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Велдексал таб. п/o плен., 25 мг, 10 шт.

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Коротко о товаре

Артикул Маркета
43489529
Тип препарата
Назначение
Действующее вещество
Возраст
от 18 лет
Инструкция
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очень редко — анафилактические реакции, включая анафилактический шок.\u003Cbr\u003E\u003Cbr\u003EНарушения со стороны обмена веществ и питания: редко - анорексия.\u003Cbr\u003E\u003Cbr\u003EНарушения психики: нечасто — бессонница, ощущение беспокойства.\u003Cbr\u003E\u003Cbr\u003EНарушения со стороны нервной системы: нечасто - головная боль, головокружение, сонливость; редко — парестезии, синкопальные состояния (преходящие кратковременные обмороки).\u003Cbr\u003E\u003Cbr\u003EНарушения со стороны органа зрения: очень редко - нечеткость зрения.\u003Cbr\u003E\u003Cbr\u003EНарушения со стороны органа слуха и лабиринтные нарушения: нечасто - вертиго; очень редко - шум в ушах.\u003Cbr\u003E\u003Cbr\u003EНарушения со стороны сердца: нечасто - ощущение сердцебиения, чувство жара, гиперемия кожных покровов; редко - повышение артериального давления; очень редко - тахикардия, снижение артериального давления.\u003Cbr\u003E\u003Cbr\u003EНарушения со стороны дыхательной системы, органов грудной клетки и средостения: редко - брадипноэ; очень редко - бронхоспазм, одышка.\u003Cbr\u003E\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта: часто - тошнота, рвота, боль в животе, диспепсия, диарея; нечасто - гастрит, запор, сухость во рту, метеоризм; редко - эрозивно-язвенные поражения желудочно-кишечного тракта (ЖКТ), кровотечение из язвы или ее перфорация; очень редко - поражение поджелудочной железы.\u003Cbr\u003E\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей: редко - гепатит, повышение активности «печеночных» ферментов, в том числе аспартатаминотрансферазы и аланинаминотрансферазы (ACT и АЛТ): очень редко - поражение печени.\u003Cbr\u003E\u003Cbr\u003EНарушения со стороны кожу и подкожных тканей: нечасто - кожная сыпь; редко — крапивница, угревая сыпь, потливость; очень редко - тяжелые кожные реакции (синдром Стивенса-Джонсона, токсический эпидермальный некролиз (синдром Лайелла)), ангионевротический отек, отек лица, аллергический дерматит, фотосенсибилизация, кожный зуд.\u003Cbr\u003E\u003Cbr\u003EНарушения со стороны скелетно-мышечной и соединительной ткани: редко - боль в спине.\u003Cbr\u003E\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей: редко - полиурия, острая почечная недостаточность; очень редко - нефрит или нефротический синдром.\u003Cbr\u003E\u003Cbr\u003EНарушения со стороны половых органов и молочной железы: редко — у женщин — нарушение менструального цикла, у мужчин - преходящее нарушение функции предстательной железы при длительном примеиенип.\u003Cbr\u003E\u003Cbr\u003EОбщие расстройства и нарушения, в месте введения: нечасто - повышенная утомляемость, астения, озноб, общее недомогание; очень редко - периферические отеки.\u003Cbr\u003E\u003Cbr\u003EКак и при применении других НПВП, возможно развитие следующих побочных эффектов: асептический менингит, возникающий преимущественно у пациентов с системной красной волчанкой или другими системными заболеваниями соединительной ткани, гематологические нарушения (тромбоцитопеническая пурпура, апластическая и гемолитическая анемии), редко - агранулоцитоз и гипоплазия костного мозга.\u003Cbr\u003E"},{"name":"Фармакологическое действие","value":"Декскетопрофена трометамол относится к нестероидным противовоспалительным препаратам (НПВП), оказывает обезболивающее, противовоспалительное и жаропонижающее действие. Механизм действия декскетопрофена основан па ингибировании синтеза простагландинов на уровне циклооксигеназ (ЦОГ-1 и ЦОГ-2).\u003Cbr\u003E\u003Cbr\u003EОбезболивающий эффект наступает через 30 мин после приема препарата внутрь, продолжительность терапевтического действия составляет 4-6 ч.\u003Cbr\u003E"},{"name":"Фармакологическая группа","value":"нестероидный противовоспалительный препарат (НПВП)"},{"name":"Форма выпуска","value":"таблетки, покрытые пленочной оболочкой"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Продолжительность действия","value":"4-6 часов"},{"name":"Условия хранения","value":"При температуре не выше 25 °C.\u003Cbr\u003E\u003Cbr\u003EХранить в недоступном для детей месте.\u003Cbr\u003E"},{"name":"Передозировка","value":"Симптомы: тошнота, анорексия, боль в животе, головная боль, головокружение, дезориентация, бессонница.\u003Cbr\u003E\u003Cbr\u003EЛечение: симптоматическая терапия, при необходимости - промывание желудка, прием активированного угля; гемодиализ малоэффективен.\u003Cbr\u003E"},{"name":"Применение при беременности и кормлении грудью","value":"Применение декскетопрофена при беременности и в период грудного вскармливания противопоказано."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В связи с возможным головокружением и сонливостью в период приема декскетопрофена, способность к концентрации внимания и быстрота психомоторных реакций у пациентов могут снижаться, особенно в первый час после приема препарата. Поэтому в период лечения декскетопрофеном следует соблюдать осторожность при управлении транспортными средствами и занятиях потенциально опасными вилами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"Нежелательные побочные эффекты можно свести к минимуму при применении препарата в наименьшей эффективной дозе при минимальной длительности применения, необходимой для купирования болевого синдрома.\u003Cbr\u003E\u003Cbr\u003EРиск возникновения осложнений со стороны ЖКТ повышается у пациентов с язвенным поражением ЖКТ в анамнезе, у пожилых пациентов, при увеличении дозы НПВП; поэтому применение декскетонрофена у этой категории пациентов следует начинать с наименьшей рекомендуемой дозы.\u003Cbr\u003E\u003Cbr\u003EПациентам вышеперечисленных категорий, а также пациентам, которым требуется одновременное применение низких доз ацетилсалициловой кислоты или других средств, повышающих риск возникновения осложнений со стороны ЖКТ, рекомендуется дополнительно одновременное применение гастропротекторов (мизопростол или блокаторы протонной помпы).\u003Cbr\u003E\u003Cbr\u003EУ пациентов, одновременно принимающих антиагреганты или антикоагулянты, глюкокортикостероиды, также повышается риск возникновения желудочно-кишечного кровотечения.\u003Cbr\u003E\u003Cbr\u003EПациенты с нарушениями со стороны желудочно-кишечного тракта или желудочно-кишечными заболеваниями в анамнезе должны находиться под тщательным медицинским наблюдением. В случае возникновения желудочно-кишечного кровотечения или язвенного поражения терапию декскетопрофеном следует отменить.\u003Cbr\u003E\u003Cbr\u003EДекскетопрофен следует применять с осторожностью у пациентов с желудочно-кишечными заболеваниями в анамнезе (язвенный колит, болезнь Крона), поскольку возможно обострение этих заболеваний.\u003Cbr\u003E\u003Cbr\u003EВсе НПВП могут ингибировать агрегацию тромбоцитов и увеличивать время кровотечения за счет ингибирования синтеза простагландинов. В связи с этим применение декскетопрофена у пациентов, одновременно принимающих препараты, влияющие на систему гемостаза, такие как варфарин, производные кумарина и гепарины, не рекомендовано.\u003Cbr\u003E\u003Cbr\u003EКак и другие НПВП, декскетопрофен может приводить к повышению концентрации креатинина и азота в плазме крови. Как и другие ингибиторы синтеза простагландинов, декскетопрофен может оказывать побочное действие на мочевыделительную систему, что может привести к развитию гломерулонефрита, интерстициального нефрита, папиллярного некроза, нефротического синдрома и острой почечной недостаточности. Следует соблюдать осторожность при применении препарата у пациентов, одновременно применяющих диуретики и пациентов, у которых возможно развитие гиповолемии, в связи с повышенным риском нефротоксичности.\u003Cbr\u003E\u003Cbr\u003EКак и при применении других НПВП. па фоне терапии текскетопрофеном может наблюдаться небольшое преходящее повышение активности «печеночных» ферментов. У пациентов пожилого возраста необходим контроль функции печени и почек. В случае значительного повышения соответствующих показателей декскетопрофен следует отменить.\u003Cbr\u003E\u003Cbr\u003EКак и другие НПВП, декскетопрофен может маскировать симптомы инфекционных заболеваний. В случае обнаружения признаков инфекции или ухудшения самочувствия на фоне терапии декскетопрофеном пациенту необходимо сразу обратиться к врачу.