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Описание

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Тамсулозин Канон таб. пролонг. высвоб. п/о плен. плён., 0.4 мг, 30 шт.

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Коротко о товаре

Артикул Маркета
3639120108
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
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Длительность применения не ограничена, препарат назначают в виде непрерывной терапии.\u003Cbr\u003EТаблетка должна быть принята целиком, ее нельзя разжевывать, так как это может повлиять на скорость высвобождения препарата.\u003Cbr\u003EСиндром отмены отсутствует."},{"name":"Побочные действия","value":"Частота нежелательных реакций, развивающихся при приеме тамсулозина, классифицирована согласно рекомендациям Всемирной организации здравоохранения (ВОЗ): очень часто (≥1/10 случаев); часто (≥1/100, \u003C1/10 случаев); нечасто (≥1/1000, \u003C1/100 случаев); редко (≥1/10000, \u003C1 1000 случаев); очень редко (\u003C1 10000 случаев): частота неизвестна - по имеющимся данным установить частоту возникновения не представлялось возможным.\u003Cbr\u003EНарушения со стороны нервной системы:\u003Cbr\u003Eчасто - головокружение;\u003Cbr\u003Eнечасто - головная боль;\u003Cbr\u003Eредко - обморок.\u003Cbr\u003EНарушения со стороны органа зрения:\u003Cbr\u003Eчастота неизвестна - интраоперационная нестабильность радужной оболочки глаза (синдром узкого зрачка) при операции по поводу катаракты, глаукомы.\u003Cbr\u003EНарушения со стороны сердца:\u003Cbr\u003Eнечасто - \"ощущение сердцебиения\";\u003Cbr\u003EНарушения со стороны сосудов:\u003Cbr\u003Eнечасто - ортостатическая гипотензия.\u003Cbr\u003EНарушения со стороны дыхательной системы, органов грудной клетки и средостения:\u003Cbr\u003Eнечасто - ринит;\u003Cbr\u003Eчастота неизвестна - носовое кровотечение.\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта:\u003Cbr\u003Eнечасто - запор, диарея, тошнота, рвота;\u003Cbr\u003Eчастота неизвестна - сухость во рту.\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей:\u003Cbr\u003Eнечасто - сыпь, зуд. крапивница;\u003Cbr\u003Eредко - ангионевротический отек;\u003Cbr\u003Eочень редко - синдром Стивенса - Джонсона;\u003Cbr\u003Eчастота неизвестна - многоформная эритема, эксфолиативный дерматит.\u003Cbr\u003EНарушения со стороны половых органов и молочной железы:\u003Cbr\u003Eчасто - нарушение эякуляции (включая ретроградную эякуляцию, эякуляционную недостаточность);\u003Cbr\u003Eочень редко -приапизм.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения:\u003Cbr\u003Eнечасто - астения.\u003Cbr\u003EВ дополнение к нежелательным реакциям, описанным выше, при использовании тамсулозина наблюдались фибрилляция предсердий, аритмия, тахикардия и одышка. В связи с тем, что данные были получены методом спонтанных сообщений в период после регистрации, определение частоты и причинно-следственной связи этих явлений с приемом тамсулозина представляется затруднительным.\u003Cbr\u003EЕсли любые из указанных в инструкции нежелательных реакций усугубляются, или Вы заметили любые другие нежелательные реакции, нс указанные в инструкции, сообщите об этом врачу."},{"name":"Фармакологическое действие","value":"Тамсулозин является специфическим конкурентным блокатором постсинаптических α-адренорецепторов, особенно α1А и α1D подтипов, отвечающих за расслабление гладкой мускулатуры предстательной железы, шейки мочевого пузыря и простатической части уретры. Тамсулозин в дозировке 0,4 мг увеличивает максимальную скорость мочеиспускания, а также снижает тонус гладкой мускулатуры предстательной железы и уретры, улучшая отток мочи и. таким образом, уменьшение симптомов опорожнения и наполнения мочевого пузыря. Тамсулозин также уменьшает выраженность симптомов наполнения, в развитии которых важную роль играет гиперактивность детрузора.\u003Cbr\u003EПри длительной терапии сохраняется воздействие на выраженность симптомов наполнения и опорожнения, уменьшая риск развития острой задержки мочи и необходимость оперативного вмешательства.\u003Cbr\u003EКак правило, терапевтический эффект развивается через 2 недели после начала приема препарата, хотя у ряда пациентов уменьшение выраженности симптомов отмечается после приема первой дозы. Способность тамсулозина воздействовать на α1А подтип адренорецепторов в 20 раз превосходит его способность взаимодействовать с α1В подтипом адренорецепторов, которые расположены в гладких мышцах сосудов. Благодаря такой высокой селективности препарат не вызывает какого-либо клинически значимого снижения системного артериального давления (ЛД) как у пациентов с артериальной гипертензией, так и у пациентов с нормальными показателями артериального давления.\u003Cbr\u003EПри применении тамсулозина в суточной дозе 0,4 мг случаев клинически значимого снижения артериального давления не отмечалось."},{"name":"Фармакологическая группа","value":"альфа1-адреноблокатор"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["35947170:36763744"]}}},{"name":"Пол","value":"для мужчин","transition":{"type":"catalog","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["14805991:14805992"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"При температуре не выше 25 °C во вторичной упаковке (пачке картонной).