыхания. Форсированный диурез, гемодиализ или гемоперфузия для выведения НПВП, в т.ч. диклофенака, из организма неэффективны, так как действующие вещества этих препаратов в значительной степени связываются с белками плазмы и подвергаются интенсивному метаболизму. В случае жизнеугрожающей передозировки при приеме препарата внутрь в целях скорейшего предотвращения всасывания диклофенака следует провести промывание желудка и назначить активированный уголь."},{"name":"Применение при беременности и кормлении грудью","value":"Недостаточно данных о безопасности применения диклофенака у беременных женщин, в связи с чем применять препарат Ортофен в I и II триместрах беременности следует только в тех случаях, когда ожидаемая польза для матери превышает потенциальный риск для плода. Препарат, как и другие НПВП (ингибиторы синтеза простагландинов), противопоказан в последние 3 месяца беременности (возможно подавление сократительной способности матки, нарушение функции почек у плода с последующим маловодием (олигогидроамнион) и/или преждевременное закрытие артериального протока у плода). Несмотря на то, что препарат Ортофен, как и другие НПВП, проникает в грудное молоко в малом количестве, препарат не следует применять в период грудного вскармливания во избежание нежелательного влияния на ребенка. При необходимости применения препарата у женщины в этот период грудное вскармливание прекращают. Поскольку препарат Ортофен, как и другие НПВП, может оказывать отрицательное действие на фертильность, женщинам, планирующим беременность, не рекомендуется принимать препарат. У пациенток, проходящих обследование и лечение по поводу бесплодия, препарат следует отменить."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Пациентам, у которых на фоне применения препарата Ортофен возникают зрительные нарушения, головокружение, сонливость, вертиго или другие нарушения со стороны центральной нервной системы, не следует управлять транспортными средствами и работать с механизмами."},{"name":"Особые указания","value":"Поражение ЖКТ\u003Cbr\u003EПри применении диклофенака, как и других НПВП, отмечались такие явления, как кровотечение или изъязвление/перфорация органов ЖКТ, в ряде случаев со смертельным исходом. Данные явления могут возникнуть в любое время при применении данных препаратов с или без предшествующих симптомов или серьезных заболеваний органов ЖКТ в анамнезе.\u003Cbr\u003EУ пожилых пациентов подобные осложнения могут иметь серьезные последствия. При развитии у пациентов, получающих препарат Ортофен, кровотечений или изъязвления ЖКТ препарат следует отменить.\u003Cbr\u003EДля снижения риска развития токсического действия на ЖКТ у пациентов с язвенным поражением ЖКТ, особенно осложненным кровотечением или перфорацией в анамнезе, а также у пожилых пациентов следует применять в минимальной эффективной дозе.\u003Cbr\u003EУ пациентов с повышенным риском развития желудочно-кишечных осложнений, а также у пациентов, получающих терапию низкими дозами ацетилсалициловой кислоты, на фоне терапии препаратом следует принимать гастропротекторы (ингибиторы протонной помпы или мизопростол), или другие лекарственные препараты для снижения риска нежелательного воздействия на ЖКТ.\u003Cbr\u003EПациентам с поражением ЖКТ в анамнезе, особенно пожилым, необходимо сообщать врачу обо всех абдоминальных симптомах.\u003Cbr\u003EПациенты с бронхиальной астмой\u003Cbr\u003EОбострение бронхиальной астмы (непереносимость НПВП/бронхиальная астма, провоцируемая приемом НПВП), отек Квинке и крапивница наиболее часто отмечаются у пациентов с бронхиальной астмой, сезонным аллергическим ринитом, носовыми полипами, хронической обструктивной болезнью легких или хроническими инфекционными заболеваниями дыхательных путей (особенно связанными с аллергическими риноподобными симптомами). У данной группы пациентов, а также у пациентов с аллергией на другие лекарственные препараты (кожные сыпь и зуд или крапивница) при применении препарата Ортофен следует соблюдать особую осторожность (готовность к проведению реанимационных мероприятий).\u003Cbr\u003EКожные реакции\u003Cbr\u003EТакие серьезные дерматологические реакции как эксфолиативный дерматит, синдром Стивенса-Джонсона, токсический эпидермальный некролиз, в некоторых случаях со смертельным исходом, на фоне применения диклофенака отмечались очень редко. Наибольшие риск и частота развития тяжелых дерматологических реакций отмечались в первый месяц лечения диклофенаком. При развитии у пациента, получающего препарат Ортофен, первых признаков кожной сыпи, поражений слизистых оболочек или других симптомов гиперчувствительности препарат следует отменить.\u003Cbr\u003EВ редких случаях при применении препарата Ортофен, как и других НПВП, возможно развитие анафилактических/анафилактоидных реакций у пациентов, ранее не получавших диклофенак.\u003Cbr\u003EВоздействие на печень\u003Cbr\u003EПоскольку в период применения препарата Ортофен может отмечаться повышение активности одного или нескольких \"печеночных\" ферментов, при длительной терапии препаратом в качестве меры предосторожности показан контроль функции печени. При сохранении и прогрессировании нарушений функции печени или возникновении признаков заболеваний печени или других симптомов (например, эозинофилии, сыпи и т.п.) прием препарата необходимо отменить. Следует иметь в виду, что гепатит на фоне применения препарата Ортофен может развиваться без продромальных явлений.\u003Cbr\u003EВоздействие на почки\u003Cbr\u003EНа фоне терапии препаратом рекомендуется проводить контроль функции почек у пациентов с гипертонической болезнью, нарушениями функции сердца или почек, пожилых пациентов, пациентов, принимающих диуретики или другие препараты, влияющие на функцию почек, а также у пациентов со значительным уменьшением объема внеклеточной жидкости любой этиологии, например, в период до и после массивных хирургических вмешательств. После прекращения терапии препаратом обычно отмечается нормализация показателей функции почек до исходных значений.\u003Cbr\u003EВоздействие на сердечно-сосудистую систему\u003Cbr\u003EТерапия НПВП, в том числе диклофенаком, в особенности длительная терапия и терапия с использованием высоких доз, может быть ассоциирована с небольшим возрастанием риска развития серьезных сердечно-сосудистых тромботических осложнений (включая инфаркт миокарда и инсульт).