\u003Cbr\u003E\u003Cbr\u003EПрепарат может вызывать задержку жидкости в организме, поэтому у пациентов с артериальной гипертензией, с почечной и/или сердечной недостаточностью декскетопрофен следует применять с особой осторожностью. В случае ухудшения состояния применение препарата необходимо прекратить.\u003Cbr\u003E\u003Cbr\u003EУ пациентов с неконтролируемой артериальной гипертензией. ишемической болезнью сердца, застойной сердечной недостаточностью, заболеваниями периферических артерий и/или цереброваскулярными заболеваниями препарат следует применять с осторожностью. Аналогичный подход применим к пациентам с факторами риска развития сердечно-сосудистых заболеваний (артериальная гипертензия, гиперлипидемия, сахарный диабет, курение).\u003Cbr\u003E\u003Cbr\u003EНеобходимо соблюдать осторожность при назначении декскетонрофена пациентам с наличием в анамнезе сердечно-сосудистых заболеваний, особенно пациентам с сердечной недостаточностью, в связи с возможным риском прогрессирования.\u003Cbr\u003E\u003Cbr\u003EКлинические исследования и эпидемиологические данные позволяют сделать вывод о том, что НПВП, особенно в высоких дозах и при длительном применении, могут приводить к незначительному риску развития острого инфаркта миокарда или инсульта. Для исключения риска данных событий при применении декскетопрофена данных недостаточно.\u003Cbr\u003E\u003Cbr\u003EПожилые пациенты особенно подвержены неблагоприятным реакциям при применении НПВП, в том числе, риску возникновения желудочно-кишечных кровотечений и перфораций, угрожающим жизни пациента, снижению функций почек, печени и сердца. При применении декскетопрофена у данной категории пациентов необходим надлежащий клинический контроль.\u003Cbr\u003E\u003Cbr\u003EИмеются данные о возникновении редких случаев кожных реакций (таких как эксфолиативный дерматит, синдром Стивенса-Джонсона, токсический эпидермальный некролиз) при применении НПВП. При первых проявлениях кожной сыпи, поражении слизистых оболочек или других признаках аллергической реакции прием декскетопрофена следует немедленно прекратить и обратиться к врачу.\u003Cbr\u003E\u003Cbr\u003EС осторожностью:\u003Cbr\u003EЯзвенная болезнь желудка и двенадцатиперстной кишки, язвенный колит, болезнь Крона, заболевания печени в анамнезе, печеночная порфирия, хроническая болезнь почек, стадия 2 (СКФ 60-89 мл/мин/1,73 м2), хроническая сердечная недостаточность, артериальная гипертензия, значительное снижение объема циркулирующей крови (в том числе после хирургического вмешательства), пожилые пациенты старше 65 лет (в том числе получающие диуретики, ослабленные пациенты и пациенты с низкой массой тела), бронхиальная астма, одновременный прием глюкокортикостероидов (в том числе преднизолона), антикоагулянтов (в том числе варфарина), антиагрегантов (в том числе ацетилсалициловой кислоты, клопидогрела), селективных ингибиторов обратного захвата серотонина (в том числе циталопрама, флуоксетина, пароксетина, сертралина), ишемическая болезнь сердца. цереброваскулярные заболевания, дислипидемия/гиперлипидемия, сахарный диабет, заболевания периферических артерий, курение, наличие инфекции Helicobacter pylori, системная красная волчанка (СКВ) и другие системные заболевания соединительной ткани, длительное применение НПВП, туберкулез, выраженный остеопороз, алкоголизм, тяжелые соматические заболевания.\u003Cbr\u003E"},{"name":"Взаимодействие","value":"Нижеследующие взаимодействия характерны для всех НПВП.\u003Cbr\u003E\u003Cbr\u003EНежелательные комбинации\u003Cbr\u003E\u003Cbr\u003EС другими НПВП, включая салицилаты в высоких дозах (более 3г в сутки): одновременное применение нескольких НПВП вследствие синергического эффекта повышает риск развития желудочно-кишечного кровотечения и язвы.\u003Cbr\u003E\u003Cbr\u003EС антикоагулянтами: декскетопрофен, как и другие НПВП, может усиливать эффект антикоагулянтов, таких как варфарин в связи с высокой степенью связывания с белками плазмы крови, ингибированием агрегации тромбоцитов и поражением слизистой оболочки желудочно-кишечного тракта. В случае необходимости одновременного применения необходим тщательный контроль за состоянием пациента и регулярный мониторинг лабораторных показателей.\u003Cbr\u003E\u003Cbr\u003EС гепарином: при одновременном применении повышается риск развития кровотечения (в связи с ингибированием агрегации тромбоцитов и повреждающим действием на слизистую оболочку желудочно-кишечного тракта). В случае необходимости одновременного применения необходим тщательный контроль за состоянием пациента и регулярный мониторинг лабораторных показателей.\u003Cbr\u003E\u003Cbr\u003EС глюкокортикостероидами: при одновременном применении повышается риск язвенного поражения желудочно-кишечного тракта и кровотечений.\u003Cbr\u003E\u003Cbr\u003EС препаратами лития: НПВП повышают концентрацию лития в плазме крови вплоть до токсической в связи с чем, данный показатель необходимо контролировать при одновременном применении с декскетопрофспом, изменении дозировки, а также после отмены НПВП.\u003Cbr\u003E\u003Cbr\u003EС метотрексатом в высоких дозах (15 мг в неделю и более): возможно повышение гематологической токсичности метотрексата в связи со снижением его почечного клиренса при одновременном применении с НПВП.\u003Cbr\u003E\u003Cbr\u003EС гидантоинами и сульфонамидами: возможно усиление их токсического действия.\u003Cbr\u003E\u003Cbr\u003EКомбинации, требующие осторожности\u003Cbr\u003E\u003Cbr\u003EС диуретиками, ингибиторами ангиотензинпреврсицающего фермента (АПФ), антибиотиками из группы аминогликозидов, антагонистами рецепторов апгиотензина-II: одновременное применение с НПВП связано с риском развития острой почечной недостаточности у обезвоженных пациентов (снижение клубочковой фильтрации, обусловленное сниженным синтезом простагландинов). При одновременном применении НПВП могут уменьшать антигипертензивный эффект некоторых препаратов. При одновременном применении декскетопрофена и диуретиков необходимо убедиться, что у пациента отсутствуют признаки обезвоживания, а также в начале одновременного применения контролировать функцию почек.\u003Cbr\u003E\u003Cbr\u003EС метотрексатом в низких дозах (менее 15 мг в неделю): возможно повышение гематологической токсичности метотрексата в связи со снижением его почечного клиренса на фоне терапии НПВП. Необходимо проводить подсчет клеток крови в начале одновременного применения. При наличии нарушения функции почек даже легкой степени, а также у лиц пожилого возраста, необходимо тщательное медицинское наблюдение.\u003Cbr\u003E\u003Cbr\u003EС пентоксифиллином: возможно повышение риска развития кровотечения. Необходим тщательный клинический мониторинг и регулярная проверка времени кровотечения (времени свертываемости крови).\u003Cbr\u003E\u003Cbr\u003EС зидовудином: существует риск усиления гокснческого действия на эритроциты, обусловленного воздействием на ретикулоциты, с развитием тяжелой анемии через неделю после начала применения НПВП. Необходимо проведение общего анализа крови с подсчетом количества ретикулоцитов через 1-2 недели после начала терапии НПВП.\u003Cbr\u003E\u003Cbr\u003EС пероральными гипогликемическими средствами: НПВП могут усиливать гипогликемическое действие препаратов сульфонилмочевины вследствие вытеснения ее из мест связывания с белками плазмы крови.\u003Cbr\u003E\u003Cbr\u003EКомбинации, которые необходимо принимать во внимание\u003Cbr\u003E\u003Cbr\u003EС бета-адреноблокапюрами: при одновременном применении с НПВП может уменьшаться антигипертензивный эффект бета-адреноблокаторов вследствие ингибирования синтеза простагландинов.\u003Cbr\u003E\u003Cbr\u003EС циклоспорином и такролифусом: НПВП могут увеличивать нефротоксичность, что опосредовано действием ренальных просгаглапдннов. Во время проведения одновременной терапии необходимо контролировать функцию почек.\u003Cbr\u003E\u003Cbr\u003EС тромболитиками: повышенный риск развития кровотечений.\u003Cbr\u003E\u003Cbr\u003EУвеличивается риск развития кровотечения из ЖКТ при одновременном применении с ингибиторами обратного захвата серотонина (циталопрам, флуоксетин, сертралин) и антикоагулянтами.\u003Cbr\u003E\u003Cbr\u003EС пробенецидом: возможно повышение концентрации НПВП в плазме крови, что может быть обусловлено ингибирующим эффектом пробенецида па почечную тубулярную секрецию и/или конъюгацию с глюкуроновой кислотой, что требует коррекции дозы НПВП.