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Описание
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Элидел крем для наруж. прим. 1% туба 30г

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Вес, г: 30
Артикул Маркета
103543586849
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Рецептурный препарат
Тип препарата
Назначение
Действующее вещество
Инструкция
Внешний вид товаров и/или упаковки может быть изменён изготовителем и отличаться от изображенных на Яндекс Маркете.
Есть противопоказания, посоветуйтесь с врачом
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1 532 ₽
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–500 ₽
Промокод WOW500
Заказ от 1500₽ • до 04.08
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Элидел крем д/нар. прим.
Элидел крем для наруж. прим. 1% туба 30г
Задать вопрос
1 532 ₽
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Войдите, и станет дешевлеВ аккаунте больше скидок
Войти
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Доставка магазина
Завтра, самовывоз из аптеки  0 ₽
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ЗдравСити - сервис заказа и выдачи лекарств
Магазин•4.8 184.7K оценок
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Инструкция
Артикул Маркета
103543586849
Бренд
МЕДА Фарма
Тип препарата
лекарственный препарат
Рецептурный препарат
да
Органы и системы
кожа
Назначение
атопический дерматит, экзема
Показания к применению
Атопический дерматит (экзема); препарат показан для кратковременного и длительного лечения атопического дерматита у взрослых, подростков и детей (от 3 месяцев).
Противопоказания
Повышенная чувствительность к пимекролимусу или любым компонентам препарата; детский возраст до 3 месяцев (т. к. безопасность и эффективность применения крема Элидел у детей младше 3 месяцев не изучалась); крем Элидел не следует наносить на участки кожи, пораженные острой вирусной, бактериальной или грибковой инфекцией; с осторожностью: данных по безопасности применения крема Элидел у пациентов с синдромом Нетертона и генерализованной эритродермией нет; учитывая возможный риск повышения системной абсорбции препарата, крем Элидел не рекомендуется применять у больных с синдромом Нетертона или при тяжелых формах воспаления или поражения кожи (например, при эритродермии); так как эффективность и безопасность использования крема Элидел у пациентов с ослабленным иммунитетом не изучались, препарат не рекомендуется применять у данной категории больных; данные по безопасности длительного применения крема Элидел отсутствуют; поскольку влияние длительного применения препарата на иммунную защиту кожи и частоту развития злокачественных новообразований не изучено, крем Элидел не следует наносить на поврежденные участки кожного покрова с возможным озлокачествлением или диспластическими изменениями; в случае бактериального или грибкового поражения кожи применение крема Элидел на пораженных участках возможно только после излечения инфекции
Состав
1 г крема содержит: 10 мг пимекролимуса, а также вспомогательные вещества: натрия гидроксид 0,20 мг, лимонная кислота безводная 0,50 мг, бензиловый спирт 10,00 мг, натрия цетостеарилсульфат 10,00 мг, моно и диглицериды 20,00 мг, цетиловый спирт 40,00 мг, стеариновый спирт 40,00 мг, пропиленгликоль 50,00 мг, олеиловый спирт 100,00 мг, триглицериды среднецепочечные 150,00 мг, вода очищенная 569,30 мг.