\u003Cbr\u003EУ пациентов с заболеваниями сердечно-сосудистой системы и высоким риском развития заболеваний сердечно-сосудистой системы (например, с артериальной гипертензией, гиперлипидемией, сахарным диабетом, курящих) следует применять препарат с особой осторожностью, в самой низкой эффективной дозе при минимально возможной длительности лечения, поскольку риск возникновения тромботических осложнений возрастает при увеличении дозы и продолжительности лечения.\u003Cbr\u003EПри длительной терапии (более 4 недель) суточная доза диклофенака у таких пациентов не должна превышать 100 мг. Следует периодически проводить оценку эффективности лечения и потребности пациента в симптоматической терапии, особенно в тех случаях, когда ее продолжительность составляет более 4 недель. При появлении первых симптомов тромботических нарушений (например, боли в груди, чувства нехватки воздуха, слабости, нарушения речи) пациенту следует незамедлительно обратиться за медицинской помощью.\u003Cbr\u003EВоздействие на систему кроветворения\u003Cbr\u003EПрепарат может временно ингибировать агрегацию тромбоцитов, поэтому у пациентов с нарушениями гемостаза необходимо проводить тщательный контроль соответствующих лабораторных показателей.\u003Cbr\u003EПри длительном применении препарата Ортофен рекомендуется проводить регулярные клинические анализы периферической крови.\u003Cbr\u003EМаскирование признаков инфекционного процесса\u003Cbr\u003EПротивовоспалительное действие препарата Ортофен может затруднять диагностику инфекционных процессов.\u003Cbr\u003EПрименение одновременно с другими НПВП\u003Cbr\u003EНе следует применять препарат одновременно с другими НПВП, включая селективные ингибиторы ЦОГ-2 из-за риска нежелательных явлений."},{"name":"Взаимодействие","value":"Выявленные взаимодействия\u003Cbr\u003EИнгибиторы изофермента CYP2C9\u003Cbr\u003EСледует соблюдать осторожность при одновременном применении диклофенака и ингибиторов изофермента CYP2C9 (таких как вориконазол) из-за возможного увеличения концентрации диклофенака в сыворотке крови и его экспозиции.\u003Cbr\u003EЛитий, дигоксин\u003Cbr\u003EДиклофенак может повышать концентрации лития и дигоксина в плазме крови. Рекомендуется контролировать содержания лития и концентрации дигоксина в сыворотке крови.\u003Cbr\u003EДиуретические и гипотензивные средства\u003Cbr\u003EПри одновременном применении с диуретиками и гипотензивными препаратами (например, бета-адреноблокаторами, ингибиторами ангиотензин-превращающего фермента - АПФ) диклофенак может снижать их гипотензивное действие. В связи с вышесказанным у пациентов, особенно пожилого возраста, при одновременном применении диклофенака и диуретиков или гипотензивных средств следует регулярно измерять АД, контролировать функцию почек и степень гидратации (вследствие повышения риска нефротоксичности).\u003Cbr\u003EЦиклоспорин и такролимус\u003Cbr\u003EВлияние диклофенака на активность простагландинов в почках может усиливать нефротоксичность циклоспорина и такролимуса. В связи с этим доза диклофенака у пациентов, получающих циклоспорин или такролимус, должна быть ниже, чем у пациентов, не получающих указанные препараты.\u003Cbr\u003EПрепараты, способные вызывать гиперкалиемию\u003Cbr\u003EОдновременное применение диклофенака с калийсберегающими диуретиками, циклоспорином, такролимусом и триметопримом может привести к повышению содержания калия в плазме крови (в случае такого одновременного применения данный показатель следует часто контролировать).\u003Cbr\u003EАнтибактериальные средства - производные хинолона\u003Cbr\u003EИмеются отдельные сообщения о развитии судорог у пациентов, получавших одновременно производные хинолона и диклофенак."},{"name":"Регистрационный номер","value":"ЛСР-002352/08"},{"name":"Дата государственной регистрации","value":"05.04.2019"},{"name":"Владелец регистрационного удостоверения","value":"Татхимфармпрепараты","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["34324371:35649313","7893318:13877388"]}}},{"name":"Изготовитель","value":"Татхимфармпрепараты"},{"name":"Фасовщик","value":"Татхимфармпрепараты"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Ортофен","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["17796364:18025520"]}}},{"name":"Срок годности","value":"37 мес."}]}},"fullSpecsGrouped":{"2371723143904510049":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"опорно-двигательная система"},{"name":"Назначение","value":"аднексит, альгодисменорея, анкилозирующий спондилит, артрит, бурсит, головная боль, зубная боль, ишиас, люмбаго, миалгия, мигрень, невралгия, остеоартроз, проктит, ревматоидный артрит, тендовагинит"},{"name":"Показания к применению","value":"Воспалительные и дегенеративные заболевания опорно-двигательного аппарата в том числе: ревматоидный, ювенильный хронический артрит; анкилозирующий спондилит и другие спондилоартропатии; остеоартроз; подагрический артрит; бурсит, тендовагинит. Болевые синдромы со стороны позвоночника (люмбаго, ишиалгия, оссалгия, невралгия, миалгия, артралгия, радикулит). Посттравматический и послеоперационный болевой синдром, сопровождающийся воспалением, например, в стоматологии и ортопедии. Альгодисменорея; воспалительные процессы в малом тазу, в том числе аднексит. Изолированная лихорадка не является показанием к применению препарата. Препарат предназначен для симптоматической терапии, уменьшения боли и воспаления на момент применения, на прогрессирование заболевания не влияет."