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Описание

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Мелатонин-СЗ таб. п/о плен., 3 мг, 60 шт., 1 уп.

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4.8

(66)

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Количество штук в упаковке, шт.: 60

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Коротко о товаре

Артикул Маркета

3123240437

Тип препарата

лекарственный препарат

Назначение

бессонница, десинхроноз, нарушение сна

Действующее вещество

Мелатонин

Возраст

от 18 лет

Инструкция

Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.

Где купить

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510 ₽

14-15 мая, самовывоз • 0 ₽

ЕАПТЕКА

Рейтинг 5 из 5

95Котзывов

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сна.\u003Cbr\u003EПри десинхронозе в качестве адаптогена при смене часовых поясов - за 1 день до перелета и в последующие 2-5 дней - по 3 мг за 30-40 минут до сна.\u003Cbr\u003EМаксимальная суточная доза - 6 мг.\u003Cbr\u003EПожилые пациенты\u003Cbr\u003EС возрастом происходит снижение метаболизма мелатонина, что необходимо учитывать при выборе режима дозирования для пожилых пациентов.\u003Cbr\u003EС учетом этого у пациентов пожилого возраста, возможен прием препарата за 60-90 минут до сна.\u003Cbr\u003EПациентам с тяжелой почечной недостаточностью применение препарата не рекомендуется."},{"description":"","filters":[{"id":15767998,"name":"Побочные действия"}],"isMainProperty":false,"name":"Побочные действия","value":"Классификация частоты развития побочных эффектов согласно рекомендациям Всемирной Организации Здравоохранения: очень часто (≥1/10), часто (от ≥1/100 до \u003C1/10), нечасто (от ≥1/1000 до \u003C1/100), редко (от ≥1/10000 до \u003C1/1000), очень редко (\u003C 1/10000), включая отдельные сообщения; частота неизвестна (по имеющимся данным установить частоту возникновения не представляется возможным).\u003Cbr\u003EИнфекционные и паразитарные заболевания:\u003Cbr\u003Eредко: опоясывающий герпес.\u003Cbr\u003EНарушения со стороны крови и лимфатической системы:\u003Cbr\u003Eредко: лейкопения, тромбоцитопения.\u003Cbr\u003EНарушения со стороны иммунной системы:\u003Cbr\u003Eчастота неизвестна: реакции гиперчувствительности.\u003Cbr\u003EНарушения со стороны обмена веществ и питания:\u003Cbr\u003Eредко: гипертриглицеридемия, гипокалиемия, гипонатриемия.\u003Cbr\u003EНарушения психики:\u003Cbr\u003Eнечасто: раздражительность, нервозность, беспокойство, бессонница, необычные сновидения, ночные кошмары, тревога;\u003Cbr\u003Eредко: перемены настроения, агрессия, ажитация, плаксивость, симптомы стресса, дезориентация, раннее утреннее пробуждение, повышение либидо, сниженное настроение, депрессия.\u003Cbr\u003EНарушения со стороны нервной системы:\u003Cbr\u003Eнечасто: мигрень, головная боль, вялость, психомоторная гиперактивность, головокружение, сонливость;\u003Cbr\u003Eредко: обморок, нарушение памяти, нарушение концентрации внимания, делирий, синдром \"беспокойных ног\", плохое качество сна, парестезии.\u003Cbr\u003EНарушения со стороны органа зрения:\u003Cbr\u003Eредко: снижение остроты зрения, нечеткость зрения, повышенное слезотечение.\u003Cbr\u003EНарушения со стороны органа слуха и лабиринтные нарушения:\u003Cbr\u003Eредко: вертиго, позиционное вертиго.\u003Cbr\u003EНарушения со стороны сердечно-сосудистой системы:\u003Cbr\u003Eнечасто: артериальная гипертензия;\u003Cbr\u003Eредко: стенокардия напряжения, ощущение сердцебиения, приливы.