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Описание

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Велаксин таб., 75 мг, 28 шт.

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5.0
(7)
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Коротко о товаре

Артикул Маркета
2227843697
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
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Если после нескольких недель лечения не наблюдается значительного улучшения, суточную дозу можно повысить до 150 мг (2 х 75 мг в день).\u003Cbr\u003EЕсли, по мнению врача, необходима более высокая доза (тяжелое депрессивное расстройство или другие состояния, требующие стационарного лечения), можно сразу назначить 150 мг в два приема (2 х 75 мг в день). После этого суточную дозу можно увеличивать на 75 мг каждые 2-3 дня до достижения желаемого терапевтического эффекта.\u003Cbr\u003EМаксимальная суточная доза препарата Велаксин составляет 375 мг. После достижения необходимого терапевтического эффекта суточная доза может быть постепенно снижена до минимального эффективного уровня.\u003Cbr\u003EПоддерживающая терапия и профилактика рецидивов:\u003Cbr\u003EПоддерживающее лечение может продолжаться 6 месяцев и более. Назначаются минимальные эффективные дозы, применявшиеся при лечении депрессивного эпизода.\u003Cbr\u003EПочечная недостаточность: при легкой почечной недостаточности (скорость клубочковой фильтрации (СКФ) более 30 мл/мин) коррекция режима дозирования не требуется. При умеренной почечной недостаточности (СКФ 10-30 мл/мин) дозу следует снизить на 25-50%. В связи с удлинением периода полувыведения венлафаксина и его активного метаболита (ОДВ), таким пациентам следует принимать всю дозу один раз в день. Не рекомендуется применять венлафаксин при тяжелой почечной недостаточности (СКФ менее 10 мл/мин), поскольку надежные данные о такой терапии отсутствуют. Пациенты на гемодиализе могут получать 50% обычной суточной дозы венлафаксина после завершения гемодиализа.\u003Cbr\u003EПеченочная недостаточность: при легкой печеночной недостаточности (протромбиновое время (ПВ) менее 14 сек) коррекция режима дозирования не требуется. При умеренной печеночной недостаточности (ПВ от 14 до 18 сек) дозу следует снизить на 50%. Не рекомендуется применять венлафаксин при тяжелой печеночной недостаточности, поскольку надежные данные о такой терапии отсутствуют.\u003Cbr\u003EПожилые пациенты: сам по себе пожилой возраст пациента не требует изменения дозы, однако (как и при назначении других лекарственных препаратов) при лечении пожилых пациентов требуется осторожность, например, в связи с возможностью нарушения функции почек. Следует применять наименьшую эффективную дозу. При повышении дозы пациент должен находиться под тщательным медицинским наблюдением.\u003Cbr\u003EПрекращение приема препарата Велаксин\u003Cbr\u003EПо окончании приема препарата Велаксин рекомендуется постепенно снижать дозировку препарата, по крайней мере в течение недели, и наблюдать за состоянием пациента для того, чтобы свести к минимуму риск, связанный с отменой препарата (см. ниже).\u003Cbr\u003EПериод, требуемый для полного прекращения приема препарата, зависит от его дозировки, длительности курса лечения и индивидуальных особенностей пациента."},{"name":"Побочные действия","value":"Большинство перечисленных ниже побочных эффектов зависят от дозы. При длительном лечении тяжесть и частота большинства этих эффектов снижается, причем не возникает необходимость отмены терапии.\u003Cbr\u003EВ порядке снижения частоты: частые ≥ 1%, нечастые ≥ 0,1% - \u003C 1%, редкие ≥ 0,01% - \u003C 0,1%, очень редкие \u003C 0,01%.\u003Cbr\u003EОбщие симптомы: слабость, повышенная утомляемость.\u003Cbr\u003EСо стороны желудочно-кишечного тракта: снижение аппетита, запор, тошнота, рвота, сухость во рту, редко гепатит.\u003Cbr\u003EСо стороны обмена веществ: повышение уровня холестерина сыворотки крови, снижение веса тела; нечастые: изменение лабораторных проб функции печени, гипонатриемия, синдром недостаточной секреции антидиуретического гормона.\u003Cbr\u003EСо стороны сердечно-сосудистой системы: артериальная гипертензия, гиперемия кожных покровов; нечастые: постуральная гипотензия, тахикардия.\u003Cbr\u003EСо стороны нервной системы: необычные сновидения, головокружение, бессонница, повышенная возбудимость, парестезии, ступор, повышение мышечного тонуса, тремор, зевота; нечастые: апатия, галлюцинации, спазмы мышц, серотониновый синдром; редкие: эпилептические припадки, маниакальные реакции, а также симптомы, напоминающие злокачественный нейролептический синдром (ЗНС).\u003Cbr\u003EСо стороны мочеполовой системы: нарушения эякуляции, эрекции, аноргазмия, дизурические расстройства (в основном - затруднения в начале мочеиспускания); нечастые: снижение либидо, меноррагия, задержка мочи.\u003Cbr\u003EСо стороны органов чувств: нарушения аккомодации, мидриаз, нарушение зрения; нечастые: нарушение вкусовых ощущений.\u003Cbr\u003EСо стороны кожных покровов: потливость; нечастые: реакции светочувствительности; редкие: многоформная эритема, синдром Стивенса-Джонсона.\u003Cbr\u003EСо стороны системы кроветворения: нечастые: кровоизлияния в кожу (экхимозы) и слизистые оболочки, тромбоцитопения; редкие: удлинение времени кровотечения.\u003Cbr\u003EРеакции гиперчувствительности: нечастые: кожная сыпь; очень редкие: анафилактические реакции.\u003Cbr\u003EПосле резкой отмены венлафаксина или снижения его дозы могут наблюдаться: утомляемость, сонливость, головная боль, тошнота, рвота, анорексия, сухость во рту, головокружение, понос, бессонница, тревога, повышенная раздражительность, дезориентация, гипомания, парестезии, потливость. Эти симптомы обычно слабо выражены и проходят без лечения. Из-за вероятности возникновения этих симптомов очень важно постепенно снижать дозу препарата."},{"name":"Фармакологическое действие","value":"Антидепрессант. По химической структуре венлафаксин нельзя отнести ни к одному известному классу антидепрессантов (трициклические, тетрациклические или другие). Он является рацематом двух активных энантиомеров.\u003Cbr\u003EМеханизм антидепрессивного действия препарата связан с его способностью потенциировать передачу нервного импульса в ЦНС. Венлафаксин и его основной метаболит О-десметилвенлафаксин (ОДВ) являются мощными ингибиторами обратного захвата серотонина и норадреналина и слабыми ингибиторами обратного захвата допамина. Кроме того, венлафаксин и ОДВ снижают бета-адренергическую активность как после однократного введения, так и при постоянном приеме. Венлафаксин и ОДВ одинаково эффективно влияют на обратный захват нейротрансмиттеров.\u003Cbr\u003EВенлафаксин не обладает сродством к м- и н-холинорецепторам, гистаминовым H1-рецепторам и α1-адренорецепторам головного мозга. Венлафаксин не подавляет активность МАО. Не обладает сродством к опиоидным, бензодиазепиновым, фенциклидиновым или NMDA-рецепторам."},{"name":"Фармакологическая группа","value":"антидепрессанты"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Условия хранения","value":"Хранить при температуре не выше 30 °С.\u003Cbr\u003EХранить препарат в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы: изменения ЭКГ (удлинение интервала QT, блокада ножки пучка Гиса, расширение комплекса QRS), синусовая или желудочковая тахикардия, брадикардия, гипотензия, судорожные состояния, изменение сознания (снижение уровня бодрствования). При передозировке венлафаксина при одновременном приеме с алкоголем и/или другими психотропными препаратами, сообщалось о смертельном исходе.