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Зодак таб. п/о плен., 10 мг, 10 шт.

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4.6
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Коротко о товаре

Артикул Маркета
3602872474
Тип препарата
Назначение
Действующее вещество
Возраст
от 6 лет
Инструкция
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Таблетки рекомендуется запивать стаканом воды.\u003Cbr\u003EВзрослым\u003Cbr\u003E10 мг (1 таблетка) 1 раз в сутки.\u003Cbr\u003EОтдельные группы пациентов\u003Cbr\u003EПациенты пожилого возраста\u003Cbr\u003EНет необходимости в снижении дозировки у пожилых пациентов, если функция почек не нарушена.\u003Cbr\u003EПациенты с почечной недостаточностью\u003Cbr\u003EПоскольку Зодак® выводится из организма в основном почками (см. подраздел \"Фармакокинетика\"), при невозможности альтернативного лечения пациентам с почечной недостаточностью режим дозирования препарата следует корректировать в зависимости от функции почек (величины клиренса креатинина КК).\u003Cbr\u003EКлиренс креатинина (КК) для мужчин можно рассчитать, исходя из концентрации сывороточного креатинина, по следующей формуле:\u003Cbr\u003EКК (мл/мин) = [140 - возраст (годы)] х масса тела (кг) / 72 х ККсыворот (мг/дл)\u003Cbr\u003EКК для женщин можно рассчитать, умножив полученное значение на коэффициент 0,85.\u003Cbr\u003EПациенты с нарушением функции печени\u003Cbr\u003EПациентам с нарушением только функции печени коррекции режима дозирования не требуется.\u003Cbr\u003EУ пациентов с нарушением и функции печени, и функции почек, рекомендуется коррекция дозирования (см. таблицу выше).\u003Cbr\u003EДети\u003Cbr\u003EДети от 6 до 12 лет\u003Cbr\u003E5 мг (1/2 таблетки) два раза в день\u003Cbr\u003EДети старше 12 лет\u003Cbr\u003E10 мг (1 таблетка) один раз в сутки.\u003Cbr\u003EИногда начальной дозы 5 мг (1/2 таблетки) может быть достаточно, если это позволяет достичь удовлетворительного контроля симптомов.\u003Cbr\u003EДетям с почечной недостаточностью дозу корректируют с учетом КК и массы тела."},{"name":"Побочные действия","value":"Частота развития нежелательных явлений определялась следующим образом: очень часто (≥ 1/10), часто (≥ 1/100, \u003C1/10), нечасто (≥ 1/1000, \u003C1/100), редко (≥ 1/10000, \u003C 1/1000), очень редко (\u003C 1/10000), частота неизвестна ( из-за недостаточности данных).\u003Cbr\u003EСо стороны крови и лимфатической системы\u003Cbr\u003EОчень редко: тромбоцитопения.\u003Cbr\u003EНарушения со стороны иммунной системы\u003Cbr\u003EРедко: реакции гиперчувствительности. Очень редко: анафилактический шок.\u003Cbr\u003EНарушения метаболизма и расстройства питания\u003Cbr\u003EЧастота неизвестна: повышение аппетита.\u003Cbr\u003EРасстройства со стороны психики\u003Cbr\u003EНечасто: возбуждение. Редко: агрессия, спутанность сознания, депрессия, галлюцинации, нарушение сна. Очень редко: тик. Частота неизвестна: суицидальные идеи, нарушения сна (включая кошмарные сновидения).\u003Cbr\u003EСо стороны нервной системы\u003Cbr\u003EНечасто: парестезии. Редко: судороги. Очень редко: извращение вкуса, дискинезия, дистония, обморок, тремор. Частота неизвестна: нарушение памяти, в том числе амнезия, глухота.\u003Cbr\u003EСо стороны органа зрения\u003Cbr\u003EОчень редко: нарушение аккомодации, нечеткость зрения, нистагм. Частота неизвестна: васкулит.\u003Cbr\u003EСо стороны органов слуха\u003Cbr\u003EЧастота неизвестна: вертиго.\u003Cbr\u003EСо стороны сердечно-сосудистой системы\u003Cbr\u003EРедко: тахикардия.\u003Cbr\u003EСо стороны пищеварительной системы\u003Cbr\u003EНечасто: диарея.\u003Cbr\u003EГепатобилиарные расстройства\u003Cbr\u003EРедко: печеночная недостаточность с изменением функциональных печеночных проб (повышение активности трансаминаз, щелочной фосфатазы, гамма-глутамилтрансферазы и билирубина).\u003Cbr\u003EСо стороны кожи\u003Cbr\u003EНечасто: сыпь, зуд. Редко: крапивница. Очень редко: ангионевротический отек, стойкая лекарственная эритема.\u003Cbr\u003EСо стороны мочевыделительной системы\u003Cbr\u003EОчень редко: дизурия, энурез. Частота неизвестна: задержка мочи.\u003Cbr\u003EСо стороны костно-мышечной системы:\u003Cbr\u003EЧастота неизвестна: артралгия.\u003Cbr\u003EОбщие расстройства\u003Cbr\u003EНечасто: астения, недомогание. Редко: периферические отеки.\u003Cbr\u003EИсследования\u003Cbr\u003EРедко: повышение массы тела.