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Валокордин-доксиламин капли, 25 мг/мл, 20 мл, 1 шт.

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Коротко о товаре

Артикул Маркета
3123243150
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
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Часто расстройства сна обусловлены ухудшением состояния здоровья или психическими расстройствами и могут быть устранены другими мерами или непосредственным лечением основного заболевания. Поэтому не следует проводить лечение хронических нарушений сна (затруднения засыпания и ночных пробуждений) препаратом Валокордин-Доксиламин в течение длительного времени без консультаций с лечащим врачом; в таких случаях рекомендуется обратиться к врачу."},{"name":"Противопоказания","value":"Повышенная чувствительность к доксиламину, какому-либо компоненту препарата, а также к другим антигистаминным препаратам;\u003Cbr\u003E- острый астматический приступ;\u003Cbr\u003E- закрытоугольная глаукома;\u003Cbr\u003E- врожденный синдром удлиненного интервала QT;\u003Cbr\u003E- феохромоцитома;\u003Cbr\u003E- гиперплазия предстательной железы с нарушением оттока мочи;\u003Cbr\u003E- возраст до 18 лет;\u003Cbr\u003E- острые отравления алкоголем и снотворными препаратами, наркотическими анальгетиками, нейролептиками, транквилизаторами, антидепрессантами, препаратами лития;\u003Cbr\u003E- эпилепсия;\u003Cbr\u003E- одновременный прием ингибиторов моноаминоксидазы (МАО);\u003Cbr\u003E- период грудного вскармливания.\u003Cbr\u003EПациентам с бронхиальной астмой или другими респираторными заболеваниями, которые характеризуются повышенной чувствительностью дыхательных путей, не следует применять Валокордин®-Доксиламин, поскольку в нем содержится мятное масло, вдыхание которого может вызвать бронхоспазм.\u003Cbr\u003EС осторожностью:\u003Cbr\u003E- беременность,\u003Cbr\u003E- печеночная недостаточность,\u003Cbr\u003E- алкоголизм,\u003Cbr\u003E- сердечная недостаточность,\u003Cbr\u003E- артериальная гипертензия,\u003Cbr\u003E- бронхоспазм в анамнезе, хроническая одышка,\u003Cbr\u003E- желудочно-пищеводный рефлюкс,\u003Cbr\u003E- пилоростеноз, ахалазия кардии,\u003Cbr\u003E- возраст старше 65 лет (возможность развития головокружений, опасность потери равновесия и падения при ночных пробуждениях, а так же в связи с возможным увеличением Т1/2 доксиламина).\u003Cbr\u003EВалокордин-Доксиламин необходимо с особой осторожностью назначать пациентам с локальным повреждением коры головного мозга и судорожными припадками в анамнезе, поскольку даже небольшие дозы препарата могут спровоцировать тяжелые приступы эпилепсии.\u003Cbr\u003EРекомендуется проводить ЭЭГ (электроэнцефалография).\u003Cbr\u003EПротивосудорожная терапия не должна прерываться во время применения препарата Валокордин-Доксиламин."},{"name":"Состав","value":"Действующее вещество: доксиламина сукцинат – 25 мг\u003Cbr\u003EВспомогательные вещества: этанол 96% – 450 мг, масло мятное – 1.4 мг, вода очищенная – 449.7 мг."},{"name":"Действующее вещество","value":"Доксиламин","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["27144131:28709354"]}}},{"name":"Способ применения и дозы","value":"Если врачом не назначено иначе, то разовая доза Валокордина-Доксиламина для пациентов старше 18 лет составляет 22 капли (соответствует 25 мг доксиламина сукцината).\u003Cbr\u003EПри недостаточной эффективности терапии доза может быть увеличена до максимальной - 44 капли (50 мг).\u003Cbr\u003EНельзя превышать максимальную суточную дозу.\u003Cbr\u003EКапли следует принимать внутрь с 100-150 мл жидкости (воды) за 0.5-1 ч до желаемого времени наступления сна.\u003Cbr\u003EПосле приема препарата Валокордин®-Доксиламин необходимо обеспечить достаточную длительность сна, что позволит избежать нарушения психомоторных реакций утром.\u003Cbr\u003EПри острых нарушениях сна по возможности следует ограничиться однократным применением. Чтобы проверить необходимость продолжения лечения при регулярных нарушениях сна, рекомендуется не позднее чем через 14 дней после начала ежедневного применения перейти к постепенному снижению дозы.\u003Cbr\u003EПрименение у особых групп пациентов\u003Cbr\u003EПациенты с почечной и/или печеночной недостаточностью, а также пациенты старше 65 лет могут быть более восприимчивы к действию доксиламина, в связи с чем, рекомендуется снижение его дозы. Продолжительность приема\u003Cbr\u003EОбычно продолжительность лечения составляет 2-5 дней, максимальная длительность лечения доксиламином - 14 дней. При острых нарушениях сна по возможности следует ограничиться однократным применением."},{"name":"Побочные действия","value":"Частота потенциальных нежелательных реакций классифицирована следующим образом:\u003Cbr\u003Eочень часто (≥1/10), часто (≥1/100 до \u003C1/10), нечасто (≥1/1000 до \u003C1/100), редко (≥1/10 000 до \u003C1/1000), очень редко (до \u003C1/10 000) и частота неизвестна (невозможно оценить на основании имеющихся данных).\u003Cbr\u003EСо стороны крови и лимфатической системы\u003Cbr\u003EВ исключительных случаях при лечении блокаторами Н1-гистамииовых рецепторов сообщалось о развитии лейкопении, тромбоцитопении, гемолитической анемии, очень редко сообщалось о случаях апластической анемии и агранулоцитоза.\u003Cbr\u003EСо стороны эндокринной системы\u003Cbr\u003EУ пациентов с феохромоцитомой применение блокаторов Н1-гистаминовых рецепторов может вызвать повышение выброса катехоламинов.\u003Cbr\u003EПсихические расстройства\u003Cbr\u003EК нежелательным реакциям, зависящим от индивидуальной восприимчивости и принятой дозы относятся: снижение скорости\u003Cbr\u003Eпсихомоторных реакций, снижение концентрации внимания, депрессия. Кроме того, возможно возникновение \"парадоксальных\" реакций: беспокойство, ажитация, тревога, бессонница, ночные кошмары, спутанность сознания, галлюцинации, тремор. \u003Cbr\u003EПосле длительного ежедневного применения резкая отмена терапии может привести к \"рикошетной\" бессоннице.