\u003Cbr\u003EЛечение: симптоматическое. Специфические антидоты неизвестны. Рекомендуется непрерывный контроль жизненно важных функций (дыхания и кровообращения). Назначение активированного угля для снижения всасывания препарата. Не рекомендуется вызывать рвоту в связи с опасностью аспирации. Венлафаксин и ОДВ не выводятся при диализе."},{"name":"Применение при беременности и кормлении грудью","value":"Безопасность применения венлафаксина при беременности не доказана, поэтому применение во время беременности (или предполагаемой беременности) возможно в только в том случае, если потенциальная польза для матери превосходит возможный риск для плода. Женщины детородного возраста должны быть предупреждены об этом до начала лечения и должны немедленно обратиться к врачу в случае наступления беременности или планирования беременности в период лечения препаратом.\u003Cbr\u003EВенлафаксин и его метаболит (ОДВ) выделяются в грудное молоко. Безопасность этих веществ для новорожденных детей не доказана, поэтому прием венлафаксина во время грудного вскармливания не рекомендуется. При необходимости приема препарата в период лактации следует решить вопрос о прекращении грудного вскармливания.\u003Cbr\u003EЕсли лечение матери было завершено незадолго до родов, у новорожденного могут возникнуть симптомы отмены препарата."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Несмотря на то, что венлафаксин не влияет на психомоторные и когнитивные функции, следует учитывать, что любая лекарственная терапия психоактивными препаратами может снизить способность вынесения суждений, мышления или выполнения двигательных функций. Об этом следует предупредить пациента перед началом лечения. При возникновении такого рода нарушений степень и длительность ограничений должны быть установлены врачом."},{"name":"Особые указания","value":"С осторожностью:\u003Cbr\u003EНедавно перенесенный инфаркт миокарда, нестабильная стенокардия, артериальная гипертензия, тахикардия, судорожный синдром в анамнезе, повышение внутриглазного давления, закрытоугольная глаукома, маниакальные состояния в анамнезе, предрасположенность к кровотечениям со стороны кожных покровов и слизистых оболочек, исходно сниженная масса тела.\u003Cbr\u003EОтмена препарата Велаксин: Как и при лечении другими антидепрессантами, резкое прекращение терапии венлафаксином - особенно после высоких доз препарата - может вызвать симптомы отмены, в связи с чем рекомендуется перед отменой препарата постепенно снизить его дозу. Длительность периода, необходимого для снижения дозы, зависит от величины дозы, продолжительности терапии, а также индивидуальной чувствительности пациента.\u003Cbr\u003EПри назначении таблеток Велаксин больным с непереносимостью лактозы следует учитывать содержание лактозы (56,62 мг в каждой таблетке 25 мг; 84,93 мг в каждой таблетке 37,5 мг; 113,24 мг в каждой таблетке 50 мг, 169,86 мг в каждой таблетке 75 мг).\u003Cbr\u003EУ больных с депрессивными расстройствами перед началом любой лекарственной терапии следует учитывать вероятность суицидальных попыток. Поэтому для снижения риска передозировки начальная доза препарата должна быть по возможности низкой, а пациент должен находиться под тщательным медицинским наблюдением.\u003Cbr\u003EУ пациентов с аффективными расстройствами при лечении антидепрессантами, в том числе венлафаксином, могут возникать гипоманиакальные или маниакальные состояния. Как и другие антидепрессанты, венлафаксин должен назначаться с осторожностью больным с манией в анамнезе. Такие пациенты нуждаются в медицинском наблюдении.\u003Cbr\u003EКак и другие антидепрессанты, венлафаксин должен назначаться с осторожностью больным с эпилептическими припадками в анамнезе. Лечение венлафаксином должно быть прервано при возникновении эпилептических припадков.\u003Cbr\u003EПациентов следует предупредить о необходимости немедленно обратиться к врачу при возникновении сыпи, уртикарных элементов или других аллергических реакций.\u003Cbr\u003EУ некоторых больных во время приема венлафаксина отмечено дозозависимое повышение артериального давления, в связи с чем рекомендуется регулярный контроль артериального давления, особенно в период уточнения или повышения дозировки.\u003Cbr\u003EМожет произойти повышение частоты сердечного ритма, особенно во время приема высоких доз. Рекомендуется осторожность при тахиаритмии.\u003Cbr\u003EПациенты, особенно пожилые, должны быть предупреждены о возможности возникновения головокружения и нарушения чувства равновесия.\u003Cbr\u003EКак и другие ингибиторы обратного захвата серотонина, венлафаксин может повысить риск кровоизлияний в кожу и слизистые оболочки. При лечении больных, предрасположенных к таким состояниям, необходима осторожность.\u003Cbr\u003EВо время приема венлафаксина, особенно в условиях дегидратации или снижения объема крови (в том числе у пожилых пациентов и больных, принимающих диуретики), может наблюдаться гипонатриемия и/или синдром недостаточной секреции антидиуретического гормона.\u003Cbr\u003EВо время приема препарата может наблюдаться мидриаз, в связи с чем рекомендуется контроль внутриглазного давления у больных, склонных к его повышению или страдающих закрытоугольной глаукомой.\u003Cbr\u003EВенлафаксин не исследован у пациентов, недавно перенесших инфаркт миокарда и страдающих декомпенсированной сердечной недостаточностью. Таким больным препарат следует назначать с осторожностью.\u003Cbr\u003EПроведенные до настоящего времени клинические испытания не выявили толерантности к венлафаксину или зависимости от него. Несмотря на это, как и при лечении другими препаратами, действующими на центральную нервную систему, врач должен установить тщательное наблюдение за пациентами для выявления признаков злоупотребления препаратом. Тщательный контроль и наблюдение необходимы для пациентов, имеющих в анамнезе такие симптомы.\u003Cbr\u003EЖенщины детородного возраста должны применять соответствующие методы контрацепции во время приема венлафаксина.\u003Cbr\u003EНесмотря на то, что венлафаксин не влияет на психомоторные и когнитивные функции, следует учитывать, что любая лекарственная терапия психоактивными препаратами может снизить способность вынесения суждений, мышления или выполнения двигательных функций. Об этом следует предупредить пациента перед началом лечения. При возникновении таких эффектов степень и длительность ограничений должны быть установлены врачом. Также не рекомендован прием алкоголя."},{"name":"Взаимодействие","value":"Одновременное применение ингибиторов моноаминоксидазы (МАО) и венлафаксина противопоказано. Прием препарата Велаксин можно начинать не менее чем через 14 дней после окончания терапии ингибиторами МАО. Если применялся обратимый ингибитор МАО (моклобемид), этот интервал может быть короче (24 часа). Терапию ингибиторами МАО можно начинать не менее чем через 7 дней после отмены препарата Велаксин.\u003Cbr\u003EВенлафаксин не влияет на фармакокинетику лития.\u003Cbr\u003EПри одновременном применении с имипрамином фармакокинетика венлафаксина и его метаболита О-десметилвенлафаксина (ОДВ) не изменяется.\u003Cbr\u003EГалоперидол: эффект последнего может усиливаться из-за повышения уровня препарата в крови при совместном применении.\u003Cbr\u003EПри одновременном применении с диазепамом фармакокинетика препаратов и их основных метаболитов, существенно не изменяются. Также не обнаружено влияния на психомоторные и психометрические эффекты диазепама.\u003Cbr\u003EПри одновременном применении с клозапином может наблюдаться повышение его уровня в плазме крови и развитие побочных эффектов (например, эпилептических припадков).\u003Cbr\u003EПри одновременном применении с рисперидоном (несмотря на увеличение AUC рисперидона) фармакокинетика суммы активных компонентов (рисперидона и его активного метаболита) существенно не изменялась.\u003Cbr\u003EУсиливает влияние алкоголя на психомоторные реакции.