\u003Cbr\u003EОписание отдельных нежелательных реакций\u003Cbr\u003EПосле прекращения применения цетиризина были отмечены случаи зуда, (в том числе интенсивного зуда) и/или крапивницы.\u003Cbr\u003EОповещение о побочных реакциях: большое значение имеет система оповещения о подозреваемых побочных реакциях после регистрации лекарственного препарата.\u003Cbr\u003EЭто позволяет вести непрерывный мониторинг соотношения польза/риск лекарственного препарата."},{"name":"Фармакологическое действие","value":"Цетиризин - активное вещество препарата Зодак - является метаболитом гидроксизина, относится к группе конкурентных антагонистов гистамина и блокирует Н1-гистаминовые рецепторы.\u003Cbr\u003EВ дополнение к антигистаминному эффекту цетиризин предупреждает развитие и облегчает течение аллергических реакций: в дозе 10 мг один или два раза в день ингибирует позднюю фазу агрегации эозинофилов в коже и конъюнктиве пациентов, имеющих аллергические реакции.\u003Cbr\u003EКлиническая эффективность и безопасность\u003Cbr\u003EИсследования на здоровых добровольцах показали, что цетиризин в дозах 5 или 10 мг значительно ингибирует реакцию в виде сыпи и покраснения на введение в кожу гистамина в высокой концентрации, однако корреляция с эффективностью не установлена.\u003Cbr\u003EВ 6-недельном плацебо-контролируемом исследовании с участием 186 пациентов с аллергическим ринитом и сопутствующей бронхиальной астмой легкого и средне-тяжелого течения, показано, что прием цетиризина в дозе 10 мг один раз в сутки уменьшает симптомы ринита и не влияет на функцию легких.\u003Cbr\u003EРезультаты данного исследования подтверждают безопасность применения цетиризина у пациентов, страдающих аллергией и бронхиальной астмой легкого и среднетяжелого течения.\u003Cbr\u003EВ плацебо-контролируемом исследовании показано, что прием цетиризина в дозе 60 мг в сутки в течение 7 дней не вызывал клинически значимого удлинения интервала QT.\u003Cbr\u003EПрием цетиризина в рекомендуемой дозе показал улучшение качества жизни пациентов с круглогодичным и сезонным аллергическими ринитами.\u003Cbr\u003EВ клинических исследованиях показано, что цетиризин начинает действовать через 20 минут после приема, его эффект сохраняется до 24 часов.\u003Cbr\u003EДети\u003Cbr\u003EВ 35-дневном исследовании с участием пациентов в возрасте 5-12 лет не выявлено признаков невосприимчивости к антигистаминному эффекту цетиризина. Нормальная реакция кожи на гистамин восстанавливалась в течение трех дней после отмены препарата при его неоднократном применении."},{"name":"Фармакологическая группа","value":"противоаллергическое средство - H1-гистаминовых рецепторов блокатор"},{"name":"Форма выпуска","value":"таблетки, покрытые пленочной оболочкой"},{"name":"Способ применения/введения","value":"пероральный","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-allergii","categoryId":"15756502","navnodeId":"72464","glfilters":["35947170:36763744"]}}},{"name":"Минимальный возраст применения","value":"от 6 лет"},{"name":"Условия хранения","value":"Хранить при температуре не выше 25 °C.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы\u003Cbr\u003EПри однократном приеме препарата в дозе 50 мг наблюдались следующие симптомы: спутанность сознания, диарея, головокружение, повышенная утомляемость, головная боль, недомогание, мидриаз, зуд, беспокойство, слабость, седативный эффект, сонливость, ступор, тахикардия, тремор, задержка мочи.\u003Cbr\u003EЛечение: сразу после приема препарата - промывание желудка или стимуляция рвоты. Рекомендуется прием активированного угля, проведение симптоматической и поддерживающей терапии. Специфического антидота нет. Гемодиализ неэффективен."},{"name":"Применение при беременности и кормлении грудью","value":"При анализе проспективных данных более чем 700 случаев исходов беременности не выявлено случаев формирования пороков развития, эмбриональной и неонатальной токсичности с четкой причинно-следственной связью.\u003Cbr\u003EЭкспериментальные исследования на животных не выявили каких-либо прямых или косвенных неблагоприятных эффектов цетиризина на развивающийся плод (в том числе в постнатальном периоде), течение беременности и родов.\u003Cbr\u003EАдекватных и строго контролируемых клинических исследований по безопасности применения препарата во время беременности не проводилось, поэтому Зодак не следует применять при беременности.