Действующее вещество
Пимекролимус
Способ применения и дозы
Лечение следует начинать при первых проявлениях заболевания для предотвращения резкого развития его обострения; 1% крем Элидел 2 раза в день наносят тонким слоем на пораженную поверхность и осторожно втирают до полного впитывания; 1% крем Элидел можно наносить на кожу любых частей тела, включая голову, лицо, шею, а также на области опрелостей; крем Элидел следует применять 2 раза в сутки, до полного исчезновения симптомов заболевания; при сохранении выраженности симптомов через 6 недель применения препарата необходимо провести повторное обследование пациента для подтверждения диагноза атопического дерматита; после прекращения лечения, во избежание последующих обострений, при первых признаках рецидива атопического дерматита терапию следует возобновить; смягчающие средства можно применять сразу после нанесения 1% крема Элидел; однако после водных процедур смягчающие средства следует применять перед нанесением крема Элидел; учитывая очень незначительное системное всасывание пимекролимуса, ограничений общей суточной дозы наносимого препарата, площади обрабатываемой поверхности кожи или длительности лечения не существует; при попадании Элидела в глаза, на слизистые оболочки (ротовой или носовой полости) следует немедленно удалить крем и промыть глаза и слизистые проточной водой
Побочные действия
Применение 1% крема Элидел может вызывать незначительные преходящие реакции в месте нанесения, такие как чувство тепла и/или жжения. При значительной выраженности этих реакций пациентам следует проконсультироваться у врача; очень часто: жжение в месте нанесения крема; часто: местные реакции (раздражение, зуд и покраснение кожи), кожные инфекции (фолликулит); иногда: нагноение; ухудшение заболевания; простой герпес; дерматит, обусловленный вирусом простого герпеса (герпетическая экзема); контагиозный моллюск, местные реакции, такие как сыпь, боль, парестезии, шелушение, сухость, отечность, кожные папилломы, фурункулы; представленные ниже нежелательные реакции отмечались при постмаркетинговом применении препарата (оценка частоты по количеству случаев развития НЯ в неустановленной популяции); со стороны иммунной системы: очень редко — анафилактические реакции; со стороны обмена веществ (метаболические нарушения): редко- непереносимость алкоголя; со стороны кожи и ее придатков: редко- аллергические реакции (сыпь, крапивница, ангионевротический отек); изменения цвета кожи (гипопигментация, гиперпигментация); в большинстве случаев сразу же после приема алкоголя развивалось покраснение лица, сыпь, жжение, зуд или припухлость; при применении крема Элидел в редких случаях отмечалось развитие злокачественных новообразований, включая кожные и другие типы лимфом, рак кожи; причинно-следственная связь между данными нежелательными явлениями и применением препарата не установлена
Фармакологическое действие
Пимекролимус является производным макролактама аскомицина и обладает противовоспалительным действием.; пимекролимус селективно ингибирует продукцию и высвобождение цитокинов и медиаторов воспаления из Т-лимфоцитов и тучных клеток; пимекролимус специфично связывается с цитозольным рецептором макрофилином-12 и ингибирует кальцийзависимую фосфатазу - кальциневрин; ингибирование кальциневрина приводит к подавлению пролиферации Т-лимфоцитов и предотвращает транскрипцию и выработку в Т-хелперах 1 и 2 типа ранних цитокинов, таких как интерлейкин-2, интерферон-γ, интерлейкин-4, интерлейкин-5, интерлейкин- 10, фактор некроза опухоли-α и гранулоцитарно-макрофагальный колониестимулирующий фактор; пимекролимус и такролимус в равной степени подавляют вторичный иммунный ответ в изолированных клеточных колониях Т-хелперов кожи, полученных у больных с атопическим дерматитом. In vitro пимекролимус также предотвращает антиген/IgЕ-опосредованное высвобождение цитокинов и медиаторов воспаления из тучных клеток; пимекролимус не влияет на рост кератиноцитов, фибробластов и эндотелиальных клеток и, в отличие от кортикостероидов, оказывает селективное действие на клетки иммунной системы и не вызывает нарушений функции, жизнеспособности, процессов дифференциации, созревания клеток Лангерганса мышей и дендритных клеток моноцитарного происхождения у человека; препарат не оказывает влияния на дифференцировку «наивных» Т-лимфоцитов в Т-эффекторные клетки под действием клеток Лангерганса и дендритных клеток, являющуюся одним из основных механизмов специфического иммунного ответа; на экспериментальных моделях кожного воспаления была продемонстрирована высокая противовоспалительная активность пимекролимуса после его местного и системного применения; при местном применении на экспериментальных моделях аллергического контактного дерматита (АКД) пимекролимус сопоставим по эффективности с высокоактивными кортикостероидами: клобетазолом - 17- пропионатом и флутиказоном, ингибирует воспалительную реакцию в ответ на воздействие кожных раздражителей, не вызывая изменения консистенции, уплотнения и атрофии кожи; кроме того, при местном и пероральном применении на экспериментальных моделях АКД острого течения пимекролимус эффективно уменьшает кожное воспаление, зуд и выраженность гистопатологических изменений; при местном применении степень проникновения в кожу такролимуса и пимекролимуса одинаково хорошая; однако способность пимекролимуса проникать через кожу меньше, чем у такролимуса и глюкокортикостероидов. Таким образом, пимекролимус обладает селективным действием на кожу; уникальность механизма действия пимекролимуса состоит в сочетании селективного противовоспалительного действия на кожу с незначительным влиянием на системный иммунный ответ; при применении в течение 6 недель у детей от 3-х месяцев до 17 лет пимекролимус эффективно уменьшает зуд и кожное воспаление (эритему, инфильтрацию, экскориацию и лихенизацию); при длительном применении в течение 12 месяцев пимекролимус эффективно снижает частоту возникновения внезапных обострений АКД, не вызывая атрофии, раздражения и повышения гиперчувствительности кожи и не обладая фототоксическим или фотосенсибилизирующим действием
Фармакологическая группа
противовоспалительное средство для местного применения
Форма выпуска
крем
Способ применения/введения
наружный
Условия хранения
Элидел рекомендуется хранить при температуре не более 25°С. Препарат не замораживать! Срок хранения – 2 года.