\u003Cbr\u003EНа фоне приема венлафаксина следует соблюдать особую осторожность при электросудорожной терапии, так как опыт применения венлафаксина в этих условиях отсутствует.\u003Cbr\u003EЛекарственные препараты, метаболизируемые изоферментами цитохрома Р 450:\u003Cbr\u003EФермент CYP2D6 системы цитохрома Р 450 преобразует венлафаксин в активный метаболит О-десметилвенлафаксин (ОДВ). В отличие от многих других антидепрессантов, дозу венлафаксина можно не снижать при одновременном введении с препаратами, подавляющими активность CYP2D6, или у пациентов с генетически обусловленным снижением активности CYP2D6, поскольку суммарная концентрация активного вещества и метаболита (венлафаксина и ОДВ) при этом не изменится.\u003Cbr\u003EОсновной путь выведения венлафаксина включает метаболизм с участием CYP2D6 и CYP3A4; поэтому следует соблюдать особую осторожность при назначении венлафаксина в сочетании с лекарственными препаратами, угнетающими оба эти фермента. Такие лекарственные взаимодействия еще не исследованы.\u003Cbr\u003EВенлафаксин - относительно слабый ингибитор CYP2D6 и не подавляет активность изоферментов CYP1А2, CYP2C9 и CYP3A4; поэтому не следует ожидать его взаимодействия с другими препаратами, в метаболизме которых участвуют эти печеночные ферменты.\u003Cbr\u003EЦиметидин подавляет метаболизм \"первого прохождения\" венлафаксина и не оказывает влияние на фармакокинетику О-десметилвенлафаксина. У большинства пациентов ожидается лишь незначительное повышение общей фармакологической активности венлафаксина и О-десметилвенлафаксина (более выражено у пожилых пациентов и при нарушении функции печени).\u003Cbr\u003EКлинически значимые взаимодействия венлафаксина с антигипертензивными (в том числе бета-блокаторами, ингибиторами АПФ и диуретиками) и противодиабетическими препаратами не обнаружены\u003Cbr\u003EЛекарственные препараты, связанные с белками плазмы крови: связывание с белками плазмы составляет 27% для венлафаксина и 30% для ОДВ. Поэтому не влияет на концентрацию лекарственных средств в плазме крови, обладающих высокой степенью связывания с белками.\u003Cbr\u003EПри одновременном приеме с варфарином может усиливаться антикоагулянтный эффект последнего.\u003Cbr\u003EПри одновременном приеме с индинавиром изменяется фармакокинетика индинавира (с 28%-ным уменьшением площади под кривой AUC и 36%-ным снижением максимальной концентрации Сmax), а фармакокинетика венлафаксина и ОДВ не изменяется. Однако клиническое значение этого эффекта неизвестно."},{"name":"Регистрационный номер","value":"ЛC-000318"},{"name":"Дата государственной регистрации","value":"14.08.2019"},{"name":"Владелец регистрационного удостоверения","value":"Egis Pharmaceuticals","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["34324371:35649313","7893318:16002706"]}}},{"name":"Изготовитель","value":"Egis"},{"name":"Фасовщик","value":"Egis"},{"name":"Страна бренда","value":"Венгрия"},{"name":"Страна-производитель","value":"Венгрия"},{"name":"Название препарата","value":"Велаксин","transition":{"type":"catalog","params":{"categorySlug":"sredstva-dlia-nervnoi-sistemy","categoryId":"15756525","navnodeId":"72478","glfilters":["17796364:18020938"]}}},{"name":"Срок годности","value":"60 мес."}]}},"fullSpecsGrouped":{"13503813210368046301":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Рецептурный препарат","value":"да"},{"name":"Органы и системы","value":"нервная система"},{"name":"Назначение","value":"депрессия"},{"name":"Показания к применению","value":"Депрессии различной этиологии, лечение и профилактика."},{"name":"Противопоказания","value":"Гиперчувствительность.\u003Cbr\u003EОдновременный прием ингибиторов МАО (см. также раздел \"Взаимодействие\").\u003Cbr\u003EТяжелые нарушения функции почек и/или печени (скорость клубочковой фильтрации менее (СКФ) 10 мл/мин).\u003Cbr\u003EВозраст до 18 лет (безопасность и эффективность для этой возрастной группы не доказаны).\u003Cbr\u003EУстановленная или подозреваемая беременность.\u003Cbr\u003EПериод лактации."},{"name":"Состав","value":"На 1 таблетку:\u003Cbr\u003Eдействующее вещество: венлафаксина гидрохлорид 28,28 мг/42,42 мг/56,56 мг/84,84 мг, что соответствует венлафаксина 25,00 мг/37,50 мг/50,0 мг/75,00 мг;\u003Cbr\u003Eвспомогательные вещества: лактозы моногидрат 56,62 мг/84,93 мг/113,24 мг/169,86 мг, целлюлоза микрокристаллическая 24,0 мг/36,00 мг/48,00мг/72,00 мг, карбоксиметилкрахмал натрия (тип А) 8,40 мг/12,60 мг/16,80 мг/25,20 мг, кремния диоксид коллоидный безводный 0,90 мг/ 1,35 мг/1,80 мг/2,70 мг, магния стеарат 1,80 мг/2,70 мг/3,60 мг/5,40 мг, соответственно."},{"name":"Действующее вещество","value":"Венлафаксин"},{"name":"Способ применения и дозы","value":"Таблетки Велаксина рекомендуется принимать во время еды.\u003Cbr\u003EРекомендуемая начальная доза составляет 75 мг в два приема (по 37,5 мг) ежедневно. Если после нескольких недель лечения не наблюдается значительного улучшения, суточную дозу можно повысить до 150 мг (2 х 75 мг в день).\u003Cbr\u003EЕсли, по мнению врача, необходима более высокая доза (тяжелое депрессивное расстройство или другие состояния, требующие стационарного лечения), можно сразу назначить 150 мг в два приема (2 х 75 мг в день). После этого суточную дозу можно увеличивать на 75 мг каждые 2-3 дня до достижения желаемого терапевтического эффекта.\u003Cbr\u003EМаксимальная суточная доза препарата Велаксин составляет 375 мг. После достижения необходимого терапевтического эффекта суточная доза может быть постепенно снижена до минимального эффективного уровня.\u003Cbr\u003EПоддерживающая терапия и профилактика рецидивов:\u003Cbr\u003EПоддерживающее лечение может продолжаться 6 месяцев и более. Назначаются минимальные эффективные дозы, применявшиеся при лечении депрессивного эпизода.\u003Cbr\u003EПочечная недостаточность: при легкой почечной недостаточности (скорость клубочковой фильтрации (СКФ) более 30 мл/мин) коррекция режима дозирования не требуется. При умеренной почечной недостаточности (СКФ 10-30 мл/мин) дозу следует снизить на 25-50%. В связи с удлинением периода полувыведения венлафаксина и его активного метаболита (ОДВ), таким пациентам следует принимать всю дозу один раз в день. Не рекомендуется применять венлафаксин при тяжелой почечной недостаточности (СКФ менее 10 мл/мин), поскольку надежные данные о такой терапии отсутствуют. Пациенты на гемодиализе могут получать 50% обычной суточной дозы венлафаксина после завершения гемодиализа.\u003Cbr\u003EПеченочная недостаточность: при легкой печеночной недостаточности (протромбиновое время (ПВ) менее 14 сек) коррекция режима дозирования не требуется. При умеренной печеночной недостаточности (ПВ от 14 до 18 сек) дозу следует снизить на 50%. Не рекомендуется применять венлафаксин при тяжелой печеночной недостаточности, поскольку надежные данные о такой терапии отсутствуют.\u003Cbr\u003EПожилые пациенты: сам по себе пожилой возраст пациента не требует изменения дозы, однако (как и при назначении других лекарственных препаратов) при лечении пожилых пациентов требуется осторожность, например, в связи с возможностью нарушения функции почек. Следует применять наименьшую эффективную дозу. При повышении дозы пациент должен находиться под тщательным медицинским наблюдением.\u003Cbr\u003EПрекращение приема препарата Велаксин\u003Cbr\u003EПо окончании приема препарата Велаксин рекомендуется постепенно снижать дозировку препарата, по крайней мере в течение недели, и наблюдать за состоянием пациента для того, чтобы свести к минимуму риск, связанный с отменой препарата (см. ниже).\u003Cbr\u003EПериод, требуемый для полного прекращения приема препарата, зависит от его дозировки, длительности курса лечения и индивидуальных особенностей пациента."