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Описание

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Трусопт гл. капли, 20 мг/мл, 5 мл

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4.5
(2)
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Коротко о товаре

Артикул Маркета
3124102725
Тип препарата
Назначение
Действующее вещество
Форма выпуска
капли
Инструкция
{"widgets":{"@card/SpecsList":{"/content/page/fancyPage/productSpecsList":{"wrapperProps":{"margins":{"top":4,"bottom":4}},"specsLimit":5,"title":"Коротко о товаре","titleSize":"14","type":"minimal","offset":"s","isHealthCategory":true,"forceShowWidget":true,"withFridge":true}}},"meta":{"/content/page/fancyPage/productSpecsList":{"name":"@card/SpecsList"}},"collections":{"minimalSpecs":{"8235552862233888839":{"specItems":[{"name":"Артикул Маркета","value":"3124102725","withCopyValueButton":true},{"name":"тип препарата","value":"рецептурный лекарственный препарат","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-glaz-i-ushei","categoryId":"15756892","navnodeId":"72496","glfilters":["27272850:1,0","34324371:35649313"]}}},{"name":"назначение","value":"глаукома, открытоугольная глаукома, офтальмогипертензия","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-glaz-i-ushei","categoryId":"15756892","navnodeId":"72496","glfilters":["36476390:36618538,36617871,36617324"]}}},{"name":"действующее вещество","value":"Дорзоламид","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-glaz-i-ushei","categoryId":"15756892","navnodeId":"72496","glfilters":["27144131:28710372"]}}},{"name":"форма выпуска","value":"капли"},{"name":"страна-производитель","value":"Франция"}]}},"compactSpecs":{"8235552862233888839":{"specItems":[{"name":"Артикул Маркета","value":"3124102725","withCopyValueButton":true},{"name":"Тип препарата","value":"Рецептурный лекарственный препарат","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-glaz-i-ushei","categoryId":"15756892","navnodeId":"72496","glfilters":["27272850:1,0","34324371:35649313"]}}},{"name":"Действующее вещество","value":"Дорзоламид","transition":{"type":"list","params":{"categorySlug":"sredstva-dlia-glaz-i-ushei","categoryId":"15756892","navnodeId":"72496","glfilters":["27144131:28710372"]}}},{"name":"Форма выпуска","value":"Капли"},{"name":"Страна-производитель","value":"Франция"}]}},"fullSpecs":{"8235552862233888839":{"specItems":[{"name":"Тип препарата","value":"лекарственный препарат","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-glaz-i-ushei","categoryId":"15756892","navnodeId":"72496","glfilters":["34324371:35649313"]}}},{"name":"Рецептурный препарат","value":"да","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-glaz-i-ushei","categoryId":"15756892","navnodeId":"72496","glfilters":["27272850:1,0"]}}},{"name":"Органы и системы","value":"глаза","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-glaz-i-ushei","categoryId":"15756892","navnodeId":"72496","glfilters":["34045610:34516019"]}}},{"name":"Назначение","value":"глаукома, открытоугольная глаукома, офтальмогипертензия","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-glaz-i-ushei","categoryId":"15756892","navnodeId":"72496","glfilters":["36476390:36618538,36617871,36617324"]}}},{"name":"Показания к применению","value":"Препарат Трусопт назначается взрослым пациентам с:\u003Cbr\u003E- офтальмогипертензией;\u003Cbr\u003E- первичной открытоугольной глаукомой;\u003Cbr\u003E- псевдоэксфолиативной глаукомой;\u003Cbr\u003E- вторичной глаукомой (без блока угла передней камеры глаза).\u003Cbr\u003EПрепарат Трусопт назначается детям:\u003Cbr\u003E- для лечения глаукомы у детей с 1 недели в режиме монотерапии или в качестве дополнения к лечению бета-адреноблокаторами."},{"name":"Противопоказания","value":"-повышенная чувствительность к действующему веществу или любому из вспомогательных веществ;\u003Cbr\u003E\n-тяжелая почечная недостаточность;\u003Cbr\u003E\n-гиперхлоремический ацидоз;\u003Cbr\u003E\n-беременность;\u003Cbr\u003E\n-период грудного вскармливания;\u003Cbr\u003E\n-дети младше 1 недели.\u003Cbr\u003E"},{"name":"Состав","value":"1 мл препарата содержит:\u003Cbr\u003Eактивное вещество: дорзоламида гидрохлорида 22,26 мг (эквивалент 20 мг дорзоламида);\u003Cbr\u003Eвспомогательные вещества: маннитол 23,00 мг, гиэтеллоза 4,75 мг, натрия цитрат 2,94 мг, бензалкония хлорид 0,075 мг, натрия гидроксид для коррекции pH 5,5-5,8, вода для инъекций до 1 мл."},{"name":"Действующее вещество","value":"Дорзоламид","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-glaz-i-ushei","categoryId":"15756892","navnodeId":"72496","glfilters":["27144131:28710372"]}}},{"name":"Способ применения и дозы","value":"Режим дозирования\u003Cbr\u003E\nПри применении в качестве монотерапии по одной капле препарата Трусопт в конъюнктивальный мешок пораженных(ого) глаз(а) три раза в сутки. При применении в качестве дополнительной терапии к офтальмологическому бета-блокатору по одной капле препарата Трусопт в конъюнктивальный мешок пораженных(ого) глаз(а) два раза в сутки.\u003Cbr\u003E\nПри замене какого-либо противоглаукомного препарата на препарат Трусопт следует начать лечение препаратом Трусопт со следующего дня после отмены предыдущего препарата.\u003Cbr\u003E\nПри совместном применении препарата Трусопт с другими препаратами для местного применения в офтальмологии следует соблюдать интервал между их инстилляциями не менее 10 минут.\u003Cbr\u003E\nПациентов следует предупредить о необходимости вымыть руки перед использованием и не допускать контакта флакона с глазом или окружающими тканями.