\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"Нет сообщений о случаях острой передозировки тамсулозином.\u003Cbr\u003EСимптомы: снижение артериального давления, компенсаторная тахикардия. Лечение симптоматическое. Артериальное давление и частота сердечных сокращений могут восстановиться при принятии больным горизонтального положения. При отсутствии эффекта можно применить средства, увеличивающие объем циркулирующей крови и, если необходимо, сосудосуживающие средства. Необходимо контролировать функцию почек. Маловероятно, что диализ будет эффективен, так как тамсулозин интенсивно связывается с белками плазмы.\u003Cbr\u003EДля предотвращения дальнейшего всасывания препарата целесообразно промывание желудка, прием активированного угля и осмотических слабительных."},{"name":"Применение при беременности и кормлении грудью","value":"Препарат Тамсулозин Канон предназначен для применения только у лиц мужского пола."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Влияние применения тамсулозина на способность к управлению транспортными средствами и механизмами не изучалось. Тем не менее, в связи с возможным головокружением, следует воздержаться от управления транспортными средствами и механизмами, а также занятием деятельностью, требующей повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"Как и при использовании других α1-адреноблокаторов. при лечении тамсулозином в отдельных случаях может наблюдаться снижение АД, которое иногда может приводить к обморочному состоянию. При первых признаках ортостатической гипотензии (головокружение, слабость) пациент должен сесть или лечь и оставаться в этом положении до тех пор, пока признаки не исчезнут.\u003Cbr\u003EПрежде чем начать терапию тамсулозином, пациент должен быть обследован с тем, чтобы исключить наличие других заболеваний, которые могут вызывать такие же симптомы, как и доброкачественная гиперплазия простаты. Перед началом лечения и регулярно во время терапии должно выполняться пальцевое ректальное обследование и, если требуется, определение простатического специфического антигена (ПСА).\u003Cbr\u003EУ некоторых пациентов при оперативных вмешательствах но поводу катаракты или глаукомы на фоне приема препарата возможно развитие синдрома интраоперационной нестабильности радужной оболочки глаза (синдром узкого зрачка), который может привести к осложнениям во время операции иди в послеоперационном периоде. Целесообразность отмены терапии тамсулозином за 1-2 недели до операции но поводу катаракты или глаукомы не доказана. Случаи интраоперациопиой нестабильности радужной оболочки глаза имели место у пациентов, прекративших прием препарата и в более ранние сроки перед операцией. Не рекомендуется начинать терапию тамсулозином у пациентов, которым запланирована операция но поводу катаракты или глаукомы. Во время предоперационного обследования пациентов хирург и врач-офтальмолог должны учитывать, принимает или принимал ли данный пациент тамсулозин. Эго необходимо для подготовки к возможности развития во время операции интраоперационной нестабильности радужной оболочки глаза.\u003Cbr\u003EВ случае развития ангионевротического отека следует немедленно прекратить терапию препаратом. Повторное назначение тамсулозина противопоказано.\u003Cbr\u003EЛечение тамсулозином пациентов с почечной недостаточностью тяжелой степени (клиренс креатинина менее 10 мл/мин) требует осторожности, т.к. исследований у этой категории пациентов не проводилось.\u003Cbr\u003EПри почечной недостаточности легкой и средней степени тяжести, а также при печеночной недостаточности легкой или средней степени тяжести не требуется коррекция режима дозирования.\u003Cbr\u003EИмеются сообщения о случаях развития длительной эрекции и приапизма на фоне терапии альфа-1-адреноблокаторами. В случае сохранения эрекции до 4- х часов следует немедленно обратиться за медицинской помощью. Если терапия приапизма не была проведена незамедлительно, это может привести к повреждению тканей полового члена и необратимой утрате потенции.\u003Cbr\u003EС осторожностью:\u003Cbr\u003EПочечная недостаточность тяжелой степени (клиренс креатинина менее 10 мл/мин), артериальная гипотензия, при одновременном применении с мощными и средней активности ингибиторами изофермента CYP3A4."},{"name":"Взаимодействие","value":"При совместном применении тамсулозина с атенололом, эналаприлом, нифедипином или теофиллином взаимодействии обнаружено не было.\u003Cbr\u003EПри одновременном применении с циметидином отмечено некоторое повышение концентрации тамсулозина в плазме крови, с фуросемидом - снижение концентрации, однако, это не требует изменения дозы тамсулозина, поскольку концентрация препарата остается в пределах нормального диапазона. Диазепам, пропранолол, трихлорметиазид. хлормадинон, амитриптилин, диклофенак, глибенкламид, симвастатин и варфарин нс изменяют свободную фракцию тамсулозина в плазме человека in vitro. В свою очередь, тамсулозин также не изменяет свободные фракции диазепама, пропранолола, трихлорметиазида и хлормадинона.