\u003Cbr\u003E\u003Cbr\u003EС сердечными гликозидами: одновременное применение с НПВП может приводить к повышению концентрации сердечных гликозидов в плазме крови.\u003Cbr\u003E\u003Cbr\u003EС мифепристоном: в связи с теоретическим риском изменения эффективности мифепристона под влиянием ингибиторов синтеза простагландинов, НПВП не следует назначать ранее, чем через 8-12 сут после отмены мифепристона.\u003Cbr\u003E\u003Cbr\u003EС хинолонами: данные, полученные в экспериментальных исследованиях на животных, указывают на высокий риск развития судорог при одновременном применении НПВП с хинолонами в высоких дозах.\u003Cbr\u003E\u003Cbr\u003EВ случае необходимости одновременного применения декскетонрофена с вышеперечисленными лекарственными средствами следует проконсультироваться с врачом.\u003Cbr\u003E"},{"name":"Регистрационный номер","value":"ЛП-006382"},{"name":"Дата государственной регистрации","value":"23.09.2020"},{"name":"Владелец регистрационного удостоверения","value":"Велфарм","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["34324371:35649313","7893318:16127911"]}}},{"name":"Изготовитель","value":"Велфарм"},{"name":"Фасовщик","value":"Велфарм"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Велдексал","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-travm-boli-v-myshtsakh-i-sustavakh","categoryId":"15756903","navnodeId":"25542230","glfilters":["17796364:20409632"]}}},{"name":"Срок годности","value":"36 мес."}]}},"fullSpecsGrouped":{"16005252797075663163":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Органы и системы","value":"нервная система, опорно-двигательная система"},{"name":"Назначение","value":"альгодисменорея, боль в мышцах, зубная боль"},{"name":"Показания к применению","value":"мышечно-скелетная боль (слабо или умеренно выраженная), альгодисменорея, зубная боль.\u003Cbr\u003E\u003Cbr\u003EПрепарат предназначен для симптоматического лечения, уменьшения боли и воспаления на момент применения.\u003Cbr\u003E"},{"name":"Противопоказания","value":"гиперчувствительность к декскетопрофену, другим компонентам препарата и другим НПВП;\u003Cbr\u003Eполное или неполное сочетание бронхиальной астмы, рецидивирующего полипоза носа и околоносовых пазух и непереносимости ацетилсалициловой кислоты или других НПВП (в том числе в анамнезе);\u003Cbr\u003Eэрозивно-язвенные поражения желудочно-кишечного тракта в стадии обострения;\u003Cbr\u003Eжелудочно-кишечные кровотечения или перфорации в анамнезе, включая связанные с предшествующим применением НПВП;\u003Cbr\u003Eжелудочно-кишечные кровотечения: другие активные кровотечения (в том числе подозрение на внутричерепное кровоизлияние);\u003Cbr\u003Eвоспалительные заболевания кишечника (болезнь Крона, язвенный колит) в стадии обострения;\u003Cbr\u003Eпеченочная недостаточность тяжелой степени тяжести (10-15 баллов по шкале Чайлд-Пью);\u003Cbr\u003Eпрогрессирующие заболевания почек, подтвержденная гиперкалиемия:\u003Cbr\u003Eхроническая болезнь почек: стадия 3а (скорость клубочковой фильтрации (СКФ) 45-59 мл/мин/1,73 м2), 3б (СКФ 30-44 мл/мин/1,73 м2) и 4 (СКФ \u003C30 мл/мин/1,73 м2);\u003Cbr\u003Eпериод после проведения аортокоронарного шунтирования:\u003Cbr\u003Eтяжелая сердечная недостаточность (III-IV класс по классификации NYHA);\u003Cbr\u003Eгеморрагический диатез и другие нарушения свертывания крови;\u003Cbr\u003Eвозраст до 18 лет (в связи с отсутствием данных по эффективности и безопасности);\u003Cbr\u003Eбеременность и период грудного вскармливания."},{"name":"Состав","value":"1 таблетка содержит:\u003Cbr\u003E\u003Cbr\u003EДействующее вещество: декскетопрофена трометамол - 36,9 мг (в пересчете на декскетопрофен — 25,0 мг).\u003Cbr\u003E\u003Cbr\u003EВспомогательные вещества; целлюлоза микрокристаллическая МС-101, крахмал кукурузный, крахмал кукурузный прежелатинизированный, гипролоза (гидроксипропилцеллюлоза), магния стеарат.\u003Cbr\u003E\u003Cbr\u003EСостав оболочки: [сухая смесь для пленочного покрытия, содержащая гипромеллозу, титана диоксид, макрогол 6000 (Опадрай 03F180011 белый) или гипромеллоза (оксипропилметилцеллюлоза), титана диоксид, макрогол 6000 (полиэтиленгликоль 6000, полиэтиленоксид 6000)].\u003Cbr\u003E"},{"name":"Действующее вещество","value":"Декскетопрофен"},{"name":"Способ применения и дозы","value":"Декскетопрофен принимают внутрь во время еды. Одновременный прием пищи замедляет всасывание декскетопрофена, поэтому в случае острой боли рекомендуется применение препарата не менее чем за 30 мин до приема пищи.\u003Cbr\u003E\u003Cbr\u003EДля обеспечения указанных ниже режимов дозирования при необходимости применения дозы 12.5 мг. в том числе у пациентов особых групп, следует использовать препарат декскетопрофена других производителей с возможностью соответствующего режима дозирования с применением минимальной дозы (с риской).\u003Cbr\u003E\u003Cbr\u003EВ зависимости от интенсивности болевого синдрома рекомендуемая доза для взрослых составляет 12,5 мг декскетопрофена (1/2 таблетки) каждые 4-6 часов или 25 мг декскетопрофена (1 таблетка) каждые 8 ч.\u003Cbr\u003E\u003Cbr\u003EМаксимальная суточная доза - 75 мг.\u003Cbr\u003E\u003Cbr\u003EДекскетопрофен не предназначен для длительной терапии, курс лечения препаратом не должен превышать 3-5 дней.\u003Cbr\u003E\u003Cbr\u003EПациенты 65 лет и старше\u003Cbr\u003E\u003Cbr\u003EПациентам пожилого возраста следует принимать препарат, начиная с минимальной рекомендованной дозы.\u003Cbr\u003E\u003Cbr\u003EМаксимальная суточная доза составляет 50 мг.\u003Cbr\u003E\u003Cbr\u003EВ случае хорошей переносимости могут применяться дозы, рекомендованные для общей популяции.\u003Cbr\u003E\u003Cbr\u003EПациенты с печеночной недостаточностью\u003Cbr\u003E\u003Cbr\u003EПациентам с печеночной недостаточностью легкой и средней степени тяжести следует принимать препарат, начиная с минимальной рекомендованной дозы.\u003Cbr\u003E\u003Cbr\u003EМаксимальная суточная доза составляет 50 мг.\u003Cbr\u003E\u003Cbr\u003EПрименение декскетопрофена у пациентов с печеночной недостаточностью тяжелой степени тяжести противопоказано.\u003Cbr\u003E\u003Cbr\u003EПациенты с почечной недостаточностью\u003Cbr\u003E\u003Cbr\u003EПациентам с почечной недостаточностью легкой степени тяжести - хроническая болезнь почек, стадия 2 (СКФ 60-89 мл/мин/1,73 м2) следует принимать декскетопрофен. начиная с минимальной рекомендованной дозы.\u003Cbr\u003E\u003Cbr\u003EМаксимальная суточная доза составляет 50 мг.\u003Cbr\u003E\u003Cbr\u003EПрименение декскетопрофена у пациентов с хронической болезнью почек стадий 3а (СКФ 45-59 мл/мин/1,73 м2), 3б (СКФ 30-44 мл/мин/1,73 м2) и 4 (СКФ \u003C30 мл/мин/1,73 м2) противопоказано.\u003Cbr\u003E"},{"name":"Побочные действия","value":"Возможные побочные эффекты приведены в соответствии с классификацией Всемирной организации здравоохранения ниже по убыванию частоты возникновения: очень часто (≥1/10), часто (≥1/100 и \u003C1/10). нечасто (≥1/1000 и \u003C1/100). редко (≥1/10000 и \u003C1/1000). очень редко (\u003C1/10000). включая отдельные сообщения.\u003Cbr\u003E\u003Cbr\u003EНарушения со стороны крови и лимфатической системы: очень редко - нейтропения, тромбоцитопения.\u003Cbr\u003E\u003Cbr\u003EНарушения со стороны иммунной системы: редко — отек гортани; очень редко — анафилактические реакции, включая анафилактический шок.\u003Cbr\u003E\u003Cbr\u003EНарушения со стороны обмена веществ и питания: редко - анорексия.\u003Cbr\u003E\u003Cbr\u003EНарушения психики: нечасто — бессонница, ощущение беспокойства.\u003Cbr\u003E\u003Cbr\u003EНарушения со стороны нервной системы: нечасто - головная боль, головокружение, сонливость; редко — парестезии, синкопальные состояния (преходящие кратковременные обмороки).\u003Cbr\u003E\u003Cbr\u003EНарушения со стороны органа зрения: очень редко - нечеткость зрения.\u003Cbr\u003E\u003Cbr\u003EНарушения со стороны органа слуха и лабиринтные нарушения: нечасто - вертиго; очень редко - шум в ушах.\u003Cbr\u003E\u003Cbr\u003EНарушения со стороны сердца: нечасто - ощущение сердцебиения, чувство жара, гиперемия кожных покровов; редко - повышение артериального давления; очень редко - тахикардия, снижение артериального давления.\u003Cbr\u003E\u003Cbr\u003EНарушения со стороны дыхательной системы, органов грудной клетки и средостения: редко - брадипноэ; очень редко - бронхоспазм, одышка.