\u003Cbr\u003E\nПациентов также следует предупредить, что при неправильном применении растворы для местного применения в офтальмологии могут быть контаминированы бактериями, способными вызывать инфекционные заболевания глаз. Использование контаминированных глазных капель может привести к серьезному повреждению глаз и последующей потере зрения.\u003Cbr\u003E\nПациенты должны быть проинформированы о правильном обращении с флаконом для многократного применения.\u003Cbr\u003E\nДети\u003Cbr\u003E\nХотя имеются ограниченные клинические данные по применению дорзоламида у пациентов детского возраста три раза в сутки, режим дозирования для детей такой же, как и для взрослых."},{"name":"Побочные действия","value":"В клинических исследованиях Трусопт назначался 1108 пациентам в качестве монотерапии или дополнительной терапии к лечению бета-адреноблокаторами. Приблизительно у 3% пациентов препарат был отменен в связи с местными побочными реакциями со стороны глаза, наиболее частыми из них были конъюнктивиты и реакции со стороны век.\u003Cbr\u003EПобочные эффекты, зарегистрированные в ходе исследований и в ходе пострегистрационного периода, классифицированы по частоте (очень частые (≥1/10), частые (≥1/100, \u003C1/10); нечастые (≥1/1000, \u003C1/100); редкие (≥1/10000, \u003C1/1000)).\u003Cbr\u003EСо стороны нервной системы\u003Cbr\u003EЧасто: головная боль.\u003Cbr\u003EРедко: головокружение, парестезии.\u003Cbr\u003EСо стороны органа зрения\u003Cbr\u003EОчень часто: жжение и боль.\u003Cbr\u003EЧасто: поверхностный точечный кератит, слезотечение, конъюнктивит, воспаление век, зуд, раздражение века, нечеткость зрения.\u003Cbr\u003EНечасто: иридоциклит.\u003Cbr\u003EРедко: покраснение глаз, боль, гиперкератоз век, транзиторная миопия (исчезающая после отмены препарата), отек роговицы, снижение внутриглазного давления, отслойка хориоидальной оболочки глаза после хирургических вмешательств по восстановлению оттока внутриглазной жидкости.\u003Cbr\u003EСо стороны органов дыхания, грудной клетки и средостения\u003Cbr\u003EРедко: носовые кровотечения.\u003Cbr\u003EСо стороны желудочно-кишечного тракта\u003Cbr\u003EЧасто: тошнота, горький привкус во рту.\u003Cbr\u003EРедко: фарингит, сухость во рту.\u003Cbr\u003EСо стороны кожи и слизистых оболочек\u003Cbr\u003EРедко: контактный дерматит, синдром Стивенса-Джонсона и токсический эпидермальный некролиз.\u003Cbr\u003EСо стороны мочевыводящих путей\u003Cbr\u003EРедко: уролитиаз.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения\u003Cbr\u003EЧасто: астения, усталость.\u003Cbr\u003EРедко: аллергические реакции - признаки и симптомы местных реакций (со стороны век) и системные аллергические реакции, включающие ангионевротический отек, крапивницу, зуд, сыпь, затруднение дыхания, реже - бронхоспазм.\u003Cbr\u003EДети\u003Cbr\u003EВ ходе 3-месячного двойного слепого мультицентрового исследования с использованием активного препарата в качестве контроля, проводимого с участием 184 детей в возрасте младше 6 лет, профиль побочных реакций препарата Трусопт был сопоставим с профилем побочных реакций у взрослых пациентов. Наиболее частыми побочными реакциями, связанными с применением препарата Трусопт, у детей в возрасте младше 2 лет были конъюнктивальная инъекция (5,4%) и выделения из глаз (3,6%). У детей от 2 до 6 лет наиболее частыми побочными реакциями были чувство жжения в глазу (12,1%), конъюнктивальная инъекция (7,6%), боль в глазу (3%), воспаление век (3%)."},{"name":"Фармакологическое действие","value":"В состав препарата Трусопт входит ингибитор карбоангидразы II - дорзоламида гидрохлорид. Ингибирование карбоангидразы (КА) в цилиарном теле глазного яблока снижает продукцию внутриглазной жидкости, предположительно, благодаря замедлению синтеза ионов бикарбоната с их последующим восстановлением до натрия и выведением жидкости. В результате этого происходит снижение внутриглазного давления (ВГД)."},{"name":"Фармакологическая группа","value":"противоглаукомный препарат, ингибитор карбоангидразы"},{"name":"Форма выпуска","value":"капли"},{"name":"Способ применения/введения","value":"конъюктивальный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-glaz-i-ushei","categoryId":"15756892","navnodeId":"72496","glfilters":["35947170:36763746"]}}},{"name":"Условия хранения","value":"Хранить при температуре не выше 30 °С, в защищенном от света месте.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"Возможны электролитные нарушения, развитие метаболического ацидоза и возникновение сонливости, тошноты, головокружения, головной боли, слабости, необычных сновидений, дисфагии. Следует контролировать плазменные концентрации электролитов (особенно калия) и значения pH крови.\u003Cbr\u003EВ случае передозировки проводится симптоматическая терапия, направленная на поддержание жизненно важных функций организма."},{"name":"Применение при беременности и кормлении грудью","value":"Беременность\u003Cbr\u003E\nДорзоламид не следует применять во время беременности. Данные о применении дорзоламида у беременных женщин отсутствуют или ограничены. У кроликов дорзоламид вызывал тератогенный эффект при дозах, токсичных для беременных самок.\u003Cbr\u003E\nПериод грудного вскармливания\u003Cbr\u003E\nНеизвестно, экскретируется ли дорзоламид или его метаболиты в грудное молоко. Доступные данные по фармакодинамике/токсикологии, полученные в исследованиях на животных, говорят о том, что его метаболиты выделяются в грудное молоко. Принимая во внимание пользу грудного вскармливания для ребенка и пользу терапии для женщины, необходимо принять решение о том, следует ли прекратить грудное вскармливание или прекратить/воздержаться от терапии препаратом Трусопт. Риск для новорожденных/младенцев также не может быть исключен.