\u003Cbr\u003EВ исследованиях in vitro не было обнаружено взаимодействия на уровне печеночного метаболизма с амитриптиллином, сальбутамолом, глибенкламидом и финастеридом. Диклофенак и варфарин могут увеличивать с скорость выведения тамсулозина.\u003Cbr\u003EОдновременное применение тамсулозина с мощными ингибиторами изофермента CYP3A4 может привести к увеличению концентрации тамсулозина. Одновременное применение с кетоконазолом (мощный ингибитор изофермента CYP3A4) приводило к увеличению площади под фармакокинетической кривой \"концентрация-время\" (AUC) и максимальной концентрации (Сmах) тамсулозина в 2.8 и 2,2 раза соответственно. Тамсулозин не следует назначать в комбинации с мощными ингибиторами изофермента CYP3A4 у пациентов с нарушением метаболизма изофермента CYP2D6. Препарат следует использовать с осторожностью в комбинации с мощными и средней активности ингибиторами изофермента CYP3A4.\u003Cbr\u003EОдновременное назначение тамсулозина и пароксетина, мощного ингибитора изофермента CYP2D6, приводило к увеличению Сmах и AUC тамсулозина в 1,3 и 1,6 раза, соответственно, однако данное увеличение признано клинически незначимым.\u003Cbr\u003EОдновременное назначение других блокаторов α1-адренорецепторов может привести к гипотензивному эффекту."},{"name":"Регистрационный номер","value":"ЛП-004253"},{"name":"Дата государственной регистрации","value":"10.04.2020"},{"name":"Владелец регистрационного удостоверения","value":"Канонфарма продакшн","transition":{"type":"catalog","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["34324371:35649313","7893318:16146766"]}}},{"name":"Изготовитель","value":"Канонфарма продакшн"},{"name":"Фасовщик","value":"Канонфарма продакшн"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Тамсулозин Канон","transition":{"type":"catalog","params":{"categorySlug":"mochepolovaia-sistema-i-polovye-gormony","categoryId":"15756910","navnodeId":"72506","glfilters":["17796364:18039805"]}}},{"name":"Срок годности","value":"24 мес."}]}},"fullSpecsGrouped":{"7855437522899942365":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"половая система, половые железы"},{"name":"Назначение","value":"дизурия, доброкачественная гиперплазия предстательной железы"},{"name":"Показания к применению","value":"Лечение дизурических расстройств при доброкачественной гиперплазии предстательной железы."},{"name":"Противопоказания","value":"- Гиперчувствительность к тамсулозину (включая ангионевротический отек) и/или к любому вспомогательному веществу в составе препарата;\u003Cbr\u003E- ортостатическая гипотензия (в т. ч. в анамнезе);\u003Cbr\u003E- печеночная недостаточность тяжелой степени;\u003Cbr\u003E- возраст до 18 лет;\u003Cbr\u003E- дефицит лактазы, непереносимость лактозы, синдром глюкозогалактозной мальабсорбции."},{"name":"Состав","value":"1 таблетка с пролонгированным высвобождением, покрытая пленочной оболочкой 0,4 мг, содержит:\u003Cbr\u003Eдействующее вещество: тамсулозина гидрохлорид 0,40 мг;\u003Cbr\u003Eвспомогательные вещества: гипромеллоза (гидроксипропилметилцеллюлоза) 71,60 мг, кремния диоксид коллоидный 1,20 мг, лактозы моногидрат 15,40 мг, магния стеарат 2,40 мг, целлюлоза микрокристаллическая 149,00 мг;\u003Cbr\u003Eпленочная оболочка: Опадрай II желтый 85F32410 7,00 мг, в том числе: поливиниловый спирт 2,800 мг , макрогол (полиэтиленгликоль) 1,414 мг, тальк 1,036 мг, титана диоксид 1,645 мг, краситель железа оксид желтый 0,105 мг."},{"name":"Действующее вещество","value":"Taмcyлoзин"},{"name":"Способ применения и дозы","value":"Внутрь, по 1 таблетке (0,4 мг) 1 раз в сутки независимо от приема пищи. Длительность применения не ограничена, препарат назначают в виде непрерывной терапии.\u003Cbr\u003EТаблетка должна быть принята целиком, ее нельзя разжевывать, так как это может повлиять на скорость высвобождения препарата.\u003Cbr\u003EСиндром отмены отсутствует."},{"name":"Побочные действия","value":"Частота нежелательных реакций, развивающихся при приеме тамсулозина, классифицирована согласно рекомендациям Всемирной организации здравоохранения (ВОЗ): очень часто (≥1/10 случаев); часто (≥1/100, \u003C1/10 случаев); нечасто (≥1/1000, \u003C1/100 случаев); редко (≥1/10000, \u003C1 1000 случаев); очень редко (\u003C1 10000 случаев): частота неизвестна - по имеющимся данным установить частоту возникновения не представлялось возможным.\u003Cbr\u003EНарушения со стороны нервной системы:\u003Cbr\u003Eчасто - головокружение;\u003Cbr\u003Eнечасто - головная боль;\u003Cbr\u003Eредко - обморок.\u003Cbr\u003EНарушения со стороны органа зрения:\u003Cbr\u003Eчастота неизвестна - интраоперационная нестабильность радужной оболочки глаза (синдром узкого зрачка) при операции по поводу катаракты, глаукомы.\u003Cbr\u003EНарушения со стороны сердца:\u003Cbr\u003Eнечасто - \"ощущение сердцебиения\";\u003Cbr\u003EНарушения со стороны сосудов:\u003Cbr\u003Eнечасто - ортостатическая гипотензия.\u003Cbr\u003EНарушения со стороны дыхательной системы, органов грудной клетки и средостения:\u003Cbr\u003Eнечасто - ринит;\u003Cbr\u003Eчастота неизвестна - носовое кровотечение.