},{"name":"Противопоказания","value":"Обострение язвенной болезни желудка и двенадцатиперстной кишки, кровотечения из органов желудочно-кишечного тракта (ЖКТ), перфорация органов ЖКТ. Повышенная чувствительность к диклофенаку и любым другим компонентам препарата. III триместр беременности. Как и другие нестероидные противовоспалительные препараты (НПВП), препарат Ортофен противопоказан пациентам с полным или неполным сочетанием бронхиальной астмы, рецидивирующего полипоза носа и околоносовых пазух и непереносимости ацетилсалициловой кислоты или других НПВП (в том числе в анамнезе). Нарушение функции печени тяжелой степени тяжести, почечная недостаточность (СКФ менее 15 мл/мин/1,73 м2), хроническая сердечная недостаточность (II-IV функциональный класс по классификации NYHA). Ишемическая болезнь сердца. Цереброваскулярные заболевания, заболевания периферических артерий. Повышенный риск артериальных тромбозов и тромбоэмболий, неконтролируемая артериальная гипертензия. Состояния, сопровождающиеся риском развития кровотечений. Подтвержденная гиперкалиемия. Аортокоронарное шунтирование (периоперационный период). Воспалительные заболевания кишечника (болезнь Крона, язвенный колит) в фазе обострения. Активные заболевания печени. Период грудного вскармливания. Наследственная тяжелая непереносимость лактозы, недостаточность лактазы и глюкозо-галактозная мальабсорбция (т.к. лекарственная форма содержит лактозу). Не рекомендуется применение препарата Ортофен таблетки кишечнорастворимые, покрытые пленочной оболочкой, 25 мг у детей в возрасте до 6 лет."},{"name":"Состав","value":"1 таблетка содержит:\u003Cbr\u003EДействующее вещество: диклофенак натрия (диклофенак) - 25,0 мг.\u003Cbr\u003EВспомогательные вещества: лактозы моногидрат, сахароза, крахмал картофельный, повидон (поливинилпирролидон низкомолекулярный, пласдон К-17), кальция стеарат.\u003Cbr\u003EВспомогательные вещества оболочки: ацетилфталилцеллюлоза, титана диоксид, касторовое масло, вазелиновое масло, тропеолин 0."},{"name":"Действующее вещество","value":"Диклофенак"},{"name":"Способ применения и дозы","value":"Доза препарата подбирается индивидуально, при этом с целью снижения риска развития побочных эффектов рекомендуется применение минимальной эффективной дозы, по возможности, с максимально коротким периодом лечения в соответствии с целью лечения и состоянием пациента. Таблетки следует проглатывать целиком, запивая жидкостью, желательно до еды. Нельзя делить или разжевывать таблетки."},{"name":"Побочные действия","value":"Нарушения со стороны крови и лимфатической системы: очень редко - тромбоцитопения, лейкопения, гемолитическая анемия, апластическая анемия, агранулоцитоз.\u003Cbr\u003EНарушения со стороны иммунной системы: редко - гиперчувствительность, анафилактические/анафилактоидные реакции, включая снижение артериального давления (АД) и шок; очень редко - ангионевротический отек (включая отек лица).\u003Cbr\u003EНарушения психики: очень редко - дезориентация, депрессия, бессонница, кошмарные сновидения, раздражительность, психические нарушения.\u003Cbr\u003EНарушения со стороны нервной системы: часто - головная боль, головокружение; редко - сонливость; очень редко - нарушения чувствительности, включая парестезии, расстройства памяти, тремор, судороги, ощущение тревоги, острые нарушения мозгового кровообращения, асептический менингит.\u003Cbr\u003EНарушения со стороны органа зрения: очень редко - нарушение зрения (затуманивание зрения), диплопия.\u003Cbr\u003EНарушения со стороны органа слуха и лабиринтные нарушения: часто - вертиго; очень редко - нарушения слуха, шум в ушах.\u003Cbr\u003EНарушения со стороны сердца: нечасто - инфаркт миокарда, сердечная недостаточность, ощущение сердцебиения, боль в груди.\u003Cbr\u003EНарушения со стороны сосудов: очень редко - повышение АД, васкулит.\u003Cbr\u003EНарушения со стороны дыхательной системы, органов грудной клетки и средостения: редко - бронхиальная астма (включая одышку); очень редко - пневмонит.\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта: часто - абдоминальная боль, тошнота, рвота, диарея, диспепсия, метеоризм, снижение аппетита; редко - гастрит, желудочно-кишечное кровотечение, рвота кровью, мелена, диарея с примесью крови, язвы желудка и кишечника (с или без кровотечения, стеноза или перфорации, с возможным развитием перитонита); очень редко - стоматит, глоссит, повреждения пищевода, возникновение диафрагмоподобных стриктур в кишечнике, колит (неспецифический геморрагический колит, ишемический колит, обострение язвенного колита или болезни Крона), запор, панкреатит.\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей: часто - повышение активности аминотрансфераз в плазме крови; редко - гепатит, желтуха, нарушения функции печени; очень редко - молниеносный гепатит, некроз печени, печеночная недостаточность.\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей: часто - кожная сыпь; редко - крапивница; очень редко - буллезный дерматит, экзема, эритема, многоформная эритема, синдром Стивенса-Джонсона, синдром Лайелла (токсический эпидермальный некролиз), эксфолиативный дерматит, зуд, алопеция, реакции фоточувствительности, пурпура, пурпура Шенлейна-Геноха.\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей: очень редко - острое поражение почек (острая почечная недостаточность), гематурия, протеинурия, тубулоинтерстициальный нефрит, нефротический синдром, папиллярный некроз.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения: редко - отеки.\u003Cbr\u003EНарушения со стороны сердечно-сосудистой системы\u003Cbr\u003EДанные клинических исследований указывают на небольшое увеличение риска развития сердечно-сосудистых тромботических осложнений (например, инфаркта миокарда), особенно при длительном применении диклофенака в высоких дозах (суточная доза более 150 мг).\u003Cbr\u003EЗрительные нарушения\u003Cbr\u003EЗрительные расстройства, такие как нарушение зрения, затуманивание зрения или диплопия, по-видимому, являются класс-эффектами НПВП, и обратимы после прекращения применения. Возможным механизмом развития таких расстройств является ингибирование синтеза простагландинов и других сопутствующих веществ, что изменяет регуляцию кровотока в сетчатке, которое проявляется потенциальными зрительными расстройствами. При развитии таких симптомов на фоне терапии диклофенаком следует рассмотреть возможность офтальмологического обследования для исключения каких-либо других причин.\u003Cbr\u003EЕсли любые из указанных в инструкции побочных эффектов усугубляются, или Вы заметили любые другие побочные эффекты, не указанные в инструкции, сообщите об этом врачу."