\u003Cbr\u003E\nФертильность\u003Cbr\u003E\nДанные, полученные в ходе исследований на животных, не предполагают влияния терапии дорзоламидом на фертильность самцов и самок. Данные исследований на людях отсутствуют."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Исследований влияния препарата на способность к управлению транспортными средствами и работе с механизмами не проводилось. Тем не менее, возможные побочные реакции, такие как головокружение и нарушения зрения, могут повлиять на способность управлять транспортным средством и/или работать с механизмами."},{"name":"Особые указания","value":"Применение дорзоламида у пациентов с острой закрытоугольной глаукомой не изучалось. Лечение пациентов с острой закрытоугольной глаукомой требует неотложных лечебных мероприятий в дополнение к местным офтальмологическим гипотензивным средствам.\u003Cbr\u003E\nДорзоламид содержит сульфонамидную группу, которая также встречается в сульфаниламидах, и, хотя препарат применяется местно, он абсорбируется и в системный кровоток. Таким образом, при местном применении могут возникать такие же типы побочных реакций, которые были обнаружены при системном введении сульфаниламидов, включая такие тяжелые реакции, как синдром Стивенса-Джонсона и токсический эпидермальный некролиз. При появлении признаков серьезных реакций или реакций гиперчувствительности следует прекратить использование этого препарата.\u003Cbr\u003E\nЛечение пероральными ингибиторами карбоангидразы связано с развитием мочекаменной болезни вследствие нарушения кислотно-щелочного баланса, особенно у пациентов с камнями почек в анамнезе. Несмотря на то, что при применении дорзоламида нарушений кислотно-щелочного баланса не наблюдалось, были редкие сообщения о случаях мочекаменной болезни. Поскольку дорзоламид содержит ингибитор карбоангидразы для местного применения в офтальмологии, который абсорбируется в системный кровоток, у пациентов с камнями мочевыводящих путей в анамнезе может повышаться риск развития мочекаменной болезни при применении этого лекарственного препарата.\u003Cbr\u003E\nПри появлении аллергических реакций (например, конъюнктивит и реакции со стороны век) следует рассмотреть возможность прекращения использования препарата.\u003Cbr\u003E\nИмеется вероятность аддитивного эффекта в отношении известных системных эффектов ингибирования карбоангидразы у пациентов, получающих пероральный ингибитор карбоангидразы и дорзоламид. Одновременное применение дорзоламида и пероральных ингибиторов карбоангидразы не рекомендуется.\u003Cbr\u003E\nСообщалось об отеке роговицы и необратимой декомпенсации роговицы при применении дорзоламида у пациентов с ранее имевшимися рецидивирующими эрозиями роговицы и/или которым проводили хирургическое вмешательство с нарушением целостности глазного яблока. Вероятность развития отека роговицы также повышается. Следует соблюдать меры предосторожности при назначении препарата Трусопт этим группам пациентов.\u003Cbr\u003E\nСообщалось об отслойке сосудистой оболочки глаза, сопровождающейся гипотонией глаза, в случае применения растворов офтальмологических препаратов, снижающих секрецию водянистой влаги после оперативных вмешательств по восстановлению оттока внутриглазной жидкости.\u003Cbr\u003E\nДорзоламид не изучался у пациентов с тяжелой почечной недостаточностью (клиренс креатинина \u003C30 мл/мин) или с гиперхлоремическим ацидозом. Поскольку дорзоламид и его метаболиты выводятся преимущественно почками, дорзоламид противопоказан таким пациентам.\u003Cbr\u003E\nВ состав препарата Трусопт входит консервант бензалкония хлорид, который может вызывать раздражение глаза. У пациентов с заболеванием роговицы и синдромом «сухого» глаза при применении препарата, содержащего бензалкония хлорид в качестве консерванта возможно развитие язвенной токсической кератопатии или точечной кератопатии. При длительной терапии препаратом Трусопт у таких пациентов, необходимо контролировать состояние роговицы.\u003Cbr\u003E\nПеред применением препарата контактные линзы необходимо снять и вновь надеть их не ранее, чем через 15 минут после закапывания. Бензалкония хлорид способен обесцвечивать мягкие контактные линзы.\u003Cbr\u003E\nПрименение у детей\u003Cbr\u003E\nДорзоламид не изучался у пациентов с гестационным возрастом менее 36 недель и возрастом менее 1 недели. Пациенты со значительной незрелостью почечных канальцев могут получать дорзоламид только после тщательной оценки соотношения пользы и рисков, связанных с вероятным риском метаболического ацидоза."},{"name":"Взаимодействие","value":"Специальных исследований по изучению взаимодействия препарата Трусопт с другими лекарственными препаратами не проводилось. В клинических исследованиях препарата Трусопт назначали в комбинации с другими лекарственными препаратами без отрицательных проявлений межлекарственного взаимодействия, в том числе: с глазными каплями тимолола и бетаксолола, а также системными препаратами: ингибиторами АПФ, блокаторами кальциевых каналов, диуретиками, нестероидными противовоспалительными препаратами (включая ацетилсалициловую кислоту), гормонами (эстрогеном, инсулином, тироксином).\u003Cbr\u003EНе исключается возможность взаимного усиления системных эффектов ингибиторов карбоангидразы для внутреннего применения и препарата Трусопт при их одновременном использовании. Комбинированное лечение с препаратами, оказывающими системное действие, и местными ингибиторами карбоангидразы (препаратом Трусопт) в клинических исследованиях не изучалось.