},{"name":"Побочные действия","value":"Большинство перечисленных ниже побочных эффектов зависят от дозы. При длительном лечении тяжесть и частота большинства этих эффектов снижается, причем не возникает необходимость отмены терапии.\u003Cbr\u003EВ порядке снижения частоты: частые ≥ 1%, нечастые ≥ 0,1% - \u003C 1%, редкие ≥ 0,01% - \u003C 0,1%, очень редкие \u003C 0,01%.\u003Cbr\u003EОбщие симптомы: слабость, повышенная утомляемость.\u003Cbr\u003EСо стороны желудочно-кишечного тракта: снижение аппетита, запор, тошнота, рвота, сухость во рту, редко гепатит.\u003Cbr\u003EСо стороны обмена веществ: повышение уровня холестерина сыворотки крови, снижение веса тела; нечастые: изменение лабораторных проб функции печени, гипонатриемия, синдром недостаточной секреции антидиуретического гормона.\u003Cbr\u003EСо стороны сердечно-сосудистой системы: артериальная гипертензия, гиперемия кожных покровов; нечастые: постуральная гипотензия, тахикардия.\u003Cbr\u003EСо стороны нервной системы: необычные сновидения, головокружение, бессонница, повышенная возбудимость, парестезии, ступор, повышение мышечного тонуса, тремор, зевота; нечастые: апатия, галлюцинации, спазмы мышц, серотониновый синдром; редкие: эпилептические припадки, маниакальные реакции, а также симптомы, напоминающие злокачественный нейролептический синдром (ЗНС).\u003Cbr\u003EСо стороны мочеполовой системы: нарушения эякуляции, эрекции, аноргазмия, дизурические расстройства (в основном - затруднения в начале мочеиспускания); нечастые: снижение либидо, меноррагия, задержка мочи.\u003Cbr\u003EСо стороны органов чувств: нарушения аккомодации, мидриаз, нарушение зрения; нечастые: нарушение вкусовых ощущений.\u003Cbr\u003EСо стороны кожных покровов: потливость; нечастые: реакции светочувствительности; редкие: многоформная эритема, синдром Стивенса-Джонсона.\u003Cbr\u003EСо стороны системы кроветворения: нечастые: кровоизлияния в кожу (экхимозы) и слизистые оболочки, тромбоцитопения; редкие: удлинение времени кровотечения.\u003Cbr\u003EРеакции гиперчувствительности: нечастые: кожная сыпь; очень редкие: анафилактические реакции.\u003Cbr\u003EПосле резкой отмены венлафаксина или снижения его дозы могут наблюдаться: утомляемость, сонливость, головная боль, тошнота, рвота, анорексия, сухость во рту, головокружение, понос, бессонница, тревога, повышенная раздражительность, дезориентация, гипомания, парестезии, потливость. Эти симптомы обычно слабо выражены и проходят без лечения. Из-за вероятности возникновения этих симптомов очень важно постепенно снижать дозу препарата."},{"name":"Фармакологическое действие","value":"Антидепрессант. По химической структуре венлафаксин нельзя отнести ни к одному известному классу антидепрессантов (трициклические, тетрациклические или другие). Он является рацематом двух активных энантиомеров.\u003Cbr\u003EМеханизм антидепрессивного действия препарата связан с его способностью потенциировать передачу нервного импульса в ЦНС. Венлафаксин и его основной метаболит О-десметилвенлафаксин (ОДВ) являются мощными ингибиторами обратного захвата серотонина и норадреналина и слабыми ингибиторами обратного захвата допамина. Кроме того, венлафаксин и ОДВ снижают бета-адренергическую активность как после однократного введения, так и при постоянном приеме. Венлафаксин и ОДВ одинаково эффективно влияют на обратный захват нейротрансмиттеров.\u003Cbr\u003EВенлафаксин не обладает сродством к м- и н-холинорецепторам, гистаминовым H1-рецепторам и α1-адренорецепторам головного мозга. Венлафаксин не подавляет активность МАО. Не обладает сродством к опиоидным, бензодиазепиновым, фенциклидиновым или NMDA-рецепторам."},{"name":"Фармакологическая группа","value":"антидепрессанты"},{"name":"Форма выпуска","value":"таблетки"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"Хранить при температуре не выше 30 °С.\u003Cbr\u003EХранить препарат в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы: изменения ЭКГ (удлинение интервала QT, блокада ножки пучка Гиса, расширение комплекса QRS), синусовая или желудочковая тахикардия, брадикардия, гипотензия, судорожные состояния, изменение сознания (снижение уровня бодрствования). При передозировке венлафаксина при одновременном приеме с алкоголем и/или другими психотропными препаратами, сообщалось о смертельном исходе.\u003Cbr\u003EЛечение: симптоматическое. Специфические антидоты неизвестны. Рекомендуется непрерывный контроль жизненно важных функций (дыхания и кровообращения). Назначение активированного угля для снижения всасывания препарата. Не рекомендуется вызывать рвоту в связи с опасностью аспирации. Венлафаксин и ОДВ не выводятся при диализе."},{"name":"Применение при беременности и кормлении грудью","value":"Безопасность применения венлафаксина при беременности не доказана, поэтому применение во время беременности (или предполагаемой беременности) возможно в только в том случае, если потенциальная польза для матери превосходит возможный риск для плода. Женщины детородного возраста должны быть предупреждены об этом до начала лечения и должны немедленно обратиться к врачу в случае наступления беременности или планирования беременности в период лечения препаратом.\u003Cbr\u003EВенлафаксин и его метаболит (ОДВ) выделяются в грудное молоко. Безопасность этих веществ для новорожденных детей не доказана, поэтому прием венлафаксина во время грудного вскармливания не рекомендуется. При необходимости приема препарата в период лактации следует решить вопрос о прекращении грудного вскармливания.\u003Cbr\u003EЕсли лечение матери было завершено незадолго до родов, у новорожденного могут возникнуть симптомы отмены препарата."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"Несмотря на то, что венлафаксин не влияет на психомоторные и когнитивные функции, следует учитывать, что любая лекарственная терапия психоактивными препаратами может снизить способность вынесения суждений, мышления или выполнения двигательных функций. Об этом следует предупредить пациента перед началом лечения. При возникновении такого рода нарушений степень и длительность ограничений должны быть установлены врачом."},{"name":"Особые указания","value":"С осторожностью:\u003Cbr\u003EНедавно перенесенный инфаркт миокарда, нестабильная стенокардия, артериальная гипертензия, тахикардия, судорожный синдром в анамнезе, повышение внутриглазного давления, закрытоугольная глаукома, маниакальные состояния в анамнезе, предрасположенность к кровотечениям со стороны кожных покровов и слизистых оболочек, исходно сниженная масса тела.\u003Cbr\u003EОтмена препарата Велаксин: Как и при лечении другими антидепрессантами, резкое прекращение терапии венлафаксином - особенно после высоких доз препарата - может вызвать симптомы отмены, в связи с чем рекомендуется перед отменой препарата постепенно снизить его дозу. Длительность периода, необходимого для снижения дозы, зависит от величины дозы, продолжительности терапии, а также индивидуальной чувствительности пациента.\u003Cbr\u003EПри назначении таблеток Велаксин больным с непереносимостью лактозы следует учитывать содержание лактозы (56,62 мг в каждой таблетке 25 мг; 84,93 мг в каждой таблетке 37,5 мг; 113,24 мг в каждой таблетке 50 мг, 169,86 мг в каждой таблетке 75 мг).\u003Cbr\u003EУ больных с депрессивными расстройствами перед началом любой лекарственной терапии следует учитывать вероятность суицидальных попыток. Поэтому для снижения риска передозировки начальная доза препарата должна быть по возможности низкой, а пациент должен находиться под тщательным медицинским наблюдением.