},{"name":"Фармакологическое действие","value":"Препарат содержит диклофенак натрия, вещество нестероидной структуры, оказывающее выраженное противовоспалительное, анальгезирующее и жаропонижающее действие. Основным механизмом действия диклофенака, установленным в исследованиях, считается торможение биосинтеза простагландинов. Простагландины играют важную роль в генезе воспаления, боли и лихорадки. In vitro диклофенак натрия в концентрациях, эквивалентных тем, которые достигаются при применении у человека, не подавляет биосинтез протеогликанов хрящевой ткани. При ревматических заболеваниях противовоспалительные и анальгезирующие свойства препарата обеспечивают клинический эффект, характеризующийся значительным уменьшением выраженности таких проявлений, как боль в покое и при движении, утренняя скованность и припухлость суставов, а также улучшением функционального состояния. При посттравматических и послеоперационных воспалительных явлениях диклофенак быстро купирует боль (как в покое, так и при движении), уменьшает воспалительный отек и отек послеоперационной раны. При применении препарата отмечен выраженный анальгезирующий эффект при умеренной и сильной боли неревматического происхождения. Также установлено, что диклофенак способен уменьшать болевые ощущения и снижать кровопотерю при первичной дисменорее."},{"name":"Фармакологическая группа","value":"нестероидный противовоспалительный препарат (НПВП)"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 6 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"В защищенном от света месте, при температуре не выше 25 °С. Хранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы: рвота, желудочно-кишечное кровотечение, диарея, головокружение, шум в ушах, судороги. В случае значительного отравления, возможно развитие острой почечной недостаточности и поражения печени. Лечение: поддерживающее и симптоматическое лечение показано при таких осложнениях как снижение АД, почечная недостаточность, судороги, нарушения со стороны ЖКТ и угнетение дыхания. Форсированный диурез, гемодиализ или гемоперфузия для выведения НПВП, в т.ч. диклофенака, из организма неэффективны, так как действующие вещества этих препаратов в значительной степени связываются с белками плазмы и подвергаются интенсивному метаболизму. В случае жизнеугрожающей передозировки при приеме препарата внутрь в целях скорейшего предотвращения всасывания диклофенака следует провести промывание желудка и назначить активированный уголь."},{"name":"Применение при беременности и кормлении грудью","value":"Недостаточно данных о безопасности применения диклофенака у беременных женщин, в связи с чем применять препарат Ортофен в I и II триместрах беременности следует только в тех случаях, когда ожидаемая польза для матери превышает потенциальный риск для плода. Препарат, как и другие НПВП (ингибиторы синтеза простагландинов), противопоказан в последние 3 месяца беременности (возможно подавление сократительной способности матки, нарушение функции почек у плода с последующим маловодием (олигогидроамнион) и/или преждевременное закрытие артериального протока у плода). Несмотря на то, что препарат Ортофен, как и другие НПВП, проникает в грудное молоко в малом количестве, препарат не следует применять в период грудного вскармливания во избежание нежелательного влияния на ребенка. При необходимости применения препарата у женщины в этот период грудное вскармливание прекращают. Поскольку препарат Ортофен, как и другие НПВП, может оказывать отрицательное действие на фертильность, женщинам, планирующим беременность, не рекомендуется принимать препарат. У пациенток, проходящих обследование и лечение по поводу бесплодия, препарат следует отменить."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Пациентам, у которых на фоне применения препарата Ортофен возникают зрительные нарушения, головокружение, сонливость, вертиго или другие нарушения со стороны центральной нервной системы, не следует управлять транспортными средствами и работать с механизмами."},{"name":"Особые указания","value":"Поражение ЖКТ\u003Cbr\u003EПри применении диклофенака, как и других НПВП, отмечались такие явления, как кровотечение или изъязвление/перфорация органов ЖКТ, в ряде случаев со смертельным исходом. Данные явления могут возникнуть в любое время при применении данных препаратов с или без предшествующих симптомов или серьезных заболеваний органов ЖКТ в анамнезе.\u003Cbr\u003EУ пожилых пациентов подобные осложнения могут иметь серьезные последствия. При развитии у пациентов, получающих препарат Ортофен, кровотечений или изъязвления ЖКТ препарат следует отменить.\u003Cbr\u003EДля снижения риска развития токсического действия на ЖКТ у пациентов с язвенным поражением ЖКТ, особенно осложненным кровотечением или перфорацией в анамнезе, а также у пожилых пациентов следует применять в минимальной эффективной дозе.\u003Cbr\u003EУ пациентов с повышенным риском развития желудочно-кишечных осложнений, а также у пациентов, получающих терапию низкими дозами ацетилсалициловой кислоты, на фоне терапии препаратом следует принимать гастропротекторы (ингибиторы протонной помпы или мизопростол), или другие лекарственные препараты для снижения риска нежелательного воздействия на ЖКТ.\u003Cbr\u003EПациентам с поражением ЖКТ в анамнезе, особенно пожилым, необходимо сообщать врачу обо всех абдоминальных симптомах.\u003Cbr\u003EПациенты с бронхиальной астмой\u003Cbr\u003EОбострение бронхиальной астмы (непереносимость НПВП/бронхиальная астма, провоцируемая приемом НПВП), отек Квинке и крапивница наиболее часто отмечаются у пациентов с бронхиальной астмой, сезонным аллергическим ринитом, носовыми полипами, хронической обструктивной болезнью легких или хроническими инфекционными заболеваниями дыхательных путей (особенно связанными с аллергическими риноподобными симптомами). У данной группы пациентов, а также у пациентов с аллергией на другие лекарственные препараты (кожные сыпь и зуд или крапивница) при применении препарата Ортофен следует соблюдать особую осторожность (готовность к проведению реанимационных мероприятий).\u003Cbr\u003EКожные реакции\u003Cbr\u003EТакие серьезные дерматологические реакции как эксфолиативный дерматит, синдром Стивенса-Джонсона, токсический эпидермальный некролиз, в некоторых случаях со смертельным исходом, на фоне применения диклофенака отмечались очень редко. Наибольшие риск и частота развития тяжелых дерматологических реакций отмечались в первый месяц лечения диклофенаком. При развитии у пациента, получающего препарат Ортофен, первых признаков кожной сыпи, поражений слизистых оболочек или других симптомов гиперчувствительности препарат следует отменить.