\u003Cbr\u003EПрепарат Трусопт является ингибитором карбоангидразы и, хотя применяется местно, частично всасывается и может оказывать системное действие.\u003Cbr\u003EВ клинических исследованиях применение препарата Трусопт не сопровождалось нарушением кислотно-щелочного баланса. Однако подобные явления наблюдали при применении ингибиторов карбоангидразы, в том числе и в результате межлекарственного взаимодействия с другими препаратами (как проявление токсичности на фоне приема высоких доз салицилатов). Таким образом, при назначении препарата Трусопт не следует забывать о возможности подобных межлекарственных взаимодействий.\u003Cbr\u003EПациент должен сообщить врачу обо всех лекарственных препаратах, которые он применяет или планирует применять, включая те, которые продаются без рецепта.\u003Cbr\u003EСледует обратить особое внимание на прием высоких доз ацетилсалициловой кислоты."},{"name":"Регистрационный номер","value":"П N013715/01"},{"name":"Дата государственной регистрации","value":"08.02.2021"},{"name":"Владелец регистрационного удостоверения","value":"Santen","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-glaz-i-ushei","categoryId":"15756892","navnodeId":"72496","glfilters":["34324371:35649313","7893318:16003075"]}}},{"name":"Изготовитель","value":"MSD"},{"name":"Фасовщик","value":"MSD"},{"name":"Страна бренда","value":"Финляндия"},{"name":"Страна-производитель","value":"Франция"},{"name":"Название препарата","value":"Трусопт","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-glaz-i-ushei","categoryId":"15756892","navnodeId":"72496","glfilters":["17796364:18046438"]}}},{"name":"Срок годности","value":"1 г."}]}},"fullSpecsGrouped":{"8235552862233888839":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"глаза"},{"name":"Назначение","value":"глаукома, открытоугольная глаукома, офтальмогипертензия"},{"name":"Показания к применению","value":"Препарат Трусопт назначается взрослым пациентам с:\u003Cbr\u003E- офтальмогипертензией;\u003Cbr\u003E- первичной открытоугольной глаукомой;\u003Cbr\u003E- псевдоэксфолиативной глаукомой;\u003Cbr\u003E- вторичной глаукомой (без блока угла передней камеры глаза).\u003Cbr\u003EПрепарат Трусопт назначается детям:\u003Cbr\u003E- для лечения глаукомы у детей с 1 недели в режиме монотерапии или в качестве дополнения к лечению бета-адреноблокаторами."},{"name":"Противопоказания","value":"-повышенная чувствительность к действующему веществу или любому из вспомогательных веществ;\u003Cbr\u003E\n-тяжелая почечная недостаточность;\u003Cbr\u003E\n-гиперхлоремический ацидоз;\u003Cbr\u003E\n-беременность;\u003Cbr\u003E\n-период грудного вскармливания;\u003Cbr\u003E\n-дети младше 1 недели.\u003Cbr\u003E"},{"name":"Состав","value":"1 мл препарата содержит:\u003Cbr\u003Eактивное вещество: дорзоламида гидрохлорида 22,26 мг (эквивалент 20 мг дорзоламида);\u003Cbr\u003Eвспомогательные вещества: маннитол 23,00 мг, гиэтеллоза 4,75 мг, натрия цитрат 2,94 мг, бензалкония хлорид 0,075 мг, натрия гидроксид для коррекции pH 5,5-5,8, вода для инъекций до 1 мл."},{"name":"Действующее вещество","value":"Дорзоламид"},{"name":"Способ применения и дозы","value":"Режим дозирования\u003Cbr\u003E\nПри применении в качестве монотерапии по одной капле препарата Трусопт в конъюнктивальный мешок пораженных(ого) глаз(а) три раза в сутки. При применении в качестве дополнительной терапии к офтальмологическому бета-блокатору по одной капле препарата Трусопт в конъюнктивальный мешок пораженных(ого) глаз(а) два раза в сутки.\u003Cbr\u003E\nПри замене какого-либо противоглаукомного препарата на препарат Трусопт следует начать лечение препаратом Трусопт со следующего дня после отмены предыдущего препарата.\u003Cbr\u003E\nПри совместном применении препарата Трусопт с другими препаратами для местного применения в офтальмологии следует соблюдать интервал между их инстилляциями не менее 10 минут.\u003Cbr\u003E\nПациентов следует предупредить о необходимости вымыть руки перед использованием и не допускать контакта флакона с глазом или окружающими тканями.\u003Cbr\u003E\nПациентов также следует предупредить, что при неправильном применении растворы для местного применения в офтальмологии могут быть контаминированы бактериями, способными вызывать инфекционные заболевания глаз. Использование контаминированных глазных капель может привести к серьезному повреждению глаз и последующей потере зрения.\u003Cbr\u003E\nПациенты должны быть проинформированы о правильном обращении с флаконом для многократного применения.\u003Cbr\u003E\nДети\u003Cbr\u003E\nХотя имеются ограниченные клинические данные по применению дорзоламида у пациентов детского возраста три раза в сутки, режим дозирования для детей такой же, как и для взрослых."},{"name":"Побочные действия","value":"В клинических исследованиях Трусопт назначался 1108 пациентам в качестве монотерапии или дополнительной терапии к лечению бета-адреноблокаторами. Приблизительно у 3% пациентов препарат был отменен в связи с местными побочными реакциями со стороны глаза, наиболее частыми из них были конъюнктивиты и реакции со стороны век.\u003Cbr\u003EПобочные эффекты, зарегистрированные в ходе исследований и в ходе пострегистрационного периода, классифицированы по частоте (очень частые (≥1/10), частые (≥1/100, \u003C1/10); нечастые (≥1/1000, \u003C1/100); редкие (≥1/10000, \u003C1/1000)).\u003Cbr\u003EСо стороны нервной системы\u003Cbr\u003EЧасто: головная боль.\u003Cbr\u003EРедко: головокружение, парестезии.