\u003Cbr\u003EЛекарственная зависимость\u003Cbr\u003EПодобно другим снотворным средствам, доксиламин может вызвать физическую и психическую зависимости. Риск зависимости повышается с увеличением дозы и длительности лечения, а также у пациентов с алкогольной, наркотической зависимостью (в том числе в анамнезе). \"Рикошетная\" бессонница.\u003Cbr\u003EДаже после коротких курсов приема доксиламина, его отмена может привести к рецидиву бессонницы. Поэтому прекращать лечение следует, постепенно снижая дозу.\u003Cbr\u003EАнтероградная амнезия\u003Cbr\u003EДаже в терапевтических дозах доксиламин может вызвать антероградную амнезию, особенно в течение первого часа после его приема. Риск возрастает с увеличением дозы, однако может быть снижен благодаря непрерывному сну достаточной продолжительности (7-8 ч).\u003Cbr\u003EСо стороны нервной системы\u003Cbr\u003EГоловокружение, сонливость, головная боль. В редких случаях возможны судороги.\u003Cbr\u003EСо стороны органа зрения\u003Cbr\u003EНарушения аккомодации, повышение внутриглазного давления.\u003Cbr\u003EСо стороны органа слуха и равновесия\u003Cbr\u003EШум в ушах.\u003Cbr\u003EСо стороны сердечно-сосудистой системы\u003Cbr\u003EТахикардия, аритмия, снижение или повышение артериального давления, декомпенсированная сердечная недостаточность. В нескольких случаях обнаруживались изменения на ЭКГ.\u003Cbr\u003EСо стороны органов дыхания, грудной клетки н средостения\u003Cbr\u003EСгущение бронхиального секрета, бронхиальная обструкция, бронхоспазм, которые могут привести к нарушению функции легких. \u003Cbr\u003EСо стороны желудочно-кишечного тракта\u003Cbr\u003EАвтономные нежелательные реакции, такие как: сухость во рту и запор; могут возникнуть тошнота, рвота, диарея, снижение или повышение аппетита, боль в эпигастрии. В очень редких случаях - угрожающая жизни паралитическая кишечная непроходимость.\u003Cbr\u003EСо стороны печени и желчевыводящих путей\u003Cbr\u003EНа фоне антигистаминной терапии сообщалось о нарушениях функции печени (холестатическая желтуха).\u003Cbr\u003EСо стороны кожи и подкожной клетчатки\u003Cbr\u003EКожные аллергические реакции, фотосенсибилизация, нарушение терморегуляции.\u003Cbr\u003EСо стороны костно-мышечной системы и соединительной ткани\u003Cbr\u003EМышечная слабость.\u003Cbr\u003EСо стороны почек и мочевыводящих путей\u003Cbr\u003EНарушение мочеиспускания.\u003Cbr\u003EОбщие расстройства и расстройства в месте введения\u003Cbr\u003EЗаложенность носа, усталость, вялость.\u003Cbr\u003EРазвитие привыкания\u003Cbr\u003EРегулярное применение может привести к снижению эффективности (привыканию).\u003Cbr\u003EПримечания\u003Cbr\u003EТщательный индивидуальный подбор суточной дозы позволяет снизить частоту и тяжесть нежелательных реакций. Риск возникновения нежелательных реакций выше у пожилых пациентов, что может увеличивать у них риск падений."},{"name":"Фармакологическое действие","value":"Блокатор Н1-гистаминовых рецепторов из группы этаноламинов. Оказывает снотворное, седативное, антигистаминное и м-холиноблокирующее действия. Сокращает время засыпания, повышает длительность и качество сна, не изменяя фазы сна.\u003Cbr\u003EДействие начинается в течение 30 мин после приема доксиламина, его продолжительность 3-6 ч."},{"name":"Фармакологическая группа","value":"седативные средства"},{"name":"Форма выпуска","value":"капли для приема внутрь"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"Хранить при температуре до 25°С."},{"name":"Передозировка","value":"Симптомы: дневная сонливость, расширение зрачка (Мидриаз), нарушения аккомодации, сухость во рту, покраснение кожи лица и шеи (гиперемия), повышение температуры тела (гипертермия), синусовая тахикардия, расстройство сознания, галлюцинации, снижение настроения, тревога, нарушение координации движений, дрожь (тремор), непроизвольные движения (Атетоз), судороги (эпилептический синдром), кома.\u003Cbr\u003EНепроизвольные движения иногда являются предвестниками судорог, что может свидетельствовать о тяжелой степени отравления. Даже при отсутствии судорог тяжелые отравления доксиламином могут вызвать развитие рабдомиолиза, который часто сопровождается тяжелой почечной недостаточностью. В таких случаях показана стандартная терапия с постоянным контролем активности креатинфосфокиназы.\u003Cbr\u003EЛечение: при появлении симптомов отравления следует немедленно обратиться к врачу. Симптоматическое лечение (м-холиномиметики и др.), в качестве средства первой помощи показан прием активированного уголя (в количестве 50 г)."},{"name":"Применение при беременности и кормлении грудью","value":"Эксперименты на животных не выявили каких-либо данных о наличии тератогенных свойств у доксиламина, а также снижении фертильности на его фоне. Эпидемиологические исследования лекарственных препаратов, содержащих доксиламина сукцинат, не выявили развития тератогенных эффектов у людей. Тем не менее, Валокордин-Доксиламин может применяться во время беременности только когда предполагаемая польза для матери превышает возможный риск для плода.\u003Cbr\u003EКормление грудью во время лечения препаратом Валокордин®-Доксиламин должно быть прекращено, поскольку действующее вещество проникает в грудное молоко."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Данный лекарственный препарат (даже при его надлежащем употреблении) может оказывать отрицательный эффект на способность активного участия в дорожном движении или управления другими механизмами. Особенно при одновременном употреблении лекарственного препарата и алкоголя. Поэтому следует избегать вождения автомобиля, обслуживания других механизмов и любой деятельности в условиях повышенного риска, по крайней мере, в течение первой фазы лечения. Лечащий врач принимает решение в каждом конкретном случае с учетом индивидуальной быстроты реакции, назначенной дозировки."