\u003Cbr\u003E\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта: часто - тошнота, рвота, боль в животе, диспепсия, диарея; нечасто - гастрит, запор, сухость во рту, метеоризм; редко - эрозивно-язвенные поражения желудочно-кишечного тракта (ЖКТ), кровотечение из язвы или ее перфорация; очень редко - поражение поджелудочной железы.\u003Cbr\u003E\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей: редко - гепатит, повышение активности «печеночных» ферментов, в том числе аспартатаминотрансферазы и аланинаминотрансферазы (ACT и АЛТ): очень редко - поражение печени.\u003Cbr\u003E\u003Cbr\u003EНарушения со стороны кожу и подкожных тканей: нечасто - кожная сыпь; редко — крапивница, угревая сыпь, потливость; очень редко - тяжелые кожные реакции (синдром Стивенса-Джонсона, токсический эпидермальный некролиз (синдром Лайелла)), ангионевротический отек, отек лица, аллергический дерматит, фотосенсибилизация, кожный зуд.\u003Cbr\u003E\u003Cbr\u003EНарушения со стороны скелетно-мышечной и соединительной ткани: редко - боль в спине.\u003Cbr\u003E\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей: редко - полиурия, острая почечная недостаточность; очень редко - нефрит или нефротический синдром.\u003Cbr\u003E\u003Cbr\u003EНарушения со стороны половых органов и молочной железы: редко — у женщин — нарушение менструального цикла, у мужчин - преходящее нарушение функции предстательной железы при длительном примеиенип.\u003Cbr\u003E\u003Cbr\u003EОбщие расстройства и нарушения, в месте введения: нечасто - повышенная утомляемость, астения, озноб, общее недомогание; очень редко - периферические отеки.\u003Cbr\u003E\u003Cbr\u003EКак и при применении других НПВП, возможно развитие следующих побочных эффектов: асептический менингит, возникающий преимущественно у пациентов с системной красной волчанкой или другими системными заболеваниями соединительной ткани, гематологические нарушения (тромбоцитопеническая пурпура, апластическая и гемолитическая анемии), редко - агранулоцитоз и гипоплазия костного мозга.\u003Cbr\u003E"},{"name":"Фармакологическое действие","value":"Декскетопрофена трометамол относится к нестероидным противовоспалительным препаратам (НПВП), оказывает обезболивающее, противовоспалительное и жаропонижающее действие. Механизм действия декскетопрофена основан па ингибировании синтеза простагландинов на уровне циклооксигеназ (ЦОГ-1 и ЦОГ-2).\u003Cbr\u003E\u003Cbr\u003EОбезболивающий эффект наступает через 30 мин после приема препарата внутрь, продолжительность терапевтического действия составляет 4-6 ч.\u003Cbr\u003E"},{"name":"Фармакологическая группа","value":"нестероидный противовоспалительный препарат (НПВП)"},{"name":"Форма выпуска","value":"таблетки, покрытые пленочной оболочкой"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 18 лет"},{"name":"Продолжительность действия","value":"4-6 часов"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"При температуре не выше 25 °C.\u003Cbr\u003E\u003Cbr\u003EХранить в недоступном для детей месте.\u003Cbr\u003E"},{"name":"Передозировка","value":"Симптомы: тошнота, анорексия, боль в животе, головная боль, головокружение, дезориентация, бессонница.\u003Cbr\u003E\u003Cbr\u003EЛечение: симптоматическая терапия, при необходимости - промывание желудка, прием активированного угля; гемодиализ малоэффективен.\u003Cbr\u003E"},{"name":"Применение при беременности и кормлении грудью","value":"Применение декскетопрофена при беременности и в период грудного вскармливания противопоказано."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"В связи с возможным головокружением и сонливостью в период приема декскетопрофена, способность к концентрации внимания и быстрота психомоторных реакций у пациентов могут снижаться, особенно в первый час после приема препарата. Поэтому в период лечения декскетопрофеном следует соблюдать осторожность при управлении транспортными средствами и занятиях потенциально опасными вилами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"Нежелательные побочные эффекты можно свести к минимуму при применении препарата в наименьшей эффективной дозе при минимальной длительности применения, необходимой для купирования болевого синдрома.\u003Cbr\u003E\u003Cbr\u003EРиск возникновения осложнений со стороны ЖКТ повышается у пациентов с язвенным поражением ЖКТ в анамнезе, у пожилых пациентов, при увеличении дозы НПВП; поэтому применение декскетонрофена у этой категории пациентов следует начинать с наименьшей рекомендуемой дозы.\u003Cbr\u003E\u003Cbr\u003EПациентам вышеперечисленных категорий, а также пациентам, которым требуется одновременное применение низких доз ацетилсалициловой кислоты или других средств, повышающих риск возникновения осложнений со стороны ЖКТ, рекомендуется дополнительно одновременное применение гастропротекторов (мизопростол или блокаторы протонной помпы).\u003Cbr\u003E\u003Cbr\u003EУ пациентов, одновременно принимающих антиагреганты или антикоагулянты, глюкокортикостероиды, также повышается риск возникновения желудочно-кишечного кровотечения.\u003Cbr\u003E\u003Cbr\u003EПациенты с нарушениями со стороны желудочно-кишечного тракта или желудочно-кишечными заболеваниями в анамнезе должны находиться под тщательным медицинским наблюдением. В случае возникновения желудочно-кишечного кровотечения или язвенного поражения терапию декскетопрофеном следует отменить.\u003Cbr\u003E\u003Cbr\u003EДекскетопрофен следует применять с осторожностью у пациентов с желудочно-кишечными заболеваниями в анамнезе (язвенный колит, болезнь Крона), поскольку возможно обострение этих заболеваний.\u003Cbr\u003E\u003Cbr\u003EВсе НПВП могут ингибировать агрегацию тромбоцитов и увеличивать время кровотечения за счет ингибирования синтеза простагландинов. В связи с этим применение декскетопрофена у пациентов, одновременно принимающих препараты, влияющие на систему гемостаза, такие как варфарин, производные кумарина и гепарины, не рекомендовано.\u003Cbr\u003E\u003Cbr\u003EКак и другие НПВП, декскетопрофен может приводить к повышению концентрации креатинина и азота в плазме крови. Как и другие ингибиторы синтеза простагландинов, декскетопрофен может оказывать побочное действие на мочевыделительную систему, что может привести к развитию гломерулонефрита, интерстициального нефрита, папиллярного некроза, нефротического синдрома и острой почечной недостаточности. Следует соблюдать осторожность при применении препарата у пациентов, одновременно применяющих диуретики и пациентов, у которых возможно развитие гиповолемии, в связи с повышенным риском нефротоксичности.\u003Cbr\u003E\u003Cbr\u003EКак и при применении других НПВП. па фоне терапии текскетопрофеном может наблюдаться небольшое преходящее повышение активности «печеночных» ферментов. У пациентов пожилого возраста необходим контроль функции печени и почек. В случае значительного повышения соответствующих показателей декскетопрофен следует отменить.\u003Cbr\u003E\u003Cbr\u003EКак и другие НПВП, декскетопрофен может маскировать симптомы инфекционных заболеваний. В случае обнаружения признаков инфекции или ухудшения самочувствия на фоне терапии декскетопрофеном пациенту необходимо сразу обратиться к врачу.\u003Cbr\u003E\u003Cbr\u003EПрепарат может вызывать задержку жидкости в организме, поэтому у пациентов с артериальной гипертензией, с почечной и/или сердечной недостаточностью декскетопрофен следует применять с особой осторожностью. В случае ухудшения состояния применение препарата необходимо прекратить.\u003Cbr\u003E\u003Cbr\u003EУ пациентов с неконтролируемой артериальной гипертензией. ишемической болезнью сердца, застойной сердечной недостаточностью, заболеваниями периферических артерий и/или цереброваскулярными заболеваниями препарат следует применять с осторожностью. Аналогичный подход применим к пациентам с факторами риска развития сердечно-сосудистых заболеваний (артериальная гипертензия, гиперлипидемия, сахарный диабет, курение).\u003Cbr\u003E\u003Cbr\u003EНеобходимо соблюдать осторожность при назначении декскетонрофена пациентам с наличием в анамнезе сердечно-сосудистых заболеваний, особенно пациентам с сердечной недостаточностью, в связи с возможным риском прогрессирования.\u003Cbr\u003E\u003Cbr\u003EКлинические исследования и эпидемиологические данные позволяют сделать вывод о том, что НПВП, особенно в высоких дозах и при длительном применении, могут приводить к незначительному риску развития острого инфаркта миокарда или инсульта. Для исключения риска данных событий при применении декскетопрофена данных недостаточно.