\u003Cbr\u003EГрудное вскармливание\u003Cbr\u003EЦетиризин выделяется с грудным молоком в концентрации от 25% до 90% от концентрации препарата в плазме крови в зависимости от времени после назначения. В период грудного вскармливания Зодак применяют после консультации с врачом, если предполагаемая польза для матери превышает потенциальный риск для ребенка.\u003Cbr\u003EФертильность\u003Cbr\u003EДоступные данные о влиянии на фертильность человека ограничены, однако отрицательного влияния на фертильность не выявлено."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"При объективной оценке способности к вождению автотранспорта и управлению механизмами достоверно не выявлено каких-либо нежелательных явлений при приеме препарата в рекомендуемой дозе. Однако пациентам с проявлениями сонливости на фоне приема препарата целесообразно воздерживаться от управления автомобилем, занятиями потенциально опасными видами деятельности или управлением механизмами, требующими повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"Рекомендовано соблюдать осторожность при применении цетиризина одновременно с алкоголем.\u003Cbr\u003EУ пациентов с повреждением спинного мозга, гиперплазией предстательной железы, а также при наличии других предрасполагающих факторов к задержке мочи, требуется соблюдение осторожности, так как цетиризин может увеличивать риск задержки мочи. Осторожность следует соблюдать у пациентов с эпилепсией и повышенной судорожной готовностью.\u003Cbr\u003EПеред назначением аллергологических проб рекомендован трехдневный \"отмывочный\" период ввиду того, что H1 - гистаминовых рецепторов блокаторы ингибируют развитие кожных аллергических реакций.\u003Cbr\u003EЦетиризин в таблетках, покрытых пленочной оболочкой, не должен назначаться пациентам с наследственной непереносимостью галактозы, недостатке лактазы или синдроме глюкозо-галактозной мальабсорбции.\u003Cbr\u003EПосле прекращения применения цетиризина может появиться зуд и/или крапивница, даже если эти симптомы отсутствовали в начале лечения. В некоторых случаях симптомы могут быть интенсивными и требовать возобновления приема цетиризина. Симптомы, исчезают при возобновлении приема цетиризина.\u003Cbr\u003EДети\u003Cbr\u003EЦетиризин в форме таблеток, покрытых пленочной оболочкой, не рекомендуется назначать детям до 6 лет, поскольку данная лекарственная форма не позволяет использовать подходящую дозировку у этой возрастной группы. Рекомендуется использовать педиатрическую лекарственную форму (капли для приема внутрь)."},{"name":"Взаимодействие","value":"На основании анализа фармакодинамики, фармакокинетики цетиризина, взаимодействие с другими лекарственными препаратами маловероятно.\u003Cbr\u003EНе было отмечено значимых взаимодействий с псевдоэфедрином и теофиллином (в дозе 400 мг в сутки) в специальных исследованиях лекарственного взаимодействия. Одновременное применение цетиризина с алкоголем и другими препаратами, угнетающими ЦНС, может способствовать дальнейшему снижению концентрации внимания и быстроты реакций, хотя цетиризин не усиливает эффект алкоголя (при его концентрации в крови 0,5 г/л)."},{"name":"Регистрационный номер","value":"П N013867/01"},{"name":"Дата государственной регистрации","value":"09.12.2011"},{"name":"Владелец регистрационного удостоверения","value":"Санофи Россия","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-allergii","categoryId":"15756502","navnodeId":"72464","glfilters":["34324371:35649313","7893318:16606665"]}}},{"name":"Изготовитель","value":"Zentiva"},{"name":"Страна бренда","value":"Франция"},{"name":"Страна-производитель","value":"Чехия"},{"name":"Название препарата","value":"Зодак","transition":{"type":"catalog","params":{"categorySlug":"sredstva-ot-allergii","categoryId":"15756502","navnodeId":"72464","glfilters":["17796364:17876245"]}}},{"name":"Срок годности","value":"35 мес."}]}},"fullSpecsGrouped":{"4957931830642772740":{"groups":[{"name":"Общие характеристики","items":[{"name":"Тип препарата","value":"лекарственный препарат"},{"name":"Органы и системы","value":"дыхательная система, кожа"},{"name":"Назначение","value":"аллергический конъюнктивит, аллергический ринит, аллергический риноконъюнктивит, крапивница, сезонная аллергия, чихание"},{"name":"Показания к применению","value":"Показан у взрослых и детей с 6 лет и старше для облегчения:\u003Cbr\u003E- назальных и глазных симптомов круглогодичного (персистирующего) и сезонного (интермиттирующего) аллергического ринита и аллергического конъюнктивита: зуда, чиханья, заложенности носа, ринореи, слезотечения, гиперемии конъюнктивы;\u003Cbr\u003E- симптомов хронической идиопатической крапивницы."