},{"name":"Особые указания","value":"Валокордин-Доксиламин содержит 55 об. % этанола (до 900 мг на дозу (22 капли), что соответствует 21,87 мл пива или 9,11 мл вина), что может\u003Cbr\u003Eпредставлять опасность для людей с заболеваниями печени, алкоголизмом, эпилепсией, а также для беременных женщин.\u003Cbr\u003EПосле приема препарата следует обеспечить достаточное время для сна (профилактика замедленной психомоторной реакции после пробуждения). Как все снотворные и седативные препараты, доксиламина сукцинат может усугублять течение синдрома ночного апноэ - увеличивать число и продолжительность приступов внезапной остановки дыхания во сне.\u003Cbr\u003EВо время лечения антигистаминными препаратами необходим регулярный контроль функции сердца, так как имеются сообщения об изменениях ЭКГ, в частности изменениях фазы реполяризации. Это особенно важно для пациентов пожилого возраста и больных с сердечной недостаточностью. Особую осторожность необходимо проявлять при лечении пациентов с артериальной гипертензией, поскольку антигистаминные препараты могут повышать АД."},{"name":"Взаимодействие","value":"При одновременном применении с антидепрессантами, барбитуратами, бензодиазепинами, клонидином, опиоидными анальгетиками, нейролептиками, транквилизаторами усиливается угнетающее действие доксиламина на ЦНС.\u003Cbr\u003EПри одновременном применении с атропином и атропиноподобными средствами, имипрамином, противопаркинсоническими средствами с антихолинергическим действием, дизопирамидом, производными фенотиазина повышается риск развития антихолинергических побочных эффектов (сухость во рту, запор, задержка мочеиспускания).\u003Cbr\u003EПри одновременном применении с этанолом усиливается седативное действие доксиламина."},{"name":"Источник","value":"\u003Ca href=\"https://www.vidal.ru\" target=\"_blank\"\u003EСправочник лекарственных препаратов Видаль<\u002Fa\u003E"},{"name":"Регистрационный номер","value":"ЛП-000013"},{"name":"Дата государственной регистрации","value":"16.10.2015"},{"name":"Владелец регистрационного удостоверения","value":"Krewel Meuselbach","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["34324371:35649313","7893318:16127921"]}}},{"name":"Изготовитель","value":"Krewel Meuselbach"},{"name":"Фасовщик","value":"Krewel Meuselbach"},{"name":"Страна бренда","value":"Германия"},{"name":"Страна-производитель","value":"Германия"},{"name":"Название препарата","value":"Валокордин","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["17796364:18007942"]}}},{"name":"Срок годности","value":"60 мес."}]}},"fullSpecsGrouped":{"2604967096386680153":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"нервная система"},{"name":"Назначение","value":"нарушение сна"},{"name":"Показания к применению","value":"Симптоматическое лечение периодически возникающих нарушений сна у пациентов старше 18 лет (затруднение засыпания и ночные пробуждения).\u003Cbr\u003EПримечание\u003Cbr\u003EНе все расстройства сна требуют медикаментозной терапии. Часто расстройства сна обусловлены ухудшением состояния здоровья или психическими расстройствами и могут быть устранены другими мерами или непосредственным лечением основного заболевания. Поэтому не следует проводить лечение хронических нарушений сна (затруднения засыпания и ночных пробуждений) препаратом Валокордин-Доксиламин в течение длительного времени без консультаций с лечащим врачом; в таких случаях рекомендуется обратиться к врачу."},{"name":"Противопоказания","value":"Повышенная чувствительность к доксиламину, какому-либо компоненту препарата, а также к другим антигистаминным препаратам;\u003Cbr\u003E- острый астматический приступ;\u003Cbr\u003E- закрытоугольная глаукома;\u003Cbr\u003E- врожденный синдром удлиненного интервала QT;\u003Cbr\u003E- феохромоцитома;\u003Cbr\u003E- гиперплазия предстательной железы с нарушением оттока мочи;\u003Cbr\u003E- возраст до 18 лет;\u003Cbr\u003E- острые отравления алкоголем и снотворными препаратами, наркотическими анальгетиками, нейролептиками, транквилизаторами, антидепрессантами, препаратами лития;\u003Cbr\u003E- эпилепсия;\u003Cbr\u003E- одновременный прием ингибиторов моноаминоксидазы (МАО);\u003Cbr\u003E- период грудного вскармливания.\u003Cbr\u003EПациентам с бронхиальной астмой или другими респираторными заболеваниями, которые характеризуются повышенной чувствительностью дыхательных путей, не следует применять Валокордин®-Доксиламин, поскольку в нем содержится мятное масло, вдыхание которого может вызвать бронхоспазм.\u003Cbr\u003EС осторожностью:\u003Cbr\u003E- беременность,\u003Cbr\u003E- печеночная недостаточность,\u003Cbr\u003E- алкоголизм,\u003Cbr\u003E- сердечная недостаточность,\u003Cbr\u003E- артериальная гипертензия,\u003Cbr\u003E- бронхоспазм в анамнезе, хроническая одышка,\u003Cbr\u003E- желудочно-пищеводный рефлюкс,\u003Cbr\u003E- пилоростеноз, ахалазия кардии,\u003Cbr\u003E- возраст старше 65 лет (возможность развития головокружений, опасность потери равновесия и падения при ночных пробуждениях, а так же в связи с возможным увеличением Т1/2 доксиламина).\u003Cbr\u003EВалокордин-Доксиламин необходимо с особой осторожностью назначать пациентам с локальным повреждением коры головного мозга и судорожными припадками в анамнезе, поскольку даже небольшие дозы препарата могут спровоцировать тяжелые приступы эпилепсии.\u003Cbr\u003EРекомендуется проводить ЭЭГ (электроэнцефалография).\u003Cbr\u003EПротивосудорожная терапия не должна прерываться во время применения препарата Валокордин-Доксиламин."