\u003Cbr\u003E\u003Cbr\u003EПожилые пациенты особенно подвержены неблагоприятным реакциям при применении НПВП, в том числе, риску возникновения желудочно-кишечных кровотечений и перфораций, угрожающим жизни пациента, снижению функций почек, печени и сердца. При применении декскетопрофена у данной категории пациентов необходим надлежащий клинический контроль.\u003Cbr\u003E\u003Cbr\u003EИмеются данные о возникновении редких случаев кожных реакций (таких как эксфолиативный дерматит, синдром Стивенса-Джонсона, токсический эпидермальный некролиз) при применении НПВП. При первых проявлениях кожной сыпи, поражении слизистых оболочек или других признаках аллергической реакции прием декскетопрофена следует немедленно прекратить и обратиться к врачу.\u003Cbr\u003E\u003Cbr\u003EС осторожностью:\u003Cbr\u003EЯзвенная болезнь желудка и двенадцатиперстной кишки, язвенный колит, болезнь Крона, заболевания печени в анамнезе, печеночная порфирия, хроническая болезнь почек, стадия 2 (СКФ 60-89 мл/мин/1,73 м2), хроническая сердечная недостаточность, артериальная гипертензия, значительное снижение объема циркулирующей крови (в том числе после хирургического вмешательства), пожилые пациенты старше 65 лет (в том числе получающие диуретики, ослабленные пациенты и пациенты с низкой массой тела), бронхиальная астма, одновременный прием глюкокортикостероидов (в том числе преднизолона), антикоагулянтов (в том числе варфарина), антиагрегантов (в том числе ацетилсалициловой кислоты, клопидогрела), селективных ингибиторов обратного захвата серотонина (в том числе циталопрама, флуоксетина, пароксетина, сертралина), ишемическая болезнь сердца. цереброваскулярные заболевания, дислипидемия/гиперлипидемия, сахарный диабет, заболевания периферических артерий, курение, наличие инфекции Helicobacter pylori, системная красная волчанка (СКВ) и другие системные заболевания соединительной ткани, длительное применение НПВП, туберкулез, выраженный остеопороз, алкоголизм, тяжелые соматические заболевания.\u003Cbr\u003E"},{"name":"Взаимодействие","value":"Нижеследующие взаимодействия характерны для всех НПВП.\u003Cbr\u003E\u003Cbr\u003EНежелательные комбинации\u003Cbr\u003E\u003Cbr\u003EС другими НПВП, включая салицилаты в высоких дозах (более 3г в сутки): одновременное применение нескольких НПВП вследствие синергического эффекта повышает риск развития желудочно-кишечного кровотечения и язвы.\u003Cbr\u003E\u003Cbr\u003EС антикоагулянтами: декскетопрофен, как и другие НПВП, может усиливать эффект антикоагулянтов, таких как варфарин в связи с высокой степенью связывания с белками плазмы крови, ингибированием агрегации тромбоцитов и поражением слизистой оболочки желудочно-кишечного тракта. В случае необходимости одновременного применения необходим тщательный контроль за состоянием пациента и регулярный мониторинг лабораторных показателей.\u003Cbr\u003E\u003Cbr\u003EС гепарином: при одновременном применении повышается риск развития кровотечения (в связи с ингибированием агрегации тромбоцитов и повреждающим действием на слизистую оболочку желудочно-кишечного тракта). В случае необходимости одновременного применения необходим тщательный контроль за состоянием пациента и регулярный мониторинг лабораторных показателей.\u003Cbr\u003E\u003Cbr\u003EС глюкокортикостероидами: при одновременном применении повышается риск язвенного поражения желудочно-кишечного тракта и кровотечений.\u003Cbr\u003E\u003Cbr\u003EС препаратами лития: НПВП повышают концентрацию лития в плазме крови вплоть до токсической в связи с чем, данный показатель необходимо контролировать при одновременном применении с декскетопрофспом, изменении дозировки, а также после отмены НПВП.\u003Cbr\u003E\u003Cbr\u003EС метотрексатом в высоких дозах (15 мг в неделю и более): возможно повышение гематологической токсичности метотрексата в связи со снижением его почечного клиренса при одновременном применении с НПВП.\u003Cbr\u003E\u003Cbr\u003EС гидантоинами и сульфонамидами: возможно усиление их токсического действия.\u003Cbr\u003E\u003Cbr\u003EКомбинации, требующие осторожности\u003Cbr\u003E\u003Cbr\u003EС диуретиками, ингибиторами ангиотензинпреврсицающего фермента (АПФ), антибиотиками из группы аминогликозидов, антагонистами рецепторов апгиотензина-II: одновременное применение с НПВП связано с риском развития острой почечной недостаточности у обезвоженных пациентов (снижение клубочковой фильтрации, обусловленное сниженным синтезом простагландинов). При одновременном применении НПВП могут уменьшать антигипертензивный эффект некоторых препаратов. При одновременном применении декскетопрофена и диуретиков необходимо убедиться, что у пациента отсутствуют признаки обезвоживания, а также в начале одновременного применения контролировать функцию почек.\u003Cbr\u003E\u003Cbr\u003EС метотрексатом в низких дозах (менее 15 мг в неделю): возможно повышение гематологической токсичности метотрексата в связи со снижением его почечного клиренса на фоне терапии НПВП. Необходимо проводить подсчет клеток крови в начале одновременного применения. При наличии нарушения функции почек даже легкой степени, а также у лиц пожилого возраста, необходимо тщательное медицинское наблюдение.\u003Cbr\u003E\u003Cbr\u003EС пентоксифиллином: возможно повышение риска развития кровотечения. Необходим тщательный клинический мониторинг и регулярная проверка времени кровотечения (времени свертываемости крови).\u003Cbr\u003E\u003Cbr\u003EС зидовудином: существует риск усиления гокснческого действия на эритроциты, обусловленного воздействием на ретикулоциты, с развитием тяжелой анемии через неделю после начала применения НПВП. Необходимо проведение общего анализа крови с подсчетом количества ретикулоцитов через 1-2 недели после начала терапии НПВП.\u003Cbr\u003E\u003Cbr\u003EС пероральными гипогликемическими средствами: НПВП могут усиливать гипогликемическое действие препаратов сульфонилмочевины вследствие вытеснения ее из мест связывания с белками плазмы крови.\u003Cbr\u003E\u003Cbr\u003EКомбинации, которые необходимо принимать во внимание\u003Cbr\u003E\u003Cbr\u003EС бета-адреноблокапюрами: при одновременном применении с НПВП может уменьшаться антигипертензивный эффект бета-адреноблокаторов вследствие ингибирования синтеза простагландинов.\u003Cbr\u003E\u003Cbr\u003EС циклоспорином и такролифусом: НПВП могут увеличивать нефротоксичность, что опосредовано действием ренальных просгаглапдннов. Во время проведения одновременной терапии необходимо контролировать функцию почек.\u003Cbr\u003E\u003Cbr\u003EС тромболитиками: повышенный риск развития кровотечений.\u003Cbr\u003E\u003Cbr\u003EУвеличивается риск развития кровотечения из ЖКТ при одновременном применении с ингибиторами обратного захвата серотонина (циталопрам, флуоксетин, сертралин) и антикоагулянтами.\u003Cbr\u003E\u003Cbr\u003EС пробенецидом: возможно повышение концентрации НПВП в плазме крови, что может быть обусловлено ингибирующим эффектом пробенецида па почечную тубулярную секрецию и/или конъюгацию с глюкуроновой кислотой, что требует коррекции дозы НПВП.\u003Cbr\u003E\u003Cbr\u003EС сердечными гликозидами: одновременное применение с НПВП может приводить к повышению концентрации сердечных гликозидов в плазме крови.\u003Cbr\u003E\u003Cbr\u003EС мифепристоном: в связи с теоретическим риском изменения эффективности мифепристона под влиянием ингибиторов синтеза простагландинов, НПВП не следует назначать ранее, чем через 8-12 сут после отмены мифепристона.\u003Cbr\u003E\u003Cbr\u003EС хинолонами: данные, полученные в экспериментальных исследованиях на животных, указывают на высокий риск развития судорог при одновременном применении НПВП с хинолонами в высоких дозах.\u003Cbr\u003E\u003Cbr\u003EВ случае необходимости одновременного применения декскетонрофена с вышеперечисленными лекарственными средствами следует проконсультироваться с врачом.\u003Cbr\u003E"},{"name":"Регистрационный номер","value":"ЛП-006382"},{"name":"Дата государственной регистрации","value":"23.09.2020"},{"name":"Владелец регистрационного удостоверения","value":"Велфарм"},{"name":"Изготовитель","value":"Велфарм"},{"name":"Фасовщик","value":"Велфарм"},{"name":"Страна бренда","value":"Россия"},{"name":"Страна-производитель","value":"Россия"},{"name":"Название препарата","value":"Велдексал"},{"name":"Срок годности","value":"36 мес."}]}],"transitionId":"tr_7181820755913837944"}}}}
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Ещё может подойти