},{"name":"Противопоказания","value":"Повышенная чувствительность к цетиризину, гидроксизину или производным пиперазина, а также другим компонентам препарата;\u003Cbr\u003E- терминальная стадия почечной недостаточности (КК \u003C 10 мл/мин);\u003Cbr\u003E- наследственная непереносимость галактозы, недостаточность лактазы или синдром глюкозо-галактозной мальабсорбции;\u003Cbr\u003E- беременность;\u003Cbr\u003E- детский возраст до 6 лет (для данной лекарственной формы)."},{"name":"Состав","value":"В одной таблетке содержится:\u003Cbr\u003Eактивное вещество: цетиризина дигидрохлорид 10,00 мг;\u003Cbr\u003Eвспомогательные вещества:\u003Cbr\u003Eядро: лактозы моногидрат, крахмал кукурузный, повидон 30, магния стеарат;\u003Cbr\u003Eоболочка: гипромеллоза 2910/5, макрогол-6000, тальк, титана диоксид, симетикона эмульсия SE 4."},{"name":"Действующее вещество","value":"Цетиризин"},{"name":"Способ применения и дозы","value":"Внутрь. Таблетки рекомендуется запивать стаканом воды.\u003Cbr\u003EВзрослым\u003Cbr\u003E10 мг (1 таблетка) 1 раз в сутки.\u003Cbr\u003EОтдельные группы пациентов\u003Cbr\u003EПациенты пожилого возраста\u003Cbr\u003EНет необходимости в снижении дозировки у пожилых пациентов, если функция почек не нарушена.\u003Cbr\u003EПациенты с почечной недостаточностью\u003Cbr\u003EПоскольку Зодак® выводится из организма в основном почками (см. подраздел \"Фармакокинетика\"), при невозможности альтернативного лечения пациентам с почечной недостаточностью режим дозирования препарата следует корректировать в зависимости от функции почек (величины клиренса креатинина КК).\u003Cbr\u003EКлиренс креатинина (КК) для мужчин можно рассчитать, исходя из концентрации сывороточного креатинина, по следующей формуле:\u003Cbr\u003EКК (мл/мин) = [140 - возраст (годы)] х масса тела (кг) / 72 х ККсыворот (мг/дл)\u003Cbr\u003EКК для женщин можно рассчитать, умножив полученное значение на коэффициент 0,85.\u003Cbr\u003EПациенты с нарушением функции печени\u003Cbr\u003EПациентам с нарушением только функции печени коррекции режима дозирования не требуется.\u003Cbr\u003EУ пациентов с нарушением и функции печени, и функции почек, рекомендуется коррекция дозирования (см. таблицу выше).\u003Cbr\u003EДети\u003Cbr\u003EДети от 6 до 12 лет\u003Cbr\u003E5 мг (1/2 таблетки) два раза в день\u003Cbr\u003EДети старше 12 лет\u003Cbr\u003E10 мг (1 таблетка) один раз в сутки.\u003Cbr\u003EИногда начальной дозы 5 мг (1/2 таблетки) может быть достаточно, если это позволяет достичь удовлетворительного контроля симптомов.\u003Cbr\u003EДетям с почечной недостаточностью дозу корректируют с учетом КК и массы тела."},{"name":"Побочные действия","value":"Частота развития нежелательных явлений определялась следующим образом: очень часто (≥ 1/10), часто (≥ 1/100, \u003C1/10), нечасто (≥ 1/1000, \u003C1/100), редко (≥ 1/10000, \u003C 1/1000), очень редко (\u003C 1/10000), частота неизвестна ( из-за недостаточности данных).\u003Cbr\u003EСо стороны крови и лимфатической системы\u003Cbr\u003EОчень редко: тромбоцитопения.\u003Cbr\u003EНарушения со стороны иммунной системы\u003Cbr\u003EРедко: реакции гиперчувствительности. Очень редко: анафилактический шок.\u003Cbr\u003EНарушения метаболизма и расстройства питания\u003Cbr\u003EЧастота неизвестна: повышение аппетита.\u003Cbr\u003EРасстройства со стороны психики\u003Cbr\u003EНечасто: возбуждение. Редко: агрессия, спутанность сознания, депрессия, галлюцинации, нарушение сна. Очень редко: тик. Частота неизвестна: суицидальные идеи, нарушения сна (включая кошмарные сновидения).\u003Cbr\u003EСо стороны нервной системы\u003Cbr\u003EНечасто: парестезии. Редко: судороги. Очень редко: извращение вкуса, дискинезия, дистония, обморок, тремор. Частота неизвестна: нарушение памяти, в том числе амнезия, глухота.\u003Cbr\u003EСо стороны органа зрения\u003Cbr\u003EОчень редко: нарушение аккомодации, нечеткость зрения, нистагм. Частота неизвестна: васкулит.\u003Cbr\u003EСо стороны органов слуха\u003Cbr\u003EЧастота неизвестна: вертиго.\u003Cbr\u003EСо стороны сердечно-сосудистой системы\u003Cbr\u003EРедко: тахикардия.\u003Cbr\u003EСо стороны пищеварительной системы\u003Cbr\u003EНечасто: диарея.