\u003Cbr\u003EВ редких случаях при применении препарата Ортофен, как и других НПВП, возможно развитие анафилактических/анафилактоидных реакций у пациентов, ранее не получавших диклофенак.\u003Cbr\u003EВоздействие на печень\u003Cbr\u003EПоскольку в период применения препарата Ортофен может отмечаться повышение активности одного или нескольких \"печеночных\" ферментов, при длительной терапии препаратом в качестве меры предосторожности показан контроль функции печени. При сохранении и прогрессировании нарушений функции печени или возникновении признаков заболеваний печени или других симптомов (например, эозинофилии, сыпи и т.п.) прием препарата необходимо отменить. Следует иметь в виду, что гепатит на фоне применения препарата Ортофен может развиваться без продромальных явлений.\u003Cbr\u003EВоздействие на почки\u003Cbr\u003EНа фоне терапии препаратом рекомендуется проводить контроль функции почек у пациентов с гипертонической болезнью, нарушениями функции сердца или почек, пожилых пациентов, пациентов, принимающих диуретики или другие препараты, влияющие на функцию почек, а также у пациентов со значительным уменьшением объема внеклеточной жидкости любой этиологии, например, в период до и после массивных хирургических вмешательств. После прекращения терапии препаратом обычно отмечается нормализация показателей функции почек до исходных значений.\u003Cbr\u003EВоздействие на сердечно-сосудистую систему\u003Cbr\u003EТерапия НПВП, в том числе диклофенаком, в особенности длительная терапия и терапия с использованием высоких доз, может быть ассоциирована с небольшим возрастанием риска развития серьезных сердечно-сосудистых тромботических осложнений (включая инфаркт миокарда и инсульт).\u003Cbr\u003EУ пациентов с заболеваниями сердечно-сосудистой системы и высоким риском развития заболеваний сердечно-сосудистой системы (например, с артериальной гипертензией, гиперлипидемией, сахарным диабетом, курящих) следует применять препарат с особой осторожностью, в самой низкой эффективной дозе при минимально возможной длительности лечения, поскольку риск возникновения тромботических осложнений возрастает при увеличении дозы и продолжительности лечения.\u003Cbr\u003EПри длительной терапии (более 4 недель) суточная доза диклофенака у таких пациентов не должна превышать 100 мг. Следует периодически проводить оценку эффективности лечения и потребности пациента в симптоматической терапии, особенно в тех случаях, когда ее продолжительность составляет более 4 недель. При появлении первых симптомов тромботических нарушений (например, боли в груди, чувства нехватки воздуха, слабости, нарушения речи) пациенту следует незамедлительно обратиться за медицинской помощью.\u003Cbr\u003EВоздействие на систему кроветворения\u003Cbr\u003EПрепарат может временно ингибировать агрегацию тромбоцитов, поэтому у пациентов с нарушениями гемостаза необходимо проводить тщательный контроль соответствующих лабораторных показателей.\u003Cbr\u003EПри длительном применении препарата Ортофен рекомендуется проводить регулярные клинические анализы периферической крови.\u003Cbr\u003EМаскирование признаков инфекционного процесса\u003Cbr\u003EПротивовоспалительное действие препарата Ортофен может затруднять диагностику инфекционных процессов.\u003Cbr\u003EПрименение одновременно с другими НПВП\u003Cbr\u003EНе следует применять препарат одновременно с другими НПВП, включая селективные ингибиторы ЦОГ-2 из-за риска нежелательных явлений."},{"name":"Взаимодействие","value":"Выявленные взаимодействия\u003Cbr\u003EИнгибиторы изофермента CYP2C9\u003Cbr\u003EСледует соблюдать осторожность при одновременном применении диклофенака и ингибиторов изофермента CYP2C9 (таких как вориконазол) из-за возможного увеличения концентрации диклофенака в сыворотке крови и его экспозиции.\u003Cbr\u003EЛитий, дигоксин\u003Cbr\u003EДиклофенак может повышать концентрации лития и дигоксина в плазме крови. Рекомендуется контролировать содержания лития и концентрации дигоксина в сыворотке крови.\u003Cbr\u003EДиуретические и гипотензивные средства\u003Cbr\u003EПри одновременном применении с диуретиками и гипотензивными препаратами (например, бета-адреноблокаторами, ингибиторами ангиотензин-превращающего фермента - АПФ) диклофенак может снижать их гипотензивное действие. В связи с вышесказанным у пациентов, особенно пожилого возраста, при одновременном применении диклофенака и диуретиков или гипотензивных средств следует регулярно измерять АД, контролировать функцию почек и степень гидратации (вследствие повышения риска нефротоксичности).\u003Cbr\u003EЦиклоспорин и такролимус\u003Cbr\u003EВлияние диклофенака на активность простагландинов в почках может усиливать нефротоксичность циклоспорина и такролимуса. В связи с этим доза диклофенака у пациентов, получающих циклоспорин или такролимус, должна быть ниже, чем у пациентов, не получающих указанные препараты.\u003Cbr\u003EПрепараты, способные вызывать гиперкалиемию\u003Cbr\u003EОдновременное применение диклофенака с калийсберегающими диуретиками, циклоспорином, такролимусом и триметопримом может привести к повышению содержания калия в плазме крови (в случае такого одновременного применения данный показатель следует часто контролировать).\u003Cbr\u003EАнтибактериальные средства - производные хинолона\u003Cbr\u003EИмеются отдельные сообщения о развитии судорог у пациентов, получавших одновременно производные хинолона и диклофенак."},{"name":"Регистрационный номер","value":"ЛСР-002352/08"},{"name":"Дата государственной регистрации","value":"05.04.2019"},{"name":"Владелец регистрационного удостоверения","value":"Татхимфармпрепараты"},{"name":"Изготовитель","value":"Татхимфармпрепараты"},{"name":"Фасовщик","value":"Татхимфармпрепараты"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Ортофен"},{"name":"Срок годности","value":"37 мес."}]}],"transitionId":"tr_4440465473889061033"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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27 ₽