\u003Cbr\u003EУ пациентов с аффективными расстройствами при лечении антидепрессантами, в том числе венлафаксином, могут возникать гипоманиакальные или маниакальные состояния. Как и другие антидепрессанты, венлафаксин должен назначаться с осторожностью больным с манией в анамнезе. Такие пациенты нуждаются в медицинском наблюдении.\u003Cbr\u003EКак и другие антидепрессанты, венлафаксин должен назначаться с осторожностью больным с эпилептическими припадками в анамнезе. Лечение венлафаксином должно быть прервано при возникновении эпилептических припадков.\u003Cbr\u003EПациентов следует предупредить о необходимости немедленно обратиться к врачу при возникновении сыпи, уртикарных элементов или других аллергических реакций.\u003Cbr\u003EУ некоторых больных во время приема венлафаксина отмечено дозозависимое повышение артериального давления, в связи с чем рекомендуется регулярный контроль артериального давления, особенно в период уточнения или повышения дозировки.\u003Cbr\u003EМожет произойти повышение частоты сердечного ритма, особенно во время приема высоких доз. Рекомендуется осторожность при тахиаритмии.\u003Cbr\u003EПациенты, особенно пожилые, должны быть предупреждены о возможности возникновения головокружения и нарушения чувства равновесия.\u003Cbr\u003EКак и другие ингибиторы обратного захвата серотонина, венлафаксин может повысить риск кровоизлияний в кожу и слизистые оболочки. При лечении больных, предрасположенных к таким состояниям, необходима осторожность.\u003Cbr\u003EВо время приема венлафаксина, особенно в условиях дегидратации или снижения объема крови (в том числе у пожилых пациентов и больных, принимающих диуретики), может наблюдаться гипонатриемия и/или синдром недостаточной секреции антидиуретического гормона.\u003Cbr\u003EВо время приема препарата может наблюдаться мидриаз, в связи с чем рекомендуется контроль внутриглазного давления у больных, склонных к его повышению или страдающих закрытоугольной глаукомой.\u003Cbr\u003EВенлафаксин не исследован у пациентов, недавно перенесших инфаркт миокарда и страдающих декомпенсированной сердечной недостаточностью. Таким больным препарат следует назначать с осторожностью.\u003Cbr\u003EПроведенные до настоящего времени клинические испытания не выявили толерантности к венлафаксину или зависимости от него. Несмотря на это, как и при лечении другими препаратами, действующими на центральную нервную систему, врач должен установить тщательное наблюдение за пациентами для выявления признаков злоупотребления препаратом. Тщательный контроль и наблюдение необходимы для пациентов, имеющих в анамнезе такие симптомы.\u003Cbr\u003EЖенщины детородного возраста должны применять соответствующие методы контрацепции во время приема венлафаксина.\u003Cbr\u003EНесмотря на то, что венлафаксин не влияет на психомоторные и когнитивные функции, следует учитывать, что любая лекарственная терапия психоактивными препаратами может снизить способность вынесения суждений, мышления или выполнения двигательных функций. Об этом следует предупредить пациента перед началом лечения. При возникновении таких эффектов степень и длительность ограничений должны быть установлены врачом. Также не рекомендован прием алкоголя."},{"name":"Взаимодействие","value":"Одновременное применение ингибиторов моноаминоксидазы (МАО) и венлафаксина противопоказано. Прием препарата Велаксин можно начинать не менее чем через 14 дней после окончания терапии ингибиторами МАО. Если применялся обратимый ингибитор МАО (моклобемид), этот интервал может быть короче (24 часа). Терапию ингибиторами МАО можно начинать не менее чем через 7 дней после отмены препарата Велаксин.\u003Cbr\u003EВенлафаксин не влияет на фармакокинетику лития.\u003Cbr\u003EПри одновременном применении с имипрамином фармакокинетика венлафаксина и его метаболита О-десметилвенлафаксина (ОДВ) не изменяется.\u003Cbr\u003EГалоперидол: эффект последнего может усиливаться из-за повышения уровня препарата в крови при совместном применении.\u003Cbr\u003EПри одновременном применении с диазепамом фармакокинетика препаратов и их основных метаболитов, существенно не изменяются. Также не обнаружено влияния на психомоторные и психометрические эффекты диазепама.\u003Cbr\u003EПри одновременном применении с клозапином может наблюдаться повышение его уровня в плазме крови и развитие побочных эффектов (например, эпилептических припадков).\u003Cbr\u003EПри одновременном применении с рисперидоном (несмотря на увеличение AUC рисперидона) фармакокинетика суммы активных компонентов (рисперидона и его активного метаболита) существенно не изменялась.\u003Cbr\u003EУсиливает влияние алкоголя на психомоторные реакции.\u003Cbr\u003EНа фоне приема венлафаксина следует соблюдать особую осторожность при электросудорожной терапии, так как опыт применения венлафаксина в этих условиях отсутствует.\u003Cbr\u003EЛекарственные препараты, метаболизируемые изоферментами цитохрома Р 450:\u003Cbr\u003EФермент CYP2D6 системы цитохрома Р 450 преобразует венлафаксин в активный метаболит О-десметилвенлафаксин (ОДВ). В отличие от многих других антидепрессантов, дозу венлафаксина можно не снижать при одновременном введении с препаратами, подавляющими активность CYP2D6, или у пациентов с генетически обусловленным снижением активности CYP2D6, поскольку суммарная концентрация активного вещества и метаболита (венлафаксина и ОДВ) при этом не изменится.\u003Cbr\u003EОсновной путь выведения венлафаксина включает метаболизм с участием CYP2D6 и CYP3A4; поэтому следует соблюдать особую осторожность при назначении венлафаксина в сочетании с лекарственными препаратами, угнетающими оба эти фермента. Такие лекарственные взаимодействия еще не исследованы.\u003Cbr\u003EВенлафаксин - относительно слабый ингибитор CYP2D6 и не подавляет активность изоферментов CYP1А2, CYP2C9 и CYP3A4; поэтому не следует ожидать его взаимодействия с другими препаратами, в метаболизме которых участвуют эти печеночные ферменты.\u003Cbr\u003EЦиметидин подавляет метаболизм \"первого прохождения\" венлафаксина и не оказывает влияние на фармакокинетику О-десметилвенлафаксина. У большинства пациентов ожидается лишь незначительное повышение общей фармакологической активности венлафаксина и О-десметилвенлафаксина (более выражено у пожилых пациентов и при нарушении функции печени).\u003Cbr\u003EКлинически значимые взаимодействия венлафаксина с антигипертензивными (в том числе бета-блокаторами, ингибиторами АПФ и диуретиками) и противодиабетическими препаратами не обнаружены\u003Cbr\u003EЛекарственные препараты, связанные с белками плазмы крови: связывание с белками плазмы составляет 27% для венлафаксина и 30% для ОДВ. Поэтому не влияет на концентрацию лекарственных средств в плазме крови, обладающих высокой степенью связывания с белками.\u003Cbr\u003EПри одновременном приеме с варфарином может усиливаться антикоагулянтный эффект последнего.\u003Cbr\u003EПри одновременном приеме с индинавиром изменяется фармакокинетика индинавира (с 28%-ным уменьшением площади под кривой AUC и 36%-ным снижением максимальной концентрации Сmax), а фармакокинетика венлафаксина и ОДВ не изменяется. Однако клиническое значение этого эффекта неизвестно."},{"name":"Регистрационный номер","value":"ЛC-000318"},{"name":"Дата государственной регистрации","value":"14.08.2019"},{"name":"Владелец регистрационного удостоверения","value":"Egis Pharmaceuticals"},{"name":"Изготовитель","value":"Egis"},{"name":"Фасовщик","value":"Egis"},{"name":"Страна бренда","value":"Венгрия"},{"name":"Страна-производитель","value":"Венгрия"},{"name":"Название препарата","value":"Велаксин"},{"name":"Срок годности","value":"60 мес."}]}],"transitionId":"tr_7209329573938637887"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом. Отпускается по рецепту врача. Приобретение лекарственных препаратов осуществляется только в торговом зале аптеки