\u003Cbr\u003EГепатобилиарные расстройства\u003Cbr\u003EРедко: печеночная недостаточность с изменением функциональных печеночных проб (повышение активности трансаминаз, щелочной фосфатазы, гамма-глутамилтрансферазы и билирубина).\u003Cbr\u003EСо стороны кожи\u003Cbr\u003EНечасто: сыпь, зуд. Редко: крапивница. Очень редко: ангионевротический отек, стойкая лекарственная эритема.\u003Cbr\u003EСо стороны мочевыделительной системы\u003Cbr\u003EОчень редко: дизурия, энурез. Частота неизвестна: задержка мочи.\u003Cbr\u003EСо стороны костно-мышечной системы:\u003Cbr\u003EЧастота неизвестна: артралгия.\u003Cbr\u003EОбщие расстройства\u003Cbr\u003EНечасто: астения, недомогание. Редко: периферические отеки.\u003Cbr\u003EИсследования\u003Cbr\u003EРедко: повышение массы тела.\u003Cbr\u003EОписание отдельных нежелательных реакций\u003Cbr\u003EПосле прекращения применения цетиризина были отмечены случаи зуда, (в том числе интенсивного зуда) и/или крапивницы.\u003Cbr\u003EОповещение о побочных реакциях: большое значение имеет система оповещения о подозреваемых побочных реакциях после регистрации лекарственного препарата.\u003Cbr\u003EЭто позволяет вести непрерывный мониторинг соотношения польза/риск лекарственного препарата."},{"name":"Фармакологическое действие","value":"Цетиризин - активное вещество препарата Зодак - является метаболитом гидроксизина, относится к группе конкурентных антагонистов гистамина и блокирует Н1-гистаминовые рецепторы.\u003Cbr\u003EВ дополнение к антигистаминному эффекту цетиризин предупреждает развитие и облегчает течение аллергических реакций: в дозе 10 мг один или два раза в день ингибирует позднюю фазу агрегации эозинофилов в коже и конъюнктиве пациентов, имеющих аллергические реакции.\u003Cbr\u003EКлиническая эффективность и безопасность\u003Cbr\u003EИсследования на здоровых добровольцах показали, что цетиризин в дозах 5 или 10 мг значительно ингибирует реакцию в виде сыпи и покраснения на введение в кожу гистамина в высокой концентрации, однако корреляция с эффективностью не установлена.\u003Cbr\u003EВ 6-недельном плацебо-контролируемом исследовании с участием 186 пациентов с аллергическим ринитом и сопутствующей бронхиальной астмой легкого и средне-тяжелого течения, показано, что прием цетиризина в дозе 10 мг один раз в сутки уменьшает симптомы ринита и не влияет на функцию легких.\u003Cbr\u003EРезультаты данного исследования подтверждают безопасность применения цетиризина у пациентов, страдающих аллергией и бронхиальной астмой легкого и среднетяжелого течения.\u003Cbr\u003EВ плацебо-контролируемом исследовании показано, что прием цетиризина в дозе 60 мг в сутки в течение 7 дней не вызывал клинически значимого удлинения интервала QT.\u003Cbr\u003EПрием цетиризина в рекомендуемой дозе показал улучшение качества жизни пациентов с круглогодичным и сезонным аллергическими ринитами.\u003Cbr\u003EВ клинических исследованиях показано, что цетиризин начинает действовать через 20 минут после приема, его эффект сохраняется до 24 часов.\u003Cbr\u003EДети\u003Cbr\u003EВ 35-дневном исследовании с участием пациентов в возрасте 5-12 лет не выявлено признаков невосприимчивости к антигистаминному эффекту цетиризина. Нормальная реакция кожи на гистамин восстанавливалась в течение трех дней после отмены препарата при его неоднократном применении."},{"name":"Фармакологическая группа","value":"противоаллергическое средство - H1-гистаминовых рецепторов блокатор"},{"name":"Форма выпуска","value":"таблетки, покрытые пленочной оболочкой"},{"name":"Способ применения/введения","value":"пероральный"},{"name":"Минимальный возраст применения","value":"от 6 лет"}]},{"name":"Дополнительно","items":[{"name":"Условия хранения","value":"Хранить при температуре не выше 25 °C.\u003Cbr\u003EХранить в недоступном для детей месте."},{"name":"Передозировка","value":"Симптомы\u003Cbr\u003EПри однократном приеме препарата в дозе 50 мг наблюдались следующие симптомы: спутанность сознания, диарея, головокружение, повышенная утомляемость, головная боль, недомогание, мидриаз, зуд, беспокойство, слабость, седативный эффект, сонливость, ступор, тахикардия, тремор, задержка мочи.\u003Cbr\u003EЛечение: сразу после приема препарата - промывание желудка или стимуляция рвоты. Рекомендуется прием активированного угля, проведение симптоматической и поддерживающей терапии. Специфического антидота нет. Гемодиализ неэффективен."