  • Завтра, самовывоз • 0 ₽
ЕАПТЕКА
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  • Коллаген для суставов капс., 120 шт.
    –21 %
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    Коллаген для суставов капс., 120 шт.

    Рейтинг товара: 4.7 из 5
    на основе 681 оценка
    С картой  Пэй
    Цена с картой Яндекс Пэй 754 ₽ вместо 770
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  • Глюкозамин-хондроитиновый комплекс капс., 90 шт.
    –1 %
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    Глюкозамин-хондроитиновый комплекс капс., 90 шт.

    Рейтинг товара: 4.8 из 5
    на основе 48 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 396 ₽ вместо 400
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  • Хонда капс., 30 шт., 1 уп.
    –1 %
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    Хонда капс., 30 шт., 1 уп.

    Рейтинг товара: 5 из 5
    на основе 7 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 503 ₽ вместо 508
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  • Лошадиная сила бальзам-гель Релаксирующий, 125 мл, 125 г, 1 шт., ментол, 1 уп.
    ВАМ–49 %
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    Лошадиная сила бальзам-гель Релаксирующий, 125 мл, 125 г, 1 шт., ментол, 1 уп.

    Рейтинг товара: 4.8 из 5
    на основе 263 оценки
    Цена 395 ₽ вместо 780
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  • Артро-Актив Первая помощь капс., 36 шт.
    –1 %
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    Артро-Актив Первая помощь капс., 36 шт.

    Рейтинг товара: 4.6 из 5
    на основе 22 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 247 ₽ вместо 249
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  • Глюкозамин-хондроитиновый комплекс Ультра капс., 90 шт.
    –1 %
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    Глюкозамин-хондроитиновый комплекс Ультра капс., 90 шт.

    Рейтинг товара: 4.8 из 5
    на основе 57 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 470 ₽ вместо 475
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  • Артроцин форте капс., 36 шт., 1 уп.
    –1 %
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    Артроцин форте капс., 36 шт., 1 уп.

    Рейтинг товара: 5 из 5
    на основе 2 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 396 ₽ вместо 400
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  • Диклозан Форте с глюкозамином крем д/нар. прим., 75 мл, 1 шт.
    –1 %
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    Диклозан Форте с глюкозамином крем д/нар. прим., 75 мл, 1 шт.

    Рейтинг товара: 5 из 5
    на основе 4 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 195 ₽ вместо 197
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  • Суставит Крымская маклюра гель-бальзам д/тела, 125 мл, 145 г, 1 шт., 1 уп.
    –1 %
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    Суставит Крымская маклюра гель-бальзам д/тела, 125 мл, 145 г, 1 шт., 1 уп.

    Рейтинг товара: 4.7 из 5
    на основе 90 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 249 ₽ вместо 252
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  • Геладринк форте пор. д/приг. р-ра д/вн. приема, 420 г, апельсин
    –1 %
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    Геладринк форте пор. д/приг. р-ра д/вн. приема, 420 г, апельсин

    Рейтинг товара: 4.8 из 5
    на основе 436 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 3 753 ₽ вместо 3 791
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  • Артнео капс., 35 г, 30 шт., нейтральный, 1 уп.
    –68 %
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    Артнео капс., 35 г, 30 шт., нейтральный, 1 уп.

    Рейтинг товара: 4.8 из 5
    на основе 293 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 1 362 ₽ вместо 1 390
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Инструкция

Показания к применению

Воспалительные и дегенеративные заболевания опорно-двигательного аппарата в том числе: ревматоидный, ювенильный хронический артрит; анкилозирующий спондилит и другие спондилоартропатии; остеоартроз; подагрический артрит; бурсит, тендовагинит. Болевые синдромы со стороны позвоночника (люмбаго, ишиалгия, оссалгия, невралгия, миалгия, артралгия, радикулит). Посттравматический и послеоперационный болевой синдром, сопровождающийся воспалением, например, в стоматологии и ортопедии. Альгодисменорея; воспалительные процессы в малом тазу, в том числе аднексит. Изолированная лихорадка не является показанием к применению препарата. Препарат предназначен для симптоматической терапии, уменьшения боли и воспаления на момент применения, на прогрессирование заболевания не влияет.