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{"widgets":{"@marketfront/VisibilityLoaderMarket":{"/content/page/fancyPage/heroBannerCarousel/heroBannerCarousel":{"pageId":"market:product","offset":3000,"epicModeForLazyLoad":"default","widgetId":"HeroBannerCarousel","__zoneName":""}}},"meta":{"/content/page/fancyPage/heroBannerCarousel/heroBannerCarousel":{"name":"@marketfront/VisibilityLoaderMarket"}}}
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Ещё может подойти

  • 5-HTP капс., 50 мг, 0.44 г, 30 шт., 1 уп.
    –55 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-khc6jwhhe6/toggleWishlist":{"skuId":"101838504846","productId":1774398206,"offerId":"OqUca93cG3lIzI3av8SMsw","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ0PrGmbGP0oMmEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcI/tWMzgYQjoexsPsCGPHJtgQg7dnBBw==","sign":"VYdOI+R8lKvRT/5OCN4unbQZZJqIuee/4qPT6ai3fGU="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-khc6jwhhe6/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    5-HTP капс., 50 мг, 0.44 г, 30 шт., 1 уп.

    Рейтинг товара: 4.7 из 5
    на основе 88 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 689 ₽ вместо 710
    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капс., 50 мг, 0.44 г, 30 шт., 1 уп.","label":"2c00vsenxn6","count":0,"features":[],"imageMeta":{"namespace":"mpic","groupId":7979270,"key":"img_id2925668237767584805.jpeg"}},"quantity":{"step":1,"minimum":1,"maximum":999},"cpaUrl":"/safeclick/data=TxNGOK9vJEN7oLFLeCTKEkrTZoQadGRtjQLqzTxCAYEl31AulbEt2oxAF8ImTSmq4nimXoUQnWqG1OZsyd6j1rL8rBuOEHunXImk_nm2PWM-ezc84lFmmaQY0NRXu4W-HeIKVa3JAX0h3ZhWz6Puqoa5d2HA1gczPQuYT0pgiqq51HdxIl6jqYqQluydmnk4NBut1SvnhQnJG_2eIwYoOLE7UaYuxYaz7geo-E-zuC5BVa3G09Zoi9WY9FfZPjDK9z3DgpTOxT1NyFah1Nz275aEVUbfYL4xoW0Wfa4V_9_UwEx_KT0bG1mY868Aw1kieSnjAIXN3o-agsdePMMkiGI8RrjFyfbsNprRZSfF5U1Fw-pGosgbhCgxE3_d1I2EBwziPIkqFgIhGj3eKSJByw_rKYu1Fy0codj24nZoMVW53frQWunf9_1r-pyfhohxXbU8KhoWg0tFhZC2NMX5_Bh0ZHjpkGS3cuMLUcmVFOcBLGbXS9cE4NSXZyjrKgjm210igJLeXW9mX18BoU3GNrrIq5_21P3K-tlesc2dpB3Js1LIgk_bVKohHcQyWUXEe0fLN9vx-u2kxz9WARUfg8sEx38ammsWbdsR8Vn3vCQ1H0lGBS0gD61n2zptAM5qDUNsOj44uA9Y776sQ4JvCHt_sIUJwvUnxvaCwr1QNlgwDQ17oIHutQKufV-qzE2MQUBLdWQXlZyrQe2U0-tWL--DqMG_RhrX2QmAt8ul6wdcPnQEUPOf89c2zH6mXvk_iYTlFz5vgnKknNCLn0ODmojicDw6gvRcMIJamrBTHzuP5cJAYz-Ua77MGQGjvTNMdgUW7rr694rjUxXtOB7aS9rjRSGX6zIiMX8xU-cOUNmJaACUgb1rM8L0zQgTauFpoDhiUFPywSUKWEqMEakL1IMTDzioYOzGEtTC4XlajudyYhzkuYr9o4oELvItWk_wcMofiPnHPWqPP8qH3-RJQC8TFydD9_mmmxlSaTP3RVm-lrhS9-B_-XysLAJ5ldZC6k20a-sKvA5-UBiQruUWphlGKUnK_wxJI55uOE_7DlZ-GJzgJRaH7ptNK7AdDE6ZtZibgIjrxEO9k0C6kN5g8UISxGeek_T3SkvNvFm7ms6--uAfPze7cyiFjo6wom_SaFr9atSVbLVx0A7zu3OGBO7XJ2WGBtowCZYmYqzWDf1VwIgpMCIyEh8zY5Hh7-BQTllT2QnNya2dfqtccPJd_Rh5AIasKYyLSFAyDUPiTMnDFawQFD6Hy19EprUX_taZ6qsrKsjjAWqK_1Td1A1AX3R0ymgAFYWFPfZdQnsUgckrBEMQ4-uwcNbyf1nc34-btDeF4Bdspe2jmuKM01C1TaFKIcCzlnoHrEhnw1rZPx5h9qiSHKxhZTRF8N8zy19I2voS4tFHKKAaOceiW1pgD4UHxEY17EiW_Ujb2j3DGOEISR-kd3OWCQ2v-Ze5Bq6dQeK_RwQCeePmS6p4B2yO8nnxTcTQ94ZuUCI2RBixhjODcuK-1h2O5pBcg7Mn2YCPBi3gmCAHt8y0iCYhS27BSAstBiDS4yeGV3GY2TwmV0IJdXAyBBIh6U1RfjSoEn77u1Fz0X40DpjCK20UwTE9IsVBtTIXz42dOG7pYpr6wPxsKJvVEehnMo7IQVHoLTR3UnRPYfUiM54E6KzjjvnFdIJ0ZKMJUpWhtGewZa7mo5vqMUMQUKrPTgpjNih1D8u0THMXJ55xGc1wLuw2h9uxBzpq1cXiQMmvnsvjCJkpgWPZnsk09zHOhZLP5Bbm2NbL-YYvfn-SXN-JL_F_B7QUDCKoHaL3nmAvSFFkAXCS5r87l9xG8xq2VZNMce-Z1LHYKh-7Eti_JEael7rtgKduFuIz9tSbiTV8MSjdyUwo_jxjq88tAkHPWhUDkKxHIRDp64somKY-ZufUq3U8-FeR402CzQ1r9OOiKnJY41SpL6GIuqxt30DqAD6N8QFuelvbX4WWyY4VztyyUVHL2OjtBzz01uGT_VxRIM9J_0lwuWOCWQ35Ae0cPPEI-u5iodb5lKuNJ_HEtmCbY5mSGpl9uH7KkbdMe8n1NfP0e9mwPlV_KWwc8roPOrV0s_npVnJ4gFzYyALaJzFy6jVUPXYywSQ-onpCGGv9kyNxIFs9oMf9QyRtMKQ9tYp5Xk330ttQ8wKsSvohyd0KNI6O4Ihs92lm_xwx7UOnIvotObZyvN9plPlOf-zDy4ivh8JvT2uorTcnBAKV8W2ZYtobY3rrXLxnPOWb185DpSpGVwAZfqOHnZgVOAV_4n71Iu0fHeT0Cxdw1u6rAYcs89qnkr1-Oe8Cxbi_N3x2NyRo72kpUZY_8KgxrG3zt7I36eFfkL8pRsMcKXPUqDimp5zntJ8ckCNNBSDRYxmuTUdNlE_RPSJNhJd7jFODwWF5tPluAsKXbmsZqW6Vmh7P5H01hU9jby1yBJaA0QHIX-HdYVEyWnhsRSbgHf3286XxEF337f_Kxb-f97DM3OmpLweHV0YUat80tMcBZJNgSKgrGkWVo-71CNQfkpjZnPFFFiPbWbyGGOk5MwJV4pmVrdNJqR3OAMNYNCRHP4C9JyLSq2GbD5cof-ZCU7QwMXWb8ZyhCMq70tAYji2M4-eWX1SON6DPHhVO1ZxPfI4eCH6RgPmrqAPgZuHch0iUYki0C1vm5PW2UK_GsiKh1fcUFeq3kz_EyPb-L0jiS_mr49xH2c3fDOFdDjPNrgpqLuQrHSNb9nF7YJcgDg4Xfjq8VkVMt6ZYjQYCJf-T-41C4ztF1eoogptSK8OQhG9H1ZQwLPMCNng99N3rSvIzO9Wl5vV4dwwh4rc9orpFfaQmzkt1VI4q7xVN6ITQiGmPLV3HMRXiMHG-XsImMpf1bViR1OAumrMQAR3Gw4957LlMrJG2Xz7sWsdizCF9FSjZ8AWIEiMB6aXF3MJRvejRp_E4kgrDq8XOT7aKxGlleIA7zb3uiOdFlk1oOiyL6oA66igghb5grebW0FdFSHJmidgy--PdS7zRa_QfPpoMszt8LUzE6JHWb8wTVNDAZ1wNPO7TQjH2GbU4IayTgi5r_ZJjp4zbbmq2cexspW1B-0zQMVCiA8aRXk4rw2nER-Hu0jPN3CltGi8aPDncv-psgFb8loVy9xIMYiwWGHnaCCwmBrXoY0sKACbJssYdtxuACXKX4opuGiiAPmiYk_stmIPr1lT7ME1w7smYcTcl1psPyEFfF00Js38fhB0LgFZ6Lr8LMzNbRDrtS9NlVac55P9SvwxSeTOQVDylvWYzi5XvBBwDGQEDCeWwiANCm-JyRV4cSXAWqMbkQm6YgI00BE9PvNYjh_OA5TZsHdrjBzeu7fs5dHg__MzWHOMJV3_Qi8Zangqsdj3Mf_ZN8gkl7nVGYbsNu5FtepKEmsbcW3aYzXucSsSaOBOvEXUlt-v1aDd7A171GjI2fRADPaavwv4l_7f4EzZUdLZyroml1keiNKSDBx8FvKMD59yf85-6mYNUgZivxpJRyEbCknmbRt3dhh2g6Qrvy2oSqHtTVtbuXaYxcvi8P6PMCGKZm9Fe_QfBE7ZfnKkkypL51f7qYyrWrplcspew3JbldUlO2G02yq2ZeUljveavt3XsokSPxfZzJCre6gtUxIxryAAgSvy6JS_eQ1DqdyOlqwLIi5jIG7tF2n5j1xmpfRCbaad2xgiJF36PtvIsuPsSOUJh095aTOQsTb45vpp8QfmEKIW0fL9VDPv4v6E,/b64e=1/sign=5fbc35ed76370e84e3cff84dc5258f2a/keyno=MARKET_1/*","showUid":"17184403812002784563206001","cartLink":"/my/cart","showNotificationWhenDeleteItem":true,"isLavka":false,"isError":false,"isEats":false,"isCR":false,"isM2bEdoOnlyEnable":false,"isEatsMarketIntegration":true,"isCartButtonNext":false,"isUpsalePopupCRExp":false,"baobabClientDataAdditionToCart":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ0PrGmbGP0oMmEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcI/tWMzgYQjoexsPsCGPHJtgQg7dnBBw==","sign":"VYdOI+R8lKvRT/5OCN4unbQZZJqIuee/4qPT6ai3fGU="},"target":"cart_addition"},"baobabClientDataDeletionFromCart":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ0PrGmbGP0oMmEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcI/tWMzgYQjoexsPsCGPHJtgQg7dnBBw==","sign":"VYdOI+R8lKvRT/5OCN4unbQZZJqIuee/4qPT6ai3fGU="},"target":"cart_deletion"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-khc6jwhhe6/addToCartBu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  • Natrol Melatonin таб., 3 мг, 110 г, 240 шт.
    –1 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-own26w2gtp/toggleWishlist":{"skuId":"101581401732","productId":1467295415,"offerId":"2gYJN_FIwhmRWMd4rWFo6w","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ0PrGmbGP0oMmEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIt83UuwUQhN3ktfoCGNau7BEg7dnBBw==","sign":"T/OetHb3PU+eDm0x0TIx3J0ID5Y7E9k0wlCXEYs0lkA="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-own26w2gtp/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Natrol Melatonin таб., 3 мг, 110 г, 240 шт.