\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта:\u003Cbr\u003Eнечасто - запор, диарея, тошнота, рвота;\u003Cbr\u003Eчастота неизвестна - сухость во рту.\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей:\u003Cbr\u003Eнечасто - сыпь, зуд. крапивница;\u003Cbr\u003Eредко - ангионевротический отек;\u003Cbr\u003Eочень редко - синдром Стивенса - Джонсона;\u003Cbr\u003Eчастота неизвестна - многоформная эритема, эксфолиативный дерматит.\u003Cbr\u003EНарушения со стороны половых органов и молочной железы:\u003Cbr\u003Eчасто - нарушение эякуляции (включая ретроградную эякуляцию, эякуляционную недостаточность);\u003Cbr\u003Eочень редко -приапизм.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения:\u003Cbr\u003Eнечасто - астения.\u003Cbr\u003EВ дополнение к нежелательным реакциям, описанным выше, при использовании тамсулозина наблюдались фибрилляция предсердий, аритмия, тахикардия и одышка. В связи с тем, что данные были получены методом спонтанных сообщений в период после регистрации, определение частоты и причинно-следственной связи этих явлений с приемом тамсулозина представляется затруднительным.\u003Cbr\u003EЕсли любые из указанных в инструкции нежелательных реакций усугубляются, или Вы заметили любые другие нежелательные реакции, нс указанные в инструкции, сообщите об этом врачу."},{"name":"Фармакологическое действие","value":"Тамсулозин является специфическим конкурентным блокатором постсинаптических α-адренорецепторов, особенно α1А и α1D подтипов, отвечающих за расслабление гладкой мускулатуры предстательной железы, шейки мочевого пузыря и простатической части уретры. Тамсулозин в дозировке 0,4 мг увеличивает максимальную скорость мочеиспускания, а также снижает тонус гладкой мускулатуры предстательной железы и уретры, улучшая отток мочи и. таким образом, уменьшение симптомов опорожнения и наполнения мочевого пузыря. Тамсулозин также уменьшает выраженность симптомов наполнения, в развитии которых важную роль играет гиперактивность детрузора.\u003Cbr\u003EПри длительной терапии сохраняется воздействие на выраженность симптомов наполнения и опорожнения, уменьшая риск развития острой задержки мочи и необходимость оперативного вмешательства.\u003Cbr\u003EКак правило, терапевтический эффект развивается через 2 недели после начала приема препарата, хотя у ряда пациентов уменьшение выраженности симптомов отмечается после приема первой дозы. Способность тамсулозина воздействовать на α1А подтип адренорецепторов в 20 раз превосходит его способность взаимодействовать с α1В подтипом адренорецепторов, которые расположены в гладких мышцах сосудов. Благодаря такой высокой селективности препарат не вызывает какого-либо клинически значимого снижения системного артериального давления (ЛД) как у пациентов с артериальной гипертензией, так и у пациентов с нормальными показателями артериального давления.\u003Cbr\u003EПри применении тамсулозина в суточной дозе 0,4 мг случаев клинически значимого снижения артериального давления не отмечалось."},{"name":"Фармакологическая группа","value":"альфа1-адреноблокатор"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Пол","value":"для мужчин"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"При температуре не выше 25 °C во вторичной упаковке (пачке картонной).\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"Нет сообщений о случаях острой передозировки тамсулозином.\u003Cbr\u003EСимптомы: снижение артериального давления, компенсаторная тахикардия. Лечение симптоматическое. Артериальное давление и частота сердечных сокращений могут восстановиться при принятии больным горизонтального положения. При отсутствии эффекта можно применить средства, увеличивающие объем циркулирующей крови и, если необходимо, сосудосуживающие средства. Необходимо контролировать функцию почек. Маловероятно, что диализ будет эффективен, так как тамсулозин интенсивно связывается с белками плазмы.\u003Cbr\u003EДля предотвращения дальнейшего всасывания препарата целесообразно промывание желудка, прием активированного угля и осмотических слабительных."},{"name":"Применение при беременности и кормлении грудью","value":"Препарат Тамсулозин Канон предназначен для применения только у лиц мужского пола."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Влияние применения тамсулозина на способность к управлению транспортными средствами и механизмами не изучалось. Тем не менее, в связи с возможным головокружением, следует воздержаться от управления транспортными средствами и механизмами, а также занятием деятельностью, требующей повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"Как и при использовании других α1-адреноблокаторов. при лечении тамсулозином в отдельных случаях может наблюдаться снижение АД, которое иногда может приводить к обморочному состоянию. При первых признаках ортостатической гипотензии (головокружение, слабость) пациент должен сесть или лечь и оставаться в этом положении до тех пор, пока признаки не исчезнут.