  • Артроцин капс., 36 шт., 1 уп.
    –42 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-5pcueelh1x7/toggleWishlist":{"skuId":"227812021","productId":1422663457,"offerId":"Qv3TiIDGyhw5cCV33kNcCA","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQkfGNsOmRlPBfEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhUIob6wpgUQtcXQbBjY+tQHIOfcwQc=","sign":"JNjA1sEcUlsNqZG//C7igSlOB+pC5oblwJRklmpKb6g="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-5pcueelh1x7/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Артроцин капс., 36 шт., 1 уп.

    Рейтинг товара: 4.6 из 5
    на основе 39 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 497 ₽ вместо 507
    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капс., 36 шт., 1 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  • Артнео капс., 35 г, 30 шт., нейтральный, 1 уп.
    –68 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-smcq6wv2m3h/toggleWishlist":{"skuId":"925352018","productId":1778175351,"offerId":"Dtww0LlWKdfSHVTt2bhjqg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQkfGNsOmRlPBfEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhYI95rzzwYQ0oCfuQMYn+ajByDn3MEH","sign":"wG6AXfzgf1Y4I5Ixb2DGPLN5ngYNnmcDFuS5izeb4ek="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-smcq6wv2m3h/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Артнео капс., 35 г, 30 шт., нейтральный, 1 уп.