},{"name":"Применение при беременности и кормлении грудью","value":"При анализе проспективных данных более чем 700 случаев исходов беременности не выявлено случаев формирования пороков развития, эмбриональной и неонатальной токсичности с четкой причинно-следственной связью.\u003Cbr\u003EЭкспериментальные исследования на животных не выявили каких-либо прямых или косвенных неблагоприятных эффектов цетиризина на развивающийся плод (в том числе в постнатальном периоде), течение беременности и родов.\u003Cbr\u003EАдекватных и строго контролируемых клинических исследований по безопасности применения препарата во время беременности не проводилось, поэтому Зодак не следует применять при беременности.\u003Cbr\u003EГрудное вскармливание\u003Cbr\u003EЦетиризин выделяется с грудным молоком в концентрации от 25% до 90% от концентрации препарата в плазме крови в зависимости от времени после назначения. В период грудного вскармливания Зодак применяют после консультации с врачом, если предполагаемая польза для матери превышает потенциальный риск для ребенка.\u003Cbr\u003EФертильность\u003Cbr\u003EДоступные данные о влиянии на фертильность человека ограничены, однако отрицательного влияния на фертильность не выявлено."},{"name":"Влияние на способность управлять транспортом и механизмами","value":"При объективной оценке способности к вождению автотранспорта и управлению механизмами достоверно не выявлено каких-либо нежелательных явлений при приеме препарата в рекомендуемой дозе. Однако пациентам с проявлениями сонливости на фоне приема препарата целесообразно воздерживаться от управления автомобилем, занятиями потенциально опасными видами деятельности или управлением механизмами, требующими повышенной концентрации внимания и быстроты психомоторных реакций."},{"name":"Особые указания","value":"Рекомендовано соблюдать осторожность при применении цетиризина одновременно с алкоголем.\u003Cbr\u003EУ пациентов с повреждением спинного мозга, гиперплазией предстательной железы, а также при наличии других предрасполагающих факторов к задержке мочи, требуется соблюдение осторожности, так как цетиризин может увеличивать риск задержки мочи. Осторожность следует соблюдать у пациентов с эпилепсией и повышенной судорожной готовностью.\u003Cbr\u003EПеред назначением аллергологических проб рекомендован трехдневный \"отмывочный\" период ввиду того, что H1 - гистаминовых рецепторов блокаторы ингибируют развитие кожных аллергических реакций.\u003Cbr\u003EЦетиризин в таблетках, покрытых пленочной оболочкой, не должен назначаться пациентам с наследственной непереносимостью галактозы, недостатке лактазы или синдроме глюкозо-галактозной мальабсорбции.\u003Cbr\u003EПосле прекращения применения цетиризина может появиться зуд и/или крапивница, даже если эти симптомы отсутствовали в начале лечения. В некоторых случаях симптомы могут быть интенсивными и требовать возобновления приема цетиризина. Симптомы, исчезают при возобновлении приема цетиризина.\u003Cbr\u003EДети\u003Cbr\u003EЦетиризин в форме таблеток, покрытых пленочной оболочкой, не рекомендуется назначать детям до 6 лет, поскольку данная лекарственная форма не позволяет использовать подходящую дозировку у этой возрастной группы. Рекомендуется использовать педиатрическую лекарственную форму (капли для приема внутрь)."},{"name":"Взаимодействие","value":"На основании анализа фармакодинамики, фармакокинетики цетиризина, взаимодействие с другими лекарственными препаратами маловероятно.\u003Cbr\u003EНе было отмечено значимых взаимодействий с псевдоэфедрином и теофиллином (в дозе 400 мг в сутки) в специальных исследованиях лекарственного взаимодействия. Одновременное применение цетиризина с алкоголем и другими препаратами, угнетающими ЦНС, может способствовать дальнейшему снижению концентрации внимания и быстроты реакций, хотя цетиризин не усиливает эффект алкоголя (при его концентрации в крови 0,5 г/л)."},{"name":"Регистрационный номер","value":"П N013867/01"},{"name":"Дата государственной регистрации","value":"09.12.2011"},{"name":"Владелец регистрационного удостоверения","value":"Санофи Россия"},{"name":"Изготовитель","value":"Zentiva"},{"name":"Страна бренда","value":"Франция"},{"name":"Страна-производитель","value":"Чехия"},{"name":"Название препарата","value":"Зодак"},{"name":"Срок годности","value":"35 мес."}]}],"transitionId":"tr_10358240073432295336"}}}}
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
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Цена с картой Яндекс Пэй:117 ₽