\u003Cbr\u003EСо стороны органа зрения\u003Cbr\u003EОчень часто: жжение и боль.\u003Cbr\u003EЧасто: поверхностный точечный кератит, слезотечение, конъюнктивит, воспаление век, зуд, раздражение века, нечеткость зрения.\u003Cbr\u003EНечасто: иридоциклит.\u003Cbr\u003EРедко: покраснение глаз, боль, гиперкератоз век, транзиторная миопия (исчезающая после отмены препарата), отек роговицы, снижение внутриглазного давления, отслойка хориоидальной оболочки глаза после хирургических вмешательств по восстановлению оттока внутриглазной жидкости.\u003Cbr\u003EСо стороны органов дыхания, грудной клетки и средостения\u003Cbr\u003EРедко: носовые кровотечения.\u003Cbr\u003EСо стороны желудочно-кишечного тракта\u003Cbr\u003EЧасто: тошнота, горький привкус во рту.\u003Cbr\u003EРедко: фарингит, сухость во рту.\u003Cbr\u003EСо стороны кожи и слизистых оболочек\u003Cbr\u003EРедко: контактный дерматит, синдром Стивенса-Джонсона и токсический эпидермальный некролиз.\u003Cbr\u003EСо стороны мочевыводящих путей\u003Cbr\u003EРедко: уролитиаз.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения\u003Cbr\u003EЧасто: астения, усталость.\u003Cbr\u003EРедко: аллергические реакции - признаки и симптомы местных реакций (со стороны век) и системные аллергические реакции, включающие ангионевротический отек, крапивницу, зуд, сыпь, затруднение дыхания, реже - бронхоспазм.\u003Cbr\u003EДети\u003Cbr\u003EВ ходе 3-месячного двойного слепого мультицентрового исследования с использованием активного препарата в качестве контроля, проводимого с участием 184 детей в возрасте младше 6 лет, профиль побочных реакций препарата Трусопт был сопоставим с профилем побочных реакций у взрослых пациентов. Наиболее частыми побочными реакциями, связанными с применением препарата Трусопт, у детей в возрасте младше 2 лет были конъюнктивальная инъекция (5,4%) и выделения из глаз (3,6%). У детей от 2 до 6 лет наиболее частыми побочными реакциями были чувство жжения в глазу (12,1%), конъюнктивальная инъекция (7,6%), боль в глазу (3%), воспаление век (3%)."},{"name":"Фармакологическое действие","value":"В состав препарата Трусопт входит ингибитор карбоангидразы II - дорзоламида гидрохлорид. Ингибирование карбоангидразы (КА) в цилиарном теле глазного яблока снижает продукцию внутриглазной жидкости, предположительно, благодаря замедлению синтеза ионов бикарбоната с их последующим восстановлением до натрия и выведением жидкости. В результате этого происходит снижение внутриглазного давления (ВГД)."},{"name":"Фармакологическая группа","value":"противоглаукомный препарат, ингибитор карбоангидразы"},{"name":"Форма выпуска","value":"капли"},{"name":"Способ применения/введения","value":"конъюктивальный"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"Хранить при температуре не выше 30 °С, в защищенном от света месте.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"Возможны электролитные нарушения, развитие метаболического ацидоза и возникновение сонливости, тошноты, головокружения, головной боли, слабости, необычных сновидений, дисфагии. Следует контролировать плазменные концентрации электролитов (особенно калия) и значения pH крови.\u003Cbr\u003EВ случае передозировки проводится симптоматическая терапия, направленная на поддержание жизненно важных функций организма."},{"name":"Применение при беременности и кормлении грудью","value":"Беременность\u003Cbr\u003E\nДорзоламид не следует применять во время беременности. Данные о применении дорзоламида у беременных женщин отсутствуют или ограничены. У кроликов дорзоламид вызывал тератогенный эффект при дозах, токсичных для беременных самок.\u003Cbr\u003E\nПериод грудного вскармливания\u003Cbr\u003E\nНеизвестно, экскретируется ли дорзоламид или его метаболиты в грудное молоко. Доступные данные по фармакодинамике/токсикологии, полученные в исследованиях на животных, говорят о том, что его метаболиты выделяются в грудное молоко. Принимая во внимание пользу грудного вскармливания для ребенка и пользу терапии для женщины, необходимо принять решение о том, следует ли прекратить грудное вскармливание или прекратить/воздержаться от терапии препаратом Трусопт. Риск для новорожденных/младенцев также не может быть исключен.\u003Cbr\u003E\nФертильность\u003Cbr\u003E\nДанные, полученные в ходе исследований на животных, не предполагают влияния терапии дорзоламидом на фертильность самцов и самок. Данные исследований на людях отсутствуют."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Исследований влияния препарата на способность к управлению транспортными средствами и работе с механизмами не проводилось. Тем не менее, возможные побочные реакции, такие как головокружение и нарушения зрения, могут повлиять на способность управлять транспортным средством и/или работать с механизмами."},{"name":"Особые указания","value":"Применение дорзоламида у пациентов с острой закрытоугольной глаукомой не изучалось. Лечение пациентов с острой закрытоугольной глаукомой требует неотложных лечебных мероприятий в дополнение к местным офтальмологическим гипотензивным средствам.\u003Cbr\u003E\nДорзоламид содержит сульфонамидную группу, которая также встречается в сульфаниламидах, и, хотя препарат применяется местно, он абсорбируется и в системный кровоток. Таким образом, при местном применении могут возникать такие же типы побочных реакций, которые были обнаружены при системном введении сульфаниламидов, включая такие тяжелые реакции, как синдром Стивенса-Джонсона и токсический эпидермальный некролиз. При появлении признаков серьезных реакций или реакций гиперчувствительности следует прекратить использование этого препарата.