    Рейтинг товара: 5 из 5
    на основе 10 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 3 485 ₽ вместо 3 520
    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Melatonin таб., 3 мг, 110 г, 240 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  • Когнивия фосфатидилсерин капс., 60 шт., 1 уп.
    –21 %
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    Когнивия фосфатидилсерин капс., 60 шт., 1 уп.

    Рейтинг товара: 4.7 из 5
    на основе 173 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 2 820 ₽ вместо 2 848
    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  • Natrol Stress and Anxiety День и Ночь таб., 110 г, 60 шт.
    –1 %
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    Natrol Stress and Anxiety День и Ночь таб., 110 г, 60 шт.

    Рейтинг товара: 3 из 5
    на основе 2 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 4 074 ₽ вместо 4 115
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Stress and Anxiety День и Ночь таб., 110 г, 60 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  • GLS Триптофан капс., 500 мг, 0.25 г, 90 шт.
    –10 %
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    GLS Триптофан капс., 500 мг, 0.25 г, 90 шт.

    Рейтинг товара: 4.8 из 5
    на основе 23 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 540 ₽ вместо 550
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Триптофан капс., 500 мг, 0.25 г, 90 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  • Стрессанет таб., 45 г, 40 шт., 1 уп.
    ВАМ–46 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-nm9b6nx6e/toggleWishlist":{"skuId":"101694309052","productId":1488969440,"offerId":"IRZ3Pmi7svhvuhBmGpoGGQ","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ0PrGmbGP0oMmEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcI4L3/xQUQvIXQ6/oCGL+R9wcg7dnBBw==","sign":"steUQujzSeocmVP4bjm26u6knvR/Jc7niPXHoKhL+Xg="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-nm9b6nx6e/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Стрессанет таб., 45 г, 40 шт., 1 уп.

    Рейтинг товара: 4.7 из 5
    на основе 15 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 576 ₽ вместо 588
    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таб., 45 г, 40 шт., 1 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  • Релаксозан День таб., 40 шт.
    –2 %
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    Релаксозан День таб., 40 шт.

    Рейтинг товара: 4.7 из 5
    на основе 124 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 669 ₽ вместо 683
    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  • Формула Спокойствия Триптофан капс., 15 шт.
    –1 %
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    Формула Спокойствия Триптофан капс., 15 шт.

    Рейтинг товара: 4.6 из 5
    на основе 29 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 452 ₽ вместо 457
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  • Гинкго Билоба Эвалар таб., 0.5 г, 60 шт., 1 уп.
    –2 %
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    Гинкго Билоба Эвалар таб., 0.5 г, 60 шт., 1 уп.

    Рейтинг товара: 3 из 5
    на основе 2 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 1 507 ₽ вместо 1 537
    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Билоба Эвалар таб., 0.5 г, 60 шт., 1 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  • Релаксен капс., 30 шт.
    –1 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ejf5ws3t1rv/toggleWishlist":{"skuId":"227814429","productId":1778172885,"offerId":"bVVCa6t8uF0mkVxIhHEXmg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ0PrGmbGP0oMmEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUI1YfzzwYQndjQbBif3tAHIO3ZwQc=","sign":"HAtU2zKSEiyBOthn/R/omIhg+SvJeaVliVo3NciofSk="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-ejf5ws3t1rv/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Релаксен капс., 30 шт.

    Рейтинг товара: 5 из 5
    на основе 3 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 277 ₽ вместо 280
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  • Гинкго Билоба таб., 100 г, 90 шт., нейтральный, 1 уп.
    –1 %
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    Гинкго Билоба таб., 100 г, 90 шт., нейтральный, 1 уп.

    Рейтинг товара: 4.8 из 5
    на основе 5 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 10 247 ₽ вместо 10 350
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Инструкция

Показания к применению

Депрессии различной этиологии, лечение и профилактика.

Противопоказания

Гиперчувствительность.
Одновременный прием ингибиторов МАО (см. также раздел "Взаимодействие").
Тяжелые нарушения функции почек и/или печени (скорость клубочковой фильтрации менее (СКФ) 10 мл/мин).
Возраст до 18 лет (безопасность и эффективность для этой возрастной группы не доказаны).
Установленная или подозреваемая беременность.
Период лактации.

Способ применения и дозы

Таблетки Велаксина рекомендуется принимать во время еды.
Рекомендуемая начальная доза составляет 75 мг в два приема (по 37,5 мг) ежедневно. Если после нескольких недель лечения не наблюдается значительного улучшения, суточную дозу можно повысить до 150 мг (2 х 75 мг в день).
Если, по мнению врача, необходима более высокая доза (тяжелое депрессивное расстройство или другие состояния, требующие стационарного лечения), можно сразу назначить 150 мг в два приема (2 х 75 мг в день). После этого суточную дозу можно увеличивать на 75 мг каждые 2-3 дня до достижения желаемого терапевтического эффекта.
Максимальная суточная доза препарата Велаксин составляет 375 мг. После достижения необходимого терапевтического эффекта суточная доза может быть постепенно снижена до минимального эффективного уровня.
Поддерживающая терапия и профилактика рецидивов:
Поддерживающее лечение может продолжаться 6 месяцев и более. Назначаются минимальные эффективные дозы, применявшиеся при лечении депрессивного эпизода.
Почечная недостаточность: при легкой почечной недостаточности (скорость клубочковой фильтрации (СКФ) более 30 мл/мин) коррекция режима дозирования не требуется. При умеренной почечной недостаточности (СКФ 10-30 мл/мин) дозу следует снизить на 25-50%. В связи с удлинением периода полувыведения венлафаксина и его активного метаболита (ОДВ), таким пациентам следует принимать всю дозу один раз в день. Не рекомендуется применять венлафаксин при тяжелой почечной недостаточности (СКФ менее 10 мл/мин), поскольку надежные данные о такой терапии отсутствуют. Пациенты на гемодиализе могут получать 50% обычной суточной дозы венлафаксина после завершения гемодиализа.
Печеночная недостаточность: при легкой печеночной недостаточности (протромбиновое время (ПВ) менее 14 сек) коррекция режима дозирования не требуется. При умеренной печеночной недостаточности (ПВ от 14 до 18 сек) дозу следует снизить на 50%. Не рекомендуется применять венлафаксин при тяжелой печеночной недостаточности, поскольку надежные данные о такой терапии отсутствуют.
Пожилые пациенты: сам по себе пожилой возраст пациента не требует изменения дозы, однако (как и при назначении других лекарственных препаратов) при лечении пожилых пациентов требуется осторожность, например, в связи с возможностью нарушения функции почек. Следует применять наименьшую эффективную дозу. При повышении дозы пациент должен находиться под тщательным медицинским наблюдением.
Прекращение приема препарата Велаксин
По окончании приема препарата Велаксин рекомендуется постепенно снижать дозировку препарата, по крайней мере в течение недели, и наблюдать за состоянием пациента для того, чтобы свести к минимуму риск, связанный с отменой препарата (см. ниже).
Период, требуемый для полного прекращения приема препарата, зависит от его дозировки, длительности курса лечения и индивидуальных особенностей пациента.
Полная инструкция
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Велаксин таб.
Велаксин таб., 75 мг, 28 шт.
5.0
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5.0
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    Цена 774 ₽ вместо 1 890
  • GLS Триптофан капс., 500 мг, 0.25 г, 90 шт.
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    GLS Триптофан капс., 500 мг, 0.25 г, 90 шт.

    Цена 540 ₽ вместо 600
  • Гилан ультра комфорт увлажн. гл. р-р, 0.3%, 0.4 мл, 50 г, 10 шт.
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    Гилан ультра комфорт увлажн. гл. р-р, 0.3%, 0.4 мл, 50 г, 10 шт.

    Цена 288 ₽ вместо 331
  • 5-HTP капс., 50 мг, 0.44 г, 30 шт., 1 уп.
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    5-HTP капс., 50 мг, 0.44 г, 30 шт., 1 уп.

    Цена 689 ₽ вместо 1 546
  • Формула Спокойствия Триптофан капс., 15 шт.
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    Формула Спокойствия Триптофан капс., 15 шт.

    Цена 452 ₽ вместо 457
  • Релаксен капс., 30 шт.
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    Релаксен капс., 30 шт.

    Цена 277 ₽ вместо 280
  • Эвалар Чай Эвалар БИО при повышенном содержании мочевой кислоты, 20 фильтр-пакетов
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    Эвалар Чай Эвалар БИО при повышенном содержании мочевой кислоты, 20 фильтр-пакетов

    Цена 194 ₽ вместо 224
  • Скин-кап аэрозоль фл., 0,2 %, 35 мл, 35 г, 1 уп.
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    Скин-кап аэрозоль фл., 0,2 %, 35 мл, 35 г, 1 уп.

    Цена 2 471 ₽ вместо 4 800
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    Реклама
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  • Стрессанет таб., 45 г, 40 шт., 1 уп.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1488969440_9/content/content/gallery":{"title":"Стрессанет таб., 45 г, 40 шт., 1 уп.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/5236802/img_id2397783228900437837.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5236802/img_id2397783228900437837.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5236802/img_id2397783228900437837.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5236802/img_id2397783228900437837.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5236802/img_id2397783228900437837.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5236802/img_id2397783228900437837.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/1865652/img_id6134482140215756494.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/1865652/img_id6134482140215756494.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/1865652/img_id6134482140215756494.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/1865652/img_id6134482140215756494.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/1865652/img_id6134482140215756494.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/1865652/img_id6134482140215756494.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/3721790/img_id1977321227902089118.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/3721790/img_id1977321227902089118.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/3721790/img_id1977321227902089118.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/3721790/img_id1977321227902089118.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/3721790/img_id1977321227902089118.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/3721790/img_id1977321227902089118.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4303516/img_id2293157688078404169.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4303516/img_id2293157688078404169.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4303516/img_id2293157688078404169.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4303516/img_id2293157688078404169.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4303516/img_id2293157688078404169.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4303516/img_id2293157688078404169.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/11563949/img_id8100363264279139159.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/11563949/img_id8100363264279139159.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/11563949/img_id8100363264279139159.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/11563949/img_id8100363264279139159.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/11563949/img_id8100363264279139159.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/11563949/img_id8100363264279139159.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/11368503/img_id3722838974585260382.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/11368503/img_id3722838974585260382.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/11368503/img_id3722838974585260382.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/11368503/img_id3722838974585260382.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/11368503/img_id3722838974585260382.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/11368503/img_id3722838974585260382.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ0PrGmbGP0oMmEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIXCOC9/8UFELyF0Ov6Ahi/kfcHIO3ZwQc=","sign":"4M3Dl0ee+6akIjVN8/lQhyUDzODIV1Ux1yqO2tXlTp0="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1488969440_9/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1488969440_9/content/content/toggleWishlist":{"skuId":"101694309052","productId":1488969440,"offerId":"pJwWvRq0e-tvRfCn3nD_7w","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ0PrGmbGP0oMmEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIXCOC9/8UFELyF0Ov6Ahi/kfcHIO3ZwQc=","sign":"4M3Dl0ee+6akIjVN8/lQhyUDzODIV1Ux1yqO2tXlTp0="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1488969440_9/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Стрессанет таб., 45 г, 40 шт., 1 уп.