    Рейтинг товара: 4.8 из 5
    на основе 311 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 1 362 ₽ вместо 1 390
    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  • Лошадиная сила бальзам-гель Релаксирующий, 125 мл, 125 г, 1 шт., ментол, 1 уп.
    –40 %
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    Лошадиная сила бальзам-гель Релаксирующий, 125 мл, 125 г, 1 шт., ментол, 1 уп.

    Рейтинг товара: 4.8 из 5
    на основе 268 оценок
    Цена 470 ₽ вместо 780
    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  • Волкизи таб. п/о плен., 30 шт.
    –27 %
    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-023mkbrivxr7/toggleWishlist":{"skuId":"101552487152","productId":1496886454,"offerId":"X-thTZsGnAuVyk3URyUQ4g","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQkfGNsOmRlPBfEjEKL0NvbXBldGl0aXZlQW5hbG9nc19NYXJrZXRNb2RlbENhcmRfRnJvbnRTbmlwcGV0MhcIttniyQUQ8PX/p/oCGMji0Acg59zBBw==","sign":"Ko3ubvcxTw8GsjLj5NFOi6JI4yxo3QfnlTv7z6IRrU4="},"waitWishlistCollections":false,"place":{"page":"product","widget":"scrollbox"}}}},"meta":{"/content/page/fancyPage/kkmCarousel/kkmCarousel/content/content/slot-023mkbrivxr7/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Волкизи таб. п/о плен., 30 шт.

    Рейтинг товара: 5 из 5
    на основе 4 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 932 ₽ вместо 950
    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  • Артрофорс спрей, 50 мл, 50 г, 1 шт., 3 х 8 см, 1 уп.
    –64 %
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    Артрофорс спрей, 50 мл, 50 г, 1 шт., 3 х 8 см, 1 уп.

    Рейтинг товара: 4.3 из 5
    на основе 85 оценок
    Цена 304 ₽ вместо 840
    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  • Фулфлекс капс., 0.3 г, 24 шт., 1 уп.
    –27 %
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    Фулфлекс капс., 0.3 г, 24 шт., 1 уп.

    Рейтинг товара: 4.8 из 5
    на основе 39 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 410 ₽ вместо 414
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  • Артра МСМ таб. п/о плён., 101.4 г, 60 шт., 1 уп.
    –1 %
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    Артра МСМ таб. п/о плён., 101.4 г, 60 шт., 1 уп.

    Рейтинг товара: 4.8 из 5
    на основе 1122 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 2 657 ₽ вместо 2 684
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  • Ревмафлекс капс., 60 шт., нейтральный, 1 уп.
    –1 %
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    Ревмафлекс капс., 60 шт., нейтральный, 1 уп.

    Рейтинг товара: 4.5 из 5
    на основе 14 оценок
    С картой  Пэй
    Цена с картой Яндекс Пэй 948 ₽ вместо 958
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  • Протекта таб. шип., 20 шт., нейтральный
    –35 %
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    Протекта таб. шип., 20 шт., нейтральный

    Рейтинг товара: 4.8 из 5
    на основе 52 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 1 670 ₽ вместо 1 687
    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  • Артроцин форте капс., 36 шт., 1 уп.
    –1 %
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    Артроцин форте капс., 36 шт., 1 уп.

    Рейтинг товара: 5 из 5
    на основе 2 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 396 ₽ вместо 400
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  • Хонда Нейро таб., 20 шт., нейтральный
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    Хонда Нейро таб., 20 шт., нейтральный

    Рейтинг товара: 4.6 из 5
    на основе 221 оценка
    Цена 810 ₽
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  • Локоген таб., 30 шт.
    –1 %
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    Локоген таб., 30 шт.

    Рейтинг товара: 5 из 5
    на основе 3 оценки
    С картой  Пэй
    Цена с картой Яндекс Пэй 2 534 ₽ вместо 2 560
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Инструкция

Показания к применению

мышечно-скелетная боль (слабо или умеренно выраженная), альгодисменорея, зубная боль.

Препарат предназначен для симптоматического лечения, уменьшения боли и воспаления на момент применения.

Противопоказания

гиперчувствительность к декскетопрофену, другим компонентам препарата и другим НПВП;
полное или неполное сочетание бронхиальной астмы, рецидивирующего полипоза носа и околоносовых пазух и непереносимости ацетилсалициловой кислоты или других НПВП (в том числе в анамнезе);
эрозивно-язвенные поражения желудочно-кишечного тракта в стадии обострения;
желудочно-кишечные кровотечения или перфорации в анамнезе, включая связанные с предшествующим применением НПВП;
желудочно-кишечные кровотечения: другие активные кровотечения (в том числе подозрение на внутричерепное кровоизлияние);
воспалительные заболевания кишечника (болезнь Крона, язвенный колит) в стадии обострения;
печеночная недостаточность тяжелой степени тяжести (10-15 баллов по шкале Чайлд-Пью);
прогрессирующие заболевания почек, подтвержденная гиперкалиемия:
хроническая болезнь почек: стадия 3а (скорость клубочковой фильтрации (СКФ) 45-59 мл/мин/1,73 м2), 3б (СКФ 30-44 мл/мин/1,73 м2) и 4 (СКФ <30 мл/мин/1,73 м2);
период после проведения аортокоронарного шунтирования:
тяжелая сердечная недостаточность (III-IV класс по классификации NYHA);
геморрагический диатез и другие нарушения свертывания крови;
возраст до 18 лет (в связи с отсутствием данных по эффективности и безопасности);
беременность и период грудного вскармливания.

Способ применения и дозы

Декскетопрофен принимают внутрь во время еды. Одновременный прием пищи замедляет всасывание декскетопрофена, поэтому в случае острой боли рекомендуется применение препарата не менее чем за 30 мин до приема пищи.

Для обеспечения указанных ниже режимов дозирования при необходимости применения дозы 12.5 мг. в том числе у пациентов особых групп, следует использовать препарат декскетопрофена других производителей с возможностью соответствующего режима дозирования с применением минимальной дозы (с риской).

В зависимости от интенсивности болевого синдрома рекомендуемая доза для взрослых составляет 12,5 мг декскетопрофена (1/2 таблетки) каждые 4-6 часов или 25 мг декскетопрофена (1 таблетка) каждые 8 ч.

Максимальная суточная доза - 75 мг.

Декскетопрофен не предназначен для длительной терапии, курс лечения препаратом не должен превышать 3-5 дней.

Пациенты 65 лет и старше

Пациентам пожилого возраста следует принимать препарат, начиная с минимальной рекомендованной дозы.

Максимальная суточная доза составляет 50 мг.

В случае хорошей переносимости могут применяться дозы, рекомендованные для общей популяции.

Пациенты с печеночной недостаточностью

Пациентам с печеночной недостаточностью легкой и средней степени тяжести следует принимать препарат, начиная с минимальной рекомендованной дозы.

Максимальная суточная доза составляет 50 мг.

Применение декскетопрофена у пациентов с печеночной недостаточностью тяжелой степени тяжести противопоказано.

Пациенты с почечной недостаточностью

Пациентам с почечной недостаточностью легкой степени тяжести - хроническая болезнь почек, стадия 2 (СКФ 60-89 мл/мин/1,73 м2) следует принимать декскетопрофен. начиная с минимальной рекомендованной дозы.

Максимальная суточная доза составляет 50 мг.