\u003Cbr\u003EНарушения со стороны желудочно-кишечного тракта:\u003Cbr\u003Eнечасто: абдоминальная боль, абдоминальная боль в верхней части живота, диспепсия, язвенный стоматит, сухость во рту, тошнота;\u003Cbr\u003Eредко: гастроэзофагеальная болезнь, желудочно-кишечное нарушение или расстройство, буллезный стоматит, язвенный глоссит, рвота, усиление перистальтики, вздутие живота, гиперсекреция слюны, неприятный запах изо рта, абдоминальный дискомфорт, дискинезия желудка, гастрит.\u003Cbr\u003EНарушения со стороны печени и желчевыводящих путей:\u003Cbr\u003Eнечасто: гипербилирубинемия.\u003Cbr\u003EНарушения со стороны кожи и подкожных тканей:\u003Cbr\u003Eнечасто: дерматит, потливость по ночам, зуд и генерализованный зуд, сыпь, сухость кожи;\u003Cbr\u003Eредко: экзема, эритема, дерматит рук, псориаз, генерализованная сыпь, зудящая сыпь, поражение ногтей;\u003Cbr\u003Eчастота неизвестна: отек Квинке, отек слизистой оболочки полости рта, отек языка.\u003Cbr\u003EНарушения со стороны скелетно-мышечной и соединительной ткани:\u003Cbr\u003Eнечасто: боль в конечностях;\u003Cbr\u003Eредко: артрит, мышечный спазм, боль в шее, ночные судороги.\u003Cbr\u003EНарушения со стороны почек и мочевыводящих путей:\u003Cbr\u003Eнечасто: глюкозурия, протеинурия;\u003Cbr\u003Eредко: полиурия, гематурия, никтурия.\u003Cbr\u003EНарушения со стороны половых органов и грудной железы:\u003Cbr\u003Eнечасто: менопаузальные симптомы; редко: приапизм, простатит;\u003Cbr\u003Eчастота неизвестна: галакторея.\u003Cbr\u003EОбщие расстройства и нарушения в месте введения:\u003Cbr\u003Eнечасто: астения, боль в груди;\u003Cbr\u003Eредко: утомляемость, боль, жажда."},{"description":"","filters":[{"id":15768001,"name":"Фармакологическое действие"}],"isMainProperty":false,"name":"Фармакологическое действие","value":"Синтетический аналог гормона шишковидного тела (эпифиза); оказывает адаптогенное, седативное, снотворное действие. Нормализует циркадные ритмы. Увеличивает концентрацию гамма-аминомасляной кислоты (ГАМК) и серотонина в среднем мозге и гипоталамусе, изменяет активность пиридоксалькиназы, участвующей в синтезе ГАМК, дофамина и серотонина. Регулирует цикл сон-бодрствование, суточные изменения локомоторной активности и температуры тела, положительно влияет на интеллектуально-мнестические функции мозга, на эмоционально-личностную сферу. Способствует организации биологического ритма и нормализации ночного сна. Улучшает качество сна, ускоряет засыпание, регулирует нейроэндокринные функции. Адаптирует организм метеочувствительных людей к изменениям погодных условий."},{"description":"","filters":[{"id":34045110,"name":"Фармакологическая группа"}],"isMainProperty":false,"name":"Фармакологическая группа","value":"адаптогенное средство"},{"description":"","filters":[{"id":27141511,"name":"Форма выпуска для карточки"}],"isMainProperty":false,"name":"Форма выпуска","value":"таблетки, покрытые пленочной оболочкой"},{"description":"","filters":[{"id":35947170,"name":"Способ применения/введения"}],"isMainProperty":false,"name":"Способ применения/введения","value":"пероральный"},{"description":"","filters":[{"id":23679511,"name":"Минимальный возраст применения"},{"id":16082123,"name":"С рождения"}],"isMainProperty":false,"name":"Минимальный возраст применения","value":"от 18 лет"}]},{"name":"Дополнительно","specs":[{"description":"","filters":[{"id":15767999,"name":"Условия хранения"}],"isMainProperty":false,"name":"Условия хранения","value":"В защищенном от света месте, при температуре не выше 25 °С. Хранить в недоступном для детей месте."},{"description":"","filters":[{"id":15768014,"name":"Передозировка"}],"isMainProperty":false,"name":"Передозировка","value":"По имеющимся литературным данным, применение мелатонина в суточной дозе до 300 мг не вызывало клинически значимых нежелательных реакций. Наблюдались гиперемия, спазмы в брюшной полости, диарея, головная боль и скотома при применении мелатонина в дозах 3000-6600 мг в течение нескольких недель. При применении очень высоких доз мелатонина (до 1 г) наблюдалась непроизвольная потеря сознания.