Передозировка
Случаи передозировки или случайного употребления 1% крема Элидел внутрь не наблюдались.
Применение при беременности и кормлении грудью
Беременность; данных по применению 1% крема Элидел у беременных женщин нет; в экспериментальных исследованиях при местном применении препарата прямого или опосредованного повреждающего действия Элидела на течение беременности, развитие эмбриона/плода, течение родов и постнатальное развитие потомства не выявлено; следует соблюдать осторожность при назначении 1% крема Элидел беременным женщинам; однако, учитывая минимальную степень всасывания пимекролимуса при местном применении, потенциальный риск у человека считается незначительным; лактация; выделение препарата с грудным молоком после местного применения на экспериментальных моделях не изучалось; данных по содержанию пимекролимуса в грудном молоке у кормящих женщин нет; поскольку многие препараты выделяются с грудным молоком, следует соблюдать осторожность при назначении 1% крема Элидел кормящим женщинам; однако учитывая минимальную степень системного всасывания пимекролимуса при местном применении, потенциальный риск для человека считается незначительным; кормящие женщины не должны наносить 1% крем Элидел на область молочных желез; влияние крема Элидел на фертильность у мужчин и женщин не установлено.
Влияние на способность управлять транспортом и механизмами
Влияние применения крема Элидел на способность управлять автотранспортом или работать с механизмами не установлено.
Особые указания
При лечении ингибиторами кальциневрина местного применения, включая Элидел, в редких случаях отмечалось развитие злокачественных новообразований (например, кожных опухолей и лимфом); причинно-следственная связь между данными нежелательными явлениями и применением препарата не установлена; в клинических исследованиях при применении крема Элидел у 0,9% пациентов (14 из 1544) отмечалось развитие лимфоаденопатии; обычно лимфоаденопатия была обусловлена инфекционными заболеваниями и исчезала после проведения курса соответствующей антибиотикотерапии; у всех пациентов или удавалось выявить причину развития лимфоаденопатии или отмечалось исчезновение данного нежелательного явления; у больных, получающих лечение Элиделом, при развитии лимфоаденопатии необходимо установить этиологию процесса и обеспечить наблюдение за пациентами до полного исчезновения данного нежелательного явления; при неустановленной этиологии лимфоаденопатии или наличии у пациента острого мононуклеозного воспаления препарат следует отменить; при лечении кремом Элидел пациентам рекомендуется уменьшить до минимума искусственную или естественную инсоляцию кожи или полностью избегать ультрафиолетового облучения; возможное влияние применения препарата при поражениях кожи, вызванных ультрафиолетовым облучением, неизвестно
Взаимодействие
Потенциальные взаимодействия 1% крема Элидел с другими препаратами не изучались. Учитывая, что системная абсорбция пимекролимуса очень незначительна, какие-либо взаимодействия крема Элидел с препаратами для системного применения маловероятны; при применении крема Элидел у детей в возрасте 2-х лет и старше препарат не оказывал влияния на эффективность вакцинации; не рекомендуется нанесение крема на области введения вакцины до полного исчезновения местных проявлений поствакцинальной реакции; несовместимость: поскольку исследования совместимости не проводились, не рекомендуется применять препарат совместно с другими местными средствами
Регистрационный номер
П N014689/01
Дата государственной регистрации
29.10.2015
Бренд
МЕДА Фарма
Изготовитель
Meda Manufacturing
Фасовщик
Meda Manufacturing
Страна бренда
Германия
Страна-производитель
Франция
Название препарата
Элидел
Срок годности
23 мес.