},{"name":"Состав","value":"Действующее вещество: доксиламина сукцинат – 25 мг\u003Cbr\u003EВспомогательные вещества: этанол 96% – 450 мг, масло мятное – 1.4 мг, вода очищенная – 449.7 мг."},{"name":"Действующее вещество","value":"Доксиламин"},{"name":"Способ применения и дозы","value":"Если врачом не назначено иначе, то разовая доза Валокордина-Доксиламина для пациентов старше 18 лет составляет 22 капли (соответствует 25 мг доксиламина сукцината).\u003Cbr\u003EПри недостаточной эффективности терапии доза может быть увеличена до максимальной - 44 капли (50 мг).\u003Cbr\u003EНельзя превышать максимальную суточную дозу.\u003Cbr\u003EКапли следует принимать внутрь с 100-150 мл жидкости (воды) за 0.5-1 ч до желаемого времени наступления сна.\u003Cbr\u003EПосле приема препарата Валокордин®-Доксиламин необходимо обеспечить достаточную длительность сна, что позволит избежать нарушения психомоторных реакций утром.\u003Cbr\u003EПри острых нарушениях сна по возможности следует ограничиться однократным применением. Чтобы проверить необходимость продолжения лечения при регулярных нарушениях сна, рекомендуется не позднее чем через 14 дней после начала ежедневного применения перейти к постепенному снижению дозы.\u003Cbr\u003EПрименение у особых групп пациентов\u003Cbr\u003EПациенты с почечной и/или печеночной недостаточностью, а также пациенты старше 65 лет могут быть более восприимчивы к действию доксиламина, в связи с чем, рекомендуется снижение его дозы. Продолжительность приема\u003Cbr\u003EОбычно продолжительность лечения составляет 2-5 дней, максимальная длительность лечения доксиламином - 14 дней. При острых нарушениях сна по возможности следует ограничиться однократным применением."},{"name":"Побочные действия","value":"Частота потенциальных нежелательных реакций классифицирована следующим образом:\u003Cbr\u003Eочень часто (≥1/10), часто (≥1/100 до \u003C1/10), нечасто (≥1/1000 до \u003C1/100), редко (≥1/10 000 до \u003C1/1000), очень редко (до \u003C1/10 000) и частота неизвестна (невозможно оценить на основании имеющихся данных).\u003Cbr\u003EСо стороны крови и лимфатической системы\u003Cbr\u003EВ исключительных случаях при лечении блокаторами Н1-гистамииовых рецепторов сообщалось о развитии лейкопении, тромбоцитопении, гемолитической анемии, очень редко сообщалось о случаях апластической анемии и агранулоцитоза.\u003Cbr\u003EСо стороны эндокринной системы\u003Cbr\u003EУ пациентов с феохромоцитомой применение блокаторов Н1-гистаминовых рецепторов может вызвать повышение выброса катехоламинов.\u003Cbr\u003EПсихические расстройства\u003Cbr\u003EК нежелательным реакциям, зависящим от индивидуальной восприимчивости и принятой дозы относятся: снижение скорости\u003Cbr\u003Eпсихомоторных реакций, снижение концентрации внимания, депрессия. Кроме того, возможно возникновение \"парадоксальных\" реакций: беспокойство, ажитация, тревога, бессонница, ночные кошмары, спутанность сознания, галлюцинации, тремор. \u003Cbr\u003EПосле длительного ежедневного применения резкая отмена терапии может привести к \"рикошетной\" бессоннице.\u003Cbr\u003EЛекарственная зависимость\u003Cbr\u003EПодобно другим снотворным средствам, доксиламин может вызвать физическую и психическую зависимости. Риск зависимости повышается с увеличением дозы и длительности лечения, а также у пациентов с алкогольной, наркотической зависимостью (в том числе в анамнезе). \"Рикошетная\" бессонница.\u003Cbr\u003EДаже после коротких курсов приема доксиламина, его отмена может привести к рецидиву бессонницы. Поэтому прекращать лечение следует, постепенно снижая дозу.\u003Cbr\u003EАнтероградная амнезия\u003Cbr\u003EДаже в терапевтических дозах доксиламин может вызвать антероградную амнезию, особенно в течение первого часа после его приема. Риск возрастает с увеличением дозы, однако может быть снижен благодаря непрерывному сну достаточной продолжительности (7-8 ч).\u003Cbr\u003EСо стороны нервной системы\u003Cbr\u003EГоловокружение, сонливость, головная боль. В редких случаях возможны судороги.\u003Cbr\u003EСо стороны органа зрения\u003Cbr\u003EНарушения аккомодации, повышение внутриглазного давления.\u003Cbr\u003EСо стороны органа слуха и равновесия\u003Cbr\u003EШум в ушах.\u003Cbr\u003EСо стороны сердечно-сосудистой системы\u003Cbr\u003EТахикардия, аритмия, снижение или повышение артериального давления, декомпенсированная сердечная недостаточность. В нескольких случаях обнаруживались изменения на ЭКГ.\u003Cbr\u003EСо стороны органов дыхания, грудной клетки н средостения\u003Cbr\u003EСгущение бронхиального секрета, бронхиальная обструкция, бронхоспазм, которые могут привести к нарушению функции легких. \u003Cbr\u003EСо стороны желудочно-кишечного тракта\u003Cbr\u003EАвтономные нежелательные реакции, такие как: сухость во рту и запор; могут возникнуть тошнота, рвота, диарея, снижение или повышение аппетита, боль в эпигастрии. В очень редких случаях - угрожающая жизни паралитическая кишечная непроходимость.\u003Cbr\u003EСо стороны печени и желчевыводящих путей\u003Cbr\u003EНа фоне антигистаминной терапии сообщалось о нарушениях функции печени (холестатическая желтуха).\u003Cbr\u003EСо стороны кожи и подкожной клетчатки\u003Cbr\u003EКожные аллергические реакции, фотосенсибилизация, нарушение терморегуляции.\u003Cbr\u003EСо стороны костно-мышечной системы и соединительной ткани\u003Cbr\u003EМышечная слабость.\u003Cbr\u003EСо стороны почек и мочевыводящих путей\u003Cbr\u003EНарушение мочеиспускания.\u003Cbr\u003EОбщие расстройства и расстройства в месте введения\u003Cbr\u003EЗаложенность носа, усталость, вялость.\u003Cbr\u003EРазвитие привыкания\u003Cbr\u003EРегулярное применение может привести к снижению эффективности (привыканию).