\u003Cbr\u003E\nЛечение пероральными ингибиторами карбоангидразы связано с развитием мочекаменной болезни вследствие нарушения кислотно-щелочного баланса, особенно у пациентов с камнями почек в анамнезе. Несмотря на то, что при применении дорзоламида нарушений кислотно-щелочного баланса не наблюдалось, были редкие сообщения о случаях мочекаменной болезни. Поскольку дорзоламид содержит ингибитор карбоангидразы для местного применения в офтальмологии, который абсорбируется в системный кровоток, у пациентов с камнями мочевыводящих путей в анамнезе может повышаться риск развития мочекаменной болезни при применении этого лекарственного препарата.\u003Cbr\u003E\nПри появлении аллергических реакций (например, конъюнктивит и реакции со стороны век) следует рассмотреть возможность прекращения использования препарата.\u003Cbr\u003E\nИмеется вероятность аддитивного эффекта в отношении известных системных эффектов ингибирования карбоангидразы у пациентов, получающих пероральный ингибитор карбоангидразы и дорзоламид. Одновременное применение дорзоламида и пероральных ингибиторов карбоангидразы не рекомендуется.\u003Cbr\u003E\nСообщалось об отеке роговицы и необратимой декомпенсации роговицы при применении дорзоламида у пациентов с ранее имевшимися рецидивирующими эрозиями роговицы и/или которым проводили хирургическое вмешательство с нарушением целостности глазного яблока. Вероятность развития отека роговицы также повышается. Следует соблюдать меры предосторожности при назначении препарата Трусопт этим группам пациентов.\u003Cbr\u003E\nСообщалось об отслойке сосудистой оболочки глаза, сопровождающейся гипотонией глаза, в случае применения растворов офтальмологических препаратов, снижающих секрецию водянистой влаги после оперативных вмешательств по восстановлению оттока внутриглазной жидкости.\u003Cbr\u003E\nДорзоламид не изучался у пациентов с тяжелой почечной недостаточностью (клиренс креатинина \u003C30 мл/мин) или с гиперхлоремическим ацидозом. Поскольку дорзоламид и его метаболиты выводятся преимущественно почками, дорзоламид противопоказан таким пациентам.\u003Cbr\u003E\nВ состав препарата Трусопт входит консервант бензалкония хлорид, который может вызывать раздражение глаза. У пациентов с заболеванием роговицы и синдромом «сухого» глаза при применении препарата, содержащего бензалкония хлорид в качестве консерванта возможно развитие язвенной токсической кератопатии или точечной кератопатии. При длительной терапии препаратом Трусопт у таких пациентов, необходимо контролировать состояние роговицы.\u003Cbr\u003E\nПеред применением препарата контактные линзы необходимо снять и вновь надеть их не ранее, чем через 15 минут после закапывания. Бензалкония хлорид способен обесцвечивать мягкие контактные линзы.\u003Cbr\u003E\nПрименение у детей\u003Cbr\u003E\nДорзоламид не изучался у пациентов с гестационным возрастом менее 36 недель и возрастом менее 1 недели. Пациенты со значительной незрелостью почечных канальцев могут получать дорзоламид только после тщательной оценки соотношения пользы и рисков, связанных с вероятным риском метаболического ацидоза."},{"name":"Взаимодействие","value":"Специальных исследований по изучению взаимодействия препарата Трусопт с другими лекарственными препаратами не проводилось. В клинических исследованиях препарата Трусопт назначали в комбинации с другими лекарственными препаратами без отрицательных проявлений межлекарственного взаимодействия, в том числе: с глазными каплями тимолола и бетаксолола, а также системными препаратами: ингибиторами АПФ, блокаторами кальциевых каналов, диуретиками, нестероидными противовоспалительными препаратами (включая ацетилсалициловую кислоту), гормонами (эстрогеном, инсулином, тироксином).\u003Cbr\u003EНе исключается возможность взаимного усиления системных эффектов ингибиторов карбоангидразы для внутреннего применения и препарата Трусопт при их одновременном использовании. Комбинированное лечение с препаратами, оказывающими системное действие, и местными ингибиторами карбоангидразы (препаратом Трусопт) в клинических исследованиях не изучалось.\u003Cbr\u003EПрепарат Трусопт является ингибитором карбоангидразы и, хотя применяется местно, частично всасывается и может оказывать системное действие.\u003Cbr\u003EВ клинических исследованиях применение препарата Трусопт не сопровождалось нарушением кислотно-щелочного баланса. Однако подобные явления наблюдали при применении ингибиторов карбоангидразы, в том числе и в результате межлекарственного взаимодействия с другими препаратами (как проявление токсичности на фоне приема высоких доз салицилатов). Таким образом, при назначении препарата Трусопт не следует забывать о возможности подобных межлекарственных взаимодействий.\u003Cbr\u003EПациент должен сообщить врачу обо всех лекарственных препаратах, которые он применяет или планирует применять, включая те, которые продаются без рецепта.\u003Cbr\u003EСледует обратить особое внимание на прием высоких доз ацетилсалициловой кислоты."},{"name":"Регистрационный номер","value":"П N013715/01"},{"name":"Дата государственной регистрации","value":"08.02.2021"},{"name":"Владелец регистрационного удостоверения","value":"Santen"},{"name":"Изготовитель","value":"MSD"},{"name":"Фасовщик","value":"MSD"},{"name":"Страна бренда","value":"Финляндия"},{"name":"Страна-производитель","value":"Франция"},{"name":"Название препарата","value":"Трусопт"},{"name":"Срок годности","value":"1 г."}]}],"transitionId":"tr_6147797558016347006"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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360 ₽