Сертификат лекарственного препарата
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Атопический дерматит (экзема); препарат показан для кратковременного и длительного лечения атопического дерматита у взрослых, подростков и детей (от 3 месяцев).
Повышенная чувствительность к пимекролимусу или любым компонентам препарата; детский возраст до 3 месяцев (т. к. безопасность и эффективность применения крема Элидел у детей младше 3 месяцев не изучалась); крем Элидел не следует наносить на участки кожи, пораженные острой вирусной, бактериальной или грибковой инфекцией; с осторожностью: данных по безопасности применения крема Элидел у пациентов с синдромом Нетертона и генерализованной эритродермией нет; учитывая возможный риск повышения системной абсорбции препарата, крем Элидел не рекомендуется применять у больных с синдромом Нетертона или при тяжелых формах воспаления или поражения кожи (например, при эритродермии); так как эффективность и безопасность использования крема Элидел у пациентов с ослабленным иммунитетом не изучались, препарат не рекомендуется применять у данной категории больных; данные по безопасности длительного применения крема Элидел отсутствуют; поскольку влияние длительного применения препарата на иммунную защиту кожи и частоту развития злокачественных новообразований не изучено, крем Элидел не следует наносить на поврежденные участки кожного покрова с возможным озлокачествлением или диспластическими изменениями; в случае бактериального или грибкового поражения кожи применение крема Элидел на пораженных участках возможно только после излечения инфекции
Лечение следует начинать при первых проявлениях заболевания для предотвращения резкого развития его обострения; 1% крем Элидел 2 раза в день наносят тонким слоем на пораженную поверхность и осторожно втирают до полного впитывания; 1% крем Элидел можно наносить на кожу любых частей тела, включая голову, лицо, шею, а также на области опрелостей; крем Элидел следует применять 2 раза в сутки, до полного исчезновения симптомов заболевания; при сохранении выраженности симптомов через 6 недель применения препарата необходимо провести повторное обследование пациента для подтверждения диагноза атопического дерматита; после прекращения лечения, во избежание последующих обострений, при первых признаках рецидива атопического дерматита терапию следует возобновить; смягчающие средства можно применять сразу после нанесения 1% крема Элидел; однако после водных процедур смягчающие средства следует применять перед нанесением крема Элидел; учитывая очень незначительное системное всасывание пимекролимуса, ограничений общей суточной дозы наносимого препарата, площади обрабатываемой поверхности кожи или длительности лечения не существует; при попадании Элидела в глаза, на слизистые оболочки (ротовой или носовой полости) следует немедленно удалить крем и промыть глаза и слизистые проточной водой

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Достоинства: Недавно приобрела мазь по назначению врача, очень хорошо помогает,лечит кожу. Два раза в день утром и вечером в течение 1,5 мес. Действительно есть эффект, рекомендую.
Недостатки: Пока не обнаружены.
Комментарий: Рекомендую данную мазь к покупке,эффективное средство для лечения кожи.
Достоинства: очень помогло при атопическом дерматите на глазах. появилось, когда начала принимать акнекутан, была ужасная сухость век. сначала очень жгло, было больно глаза открывать. но постепенно, видимо, организм привык к элиделу и теперь я его на себе вообще не чувствую. советую всем, кто страдает дерматитом, это правда крутая вещь.
Недостатки: наверное, их нет :)
Достоинства: Лечебный эффект, стоимость
Недостатки: Нет
Комментарий: Мазь приобретала по назначению врача, препарат работающий, помогает убирать раздражение и воспаление на лице. Доставка 🚚 быстрая, плюс скидка на товар - спасибо 🫶 Товар и Продавца рекомендую 👍
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Войдите в аккаунтИ тогда откроется корзина, а цены на Маркете могут стать ниже
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