\u003Cbr\u003EПримечания\u003Cbr\u003EТщательный индивидуальный подбор суточной дозы позволяет снизить частоту и тяжесть нежелательных реакций. Риск возникновения нежелательных реакций выше у пожилых пациентов, что может увеличивать у них риск падений."},{"name":"Фармакологическое действие","value":"Блокатор Н1-гистаминовых рецепторов из группы этаноламинов. Оказывает снотворное, седативное, антигистаминное и м-холиноблокирующее действия. Сокращает время засыпания, повышает длительность и качество сна, не изменяя фазы сна.\u003Cbr\u003EДействие начинается в течение 30 мин после приема доксиламина, его продолжительность 3-6 ч."},{"name":"Фармакологическая группа","value":"седативные средства"},{"name":"Форма выпуска","value":"капли для приема внутрь"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"Хранить при температуре до 25°С."},{"name":"Передозировка","value":"Симптомы: дневная сонливость, расширение зрачка (Мидриаз), нарушения аккомодации, сухость во рту, покраснение кожи лица и шеи (гиперемия), повышение температуры тела (гипертермия), синусовая тахикардия, расстройство сознания, галлюцинации, снижение настроения, тревога, нарушение координации движений, дрожь (тремор), непроизвольные движения (Атетоз), судороги (эпилептический синдром), кома.\u003Cbr\u003EНепроизвольные движения иногда являются предвестниками судорог, что может свидетельствовать о тяжелой степени отравления. Даже при отсутствии судорог тяжелые отравления доксиламином могут вызвать развитие рабдомиолиза, который часто сопровождается тяжелой почечной недостаточностью. В таких случаях показана стандартная терапия с постоянным контролем активности креатинфосфокиназы.\u003Cbr\u003EЛечение: при появлении симптомов отравления следует немедленно обратиться к врачу. Симптоматическое лечение (м-холиномиметики и др.), в качестве средства первой помощи показан прием активированного уголя (в количестве 50 г)."},{"name":"Применение при беременности и кормлении грудью","value":"Эксперименты на животных не выявили каких-либо данных о наличии тератогенных свойств у доксиламина, а также снижении фертильности на его фоне. Эпидемиологические исследования лекарственных препаратов, содержащих доксиламина сукцинат, не выявили развития тератогенных эффектов у людей. Тем не менее, Валокордин-Доксиламин может применяться во время беременности только когда предполагаемая польза для матери превышает возможный риск для плода.\u003Cbr\u003EКормление грудью во время лечения препаратом Валокордин®-Доксиламин должно быть прекращено, поскольку действующее вещество проникает в грудное молоко."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Данный лекарственный препарат (даже при его надлежащем употреблении) может оказывать отрицательный эффект на способность активного участия в дорожном движении или управления другими механизмами. Особенно при одновременном употреблении лекарственного препарата и алкоголя. Поэтому следует избегать вождения автомобиля, обслуживания других механизмов и любой деятельности в условиях повышенного риска, по крайней мере, в течение первой фазы лечения. Лечащий врач принимает решение в каждом конкретном случае с учетом индивидуальной быстроты реакции, назначенной дозировки."},{"name":"Особые указания","value":"Валокордин-Доксиламин содержит 55 об. % этанола (до 900 мг на дозу (22 капли), что соответствует 21,87 мл пива или 9,11 мл вина), что может\u003Cbr\u003Eпредставлять опасность для людей с заболеваниями печени, алкоголизмом, эпилепсией, а также для беременных женщин.\u003Cbr\u003EПосле приема препарата следует обеспечить достаточное время для сна (профилактика замедленной психомоторной реакции после пробуждения). Как все снотворные и седативные препараты, доксиламина сукцинат может усугублять течение синдрома ночного апноэ - увеличивать число и продолжительность приступов внезапной остановки дыхания во сне.\u003Cbr\u003EВо время лечения антигистаминными препаратами необходим регулярный контроль функции сердца, так как имеются сообщения об изменениях ЭКГ, в частности изменениях фазы реполяризации. Это особенно важно для пациентов пожилого возраста и больных с сердечной недостаточностью. Особую осторожность необходимо проявлять при лечении пациентов с артериальной гипертензией, поскольку антигистаминные препараты могут повышать АД."},{"name":"Взаимодействие","value":"При одновременном применении с антидепрессантами, барбитуратами, бензодиазепинами, клонидином, опиоидными анальгетиками, нейролептиками, транквилизаторами усиливается угнетающее действие доксиламина на ЦНС.\u003Cbr\u003EПри одновременном применении с атропином и атропиноподобными средствами, имипрамином, противопаркинсоническими средствами с антихолинергическим действием, дизопирамидом, производными фенотиазина повышается риск развития антихолинергических побочных эффектов (сухость во рту, запор, задержка мочеиспускания).\u003Cbr\u003EПри одновременном применении с этанолом усиливается седативное действие доксиламина."},{"name":"Источник","value":"\u003Ca href=\"https://www.vidal.ru\" target=\"_blank\"\u003EСправочник лекарственных препаратов Видаль<\u002Fa\u003E"},{"name":"Регистрационный номер","value":"ЛП-000013"},{"name":"Дата государственной регистрации","value":"16.10.2015"},{"name":"Владелец регистрационного удостоверения","value":"Krewel Meuselbach"},{"name":"Изготовитель","value":"Krewel Meuselbach"},{"name":"Фасовщик","value":"Krewel Meuselbach"},{"name":"Страна бренда","value":"Германия"},{"name":"Страна-производитель","value":"Германия"},{"name":"Название препарата","value":"Валокордин"},{"name":"Срок годности","value":"60 мес."}]}],"transitionId":"tr_12131218116492676020"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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  • Гармония сна капс., 0.36 г
    –58 %
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    Гармония сна капс., 0.36 г