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  • Трусопт гл. капли, 20 мг/мл, 5 мл
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    Трусопт гл. капли, 20 мг/мл, 5 мл

    Рейтинг товара: 4.9 из 5
    на основе 15 оценок
    Цена 312 ₽
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  • Дорзопт гл. капли, 2%, 5 мл, 1 шт.
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    Дорзопт гл. капли, 2%, 5 мл, 1 шт.

    Рейтинг товара: 5 из 5
    на основе 5 оценок
    Цена 338 ₽
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  • Косопт гл. капли фл., 20 мг+5 мг/мл, 5 мл
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    Косопт гл. капли фл., 20 мг+5 мг/мл, 5 мл

    Рейтинг товара: 4.7 из 5
    на основе 7 оценок
    Цена 1 279 ₽
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  • Дорзоламид-Оптик гл. капли фл., 20 мг/мл, 5 мл
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    Дорзоламид-Оптик гл. капли фл., 20 мг/мл, 5 мл

    Рейтинг товара: 4.8 из 5
    на основе 5 оценок
    Цена 317 ₽
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  • Дорзоламид-СЗ гл. капли, 20 мг/мл, 5 мл
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    Дорзоламид-СЗ гл. капли, 20 мг/мл, 5 мл

    Рейтинг товара: 5 из 5
    на основе 2 оценки
    Цена 237 ₽
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  • Дорзолан соло гл. капли, 20 мг/мл, 5 мл, 1 шт.
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    Дорзолан соло гл. капли, 20 мг/мл, 5 мл, 1 шт.