\u003Cbr\u003EПри передозировке возможно развитие сонливости.\u003Cbr\u003EЛечение - промывание желудка и применение активированного угля, симптоматическая терапия.\u003Cbr\u003EКлиренс активного вещества предполагается в пределах 12 часов после приема внутрь."},{"description":"","filters":[{"id":15768015,"name":"Применение при беременности и кормлении грудью"}],"isMainProperty":false,"name":"Применение при беременности и кормлении грудью","value":"Препарат противопоказан к применению при беременности и в период грудного вскармливания."},{"description":"","filters":[{"id":17360993,"name":"Влияние на способность управлять транспортом и механизмами"}],"isMainProperty":false,"name":"Влияние на способность управлять транспортом и механизмами","value":"Препарат Мелатонин-СЗ вызывает сонливость, в связи с этим в период лечения следует воздержаться от вождения автотранспорта и занятий потенциально опасными видами деятельности, требующими повышенной концентрации внимания и быстроты психомоторных реакций."},{"description":"","filters":[{"id":15771167,"name":"Особые указания"}],"isMainProperty":false,"name":"Особые указания","value":"В период применения препарата Мелатонин-СЗ рекомендуется избегать пребывания на ярком свету.\u003Cbr\u003EНеобходимо проинформировать женщин, желающих забеременеть, о наличии у препарата слабого контрацептивного действия.\u003Cbr\u003EОтсутствуют клинические данные о применении мелатонина у больных с аутоиммунными заболеваниями, в связи с чем применение у данной категории пациентов не рекомендуется.\u003Cbr\u003EС осторожностью:\u003Cbr\u003EПрепарат Мелатонин-СЗ нужно применять с осторожностью пациентам с различной степенью почечной недостаточности.\u003Cbr\u003EСледует соблюдать осторожность в отношении пациентов, принимающих флувоксамин, который повышает концентрацию мелатонина за счет ингибирования его метаболизма изоферментами цитохрома Р450 (CYP): CYP1A2 и CYP2C19. Следует избегать такой комбинации.\u003Cbr\u003E Следует соблюдать осторожность в отношении пациентов, принимающих 5- и 8-метоксипсорален, который повышает концентрацию мелатонина вследствие ингибирования его метаболизма.\u003Cbr\u003EСледует соблюдать осторожность в отношении пациентов, принимающих циметидин, поскольку он повышает содержание мелатонина в плазме за счет ингибирования последнего.\u003Cbr\u003EСледует соблюдать осторожность в отношении пациентов, принимающих эстрогены (например, контрацептивы или заместительную гормональную терапию), которые увеличивают концентрацию мелатонина путем ингибирования их метаболизма изоферментами CYP1А1 и CYP1A2."},{"description":"","filters":[{"id":15768012,"name":"Взаимодействие"}],"isMainProperty":false,"name":"Взаимодействие","value":"Фармакокинетическое взаимодействие\u003Cbr\u003E- Известно, что в концентрациях, значительно превышающих терапевтические, мелатонин индуцирует изофермент CYP3A in vitro. Клиническое значение этого явления до конца не выяснено. В случае развития признаков индукции следует рассмотреть вопрос о снижении дозы одновременно применяемых лекарственных средств.\u003Cbr\u003E- В концентрациях, значительно превышающих терапевтические, мелатонин не индуцирует изоферменты группы CYP1A in vitro. Следовательно, взаимодействие мелатонина с другими лекарственными средствами вследствие влияния мелатонина на изоферменты группы CYP1A, по-видимому, незначимо.\u003Cbr\u003E- Метаболизм мелатонина, главным образом, опосредован изоферментами CYP1A. Следовательно, возможно взаимодействие мелатонина с другими лекарственными средствами вследствие влияния мелатонина на изоферменты группы CYP1 А.