\u003Cbr\u003EПрежде чем начать терапию тамсулозином, пациент должен быть обследован с тем, чтобы исключить наличие других заболеваний, которые могут вызывать такие же симптомы, как и доброкачественная гиперплазия простаты. Перед началом лечения и регулярно во время терапии должно выполняться пальцевое ректальное обследование и, если требуется, определение простатического специфического антигена (ПСА).\u003Cbr\u003EУ некоторых пациентов при оперативных вмешательствах но поводу катаракты или глаукомы на фоне приема препарата возможно развитие синдрома интраоперационной нестабильности радужной оболочки глаза (синдром узкого зрачка), который может привести к осложнениям во время операции иди в послеоперационном периоде. Целесообразность отмены терапии тамсулозином за 1-2 недели до операции но поводу катаракты или глаукомы не доказана. Случаи интраоперациопиой нестабильности радужной оболочки глаза имели место у пациентов, прекративших прием препарата и в более ранние сроки перед операцией. Не рекомендуется начинать терапию тамсулозином у пациентов, которым запланирована операция но поводу катаракты или глаукомы. Во время предоперационного обследования пациентов хирург и врач-офтальмолог должны учитывать, принимает или принимал ли данный пациент тамсулозин. Эго необходимо для подготовки к возможности развития во время операции интраоперационной нестабильности радужной оболочки глаза.\u003Cbr\u003EВ случае развития ангионевротического отека следует немедленно прекратить терапию препаратом. Повторное назначение тамсулозина противопоказано.\u003Cbr\u003EЛечение тамсулозином пациентов с почечной недостаточностью тяжелой степени (клиренс креатинина менее 10 мл/мин) требует осторожности, т.к. исследований у этой категории пациентов не проводилось.\u003Cbr\u003EПри почечной недостаточности легкой и средней степени тяжести, а также при печеночной недостаточности легкой или средней степени тяжести не требуется коррекция режима дозирования.\u003Cbr\u003EИмеются сообщения о случаях развития длительной эрекции и приапизма на фоне терапии альфа-1-адреноблокаторами. В случае сохранения эрекции до 4- х часов следует немедленно обратиться за медицинской помощью. Если терапия приапизма не была проведена незамедлительно, это может привести к повреждению тканей полового члена и необратимой утрате потенции.\u003Cbr\u003EС осторожностью:\u003Cbr\u003EПочечная недостаточность тяжелой степени (клиренс креатинина менее 10 мл/мин), артериальная гипотензия, при одновременном применении с мощными и средней активности ингибиторами изофермента CYP3A4."},{"name":"Взаимодействие","value":"При совместном применении тамсулозина с атенололом, эналаприлом, нифедипином или теофиллином взаимодействии обнаружено не было.\u003Cbr\u003EПри одновременном применении с циметидином отмечено некоторое повышение концентрации тамсулозина в плазме крови, с фуросемидом - снижение концентрации, однако, это не требует изменения дозы тамсулозина, поскольку концентрация препарата остается в пределах нормального диапазона. Диазепам, пропранолол, трихлорметиазид. хлормадинон, амитриптилин, диклофенак, глибенкламид, симвастатин и варфарин нс изменяют свободную фракцию тамсулозина в плазме человека in vitro. В свою очередь, тамсулозин также не изменяет свободные фракции диазепама, пропранолола, трихлорметиазида и хлормадинона.\u003Cbr\u003EВ исследованиях in vitro не было обнаружено взаимодействия на уровне печеночного метаболизма с амитриптиллином, сальбутамолом, глибенкламидом и финастеридом. Диклофенак и варфарин могут увеличивать с скорость выведения тамсулозина.\u003Cbr\u003EОдновременное применение тамсулозина с мощными ингибиторами изофермента CYP3A4 может привести к увеличению концентрации тамсулозина. Одновременное применение с кетоконазолом (мощный ингибитор изофермента CYP3A4) приводило к увеличению площади под фармакокинетической кривой \"концентрация-время\" (AUC) и максимальной концентрации (Сmах) тамсулозина в 2.8 и 2,2 раза соответственно. Тамсулозин не следует назначать в комбинации с мощными ингибиторами изофермента CYP3A4 у пациентов с нарушением метаболизма изофермента CYP2D6. Препарат следует использовать с осторожностью в комбинации с мощными и средней активности ингибиторами изофермента CYP3A4.\u003Cbr\u003EОдновременное назначение тамсулозина и пароксетина, мощного ингибитора изофермента CYP2D6, приводило к увеличению Сmах и AUC тамсулозина в 1,3 и 1,6 раза, соответственно, однако данное увеличение признано клинически незначимым.\u003Cbr\u003EОдновременное назначение других блокаторов α1-адренорецепторов может привести к гипотензивному эффекту."},{"name":"Регистрационный номер","value":"ЛП-004253"},{"name":"Дата государственной регистрации","value":"10.04.2020"},{"name":"Владелец регистрационного удостоверения","value":"Канонфарма продакшн"},{"name":"Изготовитель","value":"Канонфарма продакшн"},{"name":"Фасовщик","value":"Канонфарма продакшн"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Тамсулозин Канон"},{"name":"Срок годности","value":"24 мес."}]}],"transitionId":"tr_11906915135816096756"}}}}
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Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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383 ₽