    Рейтинг товара: 4.8 из 5
    на основе 18 оценок
    Цена 309 ₽
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  • Альфаган Р гл.капли фл.-капельница, 0.15%, 5 мл, 1 шт.
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    Альфаган Р гл.капли фл.-капельница, 0.15%, 5 мл, 1 шт.

    Рейтинг товара: 4.6 из 5
    на основе 5 оценок
    Цена 987 ₽
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  • Окупрес-Е гл. капли, 0.25%, 5 мл
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    Окупрес-Е гл. капли, 0.25%, 5 мл

    Рейтинг товара: 5 из 5
    на основе 2 оценки
    Цена 30 ₽
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  • Офтаквикс гл. капли фл.-кап., 5 мл
    –16 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-yi5bhypupbm/toggleWishlist":{"skuId":"1407096962","productId":1778174459,"offerId":"7ZjC_zlVJ-wA4-d4hDVHjg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQtpfnoemnm7UREjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYI+5PzzwYQgrH6ngUYg+DQByDc3MEH","sign":"0teV+3bbYjKl0zKPHFruc1JrGoKAdP1VIMr6Y8q8KK0="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-yi5bhypupbm/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Офтаквикс гл. капли фл.-кап., 5 мл

    Рейтинг товара: 5 из 5
    на основе 4 оценки
    Цена 254 ₽ вместо 304
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  • Тимолол гл. капли, 0.5%, 5 мл, 1 шт.
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    Тимолол гл. капли, 0.5%, 5 мл, 1 шт.

    Рейтинг товара: 5 из 5
    на основе 1 оценка
    Цена 74 ₽
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Инструкция

Показания к применению

Препарат Трусопт назначается взрослым пациентам с:
- офтальмогипертензией;
- первичной открытоугольной глаукомой;
- псевдоэксфолиативной глаукомой;
- вторичной глаукомой (без блока угла передней камеры глаза).
Препарат Трусопт назначается детям:
- для лечения глаукомы у детей с 1 недели в режиме монотерапии или в качестве дополнения к лечению бета-адреноблокаторами.

Противопоказания

-повышенная чувствительность к действующему веществу или любому из вспомогательных веществ;
-тяжелая почечная недостаточность;
-гиперхлоремический ацидоз;
-беременность;
-период грудного вскармливания;
-дети младше 1 недели.

Способ применения и дозы

Режим дозирования
При применении в качестве монотерапии по одной капле препарата Трусопт в конъюнктивальный мешок пораженных(ого) глаз(а) три раза в сутки. При применении в качестве дополнительной терапии к офтальмологическому бета-блокатору по одной капле препарата Трусопт в конъюнктивальный мешок пораженных(ого) глаз(а) два раза в сутки.
При замене какого-либо противоглаукомного препарата на препарат Трусопт следует начать лечение препаратом Трусопт со следующего дня после отмены предыдущего препарата.
При совместном применении препарата Трусопт с другими препаратами для местного применения в офтальмологии следует соблюдать интервал между их инстилляциями не менее 10 минут.
Пациентов следует предупредить о необходимости вымыть руки перед использованием и не допускать контакта флакона с глазом или окружающими тканями.
Пациентов также следует предупредить, что при неправильном применении растворы для местного применения в офтальмологии могут быть контаминированы бактериями, способными вызывать инфекционные заболевания глаз. Использование контаминированных глазных капель может привести к серьезному повреждению глаз и последующей потере зрения.
Пациенты должны быть проинформированы о правильном обращении с флаконом для многократного применения.
Дети
Хотя имеются ограниченные клинические данные по применению дорзоламида у пациентов детского возраста три раза в сутки, режим дозирования для детей такой же, как и для взрослых.
Полная инструкция
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Трусопт гл. капли
Трусопт гл. капли, 20 мг/мл, 5 мл
4.5
(2)
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Задать вопрос
Инструкция

360 ₽

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4.5
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У продавца:2 оценки·1 отзыв
У всех продавцов:38 оценок·4 отзыва
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6 месяцев назад • Юрий Брыкин • Куплен на Маркете
Достоинства: это прописал доктор
Посмотреть все отзывы на Маркете
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    Ophthalmix Bio Fresh Eyes капли фл., 1%, 10 мл

    Цена 295 ₽ вместо 485
  • Дорзолан соло гл. капли, 20 мг/мл, 5 мл, 1 шт.
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    Дорзолан соло гл. капли, 20 мг/мл, 5 мл, 1 шт.

    Цена 309 ₽
  • Альфаган Р гл.капли фл.-капельница, 0.15%, 5 мл, 1 шт.
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    Альфаган Р гл.капли фл.-капельница, 0.15%, 5 мл, 1 шт.

    Цена 987 ₽
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    Реклама
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  • Окупрес-Е гл. капли, 0.25%, 5 мл
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    Окупрес-Е гл. капли, 0.25%, 5 мл

    Цена 30 ₽
  • Офтаквикс гл. капли фл.-кап., 5 мл
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    Офтаквикс гл. капли фл.-кап., 5 мл

    Цена 254 ₽ вместо 304
  • Тимолол гл. капли, 0.5%, 5 мл, 1 шт.
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    Тимолол гл. капли, 0.5%, 5 мл, 1 шт.

    Цена 74 ₽
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