\u003Cbr\u003E-Курение способно снизить концентрацию мелатонина за счет индукции изофермента CYP1A2.\u003Cbr\u003E- Ингибиторы изоферментов CYPA2, например, хинолоны, способны повышать экспозицию мелатонина.\u003Cbr\u003E- Индукторы изофермента CYP1A2, такие как карбамазепин и рифампицин, способны снижать плазменную концентрацию мелатонина.\u003Cbr\u003E- В современной литературе имеется множество данных, касающихся влияния агонистов/антагонистов адренергических и опиоидных рецепторов, антидепрессантов, ингибиторов простагландинов, бензодиазепинов, триптофана и алкоголя на секрецию эндогенного мелатонина. Исследования взаимного влияния этих препаратов на динамику или кинетику мелатонина не проводилось.\u003Cbr\u003EФармакодинамическое взаимодействие\u003Cbr\u003E- Во время приема мелатонина не следует употреблять алкоголь, так как он снижает эффективность препарата.\u003Cbr\u003E- Мелатонин потенцирует седативное действие бензодиазепиновых и небензодиазепиновых снотворных средств, таких как залеплон, золпидем и зопиклон. В ходе клинического исследования наблюдались четкие признаки транзиторного фармакодинамического взаимодействия между мелатонином и золпидемом спустя час после их приема. Комбинированное применение может приводить к прогрессирующему расстройству внимания, памяти и координации в сравнении с монотерапией золпидемом.\u003Cbr\u003E- В ходе исследований мелатонин назначался совместно с тиоридазином и имипрамином, препаратами, которые влияют па центральную нервную систему. Ни в одном из случаев не было выявлено клинически значимого фармакокинетического взаимодействия. Тем не менее, одновременное применение с мелатонином приводило к повышению ощущения спокойствия и к затруднениям в выполнении определенных заданий в сравнении с монотерапией имипрамином, а также к усилению чувства \"помутнения в голове\", в сравнении с монотерапией тиоридазином."},{"description":"","filters":[{"id":16435314,"name":"Регистрационный номер"}],"isMainProperty":false,"name":"Регистрационный номер","value":"ЛП-004758"},{"description":"","filters":[{"id":16435315,"name":"Дата государственной регистрации"}],"isMainProperty":false,"name":"Дата государственной регистрации","value":"13.05.2019"},{"description":"","filters":[{"id":34324371,"name":"Тип препарата"},{"id":7893318,"name":"Производитель"}],"isMainProperty":false,"name":"Владелец регистрационного удостоверения","value":"Северная Звезда"},{"description":"","filters":[{"id":35771390,"name":"Изготовитель"}],"isMainProperty":false,"name":"Изготовитель","value":"Северная 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Цена с картой Яндекс Пэй 722 ₽ вместо 729
–1 %
Соннован таб. п/о плен., 3 мг, 30 шт.
Рейтинг товара: 4.6 из 5
на основе 13 оценок
С картой  Пэй
Цена с картой Яндекс Пэй 423 ₽ вместо 427
–1 %
Ново-Пассит таб. п/о плен., 10 шт., 1 уп.
Рейтинг товара: 5 из 5
на основе 10 оценок
С картой  Пэй
Цена с картой Яндекс Пэй 403 ₽ вместо 407
–1 %
Меларена таб. п/о плен., 3 мг, 30 шт.
Рейтинг товара: 4.7 из 5
на основе 11 оценок
С картой  Пэй
Цена с картой Яндекс Пэй 596 ₽ вместо 602
–1 %
СонНорм Дуо таб. п/о плен., 30 шт.
Рейтинг товара: 5 из 5
на основе 8 оценок
С картой  Пэй
Цена с картой Яндекс Пэй 506 ₽ вместо 511
–1 %
Персен таб., 40 шт.
Рейтинг товара: 4.7 из 5
на основе 54 оценки
С картой  Пэй
Цена с картой Яндекс Пэй 590 ₽ вместо 596
–1 %
Ноопепт таб., 10 мг, 50 шт.
Рейтинг товара: 4.6 из 5
на основе 89 оценок
С картой  Пэй
Цена с картой Яндекс Пэй 574 ₽ вместо 580
–14 %
Тенотен таб. д/рассас., 40 шт.
Рейтинг товара: 4.9 из 5
на основе 50 оценок
С картой  Пэй
Цена с картой Яндекс Пэй 522 ₽ вместо 527