Противопоказания

Обострение язвенной болезни желудка и двенадцатиперстной кишки, кровотечения из органов желудочно-кишечного тракта (ЖКТ), перфорация органов ЖКТ. Повышенная чувствительность к диклофенаку и любым другим компонентам препарата. III триместр беременности. Как и другие нестероидные противовоспалительные препараты (НПВП), препарат Ортофен противопоказан пациентам с полным или неполным сочетанием бронхиальной астмы, рецидивирующего полипоза носа и околоносовых пазух и непереносимости ацетилсалициловой кислоты или других НПВП (в том числе в анамнезе). Нарушение функции печени тяжелой степени тяжести, почечная недостаточность (СКФ менее 15 мл/мин/1,73 м2), хроническая сердечная недостаточность (II-IV функциональный класс по классификации NYHA). Ишемическая болезнь сердца. Цереброваскулярные заболевания, заболевания периферических артерий. Повышенный риск артериальных тромбозов и тромбоэмболий, неконтролируемая артериальная гипертензия. Состояния, сопровождающиеся риском развития кровотечений. Подтвержденная гиперкалиемия. Аортокоронарное шунтирование (периоперационный период). Воспалительные заболевания кишечника (болезнь Крона, язвенный колит) в фазе обострения. Активные заболевания печени. Период грудного вскармливания. Наследственная тяжелая непереносимость лактозы, недостаточность лактазы и глюкозо-галактозная мальабсорбция (т.к. лекарственная форма содержит лактозу). Не рекомендуется применение препарата Ортофен таблетки кишечнорастворимые, покрытые пленочной оболочкой, 25 мг у детей в возрасте до 6 лет.

Способ применения и дозы

Доза препарата подбирается индивидуально, при этом с целью снижения риска развития побочных эффектов рекомендуется применение минимальной эффективной дозы, по возможности, с максимально коротким периодом лечения в соответствии с целью лечения и состоянием пациента. Таблетки следует проглатывать целиком, запивая жидкостью, желательно до еды. Нельзя делить или разжевывать таблетки.
Полная инструкция
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Ортофен таб. п/о плен. кш/раств.
Ортофен таб. п/о плен. кш/раств., 25 мг, 20 шт.
5.0
(11)
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Инструкция

27 ₽

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5.0
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    Цена 28 ₽
  • Глюкозамин-хондроитиновый комплекс капс., 90 шт.
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    Глюкозамин-хондроитиновый комплекс капс., 90 шт.

    Цена 396 ₽ вместо 400
  • Хонда капс., 30 шт., 1 уп.
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    Хонда капс., 30 шт., 1 уп.

    Цена 503 ₽ вместо 508
  • Коллаген для суставов капс., 120 шт.
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    Коллаген для суставов капс., 120 шт.

    Цена 754 ₽ вместо 950
  • Vitamin D3, 50000 МЕ, 50 мл, 50 шт.
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    Vitamin D3, 50000 МЕ, 50 мл, 50 шт.

    Цена 1 355 ₽ вместо 1 940
  • Артро-Актив Первая помощь капс., 36 шт.
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    Артро-Актив Первая помощь капс., 36 шт.

    Цена 247 ₽ вместо 249
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    Реклама
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  • Анальгин таб., 500 мг, 10 шт.
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    Анальгин таб., 500 мг, 10 шт.

    Цена 18 ₽
  • Глюкозамин-хондроитиновый комплекс Ультра капс., 90 шт.
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    Глюкозамин-хондроитиновый комплекс Ультра капс., 90 шт.

    Цена 470 ₽ вместо 475
  • Лошадиная сила бальзам-гель Релаксирующий, 125 мл, 125 г, 1 шт., ментол, 1 уп.
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    Лошадиная сила бальзам-гель Релаксирующий, 125 мл, 125 г, 1 шт., ментол, 1 уп.

    Цена 395 ₽ вместо 780
  • Артроцин форте капс., 36 шт., 1 уп.
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    Артроцин форте капс., 36 шт., 1 уп.

    Цена 396 ₽ вместо 400
  • Диклозан Форте с глюкозамином крем д/нар. прим., 75 мл, 1 шт.
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    Диклозан Форте с глюкозамином крем д/нар. прим., 75 мл, 1 шт.

    Цена 195 ₽ вместо 197
  • Суставит Крымская маклюра гель-бальзам д/тела, 125 мл, 145 г, 1 шт., 1 уп.
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    Суставит Крымская маклюра гель-бальзам д/тела, 125 мл, 145 г, 1 шт., 1 уп.

    Цена 249 ₽ вместо 252
  • Геладринк форте пор. д/приг. р-ра д/вн. приема, 420 г, апельсин
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    Геладринк форте пор. д/приг. р-ра д/вн. приема, 420 г, апельсин

    Цена 3 753 ₽ вместо 3 791
  • Артнео капс., 35 г, 30 шт., нейтральный, 1 уп.
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    Артнео капс., 35 г, 30 шт., нейтральный, 1 уп.

    Цена 1 362 ₽ вместо 4 225
  • Нафтизин капли наз. фл.-кап., 0.1%, 10 мл
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    Нафтизин капли наз. фл.-кап., 0.1%, 10 мл

    Цена 18 ₽
  • Парацетамол таб., 500 мг, 10 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:228062752_18/content/content/toggleWishlist":{"skuId":"101344102777","productId":228062752,"offerId":"Kwy-uOISsuxUglmnSgf2ig","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQk7PXvKqqlfgwEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCKDs32wQ+ZLRxPkCGI+83gcg7dnBBw==","sign":"RnnLGNYd+2x/xikaYwgk6SC1iUN8PBEJtlKmhYkx2og="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:228062752_18/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Парацетамол таб., 500 мг, 10 шт.