    Рейтинг товара: 4.4 из 5
    на основе 60 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 311 ₽ вместо 338
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  • Good Sleep спрей фл., 30 мл, 10 г, 1 шт., мятный, 1 уп.
    –1 %
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    Good Sleep спрей фл., 30 мл, 10 г, 1 шт., мятный, 1 уп.

    Рейтинг товара: 4.6 из 5
    на основе 266 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 1 415 ₽ вместо 1 429
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  • Ново-Сед капс., 10 мл, 10 г, 30 шт., нейтральный, 1 уп.
    –18 %
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    Ново-Сед капс., 10 мл, 10 г, 30 шт., нейтральный, 1 уп.

    Рейтинг товара: 4.7 из 5
    на основе 77 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 333 ₽ вместо 339
    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  • GLS Триптофан капс., 500 мг, 0.25 г, 90 шт.
    –10 %
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    GLS Триптофан капс., 500 мг, 0.25 г, 90 шт.

    Рейтинг товара: 4.8 из 5
    на основе 23 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 540 ₽ вместо 550
    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Триптофан капс., 500 мг, 0.25 г, 90 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  • Баю-бай капли д/вн. приема, 50 мл, 1 шт.
    –1 %
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    Баю-бай капли д/вн. приема, 50 мл, 1 шт.