Скидка: 1%
–1 %
Вместо: 118 ₽
  • 18 июня, курьер Маркета • 249 ₽
  • Завтра, самовывоз • 0 ₽
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Инструкция

Показания к применению

Показан у взрослых и детей с 6 лет и старше для облегчения:
- назальных и глазных симптомов круглогодичного (персистирующего) и сезонного (интермиттирующего) аллергического ринита и аллергического конъюнктивита: зуда, чиханья, заложенности носа, ринореи, слезотечения, гиперемии конъюнктивы;
- симптомов хронической идиопатической крапивницы.

Противопоказания

Повышенная чувствительность к цетиризину, гидроксизину или производным пиперазина, а также другим компонентам препарата;
- терминальная стадия почечной недостаточности (КК < 10 мл/мин);
- наследственная непереносимость галактозы, недостаточность лактазы или синдром глюкозо-галактозной мальабсорбции;
- беременность;
- детский возраст до 6 лет (для данной лекарственной формы).

Способ применения и дозы

Внутрь. Таблетки рекомендуется запивать стаканом воды.
Взрослым
10 мг (1 таблетка) 1 раз в сутки.
Отдельные группы пациентов
Пациенты пожилого возраста
Нет необходимости в снижении дозировки у пожилых пациентов, если функция почек не нарушена.
Пациенты с почечной недостаточностью
Поскольку Зодак® выводится из организма в основном почками (см. подраздел "Фармакокинетика"), при невозможности альтернативного лечения пациентам с почечной недостаточностью режим дозирования препарата следует корректировать в зависимости от функции почек (величины клиренса креатинина КК).
Клиренс креатинина (КК) для мужчин можно рассчитать, исходя из концентрации сывороточного креатинина, по следующей формуле:
КК (мл/мин) = [140 - возраст (годы)] х масса тела (кг) / 72 х ККсыворот (мг/дл)
КК для женщин можно рассчитать, умножив полученное значение на коэффициент 0,85.
Пациенты с нарушением функции печени
Пациентам с нарушением только функции печени коррекции режима дозирования не требуется.
У пациентов с нарушением и функции печени, и функции почек, рекомендуется коррекция дозирования (см. таблицу выше).
Дети
Дети от 6 до 12 лет
5 мг (1/2 таблетки) два раза в день
Дети старше 12 лет
10 мг (1 таблетка) один раз в сутки.
Иногда начальной дозы 5 мг (1/2 таблетки) может быть достаточно, если это позволяет достичь удовлетворительного контроля симптомов.
Детям с почечной недостаточностью дозу корректируют с учетом КК и массы тела.
Полная инструкция
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Зодак таб. п/о плен.
Зодак таб. п/о плен., 10 мг, 10 шт.
4.6
(9)
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Задать вопрос
Инструкция

Цена с картой Яндекс Пэй:117 ₽

Скидка: 1%
–1 %
Вместо: 118 ₽
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4.6
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У продавца:9 оценок·2 отзыва
У всех продавцов:32 оценки·15 отзывов
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user avatar
3 месяца назад • Инна К. • Куплен на Маркете
Достоинства: Быстро помогает, без сонливости справляется с аллергией
Недостатки: Минусов нет, намного лучше супрастина
Комментарий: Рекомендую, хорошее средство от аллергии
user avatar
7 месяцев назад • Данил • Куплен на Маркете
Достоинства: Всё супер
Недостатки: Нету
Комментарий: Вс хорошо
Посмотреть все отзывы на Маркете
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    Таблетница - брелок на день, 1 раздел, контейнер для таблеток металлический маленький (черный матовый)