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Инструкция

Показания к применению

При расстройстве сна, в т.ч. обусловленных нарушением ритма "сон- бодрствование", таких как десинхроноз (резкая смена часовых поясов).

Противопоказания

Гиперчувствительность к компонентам препарата, аутоиммунные заболевания, печеночная недостаточность, тяжелая почечная недостаточность, беременность, период грудного вскармливания, детский возраст до 18 лет.

Способ применения и дозы

Внутрь.
При нарушении сна - по 3 мг один раз в сутки за 30-40 минут до сна.
При десинхронозе в качестве адаптогена при смене часовых поясов - за 1 день до перелета и в последующие 2-5 дней - по 3 мг за 30-40 минут до сна.
Максимальная суточная доза - 6 мг.
Пожилые пациенты
С возрастом происходит снижение метаболизма мелатонина, что необходимо учитывать при выборе режима дозирования для пожилых пациентов.
С учетом этого у пациентов пожилого возраста, возможен прием препарата за 60-90 минут до сна.
Пациентам с тяжелой почечной недостаточностью применение препарата не рекомендуется.

Полная инструкция

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Мелатонин-СЗ таб. п/о плен., 3 мг, 60 шт., 1 уп.

4.8

(66)

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Задать вопрос

Инструкция

510 ₽

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4.8

У этого продавца: 66 оценок

•

14 отзывов

У всех продавцов: 453 оценки

•

177 отзывов

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12 апреля • Светлана

Недостатки: Купила на пробу тк от волнений-переживаний не могла заснуть. Мне отлично подошел препарат. С первой ночи, как стала принимать мягк...

8 октября 2023 • Lotta

Достоинства: Беру мелатонин именно Северной Звезды, так как он дешевле других производителей при том же эффектеНедостатки: растёт ценаКомментарий: Препарат всегда в домашней аптечке, так как часто летаю и страдаю от бессонницы при смене часовых поясов. Пью 1 таблетку за 20-30 ...

15 ноября 2023 • Шахмаметьева Регина

Достоинства: Покупаю не первый разНедостатки: Нет недостатков , единственный нюанс пить нужно его уже когда вы собираетесь лечь в кровать , и должно быть темно !! Действует мин...Комментарий: Рассчитывайте свое количество часов для полноценного сна , у всех по разному . Мне необходимо около 10 часов . Соответственно если...

17 марта • Имя скрыто

Достоинства: РаботаетНедостатки: Не выявленоКомментарий: Нравится что можно не есть целую таблетку, а разделить пополам и отколоть четвертинку когда есть необходимость

27 октября 2023 • Ольга Челпанова

Достоинства: даже при долгом применении,нет побочных действий. с ним я высыпаюсь! утром встаешь без тяжести.Недостатки: в аптеке этого производителя не купитьКомментарий: рекомендую, я хроническая сова! С ним легко засыпаю и встаю легко. есть с чем сравнивать.

21 марта • Наталья Белозерова

Достоинства: Проблемы со сном Мелатонин мне в этом очень сильно помогает рекомен

8 марта • Альбина

Достоинства: работает при жизни в мегаполисеНедостатки: цена

19 февраля • Александр Ч.

Достоинства: Хорошо засыпаюНедостатки: Нет

30 января • Marina K.

Комментарий: Со своей задачей справляется

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Описание

Мелатонин-СЗ таб. п/о плен., 3 мг, 60 шт., 1 уп.

Количество штук в упаковке, шт.: 60

Коротко о товаре

Где купить

510 ₽

Мелатонин Эвалар таб. п/о плен., 3 мг, 20 шт., 1 уп.

Мелатонин таб. п/о плен., 3 мг, 30 шт., 1 уп.

Глицин+Мелатонин Эвалар таб. п/языч., 20 шт.

Мелаксен таб., 3 мг, 24 шт.

Соннован таб. п/о плен., 3 мг, 30 шт.

Ново-Пассит таб. п/о плен., 10 шт., 1 уп.

Меларена таб. п/о плен., 3 мг, 30 шт.

СонНорм Дуо таб. п/о плен., 30 шт.

Персен таб., 40 шт.

Ноопепт таб., 10 мг, 50 шт.

Тенотен таб. д/рассас., 40 шт.

Инструкция

Показания к применению

Противопоказания

Способ применения и дозы

510 ₽

510 ₽

510 ₽