    Рейтинг товара: 4.9 из 5
    на основе 14 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 381 ₽ вместо 385
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  • Формула сна экспресс таб. д/рассас., 40 шт.
    –1 %
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    Формула сна экспресс таб. д/рассас., 40 шт.

    Рейтинг товара: 3.7 из 5
    на основе 3 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 483 ₽ вместо 488
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  • Валемидин Плюс сироп д/вн. приема, 100 мл, 1 шт.
    –2 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-k8t4vk0hmv/toggleWishlist":{"skuId":"228007356","productId":1404748576,"offerId":"SoysqstHg3B-o7G0wh2wZg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ28aR2v7l+a8zEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIoIbrnQUQvLvcbBjHjvgHIO3ZwQc=","sign":"MBsvhlUtz9Hz2yC1dWK/ZjO8M8+TcSCMKxP9sh38mk4="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-k8t4vk0hmv/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Валемидин Плюс сироп д/вн. приема, 100 мл, 1 шт.

    Рейтинг товара: 4.8 из 5
    на основе 6 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 465 ₽ вместо 475
    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  • Вечернее Биокор др., 60 шт., 1 уп.
    –1 %
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    Вечернее Биокор др., 60 шт., 1 уп.

    Рейтинг товара: 4.6 из 5
    на основе 19 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 119 ₽ вместо 120
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  • Невронорм таб., 30 шт.
    –1 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-hkllepteps9/toggleWishlist":{"skuId":"952622742","productId":1778173206,"offerId":"YS4X6kEYLvrLawgRmfFaOw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ28aR2v7l+a8zEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYIlorzzwYQlr2fxgMYisCQESDt2cEH","sign":"gTcIWuV9jIe7Y4hvv/9padAFSCKpESIkarKQDLNae6w="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-hkllepteps9/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Невронорм таб., 30 шт.

    Рейтинг товара: 5 из 5
    на основе 11 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 277 ₽ вместо 280
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  • Формула сна усиленная фито-мелатонином капс., 30 шт.
    –1 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-sjww3qnr1cs/toggleWishlist":{"skuId":"265134739","productId":1778172926,"offerId":"CoNX7WGTSgC2io1FL4lQ2g","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ28aR2v7l+a8zEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI/ofzzwYQk8W2fhjVu6EGIO3ZwQc=","sign":"LQ5a5hd27zleJjjpc1l85bv8zOfxygRPBAvcapvFHHs="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-sjww3qnr1cs/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Формула сна усиленная фито-мелатонином капс., 30 шт.

    Рейтинг товара: 4 из 5
    на основе 11 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 613 ₽ вместо 619
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Инструкция

Показания к применению

Симптоматическое лечение периодически возникающих нарушений сна у пациентов старше 18 лет (затруднение засыпания и ночные пробуждения).
Примечание
Не все расстройства сна требуют медикаментозной терапии. Часто расстройства сна обусловлены ухудшением состояния здоровья или психическими расстройствами и могут быть устранены другими мерами или непосредственным лечением основного заболевания. Поэтому не следует проводить лечение хронических нарушений сна (затруднения засыпания и ночных пробуждений) препаратом Валокордин-Доксиламин в течение длительного времени без консультаций с лечащим врачом; в таких случаях рекомендуется обратиться к врачу.

Противопоказания

Повышенная чувствительность к доксиламину, какому-либо компоненту препарата, а также к другим антигистаминным препаратам;
- острый астматический приступ;
- закрытоугольная глаукома;
- врожденный синдром удлиненного интервала QT;
- феохромоцитома;
- гиперплазия предстательной железы с нарушением оттока мочи;
- возраст до 18 лет;
- острые отравления алкоголем и снотворными препаратами, наркотическими анальгетиками, нейролептиками, транквилизаторами, антидепрессантами, препаратами лития;
- эпилепсия;
- одновременный прием ингибиторов моноаминоксидазы (МАО);
- период грудного вскармливания.
Пациентам с бронхиальной астмой или другими респираторными заболеваниями, которые характеризуются повышенной чувствительностью дыхательных путей, не следует применять Валокордин®-Доксиламин, поскольку в нем содержится мятное масло, вдыхание которого может вызвать бронхоспазм.
С осторожностью:
- беременность,
- печеночная недостаточность,
- алкоголизм,
- сердечная недостаточность,
- артериальная гипертензия,
- бронхоспазм в анамнезе, хроническая одышка,
- желудочно-пищеводный рефлюкс,
- пилоростеноз, ахалазия кардии,
- возраст старше 65 лет (возможность развития головокружений, опасность потери равновесия и падения при ночных пробуждениях, а так же в связи с возможным увеличением Т1/2 доксиламина).
Валокордин-Доксиламин необходимо с особой осторожностью назначать пациентам с локальным повреждением коры головного мозга и судорожными припадками в анамнезе, поскольку даже небольшие дозы препарата могут спровоцировать тяжелые приступы эпилепсии.
Рекомендуется проводить ЭЭГ (электроэнцефалография).
Противосудорожная терапия не должна прерываться во время применения препарата Валокордин-Доксиламин.