    Цена 209 ₽ вместо 599
  • Таблетница органайзер на неделю, контейнер для таблеток, бокс, на 7 дней, 4 приема, 28 ячеек
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    Таблетница органайзер на неделю, контейнер для таблеток, бокс, на 7 дней, 4 приема, 28 ячеек

    Цена 361 ₽ вместо 690
  • Таблетница на 7 дней / органайзер / бокс / контейнер на неделю для хранения таблеток и лекарств 4 приема, Прозрачный, Daswerk
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    Таблетница на 7 дней / органайзер / бокс / контейнер на неделю для хранения таблеток и лекарств 4 приема, Прозрачный, Daswerk

    Цена 309 ₽ вместо 414
  • Назаваль спрей наз. дозир. фл., 500 мг, 19 г, 200 шт.
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    Назаваль спрей наз. дозир. фл., 500 мг, 19 г, 200 шт.

    Цена 563 ₽ вместо 569
  • Таблетница на день мини для капсул контейнер для таблеток белый
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    Таблетница на день мини для капсул контейнер для таблеток белый

    Цена 282 ₽ вместо 750
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    Реклама
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  • Фитол- АллергоЩит капс., 30 мл, 30 шт.
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    Фитол- АллергоЩит капс., 30 мл, 30 шт.

    Цена 499 ₽ вместо 509
  • Солхинол крем антиаллергический, 30 мл, 1 шт.
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    Солхинол крем антиаллергический, 30 мл, 1 шт.

    Цена 427 ₽
  • Таблетница пилюля на один день Мини, синяя (контейнер для таблеток)
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    Таблетница пилюля на один день Мини, синяя (контейнер для таблеток)

    Цена 157 ₽ вместо 265
  • Таблетница органайзер на неделю утро / день / вечер; Органайзер для таблеток на 7 дней; Карманная аптечка
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    Таблетница органайзер на неделю утро / день / вечер; Органайзер для таблеток на 7 дней; Карманная аптечка

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    Таблетница компактная /органайзер аптечка/ контейнер для таблеток БАД Panda_Home (синего цвета)

    Цена 245 ₽ вместо 263
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    Таблетница на неделю AXLER контейнер органайзер для таблеток, большая таблеточница бокс для лекарств на 7 дней, кейс на 4 приема: утро день вечер ночь

    Цена 343 ₽ вместо 442
  • Таблетница на день 3 ячейки Oxitab синяя
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    Таблетница на день 3 ячейки Oxitab синяя

    Цена 241 ₽ вместо 520
  • Таблетница на 7 дней / органайзер / бокс / контейнер на неделю для хранения таблеток и лекарств 4 приема Clear Daswerk
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    Таблетница на 7 дней / органайзер / бокс / контейнер на неделю для хранения таблеток и лекарств 4 приема Clear Daswerk

    Цена 400 ₽ вместо 637
  • Контейнер для хранения/таблетница/кейс для таблеток
    {"widgets":{"@marketfront/SnippetConstructor/Gallery":{"/content/page/fancyPage/recommendationRoll/content/lazyGenerator/initialContent/recomLayoutItem_21#1:1937765050_17/content/content/gallery":{"title":"Контейнер для хранения/таблетница/кейс для таблеток","images":[{"src":"https://avatars.mds.yandex.net/get-mpic/12555301/2a0000018f7d7ff650e6e8b045fc5300942e/orig","srcSet":"https://avatars.mds.yandex.net/get-mpic/12555301/2a0000018f7d7ff650e6e8b045fc5300942e/120x160 120w, https://avatars.mds.yandex.net/get-mpic/12555301/2a0000018f7d7ff650e6e8b045fc5300942e/180x240 180w, https://avatars.mds.yandex.net/get-mpic/12555301/2a0000018f7d7ff650e6e8b045fc5300942e/240x320 240w, https://avatars.mds.yandex.net/get-mpic/12555301/2a0000018f7d7ff650e6e8b045fc5300942e/300x400 300w, https://avatars.mds.yandex.net/get-mpic/12555301/2a0000018f7d7ff650e6e8b045fc5300942e/600x800 600w","sizes":"(max-width: 1456px) 15vw, 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    Контейнер для хранения/таблетница/кейс для таблеток

    Цена 367 ₽ вместо 699
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