  • Завтра, самовывоз • 0 ₽
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    Цена 615 ₽
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  • Тамсулозин Канон капс. кш/раств. с пролонг. высвоб., 0.4 мг, 30 шт.
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    Тамсулозин Канон капс. кш/раств. с пролонг. высвоб., 0.4 мг, 30 шт.

    Рейтинг товара: 4.6 из 5
    на основе 21 оценка
    Цена 403 ₽
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  • Профлосин капс. кш/раств. пролонг. действ., 0.4 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-jxjmolzsi9/toggleWishlist":{"skuId":"228064684","productId":1430912453,"offerId":"bmF4SgwlMFX9L1HSOD5k4g","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQzv6nksSfwJ99EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIxfunqgUQrPvfbBinqtkHIO7cwQc=","sign":"2kidfXGy5w/ts3dUijhrpiYUOC8tbEkcfU1sCUwqksI="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-jxjmolzsi9/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Профлосин капс. кш/раств. пролонг. действ., 0.4 мг, 30 шт.

    Рейтинг товара: 4.8 из 5
    на основе 19 оценок
    Цена 431 ₽
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  • Омник капс. с модиф. высвоб., 0.4 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-rfw49nj0q79/toggleWishlist":{"skuId":"228063055","productId":1430912492,"offerId":"PxRg9ZzltqFbGPXuEVZv6w","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQzv6nksSfwJ99EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI7PunqgUQz+7fbBiS4NAHIO7cwQc=","sign":"Sj2vJdFrobQV6KlgP7LKSOb40KHuFHJba1jTVHUn5WY="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-rfw49nj0q79/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Омник капс. с модиф. высвоб., 0.4 мг, 30 шт.