Способ применения и дозы

Если врачом не назначено иначе, то разовая доза Валокордина-Доксиламина для пациентов старше 18 лет составляет 22 капли (соответствует 25 мг доксиламина сукцината).
При недостаточной эффективности терапии доза может быть увеличена до максимальной - 44 капли (50 мг).
Нельзя превышать максимальную суточную дозу.
Капли следует принимать внутрь с 100-150 мл жидкости (воды) за 0.5-1 ч до желаемого времени наступления сна.
После приема препарата Валокордин®-Доксиламин необходимо обеспечить достаточную длительность сна, что позволит избежать нарушения психомоторных реакций утром.
При острых нарушениях сна по возможности следует ограничиться однократным применением. Чтобы проверить необходимость продолжения лечения при регулярных нарушениях сна, рекомендуется не позднее чем через 14 дней после начала ежедневного применения перейти к постепенному снижению дозы.
Применение у особых групп пациентов
Пациенты с почечной и/или печеночной недостаточностью, а также пациенты старше 65 лет могут быть более восприимчивы к действию доксиламина, в связи с чем, рекомендуется снижение его дозы. Продолжительность приема
Обычно продолжительность лечения составляет 2-5 дней, максимальная длительность лечения доксиламином - 14 дней. При острых нарушениях сна по возможности следует ограничиться однократным применением.
Полная инструкция
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Валокордин-доксиламин капли
Валокордин-доксиламин капли, 25 мг/мл, 20 мл, 1 шт.
5.0
(5)
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2 вопроса
Инструкция

383 ₽

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5.0
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У продавца:5 оценок·2 отзыва
У всех продавцов:35 оценок·16 отзывов
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user avatar
9 месяцев назад • АХМАДБЕК А. • Куплен на Маркете
Достоинства: Рекомендую
Недостатки: Нет
Комментарий: Понимать за час полтора до сна.
user avatar
2 месяца назад • Ирина О. • Куплен на Маркете
Достоинства: Хорошо помогает
Недостатки: По рецепту
Посмотреть все отзывы на Маркете
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  • Гармония сна капс., 0.36 г
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    Гармония сна капс., 0.36 г

    Цена 311 ₽ вместо 742
  • GLS Триптофан капс., 500 мг, 0.25 г, 90 шт.
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    GLS Триптофан капс., 500 мг, 0.25 г, 90 шт.

    Цена 540 ₽ вместо 600
  • Баю-бай капли д/вн. приема, 50 мл, 1 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778172718_4/content/content/gallery":{"title":"Баю-бай капли д/вн. приема, 50 мл, 1 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/5320546/img_id4151063834720017339.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5320546/img_id4151063834720017339.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5320546/img_id4151063834720017339.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5320546/img_id4151063834720017339.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5320546/img_id4151063834720017339.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5320546/img_id4151063834720017339.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/1884605/img_id3331443076729689152.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/1884605/img_id3331443076729689152.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/1884605/img_id3331443076729689152.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/1884605/img_id3331443076729689152.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/1884605/img_id3331443076729689152.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/1884605/img_id3331443076729689152.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/3907093/img_id831959120345563461.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/3907093/img_id831959120345563461.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/3907093/img_id831959120345563461.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/3907093/img_id831959120345563461.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/3907093/img_id831959120345563461.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/3907093/img_id831959120345563461.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4420830/img_id9219961158002034064.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4420830/img_id9219961158002034064.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4420830/img_id9219961158002034064.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4420830/img_id9219961158002034064.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4420830/img_id9219961158002034064.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4420830/img_id9219961158002034064.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ28aR2v7l+a8zEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIVCK6G888GEN2h3GwYz76HESDt2cEH","sign":"Zwv6oXtQKw1ap3zhWKePb4HFLI461pBXncuRXoWl3X8="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778172718_4/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
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    Баю-бай капли д/вн. приема, 50 мл, 1 шт.

    Цена 381 ₽ вместо 385
  • Формула сна экспресс таб. д/рассас., 40 шт.
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    Формула сна экспресс таб. д/рассас., 40 шт.

    Цена 483 ₽ вместо 488
  • Вечернее Биокор др., 60 шт., 1 уп.
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    Вечернее Биокор др., 60 шт., 1 уп.

    Цена 119 ₽ вместо 120
  • Валемидин Плюс сироп д/вн. приема, 100 мл, 1 шт.
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    Валемидин Плюс сироп д/вн. приема, 100 мл, 1 шт.

    Цена 449 ₽ вместо 454
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    Реклама
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  • Невронорм таб., 30 шт.
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    Невронорм таб., 30 шт.

    Цена 277 ₽ вместо 280
  • Ново-Сед капс., 10 мл, 10 г, 30 шт., нейтральный, 1 уп.
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778172996_10/content/content/toggleWishlist":{"skuId":"555927079","productId":1778172996,"offerId":"E-Szav46-Qp8U5qxV3LAag","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ28aR2v7l+a8zEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCMSI888GEKeMi4kCGLbUzwYg7dnBBw==","sign":"b/BUckw2LwFDZP0F9GbSuX6dssPkW+1110vxEGgeD0Y="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778172996_10/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Ново-Сед капс., 10 мл, 10 г, 30 шт., нейтральный, 1 уп.

    Цена 333 ₽ вместо 407
  • Формула сна усиленная фито-мелатонином капс., 30 шт.
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    Формула сна усиленная фито-мелатонином капс., 30 шт.

    Цена 613 ₽ вместо 619
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