    Цена 488 ₽ вместо 493
  • Релаксозан День таб., 20 шт.
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    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1404748725_10/content/content/toggleWishlist":{"skuId":"662926015","productId":1404748725,"offerId":"_d5U5CN1OOaKT6P66iWt5A","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ0PrGmbGP0oMmEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCLWH650FEL/ljbwCGNW7oQYg7dnBBw==","sign":"NQ6aQdERfosANvuR61aq1mT6ka5qzfFB0bboFoj3aFA="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1404748725_10/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Релаксозан День таб., 20 шт.

    Цена 488 ₽ вместо 493
  • БиоГая Пробиотик капли детск. фл., 5 мл, 1 уп.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:997279548_11/content/content/gallery":{"title":"БиоГая Пробиотик капли детск. фл., 5 мл, 1 уп.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/5131700/img_id5468924246027050142.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5131700/img_id5468924246027050142.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5131700/img_id5468924246027050142.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5131700/img_id5468924246027050142.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5131700/img_id5468924246027050142.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5131700/img_id5468924246027050142.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/4408567/img_id147222889702037708.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/4408567/img_id147222889702037708.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/4408567/img_id147222889702037708.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/4408567/img_id147222889702037708.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/4408567/img_id147222889702037708.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/4408567/img_id147222889702037708.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQ0PrGmbGP0oMmEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIXCLyOxdsDEPTRh9H5Ahj03/kHINrZwQc=","sign":"/2t7WzwMf1DRgIw4ds+c3N/6Hj1FLvUOHmWLEZMjo+8="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:997279548_11/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
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    БиоГая Пробиотик капли детск. фл., 5 мл, 1 уп.

    Цена 1 752 ₽ вместо 3 500
  • Natrol Melatonin таб., 3 мг, 100 г, 60 шт.
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    Natrol Melatonin таб., 3 мг, 100 г, 60 шт.

    Цена 1 558 ₽ вместо 2 150
  • Пастилки California Gold Nutrition Vitamin D3 gummies со вкусом фруктов и ягод, 280 г, 90 шт.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1780868129_13/content/content/gallery":{"title":"Пастилки California Gold Nutrition Vitamin D3 gummies со вкусом фруктов и ягод, 280 г, 90 шт.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/5221216/img_id7471792949168823942.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5221216/img_id7471792949168823942.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5221216/img_id7471792949168823942.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5221216/img_id7471792949168823942.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5221216/img_id7471792949168823942.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5221216/img_id7471792949168823942.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 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    Пастилки California Gold Nutrition Vitamin D3 gummies со вкусом фруктов и ягод, 280 г, 90 шт.

    Цена 2 005 ₽ вместо 2 800
  • Гинкго Билоба Эвалар таб., 0.5 г, 40 шт., 1 уп.
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    Гинкго Билоба Эвалар таб., 0.5 г, 40 шт., 1 уп.

    Цена 428 ₽ вместо 432
  • Ревмафлекс капс., 60 шт., нейтральный, 1 уп.
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    Ревмафлекс капс., 60 шт., нейтральный, 1 уп.

    Цена 772 ₽ вместо 950
  • Фенистил гель д/нар. прим., 0.1%, 8 мл, 30 г
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    Фенистил гель д/нар. прим., 0.1%, 8 мл, 30 г

    Цена 585 ₽ вместо 591
  • Когнивия фосфатидилсерин капс., 60 шт., 1 уп.
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    Когнивия фосфатидилсерин капс., 60 шт., 1 уп.

    Цена 2 820 ₽ вместо 3 560
  • Кленбутерол Софарма таб., 0.02 мг, 50 шт.
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    Кленбутерол Софарма таб., 0.02 мг, 50 шт.

    Цена 686 ₽
  • ЛимфоТранзит концентрат напитка фл., 100 мл
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    ЛимфоТранзит концентрат напитка фл., 100 мл

    Цена 361 ₽ вместо 365
  • Гилан Комфорт увлажн. гл. р-р, 0.18%, 0.4 мл, 30 шт.
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    Гилан Комфорт увлажн. гл. р-р, 0.18%, 0.4 мл, 30 шт.

    Цена 396 ₽
  • {"widgets":{"@light/BannerCurtain":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_102_21/content/content/content/bannerCurtain":{"advertisementId":2064961,"impression":"/safeclick/data=SpQw45JhDGE6zDtOdUQO_FYdjjTRdthYLP8opDR-ZoVg71CHfxVuNy4gw23nif3sNQ9GK1gCnWlr-3-prplC1f2FuooGy-Bp5Wx9Tfk7n7VaZQv0PifA801YDIOj6SGSEqTVnipDZ6dvn4ah_Q3CnhT8bGLvQj4EXOM9eHEzyAysUpIj7Vo-tUW06kv0c82hxmC0aY0c3Sr2--gSuM8_DrJtECG6-vEWBU1_pCbkwDjEbLVQjDCJ98z4j1ytc2n7ciylV-cuDVTAvgMdGfc3TUwK3BU49Esvpqrm4O0Y9zEX3ge4e3YM2BJfUUVCwRQrNS2gO4eUM-OeT7qpapgzmjDtVfO5edpR8oaoQ11h1FnYTeRzSWc5yOQpNsS-lGU47FQ5xBZjmIkCBdIxO3HwZE24tQEtoXEH2ZSf1S5OlizvoxJclZkSzEeGyfhH8hwLar2ftudaxFghNagSi_StyTIug2oCM2oT-WstQsvqU1a0xKerZ2Z3p27iG7A6Y-vsNXkQWLCSl3oei_suqVhwpyrLO10g5lrf6obXvKderTYRrrOHuCxSgcoCZwnUsWL5YatPcXlAX9a0jTnvggH_Zrg9n7k4_lNTVTGjrPveJrTS82Ey3vyHPkhm7fJvhwde4f0pPuyz5TyDmxBNFNWIi-D8Jz48LSAm7IwAse7PD3cV-ymzD5B7K-wFodYhK9VY9EjxiqIhfuh2hUHcDUo7ZY0supRE3hO5ow16y1O1Sj5QGJxQMi13XT7Hbl1HBGP9en5a7xCbRdHaSEHPrf_5WurYBL0EeQ0IyVr5K_-qe7JfHwQnwZNyKyhJkrBZ3MZIHEpsAqXXne55iNd0m_yHnG1rZmp00vKHLkTKLQAt8G05Tqkr7PT36uWkDhiYkbDpqOWBB0K-0tsXGfJcsCgduR3SFU-5NmFNCJIlLvFFFYIMbbTVKLi13kxMdA_oQLrZtJ7uhdT4PcLAphE_yGn0TSPz4w3aav9qgfHeAe31DkNJtPNmiHsOkfNkibE2K74YNcOjr84qe296L3L_zoKNpMSqQR4_1KRtssmx91hjRkZM-sXNVmO2OhP8VV26CubqX8rJ86NZuxbxYfp2Itn-rg,,/b64e=1/sign=523a9af87e63317a68fb830841e29d41/keyno=MARKET_1/*"}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_102_21/content/content/content/bannerCurtain":{"name":"@light/BannerCurtain"}}}
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    Реклама
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  • Natrol Stress and Anxiety День и Ночь таб., 110 г, 60 шт.
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    Natrol Stress and Anxiety День и Ночь таб., 110 г, 60 шт.

    Цена 4 074 ₽ вместо 4 115
  • Гинкго Билоба таб., 100 г, 90 шт., нейтральный, 1 уп.
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    Гинкго Билоба таб., 100 г, 90 шт., нейтральный, 1 уп.

    Цена 10 247 ₽ вместо 10 350
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