    Рейтинг товара: 4.6 из 5
    на основе 24 оценки
    Цена 800 ₽
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  • Омник окас таб. контр. высвоб. п/о, 0.4 мг, 30 шт.
    –19 %
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    Омник окас таб. контр. высвоб. п/о, 0.4 мг, 30 шт.

    Рейтинг товара: 4.6 из 5
    на основе 14 оценок
    Цена 826 ₽ вместо 1 024
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  • Тамсулозин-Вертекс таб. пролонг. высвоб. п/о плен., 0.4 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-69a19az1wis/toggleWishlist":{"skuId":"826827025","productId":1778176037,"offerId":"p36ralLCVzY3OBoYMIANew","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQzv6nksSfwJ99EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYIpaDzzwYQkcKhigMYtNWHBCDu3MEH","sign":"2KFSuKcgX9QGgT1ze1QR7akyWWXmBU4uK/1NIFnVh74="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-69a19az1wis/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Тамсулозин-Вертекс таб. пролонг. высвоб. п/о плен., 0.4 мг, 30 шт.

    Рейтинг товара: 4.9 из 5
    на основе 19 оценок
    Цена 445 ₽
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  • Глансин капс. модиф. высвоб., 0.2 мг, 30 шт.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-prh42afqvos/toggleWishlist":{"skuId":"648660718","productId":1430912577,"offerId":"-jS37YIvwZNOQGv4ICdo7w","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQzv6nksSfwJ99EjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYIwfynqgUQ7o2ntQIYxeXQByDu3MEH","sign":"qNFxpKEcisF2SM9/OrawCnwfIayDqLWZZL0B3aJ81xk="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-prh42afqvos/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Глансин капс. модиф. высвоб., 0.2 мг, 30 шт.

    Рейтинг товара: 4.8 из 5
    на основе 6 оценок
    Цена 342 ₽
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  • Тамсулозин ретард таб. таб. пролонг. действ., 0.4 мг, 30 шт.
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    Тамсулозин ретард таб. таб. пролонг. действ., 0.4 мг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 687 ₽
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  • Тамсулозин Реневал капс. киш./раств. пролонг. высв., 400 мкг, 30 шт.
    –11 %
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    Тамсулозин Реневал капс. киш./раств. пролонг. высв., 400 мкг, 30 шт.

    Рейтинг товара: 5 из 5
    на основе 10 оценок
    Цена 406 ₽ вместо 456
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  • ТАМСУЛОЗИН капс. с пролонг. высвоб., 0.4 мг, 30 шт.
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    ТАМСУЛОЗИН капс. с пролонг. высвоб., 0.4 мг, 30 шт.

    Рейтинг товара: 4.3 из 5
    на основе 15 оценок
    Цена 549 ₽
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  • Омник капс. с модиф. высвоб., 0.4 мг, 30 шт.
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    Омник капс. с модиф. высвоб., 0.4 мг, 30 шт.

    Рейтинг товара: 4.8 из 5
    на основе 29 оценок
    Цена 760 ₽
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  • Тамсулозин-obl капс. модиф. высвоб., 0.4 мг, 30 шт.
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    Тамсулозин-obl капс. модиф. высвоб., 0.4 мг, 30 шт.

    Рейтинг товара: 3 из 5
    на основе 2 оценки
    Цена 621 ₽
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Инструкция

Показания к применению

Лечение дизурических расстройств при доброкачественной гиперплазии предстательной железы.

Противопоказания

- Гиперчувствительность к тамсулозину (включая ангионевротический отек) и/или к любому вспомогательному веществу в составе препарата;
- ортостатическая гипотензия (в т. ч. в анамнезе);
- печеночная недостаточность тяжелой степени;
- возраст до 18 лет;
- дефицит лактазы, непереносимость лактозы, синдром глюкозогалактозной мальабсорбции.

Способ применения и дозы

Внутрь, по 1 таблетке (0,4 мг) 1 раз в сутки независимо от приема пищи. Длительность применения не ограничена, препарат назначают в виде непрерывной терапии.
Таблетка должна быть принята целиком, ее нельзя разжевывать, так как это может повлиять на скорость высвобождения препарата.
Синдром отмены отсутствует.
Полная инструкция
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Тамсулозин Канон таб. пролонг. высвоб. п/о плен. плён.
Тамсулозин Канон таб. пролонг. высвоб. п/о плен. плён., 0.4 мг, 30 шт.
4.8
(28)
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1 вопрос
Инструкция