Применение декскетопрофена у пациентов с хронической болезнью почек стадий 3а (СКФ 45-59 мл/мин/1,73 м2), 3б (СКФ 30-44 мл/мин/1,73 м2) и 4 (СКФ <30 мл/мин/1,73 м2) противопоказано.
Полная инструкция
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Велдексал таб. п/o плен.
Велдексал таб. п/o плен., 25 мг, 10 шт.
5.0
(8)
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Инструкция

Цена с картой Яндекс Пэй:427 ₽

Скидка: 2%
–2 %
Вместо: 435 ₽
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5.0
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У продавца:8 оценок·3 отзыва
У всех продавцов:12 оценок·3 отзыва
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user avatar
6 дней назад • Иван Тяпкин • Куплен на Маркете
Достоинства: Помогает
Недостатки: Нет
Комментарий: Все ожидания опровдали
user avatar
8 месяцев назад • Александр Никитин • Куплен на Маркете
Достоинства: Нормально, как дексалгин
user avatar
11 месяцев назад • Бибигуль Удербаева • Куплен на Маркете
Недостатки: нет
Комментарий: помогло
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Рекомендуем

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    Таблетница на день мини для капсул контейнер для таблеток белый

    Цена 282 ₽ вместо 750
  • Таблетница - брелок на день, 1 раздел, контейнер для таблеток металлический маленький (черный матовый)
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    Таблетница - брелок на день, 1 раздел, контейнер для таблеток металлический маленький (черный матовый)

    Цена 209 ₽ вместо 599
  • Волкизи таб. п/о плен., 30 шт.
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    Волкизи таб. п/о плен., 30 шт.

    Цена 932 ₽ вместо 1 280
  • Таблетница компактная /органайзер аптечка/ контейнер для таблеток БАД Panda_Home (синего цвета)
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    Таблетница компактная /органайзер аптечка/ контейнер для таблеток БАД Panda_Home (синего цвета)

    Цена 245 ₽ вместо 263
  • Фулфлекс капс., 0.3 г, 24 шт., 1 уп.
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    Фулфлекс капс., 0.3 г, 24 шт., 1 уп.

    Цена 410 ₽ вместо 564
  • Таблетница, органайзер на день, неделю, контейнер для таблеток, лекарств и витамин
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    Таблетница, органайзер на день, неделю, контейнер для таблеток, лекарств и витамин

    Цена 149 ₽ вместо 470
  • Артра МСМ таб. п/о плён., 101.4 г, 60 шт., 1 уп.
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    Артра МСМ таб. п/о плён., 101.4 г, 60 шт., 1 уп.

    Цена 2 657 ₽ вместо 2 684
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    Реклама
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  • Артроцин капс., 36 шт., 1 уп.
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    Артроцин капс., 36 шт., 1 уп.

    Цена 497 ₽ вместо 853
  • Ревмафлекс капс., 60 шт., нейтральный, 1 уп.
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778175162_10/content/content/gallery":{"title":"Ревмафлекс капс., 60 шт., нейтральный, 1 уп.","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/5235182/img_id7240902984627641170.jpeg/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/5235182/img_id7240902984627641170.jpeg/120x160 120w, https://avatars.mds.yandex.net/get-mpic/5235182/img_id7240902984627641170.jpeg/180x240 180w, https://avatars.mds.yandex.net/get-mpic/5235182/img_id7240902984627641170.jpeg/240x320 240w, https://avatars.mds.yandex.net/get-mpic/5235182/img_id7240902984627641170.jpeg/300x400 300w, https://avatars.mds.yandex.net/get-mpic/5235182/img_id7240902984627641170.jpeg/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"},{"src":"https://avatars.mds.yandex.net/get-mpic/1927422/img_id7935672565540282125.png/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/1927422/img_id7935672565540282125.png/120x160 120w, https://avatars.mds.yandex.net/get-mpic/1927422/img_id7935672565540282125.png/180x240 180w, https://avatars.mds.yandex.net/get-mpic/1927422/img_id7935672565540282125.png/240x320 240w, https://avatars.mds.yandex.net/get-mpic/1927422/img_id7935672565540282125.png/300x400 300w, https://avatars.mds.yandex.net/get-mpic/1927422/img_id7935672565540282125.png/600x800 600w","sizes":"(max-width: 1456px) 15vw, 217px"}],"firstImageLazyLoading":false,"baobabClientData":{"realTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQkfGNsOmRlPBfEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIWCLqZ888GELmypb4CGNW7oQYg59zBBw==","sign":"pwSbsrpYEF/zzlxaCz9w0l1Eti0MDgjr6VyKUDQCkKI="},"target":"model_card"},"isNoPicturePadding":true}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1778175162_10/content/content/gallery":{"name":"@marketfront/SnippetConstructor/Gallery"}}}
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    Ревмафлекс капс., 60 шт., нейтральный, 1 уп.

    Цена 948 ₽ вместо 958
  • Лошадиная сила бальзам-гель Релаксирующий, 125 мл, 125 г, 1 шт., ментол, 1 уп.
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    Лошадиная сила бальзам-гель Релаксирующий, 125 мл, 125 г, 1 шт., ментол, 1 уп.

    Цена 470 ₽ вместо 780
  • Таблетница органайзер на неделю утро / день / вечер; Органайзер для таблеток на 7 дней; Карманная аптечка
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    Таблетница органайзер на неделю утро / день / вечер; Органайзер для таблеток на 7 дней; Карманная аптечка

    Цена 773 ₽ вместо 1 890
  • Артрофорс спрей, 50 мл, 50 г, 1 шт., 3 х 8 см, 1 уп.
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    Артрофорс спрей, 50 мл, 50 г, 1 шт., 3 х 8 см, 1 уп.

    Цена 304 ₽ вместо 840
  • Протекта таб. шип., 20 шт., нейтральный
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    Протекта таб. шип., 20 шт., нейтральный

    Цена 1 670 ₽ вместо 2 583
  • Артроцин форте капс., 36 шт., 1 уп.
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    {"widgets":{"@marketfront/SnippetConstructor/ToggleWishlist":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1780858069_15/content/content/toggleWishlist":{"skuId":"228004039","productId":1780858069,"offerId":"forUG4N5-X1dT4GoT03_eg","size":24,"color":"#BDBDBC","wishlistLink":"/my/wishlist","baobabRealTimeEventPayload":{"version":"EPV_BRT_V1","payload":"CgoQkfGNsOmRlPBfEhoKGHJlbWl4X2Rlc2t0b3BfbW9kZWxfY2FyZDIVCNX5ltEGEMeh3GwY2PrUByDn3MEH","sign":"Agw50o8VApFWVL8FSi/yQ1y4noA5Egcm9bYC9UNVvDE="},"waitWishlistCollections":false,"place":{"page":"product","widget":"feed"}}}},"meta":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1780858069_15/content/content/toggleWishlist":{"name":"@marketfront/SnippetConstructor/ToggleWishlist"}}}

    Артроцин форте капс., 36 шт., 1 уп.

    Цена 396 ₽ вместо 400
  • Хонда Нейро таб., 20 шт., нейтральный
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    Хонда Нейро таб., 20 шт., нейтральный

    Цена 810 ₽
  • Локоген таб., 30 шт.
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    Локоген таб., 30 шт.

    Цена 2 534 ₽ вместо 2 560
  • Артнео капс., 35 г, 30 шт., нейтральный, 1 уп.
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    Артнео капс., 35 г, 30 шт., нейтральный, 1 уп.

    Цена 1 362 ₽ вместо 4 225
  • Таблетница на день / контейнер для лекарств
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    Таблетница на день / контейнер для лекарств

    Цена 494 ₽ вместо 999
  • Таблетница органайзер на неделю, контейнер для таблеток, бокс, на 7 дней, 4 приема, 28 ячеек
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    Таблетница органайзер на неделю, контейнер для таблеток, бокс, на 7 дней, 4 приема, 28 ячеек

    Цена 361 ₽ вместо 690
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    Реклама
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  • Таблетница на день 3 ячейки Oxitab синяя
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    Таблетница на день 3 ячейки Oxitab синяя

    Цена 241 ₽ вместо 520
  • Пилюля Таблетница, с делителем ( 2 отделения )
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    Пилюля Таблетница, с делителем ( 2 отделения )

    Цена 201 ₽ вместо 291
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