    Цена 11 ₽
  • Гилан ультра комфорт увлажн. гл. р-р, 0.3%, 0.4 мл, 50 г, 10 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1417729433_19/content/content/gallery":{"title":"Гилан ультра комфорт увлажн. гл. р-р, 0.3%, 0.4 мл, 50 г, 10 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/4493501/img_id518890055591967969.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4493501/img_id518890055591967969.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4493501/img_id518890055591967969.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4493501/img_id518890055591967969.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4493501/img_id518890055591967969.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4493501/img_id518890055591967969.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/1538707/img_id7406584760491012505.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/1538707/img_id7406584760491012505.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/1538707/img_id7406584760491012505.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/1538707/img_id7406584760491012505.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/1538707/img_id7406584760491012505.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/1538707/img_id7406584760491012505.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQk7PXvKqqlfgwEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCJmrg6QFEKucmNsBGIfe0Acg3NzBBw==","sign":"3v5qKLWgFKix90t5QfjvSTrC9KqVdEoEzto2nUNSAzQ="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1417729433_19/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1417729433_19/content/content/toggleWishlist":{"skuId":"459673131","productId":1417729433,"offerId":"UBfQcstXjheSpOoAYOfXvw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQk7PXvKqqlfgwEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCJmrg6QFEKucmNsBGIfe0Acg3NzBBw==","sign":"3v5qKLWgFKix90t5QfjvSTrC9KqVdEoEzto2nUNSAzQ="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1417729433_19/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Гилан ультра комфорт увлажн. гл. р-р, 0.3%, 0.4 мл, 50 г, 10 шт.

    Цена 288 ₽ вместо 331
  • Цитрамон П таб., 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:186609932_20/content/content/toggleWishlist":{"skuId":"102013807781","productId":186609932,"offerId":"rDA9BfbROEJKrOwcKd6zQg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQk7PXvKqqlfgwEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCIzi/VgQpdn8g/wCGI+83gcg7dnBBw==","sign":"X5Q7dGAbMGjV8pCsR9zD3wu+6p3AB8V/iWAyuDr6D44="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:186609932_20/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Цитрамон П таб., 30 шт.

    Цена 95 ₽ вместо 96
  • {"widgets":{"@light/BannerCurtain":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_102_21/content/content/content/bannerCurtain":{"advertisementId":2071421,"impression":"/safeclick/data=SpQw45JhDGE6zDtOdUQO_HcJB4i-wRmE0HcHl_5Egdhw8Pm8UJd_q-myMBRTxLEgSZhZKEszFieT9FQtVeNhjF-I35hAfK71akUDkkZuU-sF0LNAkmZibeZHcAk7JDqMNkCCnprh5SdusACWU9R0hp4SB6WGosVIbVL3-0GKoS4-F6tDfVoEjzLN7739Bewnw44dKyKbS5Otqo3EjWDPkAXXe5UNeQPEcikxbkd1gtcNfE--5QX3SiCJcDhK4et__8IPCOTsGUABYh4Y2MsvrsSB9L564jnh5xyexDdGQu0aLNX61JbAcPyOBSMmpW4kk1fT8nmo-YKcrinzBURdzWA9rrNxaOuIqY_qGfQbo4qjE_3sNoiBgtrer2-71scHj956lFmQzoVzT31G9Z-WdrNTlvK_AyZqAxoqPUvT7FaLRtZuo1pKYWOW7qhfHAz3m3GfGF6Zg15zu8AybezdniDWwrzcesYV4mLXJGst8rcuR2u2yX0Km8DGwcEiA7wmrMJ-8vRLtDUjGg_qf0Df-LlsA-TVOYFY3lX1APQAAe52LAICalUa0D6pIOEb0fieFHGHDHCwA3CyTZwQWxtW5RtQICAZr6GK2mif5j7opD6ye6rY856Dspsjfbdk16sH-uAdtxXusKZ_XQk6Dkv2bBJ5dXgepqhrHapntE8NUHz02RLwyQpC3cNuugI9e6TD4C-PaK0OW2FzVptY2Vvmlhh80hesOo_rMfXMz4XteBeBPDyE2EgIjlANJllXkdTdI3lfShr_CPvF5Rejb7QGYbBB-rZFbfTXIaRrGhRrBiOuOL3ZlnqRmggAOUCvfBboc7VyEHDmOBODEcz79-a4BJy3k-CXf1Xk-IiXnO5-wn2v0QiXOKrBR16bnBFt8Z-TCwcmri_Q7mRSf2vcj3bK653HVGBJgqFYCBcCGm_fh1OKP6HOLc0UY0TrxdCb6VfqODbYiOFR9fNaq4oofnwdpy3BTLVvA83Lb_NObEiaV1ePv4Ldj_odndBlwPZA-Gf8uUfQAmVlQFG_TLv91-kx4nQaFsj_NGIPRGvc7Kyv1yYuQ9OP2skcQPNYRpbWuNG1G8aiC3mmd_rRmyX8xY6Hf2n2bwk3tBBB/b64e=1/sign=21ad1ad841ccd5c2dc30a59f762900d4/keyno=MARKET_1/*"}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_102_21/content/content/content/bannerCurtain":{"name":"@light/BannerCurtain"}}}
    {"widgets":{"@monetize/Kebab":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_102_21/content/content/content/kebab":{"adLabel":{"adLabelText":"Реклама","advertizer":"АКЦИОНЕРНОЕ ОБЩЕСТВО \"АЛЬФА-БАНК\", ИНН 7728168971, ID #e-1g-105699-VND-ADV","adLabel":1},"advertisementId":2071421}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_102_21/content/content/content/kebab":{"name":"@monetize/Kebab"}}}
    Реклама
    {"widgets":{"@light/AdLabel":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_102_21/content/content/content/adLabel":{"adLabel":{"adLabelText":"Реклама","advertizer":"АКЦИОНЕРНОЕ ОБЩЕСТВО \"АЛЬФА-БАНК\", ИНН 7728168971, ID #e-1g-105699-VND-ADV","adLabel":1},"advertisementId":2071421,"allowDebug":false,"borderRadius":5,"indents":6}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_102_21/content/content/content/adLabel":{"name":"@light/AdLabel"}}}
    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  • Эвалар Чай Эвалар БИО при повышенном содержании мочевой кислоты, 20 фильтр-пакетов
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    Эвалар Чай Эвалар БИО при повышенном содержании мочевой кислоты, 20 фильтр-пакетов

    Цена 194 ₽ вместо 224
  • БиоГая Пробиотик капли детск. фл., 5 мл, 1 уп.
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    БиоГая Пробиотик капли детск. фл., 5 мл, 1 уп.

    Цена 1 752 ₽ вместо 3 500
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