383 ₽

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4.8
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У продавца:28 оценок·5 отзывов
У всех продавцов:35 оценок·5 отзывов
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user avatar
4 месяца назад • елена рыкунова • Куплен на Маркете
Достоинства: Помогает от простатита
Недостатки: Падает давление
Комментарий: Врач рекомендовал пить постоянно
user avatar
3 месяца назад • юрий калинин • Куплен на Маркете
Достоинства: Доступная цена, выполняет функции лекарства
user avatar
8 месяцев назад • Имя скрыто • Куплен на Маркете
Достоинства: помогает
Недостатки: снижает давление когда не надо но не каждый раз
Комментарий: хорошее средство
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    Таблетница из 14 секций на семь дней Утро-вечер

    Цена 167 ₽ вместо 200
  • Таблетница органайзер на неделю, контейнер для таблеток, бокс, на 7 дней, 4 приема, 28 ячеек
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    Таблетница органайзер на неделю, контейнер для таблеток, бокс, на 7 дней, 4 приема, 28 ячеек

    Цена 361 ₽ вместо 690
  • Омник капс. с модиф. высвоб., 0.4 мг, 30 шт.
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    Омник капс. с модиф. высвоб., 0.4 мг, 30 шт.

    Цена 800 ₽
  • Таблетница - брелок на день, 1 раздел, контейнер для таблеток металлический маленький (черный матовый)
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    Таблетница - брелок на день, 1 раздел, контейнер для таблеток металлический маленький (черный матовый)

    Цена 223 ₽ вместо 599
  • Омник окас таб. контр. высвоб. п/о, 0.4 мг, 30 шт.
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    Омник окас таб. контр. высвоб. п/о, 0.4 мг, 30 шт.

    Цена 826 ₽ вместо 1 024
  • Реклама
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  • Таблетница органайзер на неделю утро / день / вечер; Органайзер для таблеток на 7 дней; Карманная аптечка
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    Таблетница органайзер на неделю утро / день / вечер; Органайзер для таблеток на 7 дней; Карманная аптечка

    Цена 773 ₽ вместо 1 890
  • Тамсулозин-Вертекс таб. пролонг. высвоб. п/о плен., 0.4 мг, 30 шт.
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    Тамсулозин-Вертекс таб. пролонг. высвоб. п/о плен., 0.4 мг, 30 шт.

    Цена 445 ₽
  • Таблетница на 7 дней / органайзер / бокс / контейнер на неделю для хранения таблеток и лекарств 4 приема Clear Daswerk
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    Таблетница на 7 дней / органайзер / бокс / контейнер на неделю для хранения таблеток и лекарств 4 приема Clear Daswerk

    Цена 418 ₽ вместо 637
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    Таблетница компактная /органайзер аптечка/ контейнер для таблеток БАД Panda_Home (синего цвета)

    Цена 245 ₽ вместо 263
  • Глансин капс. модиф. высвоб., 0.2 мг, 30 шт.
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    Глансин капс. модиф. высвоб., 0.2 мг, 30 шт.

    Цена 342 ₽
  • Тамсулозин ретард таб. таб. пролонг. действ., 0.4 мг, 30 шт.
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    Тамсулозин ретард таб. таб. пролонг. действ., 0.4 мг, 30 шт.

    Цена 687 ₽
  • Таблетница пенал - органайзер ABORNS на неделю 7 ячеек 7 дней
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    Таблетница пенал - органайзер ABORNS на неделю 7 ячеек 7 дней

    Цена 206 ₽ вместо 350
  • Контейнер для хранения/таблетница/кейс для таблеток
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    Контейнер для хранения/таблетница/кейс для таблеток

    Цена 365 ₽ вместо 699
  • Таблетница Органайзер на 7 дней с делениями x1
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    Таблетница Органайзер на 7 дней с делениями x1

    Цена 180 ₽ вместо 184
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    Тамсулозин Реневал капс. киш./раств. пролонг. высв., 400 мкг, 30 шт.

    Цена 406 ₽ вместо 456
  • Таблетница пенал - органайзер ABORNS на неделю 7 ячеек 7 дней
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    Таблетница пенал - органайзер ABORNS на неделю 7 ячеек 7 дней

    Цена 176 ₽ вместо 400
  • ТАМСУЛОЗИН капс. с пролонг. высвоб., 0.4 мг, 30 шт.
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    ТАМСУЛОЗИН капс. с пролонг. высвоб., 0.4 мг, 30 шт.

    Цена 549 ₽
  • Реклама
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  • Медхелп Таблетница домашняя 28 отделений
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    Медхелп Таблетница домашняя 28 отделений

    Цена 408 ₽
  • Омник капс. с модиф. высвоб., 0.4 мг, 30 шт.
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    Омник капс. с модиф. высвоб., 0.4 мг, 30 шт.

    Цена 760 ₽
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